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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Experimental Mammary Neoplasms
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Accession:DOID:9005233 term browser browse the term
Definition:Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
Synonyms:exact_synonym: Experimental Mammary Neoplasm
 primary_id: MESH:D008325


show annotations for term's descendants           Sort by:
Experimental Mammary Neoplasms term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 ISO RGD PMID:19654309 RGD:2315553 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G ABCG2A ATP binding cassette subfamily G member 2A ISO CTD Direct Evidence: therapeutic CTD PMID:22767648 NCBI chr 8:130,853,414...130,945,388
Ensembl chr 8:130,889,684...130,945,393 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr15:45,866,858...45,936,327
Ensembl chr15:45,866,857...45,963,729 		JBrowse link
G ACTB actin beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356 		JBrowse link
G ACTG1 actin gamma 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:1,320,355...1,323,219
Ensembl chr12:1,313,641...1,323,217 		JBrowse link
G ACTN4 actinin alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:47,493,834...47,565,999
Ensembl chr 6:47,493,919...47,565,998 		JBrowse link
G ADCY5 adenylate cyclase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr13:136,965,746...137,133,795
Ensembl chr13:136,972,801...137,135,347 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing disease_progression
treatment		 ISO RGD PMID:19447866 PMID:22246620 RGD:8694414 RGD:8694468 NCBI chr13:124,633,906...124,646,237
Ensembl chr13:124,633,685...124,646,646 		JBrowse link
G AFP alpha fetoprotein ISO CTD Direct Evidence: therapeutic CTD PMID:16322315 NCBI chr 8:69,677,690...69,698,864
Ensembl chr 8:69,677,690...69,698,864 		JBrowse link
G AGT angiotensinogen treatment ISO RGD PMID:20837666 RGD:5129167 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:8389152 PMID:18421211 RGD:2292665 NCBI chr13:88,934,873...88,980,317
Ensembl chr13:88,934,868...88,983,105 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8389152 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO RGD PMID:17210696 RGD:2315600
G AKT2 AKT serine/threonine kinase 2 ISO RGD PMID:17210696 RGD:2315600 NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,795...48,587,919 		JBrowse link
G ALCAM activated leukocyte cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:16316942 RGD:2306898 NCBI chr13:153,794,991...153,998,241
Ensembl chr13:153,794,993...153,998,208 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein ISO mRNA:increased expression:mammary gland tumor (rat) RGD PMID:18959458 RGD:2313895 NCBI chr11:7,371,328...7,438,111
Ensembl chr11:7,411,644...7,438,108 		JBrowse link
G ANTXR1 ANTXR cell adhesion molecule 1 disease_progression ISO RGD PMID:22085271 RGD:9684855 NCBI chr 3:73,157,744...73,398,379
Ensembl chr 3:73,157,747...73,398,379 		JBrowse link
G ANXA1 annexin A1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12376462 PMID:16316942 RGD:2306898 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279 		JBrowse link
G ANXA4 annexin A4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:72,623,311...72,654,591
Ensembl chr 3:72,622,358...72,694,212 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 ISO RGD PMID:14973070 RGD:2325748 NCBI chr 5:85,166,616...85,258,751
Ensembl chr 5:85,166,628...85,258,364 		JBrowse link
G APOE apolipoprotein E ISO RGD PMID:22469977 RGD:7771597 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G AR androgen receptor ISO RGD PMID:12150826 RGD:6482679 NCBI chr  X:53,609,113...53,806,778
Ensembl chr  X:53,609,176...53,800,677 		JBrowse link
G AREG amphiregulin ISO mRNA:increased expression:mammary gland
protein:increased expression:mammary gland		 RGD PMID:10225449 PMID:18421211 RGD:2292663 RGD:2292665 NCBI chr 8:70,417,935...70,428,106
Ensembl chr 8:70,417,923...70,428,102 		JBrowse link
G ARHGAP5 Rho GTPase activating protein 5 disease_progression ISO mRNA:increased expression:mammary gland RGD PMID:10939588 PMID:19703301 RGD:126848766 RGD:2316183 NCBI chr 7:67,494,237...67,631,461
Ensembl chr 7:67,494,941...67,594,197 		JBrowse link
G ATP5IF1 ATP synthase inhibitory factor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 6:85,307,242...85,309,211
Ensembl chr 6:85,307,189...85,309,215 		JBrowse link
G AURKA aurora kinase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:12124350 NCBI chr17:56,954,838...56,972,435 JBrowse link
G BAD BCL2 associated agonist of cell death severity
treatment		 ISO RGD PMID:20732338 PMID:23404339 RGD:10053670 RGD:10053708 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 ISO RGD PMID:19222350 RGD:2315700 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BARD1 BRCA1 associated RING domain 1 ISO RGD PMID:18443292 RGD:2293149 NCBI chr15:117,049,483...117,135,889
Ensembl chr15:117,047,845...117,175,851 		JBrowse link
G BASP1 brain abundant membrane attached signal protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr16:6,384,322...6,440,507 JBrowse link
G BAX BCL2 associated X, apoptosis regulator severity
treatment		 ISO RGD PMID:20732338 PMID:23404339 RGD:10053670 RGD:10053708 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:22668016 PMID:23404339 RGD:10053670 RGD:10054128 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO RGD PMID:23404339 RGD:10053670 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G BGN biglycan ISO CTD Direct Evidence: marker/mechanism CTD PMID:35234341 NCBI chr  X:124,282,048...124,295,450
Ensembl chr  X:124,275,305...124,295,445 		JBrowse link
G BRCA1 BRCA1 DNA repair associated susceptibility ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12203372 PMID:17505536 PMID:18443292 PMID:22767648 RGD:1599502 RGD:2293149 RGD:2293155 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668 		JBrowse link
G BST2 bone marrow stromal cell antigen 2 disease_progression ISO RGD PMID:23806386 RGD:14398495 NCBI chr 2:60,305,306...60,308,295
Ensembl chr 2:60,305,283...60,309,697 		JBrowse link
G CA9 carbonic anhydrase 9 ISO RGD PMID:17280655 RGD:2293194 NCBI chr 1:236,393,727...236,400,994
Ensembl chr 1:236,394,306...236,400,822 		JBrowse link
G CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase disease_progression ISO protein:increased expression:mammary gland RGD PMID:6030068 RGD:2303540 NCBI chr 3:111,887,017...111,914,511
Ensembl chr 3:111,887,020...111,914,492 		JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,682...77,912,617 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr  X:37,166,973...37,535,723
Ensembl chr  X:37,167,577...37,536,160 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase treatment ISO RGD PMID:10557324 RGD:2315886 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CASP3 caspase 3 treatment
severity		 ISO RGD PMID:20732338 PMID:23404339 PMID:26699876 RGD:10053670 RGD:10053708 RGD:13782283 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CASP7 caspase 7 treatment ISO RGD PMID:23404339 PMID:23979166 PMID:26699876 RGD:10053670 RGD:13209143 RGD:13782283 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,019,164...124,050,365 		JBrowse link
G CASP8 caspase 8 severity ISO RGD PMID:20732338 RGD:10053708 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468 		JBrowse link
G CASP9 caspase 9 severity
treatment		 ISO RGD PMID:17297389 PMID:20012353 PMID:20732338 PMID:26699876 RGD:10053708 RGD:13782283 RGD:2315928 RGD:2315933 NCBI chr 6:74,707,597...74,730,033
Ensembl chr 6:74,706,516...74,730,007 		JBrowse link
G CAV1 caveolin 1 treatment
onset		 ISO protein:decreased expression:mammary gland RGD PMID:9685399 PMID:15334058 PMID:15355971 RGD:2289100 RGD:2289106 RGD:8661780 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G CCNA2 cyclin A2 ISO protein:increased expression:mammary gland RGD PMID:10713672 RGD:2293347 NCBI chr 8:102,260,346...102,266,274
Ensembl chr 8:102,260,215...102,266,309 		JBrowse link
G CCNB1 cyclin B1 ISO RGD PMID:11146550 RGD:2315939 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377 		JBrowse link
G CCND1 cyclin D1 ISO protein:decreased expression:mammary gland
mRNA:increased expression:mammary gland (rat)
mRNA, protein:increased expression:mammary gland (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12376462 PMID:12602925 PMID:12649181 PMID:14522882 PMID:16316942 More... RGD:2289336 RGD:2289337 RGD:2292404 RGD:2296037 RGD:2306898 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CCND3 cyclin D3 ISO mRNA, protein:increased expression:mammary gland RGD PMID:12853979 PMID:16311245 RGD:2316015 RGD:2316020 NCBI chr 7:37,087,336...37,182,462
Ensembl chr 7:37,082,097...37,181,366 		JBrowse link
G CCNE1 cyclin E1 ISO protein:decreased expression:mammary gland RGD PMID:12602925 PMID:12649181 RGD:2289336 RGD:2289337 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363 		JBrowse link
G CCNH cyclin H ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland		 CTD
RGD		 PMID:12606953 RGD:9590264 NCBI chr 2:94,980,938...95,019,053
Ensembl chr 2:94,980,941...95,018,634 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 ISO RGD PMID:21621198 RGD:6893427 NCBI chr13:29,251,950...29,286,470
Ensembl chr13:29,285,012...29,376,343 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO RGD PMID:14597737 PMID:22637726 RGD:8551810 RGD:8551813 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CD274 CD274 molecule treatment ISO RGD PMID:29043842 RGD:40886270 NCBI chr 1:216,646,378...216,792,731
Ensembl chr 1:216,660,041...216,792,724 		JBrowse link
G CD40 CD40 molecule ISO RGD PMID:21137078 RGD:8547744 NCBI chr17:48,286,116...48,298,188
Ensembl chr17:48,286,029...48,298,528 		JBrowse link
G CD44 CD44 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153 		JBrowse link
G CDC25A cell division cycle 25A ISO RGD PMID:16951165 PMID:17283130 PMID:17638870 RGD:2754551 RGD:2764000 RGD:2771824
G CDC42 cell division cycle 42 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,123...80,089,233 		JBrowse link
G CDH1 cadherin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CDH13 cadherin 13 severity ISO RGD PMID:18316604 RGD:2293540 NCBI chr 6:4,809,752...5,832,188
Ensembl chr 6:4,808,255...5,832,415 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:16924466 RGD:2293558 NCBI chr 5:21,365,723...21,372,170
Ensembl chr 5:21,365,764...21,372,168 		JBrowse link
G CDK4 cyclin dependent kinase 4 susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:mammary gland		 CTD
RGD		 PMID:12376462 PMID:14522882 PMID:16413469 PMID:25221644 RGD:2293577 RGD:2293581 NCBI chr 5:23,039,206...23,041,959
Ensembl chr 5:23,038,891...23,042,061 		JBrowse link
G CDK6 cyclin dependent kinase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25221644 NCBI chr 9:72,510,858...72,765,631
Ensembl chr 9:72,518,101...72,764,129 		JBrowse link
G CDKL2 cyclin dependent kinase like 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25333262 NCBI chr 8:71,231,148...71,260,902
Ensembl chr 8:71,231,152...71,260,815 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B treatment ISO protein:increased expression:mammary gland RGD PMID:15844214 PMID:22651929 RGD:10045559 RGD:2293626 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A disease_progression ISO RGD PMID:18060046 PMID:20681787 RGD:2289674 RGD:8552689 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G CDS1 CDP-diacylglycerol synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 8:133,959,250...134,041,258
Ensembl chr 8:133,959,247...134,041,258 		JBrowse link
G CLU clusterin disease_progression ISO RGD PMID:23099883 RGD:8699504 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G CNN3 calponin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 4:122,504,450...122,528,351
Ensembl chr 4:122,504,433...122,528,348 		JBrowse link
G COL18A1 collagen type XVIII alpha 1 chain severity ISO RGD PMID:10766159 RGD:70690 NCBI chr13:207,907,835...207,984,082
Ensembl chr13:207,940,948...207,982,938 		JBrowse link
G COL5A1 collagen type V alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:273,934,219...274,083,264
Ensembl chr 1:273,971,971...274,085,111 		JBrowse link
G CSF1 colony stimulating factor 1 ISO RGD PMID:15205327 RGD:2293710 NCBI chr 4:110,178,466...110,198,232
Ensembl chr 4:110,178,475...110,197,900 		JBrowse link
G CSN2 casein beta ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:9879772 PMID:16316942 RGD:2306898 NCBI chr 8:66,914,231...66,922,636
Ensembl chr 8:66,915,923...66,922,636 		JBrowse link
G CSN3 casein kappa ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:16316942 RGD:2306898 NCBI chr 8:67,099,131...67,109,112
Ensembl chr 8:67,099,131...67,106,987 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 ISO RGD PMID:11827167 RGD:727632 NCBI chr17:34,692,960...34,748,067 JBrowse link
G CTNNB1 catenin beta 1 ISO protein:increased expression:mammary gland
DNA:missense mutations: :p.S33Y, p.S45F		 RGD PMID:17510243 PMID:18060046 RGD:2289674 RGD:2289816 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr15:24,895,575...24,900,710
Ensembl chr15:24,895,522...24,906,372 		JBrowse link
G DDR1 discoidin domain receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21283680 PMID:29298894 RGD:151347446 NCBI chr 7:23,371,358...23,391,585
Ensembl chr 7:23,373,845...23,391,584 		JBrowse link
G DES desmin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr15:121,428,539...121,435,426
Ensembl chr15:121,427,642...121,435,423 		JBrowse link
G DIO1 iodothyronine deiodinase 1 ISO RGD PMID:11765219 RGD:727335 NCBI chr 6:158,376,744...158,392,745
Ensembl chr 6:158,375,602...158,392,754 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta treatment ISO RGD PMID:24447120 RGD:9588304 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072 		JBrowse link
G DUSP1 dual specificity phosphatase 1 treatment ISO RGD PMID:20837666 RGD:5129167 NCBI chr16:51,457,924...51,461,095
Ensembl chr16:51,458,020...51,461,086 		JBrowse link
G DUSP6 dual specificity phosphatase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:93,303,058...93,307,510
Ensembl chr 5:93,302,975...93,307,504 		JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:92,421,235...92,425,053
Ensembl chr 1:92,421,230...92,425,044 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:85,407,677...85,473,251
Ensembl chr 3:85,407,677...85,473,252 		JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:2523869 PMID:8603490 PMID:17203220 RGD:2289979 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:52,659,040...52,664,686 JBrowse link
G ENO1 enolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G EPCAM epithelial cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:93,169,800...93,185,221
Ensembl chr 3:93,168,852...93,185,653 		JBrowse link
G EPHX1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr10:13,757,489...13,773,071
Ensembl chr10:13,751,881...13,773,072 		JBrowse link
G EPO erythropoietin treatment ISO RGD PMID:12118093 RGD:11041669 NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936 		JBrowse link
G EPOR erythropoietin receptor treatment ISO RGD PMID:12118093 RGD:11041669 NCBI chr 2:70,063,601...70,068,821
Ensembl chr 2:70,063,519...70,068,821 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 ISO CTD Direct Evidence: marker/mechanism
Androgen-dependent		 CTD
RGD		 PMID:1913683 PMID:8603490 PMID:12150826 PMID:17203220 PMID:25221644 RGD:2289920 RGD:2289979 RGD:6482679 NCBI chr12:22,591,621...22,621,384
Ensembl chr12:22,590,725...22,621,351 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:17203220 RGD:2289979 NCBI chr 5:21,474,218...21,495,040
Ensembl chr 5:21,474,475...21,495,038 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:17203220 RGD:2289979 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565 		JBrowse link
G ESR1 estrogen receptor 1 susceptibility ISO protein:increased expression:epithelial cell, nucleus
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:11759285 PMID:15637090 PMID:18055862 RGD:2290019 RGD:8552983 RGD:8553057 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G ESR2 estrogen receptor 2 treatment ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:epithelial cell, nucleus		 RGD
CTD		 PMID:15637090 PMID:24078029 RGD:7364911 RGD:8552983 NCBI chr 1:193,823,666...193,907,330
Ensembl chr 1:193,829,560...193,906,565 		JBrowse link
G EZR ezrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:8,403,362...8,452,750
Ensembl chr 1:8,403,453...8,452,742 		JBrowse link
G F11R F11 receptor ISO RGD PMID:22120722 RGD:7488922 NCBI chr 4:89,425,101...89,447,889
Ensembl chr 4:89,425,018...89,449,599 		JBrowse link
G FABP4 fatty acid binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:18094967 RGD:2290047 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FBXO10 F-box protein 10 ISO RGD PMID:17404222 RGD:1601189 NCBI chr 1:238,232,855...238,308,661
Ensembl chr 1:238,232,867...238,308,625 		JBrowse link
G FGF10 fibroblast growth factor 10 ISO mRNA:increased expression:mammary gland RGD PMID:18421211 RGD:2292665 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509 		JBrowse link
G FGF7 fibroblast growth factor 7 ISO RGD PMID:9000125 RGD:2301094 NCBI chr 1:122,215,878...122,278,705
Ensembl chr 1:122,215,882...122,277,750 		JBrowse link
G FGF8 fibroblast growth factor 8 ISO RGD PMID:9840935 RGD:2301098 NCBI chr14:112,808,215...112,814,225
Ensembl chr14:112,808,162...112,814,248 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 ISO RGD PMID:10498246 RGD:2302211 NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,370,496...5,455,358 		JBrowse link
G FN1 fibronectin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014 		JBrowse link
G FRMPD1 FERM and PDZ domain containing 1 ISO RGD PMID:17404222 RGD:1601189 NCBI chr 1:238,371,311...238,511,714
Ensembl chr 1:238,371,336...238,511,715 		JBrowse link
G FURIN furin, paired basic amino acid cleaving enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 7:53,455,634...53,472,791
Ensembl chr 7:53,460,017...53,472,787 		JBrowse link
G G0S2 G0/G1 switch 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 9:133,287,065...133,288,066
Ensembl chr 9:133,287,325...133,287,742 		JBrowse link
G GATA3 GATA binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G GATM glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:126,361,968...126,378,705
Ensembl chr 1:126,361,945...126,380,871 		JBrowse link
G GDA guanine deaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:225,425,389...225,589,835
Ensembl chr 1:225,403,138...225,589,827 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr13:32,705,326...32,733,804
Ensembl chr13:32,705,321...32,733,794 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO RGD PMID:28810530 RGD:13792729 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
G GSN gelsolin ISO mRNA:decreased expression RGD PMID:8895730 RGD:1599869 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848 		JBrowse link
G GSS glutathione synthetase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr17:38,316,199...38,342,253
Ensembl chr17:38,312,720...38,342,298 		JBrowse link
G H2AX H2A.X variant histone treatment ISO RGD PMID:22384017 RGD:7240549 NCBI chr 9:46,308,824...46,310,494
Ensembl chr 9:46,309,653...46,310,084 		JBrowse link
G H3-3B H3.3 histone B ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:5,632,326...5,634,977
Ensembl chr12:5,632,365...5,634,726 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha treatment ISO RGD PMID:17280655 RGD:2293194 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:16319139 PMID:23215791 RGD:10755708
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,417 		JBrowse link
G HNRNPAB heterogeneous nuclear ribonucleoprotein A/B ISO CTD Direct Evidence: marker/mechanism CTD PMID:15538050 NCBI chr 2:80,186,998...80,194,155 JBrowse link
G HP haptoglobin treatment ISO RGD PMID:23880232 RGD:11041861 NCBI chr 6:14,980,382...14,985,245 JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO CTD Direct Evidence: marker/mechanism
DNA:mutation: :p.G12E (rat)		 CTD
RGD		 PMID:8185828 PMID:11376698 PMID:19652463 RGD:2314834 NCBI chr 2:299,662...302,539
Ensembl chr 2:299,660...302,501 		JBrowse link
G ID1 inhibitor of DNA binding 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,316,514...35,317,736 		JBrowse link
G ID3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:81,422,541...81,424,169
Ensembl chr 6:81,422,546...81,424,075 		JBrowse link
G ID4 inhibitor of DNA binding 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14633621 NCBI chr 7:15,281,535...15,284,895
Ensembl chr 7:15,281,757...15,282,839 		JBrowse link
G IGF1 insulin like growth factor 1 ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:15217511 PMID:15528971 PMID:17584969 PMID:23342276 RGD:8549490 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033 		JBrowse link
G IL10 interleukin 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14999141 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL18BP interleukin 18 binding protein ISO mRNA:increased expression:mammary gland RGD PMID:18959458 RGD:2313895 NCBI chr 9:6,586,602...6,596,423
Ensembl chr 9:6,488,808...6,591,333 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a mouse model RGD PMID:21890879 RGD:6771361
G IL6ST interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr16:35,101,304...35,151,832
Ensembl chr16:35,101,306...35,192,220 		JBrowse link
G ILK integrin linked kinase ISO late onset development of tumors in transgenic mice overexpressing human ILK in mammary glands RGD PMID:11704830 RGD:2301733 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858 		JBrowse link
G INSIG1 insulin induced gene 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G ITGB3 integrin subunit beta 3 ISO protein:increased expression:mammary gland: RGD PMID:22022542 RGD:8693386 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292 		JBrowse link
G KDR kinase insert domain receptor ISO inhibition prevents DMBA-induced atypical ductal hyperplasia and carcinoma in situ RGD PMID:15170218 PMID:19888452 RGD:2291936 RGD:5684399 NCBI chr 8:41,809,116...41,856,379
Ensembl chr 8:41,809,122...41,856,336 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO DNA:mutation (rat) RGD PMID:18445266 RGD:2302172 NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,734 		JBrowse link
G KITLG KIT ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:94,016,992...94,110,219
Ensembl chr 5:94,017,387...94,110,214 		JBrowse link
G KRT5 keratin 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:17,862,047...17,868,397
Ensembl chr 5:17,862,051...17,868,402 		JBrowse link
G KRT7 keratin 7 ISO RGD PMID:8570173 RGD:2317439 NCBI chr 5:17,553,192...17,570,582
Ensembl chr 5:17,555,728...17,570,581 		JBrowse link
G KRT71 keratin 71 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:17,895,714...17,905,194
Ensembl chr 5:17,895,718...17,905,181 		JBrowse link
G LEP leptin treatment ISO RGD PMID:22246620 RGD:8694468 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LGALS7 galectin 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:47,588,983...47,604,520 JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO mRNA:splice variant (rat) RGD PMID:15044717 RGD:2302177 NCBI chr 3:91,964,415...92,023,821
Ensembl chr 3:91,964,415...92,021,398 		JBrowse link
G LIN7A lin-7 homolog A, crumbs cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 5:100,533,630...100,686,709
Ensembl chr 5:100,538,065...100,674,551 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO CTD Direct Evidence: marker/mechanism
protein:increased expression:serum		 CTD
RGD		 PMID:16619500 RGD:1582109 NCBI chr 2:103,568,366...103,659,589
Ensembl chr 2:103,567,602...103,661,070 		JBrowse link
G LOC100624785 tubulin beta-2A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 7:1,910,585...1,914,668
Ensembl chr 7:1,910,269...1,914,761 		JBrowse link
G LOC100737977 tumor necrosis factor receptor superfamily member 10B-like ISO RGD PMID:17671220 RGD:2290495 NCBI chr14:7,344,788...7,371,086 JBrowse link
G LOC110259958 hemoglobin subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:41,482,353...41,483,564 JBrowse link
G LPL lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
G LSR lipolysis stimulated lipoprotein receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 6:44,759,091...44,773,378
Ensembl chr 6:44,759,073...44,773,379 		JBrowse link
G MAP2K3 mitogen-activated protein kinase kinase 3 ISO RGD PMID:24233520 RGD:7495808 NCBI chr12:61,396,337...61,417,333
Ensembl chr12:61,396,369...61,417,321 		JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21317887 NCBI chr 2:71,299,010...71,308,432
Ensembl chr 2:71,298,325...71,308,124 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:29435821 RGD:13800872 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:29435821 RGD:13800872 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MDH2 malate dehydrogenase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:10,120,121...10,132,705
Ensembl chr 3:10,120,083...10,132,752 		JBrowse link
G MGP matrix Gla protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 5:57,665,272...57,669,360
Ensembl chr 5:57,665,248...57,669,764 		JBrowse link
G MIF macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:49,840,303...49,841,063
Ensembl chr14:49,840,305...49,841,068 		JBrowse link
G MIR155 microRNA mir-155 ISO RGD PMID:20354188 PMID:29643534 RGD:21079418 RGD:21403681 NCBI chr13:189,138,822...189,138,902
Ensembl chr13:189,138,822...189,138,902 		JBrowse link
G MMP1 matrix metallopeptidase 1 treatment ISO RGD PMID:19622769 RGD:8549722 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP13 matrix metallopeptidase 13 severity ISO RGD PMID:18698413 RGD:2306081 NCBI chr 9:33,549,003...33,616,700
Ensembl chr 9:33,549,008...33,561,162 		JBrowse link
G MMP15 matrix metallopeptidase 15 ISO mRNA:increased expression:mammary gland RGD PMID:15895410 RGD:2314949 NCBI chr 6:19,890,867...19,912,941
Ensembl chr 6:19,891,107...19,912,913 		JBrowse link
G MMP2 matrix metallopeptidase 2 treatment ISO protein:increased expression:mammary gland
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:19725228 PMID:23359979 PMID:28574600 RGD:2325823 RGD:8657038 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MMP7 matrix metallopeptidase 7 onset ISO RGD PMID:9850086 RGD:9685350 NCBI chr 9:33,214,590...33,225,080
Ensembl chr 9:33,214,594...33,225,080 		JBrowse link
G MMP9 matrix metallopeptidase 9 treatment ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:mammary gland		 CTD
RGD		 PMID:19725228 PMID:21283680 PMID:23359979 RGD:2325823 RGD:8657038 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
G MPZL1 myelin protein zero like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:83,235,712...83,309,620
Ensembl chr 4:83,235,714...83,316,405 		JBrowse link
G MRC2 mannose receptor C-type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:16,059,759...16,119,571
Ensembl chr12:16,059,768...16,119,571 		JBrowse link
G MT-CO1 mitochondrially encoded cytochrome c oxidase I ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr MT:6,511...8,055
Ensembl chr MT:6,511...8,055 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:22349822 RGD:10040957 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MUC1 mucin 1, cell surface associated treatment ISO RGD PMID:23015160 RGD:7349374 NCBI chr 4:94,626,317...94,631,194 JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22384017 RGD:7240549 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NCOA1 nuclear receptor coactivator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21080969 NCBI chr 3:113,997,214...114,251,080
Ensembl chr 3:113,999,253...114,250,298 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO RGD PMID:22072621 RGD:10412719 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NOTCH4 notch receptor 4 ISO RGD PMID:15531924 RGD:2299154 NCBI chr 7:24,231,293...24,256,281
Ensembl chr 7:24,231,293...24,256,281 		JBrowse link
G NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462
G NUDT1 nudix hydrolase 1 ISO mRNA:increased expression:mammary gland RGD PMID:12036445 RGD:724605 NCBI chr 3:1,567,417...1,575,801
Ensembl chr 3:1,566,915...1,576,234 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:8647655 PMID:15089975 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546 		JBrowse link
G PADI4 peptidyl arginine deiminase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:75,935,909...75,966,275
Ensembl chr 6:75,935,889...75,966,293 		JBrowse link
G PAK4 p21 (RAC1) activated kinase 4 ISO RGD PMID:20697354 RGD:7775027 NCBI chr 6:47,869,604...47,914,185
Ensembl chr 6:47,869,577...47,914,182 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 treatment ISO RGD PMID:23404339 RGD:10053670 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G PCNA proliferating cell nuclear antigen ISO mRNA,protein:increased expression:mammary gland: RGD PMID:2567593 RGD:10448972 NCBI chr17:14,137,746...14,142,584
Ensembl chr17:14,136,886...14,142,744 		JBrowse link
G PCP4 Purkinje cell protein 4 ISO mRNA,protein:increased expression:cytoplasm: RGD PMID:19480007 RGD:9850273 NCBI chr13:203,412,479...203,479,216
Ensembl chr13:203,412,479...203,479,209 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)
mRNA, protein:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:12376462 PMID:16316942 RGD:2292404 RGD:2306898 NCBI chr 3:296,399...322,967
Ensembl chr 3:301,584...321,712 		JBrowse link
G PEBP1 phosphatidylethanolamine binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:34,523,901...34,530,238 JBrowse link
G PGAM1 phosphoglycerate mutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:108,822,782...108,832,818
Ensembl chr14:108,822,812...108,833,058 		JBrowse link
G PGR progesterone receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15637090 NCBI chr 9:32,035,684...32,129,776
Ensembl chr 9:32,035,684...32,129,221 		JBrowse link
G PHB1 prohibitin 1 ISO mRNA, protein:increased expression:mammary gland
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12376462 RGD:2292404 NCBI chr12:25,596,520...25,609,693
Ensembl chr12:25,596,523...25,609,706 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:22064478 RGD:8693420 NCBI chr 2:68,715,898...68,729,471
Ensembl chr 2:68,715,880...68,729,870 		JBrowse link
G PKM pyruvate kinase M1/2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:60,971,807...61,032,780
Ensembl chr 7:60,975,667...61,004,316
Ensembl chr 7:60,975,667...61,004,316 		JBrowse link
G PLAU plasminogen activator, urokinase disease_progression ISO RGD PMID:18052026 RGD:6484140 NCBI chr14:76,629,313...76,635,173
Ensembl chr14:76,629,299...76,635,172 		JBrowse link
G PLK2 polo like kinase 2 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:12376462 RGD:2292404 NCBI chr16:37,299,116...37,305,114
Ensembl chr16:37,299,119...37,305,114 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:11137312 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PRDX2 peroxiredoxin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 2:66,207,829...66,211,474
Ensembl chr 2:66,207,828...66,212,009 		JBrowse link
G PRL prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
G PRLR prolactin receptor ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:16316942 RGD:2306898 NCBI chr16:20,637,568...20,655,881
Ensembl chr16:20,618,875...20,810,140 		JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:47,440,576...47,448,599
Ensembl chr 7:47,434,919...47,448,891 		JBrowse link
G PSME1 proteasome activator subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 7:75,161,830...75,164,531
Ensembl chr 7:75,160,766...75,164,810 		JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:77,551,562...77,563,153
Ensembl chr 2:77,551,562...77,563,134 		JBrowse link
G PTEN phosphatase and tensin homolog onset ISO RGD PMID:18381417 RGD:2292496 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTGER1 prostaglandin E receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11751431 NCBI chr 2:64,796,944...64,800,199
Ensembl chr 2:64,797,216...64,800,458 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO mRNA:increased expression:breast RGD PMID:18279516 PMID:18676768 PMID:21623034 RGD:2300118 RGD:2300130 RGD:5135030 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G PTK2 protein tyrosine kinase 2 disease_progression ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:15930288 PMID:18056629 PMID:24809783 RGD:2292554 RGD:2292560 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G PTN pleiotrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,787...12,309,044 		JBrowse link
G PTPRB protein tyrosine phosphatase receptor type B treatment ISO RGD PMID:23899555 RGD:151660352 NCBI chr 5:34,656,460...34,794,838
Ensembl chr 5:34,659,964...34,794,289 		JBrowse link
G RAN RAN, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr14:24,312,810...24,318,024
Ensembl chr14:24,311,577...24,317,789 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,450 		JBrowse link
G RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12606953 NCBI chr 2:89,525,948...89,794,103
Ensembl chr 2:89,528,111...89,790,719 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14522882 NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G RBP1 retinol binding protein 1 ISO CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:12376462 RGD:2292404 NCBI chr13:80,380,958...80,407,328
Ensembl chr13:80,380,962...80,407,458 		JBrowse link
G RBP4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:16316942 RGD:2306898 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
G RCN1 reticulocalbin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 2:28,696,528...28,714,083
Ensembl chr 2:28,696,661...28,709,672 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:decreased expression:peritoneal macrophage RGD PMID:16288051 RGD:2298764 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RELB RELB proto-oncogene, NF-kB subunit ISO RGD PMID:16260626 RGD:7777148 NCBI chr 6:51,444,670...51,480,350
Ensembl chr 6:51,444,664...51,480,319 		JBrowse link
G RNPEP arginyl aminopeptidase ISO protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:16619500 RGD:1582109 NCBI chr10:24,218,144...24,235,520
Ensembl chr10:24,218,139...24,235,518 		JBrowse link
G RPL3 ribosomal protein L3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 5:8,922,697...8,929,768
Ensembl chr 5:8,922,665...8,929,767 		JBrowse link
G RPL6 ribosomal protein L6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:39,302,447...39,309,239
Ensembl chr14:39,303,350...39,309,236 		JBrowse link
G RPS14 ribosomal protein S14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 2:151,430,047...151,433,951
Ensembl chr 2:151,430,049...151,433,856 		JBrowse link
G RUNX1 RUNX family transcription factor 1 ISO mRNA:increased expression:mammary gland RGD PMID:29435983 RGD:126779584 NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,837...198,638,189 		JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:16344269 RGD:1643109 NCBI chr 1:273,698,842...273,797,622
Ensembl chr 1:273,705,505...273,797,620 		JBrowse link
G S100A6 S100 calcium binding protein A6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:96,098,264...96,099,686
Ensembl chr 4:96,098,525...96,099,684 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 4:117,064,632...117,069,724
Ensembl chr 4:117,064,755...117,069,650 		JBrowse link
G SCARB1 scavenger receptor class B member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
G SCD stearoyl-CoA desaturase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr14:111,461,560...111,478,033
Ensembl chr14:111,461,569...111,478,020 		JBrowse link
G SELENOP selenoprotein P ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr16:27,537,885...27,547,863
Ensembl chr16:27,537,885...27,631,130 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 1:29,625,786...29,753,619
Ensembl chr 1:29,745,114...29,753,602 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 2:131,016,430...131,109,307
Ensembl chr 2:131,016,418...131,109,299 		JBrowse link
G SLC25A10 solute carrier family 25 member 10 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr12:1,191,242...1,197,439
Ensembl chr12:1,189,903...1,197,301 		JBrowse link
G SNCG synuclein gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:87,916,353...87,922,111
Ensembl chr14:87,904,659...87,922,095 		JBrowse link
G SNRPD3 small nuclear ribonucleoprotein D3 polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr14:49,585,177...49,598,015 JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO mRNA:increased expression:mammary gland RGD PMID:18381452 PMID:20354188 RGD:21079418 RGD:2298899 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO mRNA:increased expression:mammary gland RGD PMID:18381452 RGD:2298899 NCBI chr12:3,643,832...3,647,015
Ensembl chr12:3,643,929...3,647,009 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23964924 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G SOX9 SRY-box transcription factor 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G SPINT2 serine peptidase inhibitor, Kunitz type 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 6:47,181,772...47,210,564
Ensembl chr 6:47,181,768...47,210,559 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:15318939 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr12:4,800,578...4,803,767
Ensembl chr12:4,800,624...4,801,675 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:11325527 RGD:2291895 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism
mRNA:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:16316942 PMID:17483332 RGD:2291914 RGD:2306898 NCBI chr12:20,407,316...20,471,091
Ensembl chr12:20,407,233...20,472,992 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A susceptibility ISO CTD Direct Evidence: marker/mechanism
protein:altered localization:nucleus
protein:increased tyrosine phosphorylation:mammary gland
mRNA:increased expression:mammary gland (rat)
mRNA, protein:increased expression:mammary gland (rat)		 CTD
RGD		 PMID:12082622 PMID:12376462 PMID:15609129 PMID:16316942 PMID:17173897 More... RGD:151665819 RGD:2291927 RGD:2291932 RGD:2292404 RGD:2298539 RGD:2306898 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 ISO DNA:gene knockout::Balb/C-derived Stat6(-/-) mice resistant to growth of implanted Balb/C mammary tumors RGD PMID:11086031 RGD:2298563 NCBI chr 5:22,406,356...22,422,412
Ensembl chr 5:22,406,368...22,421,989 		JBrowse link
G STC2 stanniocalcin 2 ISO mRNA:increased expression:mammary gland RGD PMID:18959458 RGD:2313895 NCBI chr16:50,989,676...51,001,412
Ensembl chr16:50,989,433...51,004,481 		JBrowse link
G STMN1 stathmin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 6:83,356,404...83,362,546
Ensembl chr 6:83,356,412...83,362,500 		JBrowse link
G TDG thymine DNA glycosylase ISO mRNA:increased expression:mammary gland tumor (mouse) RGD PMID:9794235 RGD:2317355 NCBI chr 5:80,473,233...80,492,295
Ensembl chr 5:80,473,234...80,492,287 		JBrowse link
G TF transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9879772 PMID:16316942 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TFF1 trefoil factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680 NCBI chr13:205,687,558...205,691,512
Ensembl chr13:205,687,560...205,691,460 		JBrowse link
G TGFA transforming growth factor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:8603490 NCBI chr 3:71,948,232...72,054,257
Ensembl chr 3:71,948,137...72,050,474 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO RGD PMID:8466857 RGD:7394797 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:12808151 RGD:737735 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO RGD PMID:12808151 RGD:737735 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
G THBS1 thrombospondin 1 ISO mRNA:increased expression:mammary gland RGD PMID:15459484 RGD:1626167 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
G THRSP thyroid hormone responsive ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 9:12,479,913...12,484,323
Ensembl chr 9:12,479,907...12,488,557 		JBrowse link
G TKT transketolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr13:35,348,921...35,377,518
Ensembl chr13:35,348,915...35,377,587 		JBrowse link
G TLE4 TLE family member 4, transcriptional corepressor ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 1:232,355,959...232,504,766
Ensembl chr 1:232,355,959...232,504,763 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:19755514 RGD:7401185 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO CTD Direct Evidence: therapeutic CTD PMID:21252285 NCBI chr13:111,021,952...111,103,060
Ensembl chr13:110,983,298...111,038,324 		JBrowse link
G TP53 tumor protein p53 disease_progression ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:17470299 PMID:18092324 PMID:24809783 RGD:2290539 RGD:2290577 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G TPM3 tropomyosin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 PMID:16316942 NCBI chr 4:95,542,329...95,572,946
Ensembl chr 4:95,542,473...95,572,938 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 4:22,905,627...23,162,862
Ensembl chr 4:22,905,637...23,159,546 		JBrowse link
G TSC22D1 TSC22 domain family member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr11:22,518,792...22,634,411
Ensembl chr11:22,518,795...22,634,407 		JBrowse link
G TXNIP thioredoxin interacting protein severity ISO mRNA:decreased expression:mammary gland RGD PMID:15170812 RGD:1642758 NCBI chr 4:99,348,589...99,351,760
Ensembl chr 4:99,348,490...99,352,755 		JBrowse link
G TYMS thymidylate synthetase ISO RGD PMID:9635926 RGD:2315839 NCBI chr 6:105,642,730...105,660,279
Ensembl chr 6:105,642,381...105,660,578 		JBrowse link
G UBE2I ubiquitin conjugating enzyme E2 I ISO MCF-7 human breast cancer cell tumors grown in nude mice
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:15735760 PMID:16316942 RGD:2301345 NCBI chr 3:40,556,556...40,586,382 JBrowse link
G UCP2 uncoupling protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,358,025...8,365,547 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16316942 NCBI chr 3:59,187,900...59,193,165
Ensembl chr 3:59,185,735...59,193,128 		JBrowse link
G VDR vitamin D receptor ISO RGD PMID:15333467 RGD:8158073 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,266,475 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment ISO human protein in a mouse model RGD PMID:21890879 RGD:6771361 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,366 		JBrowse link
G WNT1 Wnt family member 1 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr 5:15,010,607...15,015,007
Ensembl chr 5:15,010,786...15,014,998 		JBrowse link
G WNT2 Wnt family member 2 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr18:28,945,825...28,993,969
Ensembl chr18:28,946,326...28,993,961 		JBrowse link
G WNT3 Wnt family member 3 ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:9419423 RGD:2298848 NCBI chr12:17,627,291...17,681,197
Ensembl chr12:17,628,726...17,681,026 		JBrowse link
G WNT3A Wnt family member 3A ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,153,970...51,202,176 		JBrowse link
G WNT5B Wnt family member 5B no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr 5:68,627,158...68,731,938
Ensembl chr 5:68,627,185...68,732,265 		JBrowse link
G WNT6 Wnt family member 6 no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr15:120,901,471...120,917,359
Ensembl chr15:120,901,376...120,917,486 		JBrowse link
G WNT7A Wnt family member 7A ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr13:70,538,802...70,602,464
Ensembl chr13:70,538,894...70,602,454 		JBrowse link
G WNT7B Wnt family member 7B no_association ISO in vitro transformation of transfected C57MG mammary epithelial cell line RGD PMID:8065359 PMID:9419423 RGD:2298848 RGD:2298863 NCBI chr 5:3,521,412...3,572,322
Ensembl chr 5:3,521,288...3,572,314 		JBrowse link
G XDH xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 3:107,987,060...108,052,043
Ensembl chr 3:107,987,126...108,053,169 		JBrowse link
G XIAP X-linked inhibitor of apoptosis ISO CTD Direct Evidence: therapeutic CTD PMID:12766084 NCBI chr  X:101,399,374...101,440,021
Ensembl chr  X:101,399,812...101,440,013 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283680
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:12376462 NCBI chr 4:35,975,513...36,009,909
Ensembl chr 4:35,975,508...36,009,887 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15392
    disease of cellular proliferation 7397
      Experimental Neoplasms 475
        Experimental Mammary Neoplasms 282
Path 2
Term Annotations click to browse term
  disease 15392
    Pathological Conditions, Signs and Symptoms 12067
      Signs and Symptoms 10094
        Neurologic Manifestations 9793
          sensory system disease 6893
            skin disease 4050
              breast disease 1421
                Breast Neoplasms 1408
                  Animal Mammary Neoplasms 305
                    Experimental Mammary Neoplasms 282
paths to the root