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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:angiosarcoma
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Accession:DOID:0001816 term browser browse the term
Definition:A rare malignant neoplasm characterized by rapidly proliferating, extensively infiltrating, anaplastic cells derived from blood vessels and lining irregular blood-filled or lumpy spaces. (Stedman, 25th ed)
Synonyms:exact_synonym: angiosarcomas;   hemangiosarcoma;   hemangiosarcomas
 primary_id: MESH:D006394
 alt_id: RDO:0001774
 xref: NCI:C122783;   NCI:C24016;   NCI:C3088;   NCI:C9275
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
 
angiosarcoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT2 angiopoietin 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
JBrowse link
G CCND1 cyclin D1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720
JBrowse link
G CSF3 colony stimulating factor 3 EXP CTD Direct Evidence: therapeutic CTD PMID:9774950 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813
JBrowse link
G CTNNB1 catenin beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:13678655 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
JBrowse link
G GJA4 gap junction protein alpha 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 1:34,792,958...34,795,747
Ensembl chr 1:34,792,999...34,795,747
JBrowse link
G HRAS HRas proto-oncogene, GTPase EXP CTD Direct Evidence: marker/mechanism CTD PMID:10930038 NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KDR kinase insert domain receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595
JBrowse link
G KRAS KRAS proto-oncogene, GTPase IAGP
EXP
ClinVar Annotator: match by term: Angiosarcoma
CTD Direct Evidence: marker/mechanism
ClinVar
CTD
PMID:8456858 PMID:10930038 PMID:12211074 PMID:13678655 PMID:20737008 PMID:24740626 PMID:25157968 PMID:25808193 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G MED12 mediator complex subunit 12 IAGP ClinVar Annotator: match by term: Angiosarcoma ClinVar PMID:26822237 NCBI chr  X:71,118,596...71,142,450
Ensembl chr  X:71,118,556...71,142,454
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G PLCG1 phospholipase C gamma 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24633157 NCBI chr20:41,137,519...41,177,626
Ensembl chr20:41,136,960...41,196,801
JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B EXP CTD Direct Evidence: marker/mechanism CTD PMID:24633157 NCBI chr12:70,515,870...70,637,440
Ensembl chr12:70,515,870...70,637,440
JBrowse link
G STAT3 signal transducer and activator of transcription 3 IDA protein:increased phosphorylation:blood vessel RGD PMID:18700251 RGD:8694308 NCBI chr17:42,313,324...42,388,502
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G TEK TEK receptor tyrosine kinase EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 9:27,109,141...27,230,178
Ensembl chr 9:27,109,141...27,230,174
JBrowse link
G TP53 tumor protein p53 ISO
EXP
CTD Direct Evidence: marker/mechanism CTD PMID:10626228 PMID:10930038 PMID:13678655 PMID:20737008 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G VEGFA vascular endothelial growth factor A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VEGFC vascular endothelial growth factor C EXP CTD Direct Evidence: marker/mechanism CTD PMID:17569031 NCBI chr 4:176,683,538...176,792,922
Ensembl chr 4:176,683,538...176,792,922
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 20158
    disease of cellular proliferation 7998
      Neoplasms by Histologic Type 5241
        cell type cancer 3769
          sarcoma 247
            angiosarcoma 20
              Postmastectomy Angiosarcoma 0
              Radiation Induced Angiosarcoma of the Breast 0
              Stewart Treves Syndrome 0
              aorta angiosarcoma 0
              breast angiosarcoma 0
              central nervous system angiosarcoma 0
              childhood angiosarcoma 0
              conventional angiosarcoma 0
              gallbladder angiosarcoma 0
              liver angiosarcoma + 0
              mediastinum angiosarcoma 0
              ovarian angiosarcoma 0
              prostate angiosarcoma 0
              skin angiosarcoma 0
              spleen angiosarcoma 0
              superior vena cava angiosarcoma 0
              thyroid angiosarcoma 0
Path 2
Term Annotations click to browse term
  disease 20158
    disease of cellular proliferation 7998
      cancer 5376
        organ system cancer 5214
          cardiovascular cancer 37
            vascular cancer 37
              angiosarcoma 20
                Postmastectomy Angiosarcoma 0
                Radiation Induced Angiosarcoma of the Breast 0
                Stewart Treves Syndrome 0
                aorta angiosarcoma 0
                breast angiosarcoma 0
                central nervous system angiosarcoma 0
                childhood angiosarcoma 0
                conventional angiosarcoma 0
                gallbladder angiosarcoma 0
                liver angiosarcoma + 0
                mediastinum angiosarcoma 0
                ovarian angiosarcoma 0
                prostate angiosarcoma 0
                skin angiosarcoma 0
                spleen angiosarcoma 0
                superior vena cava angiosarcoma 0
                thyroid angiosarcoma 0
paths to the root