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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:mood disorder
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Accession:DOID:3324 term browser browse the term
Definition:A cognitive disorder that involves a disturbance in mood as the predominant underlying feature. (DO)
Synonyms:exact_synonym: affective disorder;   affective disorders;   episodic mood disorder;   mood disorders
 primary_id: MESH:D019964
 xref: EFO:0004247;   ICD10CM:F39;   NCI:C92200
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
mood disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy8 adenylate cyclase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19691954 NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911 		JBrowse link
G Adcy9 adenylate cyclase 9 no_association ISO DNA:polymorphisms:repeat,cds: RGD PMID:11840511 RGD:1358365 NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:29987918 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B no_association ISO DNA:SNP: :rs28373064, 35369693, rs28632197 (human)
DNA:SNP: :rs28536160 (human)		 RGD PMID:23962971 PMID:23962971 RGD:11528373, RGD:11528373 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment ISO RGD PMID:34078872 RGD:405850253 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G C3 complement C3 ISO RGD PMID:17321106 RGD:408418723 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Dctn1 dynactin subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19136952 NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IMP RGD PMID:22884333 RGD:9686419 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29921868 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit ISO
ISS		 MouseDO
RGD		 PMID:16619054 RGD:8694301 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Rara retinoic acid receptor, alpha ISO RGD PMID:19596122 RGD:2314250 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19878141 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Sst somatostatin ISO CTD Direct Evidence: marker/mechanism CTD PMID:25600109 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
bipolar disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEA GAD PMID:15118671 RGD:1331525 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adcy2 adenylate cyclase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236 		JBrowse link
G Add3 adducin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:plasma RGD PMID:22137759 RGD:5686381 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Agt angiotensinogen ISO GAD PMID:15118671 RGD:1331525 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akap11 A-kinase anchoring protein 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35410376 NCBI chr15:53,911,635...53,956,138
Ensembl chr15:53,911,657...53,941,605 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO DNA:SNP, haplotype: :multiple (human) RGD PMID:20214684 RGD:5509071 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ank3 ankyrin 3 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNS:SNPs:multiple:(human)		 CTD
RGD		 PMID:18711365 PMID:21926974 PMID:31043756 PMID:33729739 RGD:153344594 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 ISO
ISS		 MouseDO
RGD		 PMID:9646882 RGD:1358437 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO DNA:SNP: :rs28536160 (human) RGD PMID:24012103 RGD:14700651 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 PMID:19018715 PMID:15118671 RGD:1331525 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25395965 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 sexual_dimorphism ISO associated with Alcohol-related disorders;DNA:SNP::(rs11600996) (Human) RGD PMID:30121446 RGD:405866353 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Brd1 bromodomain containing 1 susceptibility ISO DNA,SNP,haplotype:3'UTR: RGD PMID:16924267 RGD:9586096 NCBI chr 7:119,774,187...119,822,032
Ensembl chr 7:119,774,188...119,822,031 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18711365 PMID:21926972 PMID:21926974 PMID:31043756 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D ISO CTD Direct Evidence: marker/mechanism CTD PMID:28194001 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISS MouseDO NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ISO RGD PMID:15034225 RGD:1358456 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cd47 Cd47 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cdc42 cell division cycle 42 ISO RGD PMID:18391128 RGD:5688274 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP: :rs324650 (human)
protein:decreased expression:cerebral cortex		 RGD PMID:20351719 PMID:19103464 RGD:5509579, RGD:5509584 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit susceptibility ISO DNA:SNPs: : rs4952,rs4953 (human) RGD PMID:21191315 RGD:405849396 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Clock clock circadian regulator ISS MouseDO NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism
DNA:promoter:Hypomethylation		 CTD
RGD		 PMID:11772685 PMID:16984965 RGD:401940146 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cplx1 complexin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:1,184,677...1,216,392 JBrowse link
G Cplx2 complexin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Cs citrate synthase treatment IEP protein decreased expression:prefrontal cortex
protein decreased expression:brain		 RGD PMID:20372980 PMID:17367908 PMID:24359811 RGD:329337348, RGD:329337351, RGD:329337349 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Ddc dopa decarboxylase ISO DNA:deletions:5' utr, intron:g.-601delG, g.722_725delGAGA (human) RGD PMID:12555230 RGD:1358586 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Disc1 DISC1 scaffold protein susceptibility ISO DNA;SNPs: :rs2738864,rs16841582 (human)
DNA:SNPs: :rs1538979, rs821577, rs821633 (human)
DNA:SNPs: :multiple		 RGD PMID:21222298 PMID:18317464 PMID:15386212 RGD:5509829, RGD:5509836, RGD:5509833 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dixdc1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19153942 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd5 dopamine receptor D5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 IEP RGD PMID:34189720 RGD:405650687 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Fads2 fatty acid desaturase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fstl5 follistatin-like 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:160,857,989...161,526,589
Ensembl chr 2:160,856,291...161,526,589 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 ISO DNA:repeat:intron:IVS8CA (human) RGD PMID:11840313 RGD:1358391 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 ISO RGD PMID:9514592 RGD:1358630 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917 		JBrowse link
G Gad1 glutamate decarboxylase 1 ISO protein:decreased expression:prefrontal cortex layers 2-5 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15560956 PMID:18534564 RGD:6480428 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15560956 PMID:34189720 RGD:405650687 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gch1 GTP cyclohydrolase 1 ISO DNA:polymorphism RGD PMID:15909293 RGD:1601281 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18332879 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ISO DNA:repeat:promoter:(GT)18-33 (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:31043756 PMID:12809987 RGD:1358644 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:16549338 RGD:1642201 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO mRNA, protein:decreased expression:frontal cortex (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12808434 PMID:19400979 RGD:5685029 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Grn granulin precursor ISO protein:decreased expression:plasma RGD PMID:24581833 RGD:10401641 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20357757 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20357757 PMID:17357145 PMID:16397405 RGD:1641929, RGD:1641931 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IEA
ISO		 CTD Direct Evidence: marker/mechanism CTD PMID:14708030 PMID:15118671 RGD:1331525 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C ISO DNA:missense mutation:cds:p.C23S (human) RGD PMID:8823764 RGD:1358737 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Impa2 inositol monophosphatase 2 susceptibility ISO DNA:SNPs:promoter:-461C>T, -207T>C(human) RGD PMID:9322233 PMID:11673796 PMID:14699425 RGD:6480265, RGD:6480269, RGD:6480267 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641 		JBrowse link
G Ins2 insulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:5506046 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363 		JBrowse link
G Kat6b lysine acetyltransferase 6B ISO DNA:mutations:multiple (human) RGD PMID:24444492 RGD:9588521 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316 		JBrowse link
G L1cam L1 cell adhesion molecule ISO associated with Depressive Disorder; mRNA:increased expression:blood (human) RGD PMID:18430502 RGD:6483084 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Lman2l lectin, mannose-binding 2-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 9:38,661,709...38,685,244
Ensembl chr 9:38,661,712...38,685,337 		JBrowse link
G Mbl2 mannose binding lectin 2 susceptibility ISO DNA:haplotype: : RGD PMID:24856568 RGD:12910826 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:68,596,729...68,605,547
Ensembl chr 4:68,596,729...68,605,428 		JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 ISO DNA:missense mutation:cds:m.3644T>C (human) RGD PMID:15533721 RGD:5490261 NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17074966 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 ISO DNA:snps:introns:IVS6+32T>C, IVS7+11G>C, IVS12+21C>A (human) RGD PMID:15050861 RGD:1358750 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ncan neurocan ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:20368511 RGD:6484696 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19135101 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Ngf nerve growth factor sexual_dimorphism ISO DNA:SNPs,haplotypes: :multiple RGD PMID:21294249 RGD:401965386 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrg1 neuregulin 1 ISO
IEP		 DNA:SNP:enhancer: (rs35753505) RGD PMID:18585932 PMID:34189720 RGD:39131291, RGD:405650687 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntng1 netrin G1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17507910 NCBI chr 2:197,462,785...197,827,681
Ensembl chr 2:197,463,945...197,826,997 		JBrowse link
G Ntng2 netrin G2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17507910 NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO protein:decreased expression:cerebellum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19018715 PMID:21612826 RGD:5684549 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473 		JBrowse link
G Pc pyruvate carboxylase ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380 		JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18394866 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Per3 period circadian regulator 3 sexual_dimorphism ISO associated with Alcohol-Related Disorders; DNA:SNP::(rs228642) (Human) RGD PMID:30121446 RGD:405866353 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Plekho1 pleckstrin homology domain containing O1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:183,544,487...183,552,928
Ensembl chr 2:183,544,499...183,552,785 		JBrowse link
G Polg DNA polymerase gamma, catalytic subunit ISS MouseDO NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2843795 PMID:9664777 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B ISO DNA, mRNA:SNPs, haplotype, splice variant:multiple RGD PMID:23295814 RGD:13515076 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO mRNA, protein:decreased expression:prefrontal cortex RGD PMID:20038946 RGD:5688160 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO mRNA, protein:increased expression:prefrontal cortex RGD PMID:20038946 RGD:5688160 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pvalb parvalbumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein ISO mRNA, protein:increased expression:dorsolateral prefrontal cortex (human) RGD PMID:16687443 RGD:5490162 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253 		JBrowse link
G Reln reelin ISO protein:decreased expression:hippocampus (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11126396 PMID:14708030 PMID:15560956 PMID:11126396 RGD:2324681 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
G RT1-Da RT1 class II, locus Da ISO RGD PMID:16687443 RGD:5490162 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G S100b S100 calcium binding protein B IEP
ISO		 protein:increased expression:cerebrospinal fluid
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15581912 PMID:16476148 PMID:15581912 RGD:5508853 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Serpina1 serpin family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17659342 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 ISO DNA:SNPs:5' utr, cds:g.-584A>G (rs988713), p.T136I (rs1390938) (human) RGD PMID:16936705 RGD:5131197 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc5a3 solute carrier family 5 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16420717 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism
DNA:repeats:promoter:		 CTD
RGD		 PMID:11772685 PMID:16395126 PMID:10484962 RGD:36947381 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Snca synuclein alpha ISO RGD PMID:19198857 RGD:6478716 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sp4 Sp4 transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19401786 NCBI chr 6:139,187,458...139,252,741
Ensembl chr 6:139,192,147...139,252,126 		JBrowse link
G Srpk2 SRSF protein kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:11,464,684...11,655,993
Ensembl chr 4:11,464,674...11,655,990 		JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 ISO mRNA:increased expression:peripheral blood mononuclear cell (human) RGD PMID:18281098 RGD:11039413 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078 		JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 2:22,650,488...22,938,669
Ensembl chr 2:22,651,258...22,933,696 		JBrowse link
G Sstr5 somatostatin receptor 5 ISO DNA:SNP, missense mutations, haplotype: :573G>A, p.L48M, p.P335L (human) RGD PMID:12192619 RGD:1358589 NCBI chr10:14,506,868...14,512,946
Ensembl chr10:14,506,868...14,512,946 		JBrowse link
G Stard9 StAR-related lipid transfer domain containing 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:107,581,097...107,672,746
Ensembl chr 3:107,581,164...107,673,898 		JBrowse link
G Stk4 serine/threonine kinase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 susceptibility ISO DNA:SNPs:promoter,intron: RGD PMID:28178086 RGD:13209005 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15845098 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19204064 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tenm4 teneurin transmembrane protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21926972 NCBI chr 1:149,895,097...151,263,315
Ensembl chr 1:150,780,381...151,259,144 		JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:40,460,814...40,899,583 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B ISO protein:increased expression:plasma RGD PMID:20861651 RGD:7205488 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO mRNA:increased expression:frontal association cortex
ClinVar Annotator: match by term: Bipolar affective disorder, susceptibility to		 ClinVar
RGD		 PMID:17905754 PMID:18347598 PMID:19319927 PMID:25741868 PMID:16240163 RGD:5686358 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 8:111,275,973...111,355,491
Ensembl chr 8:111,276,354...111,355,092 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23602965 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23602965 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:6455462 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Vwf von Willebrand factor ISO protein:increased expression:plasma RGD PMID:19839997 RGD:7207027 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr13:22,118,677...22,193,626
Ensembl chr13:22,119,568...22,166,373 		JBrowse link
G Zfp592 zinc finger protein 592 ISO CTD Direct Evidence: marker/mechanism CTD PMID:31043756 NCBI chr 1:134,951,286...135,002,443
Ensembl chr 1:134,967,783...135,002,443 		JBrowse link
depressive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:21914462 RGD:9588556 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO protein:increased expression, increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15108178 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:26860412 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A ISO RGD PMID:19540213 RGD:5688369 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra2a adrenoceptor alpha 2A IMP RGD PMID:20047711 RGD:6480482 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9029664 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d treatment IDA RGD PMID:25641667 RGD:13800885 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B treatment
no_association		 ISO
IMP		 associated with bipolar disorder;DNA:SNP: :multiple RGD PMID:26700241 PMID:24654684 PMID:23068076 RGD:14700672, RGD:14700666, RGD:14700671 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21308783 RGD:10054142 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP RGD PMID:21308783 RGD:10054142 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP
ISO		 protein:decreased expression:brain
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:decreased expression:lymphocyte, platelet		 CTD
RGD		 PMID:16330021 PMID:21945287 PMID:20920483 PMID:24128869 PMID:22097208 More... RGD:4891127, RGD:10059357, RGD:5684923, RGD:4891139 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 disease_progression
treatment		 ISO RGD PMID:25386878 PMID:25386878 RGD:11561930, RGD:11561930 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Cadm1 cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Cat catalase ISO associated with gastric adenocarcinoma; protein:decreased expression:blood serum (human) RGD PMID:31396300 RGD:126908003 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IDA RGD PMID:21682945 RGD:13782377 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 NOT IEP RGD PMID:21682945 RGD:13782377 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Chat choline O-acetyltransferase IEP
IMP		 mRNA:decreased expression:habenula: RGD PMID:28420875 PMID:28420875 RGD:151347550, RGD:151347550 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 IEP mRNA:increased expression:brain RGD PMID:20830301 RGD:5509587 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit IEP mRNA:decreased expression:habenula: RGD PMID:28420875 RGD:151347550 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit IEP
ISO		 mRNA:decreased expression:habenula: RGD PMID:28420875 PMID:28420875 RGD:151347550, RGD:151347550 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit IEP mRNA:decreased expression:habenula: RGD PMID:28420875 RGD:151347550 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18286196 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP
IDA		 protein:increased expression:nucleus accumbens RGD PMID:26762379 PMID:31257291 RGD:401959608, RGD:401960862 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone IEP
ISO		 mRNA:increased expression:paraventricular nucleus, dorsal raphe nucleus (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12438692 PMID:18698320 PMID:20860876 RGD:5147490 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein ISO
IEP		 DNA:snps:intron, 3' utr:g.10661T>C, g.16113T>C (human)
protein:increased expression:hippocampus, frontal cortex (rat)		 RGD PMID:14573312 PMID:19631474 RGD:1358530, RGD:5508785 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP RGD PMID:20860876 RGD:5147490 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IEP RGD PMID:20860876 RGD:5147490 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Crp C-reactive protein ISO associated with kidney failure, chronic; protein:increased expression:plasma RGD PMID:22972567 RGD:6904211 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9018096 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP protein:increased expression:liver RGD PMID:20595028 RGD:4892242 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IEP RGD PMID:20595028 RGD:4892242 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Dbh dopamine beta-hydroxylase IEP protein:decreased expression:frontal cortex (rat) RGD PMID:19120095 RGD:5129527 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Disc1 DISC1 scaffold protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:29643356 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dixdc1 DIX domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27752079 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha ISO mRNA:increased expression:nucleus accumbens: RGD PMID:20729844 RGD:9589061 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Drd1 dopamine receptor D1 IEP mRNA:increased expression:caudate putamen (rat) RGD PMID:17558292 RGD:2311588 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 ISO
IEP		 DNA:snp:cds:p.H313H (human)
mRNA:decreased expression:striatum		 RGD PMID:9513185 PMID:21596067 RGD:1358603, RGD:6907449 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd5 dopamine receptor D5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G Esr2 estrogen receptor 2 treatment IDA RGD PMID:24128867 RGD:10045672 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:30138765 RGD:13792497 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16861106 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16861106 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit treatment IEP RGD PMID:34431619 RGD:405650599 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO protein:decreased expression: hippocampus (human) RGD PMID:27494187 RGD:401851061 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fth1 ferritin heavy chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17063146 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17063146 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 ISO DNA:repeat:: (human) RGD PMID:9267853 RGD:1358629 NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917 		JBrowse link
G Gata1 GATA binding protein 1 ISO
IEP		 mRNA:increased expression:prefrontal cortex RGD PMID:22885997 PMID:25340772 PMID:22885997 RGD:6892958, RGD:11049534, RGD:6892958 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:25340772 RGD:11049534 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO DNA:SNP: :rs884344 RGD PMID:24022000 RGD:405849398 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272368 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Glo1 glyoxalase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22113448 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gnb3 G protein subunit beta 3 susceptibility ISO DNA:SNP:cds: 825C>T (human) RGD PMID:12634518 RGD:1358639 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO RGD PMID:23707456 RGD:11352766 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment IEP RGD PMID:33935736 RGD:401827871 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 treatment ISO RGD PMID:32048672 RGD:405849038 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20357757 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20357757 PMID:20534517 PMID:19815943 RGD:10045564 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hdac5 histone deacetylase 5 IEP protein:increased expression:hippocampus: RGD PMID:24495952 RGD:9681459 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO RGD PMID:21512427 PMID:10578452 RGD:5683629, RGD:5683634 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment IEA
IEP
IDA		 GAD
RGD		 PMID:15118671 PMID:18239281 PMID:30628811 RGD:1331525, RGD:401901207, RGD:401900757 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO RGD PMID:16487942 RGD:6480662 NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21859099 PMID:16828124 RGD:6482189 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO associated with alcohol dependence;protein:increased expression:plasma RGD PMID:26792039 RGD:401976547 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1b interleukin 1 beta IEP
ISO		 protein:increased expression:frontal cortex, hippocampus, hypothalamus (rat)
protein:increased expression:serum, hippocampus (mouse)
associated with gastric adenocarcinoma; protein:increased expression:blood serum (human)		 RGD PMID:15000880 PMID:31396300 PMID:31396300 RGD:1626681, RGD:126908003, RGD:126908003 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO associated with Status Epilepticus; rat model treated with human protein RGD PMID:22427156 RGD:7174694 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 treatment IEP
ISO		 mRNA:increased expression:colon
protein:increased expression:serum, hippocampus (mouse)
associated with gastric adenocarcinoma; protein:increased expression:blood serum (human)
associated with Chronic Hepatitis C; DNA:insertion/deletion:promoter:
associated with Hepatitis C, Chronic;DNA:SNP:promoter:-174G>C (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:hippocampus (rat)		 CTD
RGD		 PMID:18458677 PMID:23589140 PMID:31396300 PMID:31396300 PMID:23571152 More... RGD:10402829, RGD:126908003, RGD:126908003, RGD:38676480, RGD:14975286, RGD:11062144 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor IEP mRNA:increased expression:colon RGD PMID:23589140 RGD:10402829 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Ins1 insulin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:34352274 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IEP protein:increased expression:basolateral amygdala RGD PMID:10719210 RGD:2290593 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21871532 PMID:16906152 RGD:9831184 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kmo kynurenine 3-monooxygenase IEP protein:decreased activity:plasma RGD PMID:29217494 RGD:13703051 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881 		JBrowse link
G L1cam L1 cell adhesion molecule IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:20018220 RGD:6483073 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO RGD PMID:25386878 RGD:11561930 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO RGD PMID:21070506 RGD:401966883 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mc4r melanocortin 4 receptor treatment IMP associated with alcohol use disorder; associated with alcohol withdrawal syndrome RGD PMID:18499089 RGD:407572521 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719 		JBrowse link
G Mfn1 mitofusin 1 treatment ISO RGD PMID:22244747 RGD:13204844 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:22244747 RGD:13204844 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mif macrophage migration inhibitory factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20177408 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mir382 microRNA 382 treatment IEP RGD PMID:32982244 RGD:408364963 NCBI chr 6:128,748,539...128,748,618 JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease ISO ClinVar Annotator: match by term: Mental depression ClinVar PMID:25741868 PMID:26467025 PMID:26878173 PMID:26898890 PMID:27878467 More... NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II ISO protein:increased expression:blood serum, hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
NCBI chr MT:7,006...7,689
Ensembl chr MT:7,006...7,689 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:17074966 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 treatment IEP RGD PMID:29217494 RGD:13703051 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 susceptibility IEP RGD PMID:22311638 RGD:13801196 NCBI chr19:24,568,241...24,572,579
Ensembl chr19:24,568,241...24,572,579 		JBrowse link
G Nefl neurofilament light chain IEP protein:decreased expression:dentate gyrus, hippocampus CA3 RGD PMID:17683840 RGD:2299053 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO protein:increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngf nerve growth factor IEP mRNA:decreased expression:hippocampus RGD PMID:19129380 RGD:2303796 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor ISO DNA:SNP:CDS:p.S205L, minor (L) allele appears protective (human) RGD PMID:15274039 RGD:5508376 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nos1 nitric oxide synthase 1 treatment ISO
IDA		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17854383 PMID:20571741 RGD:13824995 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein treatment IDA RGD PMID:19587612 RGD:7327168 NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949 		JBrowse link
G Notch3 notch receptor 3 ISO ClinVar Annotator: match by term: Depression ClinVar PMID:15364702 PMID:16009764 PMID:21616505 PMID:28492532 PMID:32581362 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nppc natriuretic peptide C ISO DNA:SNP:CDS:multiple (human) RGD PMID:35642741 RGD:401854249 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Npy neuropeptide Y treatment ISO
IEP
IDA		 DNA:snp, missense mutation:promoter, cds:g.-399T>C, p.L7P (human)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:decreased expression:hippocampus, prefrontal cortex 		CTD
RGD		 PMID:9729278 PMID:17572454 PMID:14757324 PMID:22406386 PMID:19623606 RGD:1358535, RGD:10448940, RGD:10448937 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 treatment IMP
ISO
IDA		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9729278 PMID:17265460 PMID:19623606 PMID:21803058 RGD:1642308, RGD:10448937, RGD:10448284 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Npy2r neuropeptide Y receptor Y2 treatment IMP RGD PMID:21803058 RGD:10448284 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:28763303 RGD:13439713 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment
sexual_dimorphism 		IEP
IMP
ISO		 mRNA:decreased expression:hippocampus (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:14708030 PMID:21837980 PMID:27221032 PMID:31329100 PMID:32982244 RGD:5686290, RGD:408364988, RGD:407571699, RGD:408364963 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c1em1Kuan nuclear receptor subfamily 3, group C, member 1; CRISPR/Cas9 induced mutant1, Kuan sexual_dimorphism IMP RGD PMID:31329100 RGD:407571699
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO
IEP		 RGD PMID:20956301 PMID:22097208 RGD:5684782, RGD:5684923 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nts neurotensin ISO DNA:SNP:CDS:multiple (human) RGD PMID:35642741 RGD:401854249 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Ogdhl oxoglutarate dehydrogenase L ISO ClinVar Annotator: match by term: Depression ClinVar PMID:28017472 NCBI chr16:7,578,343...7,604,385
Ensembl chr16:7,578,367...7,604,386 		JBrowse link
G Oprk1 opioid receptor, kappa 1 severity ISO associated with alcohol use disorder;DNA:SNP: :rs963549 (human) RGD PMID:37177778 RGD:401850581 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Panx1 Pannexin 1 ISO DNA:SNP:CDS:multiple (human) RGD PMID:35642741 RGD:401854249 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP mRNA:decreased expression:striatum RGD PMID:21596067 RGD:6907449 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pde4d phosphodiesterase 4D IMP RGD PMID:22487514 RGD:7327149 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pdyn prodynorphin IMP RGD PMID:24816773 RGD:401850568 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO mRNA:increased expression:blood RGD PMID:22331023 RGD:6482716 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18201294 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272368 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B treatment IDA RGD PMID:27457507 RGD:13514054 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Prep prolyl endopeptidase IEP protein:altered activity:frontal cortex, striatum, hypothalamus (rat) RGD PMID:17415460 RGD:1626457 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466 		JBrowse link
G Prl prolactin ameliorates ISO associated with withdrawal disorder and alcohol dependence RGD PMID:3757769 RGD:401959379 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19356723 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Reln reelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Ren renin ISO Associated with hypertension;protein:decreased activity:blood (human) RGD PMID:29960014 RGD:125097507 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Rnf103 ring finger protein 103 IDA RGD PMID:11071867 RGD:634523 NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919 		JBrowse link
G S100a10 S100 calcium binding protein A10 IEP
ISO
IDA		 mRNA,protein:decreased expression:prefrontal cortex:
CTD Direct Evidence: marker/mechanism
DNA:hypermethylated:promoter:		 CTD
RGD		 PMID:21682946 PMID:21682946 PMID:21682946 RGD:9588311, RGD:9588311 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S100b S100 calcium binding protein B IEP protein:increased expression:hippocampus RGD PMID:21843601 RGD:5508824 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:25451969 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 ISO RGD PMID:17898223 RGD:5131168 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO mRNA:decreased expression:habenula: RGD PMID:28420875 RGD:151347550 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 IEP RGD PMID:18800064 RGD:6218960 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility
severity
treatment		 ISO
IMP		 associated with Pulmonary Disease, Chronic Obstructive;DNA:SNP: :rs3794808 (human)
associated with Chronic Hepatitis C; DNA:insertion/deletion:promoter:
associated with Coronary Disease;DNA:repeats:promoter:
associated with breast cancer;DNA:repeat:promoter:
DNA:hypomethylation:promoter
associated with Radiation Injuries;DNA:repeats:promoter:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12898347 PMID:18458677 PMID:18686203 PMID:21843009 PMID:20981038 More... RGD:4889426, RGD:38676480, RGD:38456010, RGD:36947877, RGD:36947869, RGD:36947395, RGD:36947387, RGD:4889509 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slc6a4m1Hubr solute carrier family 6 member 4; ZFN induced mutant1, Hubr IMP RGD PMID:18295409 RGD:4889509
G Snap25 synaptosome associated protein 25 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14708030 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Snca synuclein alpha IEP
ISO		 RGD PMID:18800064 PMID:19198857 RGD:6218960, RGD:6478716 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sncg synuclein, gamma IEP RGD PMID:18800064 RGD:6218960 NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19605942 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:hippocampus (mouse) RGD PMID:31396300 RGD:126908003 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stk33 serine/threonine kinase 33 ISO DNA:SNP:CDS:multiple (human) RGD PMID:35642741 RGD:401854249 NCBI chr 1:163,276,176...163,458,580
Ensembl chr 1:163,276,340...163,458,627 		JBrowse link
G Tg thyroglobulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:30373627 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Th tyrosine hydroxylase IEP mRNA,protein:decreased expression:hippocampus: RGD PMID:24495952 RGD:9681459 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO
IEP		 mRNA,protein:decreased expression:hippocampus:
DNA:SNPs, haplotype:intron:218A>C, 779A>C (human)		 RGD PMID:16165107 PMID:24495952 PMID:17134762 RGD:1580459, RGD:9681459, RGD:5686354 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17950541 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment IEP RGD PMID:32009956 RGD:127284856 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein IEP RGD PMID:22311638 RGD:13801196 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 ISO DNA:SNP:CDS:multiple (human) RGD PMID:35642741 RGD:401854249 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091 		JBrowse link
Major Affective Disorder 7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xbp1 X-box binding protein 1 susceptibility ISO ClinVar Annotator: match by term: Major affective disorder 7
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
major depressive disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy3 adenylate cyclase 3 ISS OMIM:608520 | OMIM:608691 MouseDO NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686 		JBrowse link
G Apoa1 apolipoprotein A1 susceptibility IEP protein: increased expression: cerebrospinal fluid RGD PMID:20580919 RGD:5128563 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 IEP protein:increased expression:blood serum (rat) RGD PMID:20580919 RGD:5128563 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Arrb1 arrestin, beta 1 severity ISO protein:decreased expression:blood, mononuclear cell RGD PMID:15514408 RGD:1578803 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:21803060 RGD:8655887 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C ISO CTD Direct Evidence: marker/mechanism CTD PMID:28696432 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Calm2 calmodulin 2 ISO mRNA:decreased expression:frontal association cortex RGD PMID:22885997 RGD:6892958 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Car1 carbonic anhydrase 1 ISS OMIM:608520 | OMIM:608691 MouseDO NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO DNA:SNP:3' utr:1890A>T (human)
protein:decreased expression:cerebral cortex		 RGD PMID:12116189 PMID:19103464 RGD:1358507, RGD:5509584 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit ISO mRNA:decreased expression:habenula: RGD PMID:28420875 RGD:151347550 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Cntnap2 contactin associated protein 2 susceptibility ISO DNA:SNPs: : rs2710102,rs2710117(human) RGD PMID:23123147 RGD:13450917 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23529111 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 ISS OMIM:608520 | OMIM:608691 MouseDO NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Ctnnd2 catenin delta 2 susceptibility ISO DNA:polymorphism:multiple (human) RGD PMID:24256404 RGD:40902831 NCBI chr 2:81,168,525...82,016,495
Ensembl chr 2:81,167,117...82,015,764 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 treatment ISO associated with alcoholic psychosis;DNA:polymorphism: :1846G.A (rs3892097)(human) RGD PMID:34117140 RGD:401901273 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Disc1 DISC1 scaffold protein susceptibility ISO DNA:SNP:Cds:p.S704C(human)
protein:altered expression:orbitofrontal cortex 		RGD PMID:16959794 PMID:15657124 RGD:5509832, RGD:5509834 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO mRNA:increased expression:dentated gyrus, hippocampus A1 RGD PMID:20953200 RGD:7771583 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B ISO protein:decreased expression:prefrontal cortex RGD PMID:21635931 RGD:11049139 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 susceptibility ISO associated with Trauma and Stressor Related Disorders; DNA:SNPs,haplotypes:multiple
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Major depressive disorder, increased recurrence of depressive episodes in, susceptibility to		 OMIM
CTD
ClinVar
RGD		 PMID:15565110 PMID:20090668 RGD:401976504 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Foxp2 forkhead box P2 no_association ISO DNA:SNP: :rs10447760 (human)
DNA:SNPs: :multiple		 RGD PMID:22404659 PMID:22404659 RGD:11535994, RGD:11535994 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Frem3 FRAS1 related extracellular matrix 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26441752 NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771 		JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15560956 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15560956 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gal galanin and GMAP prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Galr1 galanin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr18:75,772,021...75,787,577
Ensembl chr18:75,772,023...75,787,577 		JBrowse link
G Galr2 galanin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176 		JBrowse link
G Galr3 galanin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27940914 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685 		JBrowse link
G Gata1 GATA binding protein 1 ISO mRNA:increased expression:dorsolateral prefrontal cortex RGD PMID:22885997 RGD:6892958 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO DNA:SNP: :rs1043618 (human) RGD PMID:17428599 RGD:5147598 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO DNA:SNPs: :rs2075799, rs2227956 (human) RGD PMID:17428599 RGD:5147598 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B sexual_dimorphism
susceptibility		 ISO associated with attention deficit hyperactivity disorder;DNA:SNP: :rs11568817(human)
associated with disease of mental health; DNA:SNP: :861G>C(human)		 RGD PMID:28923721 PMID:12496953 RGD:405650695, RGD:405818271 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IDA mRNA:increased editing RGD PMID:16005997 RGD:1624993 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Ifi44l interferon-induced protein 44-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Il10 interleukin 10 ISO associated with Hepatitis C, Chronic;DNA:SNPs, haplotype:promoter:-592C>A, -���819C>T, -1082G>A (human) RGD PMID:30734130 RGD:14975122 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il2 interleukin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12635532 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il3 interleukin 3 ISO mRNA: increased expression: BA10: frontal cortex RGD PMID:20479761 RGD:5686897 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il5 interleukin 5 ISO protein: increased expression: serum RGD PMID:22230487 RGD:5687135 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 ISO associated with Hepatitis C, Chronic;DNA:SNP, haplotype:promoter:-174G>C (human) RGD PMID:30734130 RGD:14975122 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mc1r melanocortin 1 receptor ISO DNA:SNP:cds: rs885479,R163Q RGD PMID:21052032 RGD:5687198 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Med12 mediator complex subunit 12 ISO DNA:mutation:multiple RGD PMID:12216017 RGD:1358728 NCBI chr  X:66,404,807...66,427,775
Ensembl chr  X:66,404,760...66,428,387 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nos1 nitric oxide synthase 1 IEP RGD PMID:25001963 RGD:13825137 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO DNA:SNP:intron:IVS2+646C>G (human) RGD PMID:18246526 RGD:7174717 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29175309 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nrg1 neuregulin 1 ISO mRNA:increased expression:prefrontal cortex RGD PMID:29295823 RGD:41404730 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 severity ISO mRNA:decreased expression:depression
DNA:SNPs: :rs2289657, rs56142442 (human)
DNA:SNPs: : (human)		 RGD PMID:21223646 PMID:19844206 PMID:20124106 RGD:5684778, RGD:5684911, RGD:5684909 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Pawr pro-apoptotic WT1 regulator ISO protein:decreased expression:brain: RGD PMID:20067857 RGD:9835359 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pdyn prodynorphin ISO mRNA:decreased expression:periamygdaloid cortex
associated with heroin dependence or alcohol use disorder;DNA:repeat:promoter:rs35286251 (human)		 RGD PMID:24231353 PMID:35271823 RGD:401850554, RGD:401850556 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pten phosphatase and tensin homolog ISO protein:increased expression:occipital cortex (human) RGD PMID:12969265 RGD:127285604 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Reln reelin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11126396 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 ISO mRNA:decreased expression:habenula: RGD PMID:28420875 RGD:151347550 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 treatment
susceptibility
no_association		 ISO CTD Direct Evidence: marker/mechanism
DNA:repeats:promotor:
DNA:repeats:promoter:
DNA:hypomethylation:promoter:
DNA:SNPs, haplotypes:multiple		 CTD
RGD		 PMID:16055263 PMID:12955294 PMID:15812265 PMID:24679990 PMID:19844206 More... RGD:39128240, RGD:38456009, RGD:36947871, RGD:5684911, RGD:36947384, RGD:36947382 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Syn1 synapsin I ISO mRNA:decreased expression:dorsolateral prefrontal cortex RGD PMID:22885997 RGD:6892958 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Tac1 tachykinin, precursor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15845098 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tph2 tryptophan hydroxylase 2 susceptibility ISO ClinVar Annotator: match by term: Major depressive disorder
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:17905754 PMID:18347598 PMID:19319927 PMID:25741868 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
G Xdh xanthine dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20471444 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
melancholic depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disc1 DISC1 scaffold protein ISS OMIM:608516 MouseDO NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Hap1 huntingtin-associated protein 1 ISS OMIM:608516 MouseDO NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Morc1 MORC family CW-type zinc finger 1 ISS OMIM:608516 MouseDO NCBI chr11:52,178,769...52,384,255
Ensembl chr11:52,178,769...52,384,255 		JBrowse link
G Tph2 tryptophan hydroxylase 2 ISS OMIM:608516 MouseDO NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424 		JBrowse link
postpartum depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabrd gamma-aminobutyric acid type A receptor subunit delta ISS MouseDO NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411 		JBrowse link
G Il10 interleukin 10 IEP RGD PMID:17033197 RGD:1598630 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO RGD PMID:15544576 RGD:1580465 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
Vascular Depression term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26286041 RGD:11073724 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19099
    disease of anatomical entity 18440
      nervous system disease 14333
        central nervous system disease 12605
          brain disease 11834
            disease of mental health 8427
              cognitive disorder 2318
                mood disorder 303
                  atypical depressive disorder 0
                  bipolar disorder + 119
                  depressive disorder + 210
                  dysthymic disorder 0
paths to the root