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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:inflammatory bowel disease
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Accession:DOID:0050589 term browser browse the term
Definition:An intestinal disease characterized by inflammation located in all parts of digestive tract. (DO)
Synonyms:exact_synonym: inflammatory bowel diseases
 narrow_synonym: CROHN DISEASE-ASSOCIATED GROWTH FAILURE, SUSCEPTIBILITY TO;   VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE;   regional enteritis;   ulcerative colitis
 related_synonym: Inflammatory bowel disease 1, susceptibility to
 primary_id: MESH:D015212
 xref: NCI:C3138;   OMIM:PS266600;   OMIM:PS614328
For additional species annotation, visit the Alliance of Genome Resources.


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inflammatory bowel disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:decreased expression:serum RGD PMID:18849144 RGD:5686819 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO RGD PMID:21939913 RGD:6767556 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479
JBrowse link
G Agt angiotensinogen ISO DNA:polymorphism: :p.M235T (human) RGD PMID:20717043 RGD:11039049 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Ano6 anoctamin 6 ISO associated with Spondylitis, Ankylosing;DNA:SNP: :rs17095830(human) RGD PMID:23308121 RGD:9684849 NCBI chrNW_004955500:4,462,314...4,652,634
Ensembl chrNW_004955500:4,462,524...4,652,782
JBrowse link
G Apc APC regulator of WNT signaling pathway ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004955495:6,466,434...6,489,612
Ensembl chrNW_004955495:6,467,357...6,489,633
JBrowse link
G Atg16l1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004955453:2,884,497...2,917,581
Ensembl chrNW_004955453:2,880,928...2,917,581
JBrowse link
G B2m beta-2-microglobulin ISO RGD PMID:20015205 RGD:6482693 NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568
JBrowse link
G Card9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345
JBrowse link
G Cdh2 cadherin 2 ISO RGD PMID:7502046 RGD:734737 NCBI chrNW_004955402:15,829,895...16,049,874
Ensembl chrNW_004955402:15,831,110...16,049,890
JBrowse link
G Cul2 cullin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955462:2,580,117...2,659,849
Ensembl chrNW_004955462:2,580,117...2,661,561
JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:14500559 RGD:5509042 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Fgf23 fibroblast growth factor 23 disease_progression ISO protein:increased expression:serum: RGD PMID:22551310 RGD:10044237 NCBI chrNW_004955413:2,182,459...2,192,279
Ensembl chrNW_004955413:2,182,459...2,192,279
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase ISO protein, mRNA:increased expression: colonic mucosa: inflamed tissue only RGD PMID:16195422 RGD:5688766 NCBI chrNW_004955403:32,569,841...32,614,860
Ensembl chrNW_004955403:32,569,841...32,613,763
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 ISO protein:increased expression RGD PMID:21864296 RGD:5685671 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:21135124 RGD:6218980 NCBI chrNW_004955412:23,863,513...23,867,984
Ensembl chrNW_004955412:23,862,590...23,867,984
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15638228, PMID:28067908 RGD:1625756 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:31062617 RGD:14975125 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf2 insulin like growth factor 2 disease_progression ISO protein:increased expression:serum RGD PMID:12548059, PMID:20683203 RGD:5509948, RGD:5509968 NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
JBrowse link
G Igfbp3 insulin like growth factor binding protein 3 ISO RGD PMID:15844718 RGD:1626117 NCBI chrNW_004955456:6,795,560...6,802,147
Ensembl chrNW_004955456:6,795,604...6,800,845
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:22018461 RGD:7495770 NCBI chrNW_004955536:611,965...658,647
Ensembl chrNW_004955536:612,774...658,647
JBrowse link
G Il10 interleukin 10 no_association
treatment
ISO DNA:SNP: :rs3024505 (human)
ClinVar Annotator: match by term: Inflammatory bowel disease
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs1800896 (human)
RGD
ClinVar
CTD
PMID:22511846, PMID:23291587, PMID:25741868, PMID:27468578, PMID:27783946, PMID:28411859, PMID:28492532, PMID:30290665, PMID:31062617 RGD:11534627, RGD:14975125, RGD:7364854 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chrNW_004955412:19,182,536...19,197,083
Ensembl chrNW_004955412:19,182,029...19,193,971
JBrowse link
G Il10rb interleukin 10 receptor subunit beta ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar NCBI chrNW_004955407:32,641,097...32,659,360
Ensembl chrNW_004955407:32,640,622...32,663,259
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955470:7,894,900...7,923,653
Ensembl chrNW_004955470:7,893,329...7,923,744
JBrowse link
G Il19 interleukin 19 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004955406:42,376,102...42,384,902
Ensembl chrNW_004955406:42,376,104...42,384,902
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO RGD PMID:12184521 RGD:10450573 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il21r interleukin 21 receptor ISO protein:increased expression:gut mucosa,leukocytes, mononuclear RGD PMID:19322899 RGD:6892935 NCBI chrNW_004955493:5,613,704...5,646,692
Ensembl chrNW_004955493:5,613,564...5,650,583
JBrowse link
G Il23r interleukin 23 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784, PMID:23291587, PMID:26192919 NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904
JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:24491821 RGD:39938952 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il5 interleukin 5 susceptibility ISO RGD PMID:22018693 RGD:5687148 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Crohn disease-associated growth failure, susceptibility to
CTD
ClinVar
PMID:9769329, PMID:10720087, PMID:11001912, PMID:11889177, PMID:12519862, PMID:12560873, PMID:12719374, PMID:15070960, PMID:15331795, PMID:15472205, PMID:16150725, PMID:16278864, PMID:17623760 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Inava innate immunity activator ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221
JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Itga4 integrin subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004955403:15,726,296...15,807,055
Ensembl chrNW_004955403:15,723,785...15,807,111
JBrowse link
G Itgal integrin subunit alpha L ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004955493:7,397,813...7,435,420
Ensembl chrNW_004955493:7,397,991...7,439,070
JBrowse link
G Itgb8 integrin subunit beta 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004955410:23,011,874...23,099,191
Ensembl chrNW_004955410:23,011,973...23,097,021
JBrowse link
G Klkb1 kallikrein B1 ISO RGD PMID:8625762 RGD:7327139 NCBI chrNW_004955403:22,835,544...22,856,355
Ensembl chrNW_004955403:22,833,982...22,856,389
JBrowse link
G Krt8 keratin 8 ISO ClinVar Annotator: match by term: Inflammatory bowel disease ClinVar PMID:15090596, PMID:25741868 NCBI chrNW_004955458:178,954...190,310 JBrowse link
G LOC102004641 cytochrome b-245 light chain ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:3368442, PMID:9445163, PMID:10440830, PMID:19388116, PMID:25741868, PMID:30709874 NCBI chrNW_004955541:2,570,843...2,573,822
Ensembl chrNW_004955541:2,569,727...2,574,118
JBrowse link
G Ltf lactotransferrin ISO RGD PMID:9791051 RGD:7243943 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO DNA:SNP: :1298A>C (human) RGD PMID:17111197 RGD:10449410 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Muc19 mucin 19, oligomeric ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955505:729...64,653 JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: REGIONAL ENTERITIS
ClinVar Annotator: match by term: Inflammatory bowel disease 1, susceptibility to
CTD
ClinVar
PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12512038, PMID:12557156, PMID:12577202, PMID:14765395, PMID:15024686, PMID:15190267, PMID:15198989, PMID:15571588, PMID:15770725, PMID:15967635, PMID:18240302, PMID:18489434, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22684479, PMID:23102769, PMID:24033266, PMID:25741868, PMID:26070941, PMID:26192919, PMID:26500656, PMID:28450277, PMID:28492532 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Nos2 nitric oxide synthase 2 ISO protein:increased expression:colon (rat) RGD PMID:21958875 RGD:5508753 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nox1 NADPH oxidase 1 ISO ClinVar Annotator: match by term: Very early onset inflammatory bowel disease ClinVar PMID:28492532, PMID:30709874 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618
JBrowse link
G Npsr1 neuropeptide S receptor 1 ISO RGD PMID:17854592 RGD:4891931 NCBI chrNW_004955560:1,069,651...1,243,111
Ensembl chrNW_004955560:1,069,651...1,243,111
JBrowse link
G Pdgfb platelet derived growth factor subunit B ISO RGD PMID:11780721 RGD:6482691 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987
JBrowse link
G Plcg2 phospholipase C gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004955522:4,352,890...4,480,735
Ensembl chrNW_004955522:4,358,233...4,468,986
JBrowse link
G Pomc proopiomelanocortin ISO protein:alternative form:large intestine epithelium: alphaMSH RGD PMID:9145424, PMID:21741932 RGD:5508804, RGD:5508805 NCBI chrNW_004955469:7,217,233...7,220,401
Ensembl chrNW_004955469:7,217,363...7,220,386
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11820457 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21983784 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Rassf1 Ras association domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24146755 NCBI chrNW_004955532:2,132,892...2,142,106
Ensembl chrNW_004955532:2,132,822...2,142,106
JBrowse link
G Sfrp1 secreted frizzled related protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004955536:1,663,721...1,702,678
Ensembl chrNW_004955536:1,663,344...1,703,514
JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18716850 NCBI chrNW_004955471:8,103,937...8,112,596
Ensembl chrNW_004955471:8,103,783...8,112,321
JBrowse link
G Slamf8 SLAM family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067908 NCBI chrNW_004955468:11,623,092...11,632,566
Ensembl chrNW_004955468:11,623,197...11,632,573
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphisms: :1730G>A (human)
DNA:point mutation:promoter:-237C>T (human)
CTD
RGD
PMID:16059695, PMID:16597321, PMID:21128323 RGD:5684929, RGD:5684952 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Slc6a14 solute carrier family 6 member 14 ISO protein:decreased expression:epithelial cell, colon RGD PMID:17065219 RGD:1625272 NCBI chrNW_004955534:3,463,057...3,488,577 JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:28891831, PMID:29483653 RGD:14995457 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
G Themis thymocyte selection associated ISO DNA:frameshift mutation: RGD PMID:22275874 RGD:38599149 NCBI chrNW_004955436:8,743,835...8,909,040 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12184521, PMID:15086448, PMID:27793764 RGD:10450573 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26192919 NCBI chrNW_004955419:12,863,617...12,884,498
Ensembl chrNW_004955419:12,863,615...12,879,517
JBrowse link
G Tpmt thiopurine S-methyltransferase treatment ISO RGD PMID:17026564 RGD:11038726 NCBI chrNW_004955483:8,052,867...8,072,235
Ensembl chrNW_004955483:8,052,849...8,072,764
JBrowse link
G Vegfa vascular endothelial growth factor A disease_progression ISO protein:increased expression:serum,colon: RGD PMID:23642997 RGD:11079180 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vnn1 vanin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:17145956 NCBI chrNW_004955436:13,238,307...13,266,800
Ensembl chrNW_004955436:13,238,603...13,259,577
JBrowse link
chemical colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin I converting enzyme 2 severity ISO Ace2 knockout RGD PMID:22837003 RGD:40818307 NCBI chrNW_004955519:2,591,229...2,643,705
Ensembl chrNW_004955519:2,591,248...2,633,495
JBrowse link
G Casp3 caspase 3 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp7 caspase 7 treatment ISO RGD PMID:28740344 RGD:13782278 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524
JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
Clostridium difficile colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23a interleukin 23 subunit alpha severity ISO RGD PMID:26455347 RGD:11097134 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Il33 interleukin 33 treatment
severity
ISO RGD PMID:32156806 RGD:40400894 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004955487:5,180,241...5,218,298
Ensembl chrNW_004955487:5,180,252...5,218,216
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO RGD PMID:17604368, PMID:21479819 RGD:5686754, RGD:5686898 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adk adenosine kinase ISO RGD PMID:11123368 RGD:6482664 NCBI chrNW_004955437:17,279,541...17,786,140
Ensembl chrNW_004955437:17,279,240...17,786,079
JBrowse link
G Adrb3 adrenoceptor beta 3 ISO mRNA:decreased expression:distal colon, mucosa (rat) RGD PMID:18492028 RGD:5684890 NCBI chrNW_004955463:13,663,064...13,665,553 JBrowse link
G Ahr aryl hydrocarbon receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27783946 NCBI chrNW_004955410:20,428,531...20,459,482 JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15821759 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909
JBrowse link
G Anxa1 annexin A1 ISO protein:increased expression:colon, neutrophil RGD PMID:10489933 RGD:2306920 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Apln apelin ISO RGD PMID:17391779 RGD:1626177 NCBI chrNW_004955473:5,346,822...5,356,359
Ensembl chrNW_004955473:5,346,747...5,356,359
JBrowse link
G Apoa4 apolipoprotein A4 ISO human protein in mouse model RGD PMID:15254593 RGD:5685667 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Aqp7 aquaporin 7 ISO associated with Infection;mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004955472:2,283,426...2,297,251 JBrowse link
G Arg1 arginase 1 severity ISO RGD PMID:28423665 RGD:39939041 NCBI chrNW_004955436:12,235,767...12,247,817
Ensembl chrNW_004955436:12,235,767...12,251,972
JBrowse link
G Arrb1 arrestin beta 1 ISO protein:increased expression:colon (rat) RGD PMID:21066892 RGD:5509893 NCBI chrNW_004955414:16,478,843...16,568,050
Ensembl chrNW_004955414:16,478,843...16,562,135
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment ISO RGD PMID:23840258 RGD:13792680 NCBI chrNW_004955495:6,664,394...6,666,693
Ensembl chrNW_004955495:6,664,394...6,666,693
JBrowse link
G Bdnf brain derived neurotrophic factor ISO protein:increased expression:dorsal root ganglion: RGD PMID:19932037 RGD:8657331 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588
JBrowse link
G Bmp6 bone morphogenetic protein 6 ISO RGD PMID:22361727 RGD:7242194 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Cat catalase ISO RGD PMID:21463646 RGD:5130869 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464
JBrowse link
G Cckbr cholecystokinin B receptor ISO RGD PMID:15102523 RGD:2311333 NCBI chrNW_004955414:22,001,351...22,011,275
Ensembl chrNW_004955414:22,000,436...22,011,433
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:19117124 RGD:6893503 NCBI chrNW_004955410:5,003,720...5,120,903
Ensembl chrNW_004955410:5,003,668...5,075,313
JBrowse link
G Cd40 CD40 molecule ISO RGD PMID:15591506 RGD:5508169 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Chek2 checkpoint kinase 2 ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:10617473, PMID:11053450, PMID:11479205, PMID:11719428, PMID:11967536, PMID:12094328, PMID:12533788, PMID:12690581, PMID:14648717, PMID:14648718, PMID:14648719, PMID:15122511, PMID:15488637, PMID:15492928, PMID:15520402, PMID:16257342, PMID:16492927, PMID:16880452, PMID:17085682, PMID:18172190, PMID:19338683, PMID:19805189, PMID:21807500, PMID:21956126, PMID:22006311, PMID:22058428, PMID:22419737, PMID:22811390, PMID:22994785, PMID:23469205, PMID:24033266, PMID:24884479, PMID:25431674, PMID:25741868, PMID:26084796, PMID:26467025, PMID:26641009, PMID:26681312, PMID:26822237, PMID:26845104, PMID:26884562, PMID:27083775, PMID:27153395, PMID:27269948, PMID:27433846, PMID:27751358, PMID:27798748, PMID:28125075, PMID:28135145, PMID:28195393, PMID:28492532, PMID:28503720, PMID:28514723, PMID:28727877, PMID:28734145, PMID:28779002, PMID:28802053, PMID:28874143, PMID:29351919, PMID:29489754, PMID:30311386 NCBI chrNW_004955455:2,969,113...3,008,004
Ensembl chrNW_004955455:2,969,270...3,003,173
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chrNW_004955507:6,066,026...6,102,066
Ensembl chrNW_004955507:6,067,203...6,102,001
JBrowse link
G Ciita class II major histocompatibility complex transactivator severity ISO protein:increased expression:T cells:constitutive expression of transgene increases severity
ClinVar Annotator: match by term: Colitis
RGD
ClinVar
PMID:17043423, PMID:25741868, PMID:28492532 RGD:5491188 NCBI chrNW_004955442:7,600,903...7,647,619
Ensembl chrNW_004955442:7,603,893...7,647,624
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO mRNA, protein:decreased expression:intestine, myenteric nerve plexus RGD PMID:17586086, PMID:21330446 RGD:5131259, RGD:5490987 NCBI chrNW_004955410:31,830,333...31,874,384
Ensembl chrNW_004955410:31,828,506...31,875,100
JBrowse link
G Ctsb cathepsin B ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chrNW_004955403:53,086,236...53,100,217
Ensembl chrNW_004955403:53,085,574...53,093,809
JBrowse link
G Ctss cathepsin S ISO protein:increased activity:cecum, colon, spinal cord RGD PMID:21802389 RGD:5686873 NCBI chrNW_004955413:99,279...124,793
Ensembl chrNW_004955413:99,159...124,042
JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO associated with Helicobacter Infections;mRNA:decreased expression:colon (mouse, Helicobacter hepaticus) RGD PMID:17242461 RGD:38549339 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
JBrowse link
G Dusp1 dual specificity phosphatase 1 severity ISO RGD PMID:22461024 RGD:7771532 NCBI chrNW_004955408:25,481,294...25,484,381
Ensembl chrNW_004955408:25,481,294...25,484,381
JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G Fgf19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chrNW_004955422:16,415,880...16,419,528
Ensembl chrNW_004955422:16,415,648...16,420,515
JBrowse link
G Flna filamin A ISO ClinVar Annotator: match by term: Colitis ClinVar PMID:25741868, PMID:28492532 NCBI chrNW_004955580:874,233...895,172
Ensembl chrNW_004955580:874,233...895,232
JBrowse link
G Gcg glucagon ISO CTD Direct Evidence: therapeutic CTD PMID:22323126 NCBI chrNW_004955449:11,708,152...11,716,429
Ensembl chrNW_004955449:11,708,152...11,716,429
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:19617644 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 ISO mRNA:increased expression:kidney: RGD PMID:23307618 RGD:7245473 NCBI chrNW_004955408:11,047,679...11,070,492 JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO protein:increased expression:colon:
CTD Direct Evidence: therapeutic
RGD
CTD
PMID:16365149, PMID:21444764, PMID:21853095, PMID:22261574 RGD:10766442, RGD:7207796 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Icos inducible T cell costimulator ISO protein:increased expression:T-cell RGD PMID:14731127 RGD:1624274 NCBI chrNW_004955457:10,934,390...10,952,318
Ensembl chrNW_004955457:10,934,341...10,952,404
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24782617 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO RGD PMID:17543437 RGD:2298659 NCBI chrNW_004955536:611,965...658,647
Ensembl chrNW_004955536:612,774...658,647
JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism|therapeutic RGD
CTD
PMID:19238344, PMID:21807089, PMID:21949848, PMID:22119709, PMID:22461024, PMID:23771723, PMID:24314293 RGD:7349385, RGD:7365024, RGD:7771532 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il17a interleukin 17A ISO mRNA:increased expression:colon
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:14962796, PMID:20881082, PMID:24548422 RGD:4781448, RGD:4888509 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:22969190, PMID:23810507, PMID:24548422 RGD:7204699 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1rl1 interleukin 1 receptor like 1 severity ISO RGD PMID:23172891 RGD:40400694 NCBI chrNW_004955470:7,779,828...7,849,157 JBrowse link
G Il33 interleukin 33 severity ISO RGD PMID:23172891, PMID:28423665 RGD:39939041, RGD:40400694 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il4 interleukin 4 treatment ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:9389741, PMID:24314293 RGD:8142400 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il5 interleukin 5 ISO protein: increased expression RGD PMID:22018693 RGD:5687148 NCBI chrNW_004955408:3,937,128...3,951,784
Ensembl chrNW_004955408:3,937,894...3,939,358
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22410118, PMID:24548422 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Itgb2 integrin subunit beta 2 ISO associated with Spirochaetales infections RGD PMID:11031123 RGD:6482227 NCBI chrNW_004955407:41,779,849...41,805,637
Ensembl chrNW_004955407:41,777,777...41,800,201
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Lct lactase ISO protein:decreased expression, increased expression:jejunum RGD PMID:17218984 RGD:1600240 NCBI chrNW_004955440:3,148,730...3,197,110
Ensembl chrNW_004955440:3,148,730...3,197,110
JBrowse link
G LOC102010850 cytochrome P450 1A1 ISO mRNA:increased expression:large intestine epithelium RGD PMID:21374063 RGD:5147670 NCBI chrNW_004955450:3,183,958...3,189,488
Ensembl chrNW_004955450:3,183,750...3,189,488
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO RGD PMID:21983832 RGD:5508401 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16917232 NCBI chrNW_004955495:7,190,009...7,194,966 JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: therapeutic RGD
CTD
PMID:12105854, PMID:17324399 RGD:1641979 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Msh2 mutS homolog 2 ISO RGD PMID:23883737 RGD:10412318 NCBI chrNW_004955441:14,188,315...14,247,608
Ensembl chrNW_004955441:14,187,805...14,247,698
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming treatment ISO mRNA:decreased expression:colon
protein:decreased sulfation:descending colon
RGD PMID:12395902, PMID:19220658, PMID:21949848, PMID:23395625 RGD:2324675, RGD:7349356, RGD:7349360, RGD:7349385 NCBI chrNW_004955476:11,108,826...11,135,697 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507 NCBI chrNW_004955410:10,717,664...10,742,109
Ensembl chrNW_004955410:10,717,664...10,751,177
JBrowse link
G Nod1 nucleotide binding oligomerization domain containing 1 ISO RGD PMID:20921147 RGD:5508755 NCBI chrNW_004955410:31,681,191...31,725,173
Ensembl chrNW_004955410:31,681,077...31,725,173
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO mRNA:increased expression:colon RGD PMID:16891783, PMID:20921147, PMID:21471573 RGD:1600781, RGD:5508727, RGD:5508755 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Nos2 nitric oxide synthase 2 ISO mRNA:increased expression:colon (mouse)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:8698225, PMID:16866779, PMID:17449036, PMID:21930116 RGD:4891411, RGD:5509045 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961
JBrowse link
G Nos3 nitric oxide synthase 3 ISO mRNA:increased expression:colon RGD PMID:17947450 RGD:2292124 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA, protein:increased expression:neuron RGD PMID:20638179 RGD:5684542 NCBI chrNW_004955545:2,929,704...2,947,579
Ensembl chrNW_004955545:2,929,704...2,947,579
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO mRNA, protein:increased expression:dorsal root ganglion RGD PMID:20638179 RGD:5684542 NCBI chrNW_004955432:2,284,283...2,629,631
Ensembl chrNW_004955432:2,288,898...2,630,878
JBrowse link
G Pgf placental growth factor ISO RGD PMID:20142801 RGD:6483587 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21244371 RGD:6482682 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha susceptibility ISO RGD PMID:20650341 RGD:5509936 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22126533 RGD:6484264 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:20833794 RGD:6483551 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:11820457, PMID:17543437 RGD:2298659 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18623154, PMID:23810507 RGD:2298776 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
JBrowse link
G Retn resistin treatment ISO RGD PMID:22630819 RGD:7207222 NCBI chrNW_004955563:1,607,814...1,609,273
Ensembl chrNW_004955563:1,607,814...1,609,273
JBrowse link
G Sell selectin L ISO RGD PMID:18054560 RGD:5685703 NCBI chrNW_004955462:7,591,997...7,611,408
Ensembl chrNW_004955462:7,591,366...7,612,846
JBrowse link
G Selp selectin P ISO protein:increased expression:colon RGD PMID:19147805 RGD:2312310 NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
JBrowse link
G Selplg selectin P ligand ISO RGD PMID:22009715 RGD:6218987 NCBI chrNW_004955455:9,883,271...9,892,572 JBrowse link
G Si sucrase-isomaltase ISO mRNA, protein:decreased expression:ileum RGD PMID:16964428 RGD:1625545 NCBI chrNW_004955448:14,686,315...14,777,298
Ensembl chrNW_004955448:14,685,963...14,777,338
JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940103, PMID:24548422, PMID:24782617 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19016783 RGD:5684975 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17551092 NCBI chrNW_004955445:19,213,210...19,227,670
Ensembl chrNW_004955445:19,215,161...19,228,695
JBrowse link
G Tac1 tachykinin precursor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chrNW_004955432:13,991,647...13,999,665
Ensembl chrNW_004955432:13,991,414...13,999,728
JBrowse link
G Tacr1 tachykinin receptor 1 ISO RGD PMID:18715640 RGD:2304260 NCBI chrNW_004955424:10,614,340...10,761,872
Ensembl chrNW_004955424:10,614,340...10,761,872
JBrowse link
G Tacr2 tachykinin receptor 2 ISO RGD PMID:12490601, PMID:18715640 RGD:2304260, RGD:5147478 NCBI chrNW_004955437:21,719,246...21,731,963
Ensembl chrNW_004955437:21,719,246...21,731,963
JBrowse link
G Tff1 trefoil factor 1 ISO RGD PMID:8836141 RGD:625375 NCBI chrNW_004955407:39,363,693...39,365,724 JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24548422 NCBI chrNW_004955405:41,613,976...41,655,813
Ensembl chrNW_004955405:41,613,966...41,655,813
JBrowse link
G Tlr3 toll like receptor 3 ISO mRNA:increased expression:large intestine mucosa (rat) RGD PMID:20011045 RGD:5128708 NCBI chrNW_004955403:22,977,882...23,001,392
Ensembl chrNW_004955403:22,979,120...23,001,467
JBrowse link
G Tlr4 toll like receptor 4 ISO protein:increased expression:colon RGD PMID:19002562, PMID:19924809 RGD:2312573, RGD:7794773 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23810507, PMID:24548422 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tst thiosulfate sulfurtransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19647029 NCBI chrNW_004955413:23,528,468...23,534,890
Ensembl chrNW_004955413:23,528,417...23,534,979
JBrowse link
G Ucn urocortin ISO mRNA:altered expression:distal colon (rat) RGD PMID:21330446 RGD:5490987 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641
JBrowse link
G Ucn2 urocortin 2 ISO mRNA:increased expression:colon (rat) RGD PMID:17586086 RGD:5131259 NCBI chrNW_004955532:648,845...650,020 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:colon: RGD PMID:22261574 RGD:7207796 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691
JBrowse link
G Vip vasoactive intestinal peptide ISO associated with Gram-Negative Bacterial Infections RGD PMID:19661153 RGD:5685605 NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792
JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 ISO RGD PMID:21295288 RGD:5685384 NCBI chrNW_004955579:1,160,620...1,212,711
Ensembl chrNW_004955579:1,160,620...1,209,848
JBrowse link
Crohn's disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:16432373, PMID:21829567 RGD:5686726 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Agt angiotensinogen ISO ClinVar Annotator: match by term: Crohn disease, association with ClinVar PMID:9120024, PMID:9894356, PMID:13937884, PMID:15077204, PMID:17047091, PMID:20978123 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357
JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chrNW_004955473:5,346,822...5,356,359
Ensembl chrNW_004955473:5,346,747...5,356,359
JBrowse link
G Apoa4 apolipoprotein A4 severity ISO protein:decreased expression:blood plasma (human) RGD PMID:17206692 RGD:5685660 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004955472:2,283,426...2,297,251 JBrowse link
G Atg16l1 autophagy related 16 like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756, PMID:18438406 NCBI chrNW_004955453:2,884,497...2,917,581
Ensembl chrNW_004955453:2,880,928...2,917,581
JBrowse link
G Bach2 BTB domain and CNC homolog 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955411:16,607,546...16,947,359
Ensembl chrNW_004955411:16,613,397...16,877,834
JBrowse link
G Bglap bone gamma-carboxyglutamate protein ISO protein:undercarboxylated:serum
mRNA:decreased expression:bone
RGD PMID:21482072, PMID:22535626 RGD:6483321, RGD:6483546 NCBI chrNW_004955545:2,381,091...2,382,114
Ensembl chrNW_004955545:2,381,156...2,381,978
JBrowse link
G Bpi bactericidal permeability increasing protein ISO RGD PMID:15758620 RGD:1580079 NCBI chrNW_004955445:18,393,854...18,433,948
Ensembl chrNW_004955445:18,391,215...18,427,980
JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004955462:5,937,292...6,088,310
Ensembl chrNW_004955462:5,937,292...6,088,310
JBrowse link
G Cd40 CD40 molecule susceptibility ISO DNA:SNP:5' utr:c.-1C>T (rs1883832) (human)
protein:increased expression:intestine, epithelial cell
RGD PMID:20133813, PMID:20634952 RGD:5490590, RGD:5490971 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Cibar2 CBY1 interacting BAR domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004955541:478,437...486,171
Ensembl chrNW_004955541:478,603...486,046
JBrowse link
G Cldn1 claudin 1 ISO RGD PMID:21748286 RGD:11341809 NCBI chrNW_004955420:17,798,974...17,815,049
Ensembl chrNW_004955420:17,798,974...17,815,205
JBrowse link
G Dennd1b DENN domain containing 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955406:34,021,508...34,241,735
Ensembl chrNW_004955406:34,027,046...34,241,737
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955469:7,264,431...7,367,059
Ensembl chrNW_004955469:7,269,952...7,367,059
JBrowse link
G Esr2 estrogen receptor 2 disease_progression ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G F13a1 coagulation factor XIII A chain ISO associated with Fistula;protein:decreased activity:plasma: RGD PMID:7611208 RGD:10450739 NCBI chrNW_004955465:7,444,118...7,617,366
Ensembl chrNW_004955465:7,443,166...7,617,436
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Fga fibrinogen alpha chain ISO RGD PMID:19683480 RGD:5688758 NCBI chrNW_004955471:8,806,964...8,814,671
Ensembl chrNW_004955471:8,806,650...8,816,791
JBrowse link
G Fn1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004955457:629,599...694,948
Ensembl chrNW_004955457:629,518...696,975
JBrowse link
G Fut2 fucosyltransferase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955559:1,857,138...1,868,315 JBrowse link
G Gc GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23566200 NCBI chrNW_004955453:15,109,711...15,112,438
Ensembl chrNW_004955453:15,109,711...15,112,438
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Hfe homeostatic iron regulator treatment ISO DNA:SNP: :rs2071303 (human) RGD PMID:27115882 RGD:14701051 NCBI chrNW_004955483:933,269...941,070
Ensembl chrNW_004955483:932,352...941,143
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO RGD PMID:15638228 RGD:1625756 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Ifng interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:21829567, PMID:28070144 RGD:14974261 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Igf1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004955405:37,505,830...37,582,152
Ensembl chrNW_004955405:37,512,201...37,582,152
JBrowse link
G Il10 interleukin 10 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:11113068, PMID:21102463, PMID:29899181 RGD:11049181, RGD:14975133 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Il21r interleukin 21 receptor ISO DNA:altered methylation: : RGD PMID:22021194 RGD:6482789 NCBI chrNW_004955493:5,613,704...5,646,692
Ensembl chrNW_004955493:5,613,564...5,650,583
JBrowse link
G Il23r interleukin 23 receptor susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNPs:multiple:
CTD
RGD
PMID:17068223, PMID:17435756, PMID:18438406 RGD:8549568 NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955421:22,642,004...22,694,729
Ensembl chrNW_004955421:22,641,511...22,694,913
JBrowse link
G Il6 interleukin 6 ISO OMIM NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438406, PMID:19165925, PMID:21278745 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human) RGD PMID:22269120 RGD:6483020 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Lep leptin ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472
JBrowse link
G LOC102025724 HLA class II histocompatibility antigen, DP alpha 1 chain ISO RGD PMID:12073072 RGD:6480648 NCBI chrNW_004955437:1,644,037...1,657,094
Ensembl chrNW_004955437:1,643,238...1,651,071
JBrowse link
G Lrrk2 leucine rich repeat kinase 2 ISO DNA:point mutation: :p.T2397M (rs3761863) (human) RGD PMID:21983832 RGD:5508401 NCBI chrNW_004955505:84,324...216,923
Ensembl chrNW_004955505:81,796...216,923
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 ISO RGD PMID:11703369 RGD:2311550 NCBI chrNW_004955495:7,190,009...7,194,966 JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:polymorphisms:cds: RGD PMID:21702710 RGD:12910842 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006
JBrowse link
G Mki67 marker of proliferation Ki-67 ISO RGD PMID:21364546 RGD:6483536 NCBI chrNW_004955477:5,847,288...5,875,970 JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004955532:1,590,685...1,595,655
Ensembl chrNW_004955532:1,590,755...1,595,148
JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:28002332 NCBI chrNW_004955486:2,096,379...2,112,240
Ensembl chrNW_004955486:2,096,379...2,112,240
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004955413:23,388,456...23,405,121
Ensembl chrNW_004955413:23,388,018...23,408,090
JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261, PMID:18438405, PMID:18438406 NCBI chrNW_004955507:5,454,871...5,457,247
Ensembl chrNW_004955507:5,455,087...5,457,660
JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19098911 NCBI chrNW_004955581:597,952...616,903
Ensembl chrNW_004955581:597,667...617,410
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 susceptibility
no_association
ISO DNA:frameshift mutation, missense mutations
DNA:missense mutations, frameshift mutation: :p.R702W, p.G908R, 3020_3021insC (human)
OMIM
RGD
PMID:11385576, PMID:21155887 RGD:1600778, RGD:5508730 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751
JBrowse link
G Ocln occludin ISO RGD PMID:21748286 RGD:11341809 NCBI chrNW_004955575:163,646...210,379 JBrowse link
G Pgf placental growth factor ISO protein:increased expression:serum RGD PMID:17980128 RGD:6483592 NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
JBrowse link
G Phox2b paired like homeobox 2B ISO CTD Direct Evidence: marker/mechanism CTD PMID:17435756 NCBI chrNW_004955443:5,935,975...5,938,747
Ensembl chrNW_004955443:5,935,975...5,938,747
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:21114432 RGD:6483800 NCBI chrNW_004955555:1,378,505...1,393,395
Ensembl chrNW_004955555:1,378,793...1,393,324
JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:terminal ileum RGD PMID:17664137 RGD:5509924 NCBI chrNW_004955432:11,945,383...11,983,417
Ensembl chrNW_004955432:11,942,922...11,983,504
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:21829567 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
G Prf1 perforin 1 ISO DNA:hypermethylation RGD PMID:22021194 RGD:6482789 NCBI chrNW_004955437:20,700,912...20,705,076
Ensembl chrNW_004955437:20,700,718...20,706,929
JBrowse link
G Prkcq protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO protein:increased expression:colon RGD PMID:21763290 RGD:5508200 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17554261 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Ptpn22 protein tyrosine phosphatase non-receptor type 22 ISO DNA:SNP:cds:rs2476601 (human) RGD PMID:18587394 RGD:6484668 NCBI chrNW_004955435:17,082,762...17,139,067 JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chrNW_004955462:7,591,997...7,611,408
Ensembl chrNW_004955462:7,591,366...7,612,846
JBrowse link
G Slc11a1 solute carrier family 11 member 1 no_association ISO DNA:polymorphism:promoter (human)
DNA:point mutation:promoter:-237C>T (human)
DNA:repeat, polymorphisms:promoter, intron:p.D543N (human)
DNA:polymorphism: :823C>T (human)
CTD Direct Evidence: marker/mechanism
DNA:polymorphisms:promoter (human)
DNA:insertion/deletion:3' utr (human)
RGD
CTD
PMID:11929588, PMID:15757519, PMID:16059695, PMID:17131479, PMID:17385031, PMID:18340647, PMID:18454481 RGD:5684938, RGD:5684939, RGD:5684941, RGD:5684942, RGD:5684952, RGD:5684956, RGD:5684968 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
DNA:SNPs: :rs744166, rs3816769 (human)
RGD PMID:20109474, PMID:22269120 RGD:6483020, RGD:6483027 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Tagap T cell activation RhoGTPase activating protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955439:3,479,041...3,488,403
Ensembl chrNW_004955439:3,478,708...3,488,777
JBrowse link
G Tcf7 transcription factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24994854 NCBI chrNW_004955408:5,362,423...5,388,684
Ensembl chrNW_004955408:5,362,084...5,388,527
JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Tlr4 toll like receptor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17914947 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
G Tlr9 toll like receptor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15236225, PMID:17914947 NCBI chrNW_004955532:3,828,645...3,832,699 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:intestine mucosa
CTD
RGD
PMID:10700533, PMID:21359923, PMID:21829567, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923, PMID:22531889 RGD:5130893, RGD:8661753 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:large intestine mucosa (rat) RGD PMID:21359923 RGD:5130893 NCBI chrNW_004955486:1,790,531...1,817,986
Ensembl chrNW_004955486:1,792,115...1,818,362
JBrowse link
G Tyk2 tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21102463 NCBI chrNW_004955495:1,618,099...1,637,996
Ensembl chrNW_004955495:1,617,999...1,636,068
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chrNW_004955420:28,234,590...28,253,146
Ensembl chrNW_004955420:28,234,153...28,253,168
JBrowse link
G Vtn vitronectin ISO CTD Direct Evidence: marker/mechanism CTD PMID:19751734 NCBI chrNW_004955481:4,765,078...4,768,027 JBrowse link
Experimental Colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 severity ISO mRNA,protein:decreased expression, decreased activity:colon: RGD PMID:26938296 RGD:35673322 NCBI chrNW_004955414:14,741,027...14,846,931
Ensembl chrNW_004955414:14,746,529...14,848,151
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment ISO RGD PMID:11884025 RGD:632022 NCBI chrNW_004955487:5,180,241...5,218,298
Ensembl chrNW_004955487:5,180,252...5,218,216
JBrowse link
G Adrb3 adrenoceptor beta 3 no_association ISO mRNA:unaltered expression:colon (rat) RGD PMID:11803250 RGD:5684894 NCBI chrNW_004955463:13,663,064...13,665,553 JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha treatment ISO RGD PMID:25689466 RGD:13703055 NCBI chrNW_004955402:31,652,226...31,662,114
Ensembl chrNW_004955402:31,651,960...31,662,762
JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:16689657 RGD:11039462 NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 treatment ISO RGD PMID:29655167 RGD:39939058 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
JBrowse link
G Ereg epiregulin ISO protein:increased expression:colonic mucosa (mouse) RGD PMID:20498653 RGD:39457688 NCBI chrNW_004955474:612,440...627,606
Ensembl chrNW_004955474:612,440...627,606
JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:22368862 RGD:10054108 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Foxp3 forkhead box P3 treatment ISO mRNA:increased expression:mucosa:
protein:increased expression:colon:
RGD PMID:17229795, PMID:26925602, PMID:27498708, PMID:28733028 RGD:14975101, RGD:38455994, RGD:38455995, RGD:38549362 NCBI chrNW_004955543:731,707...742,606
Ensembl chrNW_004955543:731,707...742,606
JBrowse link
G Hamp hepcidin antimicrobial peptide ISO protein:increased expression:colon RGD PMID:24764672 RGD:11041628 NCBI chrNW_004955468:4,576,080...4,577,591
Ensembl chrNW_004955468:4,575,510...4,577,649
JBrowse link
G Hsf1 heat shock transcription factor 1 ISO protein:increased acetylation:colon (rat) RGD PMID:25608526 RGD:10402402 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351
JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment ISO RGD PMID:10092309 RGD:11522714 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Ifng interferon gamma ISO protein:increased expression:plasma: RGD PMID:15030379, PMID:27498708 RGD:10755756, RGD:14975101 NCBI chrNW_004955458:14,643,333...14,648,020
Ensembl chrNW_004955458:14,643,313...14,648,045
JBrowse link
G Il10 interleukin 10 treatment ISO associated with Helicobacter Infections RGD PMID:16982822, PMID:25727887, PMID:27815529 RGD:11049170, RGD:11049485, RGD:14975260 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il1b interleukin 1 beta treatment ISO RGD PMID:31175857 RGD:14975282 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:8978354 RGD:8551835 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il2 interleukin 2 ISO RGD PMID:16630696 RGD:8662978 NCBI chrNW_004955428:18,163,010...18,168,157
Ensembl chrNW_004955428:18,162,467...18,168,265
JBrowse link
G Il23a interleukin 23 subunit alpha severity ISO mRNA:increased expression:colon (mouse) RGD PMID:24028683 RGD:39458035 NCBI chrNW_004955458:3,946,964...3,949,180
Ensembl chrNW_004955458:3,947,803...3,949,312
JBrowse link
G Il33 interleukin 33 severity
treatment
ISO RGD PMID:25112700, PMID:28423665 RGD:39938951, RGD:39939041 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:16133010, PMID:16630696, PMID:27096537 RGD:11062139, RGD:11062146, RGD:8662978 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Itga2 integrin subunit alpha 2 treatment ISO RGD PMID:16534417 RGD:11530069 NCBI chrNW_004955446:14,309,516...14,421,991
Ensembl chrNW_004955446:14,309,349...14,422,170
JBrowse link
G Itga4 integrin subunit alpha 4 ISO protein:increased expression:colon (rat) RGD PMID:12183646 RGD:729408 NCBI chrNW_004955403:15,726,296...15,807,055
Ensembl chrNW_004955403:15,723,785...15,807,111
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 ISO mRNA, protein:increased expression:colon RGD PMID:23986198 RGD:10412026 NCBI chrNW_004955437:14,749,808...15,457,274
Ensembl chrNW_004955437:14,749,914...15,454,028
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Kl klotho ISO mRNA:decreased expression:kidney: RGD PMID:20004202 RGD:10403055 NCBI chrNW_004955431:12,782,913...12,833,215
Ensembl chrNW_004955431:12,782,846...12,833,215
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:27028006 RGD:13800882 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29037916 RGD:13800567 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152
JBrowse link
G Mif macrophage migration inhibitory factor severity ISO RGD PMID:15807847 RGD:36947390 NCBI chrNW_004955455:8,367,566...8,368,460
Ensembl chrNW_004955455:8,367,566...8,368,460
JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775
JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO RGD PMID:23323009 RGD:13207328 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Mydgf myeloid derived growth factor severity
treatment
ISO associated with hymenolepiasis RGD PMID:19118508, PMID:20490892, PMID:27055194 RGD:11532263, RGD:39456118, RGD:39456129 NCBI chrNW_004955495:4,320,532...4,330,921
Ensembl chrNW_004955495:4,320,540...4,330,921
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 treatment ISO RGD PMID:22350949 RGD:10412739 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment ISO RGD PMID:21642017 RGD:10413866 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO protein:increased expression:colonic mucosa: RGD PMID:22997830 RGD:13204727 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Npy neuropeptide Y treatment ISO RGD PMID:20533056 RGD:10448943 NCBI chrNW_004955410:26,348,388...26,355,232
Ensembl chrNW_004955410:26,348,504...26,355,297
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chrNW_004955447:16,570,652...16,613,410
Ensembl chrNW_004955447:16,569,909...16,612,373
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta treatment ISO RGD PMID:24115822 RGD:11080973 NCBI chrNW_004955415:4,365,848...4,403,317
Ensembl chrNW_004955415:4,365,743...4,403,587
JBrowse link
G Phex phosphate regulating endopeptidase homolog X-linked ISO mRNA:decreased expression:bone: RGD PMID:16890604 RGD:11556253 NCBI chrNW_004955509:2,357,263...2,546,802
Ensembl chrNW_004955509:2,357,263...2,546,802
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma susceptibility ISO RGD PMID:20347874 RGD:38599183 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422
JBrowse link
G Ptger4 prostaglandin E receptor 4 treatment ISO RGD PMID:12100473 RGD:727388 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO RGD PMID:19116231 RGD:5684934 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Smad4 SMAD family member 4 susceptibility ISO RGD PMID:23090737 RGD:12880038 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538
JBrowse link
G Tnf tumor necrosis factor treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment ISO RGD PMID:21296062 RGD:8661763 NCBI chrNW_004955413:3,982,670...3,996,320
Ensembl chrNW_004955413:3,981,400...3,996,021
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
ileitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 ISO RGD PMID:22848538 RGD:8661712 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21945903 RGD:6892917 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353
JBrowse link
G Cd80 CD80 molecule ISO RGD PMID:22068168 RGD:6902902 NCBI chrNW_004955427:19,237,251...19,274,001
Ensembl chrNW_004955427:19,236,445...19,261,517
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27580383 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il17a interleukin 17A ISO mRNA:increased expression:ileum RGD PMID:18536735 RGD:4837793 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
JBrowse link
G Itgam integrin subunit alpha M ISO CTD Direct Evidence: marker/mechanism CTD PMID:10647630 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759
JBrowse link
G LOC102021597 alpha-1-antiproteinase S-like treatment ISO RGD PMID:23835442 RGD:14695050 NCBI chrNW_004955438:17,920,200...17,929,105 JBrowse link
G Tlr2 toll like receptor 2 ISO RGD PMID:18266231 RGD:2312714 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
JBrowse link
G Tlr4 toll like receptor 4 ISO RGD PMID:17255219, PMID:18266231 RGD:2312714, RGD:7241089 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135
JBrowse link
inflammatory bowel disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide binding oligomerization domain containing 2 ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar PMID:11385576, PMID:11385577, PMID:11425413, PMID:11875755, PMID:11910337, PMID:12019468, PMID:12115249, PMID:12512038, PMID:12557156, PMID:12577202, PMID:12626759, PMID:12630966, PMID:14508222, PMID:14765395, PMID:15024686, PMID:15044951, PMID:15190267, PMID:15198989, PMID:15320482, PMID:15459013, PMID:15571588, PMID:15712650, PMID:15770725, PMID:15967635, PMID:16278823, PMID:16485124, PMID:18056399, PMID:18240302, PMID:18419343, PMID:18489434, PMID:18507017, PMID:18541930, PMID:19467619, PMID:19713276, PMID:20032092, PMID:20230816, PMID:20959815, PMID:21274544, PMID:21335489, PMID:21548950, PMID:21830272, PMID:21914217, PMID:21983784, PMID:22319155, PMID:22684479, PMID:22926499, PMID:22942351, PMID:23102769, PMID:24033266, PMID:24391456, PMID:24583628, PMID:24803813, PMID:24960071, PMID:25741868, PMID:26070941, PMID:26164256, PMID:26316104, PMID:26500656, PMID:27306066, PMID:28492532, PMID:28814775 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Prkcq protein kinase C theta ISO ClinVar Annotator: match by term: Inflammatory bowel disease 1 ClinVar NCBI chrNW_004955421:23,072,607...23,151,591
Ensembl chrNW_004955421:23,070,955...23,175,699
JBrowse link
inflammatory bowel disease 10 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg16l1 autophagy related 16 like 1 ISO OMIM NCBI chrNW_004955453:2,884,497...2,917,581
Ensembl chrNW_004955453:2,880,928...2,917,581
JBrowse link
inflammatory bowel disease 13 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 ISO OMIM NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
inflammatory bowel disease 17 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il23r interleukin 23 receptor ISO OMIM NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904
JBrowse link
inflammatory bowel disease 19 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irgm immunity related GTPase M ISO OMIM NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
inflammatory bowel disease 25 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10rb interleukin 10 receptor subunit beta ISO OMIM NCBI chrNW_004955407:32,641,097...32,659,360
Ensembl chrNW_004955407:32,640,622...32,663,259
JBrowse link
inflammatory bowel disease 28 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10ra interleukin 10 receptor subunit alpha ISO OMIM NCBI chrNW_004955412:19,182,536...19,197,083
Ensembl chrNW_004955412:19,182,029...19,193,971
JBrowse link
Inflammatory Bowel Disease 29 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator ISO OMIM NCBI chrNW_004955406:37,086,302...37,107,221
Ensembl chrNW_004955406:37,086,302...37,107,221
JBrowse link
INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tgfb1 transforming growth factor beta 1 ISO OMIM NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441
JBrowse link
ischemic colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter:rs1799768 (human) RGD PMID:25656775 RGD:13208543 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142
JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:15770733 RGD:1580570 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 ISO OMIM NCBI chrNW_004955487:5,180,241...5,218,298
Ensembl chrNW_004955487:5,180,252...5,218,216
JBrowse link
G Iah1 isoamyl acetate hydrolyzing esterase 1 (putative) ISO ClinVar Annotator: match by term: Inflammatory skin and bowel disease, neonatal 1 ClinVar PMID:28492532 NCBI chrNW_004955487:5,172,505...5,180,132
Ensembl chrNW_004955487:5,172,505...5,180,132
JBrowse link
Neonatal Inflammatory Skin and Bowel Disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO OMIM NCBI chrNW_004955456:321,222...456,431 JBrowse link
Pediatric Crohn's Disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin ISO RGD PMID:21287673 RGD:5147769 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:11321389 RGD:7394742 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
Proctocolitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rn interleukin 1 receptor antagonist ISO protein:increased concentration:serum (human) RGD PMID:9802632 RGD:6909134 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
ulcerative colitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 susceptibility ISO RGD PMID:15505619 RGD:1598568 NCBI chrNW_004955432:4,911,774...5,085,349 JBrowse link
G Acsm3 acyl-CoA synthetase medium chain family member 3 ISO mRNA:decreased expression:colonic mucosa RGD PMID:21987487 RGD:7241281 NCBI chrNW_004955493:73,306...95,521
Ensembl chrNW_004955493:72,633...96,348
JBrowse link
G Adcy7 adenylate cyclase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28067910 NCBI chrNW_004955433:8,362,957...8,428,773
Ensembl chrNW_004955433:8,362,756...8,426,997
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:serum RGD PMID:16432373 RGD:5686726 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402
JBrowse link
G Adrb2 adrenoceptor beta 2 ISO protein:decreased expression:large intestine mucosa,spleen RGD PMID:22772914 RGD:7175063 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980
JBrowse link
G Apln apelin ISO protein:increased expression:intestine RGD PMID:17391779 RGD:1626177 NCBI chrNW_004955473:5,346,822...5,356,359
Ensembl chrNW_004955473:5,346,747...5,356,359
JBrowse link
G Apoa4 apolipoprotein A4 severity ISO DNA:missense mutation:cds:p.Q360H (human) RGD PMID:17206692 RGD:5685660 NCBI chrNW_004955412:18,158,095...18,160,636
Ensembl chrNW_004955412:18,155,801...18,160,701
JBrowse link
G Aqp7 aquaporin 7 severity ISO mRNA, protein:decreased expression:colon RGD PMID:15338270 RGD:1626292 NCBI chrNW_004955472:2,283,426...2,297,251 JBrowse link
G Arpc2 actin related protein 2/3 complex subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18836448 NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041
JBrowse link
G Brinp3 BMP/retinoic acid inducible neural specific 3 ISO mRNA,protein:decreased expression:intestine RGD PMID:25171508 RGD:14398484 NCBI chrNW_004955406:27,870,115...28,240,328
Ensembl chrNW_004955406:27,869,456...28,238,978
JBrowse link
G Btnl2 butyrophilin like 2 susceptibility ISO DNA:SNPs: : rs2294881,rs9268480,rs2076523(human) RGD PMID:19659809 RGD:9685032 NCBI chrNW_004955437:1,084,330...1,101,751
Ensembl chrNW_004955437:1,083,745...1,101,730
JBrowse link
G Card9 caspase recruitment domain family member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955513:4,350,873...4,359,345
Ensembl chrNW_004955513:4,350,147...4,359,345
JBrowse link
G Casp3 caspase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD
PMID:16306769, PMID:21887805 RGD:7488892 NCBI chrNW_004955453:6,846,625...6,850,007
Ensembl chrNW_004955453:6,846,549...6,850,031
JBrowse link
G Ccny cyclin Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004955462:5,937,292...6,088,310
Ensembl chrNW_004955462:5,937,292...6,088,310
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:21077277 RGD:6892920 NCBI chrNW_004955420:25,702,917...25,723,269
Ensembl chrNW_004955420:25,701,407...25,723,353
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16306769 NCBI chrNW_004955439:14,921,524...14,949,493
Ensembl chrNW_004955439:14,920,601...14,924,191
JBrowse link
G Cd40 CD40 molecule ISO protein:increased expression:intestine, epithelial cell RGD PMID:20133813 RGD:5490590 NCBI chrNW_004955445:11,191,817...11,202,156
Ensembl chrNW_004955445:11,190,603...11,202,093
JBrowse link
G Cdh1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004955484:7,782,409...7,861,082
Ensembl chrNW_004955484:7,782,772...7,860,967
JBrowse link
G Cdh3 cadherin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004955484:7,937,847...7,985,418
Ensembl chrNW_004955484:7,938,495...7,986,231
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A disease_progression ISO RGD PMID:15743319 RGD:8662406 NCBI chrNW_004955437:6,254,638...6,261,278
Ensembl chrNW_004955437:6,254,309...6,261,479
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO Protein:increased expression:large intestine mucosa RGD PMID:17011522 RGD:1600887 NCBI chrNW_004955407:42,091,211...42,131,343
Ensembl chrNW_004955407:42,091,211...42,131,343
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:17939044 RGD:5688304 NCBI chrNW_004955451:11,468,156...11,484,410
Ensembl chrNW_004955451:11,468,290...11,483,073
JBrowse link
G Cxcl8 C-X-C motif chemokine ligand 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12133438, PMID:15955209 NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955453:15,181,027...15,196,224
Ensembl chrNW_004955453:15,194,205...15,195,272
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chrNW_004955475:11,148,928...11,152,313
Ensembl chrNW_004955475:11,148,879...11,152,596
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 ISO mRNA:increased expression:peripheral blood immature plasma cells RGD PMID:21087446 RGD:6480657 NCBI chrNW_004955440:3,456,165...3,460,024
Ensembl chrNW_004955440:3,455,153...3,460,109
JBrowse link
G Dap death associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955426:398,593...452,004 JBrowse link
G Ecm1 extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406 NCBI chrNW_004955413:293,295...299,293
Ensembl chrNW_004955413:290,363...299,130
JBrowse link
G Esr2 estrogen receptor 2 ISO mRNA:decreased expression:colon RGD PMID:21252046 RGD:5508810 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946
JBrowse link
G F2 coagulation factor II, thrombin ISO RGD PMID:21593018 RGD:5147754 NCBI chrNW_004955422:1,356,675...1,367,788
Ensembl chrNW_004955422:1,356,769...1,367,517
JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455
JBrowse link
G Faslg Fas ligand treatment ISO RGD PMID:30122878 RGD:13792562 NCBI chrNW_004955406:13,098,479...13,107,045
Ensembl chrNW_004955406:13,098,662...13,107,389
JBrowse link
G Gc GC vitamin D binding protein susceptibility ISO DNA:polymorphism:cds:p.T420K(human) RGD PMID:21832969 RGD:5509866 NCBI chrNW_004955447:1,361,698...1,400,633
Ensembl chrNW_004955447:1,361,566...1,402,491
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19617644 NCBI chrNW_004955561:1,676,475...1,682,205
Ensembl chrNW_004955561:1,676,576...1,681,812
JBrowse link
G Gna12 G protein subunit alpha 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955460:12,534,210...12,628,090
Ensembl chrNW_004955460:12,534,168...12,622,537
JBrowse link
G Gpr65 G protein-coupled receptor 65 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30616622 NCBI chrNW_004955438:10,724,069...10,730,868
Ensembl chrNW_004955438:10,729,659...10,730,660
JBrowse link
G Gpx1 glutathione peroxidase 1 ISO protein:decreased expression:erythrocyte RGD PMID:20186929 RGD:11352754 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004955533:1,304,675...1,489,041
Ensembl chrNW_004955533:1,304,675...1,489,041
JBrowse link
G Hnf4a hepatocyte nuclear factor 4 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004955445:12,925,248...12,962,501
Ensembl chrNW_004955445:12,924,662...12,984,281
JBrowse link
G Hnmt histamine N-methyltransferase ISO RGD PMID:18340362 RGD:5509777 NCBI chrNW_004955440:5,084,198...5,137,577
Ensembl chrNW_004955440:5,084,081...5,139,348
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO protein:increased expression:colon mucosa, epithelium (human) RGD PMID:22297444 RGD:5688753 NCBI chrNW_004955408:4,379,825...4,422,710
Ensembl chrNW_004955408:4,379,825...4,423,381
JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:substantia nigra (rat)
CTD
RGD
PMID:15553846, PMID:20584104 RGD:4145388 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
JBrowse link
G Icoslg inducible T cell costimulator ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955407:41,190,875...41,197,521 JBrowse link
G Igf1r insulin like growth factor 1 receptor ISO protein:altered expression:colon RGD PMID:18938767 RGD:5686432 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Igf2 insulin like growth factor 2 disease_progression ISO RGD PMID:16088202 RGD:5509966 NCBI chrNW_004955422:13,880,525...13,907,963
Ensembl chrNW_004955422:13,880,471...13,888,566
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955456:3,617,988...3,721,791
Ensembl chrNW_004955456:3,635,380...3,721,791
JBrowse link
G Il10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:18836448, PMID:20228799, PMID:26660358, PMID:28120341 RGD:14975153, RGD:14975255 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779
JBrowse link
G Il12b interleukin 12B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799, PMID:21297633 NCBI chrNW_004955408:13,302,506...13,316,300
Ensembl chrNW_004955408:13,304,219...13,312,620
JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955470:7,894,900...7,923,653
Ensembl chrNW_004955470:7,893,329...7,923,744
JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD
RGD
PMID:12133438, PMID:15955209, PMID:20452301, PMID:22119283, PMID:24812904 RGD:10450593 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
JBrowse link
G Il1r2 interleukin 1 receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955470:7,518,565...7,562,219
Ensembl chrNW_004955470:7,518,663...7,559,470
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human) RGD PMID:8119534 RGD:6909136 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
JBrowse link
G Il23r interleukin 23 receptor ISO DNA:SNP,Haplotype: :rs1884444(human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18438406, PMID:19122664, PMID:20228799, PMID:23093364 RGD:8549574 NCBI chrNW_004955423:23,841,342...23,885,191
Ensembl chrNW_004955423:23,842,475...23,884,904
JBrowse link
G Il33 interleukin 33 severity
treatment
ISO mRNA:increased expression:sigmoid colon RGD PMID:21037074, PMID:25112700, PMID:28802904 RGD:39938951, RGD:39938966, RGD:40813742 NCBI chrNW_004955434:10,145,449...10,187,595
Ensembl chrNW_004955434:10,171,812...10,188,948
JBrowse link
G Il7r interleukin 7 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955426:20,785,896...20,818,512
Ensembl chrNW_004955426:20,787,471...20,818,577
JBrowse link
G Irgm immunity related GTPase M ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955408:2,338,510...2,344,566 JBrowse link
G Jak2 Janus kinase 2 ISO DNA:SNP: :rs10758669 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:20228799, PMID:21297633, PMID:22269120 RGD:6483020 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208
JBrowse link
G Kdr kinase insert domain receptor ISO protein:increased expression:colon RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955447:15,810,816...15,851,702
Ensembl chrNW_004955447:15,810,815...15,853,583
JBrowse link
G Kif21b kinesin family member 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955406:37,139,168...37,187,543
Ensembl chrNW_004955406:37,139,168...37,187,543
JBrowse link
G Lamb1 laminin subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915572 NCBI chrNW_004955410:12,241,235...12,305,433
Ensembl chrNW_004955410:12,241,235...12,305,433
JBrowse link
G Lsp1 lymphocyte specific protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955422:13,664,594...13,697,682
Ensembl chrNW_004955422:13,664,129...13,700,126
JBrowse link
G Ltf lactotransferrin ISO CTD Direct Evidence: therapeutic CTD PMID:16640825 NCBI chrNW_004955420:25,580,449...25,604,277
Ensembl chrNW_004955420:25,580,359...25,604,331
JBrowse link
G Masp2 mannan binding lectin serine peptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12904520 NCBI chrNW_004955486:2,641,730...2,655,125 JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22119283 NCBI chrNW_004955445:11,295,500...11,303,322
Ensembl chrNW_004955445:11,295,448...11,303,288
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20380826, PMID:22119283, PMID:24055189 NCBI chrNW_004955451:4,743,744...4,753,358
Ensembl chrNW_004955451:4,743,744...4,753,358
JBrowse link
G Mst1 macrophage stimulating 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438406, PMID:20228799 NCBI chrNW_004955532:1,590,685...1,595,655
Ensembl chrNW_004955532:1,590,755...1,595,148
JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase susceptibility ISO DNA:polymorphism: :66A>G (human) RGD PMID:21947961 RGD:5508217 NCBI chrNW_004955504:5,412,290...5,435,409
Ensembl chrNW_004955504:5,413,586...5,435,645
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming ISO mRNA:altered expression: : RGD PMID:12870797 RGD:2324685 NCBI chrNW_004955476:11,108,826...11,135,697 JBrowse link
G Nkx2-3 NK2 homeobox 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405, PMID:18438406, PMID:20228799 NCBI chrNW_004955507:5,454,871...5,457,247
Ensembl chrNW_004955507:5,455,087...5,457,660
JBrowse link
G Nod2 nucleotide binding oligomerization domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chrNW_004955433:8,746,213...8,780,119
Ensembl chrNW_004955433:8,746,004...8,782,710
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763
JBrowse link
G Pon1 paraoxonase 1 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chrNW_004955432:11,893,473...11,923,035
Ensembl chrNW_004955432:11,893,473...11,923,339
JBrowse link
G Pon3 paraoxonase 3 ISO mRNA:decreased expression:colon RGD PMID:17664137 RGD:5509924 NCBI chrNW_004955432:11,945,383...11,983,417
Ensembl chrNW_004955432:11,942,922...11,983,504
JBrowse link
G Prdm1 PR/SET domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21297633 NCBI chrNW_004955411:31,434,503...31,455,995
Ensembl chrNW_004955411:31,434,503...31,456,056
JBrowse link
G Psmg1 proteasome assembly chaperone 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955407:37,993,657...38,002,986
Ensembl chrNW_004955407:37,993,657...38,002,985
JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:21818367 RGD:6483532 NCBI chrNW_004955426:24,997,811...25,010,822
Ensembl chrNW_004955426:24,997,811...25,010,822
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17429720 RGD:2300267 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17429720 RGD:2300267 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171
JBrowse link
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438405 NCBI chrNW_004955402:771,410...846,671 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:15955209 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516
JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20452301 NCBI chrNW_004955417:6,669,675...6,698,142
Ensembl chrNW_004955417:6,669,675...6,702,228
JBrowse link
G Rnf170 ring finger protein 170 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chrNW_004955457:13,093,914...13,148,800
Ensembl chrNW_004955457:13,096,483...13,147,637
JBrowse link
G Sell selectin L ISO DNA:polymorphism: :p.F206L (human) RGD PMID:19212205 RGD:13464267 NCBI chrNW_004955462:7,591,997...7,611,408
Ensembl chrNW_004955462:7,591,366...7,612,846
JBrowse link
G Selp selectin P ISO protein:increased expression:serum RGD PMID:21526498 RGD:6218993 NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994
JBrowse link
G Slc11a1 solute carrier family 11 member 1 ISO DNA:transition, repeat:promoter:-237C>T (human)
DNA:polymorphism:promoter (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:11929588, PMID:16059695, PMID:18340647 RGD:5684939, RGD:5684968 NCBI chrNW_004955453:14,980,562...14,995,118
Ensembl chrNW_004955453:14,980,562...14,995,608
JBrowse link
G Slc26a3 solute carrier family 26 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19915573 NCBI chrNW_004955410:12,102,356...12,128,620
Ensembl chrNW_004955410:12,102,356...12,128,620
JBrowse link
G Sphk1 sphingosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24055189 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO DNA:SNP: :rs744166 (human)
CTD Direct Evidence: marker/mechanism
RGD
CTD
PMID:18438405, PMID:20228799, PMID:22269120 RGD:6483020 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO ClinVar Annotator: match by term: Ulcerative colitis ClinVar PMID:30311386 NCBI chrNW_004955439:9,131,227...9,574,112 JBrowse link
G Thbd thrombomodulin ISO protein:decreased expression:colon, blood vessel RGD PMID:17557119 RGD:5685011 NCBI chrNW_004955415:30,222,830...30,226,406 JBrowse link
G Tnf tumor necrosis factor treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:lung
CTD
RGD
PMID:19617644, PMID:20452301, PMID:22119283, PMID:24812904, PMID:25204186, PMID:28120341 RGD:10450577, RGD:10450593, RGD:14975153 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700
JBrowse link
G Tnfsf15 TNF superfamily member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20228799 NCBI chrNW_004955419:12,863,617...12,884,498
Ensembl chrNW_004955419:12,863,615...12,879,517
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15553846 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:colon, plasma RGD PMID:19013462 RGD:5684406 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Vip vasoactive intestinal peptide severity ISO mRNA:decreased expression:colon RGD PMID:22143367 RGD:5685619 NCBI chrNW_004955439:9,021,923...9,031,783
Ensembl chrNW_004955439:9,021,904...9,031,792
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 ISO RGD PMID:17611633 RGD:5685618 NCBI chrNW_004955420:28,234,590...28,253,146
Ensembl chrNW_004955420:28,234,153...28,253,168
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 11834
    disease of anatomical entity 11389
      gastrointestinal system disease 3761
        intestinal disease 1289
          inflammatory bowel disease 275
            Crohn's disease + 87
            INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
            Inflammatory Bowel Disease 29 1
            Inflammatory Bowel Disease 30 0
            Neonatal Inflammatory Skin and Bowel Disease + 3
            colitis + 194
            inflammatory bowel disease 1 2
            inflammatory bowel disease 10 1
            inflammatory bowel disease 11 0
            inflammatory bowel disease 12 0
            inflammatory bowel disease 13 1
            inflammatory bowel disease 14 0
            inflammatory bowel disease 15 0
            inflammatory bowel disease 16 0
            inflammatory bowel disease 17 1
            inflammatory bowel disease 18 0
            inflammatory bowel disease 19 1
            inflammatory bowel disease 2 0
            inflammatory bowel disease 20 0
            inflammatory bowel disease 21 0
            inflammatory bowel disease 22 0
            inflammatory bowel disease 23 0
            inflammatory bowel disease 24 0
            inflammatory bowel disease 25 1
            inflammatory bowel disease 26 0
            inflammatory bowel disease 27 0
            inflammatory bowel disease 28 1
            inflammatory bowel disease 3 0
            inflammatory bowel disease 4 0
            inflammatory bowel disease 5 0
            inflammatory bowel disease 6 0
            inflammatory bowel disease 7 0
            inflammatory bowel disease 8 0
            inflammatory bowel disease 9 0
            ulcerative colitis + 97
Path 2
Term Annotations click to browse term
  disease 11834
    disease of anatomical entity 11389
      Immune & Inflammatory Diseases 2724
        Inflammation 1651
          gastroenteritis 344
            inflammatory bowel disease 275
              Crohn's disease + 87
              INFLAMMATORY BOWEL DISEASE, IMMUNODEFICIENCY, AND ENCEPHALOPATHY 1
              Inflammatory Bowel Disease 29 1
              Inflammatory Bowel Disease 30 0
              Neonatal Inflammatory Skin and Bowel Disease + 3
              colitis + 194
              inflammatory bowel disease 1 2
              inflammatory bowel disease 10 1
              inflammatory bowel disease 11 0
              inflammatory bowel disease 12 0
              inflammatory bowel disease 13 1
              inflammatory bowel disease 14 0
              inflammatory bowel disease 15 0
              inflammatory bowel disease 16 0
              inflammatory bowel disease 17 1
              inflammatory bowel disease 18 0
              inflammatory bowel disease 19 1
              inflammatory bowel disease 2 0
              inflammatory bowel disease 20 0
              inflammatory bowel disease 21 0
              inflammatory bowel disease 22 0
              inflammatory bowel disease 23 0
              inflammatory bowel disease 24 0
              inflammatory bowel disease 25 1
              inflammatory bowel disease 26 0
              inflammatory bowel disease 27 0
              inflammatory bowel disease 28 1
              inflammatory bowel disease 3 0
              inflammatory bowel disease 4 0
              inflammatory bowel disease 5 0
              inflammatory bowel disease 6 0
              inflammatory bowel disease 7 0
              inflammatory bowel disease 8 0
              inflammatory bowel disease 9 0
              ulcerative colitis + 97
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.