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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Facial Nerve Injuries
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Accession:DOID:9004001 term browser browse the term
Definition:Traumatic injuries to the facial nerve. This may result in FACIAL PARALYSIS, decreased lacrimation and salivation, and loss of taste sensation in the anterior tongue. The nerve may regenerate and reform its original pattern of innervation, or regenerate aberrantly, resulting in inappropriate lacrimation in response to gustatory stimuli (e.g., 'crocodile tears') and other syndromes.
Synonyms:exact_synonym: Cranial Nerve VII Injuries;   Facial Nerve Avulsion;   Facial Nerve Avulsions;   Facial Nerve Injury;   Facial Nerve Trauma;   Facial Nerve Traumas;   Seventh Cranial Nerve Injuries;   Traumatic Facial Neuropathies;   Traumatic Facial Neuropathy
 primary_id: MESH:D020220;   RDO:0007357

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Facial Nerve Injuries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:19427307 RGD:2325258 NCBI chrNW_004936672:3,461,387...3,468,053
Ensembl chrNW_004936672:3,460,383...3,468,255 		JBrowse link
G Atf2 activating transcription factor 2 ISO RGD PMID:9813301 RGD:10047413 NCBI chrNW_004936509:4,729,984...4,826,367
Ensembl chrNW_004936509:4,732,930...4,826,443 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 ISO RGD PMID:19922414 RGD:6892922 NCBI chrNW_004936596:223,660...224,739
Ensembl chrNW_004936596:223,660...224,739 		JBrowse link
G Cd59 CD59 molecule (CD59 blood group) ISO mRNA, protein:increased expression:facial VII nucleus RGD PMID:9846834 RGD:1600495 NCBI chrNW_004936533:4,242,589...4,263,136 JBrowse link
G Clu clusterin ISO protein:increased expression:neuron,astrocyte RGD PMID:10800205 RGD:408418725 NCBI chrNW_004936675:499,745...513,515
Ensembl chrNW_004936675:499,199...513,836 		JBrowse link
G Csf1 colony stimulating factor 1 ISO protein:increased expression:facial VII nerve, microglial cell RGD PMID:20831658 RGD:5131509 NCBI chrNW_004936704:1,372,137...1,393,355
Ensembl chrNW_004936704:1,378,103...1,393,542 		JBrowse link
G Ctss cathepsin S ISO RGD PMID:17539023 RGD:5686912 NCBI chrNW_004936580:963,176...991,732
Ensembl chrNW_004936580:963,153...991,442 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chrNW_004936486:6,066,108...6,262,055
Ensembl chrNW_004936486:6,071,023...6,262,165 		JBrowse link
G Hgf hepatocyte growth factor treatment ISO RGD PMID:21562589 RGD:8548634 NCBI chrNW_004936734:354,798...428,356
Ensembl chrNW_004936734:356,115...428,779 		JBrowse link
G Mt3 metallothionein 3 treatment ISO RGD PMID:14625437 RGD:9685806 NCBI chrNW_004936475:8,864,512...8,866,516
Ensembl chrNW_004936475:8,864,675...8,866,506 		JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 ISO mRNA:increased expression:skeletal muscle RGD PMID:8875451 RGD:2302319 NCBI chrNW_004936605:1,915,246...1,928,853
Ensembl chrNW_004936605:1,915,031...1,928,732 		JBrowse link
G Ret ret proto-oncogene ISO mRNA:increased expression:facial VII nucleus RGD PMID:9582449 RGD:6218984 NCBI chrNW_004936617:2,927,185...2,980,594
Ensembl chrNW_004936617:2,927,155...2,980,602 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14615
    sensory system disease 6651
      mouth disease 954
        facial nerve disease 53
          Facial Nerve Injuries 12
Path 2
Term Annotations click to browse term
  disease 14615
    disease of anatomical entity 14320
      nervous system disease 12594
        peripheral nervous system disease 4035
          neuropathy 3853
            cranial nerve disease 658
              facial nerve disease 53
                Facial Nerve Injuries 12
paths to the root