Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:inflammatory bowel disease
go back to main search page
Accession:DOID:0050589 term browser browse the term
Definition:An intestinal disease characterized by inflammation located in all parts of digestive tract. (DO)
Synonyms:exact_synonym: inflammatory bowel diseases
 narrow_synonym: CROHN DISEASE-ASSOCIATED GROWTH FAILURE, SUSCEPTIBILITY TO;   VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE;   regional enteritis;   ulcerative colitis
 related_synonym: Inflammatory bowel disease 1, susceptibility to
 primary_id: MESH:D015212
 xref: NCI:C3138;   OMIM:PS266600;   OMIM:PS614328
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
inflammatory bowel disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:18849144 RGD:5686819 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO RGD PMID:21939913 RGD:6767556 NCBI chr 7:24,218,116...24,221,162
Ensembl chr 7:24,218,116...24,228,756
JBrowse link
G AGT angiotensinogen ISO DNA:polymorphism: :p.M235T (human) RGD PMID:20717043 RGD:11039049 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G ANG angiogenin ISO protein:increased expression:serum RGD PMID:20629092 RGD:6892712 NCBI chr 7:78,249,479...78,262,846
Ensembl chr 7:78,243,687...78,262,866
JBrowse link
G ANO6 anoctamin 6 ISO associated with Spondylitis, Ankylosing;DNA:SNP: :rs17095830(human) RGD PMID:23308121 RGD:9684849 NCBI chr 5:76,112,428...76,337,073
Ensembl chr 5:76,113,243...76,337,073
JBrowse link
G APC APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912
JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr 2:77,005,706...77,034,583
Ensembl chr 2:77,005,706...77,038,009
JBrowse link
G ATG16L1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chr15:133,651,294...133,693,472
Ensembl chr15:133,651,286...133,706,038
JBrowse link
G B2M beta-2-microglobulin ISO RGD PMID:20015205 RGD:6482693 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582
JBrowse link
G CARD9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784
G CDH2 cadherin 2 ISO RGD PMID:7502046 RGD:734737 NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432
JBrowse link
G CRP C-reactive protein, pentraxin-related ISO RGD PMID:22483567 RGD:6482301 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G CUL2 cullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr10:57,700,667...57,829,388
Ensembl chr10:57,700,683...57,799,263
JBrowse link
G CYBA cytochrome b-245 alpha chain ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:3368442, PMID:9445163, PMID:10440830, PMID:19388116, PMID:25741868, PMID:30709874 NCBI chr 6:1,015,212...1,021,422
Ensembl chr 6:1,015,154...1,021,418
JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:14500559 RGD:5509042 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,722,164...193,906,565
JBrowse link
G FGF23 fibroblast growth factor 23 disease_progression ISO protein:increased expression:serum: RGD PMID:22551310 RGD:10044237 NCBI chr 5:66,028,591...66,038,078
Ensembl chr 5:66,028,776...66,037,739
JBrowse link
G HP haptoglobin ISO RGD PMID:16775491 RGD:5147444 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase ISO protein, mRNA:increased expression: colonic mucosa: inflamed tissue only RGD PMID:16195422 RGD:5688766 NCBI chr14:15,718,261...15,773,534
Ensembl chr14:15,718,266...15,763,710
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression RGD PMID:21864296 RGD:5685671 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:21135124 RGD:6218980 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15638228, PMID:28067908 RGD:1625756 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IFNG interferon gamma treatment ISO RGD PMID:31062617 RGD:14975125 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IGF2 insulin like growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:12548059, PMID:20683203 RGD:5509948, RGD:5509968 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:15844718 RGD:1626117 NCBI chr18:50,002,921...50,009,425 JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:22018461 RGD:7495770 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,553
JBrowse link
G IL10 interleukin 10 treatment
no_association
ISO ClinVar Annotator: match by term: Inflammatory bowel disease
DNA:SNP: :rs3024505 (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1800896 (human)
RGD
ClinVar
CTD
PMID:22511846, PMID:23291587, PMID:25741868, PMID:27468578, PMID:27783946, PMID:28411859, PMID:28492532, PMID:30290665, PMID:31062617 RGD:11534627, RGD:14975125, RGD:7364854 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL10RA interleukin 10 receptor subunit alpha ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chr 9:45,310,527...45,324,557
Ensembl chr 9:45,310,553...45,389,323
JBrowse link
G IL10RB interleukin 10 receptor subunit beta ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chr13:196,853,606...196,884,237
Ensembl chr13:196,853,469...196,884,932
JBrowse link
G IL18RAP interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 3:51,762,111...51,794,552
Ensembl chr 3:51,762,119...51,789,965
JBrowse link
G IL19 interleukin 19 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:25741868, PMID:28492532 NCBI chr 9:67,469,519...67,479,597
Ensembl chr 9:67,469,350...67,479,662
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO RGD PMID:12184521 RGD:10450573
G IL21R interleukin 21 receptor ISO protein:increased expression:gut mucosa,leukocytes, mononuclear RGD PMID:19322899 RGD:6892935 NCBI chr 3:19,447,488...19,489,201
Ensembl chr 3:19,443,344...19,489,152
JBrowse link
G IL23R interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784, PMID:23291587, PMID:26192919 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,577
JBrowse link
G IL33 interleukin 33 severity ISO RGD PMID:24491821 RGD:39938952 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL5 interleukin 5 susceptibility ISO RGD PMID:22018693 RGD:5687148 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Crohn disease-associated growth failure, susceptibility to
CTD
ClinVar
PMID:9769329, PMID:10720087, PMID:11001912, PMID:11889177, PMID:12519862, PMID:12560873, PMID:12719374, PMID:15070960, PMID:15331795, PMID:15472205, PMID:16150725, PMID:16278864, PMID:17623760 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G INAVA innate immunity activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr10:23,392,202...23,414,318
Ensembl chr10:23,392,298...23,412,712
JBrowse link
G ITGA4 integrin subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr15:86,942,054...87,028,428
Ensembl chr15:86,947,021...87,029,777
JBrowse link
G ITGAL integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 3:17,817,785...17,858,057
Ensembl chr 3:17,817,011...17,858,057
JBrowse link
G ITGB8 integrin subunit beta 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 9:89,342,245...89,450,701
Ensembl chr 9:89,341,141...89,450,679
JBrowse link
G KLKB1 kallikrein B1 ISO RGD PMID:8625762 RGD:7327139 NCBI chr15:47,071,581...47,100,272
Ensembl chr15:47,071,556...47,103,624
JBrowse link
G KRT8 keratin 8 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:15090596, PMID:25741868 NCBI chr 5:18,172,423...18,180,277
Ensembl chr 5:18,170,354...18,180,404
JBrowse link
G LTF lactotransferrin ISO RGD PMID:9791051 RGD:7243943 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,737
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO DNA:SNP: :1298A>C (human) RGD PMID:17111197 RGD:10449410 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G MUC19 mucin 19, oligomeric ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 5:71,964,131...72,069,073 JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: REGIONAL ENTERITIS
ClinVar Annotator: match by term: Inflammatory bowel disease 1, susceptibility to
CTD
ClinVar
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12512038, PMID:12557156, PMID:12577202, PMID:14765395, PMID:15024686, PMID:15190267, PMID:15198989, PMID:15571588, PMID:15770725, PMID:15967635, PMID:18240302, PMID:18489434, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22684479, PMID:23102769, PMID:24033266, PMID:25741868, PMID:26070941, PMID:26192919, PMID:26500656, PMID:28450277, PMID:28492532 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G NOS2 nitric oxide synthase 2 ISO protein:increased expression:colon (rat) RGD PMID:21958875 RGD:5508753 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NOX1 NADPH oxidase 1 ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:28492532, PMID:30709874 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,666...82,586,532
JBrowse link
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:17854592 RGD:4891931 NCBI chr18:38,942,499...39,212,791
Ensembl chr18:38,942,487...39,085,754
JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:11780721 RGD:6482691 Ensembl chr 5:8,986,461...9,007,446 JBrowse link
G PLCG2 phospholipase C gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060
JBrowse link
G POMC proopiomelanocortin ISO protein:alternative form:large intestine epithelium: alphaMSH RGD PMID:9145424, PMID:21741932 RGD:5508804, RGD:5508805 NCBI chr 3:113,661,712...113,668,558 JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11820457 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G RASSF1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24146755 NCBI chr13:32,816,156...32,825,486
Ensembl chr13:32,816,154...32,825,369
JBrowse link
G SFRP1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748
JBrowse link
G SFRP2 secreted frizzled related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,133...75,345,926
JBrowse link
G SLAMF8 SLAM family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 4:90,661,984...90,673,044
Ensembl chr 4:90,661,985...90,673,340
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO DNA:point mutation:promoter:-237C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :1730G>A (human)
RGD
CTD
PMID:16059695, PMID:16597321, PMID:21128323 RGD:5684929, RGD:5684952 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396
JBrowse link
G SLC6A14 solute carrier family 6 member 14 ISO protein:decreased expression:epithelial cell, colon RGD PMID:17065219 RGD:1625272 NCBI chr  X:95,482,494...95,507,200
Ensembl chr  X:95,482,451...95,527,340
JBrowse link
G TGFB1 transforming growth factor beta 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:28891831, PMID:29483653 RGD:14995457 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
G THEMIS thymocyte selection associated ISO DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr 1:35,333,210...35,530,710
Ensembl chr 1:35,333,454...35,519,870
JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:12184521, PMID:15086448, PMID:27793764 RGD:10450573 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFSF15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chr 1:255,328,731...255,349,508
Ensembl chr 1:255,325,936...255,349,456
JBrowse link
G TPMT thiopurine S-methyltransferase treatment ISO RGD PMID:17026564 RGD:11038726 NCBI chr 7:13,821,656...13,846,107
Ensembl chr 7:13,820,866...13,846,012
JBrowse link
G VEGFA vascular endothelial growth factor A disease_progression ISO protein:increased expression:serum,colon: RGD PMID:23642997 RGD:11079180 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
G VNN1 vanin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17145956 NCBI chr 1:31,003,338...31,023,731
Ensembl chr 1:31,000,254...31,059,345
JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 ISO protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ACE2 angiotensin I converting enzyme 2 severity ISO Ace2 inhibitor
Ace2 knockout
RGD PMID:19517214, PMID:22837003 RGD:40818307, RGD:40818410 NCBI chr  X:12,099,849...12,152,204
Ensembl chr  X:12,099,853...12,151,275
JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,018,568...124,050,366
JBrowse link
G SERPINA1 serpin family A member 1 treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,604,285...115,614,633
JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23A interleukin 23 subunit alpha severity ISO RGD PMID:26455347 RGD:11097134 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267
JBrowse link
G IL33 interleukin 33 severity
treatment
ISO RGD PMID:32156806 RGD:40400894 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:17604368, PMID:21479819 RGD:5686754, RGD:5686898 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G ADK adenosine kinase ISO RGD PMID:11123368 RGD:6482664 NCBI chr14:76,836,072...77,320,586
Ensembl chr14:76,836,095...77,322,416
JBrowse link
G ADRB3 adrenoceptor beta 3 ISO mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chr15:48,468,803...48,478,370 JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943
JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,858,975...90,907,094
JBrowse link
G ANXA1 annexin A1 ISO protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,307...226,432,287
JBrowse link
G APLN apelin ISO RGD PMID:17391779 RGD:1626177 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,748...106,246,378
JBrowse link
G APOA4 apolipoprotein A4 ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G AQP7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr10:33,098,746...33,130,245 JBrowse link
G ARG1 arginase 1 severity ISO RGD PMID:28423665 RGD:39939041 NCBI chr 1:32,006,035...32,028,983
Ensembl chr 1:32,006,038...32,028,986
JBrowse link
G ARRB1 arrestin beta 1 ISO protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,513,856...9,597,959
JBrowse link
G ATP5F1D ATP synthase F1 subunit delta treatment ISO RGD PMID:23840258 RGD:13792680 NCBI chr 2:77,216,430...77,219,301
Ensembl chr 2:77,216,433...77,222,749
JBrowse link
G BDNF brain derived neurotrophic factor ISO protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:22361727 RGD:7242194 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,211,316
JBrowse link
G CAT catalase ISO RGD PMID:21463646 RGD:5130869 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452
JBrowse link
G CCKBR cholecystokinin B receptor ISO RGD PMID:15102523 RGD:2311333 NCBI chr 9:3,409,222...3,419,513 JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO RGD PMID:18690297 RGD:2307009 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCR1 C-C motif chemokine receptor 1 ISO RGD PMID:16399111 RGD:2307162 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,220...29,233,960
JBrowse link
G CD36 CD36 molecule ISO RGD PMID:19117124 RGD:6893503 NCBI chr 9:99,685,748...99,782,296
Ensembl chr 9:99,605,181...99,782,105
JBrowse link
G CD40 CD40 molecule ISO RGD PMID:15591506 RGD:5508169 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
JBrowse link
G CHEK2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473, PMID:11053450, PMID:11479205, PMID:11719428, PMID:11967536, PMID:12094328, PMID:12533788, PMID:12690581, PMID:14648717, PMID:14648718, PMID:14648719, PMID:15122511, PMID:15488637, PMID:15492928, PMID:15520402, PMID:16257342, PMID:16492927, PMID:16880452, PMID:17085682, PMID:18172190, PMID:19338683, PMID:19805189, PMID:21807500, PMID:21956126, PMID:22006311, PMID:22058428, PMID:22419737, PMID:22811390, PMID:22994785, PMID:23469205, PMID:24033266, PMID:24884479, PMID:25431674, PMID:25741868, PMID:26084796, PMID:26467025, PMID:26641009, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26884562, PMID:27083775, PMID:27153395, PMID:27269948, PMID:27433846, PMID:27751358, PMID:27798748, PMID:28125075, PMID:28135145, PMID:28195393, PMID:28492532, PMID:28503720, PMID:28514723, PMID:28727877, PMID:28734145, PMID:28779002, PMID:28802053, PMID:28874143, PMID:29351919, PMID:29489754, PMID:30311386 NCBI chr14:45,699,833...45,967,350
Ensembl chr14:45,926,613...45,967,296
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr14:111,316,178...111,351,669
Ensembl chr14:111,307,610...111,351,712
JBrowse link
G CIITA class II major histocompatibility complex transactivator severity ISO protein:increased expression:T cells:constitutive expression of transgene increases severity
ClinVar Annotator: match by term: Colitis
RGD
ClinVar
PMID:17043423, PMID:25741868, PMID:28492532 RGD:5491188 NCBI chr 3:32,171,706...32,230,775
Ensembl chr 3:32,172,214...32,230,780
JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086, PMID:21330446 RGD:5131259, RGD:5490987 NCBI chr18:42,251,755...42,296,457
Ensembl chr18:42,251,749...42,295,468
JBrowse link
G CTSB cathepsin B ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,034,737
JBrowse link
G CTSL cathepsin L ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr10:27,668,523...27,674,705
Ensembl chr10:27,668,264...27,674,618
JBrowse link
G CTSS cathepsin S ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr 4:98,415,273...98,442,952
Ensembl chr 4:98,390,250...98,442,936
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO associated with Helicobacter Infections;mRNA:decreased expression:colon (mouse, Helicobacter hepaticus) RGD PMID:17242461 RGD:38549339 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO RGD PMID:14738862 RGD:7257706 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYP1A1 cytochrome P450 1A1 ISO mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,780,105...58,809,755
JBrowse link
G DUSP1 dual specificity phosphatase 1 severity ISO RGD PMID:22461024 RGD:7771532 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,722,164...193,906,565
JBrowse link
G FGF19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 2:3,583,027...3,586,985
Ensembl chr 2:3,583,027...3,587,825
JBrowse link
G FLNA filamin A ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868, PMID:28492532 NCBI chr  X:124,889,934...124,915,000
Ensembl chr  X:124,890,142...124,917,171
JBrowse link
G GCG glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,561...68,810,244
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,316,436...66,452,917
JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chr16:66,162,318...66,208,868 JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO protein:increased expression:colon:
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16365149, PMID:21444764, PMID:21853095, PMID:22261574 RGD:10766442, RGD:7207796
G HP haptoglobin treatment ISO RGD PMID:22457771 RGD:11041866 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G ICOS inducible T cell costimulator ISO protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chr15:107,350,253...107,370,123
Ensembl chr15:107,350,203...107,370,123
JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr17:11,289,607...11,348,557
Ensembl chr17:11,289,690...11,348,553
JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:19238344, PMID:21807089, PMID:21949848, PMID:22119709, PMID:22461024, PMID:23771723, PMID:24314293 RGD:7349385, RGD:7365024, RGD:7771532 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL17A interleukin 17A ISO mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:14962796, PMID:20881082, PMID:24548422 RGD:4781448, RGD:4888509 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
JBrowse link
G IL1RL1 interleukin 1 receptor like 1 severity ISO RGD PMID:23172891 RGD:40400694 NCBI chr 3:51,868,549...51,902,454
Ensembl chr 3:51,803,165...51,951,383
JBrowse link
G IL33 interleukin 33 severity ISO RGD PMID:23172891, PMID:28423665 RGD:39939041, RGD:40400694 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:9389741, PMID:24314293 RGD:8142400 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL5 interleukin 5 ISO protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chr 2:134,832,143...134,846,141
Ensembl chr 2:134,832,147...134,835,212
JBrowse link
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22410118, PMID:24548422 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G ITGB2 integrin subunit beta 2 ISO associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chr13:207,514,281...207,544,108
Ensembl chr13:207,512,954...207,544,108
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G LOC100625897 lactase-phlorizin hydrolase ISO protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chr15:16,094,277...16,154,467 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:22969190, PMID:23810507, PMID:24548422 RGD:7204699
G LRRK2 leucine rich repeat kinase 2 ISO RGD PMID:21983832 RGD:5508401 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,240...71,944,938
JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chr 2:77,784,610...77,789,036 JBrowse link
G MC1R melanocortin 1 receptor ISO RGD PMID:16543288 RGD:5687320 NCBI chr 6:181,225...182,187
Ensembl chr 6:181,225...182,187
JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:12105854, PMID:17324399 RGD:1641979 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,862,317
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
JBrowse link
G MSH2 mutS homolog 2 ISO RGD PMID:23883737 RGD:10412318 NCBI chr 3:93,082,958...93,163,556
Ensembl chr 3:93,081,219...93,163,628
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming treatment ISO mRNA:decreased expression:colon
protein:decreased sulfation:descending colon
RGD PMID:12395902, PMID:19220658, PMID:21949848, PMID:23395625 RGD:2324675, RGD:7349356, RGD:7349360, RGD:7349385 NCBI chr 2:689,363...719,542 JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr 9:106,119,896...106,162,126
Ensembl chr 9:106,119,899...106,294,587
JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:20921147 RGD:5508755 NCBI chr18:42,464,667...42,509,135
Ensembl chr18:42,432,050...42,512,266
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:colon RGD PMID:16891783, PMID:20921147, PMID:21471573 RGD:1600781, RGD:5508727, RGD:5508755 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G NOS2 nitric oxide synthase 2 ISO mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon (mouse)
RGD
CTD
PMID:8698225, PMID:16866779, PMID:17449036, PMID:21930116 RGD:4891411, RGD:5509045 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,944...44,327,111
JBrowse link
G NOS3 nitric oxide synthase 3 ISO mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,156...6,228,938
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,237,930
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,379...30,429,882
JBrowse link
G PGF placental growth factor ISO RGD PMID:20142801 RGD:6483587 NCBI chr 7:98,149,510...98,162,784 JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21244371 RGD:6482682 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099
JBrowse link
G PLA2G2A phospholipase A2 group IIA ISO RGD PMID:17982090 RGD:6482729 NCBI chr 6:78,327,728...78,339,546
Ensembl chr 6:78,327,319...78,330,699
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha susceptibility ISO RGD PMID:20650341 RGD:5509936 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:22126533 RGD:6484264 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,961,909
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:20833794 RGD:6483551 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11820457, PMID:17543437 RGD:2298659 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18623154, PMID:23810507 RGD:2298776 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G RETN resistin treatment ISO RGD PMID:22630819 RGD:7207222 NCBI chr 2:71,484,164...71,485,577
Ensembl chr 2:71,484,169...71,485,616
JBrowse link
G SELL selectin L ISO RGD PMID:18054560 RGD:5685703 NCBI chr 4:81,306,363...81,325,296
Ensembl chr 4:81,306,373...81,326,778
JBrowse link
G SELP selectin P ISO protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,406,203
JBrowse link
G SELPLG selectin P ligand ISO RGD PMID:22009715 RGD:6218987 NCBI chr14:42,158,694...42,178,044 JBrowse link
G SI sucrase-isomaltase ISO mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chr13:104,296,281...104,379,558
Ensembl chr13:104,296,283...104,379,478
JBrowse link
G SIRT1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103, PMID:24548422, PMID:24782617 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,157...71,123,299
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:19016783 RGD:5684975 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860
JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526
JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 3:67,839,367...68,021,733
Ensembl chr 3:67,839,411...68,021,728
JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12490601, PMID:18715640 RGD:2304260, RGD:5147478 NCBI chr14:72,463,405...72,476,034
Ensembl chr14:72,462,046...72,475,554
JBrowse link
G TFF1 trefoil factor 1 ISO RGD PMID:8836141 RGD:625375 NCBI chr13:205,687,558...205,691,512 JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,816...12,242,637
JBrowse link
G TLR3 toll like receptor 3 ISO mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chr15:46,966,262...46,977,774
Ensembl chr15:46,966,040...47,058,734
JBrowse link
G TLR4 toll like receptor 4 ISO protein:increased expression:colon RGD PMID:19002562, PMID:19924809 RGD:2312573, RGD:7794773 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507, PMID:24548422 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TST thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chr 5:10,749,264...10,759,623
Ensembl chr 5:10,746,890...10,759,623
JBrowse link
G UCN urocortin ISO mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chr 3:111,834,082...111,835,932 JBrowse link
G UCN2 urocortin 2 ISO mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chr13:31,261,196...31,261,824
Ensembl chr13:31,261,196...31,261,534
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226
JBrowse link
G VIP vasoactive intestinal peptide ISO associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269
JBrowse link
G VIPR2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:21295288 RGD:5685384 NCBI chr18:396,379...466,408
Ensembl chr18:396,263...518,102
JBrowse link
Crohn's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16432373, PMID:21829567 RGD:5686726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G AGT angiotensinogen ISO ClinVar Annotator: match by term: Crohn disease, association with ClinVar PMID:9120024, PMID:9894356, PMID:13937884, PMID:15077204, PMID:17047091, PMID:20978123 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,672,428
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G APLN apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,748...106,246,378
JBrowse link
G APOA4 apolipoprotein A4 severity ISO protein:decreased expression:blood plasma (human) RGD PMID:17206692 RGD:5685660 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G AQP7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr10:33,098,746...33,130,245 JBrowse link
G ATG16L1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756, PMID:18438406 NCBI chr15:133,651,294...133,693,472
Ensembl chr15:133,651,286...133,706,038
JBrowse link
G BACH2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 1:57,881,203...58,281,740
Ensembl chr 1:57,899,789...58,204,839
JBrowse link
G BGLAP bone gamma-carboxyglutamate protein ISO protein:undercarboxylated:serum
mRNA:decreased expression:bone
RGD PMID:21482072, PMID:22535626 RGD:6483321, RGD:6483546 NCBI chr 4:93,807,703...93,808,806
Ensembl chr 4:93,807,706...93,836,791
JBrowse link
G BPI bactericidal permeability increasing protein ISO RGD PMID:15758620 RGD:1580079 NCBI chr17:41,344,878...41,392,103
Ensembl chr17:41,344,939...41,392,100
JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,028
JBrowse link
G CCNY cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr10:57,929,484...58,057,964
Ensembl chr10:57,929,131...58,086,872
JBrowse link
G CD40 CD40 molecule susceptibility ISO DNA:SNP:5' utr:c.-1C>T (rs1883832) (human)
protein:increased expression:intestine, epithelial cell
RGD PMID:20133813, PMID:20634952 RGD:5490590, RGD:5490971 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
JBrowse link
G CIBAR2 CBY1 interacting BAR domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr 6:3,709,429...3,720,199
Ensembl chr 6:3,710,213...3,720,198
JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:21748286 RGD:11341809 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,767...127,730,657
JBrowse link
G CRP C-reactive protein, pentraxin-related severity ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum
CTD
RGD
PMID:11339241, PMID:22421709 RGD:6482309 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,722,352...90,805,236
JBrowse link
G DENND1B DENN domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr10:20,391,507...20,635,808
Ensembl chr10:20,395,462...20,636,247
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 3:113,501,972...113,609,148
Ensembl chr 3:113,528,926...113,609,139
JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 2:103,510,425...103,563,482
Ensembl chr 2:103,510,440...103,564,441
JBrowse link
G ESR2 estrogen receptor 2 disease_progression ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,722,164...193,906,565
JBrowse link
G F13A1 coagulation factor XIII A chain ISO associated with Fistula;protein:decreased activity:plasma: RGD PMID:7611208 RGD:10450739 NCBI chr 7:3,751,290...3,900,797
Ensembl chr 7:3,751,291...3,900,765
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa treatment ISO DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14987319 RGD:1304543 NCBI chr 4:88,948,357...88,956,513 JBrowse link
G FGA fibrinogen alpha chain ISO RGD PMID:19683480 RGD:5688758 NCBI chr 8:74,574,870...74,584,202
Ensembl chr 8:74,574,882...74,584,202
JBrowse link
G FN1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G FUT2 fucosyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 6:54,034,666...54,044,891
Ensembl chr 6:54,034,684...54,047,224
JBrowse link
G GC GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,301...68,360,262
JBrowse link
G GPBAR1 G protein-coupled bile acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23566200 NCBI chr15:120,336,196...120,339,506
Ensembl chr15:120,336,488...120,339,505
JBrowse link
G GPX1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G HFE homeostatic iron regulator treatment ISO DNA:SNP: :rs2071303 (human) RGD PMID:27115882 RGD:14701051 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,768,741
JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chr 7:23,909,960...23,938,678
Ensembl chr 7:23,909,960...23,921,723
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:15638228 RGD:1625756 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21829567, PMID:28070144 RGD:14974261 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,037
JBrowse link
G IL10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11113068, PMID:21102463, PMID:29899181 RGD:11049181, RGD:14975133 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL12B interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,147,247...64,158,952
JBrowse link
G IL21R interleukin 21 receptor ISO DNA:altered methylation: : RGD PMID:22021194 RGD:6482789 NCBI chr 3:19,447,488...19,489,201
Ensembl chr 3:19,443,344...19,489,152
JBrowse link
G IL23R interleukin 23 receptor susceptibility ISO DNA:SNPs:multiple:
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:17068223, PMID:17435756, PMID:18438406 RGD:8549568 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,577
JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,552...65,001,173
JBrowse link
G IL6 interleukin 6 ISO OMIM NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G JAK2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human) RGD PMID:22269120 RGD:6483020 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G LEP leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,447
JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO DNA:point mutation: :p.T2397M (rs3761863) (human) RGD PMID:21983832 RGD:5508401 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,240...71,944,938
JBrowse link
G MADCAM1 mucosal vascular addressin cell adhesion molecule 1 ISO RGD PMID:11703369 RGD:2311550 NCBI chr 2:77,784,610...77,789,036 JBrowse link
G MBL2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:cds: RGD PMID:21702710 RGD:12910842 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,894...97,108,936
JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:decreased expression:feces RGD PMID:29325325, PMID:29668922, PMID:30927737 RGD:21079443, RGD:24922207, RGD:24922213 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MKI67 marker of proliferation Ki-67 ISO RGD PMID:21364546 RGD:6483536 NCBI chr14:137,266,622...137,296,312 JBrowse link
G MST1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr13:32,214,934...32,220,045
Ensembl chr13:32,214,937...32,219,902
JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28002332 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,636...71,881,820
JBrowse link
G NCF4 neutrophil cytosolic factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr 5:10,876,147...10,994,002
Ensembl chr 5:10,874,953...10,994,015
JBrowse link
G NKX2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438405, PMID:18438406 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,397...110,724,001
JBrowse link
G NLRP3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19098911 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,242...56,977,234
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 no_association
susceptibility
ISO DNA:missense mutations, frameshift mutation: :p.R702W, p.G908R, 3020_3021insC (human)
DNA:frameshift mutation, missense mutations
OMIM
RGD
PMID:11385576, PMID:21155887 RGD:1600778, RGD:5508730 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,288...83,684,604
JBrowse link
G OCLN occludin ISO RGD PMID:21748286 RGD:11341809 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,498...47,654,033
JBrowse link
G PGF placental growth factor ISO protein:increased expression:serum RGD PMID:17980128 RGD:6483592 NCBI chr 7:98,149,510...98,162,784 JBrowse link
G PHOX2B paired like homeobox 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr 8:32,841,425...32,846,133
Ensembl chr 8:32,841,396...32,846,215
JBrowse link
G PLAUR plasminogen activator, urokinase receptor ISO RGD PMID:21114432 RGD:6483800 NCBI chr 6:50,489,773...50,505,453
Ensembl chr 6:50,489,777...50,505,418
JBrowse link
G PON1 paraoxonase 1 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PON3 paraoxonase 3 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,983,040...75,017,947
Ensembl chr 9:74,991,277...75,017,942
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,708...3,366,361
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,655...68,433,947
JBrowse link
G PRF1 perforin 1 ISO DNA:hypermethylation RGD PMID:22021194 RGD:6482789 NCBI chr14:73,515,306...73,520,256
Ensembl chr14:73,512,769...73,520,202
JBrowse link
G PRKCQ protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,443,251...64,600,339
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:colon RGD PMID:21763290 RGD:5508200 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,251...96,847,133
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 ISO DNA:SNP:cds:rs2476601 (human) RGD PMID:18587394 RGD:6484668 NCBI chr 4:106,692,102...106,758,101
Ensembl chr 4:106,686,604...106,758,099
JBrowse link
G SELL selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr 4:81,306,363...81,325,296
Ensembl chr 4:81,306,373...81,326,778
JBrowse link
G SLC11A1 solute carrier family 11 member 1 no_association ISO DNA:point mutation:promoter:-237C>T (human)
DNA:repeat, polymorphisms:promoter, intron:p.D543N (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
DNA:polymorphism: :823C>T (human)
DNA:polymorphisms:promoter (human)
DNA:insertion/deletion:3' utr (human)
RGD
CTD
PMID:11929588, PMID:15757519, PMID:16059695, PMID:17131479, PMID:17385031, PMID:18340647, PMID:18454481 RGD:5684938, RGD:5684939, RGD:5684941, RGD:5684942, RGD:5684952, RGD:5684956, RGD:5684968 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396
JBrowse link
G SLC22A5 solute carrier family 22 member 5 susceptibility ISO DNA:snp, haplotype:promoter:g.-207G>C (human) RGD PMID:15107849 RGD:1580609 NCBI chr 2:134,660,741...134,847,575 JBrowse link
G SMAD3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,083...165,124,454
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
DNA:SNPs: :rs744166, rs3816769 (human)
RGD PMID:20109474, PMID:22269120 RGD:6483020, RGD:6483027 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G TAGAP T cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 1:8,209,298...8,217,993
Ensembl chr 1:8,208,084...8,219,630
JBrowse link
G TCF7 transcription factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24994854 NCBI chr 2:136,422,740...136,456,323
Ensembl chr 2:136,422,712...136,458,037
JBrowse link
G THBD thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,221,819...30,230,177
JBrowse link
G TLR4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17914947 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
G TLR9 toll like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15236225, PMID:17914947 NCBI chr13:34,353,444...34,370,990 JBrowse link
G TNF tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:intestine mucosa
CTD
RGD
PMID:10700533, PMID:21359923, PMID:21829567, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,073...64,331,909
JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923 RGD:5130893 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,149
JBrowse link
G TYK2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 2:69,157,774...69,183,555
Ensembl chr 2:69,157,799...69,183,461
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr13:26,036,610...26,073,168
Ensembl chr13:26,036,629...26,075,691
JBrowse link
G VTN vitronectin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr12:44,650,532...44,653,916
Ensembl chr12:44,617,499...44,660,271
JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment ISO RGD PMID:17342403, PMID:24239644 RGD:40400720, RGD:40400748 NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,639
JBrowse link
G ACER3 alkaline ceramidase 3 severity ISO mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296 RGD:35673322 NCBI chr 9:10,985,078...11,167,386
Ensembl chr 9:10,951,561...11,165,493
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:11884025 RGD:632022 NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G ADRB3 adrenoceptor beta 3 no_association ISO mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chr15:48,468,803...48,478,370 JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha treatment ISO RGD PMID:25689466 RGD:13703055 NCBI chr 1:95,738,789...95,750,835
Ensembl chr 1:95,625,800...95,750,875
JBrowse link
G CSF3 colony stimulating factor 3 treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:29655167 RGD:39939058 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G EREG epiregulin ISO protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chr 8:70,351,316...70,372,530
Ensembl chr 8:70,351,309...70,372,518
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:22368862 RGD:10054108 NCBI chr14:100,927,305...100,954,781 JBrowse link
G FOXP3 forkhead box P3 treatment ISO mRNA:increased expression:mucosa:
protein:increased expression:colon:
RGD PMID:17229795, PMID:26925602, PMID:27498708, PMID:28733028 RGD:14975101, RGD:38455994, RGD:38455995, RGD:38549362 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,782...43,328,735
JBrowse link
G HAMP hepcidin antimicrobial peptide ISO protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,159...44,787,307
JBrowse link
G HSF1 heat shock transcription factor 1 ISO protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chr 4:463,531...486,483
Ensembl chr 4:461,559...486,473
JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10092309 RGD:11522714 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G IFNG interferon gamma ISO protein:increased expression:plasma: RGD PMID:15030379, PMID:27498708 RGD:10755756, RGD:14975101 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G IL10 interleukin 10 treatment ISO associated with Helicobacter Infections RGD PMID:16982822, PMID:25727887, PMID:27815529 RGD:11049170, RGD:11049485, RGD:14975260 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835
G IL2 interleukin 2 ISO RGD PMID:16630696 RGD:8662978 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609
JBrowse link
G IL23A interleukin 23 subunit alpha severity ISO mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267
JBrowse link
G IL33 interleukin 33 severity
treatment
ISO RGD PMID:25112700, PMID:28423665 RGD:39938951, RGD:39939041 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL6 interleukin 6 treatment ISO RGD PMID:16133010, PMID:16630696, PMID:27096537 RGD:11062139, RGD:11062146, RGD:8662978 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,340...91,511,263
JBrowse link
G ITGA2 integrin subunit alpha 2 treatment ISO RGD PMID:16534417 RGD:11530069 NCBI chr16:32,336,240...32,440,311
Ensembl chr16:32,336,292...32,437,103
JBrowse link
G ITGA4 integrin subunit alpha 4 ISO protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chr15:86,942,054...87,028,428
Ensembl chr15:86,947,021...87,029,777
JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 ISO mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chr14:79,345,382...80,106,337
Ensembl chr14:79,352,396...80,106,258
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G KL klotho ISO mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chr11:9,427,236...9,479,251
Ensembl chr11:9,427,198...9,478,346
JBrowse link
G LOC110258578 interleukin-1 beta-like treatment ISO RGD PMID:31175857 RGD:14975282
G MAPK1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:27028006 RGD:13800882 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,523
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29037916 RGD:13800567 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567
JBrowse link
G MIF macrophage migration inhibitory factor severity ISO RGD PMID:15807847 RGD:36947390 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,862,317
JBrowse link
G MIR155 microRNA mir-155 treatment ISO associated with Helicobacter Infections RGD PMID:21880981, PMID:28246471, PMID:28461115, PMID:28752563, PMID:30253332, PMID:30927737 RGD:21079443, RGD:21079463, RGD:21079473, RGD:21081536, RGD:24922208, RGD:25314295 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,594...30,086,982
JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G MYDGF myeloid derived growth factor severity
treatment
ISO associated with hymenolepiasis RGD PMID:19118508, PMID:20490892, PMID:27055194 RGD:11532263, RGD:39456118, RGD:39456129 NCBI chr 2:74,185,042...74,202,306
Ensembl chr 2:74,185,037...74,202,301
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 treatment ISO RGD PMID:22350949 RGD:10412739 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:21642017 RGD:10413866 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,508,016...64,558,057
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G NPY neuropeptide Y treatment ISO RGD PMID:20533056 RGD:10448943 NCBI chr18:47,985,796...47,993,726
Ensembl chr18:47,985,725...47,993,289
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr 8:40,966,568...41,021,440
Ensembl chr 8:40,967,493...41,021,442
JBrowse link
G PDGFRB platelet derived growth factor receptor beta treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr 2:151,155,753...151,192,818
Ensembl chr 2:151,155,754...151,192,647
JBrowse link
G PHEX phosphate regulating endopeptidase homolog X-linked ISO mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chr  X:18,199,396...18,420,985
Ensembl chr  X:18,203,174...18,418,004
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma susceptibility ISO RGD PMID:20347874 RGD:38599183 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099
JBrowse link
G PTGER4 prostaglandin E receptor 4 treatment ISO RGD PMID:12100473 RGD:727388 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO RGD PMID:19116231 RGD:5684934 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396
JBrowse link
G SMAD4 SMAD family member 4 susceptibility ISO RGD PMID:23090737 RGD:12880038 NCBI chr 1:100,521,843...100,633,501
Ensembl chr 1:100,514,791...100,628,029
JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chr 5:64,319,349...64,331,876
Ensembl chr 5:64,319,073...64,331,909
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
ileitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:22848538 RGD:8661712 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:21945903 RGD:6892917 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CD80 CD80 molecule ISO RGD PMID:22068168 RGD:6902902 NCBI chr13:140,693,312...140,730,541
Ensembl chr13:140,693,382...140,728,980
JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL17A interleukin 17A ISO mRNA:increased expression:ileum RGD PMID:18536735 RGD:4837793 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
JBrowse link
G ITGAM integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:10647630 NCBI chr 3:17,216,719...17,272,134
Ensembl chr 3:17,136,161...17,273,657
JBrowse link
G SERPINA1 serpin family A member 1 treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,604,285...115,614,633
JBrowse link
G TLR2 toll like receptor 2 ISO RGD PMID:18266231 RGD:2312714 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TLR4 toll like receptor 4 ISO RGD PMID:17255219, PMID:18266231 RGD:2312714, RGD:7241089 NCBI chr 1:258,044,610...258,054,641
Ensembl chr 1:258,044,610...258,059,004
JBrowse link
inflammatory bowel disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA1L heat shock protein family A (Hsp70) member 1 like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chr 7:23,909,960...23,938,678
Ensembl chr 7:23,909,960...23,921,723
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12115249, PMID:12512038, PMID:12557156, PMID:12577202, PMID:12626759, PMID:12630966, PMID:14508222, PMID:14765395, PMID:15024686, PMID:15044951, PMID:15190267, PMID:15198989, PMID:15320482, PMID:15459013, PMID:15571588, PMID:15712650, PMID:15770725, PMID:15967635, PMID:16278823, PMID:16485124, PMID:18056399, PMID:18240302, PMID:18419343, PMID:18489434, PMID:18507017, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20032092, PMID:20230816, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22319155, PMID:22684479, PMID:22926499, PMID:22942351, PMID:23102769, PMID:24033266, PMID:24391456, PMID:24583628, PMID:24803813, PMID:24960071, PMID:25741868, PMID:26070941, PMID:26164256, PMID:26316104, PMID:26500656, PMID:27306066, PMID:28492532, PMID:28814775 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G PRKCQ protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chr10:64,442,588...64,596,528
Ensembl chr10:64,443,251...64,600,339
JBrowse link
inflammatory bowel disease 10 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG16L1 autophagy related 16 like 1 ISO OMIM NCBI chr15:133,651,294...133,693,472
Ensembl chr15:133,651,286...133,706,038
JBrowse link
inflammatory bowel disease 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO OMIM NCBI chr 9:93,049,955...93,146,469 JBrowse link
inflammatory bowel disease 14 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF5 interferon regulatory factor 5 ISO OMIM NCBI chr18:19,678,377...19,691,154
Ensembl chr18:19,678,686...19,691,154
JBrowse link
inflammatory bowel disease 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL23R interleukin 23 receptor ISO OMIM NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,577
JBrowse link
inflammatory bowel disease 25 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10RB interleukin 10 receptor subunit beta ISO OMIM NCBI chr13:196,853,606...196,884,237
Ensembl chr13:196,853,469...196,884,932
JBrowse link
inflammatory bowel disease 28 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10RA interleukin 10 receptor subunit alpha ISO OMIM NCBI chr 9:45,310,527...45,324,557
Ensembl chr 9:45,310,553...45,389,323
JBrowse link
Inflammatory Bowel Disease 29 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INAVA innate immunity activator ISO OMIM NCBI chr10:23,392,202...23,414,318
Ensembl chr10:23,392,298...23,412,712
JBrowse link
inflammatory bowel disease 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 5 ClinVar PMID:15107849, PMID:16333318, PMID:17213842 NCBI chr 2:134,660,741...134,847,575 JBrowse link
INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TGFB1 transforming growth factor beta 1 ISO OMIM NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,169...49,349,048
JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SERPINE1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G VEGFA vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 ISO OMIM NCBI chr 3:126,795,513...126,853,995
Ensembl chr 3:126,795,426...126,853,995
JBrowse link
G IAH1 isoamyl acetate hydrolyzing esterase 1 (putative) ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal 1 ClinVar PMID:28492532 NCBI chr 3:126,853,774...126,865,783
Ensembl chr 3:126,849,443...126,865,735
JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGFR epidermal growth factor receptor ISO OMIM NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,478,882
JBrowse link
Pediatric Crohn's Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO RGD PMID:21287673 RGD:5147769 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:increased expression:duodenal mucosa RGD PMID:27468194 RGD:25671466 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:11321389 RGD:7394742 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RN interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ACSM3 acyl-CoA synthetase medium chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chr 3:25,247,723...25,284,063
Ensembl chr 3:25,247,722...25,283,709
JBrowse link
G ADCY7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chr 6:34,521,503...34,586,384
Ensembl chr 6:34,519,180...34,585,779
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,684...124,646,648
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chr 2:150,032,649...150,035,591
Ensembl chr 2:150,032,782...150,035,591
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G APLN apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:106,236,746...106,246,563
Ensembl chr  X:106,236,748...106,246,378
JBrowse link
G APOA4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human) RGD PMID:17206692 RGD:5685660 NCBI chr 9:44,201,587...44,204,072
Ensembl chr 9:44,201,508...44,204,206
JBrowse link
G AQP7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr10:33,098,746...33,130,245 JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G BRINP3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chr10:2,963,237...3,367,629
Ensembl chr10:2,963,527...3,367,623
JBrowse link
G BTNL2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chr 7:24,789,988...24,809,920
Ensembl chr 7:24,790,001...24,809,854
JBrowse link
G CARD9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799
G CASP3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,749...45,763,773
JBrowse link
G CCL20 C-C motif chemokine ligand 20 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16306769, PMID:21887805 RGD:7488892 NCBI chr15:129,172,743...129,176,069 JBrowse link
G CCNY cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr10:57,929,484...58,057,964
Ensembl chr10:57,929,131...58,086,872
JBrowse link
G CCR3 C-C motif chemokine receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,251,959...29,376,346
JBrowse link
G CCR6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chr 1:2,016,600...2,034,172
Ensembl chr 1:2,018,608...2,019,821
JBrowse link
G CD40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528
JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
JBrowse link
G CDH3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 6:18,190,971...18,236,184
Ensembl chr 6:18,191,664...18,235,862
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chr 7:32,354,776...32,363,771
Ensembl chr 7:32,359,455...32,363,761
JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain ISO Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chr13:207,907,835...207,984,082
Ensembl chr13:207,907,857...207,985,181
JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,003
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12133438, PMID:15955209 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chr  X:57,592,032...57,595,706
Ensembl chr  X:57,592,038...57,595,692
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chr15:15,663,652...15,666,706
Ensembl chr15:15,663,494...15,667,233
JBrowse link
G DAP death associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr16:250,212...322,075 JBrowse link
G ECM1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 4:98,615,776...98,633,081
Ensembl chr 4:98,615,778...98,633,515
JBrowse link
G ESR2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,722,164...193,906,565
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,451...15,819,138
JBrowse link
G FAS Fas cell surface death receptor treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr14:100,927,305...100,954,781 JBrowse link
G FASLG Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,475
JBrowse link
G GC GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr 8:68,326,293...68,360,262
Ensembl chr 8:68,326,301...68,360,262
JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,316,436...66,452,917
JBrowse link
G GNA12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 3:2,002,494...2,105,937
Ensembl chr 3:2,000,863...2,105,949
JBrowse link
G GPR65 G protein-coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chr 7:109,978,913...109,997,688 JBrowse link
G GPX1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,914,932...31,917,335
JBrowse link
G HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr15:56,438,117...56,649,805
Ensembl chr15:56,438,107...56,649,796
JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,503
JBrowse link
G HNMT histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chr15:13,733,412...13,768,106
Ensembl chr15:13,732,680...13,768,199
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chr 2:135,345,724...135,391,112
Ensembl chr 2:135,305,749...135,394,185
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO mRNA:increased expression:substantia nigra (rat)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:15553846, PMID:20584104 RGD:4145388 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G ICOSLG inducible T cell costimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:207,106,202...207,115,886 JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,925...137,690,666
JBrowse link
G IGF2 insulin like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chr 2:1,469,183...1,496,417 JBrowse link
G IKZF1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 9:136,372,202...136,464,942
Ensembl chr 9:136,372,724...136,464,942
JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18836448, PMID:20228799, PMID:26660358, PMID:28120341 RGD:14975153, RGD:14975255 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,727...67,405,711
JBrowse link
G IL12B interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799, PMID:21297633 NCBI chr16:64,143,268...64,158,929
Ensembl chr16:64,147,247...64,158,952
JBrowse link
G IL17REL interleukin 17 receptor E like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228798 NCBI chr 5:645,882...662,552 JBrowse link
G IL18RAP interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 3:51,762,111...51,794,552
Ensembl chr 3:51,762,119...51,789,965
JBrowse link
G IL1R2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 3:52,367,434...52,406,393
Ensembl chr 3:52,367,437...52,406,334
JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136
G IL23R interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism
DNA:SNP,Haplotype: :rs1884444(human)
CTD
RGD
PMID:18438406, PMID:19122664, PMID:20228799, PMID:23093364 RGD:8549574 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,577
JBrowse link
G IL33 interleukin 33 severity
treatment
ISO mRNA:increased expression:sigmoid colon RGD PMID:21037074, PMID:25112700, PMID:28802904 RGD:39938951, RGD:39938966, RGD:40813742 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,435...215,941,840
JBrowse link
G IL7R interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr16:21,300,141...21,330,156
Ensembl chr16:21,300,111...21,329,585
JBrowse link
G IRF5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr18:19,678,377...19,691,154
Ensembl chr18:19,678,686...19,691,154
JBrowse link
G JAK2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:20228799, PMID:21297633, PMID:22269120 RGD:6483020 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,686...217,002,148
JBrowse link
G KDR kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,116...41,856,339
JBrowse link
G KIF21B kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:23,444,997...23,491,081
Ensembl chr10:23,444,998...23,491,185
JBrowse link
G LAMB1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 9:107,670,120...107,747,242
Ensembl chr 9:107,671,152...107,772,269
JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD
RGD
PMID:12133438, PMID:15955209, PMID:20452301, PMID:22119283, PMID:24812904 RGD:10450593
G LSP1 lymphocyte specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 2:1,261,957...1,295,891
Ensembl chr 2:1,262,081...1,295,891
JBrowse link
G LTF lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr13:29,413,886...29,445,751
Ensembl chr13:29,413,886...29,445,737
JBrowse link
G MASP2 mannan binding lectin serine peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 6:71,224,637...71,243,041
Ensembl chr 6:71,224,637...71,243,874
JBrowse link
G MIR155 microRNA mir-155 ISO miRNA:increased expression:colon
miRNA:decreased expression:feces
RGD PMID:29325325, PMID:29438285, PMID:29668922, PMID:30927737 RGD:21079443, RGD:21403682, RGD:24922207, RGD:24922213 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902
JBrowse link
G MIR31 microRNA mir-31 ISO miRNA:increased expression:colon RGD PMID:29438285 RGD:21403682 NCBI chr 1:201,198,732...201,198,809
Ensembl chr 1:201,198,732...201,198,809
JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:18837084 RGD:7207395 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,454,000
JBrowse link
G MMP9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,175,056...48,188,264
JBrowse link
G MPO myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826, PMID:22119283, PMID:24055189 NCBI chr12:34,557,031...34,570,091
Ensembl chr12:34,556,408...34,567,904
JBrowse link
G MST1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799 NCBI chr13:32,214,934...32,220,045
Ensembl chr13:32,214,937...32,219,902
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chr16:74,245,214...74,270,828
Ensembl chr16:74,245,224...74,270,802
JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming ISO mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chr 2:689,363...719,542 JBrowse link
G NKX2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405, PMID:18438406, PMID:20228799 NCBI chr14:110,720,384...110,724,002
Ensembl chr14:110,720,397...110,724,001
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 6:34,132,127...34,167,446
Ensembl chr 6:34,130,938...34,177,534
JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,259...22,429,621
JBrowse link
G PON1 paraoxonase 1 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,943,646...74,974,720
Ensembl chr 9:74,926,048...74,974,724
JBrowse link
G PON3 paraoxonase 3 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chr 9:74,983,040...75,017,947
Ensembl chr 9:74,991,277...75,017,942
JBrowse link
G PRDM1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:72,309,096...72,335,474
Ensembl chr 1:72,311,880...72,335,466
JBrowse link
G PSMG1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr13:202,762,509...202,775,601
Ensembl chr13:202,762,509...202,896,536
JBrowse link
G PTGER4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chr16:25,670,832...25,686,556
Ensembl chr16:25,670,862...25,686,552
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 1:262,456,106...262,482,159
Ensembl chr 1:262,456,155...262,483,035
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,013...127,858,884
JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr 6:96,769,862...96,847,136
Ensembl chr 6:96,770,251...96,847,133
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,092...47,074,725
JBrowse link
G RNF170 ring finger protein 170 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr17:11,777,942...11,817,920
Ensembl chr17:11,780,129...11,817,483
JBrowse link
G SELL selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr 4:81,306,363...81,325,296
Ensembl chr 4:81,306,373...81,326,778
JBrowse link
G SELP selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,406,203
JBrowse link
G SLC11A1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
DNA:transition, repeat:promoter:-237C>T (human)
CTD
RGD
PMID:11929588, PMID:16059695, PMID:18340647 RGD:5684939, RGD:5684968 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396
JBrowse link
G SLC26A3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chr 9:107,480,629...107,518,771
Ensembl chr 9:107,480,641...107,518,728
JBrowse link
G SPHK1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,948...5,120,119
JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18438405, PMID:20228799, PMID:22269120 RGD:6483020 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,993
JBrowse link
G SYNE1 spectrin repeat containing nuclear envelope protein 1 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr 1:13,715,644...14,201,711 JBrowse link
G THBD thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr17:30,219,870...30,223,499
Ensembl chr17:30,221,819...30,230,177
JBrowse link
G TNF tumor necrosis factor treatment ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:19617644, PMID:20452301, PMID:22119283, PMID:24812904, PMID:25204186, PMID:28120341 RGD:10450577, RGD:10450593, RGD:14975153 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
G TNFSF15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 1:255,328,731...255,349,508
Ensembl chr 1:255,325,936...255,349,456
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,908...117,511,226
JBrowse link
G VEGFA vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
G VIP vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chr 1:13,611,786...13,620,250
Ensembl chr 1:13,611,311...13,620,269
JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr13:26,036,610...26,073,168
Ensembl chr13:26,036,629...26,075,691
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 12649
    disease of anatomical entity 12188
      gastrointestinal system disease 4038
        intestinal disease 1373
          inflammatory bowel disease 292
            Crohn's disease + 93
            INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
            Inflammatory Bowel Disease 29 1
            Inflammatory Bowel Disease 30 0
            Neonatal Inflammatory Skin and Bowel Disease + 3
            colitis + 206
            inflammatory bowel disease 1 3
            inflammatory bowel disease 10 1
            inflammatory bowel disease 11 0
            inflammatory bowel disease 12 0
            inflammatory bowel disease 13 1
            inflammatory bowel disease 14 1
            inflammatory bowel disease 15 0
            inflammatory bowel disease 16 0
            inflammatory bowel disease 17 1
            inflammatory bowel disease 18 0
            inflammatory bowel disease 19 0
            inflammatory bowel disease 2 0
            inflammatory bowel disease 20 0
            inflammatory bowel disease 21 0
            inflammatory bowel disease 22 0
            inflammatory bowel disease 23 0
            inflammatory bowel disease 24 0
            inflammatory bowel disease 25 1
            inflammatory bowel disease 26 0
            inflammatory bowel disease 27 0
            inflammatory bowel disease 28 1
            inflammatory bowel disease 3 0
            inflammatory bowel disease 4 0
            inflammatory bowel disease 5 1
            inflammatory bowel disease 6 0
            inflammatory bowel disease 7 0
            inflammatory bowel disease 8 0
            inflammatory bowel disease 9 0
            ulcerative colitis + 102
Path 2
Term Annotations click to browse term
  disease 12649
    disease of anatomical entity 12188
      Immune & Inflammatory Diseases 2920
        Inflammation 1796
          gastroenteritis 366
            inflammatory bowel disease 292
              Crohn's disease + 93
              INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
              Inflammatory Bowel Disease 29 1
              Inflammatory Bowel Disease 30 0
              Neonatal Inflammatory Skin and Bowel Disease + 3
              colitis + 206
              inflammatory bowel disease 1 3
              inflammatory bowel disease 10 1
              inflammatory bowel disease 11 0
              inflammatory bowel disease 12 0
              inflammatory bowel disease 13 1
              inflammatory bowel disease 14 1
              inflammatory bowel disease 15 0
              inflammatory bowel disease 16 0
              inflammatory bowel disease 17 1
              inflammatory bowel disease 18 0
              inflammatory bowel disease 19 0
              inflammatory bowel disease 2 0
              inflammatory bowel disease 20 0
              inflammatory bowel disease 21 0
              inflammatory bowel disease 22 0
              inflammatory bowel disease 23 0
              inflammatory bowel disease 24 0
              inflammatory bowel disease 25 1
              inflammatory bowel disease 26 0
              inflammatory bowel disease 27 0
              inflammatory bowel disease 28 1
              inflammatory bowel disease 3 0
              inflammatory bowel disease 4 0
              inflammatory bowel disease 5 1
              inflammatory bowel disease 6 0
              inflammatory bowel disease 7 0
              inflammatory bowel disease 8 0
              inflammatory bowel disease 9 0
              ulcerative colitis + 102
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.