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ONTOLOGY REPORT - ANNOTATIONS


Term:adult T-cell leukemia
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Accession:DOID:0050523 term browser browse the term
Definition:Aggressive T-Cell malignancy with adult onset, caused by HUMAN T-LYMPHOTROPIC VIRUS 1. It is endemic in Japan, the Caribbean basin, Southeastern United States, Hawaii, and parts of Central and South America and sub-Saharan Africa.
Synonyms:exact_synonym: ATLL;   Adult T-Cell Leukemia-Lymphomas;   Adult T-Cell Leukemias;   Adult T-cell leukemia/lymphoma;   HTLV Associated Leukemia Lymphoma;   HTLV I Associated T Cell Leukemia Lymphoma;   HTLV-Associated Leukemia-Lymphomas;   HTLV-I-Associated T-Cell Leukemia-Lymphomas;   Human T Cell Leukemia Lymphoma;   Human T Lymphotropic Virus Associated Leukemia Lymphoma;   Human T-Cell Leukemia-Lymphomas;   Leukemia Lymphoma, T Cell, Acute, HTLV I Associated
 primary_id: MESH:D015459;   RDO:0006879
 xref: GARD:13103
For additional species annotation, visit the Alliance of Genome Resources.


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adult T-cell leukemia term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:11554173
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:11554173
G Card11 caspase recruitment domain family, member 11 JBrowse link 12 15,700,600 15,844,512 RGD:11554173
G Ccr4 C-C motif chemokine receptor 4 JBrowse link 8 122,530,152 122,535,959 RGD:11554173
G Ccr7 C-C motif chemokine receptor 7 JBrowse link 10 87,057,335 87,067,444 RGD:11554173
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:11554173
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:6902938
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6902938
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:11554173
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:11554173
G Csnk2b casein kinase 2 beta JBrowse link 20 5,108,692 5,113,675 RGD:11554173
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:11554173
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:11049147
RGD:11049453
G Foxp3 forkhead box P3 JBrowse link X 15,753,175 15,768,648 RGD:11554173
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:11554173
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:11554173
G Gpr183 G protein-coupled receptor 183 JBrowse link 15 108,364,701 108,376,221 RGD:11554173
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 JBrowse link 4 81,237,496 81,241,281 RGD:11554173
G Icos inducible T-cell co-stimulator JBrowse link 9 67,748,157 67,786,808 RGD:11554173
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:10755707
RGD:11554173
G Ikzf2 IKAROS family zinc finger 2 JBrowse link 9 76,621,230 76,771,017 RGD:11554173
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:11049460
RGD:11554173
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:11554173
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:11554173
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:11354942
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:11060275
G Irf4 interferon regulatory factor 4 JBrowse link 17 34,886,746 34,905,191 RGD:11554173
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:11531131
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:11532670
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1580759
G Nras NRAS proto-oncogene, GTPase JBrowse link 2 205,553,119 205,563,716 RGD:11535055
G Plcg1 phospholipase C, gamma 1 JBrowse link 3 156,727,642 156,758,307 RGD:11554173
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:11554173
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:11554173
G Tal2 TAL bHLH transcription factor 2 JBrowse link 5 70,592,871 70,599,428 RGD:1599285
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:11554173
G Tlx1 T-cell leukemia, homeobox 1 JBrowse link 1 264,893,033 264,899,424 RGD:1599439
RGD:11554173
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1331525
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:11554173
G Vav1 vav guanine nucleotide exchange factor 1 JBrowse link 9 9,617,551 9,675,167 RGD:11554173

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15639
    disease of anatomical entity 14969
      hematopoietic system disease 1452
        leukocyte disease 443
          T-cell leukemia 58
            adult T-cell leukemia 40
Path 2
Term Annotations click to browse term
  disease 15639
    disease of anatomical entity 14969
      Hemic and Lymphatic Diseases 1724
        hematopoietic system disease 1452
          Hematologic Neoplasms 790
            hematologic cancer 789
              leukemia 573
                lymphocytic leukemia 277
                  T-cell leukemia 58
                    adult T-cell leukemia 40
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.