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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:cryptogenic organizing pneumonia
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Accession:DOID:0050157 term browser browse the term
Definition:An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a 'pneumonia-like' illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
Synonyms:exact_synonym: BOOP;   Bronchiolitis Obliterans Organizing Pneumonia;   Cryptogenic Organizing Pneumonias;   Cryptogenic organising pneumonitis;   Cryptogenic organizing pneumonitis;   bronchiolitis obliterans organising pneumonia;   cryptogenic organising pneumonia;   idiopathic bronchiolitis obliterans with organising pneumonia;   idiopathic bronchiolitis obliterans with organizing pneumonia
 primary_id: MESH:D018549
 alt_id: RDO:0007217
 xref: GARD:1620;   ICD10CM:J84.116;   ICD9CM:516.36;   NCI:C62586
For additional species annotation, visit the Alliance of Genome Resources.


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cryptogenic organizing pneumonia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf1a TNF receptor superfamily member 1A ISO protein:increased expression:lung, macrophage (human) RGD PMID:21144722 RGD:5131112 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO protein:increased expression:lung, lymphocyte (human) RGD PMID:21144722 RGD:5131112 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16091
    disease of anatomical entity 15341
      respiratory system disease 2711
        lung disease 1600
          pneumonia 261
            idiopathic interstitial pneumonia 71
              cryptogenic organizing pneumonia 2
Path 2
Term Annotations click to browse term
  disease 16091
    disease of anatomical entity 15341
      respiratory system disease 2711
        lower respiratory tract disease 1644
          lung disease 1600
            obstructive lung disease 436
              bronchitis 89
                bronchiolitis 76
                  bronchiolitis obliterans 37
                    cryptogenic organizing pneumonia 2
paths to the root