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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:inflammatory bowel disease
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Accession:DOID:0050589 term browser browse the term
Definition:An intestinal disease characterized by inflammation located in all parts of digestive tract. (DO)
Synonyms:exact_synonym: inflammatory bowel diseases
 narrow_synonym: CROHN DISEASE-ASSOCIATED GROWTH FAILURE, SUSCEPTIBILITY TO;   VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE;   regional enteritis;   ulcerative colitis
 related_synonym: Inflammatory bowel disease 1, susceptibility to
 primary_id: MESH:D015212
 xref: NCI:C3138;   OMIM:PS266600;   OMIM:PS614328
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
inflammatory bowel disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:18849144 RGD:5686819 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Ager advanced glycosylation end product-specific receptor ISO RGD PMID:21939913 RGD:6767556 NCBI chr17:34,597,460...34,600,937
Ensembl chr17:34,597,862...34,600,936
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO DNA:polymorphism: :p.M235T (human) RGD PMID:20717043 RGD:11039049 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Alpi alkaline phosphatase, intestinal ISO DNA:mutations:cds: RGD PMID:29567797 RGD:14367877 NCBI chr 1:87,098,002...87,101,606
Ensembl chr 1:87,098,002...87,101,606
JBrowse link
G Ang angiogenin, ribonuclease, RNase A family, 5 ISO protein:increased expression:serum RGD PMID:20629092 RGD:6892712 NCBI chr14:51,091,077...51,102,009
Ensembl chr14:51,091,150...51,102,009
JBrowse link
G Ano6 anoctamin 6 ISO associated with Spondylitis, Ankylosing;DNA:SNP: :rs17095830(human) RGD PMID:23308121 RGD:9684849 NCBI chr15:95,790,843...95,975,472
Ensembl chr15:95,790,843...95,974,751
JBrowse link
G Apc APC, WNT signaling pathway regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr18:34,220,297...34,322,190
Ensembl chr18:34,220,924...34,322,552
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr10:80,295,956...80,318,257
Ensembl chr10:80,295,977...80,318,263
JBrowse link
G Atg16l1 autophagy related 16-like 1 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chr 1:87,756,007...87,792,428
Ensembl chr 1:87,755,870...87,792,428
JBrowse link
G B2m beta-2 microglobulin ISO RGD PMID:20015205 RGD:6482693 NCBI chr 2:122,147,687...122,153,082
Ensembl chr 2:122,147,686...122,153,083
JBrowse link
G Card9 caspase recruitment domain family, member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 2:26,352,187...26,360,945
Ensembl chr 2:26,352,176...26,360,918
JBrowse link
G Cd40lg CD40 ligand IEA MouseDO NCBI chr  X:57,212,143...57,224,042
Ensembl chr  X:57,212,143...57,224,042
JBrowse link
G Cdh2 cadherin 2 IMP RGD PMID:7502046 RGD:734737 NCBI chr18:16,588,877...16,809,246
Ensembl chr18:16,588,877...16,809,246
JBrowse link
G Crp C-reactive protein, pentraxin-related ISO RGD PMID:22483567 RGD:6482301 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Cul2 cullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
JBrowse link
G Cyba cytochrome b-245, alpha polypeptide ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:3368442, PMID:9445163, PMID:10440830, PMID:19388116, PMID:25741868, PMID:30709874 NCBI chr 8:122,424,771...122,432,940
Ensembl chr 8:122,424,776...122,432,930
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO RGD PMID:14500559 RGD:5509042 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Fgf23 fibroblast growth factor 23 disease_progression ISO protein:increased expression:serum: RGD PMID:22551310 RGD:10044237 NCBI chr 6:127,072,902...127,082,296
Ensembl chr 6:127,072,902...127,081,408
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO DNA:deletion: : RGD PMID:21243434 RGD:5490537 NCBI chr 3:108,012,250...108,017,973
Ensembl chr 3:108,012,255...108,017,973
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 ISO DNA:deletion: : RGD PMID:21243434 RGD:5490537 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G Hp haptoglobin IEP RGD PMID:16775491 RGD:5147444 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Hpgd hydroxyprostaglandin dehydrogenase 15 (NAD) ISO protein, mRNA:increased expression: colonic mucosa: inflamed tissue only RGD PMID:16195422 RGD:5688766 NCBI chr 8:56,294,552...56,321,046
Ensembl chr 8:56,294,585...56,321,043
JBrowse link
G Hspa5 heat shock protein 5 ISO protein:increased expression RGD PMID:21864296 RGD:5685671 NCBI chr 2:34,772,090...34,776,529
Ensembl chr 2:34,771,970...34,777,547
JBrowse link
G Hspa8 heat shock protein 8 IEP RGD PMID:21135124 RGD:6218980 NCBI chr 9:40,801,276...40,805,202
Ensembl chr 9:40,800,984...40,810,087
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908, PMID:15638228 RGD:1625756 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma treatment IEP RGD PMID:31062617 RGD:14975125 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:20683203, PMID:12548059 RGD:5509948, RGD:5509968 NCBI chr 7:142,650,768...142,666,816
Ensembl chr 7:142,650,766...142,666,816
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO RGD PMID:15844718 RGD:1626117 NCBI chr11:7,206,086...7,215,498
Ensembl chr11:7,206,086...7,213,923
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta treatment IMP RGD PMID:22018461 RGD:7495770 NCBI chr 8:22,659,205...22,706,589
Ensembl chr 8:22,659,212...22,706,589
JBrowse link
G Il10 interleukin 10 no_association
treatment
IMP
ISO
IEP
IEA
ClinVar Annotator: match by term: Inflammatory bowel disease
DNA:SNP: :rs1800896 (human)
DNA:SNP: :rs3024505 (human)
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
MouseDO
PMID:23291587, PMID:25741868, PMID:27783946, PMID:28411859, PMID:28492532, PMID:30290665, PMID:22511846, PMID:27468578, PMID:27468578, PMID:31062617 RGD:7364854, RGD:11534627, RGD:11534627, RGD:14975125 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il10ra interleukin 10 receptor, alpha ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chr 9:45,253,837...45,269,149
Ensembl chr 9:45,253,837...45,269,149
JBrowse link
G Il10rb interleukin 10 receptor, beta ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chr16:91,406,157...91,425,834
Ensembl chr16:91,406,164...91,425,834
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 1:40,515,362...40,551,707
Ensembl chr 1:40,515,362...40,551,705
JBrowse link
G Il19 interleukin 19 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:25741868, PMID:28492532 NCBI chr 1:130,932,656...130,945,457
Ensembl chr 1:130,932,656...130,940,115
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO RGD PMID:12184521 RGD:10450573 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il2 interleukin 2 IEA MouseDO NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il21r interleukin 21 receptor ISO protein:increased expression:gut mucosa,leukocytes, mononuclear RGD PMID:19322899 RGD:6892935 NCBI chr 7:125,603,252...125,634,397
Ensembl chr 7:125,603,429...125,633,570
JBrowse link
G Il23r interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784, PMID:23291587, PMID:26192919 NCBI chr 6:67,422,932...67,491,855
Ensembl chr 6:67,422,932...67,491,855
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IEA MouseDO NCBI chr 2:11,642,792...11,693,194
Ensembl chr 2:11,642,807...11,693,193
JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:24491821 RGD:39938952 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il5 interleukin 5 susceptibility IEP RGD PMID:22018693 RGD:5687148 NCBI chr11:53,720,794...53,725,103
Ensembl chr11:53,720,794...53,725,106
JBrowse link
G Il6 interleukin 6 ISO ClinVar Annotator: match by synonym: Crohn disease-associated growth failure, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:9769329, PMID:10720087, PMID:11001912, PMID:11889177, PMID:12519862, PMID:12560873, PMID:12719374, PMID:15070960, PMID:15331795, PMID:15472205, PMID:16150725, PMID:16278864, PMID:17623760 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Inava innate immunity activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 1:136,213,522...136,234,293
Ensembl chr 1:136,213,531...136,234,264
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Itga4 integrin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 2:79,255,426...79,333,114
Ensembl chr 2:79,255,426...79,333,123
JBrowse link
G Itgal integrin alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 7:127,296,139...127,335,137
Ensembl chr 7:127,296,260...127,335,138
JBrowse link
G Itgb8 integrin beta 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr12:119,162,803...119,238,276
Ensembl chr12:119,158,022...119,238,802
JBrowse link
G Klkb1 kallikrein B, plasma 1 ISO RGD PMID:8625762 RGD:7327139 NCBI chr 8:45,266,688...45,294,835
Ensembl chr 8:45,266,689...45,294,859
JBrowse link
G Krt8 keratin 8 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:15090596, PMID:25741868 NCBI chr15:101,996,711...102,004,342
Ensembl chr15:101,996,698...102,004,482
JBrowse link
G Ltf lactotransferrin ISO RGD PMID:9791051 RGD:7243943 NCBI chr 9:111,019,292...111,042,766
Ensembl chr 9:111,019,271...111,042,767
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :1298A>C (human) RGD PMID:17111197 RGD:10449410 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Muc19 mucin 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr15:91,838,326...91,934,555
Ensembl chr15:91,838,326...91,934,555
JBrowse link
G Muc2 mucin 2 IEA MouseDO NCBI chr 7:141,690,340...141,754,691
Ensembl chr 7:141,690,340...141,754,693
JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IEA MouseDO NCBI chr13:52,967,209...52,982,878
Ensembl chr13:52,967,209...52,981,073
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO ClinVar Annotator: match by term: REGIONAL ENTERITIS
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Inflammatory bowel disease 1, susceptibility to
ClinVar
CTD
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12512038, PMID:12557156, PMID:12577202, PMID:14765395, PMID:15024686, PMID:15190267, PMID:15198989, PMID:15571588, PMID:15770725, PMID:15967635, PMID:18240302, PMID:18489434, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22684479, PMID:23102769, PMID:24033266, PMID:25741868, PMID:26070941, PMID:26192919, PMID:26500656, PMID:28450277, PMID:28492532 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO protein:increased expression:colon (rat) RGD PMID:21958875 RGD:5508753 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nox1 NADPH oxidase 1 ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:28492532, PMID:30709874 NCBI chr  X:134,086,421...134,137,711
Ensembl chr  X:134,086,421...134,221,956
JBrowse link
G Npsr1 neuropeptide S receptor 1 ISO RGD PMID:17854592 RGD:4891931 NCBI chr 9:24,097,912...24,317,590
Ensembl chr 9:24,097,996...24,316,398
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide ISO RGD PMID:11780721 RGD:6482691 NCBI chr15:79,995,865...80,024,614
Ensembl chr15:79,995,874...80,014,977
JBrowse link
G Plcg2 phospholipase C, gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 8:117,498,275...117,635,142
Ensembl chr 8:117,498,291...117,635,142
JBrowse link
G Pomc pro-opiomelanocortin-alpha IDA
IMP
protein:alternative form:large intestine epithelium: alphaMSH RGD PMID:9145424, PMID:21741932 RGD:5508804, RGD:5508805 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11820457 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24146755 NCBI chr 9:107,551,434...107,562,267
Ensembl chr 9:107,551,555...107,562,267
JBrowse link
G Runx3 runt related transcription factor 3 IEA MouseDO NCBI chr 4:135,120,645...135,177,990
Ensembl chr 4:135,120,652...135,177,990
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr 8:23,411,383...23,449,632
Ensembl chr 8:23,411,502...23,449,632
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chr 3:83,765,750...83,774,314
Ensembl chr 3:83,766,321...83,774,316
JBrowse link
G Slamf8 SLAM family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chr 1:172,581,377...172,590,873
Ensembl chr 1:172,581,758...172,590,568
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO DNA:polymorphisms: :1730G>A (human)
CTD Direct Evidence: marker/mechanism
DNA:point mutation:promoter:-237C>T (human)
CTD PMID:16597321, PMID:21128323, PMID:16059695 RGD:5684929, RGD:5684952 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Slc6a14 solute carrier family 6 (neurotransmitter transporter), member 14 ISO protein:decreased expression:epithelial cell, colon RGD PMID:17065219 RGD:1625272 NCBI chr  X:21,714,900...21,742,358
Ensembl chr  X:21,714,896...21,742,355
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IEA MouseDO NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Tcra T cell receptor alpha chain IEA MouseDO NCBI chr14:52,427,967...54,224,198 JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:29483653, PMID:28891831 RGD:14995457 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Themis thymocyte selection associated ISO DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chr10:28,668,360...28,883,820
Ensembl chr10:28,668,360...28,883,818
JBrowse link
G Tnf tumor necrosis factor treatment IMP
IEA
ISO
CTD Direct Evidence: marker/mechanism MouseDO
CTD
PMID:15086448, PMID:27793764, PMID:12184521 RGD:10450573 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chr 4:63,724,600...63,745,059
Ensembl chr 4:63,727,084...63,745,113
Ensembl chr 4:63,727,084...63,745,113
JBrowse link
G Tpmt thiopurine methyltransferase treatment ISO RGD PMID:17026564 RGD:11038726 NCBI chr13:47,021,987...47,043,338
Ensembl chr13:47,022,482...47,044,737
JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO protein:increased expression:serum,colon: RGD PMID:23642997 RGD:11079180 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17145956 NCBI chr10:23,894,688...23,905,344
Ensembl chr10:23,894,688...23,905,343
JBrowse link
G Xbp1 X-box binding protein 1 IEA MouseDO NCBI chr11:5,520,641...5,525,993
Ensembl chr11:5,520,659...5,525,893
JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 IEP protein:increased expression:small intestine, large intestine:extracellular space (mouse) RGD PMID:26401072 RGD:11555935 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964
JBrowse link
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 severity IMP Ace2 knockout
Ace2 inhibitor
RGD PMID:22837003, PMID:19517214 RGD:40818307, RGD:40818410 NCBI chr  X:164,139,342...164,188,418
Ensembl chr  X:164,139,332...164,188,420
JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:28740344 RGD:13782278 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:28740344 RGD:13782278 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23, alpha subunit p19 severity IMP RGD PMID:26455347 RGD:11097134 NCBI chr10:128,296,140...128,298,084
Ensembl chr10:128,296,139...128,298,752
JBrowse link
G Il33 interleukin 33 treatment
severity
IEP
IMP
RGD PMID:32156806, PMID:32156806 RGD:40400894, RGD:40400894 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr12:21,323,509...21,373,632
Ensembl chr12:21,323,509...21,373,632
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO
IMP
RGD PMID:17604368, PMID:21479819 RGD:5686754, RGD:5686898 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adk adenosine kinase IMP RGD PMID:11123368 RGD:6482664 NCBI chr14:21,052,574...21,448,569
Ensembl chr14:21,052,574...21,448,569
JBrowse link
G Adrb3 adrenergic receptor, beta 3 ISO mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Ahr aryl-hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chr12:35,497,979...35,534,989
Ensembl chr12:35,497,974...35,535,038
JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chr 6:116,410,071...116,461,178
Ensembl chr 6:116,410,077...116,461,178
JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chr19:20,373,434...20,390,671
Ensembl chr19:20,373,428...20,390,944
JBrowse link
G Apln apelin IEP RGD PMID:17391779 RGD:1626177 NCBI chr  X:48,025,146...48,034,853
Ensembl chr  X:48,025,146...48,034,853
JBrowse link
G Apoa4 apolipoprotein A-IV ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459
JBrowse link
G Aqp7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
JBrowse link
G Arg1 arginase, liver severity ISO RGD PMID:28423665 RGD:39939041 NCBI chr10:24,915,207...24,927,470
Ensembl chr10:24,915,221...24,927,484
JBrowse link
G Arrb1 arrestin, beta 1 ISO protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chr 7:99,535,147...99,606,772
Ensembl chr 7:99,535,466...99,606,771
JBrowse link
G Atp5d ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit treatment ISO RGD PMID:23840258 RGD:13792680 NCBI chr10:80,138,698...80,145,828
Ensembl chr10:80,138,632...80,145,818
JBrowse link
G Bdnf brain derived neurotrophic factor IEP protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:22361727 RGD:7242194 NCBI chr13:38,345,716...38,500,314
Ensembl chr13:38,345,107...38,500,302
JBrowse link
G Cat catalase ISO RGD PMID:21463646 RGD:5130869 NCBI chr 2:103,453,904...103,485,153
Ensembl chr 2:103,453,849...103,485,160
JBrowse link
G Cckbr cholecystokinin B receptor ISO RGD PMID:15102523 RGD:2311333 NCBI chr 7:105,425,676...105,436,339
Ensembl chr 7:105,425,731...105,470,898
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO RGD PMID:18690297 RGD:2307009 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccr1 chemokine (C-C motif) receptor 1 ISO RGD PMID:16399111 RGD:2307162 NCBI chr 9:123,962,126...123,968,692
Ensembl chr 9:123,962,124...123,968,692
JBrowse link
G Cd36 CD36 molecule IMP RGD PMID:19117124 RGD:6893503 NCBI chr 5:17,781,690...17,888,959
Ensembl chr 5:17,781,690...17,888,801
JBrowse link
G Cd40 CD40 antigen ISO RGD PMID:15591506 RGD:5508169 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473, PMID:11053450, PMID:11479205, PMID:11719428, PMID:11967536, PMID:12094328, PMID:12533788, PMID:12690581, PMID:14648717, PMID:14648718, PMID:14648719, PMID:15122511, PMID:15488637, PMID:15492928, PMID:15520402, PMID:16257342, PMID:16492927, PMID:16880452, PMID:17085682, PMID:18172190, PMID:19338683, PMID:19805189, PMID:21807500, PMID:21956126, PMID:22006311, PMID:22058428, PMID:22419737, PMID:22811390, PMID:22994785, PMID:23469205, PMID:24033266, PMID:24884479, PMID:25431674, PMID:25741868, PMID:26084796, PMID:26467025, PMID:26641009, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26884562, PMID:27083775, PMID:27153395, PMID:27269948, PMID:27433846, PMID:27751358, PMID:27798748, PMID:28125075, PMID:28135145, PMID:28195393, PMID:28492532, PMID:28503720, PMID:28514723, PMID:28727877, PMID:28734145, PMID:28779002, PMID:28802053, PMID:28874143, PMID:29351919, PMID:29489754, PMID:30311386 NCBI chr 5:110,839,800...110,874,140
Ensembl chr 5:110,839,979...110,874,145
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr19:44,073,334...44,107,505
Ensembl chr19:44,073,335...44,107,480
JBrowse link
G Ciita class II transactivator severity IEP
ISO
protein:increased expression:T cells:constitutive expression of transgene increases severity
ClinVar Annotator: match by term: Colitis
ClinVar PMID:25741868, PMID:28492532, PMID:17043423 RGD:5491188 NCBI chr16:10,480,014...10,531,064
Ensembl chr16:10,480,059...10,528,418
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086, PMID:21330446 RGD:5131259, RGD:5490987 NCBI chr 6:55,090,048...55,133,016
Ensembl chr 6:55,090,049...55,133,016
JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr14:63,122,462...63,145,923
Ensembl chr14:63,122,462...63,145,923
JBrowse link
G Ctsl cathepsin L IEP protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr13:64,361,890...64,370,772
Ensembl chr13:64,359,337...64,370,890
JBrowse link
G Ctss cathepsin S IEP protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chr 3:95,526,786...95,556,405
Ensembl chr 3:95,526,786...95,556,403
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 IEP associated with Helicobacter Infections;mRNA:decreased expression:colon (mouse, Helicobacter hepaticus) RGD PMID:17242461 RGD:38549339 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 ISO RGD PMID:14738862 RGD:7257706 NCBI chr 1:74,153,994...74,161,246
Ensembl chr 1:74,153,989...74,161,246
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dusp1 dual specificity phosphatase 1 severity IGI RGD PMID:22461024 RGD:7771532 NCBI chr17:26,505,591...26,508,472
Ensembl chr17:26,505,590...26,562,128
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO
IEP
mRNA:decreased expression:colon RGD PMID:21252046, PMID:21252046 RGD:5508810, RGD:5508810 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Fgf15 fibroblast growth factor 15 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 7:144,896,532...144,900,953
Ensembl chr 7:144,896,531...144,900,953
JBrowse link
G Flna filamin, alpha ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868, PMID:28492532 NCBI chr  X:74,223,461...74,249,854
Ensembl chr  X:74,223,461...74,249,820
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chr 2:62,474,530...62,483,653
Ensembl chr 2:62,474,530...62,483,650
JBrowse link
G Ghrl ghrelin ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chr 6:113,716,119...113,719,911
Ensembl chr 6:113,716,119...113,719,880
JBrowse link
G Gsta4 glutathione S-transferase, alpha 4 IEP protein:increased expression:colon, epithelial cell (mouse) RGD PMID:15309552 RGD:5687963 NCBI chr 9:78,191,966...78,209,349
Ensembl chr 9:78,182,774...78,209,349
JBrowse link
G H2-M2 histocompatibility 2, M region locus 2 ISO human gene in rat model; DNA:polymorphism:cds:HLA-B27 (human) RGD PMID:2257626 RGD:7387221 NCBI chr17:37,480,851...37,483,554
Ensembl chr17:37,480,851...37,483,552
JBrowse link
G H2-Q4 histocompatibility 2, Q region locus 4 ISO human gene in rat model; DNA:polymorphisms:cds:HLA-B27 (human) RGD PMID:2257626 RGD:7387221 NCBI chr17:35,379,617...35,384,674
Ensembl chr17:35,379,617...35,385,290
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chr11:46,739,822...46,779,578
Ensembl chr11:46,735,080...46,779,578
JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO protein:increased expression:colon:
CTD Direct Evidence: therapeutic
CTD PMID:16365149, PMID:21444764, PMID:22261574, PMID:21853095 RGD:7207796, RGD:10766442 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589
JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:22457771 RGD:11041866 NCBI chr 8:109,575,128...109,579,172
Ensembl chr 8:109,575,128...109,579,172
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Icos inducible T cell co-stimulator ISO protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chr 1:60,960,773...61,000,322
Ensembl chr 1:60,977,927...61,000,320
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Ikbkb inhibitor of kappaB kinase beta treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chr 8:22,659,205...22,706,589
Ensembl chr 8:22,659,212...22,706,589
JBrowse link
G Il10 interleukin 10 treatment ISO
IMP
CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:19238344, PMID:21807089, PMID:22119709, PMID:24314293, PMID:21949848, PMID:22461024, PMID:23771723 RGD:7349385, RGD:7771532, RGD:7365024 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il17a interleukin 17A IMP
ISO
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon
CTD PMID:24548422, PMID:14962796, PMID:20881082 RGD:4888509, RGD:4781448 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507, PMID:24548422, PMID:22969190 RGD:7204699 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 severity IMP RGD PMID:23172891 RGD:40400694 NCBI chr 1:40,404,864...40,465,418
Ensembl chr 1:40,429,570...40,465,415
JBrowse link
G Il33 interleukin 33 severity ISO
IDA
IEP
RGD PMID:28423665, PMID:23172891, PMID:23172891 RGD:39939041, RGD:40400694, RGD:40400694 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il4 interleukin 4 treatment IDA
ISO
CTD Direct Evidence: therapeutic CTD PMID:24314293, PMID:9389741 RGD:8142400 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il5 interleukin 5 IEP protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chr11:53,720,794...53,725,103
Ensembl chr11:53,720,794...53,725,106
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22410118, PMID:24548422 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgb2 integrin beta 2 IMP associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chr10:77,530,329...77,565,708
Ensembl chr10:77,530,252...77,565,708
JBrowse link
G Kdr kinase insert domain protein receptor ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Lct lactase ISO protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chr 1:128,284,756...128,328,318
Ensembl chr 1:128,284,756...128,328,318
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 IMP RGD PMID:21983832 RGD:5508401 NCBI chr15:91,672,791...91,816,124
Ensembl chr15:91,673,175...91,816,120
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chr10:79,664,559...79,668,542
Ensembl chr10:79,664,559...79,668,537
JBrowse link
G Mc1r melanocortin 1 receptor IAGP RGD PMID:16543288 RGD:5687320 NCBI chr 8:123,407,082...123,410,744
Ensembl chr 8:123,407,107...123,410,744
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) ISO CTD Direct Evidence: therapeutic CTD PMID:12105854, PMID:17324399 RGD:1641979 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Msh2 mutS homolog 2 ISO RGD PMID:23883737 RGD:10412318 NCBI chr17:87,672,532...87,723,713
Ensembl chr17:87,672,330...87,723,713
JBrowse link
G Muc2 mucin 2 treatment ISO
IGI
mRNA:decreased expression:colon
protein:decreased sulfation:descending colon
RGD PMID:19220658, PMID:21949848, PMID:23395625, PMID:12395902 RGD:2324675, RGD:7349385, RGD:7349360, RGD:7349356 NCBI chr 7:141,690,340...141,754,691
Ensembl chr 7:141,690,340...141,754,693
JBrowse link
G Muc3 mucin 3, intestinal treatment ISO mRNA:increased expression:ileum, colon RGD PMID:16964428, PMID:23395625 RGD:1625545, RGD:7349360 NCBI chr 5:137,134,924...137,166,048
Ensembl chr 5:137,134,922...137,149,322
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chr12:32,820,335...32,853,369
Ensembl chr12:32,819,545...32,853,349
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 IMP RGD PMID:20921147 RGD:5508755 NCBI chr 6:54,923,942...54,972,674
Ensembl chr 6:54,923,949...54,972,612
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO
IMP
mRNA:increased expression:colon RGD PMID:16891783, PMID:20921147, PMID:21471573 RGD:1600781, RGD:5508755, RGD:5508727 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Nos2 nitric oxide synthase 2, inducible ISO
IEP
mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:colon (mouse)
CTD PMID:8698225, PMID:17449036, PMID:16866779, PMID:21930116 RGD:4891411, RGD:5509045 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell ISO mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 ISO mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chr 3:87,778,244...87,795,242
Ensembl chr 3:87,778,244...87,795,162
JBrowse link
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chr13:58,806,472...59,133,970
Ensembl chr13:58,806,569...59,133,970
JBrowse link
G Pgf placental growth factor IMP RGD PMID:20142801 RGD:6483587 NCBI chr12:85,166,637...85,177,785
Ensembl chr12:85,166,635...85,177,790
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma IMP RGD PMID:21244371 RGD:6482682 NCBI chr12:32,173,397...32,208,677
Ensembl chr12:32,173,473...32,208,659
JBrowse link
G Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) IDA RGD PMID:17982090 RGD:6482729 NCBI chr 4:138,831,857...138,835,189
Ensembl chr 4:138,831,857...138,835,186
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility IDA RGD PMID:20650341 RGD:5509936 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha ISO RGD PMID:22126533 RGD:6484264 NCBI chr 5:51,454,249...52,115,853
Ensembl chr 5:51,454,250...51,567,726
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) IMP RGD PMID:20833794 RGD:6483551 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:11820457, PMID:17543437 RGD:2298659 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism
CTD PMID:23810507, PMID:18623154 RGD:2298776 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Retn resistin treatment ISO RGD PMID:22630819 RGD:7207222 NCBI chr 8:3,655,770...3,659,818
Ensembl chr 8:3,655,770...3,660,110
JBrowse link
G Sell selectin, lymphocyte ISO RGD PMID:18054560 RGD:5685703 NCBI chr 1:164,061,987...164,082,930
Ensembl chr 1:164,061,982...164,084,181
JBrowse link
G Selp selectin, platelet ISO protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chr 1:164,115,264...164,150,026
Ensembl chr 1:164,115,264...164,150,026
JBrowse link
G Selplg selectin, platelet (p-selectin) ligand IMP RGD PMID:22009715 RGD:6218987 NCBI chr 5:113,817,798...113,832,528
Ensembl chr 5:113,818,536...113,832,644
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103, PMID:24548422, PMID:24782617 NCBI chr10:63,319,005...63,339,035
Ensembl chr10:63,319,005...63,381,704
JBrowse link
G Sis sucrase isomaltase (alpha-glucosidase) ISO mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chr 3:72,888,557...72,967,863
Ensembl chr 3:72,888,557...72,967,863
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 IMP RGD PMID:19016783 RGD:5684975 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Src Rous sarcoma oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862
JBrowse link
G Tac1 tachykinin 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chr 6:82,402,003...82,560,104
Ensembl chr 6:82,402,334...82,560,104
JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:18715640, PMID:12490601 RGD:2304260, RGD:5147478 NCBI chr10:62,252,438...62,265,990
Ensembl chr10:62,252,438...62,265,990
JBrowse link
G Tff1 trefoil factor 1 ISO RGD PMID:8836141 RGD:625375 NCBI chr17:31,161,395...31,165,060
Ensembl chr17:31,161,395...31,165,277
JBrowse link
G Timp3 tissue inhibitor of metalloproteinase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chr10:86,300,412...86,349,505
Ensembl chr10:86,300,372...86,349,506
JBrowse link
G Tlr3 toll-like receptor 3 ISO mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chr 8:45,395,665...45,411,075
Ensembl chr 8:45,395,665...45,411,080
JBrowse link
G Tlr4 toll-like receptor 4 ISO
IMP
protein:increased expression:colon RGD PMID:19002562, PMID:19924809 RGD:2312573, RGD:7794773 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507, PMID:24548422 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tst thiosulfate sulfurtransferase, mitochondrial ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chr15:78,399,556...78,405,865
Ensembl chr15:78,399,556...78,405,907
JBrowse link
G Ucn urocortin ISO mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chr 5:31,137,989...31,138,895
Ensembl chr 5:31,138,063...31,138,829
JBrowse link
G Ucn2 urocortin 2 ISO mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chr 9:108,986,163...108,987,164
Ensembl chr 9:108,986,010...108,987,164
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link
G Vip vasoactive intestinal polypeptide IDA associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chr10:5,639,193...5,647,617
Ensembl chr10:5,639,218...5,647,617
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 IMP RGD PMID:21295288 RGD:5685384 NCBI chr12:116,077,420...116,148,637
Ensembl chr12:116,077,726...116,146,261
JBrowse link
Crohn's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:21829567, PMID:16432373 RGD:5686726 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) ISO ClinVar Annotator: match by term: Crohn disease, association with ClinVar PMID:9120024, PMID:9894356, PMID:13937884, PMID:15077204, PMID:17047091, PMID:20978123 NCBI chr 8:124,556,587...124,569,706
Ensembl chr 8:124,556,534...124,569,706
JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr11:70,241,457...70,255,380
Ensembl chr11:70,241,457...70,255,353
JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chr 1:87,098,002...87,101,606
Ensembl chr 1:87,098,002...87,101,606
JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:48,025,146...48,034,853
Ensembl chr  X:48,025,146...48,034,853
JBrowse link
G Apoa4 apolipoprotein A-IV severity ISO protein:decreased expression:blood plasma (human) RGD PMID:17206692 RGD:5685660 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459
JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
JBrowse link
G Atg16l1 autophagy related 16-like 1 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756, PMID:18438406 NCBI chr 1:87,756,007...87,792,428
Ensembl chr 1:87,755,870...87,792,428
JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108
JBrowse link
G Bglap bone gamma carboxyglutamate protein ISO mRNA:decreased expression:bone
protein:undercarboxylated:serum
RGD PMID:22535626, PMID:21482072 RGD:6483321, RGD:6483546 NCBI chr 3:88,383,495...88,384,466
Ensembl chr 3:88,383,501...88,384,464
JBrowse link
G Bpi bactericidal permeablility increasing protein ISO RGD PMID:15758620 RGD:1580079 NCBI chr 2:158,258,063...158,284,533
Ensembl chr 2:158,258,094...158,284,531
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr18:9,312,304...9,450,154
Ensembl chr18:9,312,304...9,450,154
JBrowse link
G Cd40 CD40 antigen susceptibility ISO protein:increased expression:intestine, epithelial cell
DNA:SNP:5' utr:c.-1C>T (rs1883832) (human)
RGD PMID:20133813, PMID:20634952 RGD:5490590, RGD:5490971 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cibar2 CBY1 interacting BAR domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr 8:120,166,397...120,177,486
Ensembl chr 8:120,166,397...120,177,466
JBrowse link
G Cldn1 claudin 1 ISO RGD PMID:21748286 RGD:11341809 NCBI chr16:26,356,645...26,371,839
Ensembl chr16:26,356,642...26,371,841
JBrowse link
G Crp C-reactive protein, pentraxin-related severity ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
CTD PMID:11339241, PMID:22421709 RGD:6482309 NCBI chr 1:172,698,056...172,699,966
Ensembl chr 1:172,698,055...172,833,031
JBrowse link
G Dennd1b DENN/MADD domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 1:138,963,709...139,176,043
Ensembl chr 1:138,963,435...139,178,960
JBrowse link
G Dnmt3a DNA methyltransferase 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr12:3,801,559...3,914,443
Ensembl chr12:3,806,007...3,914,443
JBrowse link
G Efs embryonal Fyn-associated substrate IEA MouseDO NCBI chr14:54,916,543...54,926,788
Ensembl chr14:54,916,535...54,926,126
JBrowse link
G Esr2 estrogen receptor 2 (beta) disease_progression ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G F13a1 coagulation factor XIII, A1 subunit ISO associated with Fistula;protein:decreased activity:plasma: RGD PMID:7611208 RGD:10450739 NCBI chr13:36,867,178...37,050,244
Ensembl chr13:36,867,178...37,050,244
JBrowse link
G F2 coagulation factor II ISO RGD PMID:21593018 RGD:5147754 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III susceptibility ISO DNA:polymorphism: :p.A519G (human) RGD PMID:20848524 RGD:5147918 NCBI chr 1:171,051,169...171,065,915
Ensembl chr 1:171,051,174...171,064,935
JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV treatment ISO DNA:SNP:exon:p.F158V (rs396991) (human) RGD PMID:14987319 RGD:1304543 NCBI chr 1:171,018,926...171,029,761
Ensembl chr 1:171,018,920...171,029,761
JBrowse link
G Fga fibrinogen alpha chain ISO RGD PMID:19683480 RGD:5688758 NCBI chr 3:83,026,153...83,033,627
Ensembl chr 3:83,026,076...83,033,627
JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr 1:71,585,473...71,653,280
Ensembl chr 1:71,585,520...71,653,200
JBrowse link
G Fpr2 formyl peptide receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21659618 NCBI chr17:17,887,824...17,893,952
Ensembl chr17:17,887,824...17,893,952
JBrowse link
G Fut2 fucosyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 7:45,648,591...45,666,394
Ensembl chr 7:45,648,591...45,666,394
JBrowse link
G Gc vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr 5:89,417,511...89,457,898
Ensembl chr 5:89,417,522...89,457,898
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23566200 NCBI chr 1:74,278,600...74,279,589
Ensembl chr 1:74,278,550...74,279,624
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 ISO RGD PMID:26604430 RGD:11538341 NCBI chr 3:108,012,250...108,017,973
Ensembl chr 3:108,012,255...108,017,973
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649 RGD:5490554 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO RGD PMID:29358886 RGD:14974239 NCBI chr17:34,263,227...34,269,418
Ensembl chr17:34,257,689...34,269,419
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25559196 NCBI chr17:34,305,867...34,316,674
Ensembl chr17:34,305,867...34,316,674
JBrowse link
G H2-Pa histocompatibility 2, P region alpha locus ISO RGD PMID:12073072 RGD:6480648 NCBI chr17:34,084,613...34,085,852
Ensembl chr17:34,084,601...34,085,823
JBrowse link
G Hfe homeostatic iron regulator treatment ISO DNA:SNP: :rs2071303 (human) RGD PMID:27115882 RGD:14701051 NCBI chr13:23,702,034...23,710,854
Ensembl chr13:23,702,034...23,710,854
JBrowse link
G Hspa1l heat shock protein 1-like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chr17:34,972,703...34,979,228
Ensembl chr17:34,972,703...34,979,285
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:15638228 RGD:1625756 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567, PMID:28070144 RGD:14974261 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il10 interleukin 10 treatment ISO
IMP
CTD Direct Evidence: marker/mechanism CTD PMID:21102463, PMID:11113068, PMID:29899181 RGD:11049181, RGD:14975133 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il12b interleukin 12b ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il21r interleukin 21 receptor ISO DNA:altered methylation: : RGD PMID:22021194 RGD:6482789 NCBI chr 7:125,603,252...125,634,397
Ensembl chr 7:125,603,429...125,633,570
JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO DNA:SNPs:multiple:
CTD Direct Evidence: marker/mechanism
CTD PMID:17435756, PMID:18438406, PMID:17068223 RGD:8549568 NCBI chr 6:67,422,932...67,491,855
Ensembl chr 6:67,422,932...67,491,855
JBrowse link
G Il2ra interleukin 2 receptor, alpha chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 2:11,642,792...11,693,194
Ensembl chr 2:11,642,807...11,693,193
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD
OMIM
PMID:10700533, PMID:21829567 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438406, PMID:19165925, PMID:21278745 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human) RGD PMID:22269120 RGD:6483020 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Kdr kinase insert domain protein receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr 6:29,060,221...29,073,876
Ensembl chr 6:29,060,220...29,073,877
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 ISO DNA:point mutation: :p.T2397M (rs3761863) (human) RGD PMID:21983832 RGD:5508401 NCBI chr15:91,672,791...91,816,124
Ensembl chr15:91,673,175...91,816,120
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO RGD PMID:11703369 RGD:2311550 NCBI chr10:79,664,559...79,668,542
Ensembl chr10:79,664,559...79,668,537
JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 susceptibility ISO DNA:polymorphisms:cds: RGD PMID:21702710 RGD:12910842 NCBI chr19:30,232,906...30,239,687
Ensembl chr19:30,232,942...30,239,687
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:feces RGD PMID:30927737, PMID:29668922, PMID:29325325 RGD:21079443, RGD:24922213, RGD:24922207 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 ISO RGD PMID:21364546 RGD:6483536 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mst1 macrophage stimulating 1 (hepatocyte growth factor-like) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 9:108,080,409...108,085,027
Ensembl chr 9:108,080,436...108,085,003
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28002332 NCBI chr 4:148,039,077...148,059,562
Ensembl chr 4:148,039,077...148,059,551
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr15:78,244,164...78,262,582
Ensembl chr15:78,244,801...78,262,580
JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438405, PMID:18438406 NCBI chr19:43,612,325...43,615,892
Ensembl chr19:43,612,325...43,615,892
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19098911 NCBI chr11:59,541,569...59,566,955
Ensembl chr11:59,541,568...59,566,956
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 susceptibility
no_association
ISO DNA:frameshift mutation, missense mutations
ClinVar Annotator: match by term: Inflammatory bowel disease 1
ClinVar Annotator: match by term: Enteritis, Granulomatous
ClinVar Annotator: match by term: Crohn disease
ClinVar Annotator: match by term: REGIONAL ENTERITIS
ClinVar Annotator: match by term: Crohn's disease
CTD Direct Evidence: marker/mechanism
DNA:missense mutations, frameshift mutation: :p.R702W, p.G908R, 3020_3021insC (human)
DNA:missense mutations: :multiple (human)
ClinVar
OMIM
CTD
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11528384, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12115249, PMID:12512038, PMID:12557156, PMID:12577202, PMID:12626759, PMID:12630966, PMID:14508222, PMID:14765395, PMID:15024686, PMID:15044951, PMID:15190267, PMID:15198989, PMID:15320482, PMID:15459013, PMID:15571588, PMID:15712650, PMID:15770725, PMID:15967635, PMID:16278823, PMID:16485124, PMID:17435756, PMID:17568627, PMID:18056399, PMID:18240302, PMID:18371140, PMID:18419343, PMID:18438406, PMID:18489434, PMID:18507017, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20032092, PMID:20230816, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22319155, PMID:22684479, PMID:22926499, PMID:22942351, PMID:23102769, PMID:23334666, PMID:24033266, PMID:24391456, PMID:24583628, PMID:24803813, PMID:24960071, PMID:25741868, PMID:26070941, PMID:26164256, PMID:26316104, PMID:26500656, PMID:27306066, PMID:28492532, PMID:28814775, PMID:11385576, PMID:21155887, PMID:21983784 RGD:1600778, RGD:5508730, RGD:5508719 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr10:89,454,234...89,533,645
Ensembl chr10:89,454,234...89,533,585
JBrowse link
G Ocln occludin ISO RGD PMID:21748286 RGD:11341809 NCBI chr13:100,496,504...100,552,718
Ensembl chr13:100,496,507...100,552,718
JBrowse link
G Pgf placental growth factor ISO protein:increased expression:serum RGD PMID:17980128 RGD:6483592 NCBI chr12:85,166,637...85,177,785
Ensembl chr12:85,166,635...85,177,790
JBrowse link
G Phox2b paired-like homeobox 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chr 5:67,094,397...67,099,126
Ensembl chr 5:67,094,399...67,099,301
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing IEA MouseDO NCBI chr 1:65,186,640...65,278,696
Ensembl chr 1:65,186,683...65,278,695
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:21114432 RGD:6483800 NCBI chr 7:24,460,937...24,475,970
Ensembl chr 7:24,462,484...24,475,968
JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:terminal ileum (human) RGD PMID:17664137 RGD:5509924 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:terminal ileum (human) RGD PMID:17664137 RGD:5509924 NCBI chr 6:5,216,256...5,256,285
Ensembl chr 6:5,220,852...5,256,286
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr15:85,734,910...85,806,851
Ensembl chr15:85,734,983...85,802,819
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Prf1 perforin 1 (pore forming protein) ISO DNA:hypermethylation RGD PMID:22021194 RGD:6482789 NCBI chr10:61,297,751...61,304,684
Ensembl chr10:61,297,833...61,304,680
JBrowse link
G Prkcq protein kinase C, theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chr 2:11,171,905...11,301,226
Ensembl chr 2:11,172,108...11,301,222
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:colon RGD PMID:21763290 RGD:5508200 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261 NCBI chr18:67,665,501...67,724,632
Ensembl chr18:67,665,511...67,724,595
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) ISO DNA:SNP:cds:rs2476601 (human) RGD PMID:18587394 RGD:6484668 NCBI chr 3:103,856,575...103,912,252
Ensembl chr 3:103,859,795...103,912,247
JBrowse link
G Sell selectin, lymphocyte ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr 1:164,061,987...164,082,930
Ensembl chr 1:164,061,982...164,084,181
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 no_association ISO DNA:repeat, polymorphisms:promoter, intron:p.D543N (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
DNA:point mutation:promoter:-237C>T (human)
DNA:polymorphism: :823C>T (human)
DNA:polymorphisms:promoter (human)
DNA:insertion/deletion:3' utr (human)
CTD PMID:16059695, PMID:18454481, PMID:11929588, PMID:15757519, PMID:16059695, PMID:17131479, PMID:17385031, PMID:18340647 RGD:5684938, RGD:5684968, RGD:5684956, RGD:5684952, RGD:5684942, RGD:5684941, RGD:5684939 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 susceptibility ISO DNA:snp, haplotype:promoter:g.-207G>C (human) RGD PMID:15107849 RGD:1580609 NCBI chr11:53,864,542...53,891,796
Ensembl chr11:53,864,542...53,891,660
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 9:63,646,766...63,757,994
Ensembl chr 9:63,646,767...63,757,994
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
DNA:SNPs: :rs744166, rs3816769 (human)
RGD PMID:22269120, PMID:20109474 RGD:6483020, RGD:6483027 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Tagap T cell activation Rho GTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr17:7,926,000...7,934,897
Ensembl chr17:7,926,000...7,934,897
JBrowse link
G Tcf7 transcription factor 7, T cell specific ISO CTD Direct Evidence: marker/mechanism CTD PMID:24994854 NCBI chr11:52,246,527...52,283,383
Ensembl chr11:52,252,371...52,283,331
JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr 2:148,404,471...148,408,188
Ensembl chr 2:148,404,466...148,408,188
JBrowse link
G Tlr4 toll-like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17914947 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
G Tlr9 toll-like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15236225, PMID:17914947 NCBI chr 9:106,222,598...106,226,876
Ensembl chr 9:106,222,598...106,226,883
JBrowse link
G Tnf tumor necrosis factor treatment ISO protein:increased expression:intestine mucosa
CTD Direct Evidence: marker/mechanism
CTD PMID:10700533, PMID:21829567, PMID:21359923, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a treatment ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923 RGD:5130893 NCBI chr 4:145,212,368...145,246,870
Ensembl chr 4:145,213,463...145,246,870
JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chr 9:21,104,068...21,131,393
Ensembl chr 9:21,104,068...21,131,243
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 ISO DNA:polymorphism:promoter RGD PMID:22398043 RGD:6482850 NCBI chr 1:88,211,959...88,220,002
Ensembl chr 1:88,211,959...88,218,997
JBrowse link
G Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor ISO GAD PMID:15118671 RGD:1331525 NCBI chr15:97,854,427...97,908,296
Ensembl chr15:97,854,425...97,910,630
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma, large intestine mucosa RGD PMID:19013462 RGD:5684406 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr 9:121,642,716...121,672,954
Ensembl chr 9:121,642,716...121,672,954
JBrowse link
G Vtn vitronectin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chr11:78,499,120...78,502,325
Ensembl chr11:78,499,091...78,502,324
JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 treatment IMP RGD PMID:24239644, PMID:17342403 RGD:40400720, RGD:40400748 NCBI chr11:105,967,948...105,989,964
Ensembl chr11:105,967,945...105,989,964
JBrowse link
G Acer3 alkaline ceramidase 3 severity IEP
IMP
mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296, PMID:26938296 RGD:35673322, RGD:35673322 NCBI chr 7:98,213,808...98,321,208
Ensembl chr 7:98,206,389...98,321,208
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 treatment ISO RGD PMID:11884025 RGD:632022 NCBI chr12:21,323,509...21,373,632
Ensembl chr12:21,323,509...21,373,632
JBrowse link
G Adrb3 adrenergic receptor, beta 3 no_association ISO mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chr 8:27,225,776...27,230,845
Ensembl chr 8:27,225,776...27,250,616
JBrowse link
G Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 treatment ISO RGD PMID:25689466 RGD:13703055 NCBI chr18:77,773,768...77,782,869
Ensembl chr18:77,773,729...77,782,869
JBrowse link
G Cd209b CD209b antigen IMP RGD PMID:20130211 RGD:39938984 NCBI chr 8:3,917,655...3,926,841
Ensembl chr 8:3,917,655...3,926,844
JBrowse link
G Cd209d CD209d antigen treatment IMP RGD PMID:20130211 RGD:39938984 NCBI chr 8:3,871,824...3,878,548
Ensembl chr 8:3,871,824...3,878,555
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chr11:98,700,183...98,703,631
Ensembl chr11:98,701,263...98,703,629
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 treatment ISO RGD PMID:29655167 RGD:39939058 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Ereg epiregulin IEP protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chr 5:91,074,617...91,093,649
Ensembl chr 5:91,074,622...91,093,646
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO RGD PMID:22368862 RGD:10054108 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Foxp3 forkhead box P3 treatment IEP
ISO
mRNA:increased expression:mucosa:
protein:increased expression:colon:
RGD PMID:26925602, PMID:28733028, PMID:27498708, PMID:17229795 RGD:38455994, RGD:38549362, RGD:14975101, RGD:38455995 NCBI chr  X:7,579,676...7,595,243
Ensembl chr  X:7,573,644...7,595,245
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chr 7:30,942,368...30,944,029
Ensembl chr 7:30,942,368...30,944,032
JBrowse link
G Hsf1 heat shock factor 1 ISO protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chr15:76,477,362...76,501,155
Ensembl chr15:76,477,422...76,501,913
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10092309 RGD:11522714 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma ISO
IEP
protein:increased expression:plasma: RGD PMID:15030379, PMID:27498708 RGD:10755756, RGD:14975101 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Il10 interleukin 10 treatment IMP
ISO
associated with Helicobacter Infections RGD PMID:16982822, PMID:27815529, PMID:25727887 RGD:11049170, RGD:14975260, RGD:11049485 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il1b interleukin 1 beta treatment IEP RGD PMID:31175857 RGD:14975282 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:16630696 RGD:8662978 NCBI chr 3:37,120,713...37,125,954
Ensembl chr 3:37,120,523...37,125,959
JBrowse link
G Il23a interleukin 23, alpha subunit p19 severity IEP mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chr10:128,296,140...128,298,084
Ensembl chr10:128,296,139...128,298,752
JBrowse link
G Il33 interleukin 33 severity
treatment
IEP
IDA
RGD PMID:25112700, PMID:28423665 RGD:39938951, RGD:39939041 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il6 interleukin 6 treatment ISO
IDA
RGD PMID:16630696, PMID:27096537, PMID:16133010 RGD:8662978, RGD:11062146, RGD:11062139 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itga2 integrin alpha 2 treatment IMP RGD PMID:16534417 RGD:11530069 NCBI chr13:114,833,081...114,932,100
Ensembl chr13:114,833,081...114,932,100
JBrowse link
G Itga4 integrin alpha 4 ISO protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chr 2:79,255,426...79,333,114
Ensembl chr 2:79,255,426...79,333,123
JBrowse link
G Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 ISO mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chr14:23,292,288...24,005,110
Ensembl chr14:23,289,431...24,014,491
JBrowse link
G Kdr kinase insert domain protein receptor IEP protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Kl klotho IEP mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chr 5:150,952,607...150,993,817
Ensembl chr 5:150,952,607...150,993,817
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:27028006 RGD:13800882 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29037916 RGD:13800567 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) severity IDA RGD PMID:15807847 RGD:36947390 NCBI chr10:75,859,353...75,860,277
Ensembl chr10:75,859,353...75,860,240
JBrowse link
G Mir155 microRNA 155 treatment IEP
ISO
IMP
associated with Helicobacter Infections RGD PMID:30927737, PMID:28461115, PMID:28752563, PMID:30253332, PMID:21880981, PMID:28246471 RGD:21079443, RGD:25314295, RGD:24922208, RGD:21081536, RGD:21079473, RGD:21079463 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mydgf myeloid derived growth factor severity
treatment
IMP
IDA
associated with hymenolepiasis RGD PMID:27055194, PMID:19118508, PMID:20490892 RGD:11532263, RGD:39456129, RGD:39456118 NCBI chr17:56,176,541...56,183,920
Ensembl chr17:56,175,744...56,183,920
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 treatment ISO RGD PMID:22350949 RGD:10412739 NCBI chr 2:75,675,513...75,704,663
Ensembl chr 2:75,675,513...75,704,641
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha treatment ISO RGD PMID:21642017 RGD:10413866 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Npy neuropeptide Y treatment ISO RGD PMID:20533056 RGD:10448943 NCBI chr 6:49,822,710...49,829,507
Ensembl chr 6:49,822,710...49,829,507
JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr 5:75,151,322...75,198,206
Ensembl chr 5:75,152,292...75,198,215
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chr18:61,045,127...61,085,067
Ensembl chr18:61,045,150...61,085,061
JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked IEP mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chr  X:157,162,075...157,415,286
Ensembl chr  X:157,162,075...157,415,312
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma susceptibility IMP RGD PMID:20347874 RGD:38599183 NCBI chr12:32,173,397...32,208,677
Ensembl chr12:32,173,473...32,208,659
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) treatment ISO RGD PMID:12100473 RGD:727388 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 IMP RGD PMID:19116231 RGD:5684934 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Smad4 SMAD family member 4 susceptibility IMP RGD PMID:23090737 RGD:12880038 NCBI chr18:73,634,790...73,703,791
Ensembl chr18:73,639,009...73,703,780
JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chr 6:125,349,723...125,362,483
Ensembl chr 6:125,349,362...125,362,484
JBrowse link
G Vegfa vascular endothelial growth factor A IEP protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
ileitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 chemokine (C-C motif) receptor 2 IMP RGD PMID:22848538 RGD:8661712 NCBI chr 9:124,101,918...124,109,140
Ensembl chr 9:124,101,950...124,113,557
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 IMP RGD PMID:21945903 RGD:6892917 NCBI chr 9:124,017,825...124,031,692
Ensembl chr 9:124,021,972...124,031,689
JBrowse link
G Cd80 CD80 antigen IEP RGD PMID:22068168 RGD:6902902 NCBI chr16:38,457,430...38,495,958
Ensembl chr16:38,455,561...38,496,335
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il17a interleukin 17A ISO mRNA:increased expression:ileum RGD PMID:18536735 RGD:4837793 NCBI chr 1:20,730,905...20,734,496
Ensembl chr 1:20,730,905...20,734,496
JBrowse link
G Itgam integrin alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:10647630 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Tlr2 toll-like receptor 2 ISO RGD PMID:18266231 RGD:2312714 NCBI chr 3:83,836,272...83,841,824
Ensembl chr 3:83,836,272...83,841,767
JBrowse link
G Tlr4 toll-like receptor 4 IMP
ISO
RGD PMID:17255219, PMID:18266231 RGD:7241089, RGD:2312714 NCBI chr 4:66,827,551...66,846,581
Ensembl chr 4:66,827,584...66,930,284
JBrowse link
inflammatory bowel disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1l heat shock protein 1-like ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:28126021 NCBI chr17:34,972,703...34,979,228
Ensembl chr17:34,972,703...34,979,285
JBrowse link
G Il6 interleukin 6 ISS OMIM:266600 MouseDO NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEA
ISO
ISS
OMIM:266600
ClinVar Annotator: match by term: Inflammatory bowel disease 1
MouseDO
ClinVar
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12115249, PMID:12512038, PMID:12557156, PMID:12577202, PMID:12626759, PMID:12630966, PMID:14508222, PMID:14765395, PMID:15024686, PMID:15044951, PMID:15190267, PMID:15198989, PMID:15320482, PMID:15459013, PMID:15571588, PMID:15712650, PMID:15770725, PMID:15967635, PMID:16278823, PMID:16485124, PMID:18056399, PMID:18240302, PMID:18419343, PMID:18489434, PMID:18507017, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20032092, PMID:20230816, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22319155, PMID:22684479, PMID:22926499, PMID:22942351, PMID:23102769, PMID:24033266, PMID:24391456, PMID:24583628, PMID:24803813, PMID:24960071, PMID:25741868, PMID:26070941, PMID:26164256, PMID:26316104, PMID:26500656, PMID:27306066, PMID:28492532, PMID:28814775 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Prkcq protein kinase C, theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chr 2:11,171,905...11,301,226
Ensembl chr 2:11,172,108...11,301,222
JBrowse link
inflammatory bowel disease 10 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg16l1 autophagy related 16-like 1 (S. cerevisiae) ISO
IEA
OMIM:611081
ClinVar Annotator: match by term: Inflammatory bowel disease 10, susceptibility to
OMIM
MouseDO
ClinVar
PMID:17200669, PMID:17435756, PMID:18438405, PMID:18852889, PMID:19337756, PMID:24553140, PMID:27273576 NCBI chr 1:87,756,007...87,792,428
Ensembl chr 1:87,755,870...87,792,428
JBrowse link
inflammatory bowel disease 12 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 IEA OMIM:612241 MouseDO NCBI chr 9:107,614,125...107,635,391
Ensembl chr 9:107,614,125...107,635,367
JBrowse link
inflammatory bowel disease 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A ISO
IEA
ClinVar Annotator: match by term: Inflammatory bowel disease 13
OMIM:612244
OMIM
ClinVar
MouseDO
PMID:14610718, PMID:16321621, PMID:19891551, PMID:20707787, PMID:22992668, PMID:25012726 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
inflammatory bowel disease 14 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf5 interferon regulatory factor 5 ISO OMIM NCBI chr 6:29,526,130...29,541,869
Ensembl chr 6:29,526,625...29,541,871
JBrowse link
inflammatory bowel disease 16 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 IEA OMIM:612259 MouseDO NCBI chr 4:63,724,600...63,745,059
Ensembl chr 4:63,727,084...63,745,113
Ensembl chr 4:63,727,084...63,745,113
JBrowse link
inflammatory bowel disease 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23r interleukin 23 receptor ISO ClinVar Annotator: match by term: Inflammatory bowel disease 17, protection against OMIM
ClinVar
PMID:12023369, PMID:17068223, PMID:17447842, PMID:17587057, PMID:17786191, PMID:17804789, PMID:18438406, PMID:19122664, PMID:20228799 NCBI chr 6:67,422,932...67,491,855
Ensembl chr 6:67,422,932...67,491,855
JBrowse link
inflammatory bowel disease 19 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irgm1 immunity-related GTPase family M member 1 ISO ClinVar Annotator: match by OMIM:612278 OMIM
ClinVar
PMID:17554261, PMID:18985712, PMID:19174780, PMID:21278745 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
inflammatory bowel disease 25 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10rb interleukin 10 receptor, beta ISO ClinVar Annotator: match by OMIM:612567
ClinVar Annotator: match by term: Inflammatory bowel disease 25, autosomal recessive
ClinVar
OMIM
PMID:16757563, PMID:19890111, PMID:21519361, PMID:22549091, PMID:24033266, PMID:25373860, PMID:27336593, PMID:27699073, PMID:28492532, PMID:29248579, PMID:30365510 NCBI chr16:91,406,157...91,425,834
Ensembl chr16:91,406,164...91,425,834
JBrowse link
inflammatory bowel disease 28 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BC049352 cDNA sequence BC049352 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 28, autosomal recessive ClinVar NCBI chr 9:45,195,688...45,251,370
Ensembl chr 9:45,182,007...45,250,020
JBrowse link
G Il10ra interleukin 10 receptor, alpha ISO ClinVar Annotator: match by term: Inflammatory bowel disease 28, autosomal recessive
ClinVar Annotator: match by OMIM:613148
OMIM
ClinVar
PMID:19890111, PMID:21519361, PMID:22476154, PMID:22549091, PMID:23158016, PMID:24033266, PMID:24813381, PMID:25741868, PMID:26193622, PMID:26822028, PMID:27699570, PMID:28267044, PMID:28492532, PMID:28930861, PMID:29140941, PMID:29248579 NCBI chr 9:45,253,837...45,269,149
Ensembl chr 9:45,253,837...45,269,149
JBrowse link
Inflammatory Bowel Disease 29 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator ISO ClinVar Annotator: match by term: INFLAMMATORY BOWEL DISEASE 29 OMIM
ClinVar
PMID:21983784, PMID:25741868, PMID:29420262 NCBI chr 1:136,213,522...136,234,293
Ensembl chr 1:136,213,531...136,234,264
JBrowse link
inflammatory bowel disease 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 ISO ClinVar Annotator: match by null ClinVar PMID:15107849, PMID:16333318, PMID:17213842 NCBI chr11:53,864,542...53,891,796
Ensembl chr11:53,864,542...53,891,660
JBrowse link
INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor, beta 1 ISO ClinVar Annotator: match by term: INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY OMIM
ClinVar
PMID:25741868, PMID:29483653 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chr 5:137,061,504...137,072,272
Ensembl chr 5:137,061,504...137,072,268
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal 1 ClinVar
OMIM
PMID:22010916, PMID:28492532 NCBI chr12:21,323,509...21,373,632
Ensembl chr12:21,323,509...21,373,632
JBrowse link
G Iah1 isoamyl acetate-hydrolyzing esterase 1 homolog ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal 1 ClinVar PMID:28492532 NCBI chr12:21,316,362...21,323,607
Ensembl chr12:21,316,389...21,323,819
JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal, 2 ClinVar
OMIM
PMID:24691054 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
Pediatric Crohn's Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 ISO mRNA:increased expression:duodenum:non-inflamed tissue RGD PMID:16917230 RGD:5685614 NCBI chr 5:137,892,933...137,925,610
Ensembl chr 5:137,892,932...137,921,619
JBrowse link
G F2 coagulation factor II ISO RGD PMID:21287673 RGD:5147769 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:duodenal mucosa RGD PMID:27468194 RGD:25671466 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:11321389 RGD:7394742 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rn interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chr 5:8,567,091...8,748,575
Ensembl chr 5:8,660,077...8,748,575
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chr 7:119,760,883...119,784,896
Ensembl chr 7:119,760,923...119,787,513
JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chr 8:88,272,190...88,329,965
Ensembl chr 8:88,272,403...88,329,962
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chr16:23,146,536...23,157,968
Ensembl chr16:23,146,536...23,158,028
JBrowse link
G Adrb2 adrenergic receptor, beta 2 ISO protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chr18:62,177,713...62,179,981
Ensembl chr18:62,177,816...62,179,959
JBrowse link
G Alox12 arachidonate 12-lipoxygenase ISO protein:increased expression:large intestine epithelium RGD PMID:7679252 RGD:5509621 NCBI chr11:70,241,457...70,255,380
Ensembl chr11:70,241,457...70,255,353
JBrowse link
G Alpi alkaline phosphatase, intestinal ISO protein:decreased expression:colonic mucosa RGD PMID:22783049 RGD:14367879 NCBI chr 1:87,098,002...87,101,606
Ensembl chr 1:87,098,002...87,101,606
JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chr  X:48,025,146...48,034,853
Ensembl chr  X:48,025,146...48,034,853
JBrowse link
G Apoa4 apolipoprotein A-IV severity ISO DNA:missense mutation:cds:p.Q360H (human) RGD PMID:17206692 RGD:5685660 NCBI chr 9:46,240,844...46,243,458
Ensembl chr 9:46,240,696...46,243,459
JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chr 4:41,033,074...41,048,237
Ensembl chr 4:41,033,074...41,048,139
JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chr 1:74,236,490...74,268,209
Ensembl chr 1:74,236,084...74,268,209
JBrowse link
G Brinp3 bone morphogenetic protein/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chr 1:146,495,629...146,902,472
Ensembl chr 1:146,494,760...146,902,472
JBrowse link
G Btnl2 butyrophilin-like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chr17:34,354,789...34,369,492
Ensembl chr17:34,354,822...34,369,495
JBrowse link
G Card9 caspase recruitment domain family, member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 2:26,352,187...26,360,945
Ensembl chr 2:26,352,176...26,360,918
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Ccl20 chemokine (C-C motif) ligand 20 treatment ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769, PMID:21887805 RGD:7488892 NCBI chr 1:83,116,766...83,119,167
Ensembl chr 1:83,116,766...83,119,167
JBrowse link
G Ccl7 chemokine (C-C motif) ligand 7 ISO protein:increased expression:colon RGD PMID:10433925 RGD:6483784 NCBI chr11:82,045,712...82,047,525
Ensembl chr11:82,045,712...82,047,525
JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr18:9,312,304...9,450,154
Ensembl chr18:9,312,304...9,450,154
JBrowse link
G Ccr3 chemokine (C-C motif) receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chr 9:124,017,825...124,031,692
Ensembl chr 9:124,021,972...124,031,689
JBrowse link
G Ccr6 chemokine (C-C motif) receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chr17:8,236,041...8,258,519
Ensembl chr17:8,236,043...8,257,141
JBrowse link
G Cd40 CD40 antigen ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chr 2:165,055,614...165,071,654
Ensembl chr 2:165,055,627...165,072,948
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Cdh3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 8:106,510,852...106,556,911
Ensembl chr 8:106,510,891...106,557,297
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 ISO Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chr10:77,052,178...77,166,530
Ensembl chr10:77,052,178...77,166,548
JBrowse link
G Col1a1 collagen, type I, alpha 1 ISO RGD PMID:17939044 RGD:5688304 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12133438, PMID:15955209 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcr1 chemokine (C-X-C motif) receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:74,191,785...74,194,708
Ensembl chr 1:74,191,785...74,194,631
JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:74,153,994...74,161,246
Ensembl chr 1:74,153,989...74,161,246
JBrowse link
G Cxcr3 chemokine (C-X-C motif) receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr  X:101,731,535...101,734,147
Ensembl chr  X:101,731,535...101,734,269
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells (human) RGD PMID:21087446 RGD:6480657 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Dap death-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr15:31,224,385...31,274,338
Ensembl chr15:31,224,314...31,274,341
JBrowse link
G Defa32 defensin, alpha, 32 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 8:21,529,030...21,530,012
Ensembl chr 8:21,529,032...21,530,012
JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chr 3:95,734,147...95,739,876
Ensembl chr 3:95,734,147...95,739,569
JBrowse link
G Esr2 estrogen receptor 2 (beta) ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G F2 coagulation factor II ISO RGD PMID:21593018 RGD:5147754 NCBI chr 2:91,612,397...91,636,457
Ensembl chr 2:91,625,320...91,636,414
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Fasl Fas ligand (TNF superfamily, member 6) treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chr 1:161,780,691...161,788,495
Ensembl chr 1:161,780,689...161,788,495
JBrowse link
G Fcgr3 Fc receptor, IgG, low affinity III susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1801274 (human)
DNA:polymorphism: :p.A519G (human)
CTD PMID:19915573, PMID:20228799, PMID:19915573, PMID:20848524 RGD:5147922, RGD:5147918 NCBI chr 1:171,051,169...171,065,915
Ensembl chr 1:171,051,174...171,064,935
JBrowse link
G Gc vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chr 5:89,417,511...89,457,898
Ensembl chr 5:89,417,522...89,457,898
JBrowse link
G Ghrl ghrelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chr 6:113,716,119...113,719,911
Ensembl chr 6:113,716,119...113,719,880
JBrowse link
G Gna12 guanine nucleotide binding protein, alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 5:140,759,944...140,830,431
Ensembl chr 5:140,758,408...140,830,431
JBrowse link
G Gpr65 G-protein coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chr12:98,268,635...98,276,722
Ensembl chr12:98,268,635...98,276,644
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chr 9:108,339,080...108,340,342
Ensembl chr 9:108,338,903...108,340,343
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649, PMID:28626742, PMID:26604430 RGD:5490554, RGD:14700999, RGD:11538341 NCBI chr 3:108,012,250...108,017,973
Ensembl chr 3:108,012,255...108,017,973
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 susceptibility ISO DNA:deletion: : RGD PMID:17565649, PMID:26604430 RGD:5490554, RGD:11538341 NCBI chr10:75,783,813...75,798,584
Ensembl chr10:75,783,813...75,798,584
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 ISO RGD PMID:31038770 RGD:14865009 NCBI chr17:34,263,227...34,269,418
Ensembl chr17:34,257,689...34,269,419
JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:25559196 NCBI chr17:34,305,867...34,316,674
Ensembl chr17:34,305,867...34,316,674
JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr 7:56,050,124...56,231,800
Ensembl chr 7:56,050,196...56,231,800
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr 2:163,506,811...163,572,907
Ensembl chr 2:163,506,808...163,572,910
JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chr 2:24,002,911...24,049,758
Ensembl chr 2:24,002,910...24,049,394
JBrowse link
G Hspa4 heat shock protein 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chr11:53,259,814...53,300,479
Ensembl chr11:53,259,814...53,300,457
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO mRNA:increased expression:substantia nigra (rat)
CTD Direct Evidence: marker/mechanism
CTD PMID:15553846, PMID:20584104 RGD:4145388 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Icosl icos ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr10:78,069,368...78,079,525
Ensembl chr10:78,069,302...78,083,913
JBrowse link
G Igf1r insulin-like growth factor I receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chr 7:67,952,257...68,233,668
Ensembl chr 7:67,952,827...68,233,668
JBrowse link
G Igf2 insulin-like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chr 7:142,650,768...142,666,816
Ensembl chr 7:142,650,766...142,666,816
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr11:11,684,962...11,772,930
Ensembl chr11:11,685,003...11,772,926
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448, PMID:20228799, PMID:26660358, PMID:28120341 RGD:14975255, RGD:14975153 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il12b interleukin 12b ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799, PMID:21297633 NCBI chr11:44,400,063...44,414,677
Ensembl chr11:44,400,063...44,414,033
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 1:40,515,362...40,551,707
Ensembl chr 1:40,515,362...40,551,705
JBrowse link
G Il1b interleukin 1 beta ISO protein:increased expression:lung
CTD Direct Evidence: marker/mechanism
CTD PMID:12133438, PMID:15955209, PMID:20452301, PMID:22119283, PMID:24812904 RGD:10450593 NCBI chr 2:129,364,569...129,371,164
Ensembl chr 2:129,364,570...129,371,139
JBrowse link
G Il1r2 interleukin 1 receptor, type II ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 1:40,084,692...40,125,230
Ensembl chr 1:40,074,079...40,125,231
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136 NCBI chr 2:24,336,860...24,351,491
Ensembl chr 2:24,336,853...24,351,494
JBrowse link
G Il23r interleukin 23 receptor ISO DNA:SNP,Haplotype: :rs1884444(human)
CTD Direct Evidence: marker/mechanism
CTD PMID:18438406, PMID:19122664, PMID:20228799, PMID:23093364 RGD:8549574 NCBI chr 6:67,422,932...67,491,855
Ensembl chr 6:67,422,932...67,491,855
JBrowse link
G Il33 interleukin 33 severity
treatment
ISO
IEP
mRNA:increased expression:sigmoid colon RGD PMID:25112700, PMID:21037074, PMID:28802904 RGD:39938951, RGD:40813742, RGD:39938966 NCBI chr19:29,925,113...29,960,718
Ensembl chr19:29,925,114...29,960,718
JBrowse link
G Il7r interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr15:9,506,159...9,529,941
Ensembl chr15:9,505,788...9,530,176
JBrowse link
G Irf5 interferon regulatory factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 6:29,526,130...29,541,869
Ensembl chr 6:29,526,625...29,541,871
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr11:48,865,245...48,871,420
Ensembl chr11:48,861,968...48,871,683
JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:20228799, PMID:21297633, PMID:22269120 RGD:6483020 NCBI chr19:29,251,803...29,313,095
Ensembl chr19:29,251,828...29,313,080
JBrowse link
G Kdr kinase insert domain protein receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Kif21b kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 1:136,131,390...136,178,001
Ensembl chr 1:136,131,389...136,177,998
JBrowse link
G Lamb1 laminin B1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chr12:31,265,146...31,329,644
Ensembl chr12:31,265,234...31,329,644
JBrowse link
G Lsp1 lymphocyte specific 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr 7:142,458,223...142,494,868
Ensembl chr 7:142,460,809...142,494,867
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chr 9:111,019,292...111,042,766
Ensembl chr 9:111,019,271...111,042,767
JBrowse link
G Masp2 mannan-binding lectin serine peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chr 4:148,594,622...148,615,499
Ensembl chr 4:148,602,554...148,615,499
JBrowse link
G Mir155 microRNA 155 ISO miRNA:decreased expression:feces
miRNA:increased expression:colon
RGD PMID:30927737, PMID:29668922, PMID:29325325, PMID:29438285 RGD:21079443, RGD:24922213, RGD:24922207, RGD:21403682 NCBI chr16:84,714,140...84,714,204
Ensembl chr16:84,714,140...84,714,204
JBrowse link
G Mir31 microRNA 31 ISO miRNA:increased expression:colon RGD PMID:29438285 RGD:21403682 NCBI chr 4:88,910,557...88,910,662
Ensembl chr 4:88,910,557...88,910,662
JBrowse link
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) ISO RGD PMID:18837084 RGD:7207395 NCBI chr 9:7,464,141...7,476,869
Ensembl chr 9:7,464,141...7,476,869
JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826, PMID:22119283, PMID:24055189 NCBI chr11:87,793,784...87,804,412
Ensembl chr11:87,793,581...87,804,413
JBrowse link
G Mst1 macrophage stimulating 1 (hepatocyte growth factor-like) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799 NCBI chr 9:108,080,409...108,085,027
Ensembl chr 9:108,080,436...108,085,003
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chr13:68,560,780...68,582,169
Ensembl chr13:68,560,780...68,582,149
JBrowse link
G Muc2 mucin 2 ISO mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chr 7:141,690,340...141,754,691
Ensembl chr 7:141,690,340...141,754,693
JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405, PMID:18438406, PMID:20228799 NCBI chr19:43,612,325...43,615,892
Ensembl chr19:43,612,325...43,615,892
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 8:88,647,315...88,688,474
Ensembl chr 8:88,647,315...88,688,474
JBrowse link
G Ormdl3 ORM1-like 3 (S. cerevisiae) ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr11:98,581,294...98,587,245
Ensembl chr11:98,581,256...98,587,368
JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 6:5,168,090...5,193,987
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:colon (human) RGD PMID:17664137 RGD:5509924 NCBI chr 6:5,216,256...5,256,285
Ensembl chr 6:5,220,852...5,256,286
JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chr10:44,437,174...44,528,558
Ensembl chr10:44,437,177...44,528,501
JBrowse link
G Psmg1 proteasome (prosome, macropain) assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr16:95,979,933...95,990,960
Ensembl chr16:95,979,933...95,990,960
JBrowse link
G Ptger4 prostaglandin E receptor 4 (subtype EP4) ISO RGD PMID:21818367 RGD:6483532 NCBI chr15:5,233,399...5,244,187
Ensembl chr15:5,206,661...5,244,187
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 2:36,216,742...36,258,593
Ensembl chr 2:36,230,426...36,252,272
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17429720 RGD:2300267 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chr18:67,665,501...67,724,632
Ensembl chr18:67,665,511...67,724,595
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chr 4:16,122,732...16,163,678
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
G Rnf170 ring finger protein 170 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr 8:26,119,368...26,143,875
Ensembl chr 8:26,119,368...26,151,790
JBrowse link
G Sell selectin, lymphocyte ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chr 1:164,061,987...164,082,930
Ensembl chr 1:164,061,982...164,084,181
JBrowse link
G Selp selectin, platelet ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chr 1:164,115,264...164,150,026
Ensembl chr 1:164,115,264...164,150,026
JBrowse link
G Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 ISO DNA:transition, repeat:promoter:-237C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphism:promoter (human)
CTD PMID:16059695, PMID:18340647, PMID:11929588 RGD:5684939, RGD:5684968 NCBI chr 1:74,375,014...74,386,057
Ensembl chr 1:74,375,195...74,386,062
JBrowse link
G Slc26a3 solute carrier family 26, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chr12:31,433,142...31,473,922
Ensembl chr12:31,390,871...31,473,917
JBrowse link
G Sphk1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chr11:116,530,836...116,536,675
Ensembl chr11:116,530,925...116,536,674
Ensembl chr11:116,530,925...116,536,674
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism
CTD PMID:18438405, PMID:20228799, PMID:22269120 RGD:6483020 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Syne1 spectrin repeat containing, nuclear envelope 1 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chr10:5,020,192...5,550,692
Ensembl chr10:5,020,917...5,551,482
JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chr 2:148,404,471...148,408,188
Ensembl chr 2:148,404,466...148,408,188
JBrowse link
G Tnf tumor necrosis factor treatment IEP
ISO
CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD PMID:19617644, PMID:20452301, PMID:22119283, PMID:25204186, PMID:28120341, PMID:24812904 RGD:10450577, RGD:14975153, RGD:10450593 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chr 4:63,724,600...63,745,059
Ensembl chr 4:63,727,084...63,745,113
Ensembl chr 4:63,727,084...63,745,113
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chr 3:116,110,020...116,129,688
Ensembl chr 3:116,109,949...116,129,688
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma, large intestine mucosa RGD PMID:19013462 RGD:5684406 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vip vasoactive intestinal polypeptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chr10:5,639,193...5,647,617
Ensembl chr10:5,639,218...5,647,617
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chr 9:121,642,716...121,672,954
Ensembl chr 9:121,642,716...121,672,954
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 13427
    disease of anatomical entity 12903
      gastrointestinal system disease 4329
        intestinal disease 1461
          inflammatory bowel disease 319
            Crohn's disease + 105
            INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
            Inflammatory Bowel Disease 29 1
            Inflammatory Bowel Disease 30 0
            Neonatal Inflammatory Skin and Bowel Disease + 3
            colitis + 220
            inflammatory bowel disease 1 4
            inflammatory bowel disease 10 1
            inflammatory bowel disease 11 0
            inflammatory bowel disease 12 1
            inflammatory bowel disease 13 1
            inflammatory bowel disease 14 1
            inflammatory bowel disease 15 0
            inflammatory bowel disease 16 1
            inflammatory bowel disease 17 1
            inflammatory bowel disease 18 0
            inflammatory bowel disease 19 1
            inflammatory bowel disease 2 0
            inflammatory bowel disease 20 0
            inflammatory bowel disease 21 0
            inflammatory bowel disease 22 0
            inflammatory bowel disease 23 0
            inflammatory bowel disease 24 0
            inflammatory bowel disease 25 1
            inflammatory bowel disease 26 0
            inflammatory bowel disease 27 0
            inflammatory bowel disease 28 2
            inflammatory bowel disease 3 0
            inflammatory bowel disease 4 0
            inflammatory bowel disease 5 1
            inflammatory bowel disease 6 0
            inflammatory bowel disease 7 0
            inflammatory bowel disease 8 0
            inflammatory bowel disease 9 0
            ulcerative colitis + 111
Path 2
Term Annotations click to browse term
  disease 13427
    disease of anatomical entity 12903
      Immune & Inflammatory Diseases 3153
        Inflammation 1960
          gastroenteritis 394
            inflammatory bowel disease 319
              Crohn's disease + 105
              INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
              Inflammatory Bowel Disease 29 1
              Inflammatory Bowel Disease 30 0
              Neonatal Inflammatory Skin and Bowel Disease + 3
              colitis + 220
              inflammatory bowel disease 1 4
              inflammatory bowel disease 10 1
              inflammatory bowel disease 11 0
              inflammatory bowel disease 12 1
              inflammatory bowel disease 13 1
              inflammatory bowel disease 14 1
              inflammatory bowel disease 15 0
              inflammatory bowel disease 16 1
              inflammatory bowel disease 17 1
              inflammatory bowel disease 18 0
              inflammatory bowel disease 19 1
              inflammatory bowel disease 2 0
              inflammatory bowel disease 20 0
              inflammatory bowel disease 21 0
              inflammatory bowel disease 22 0
              inflammatory bowel disease 23 0
              inflammatory bowel disease 24 0
              inflammatory bowel disease 25 1
              inflammatory bowel disease 26 0
              inflammatory bowel disease 27 0
              inflammatory bowel disease 28 2
              inflammatory bowel disease 3 0
              inflammatory bowel disease 4 0
              inflammatory bowel disease 5 1
              inflammatory bowel disease 6 0
              inflammatory bowel disease 7 0
              inflammatory bowel disease 8 0
              inflammatory bowel disease 9 0
              ulcerative colitis + 111
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.