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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:small cell carcinoma
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Accession:DOID:0050685 term browser browse the term
Definition:A carcinoma that is an undifferentiated neoplasm composed of primitive-appearing cells. (DO)
Synonyms:exact_synonym: SCCL;   SCLC;   SCLC1;   oat cell carcinoma;   oat cell carcinomas;   small cell carcinoma, intermediate cell;   small cell carcinomas
 narrow_synonym: Salivary Gland Small Cell Carcinoma
 primary_id: MESH:D018288
 alt_id: MIM:182280
 xref: EFO:0008524;   EFO:1000519;   ICDO:8041/3;   NCI:C4099


show annotations for term's descendants           Sort by:
small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIRC5 baculoviral IAP repeat containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15981204 NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215 		JBrowse link
G CHI3L1 chitinase 3 like 1 severity ISO protein:increased secretion:serum (human) RGD PMID:15541818 RGD:4892640 NCBI chr 9:113,885,541...113,895,033
Ensembl chr 9:113,885,542...113,895,131 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 ISO RGD PMID:20150622 RGD:5133439 NCBI chr14:51,818,625...52,363,662
Ensembl chr14:51,828,231...51,830,003 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 ISO protein:increased expression:lung (human) RGD PMID:24823637 RGD:151347636 NCBI chr12:22,466,386...22,562,320
Ensembl chr12:22,466,414...22,562,312 		JBrowse link
G IL6 interleukin 6 disease_progression ISO protein:increased expression:serum RGD PMID:20592377 RGD:4143263 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20946520 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G NPPA natriuretic peptide A ISO CTD Direct Evidence: therapeutic CTD PMID:18717826 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,918,845...71,921,405 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 susceptibility ISO DNA:SNP:exon:609C>T (human) RGD PMID:11679176 RGD:5135003 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590 		JBrowse link
G PYCARD PYD and CARD domain containing ISO CTD Direct Evidence: marker/mechanism CTD PMID:16778195 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,099...17,307,786 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO OMIM NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24658001 PMID:24658002 PMID:24658004 PMID:26343384 NCBI chr 2:69,717,175...69,810,301
Ensembl chr 2:69,662,238...69,810,295 		JBrowse link
G TERT telomerase reverse transcriptase susceptibility ISO DNA:SNP: :rs2736098(human) RGD PMID:24761905 RGD:150530628 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421 		JBrowse link
G TNF tumor necrosis factor severity ISO protein:decreased secretion:whole blood RGD PMID:8624296 RGD:4142840 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFSF10 TNF superfamily member 10 ISO RGD PMID:16313792 RGD:2312747 NCBI chr13:111,021,952...111,103,060
Ensembl chr13:110,983,298...111,038,324 		JBrowse link
G TP53 tumor protein p53 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17290066 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G WIF1 WNT inhibitory factor 1 ISO protein:decreased expression:lung RGD PMID:14517837 RGD:727214 NCBI chr 5:29,450,442...29,543,913
Ensembl chr 5:29,450,442...29,543,913 		JBrowse link
esophagus small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC110255312 keratin, type I cytoskeletal 14 ISO protein:increased expression:esophagus RGD PMID:16140947 RGD:1600174 NCBI chr12:21,074,965...21,079,393
Ensembl chr12:21,074,850...21,079,391 		JBrowse link
lung oat cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:26619011 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... NCBI chr14:99,929,590...100,021,619 JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1352883 PMID:7881418 PMID:9632788 PMID:9671401 PMID:10486322 More... NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Lung oat cell carcinoma ClinVar PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 PMID:1631151 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
lung small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1B activin A receptor type 1B ISO RGD PMID:33880365 RGD:151665493 NCBI chr 5:17,314,322...17,350,726
Ensembl chr 5:17,314,276...17,350,722 		JBrowse link
G ADCY1 adenylate cyclase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr18:50,043,572...50,143,549
Ensembl chr18:50,051,364...50,143,628 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO ClinVar Annotator: match by term: Small cell lung cancer ClinVar PMID:17611497 PMID:18256540 PMID:18392055 PMID:18504432 PMID:18611285 More...
G APOA1 apolipoprotein A1 treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G APOC3 apolipoprotein C3 treatment ISO RGD PMID:26996551 RGD:11561502 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26253517 NCBI chr 5:81,357,431...81,360,335
Ensembl chr 5:81,358,969...81,359,673 		JBrowse link
G ATM ATM serine/threonine kinase susceptibility ISO DNA:SNP:intron:(rs227060) (human) RGD PMID:28642860 RGD:150383339 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,657...36,759,552 		JBrowse link
G ATRX ATRX chromatin remodeler disease_progression ISO RGD PMID:29748005 PMID:31374064 RGD:127285382 RGD:127285383 NCBI chr  X:61,584,028...61,872,341
Ensembl chr  X:61,584,848...61,872,287 		JBrowse link
G AVP vasopressin ISO CTD Direct Evidence: marker/mechanism CTD PMID:2832203 NCBI chr17:32,581,234...32,583,145
Ensembl chr17:32,581,234...32,583,185 		JBrowse link
G AXIN2 axin 2 disease_progression ISO DNA:SNP::1386 C>T(human) RGD PMID:30346805 RGD:151356655 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,298...12,343,200 		JBrowse link
G B2M beta-2-microglobulin ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:26619011 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G BCL2 BCL2 apoptosis regulator susceptibility ISO DNA:SNP: :rs2279115(human) RGD PMID:26311051 RGD:13673911 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BCLAF1 BCL2 associated transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 1:27,872,167...27,902,980
Ensembl chr 1:27,872,183...27,902,974 		JBrowse link
G CCND1 cyclin D1 disease_progression ISO DNA:snp:exon:c.870G>A (human) RGD PMID:29739297 RGD:13673912 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B ISO protein:increased expression:lung RGD PMID:9500468 RGD:13673920 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
G CDYL chromodomain Y like ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 7:2,845,903...2,967,537
Ensembl chr 7:2,846,090...2,966,240 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit susceptibility ISO mRNA:increased expression:lung
DNA:SNP:cds:rs8040868(human)		 RGD PMID:20124469 PMID:22280835 RGD:150527851 RGD:151347453 NCBI chr 7:47,361,710...47,382,743
Ensembl chr 7:47,361,899...47,384,303 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 7:47,382,860...47,425,871
Ensembl chr 7:47,383,792...47,425,841 		JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit susceptibility ISO DNA:SNPs:multiples: RGD PMID:22280835 RGD:151347453 NCBI chr 8:31,430,933...31,456,385
Ensembl chr 8:31,443,043...31,456,384 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit ISO mRNA:increased expression:lung RGD PMID:20124469 RGD:150527851 NCBI chr 7:47,338,819...47,359,064 JBrowse link
G CKB creatine kinase B ISO CTD Direct Evidence: marker/mechanism CTD PMID:2828370
G CNTNAP2 contactin associated protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 9:109,740,510...111,781,144 JBrowse link
G COL22A1 collagen type XXII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:4,069,045...4,313,198
Ensembl chr 4:4,069,076...4,313,195 		JBrowse link
G COL4A2 collagen type IV alpha 2 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr11:76,996,885...77,161,617
Ensembl chr11:76,997,516...77,161,614 		JBrowse link
G CREBBP CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 3:38,388,366...38,530,243
Ensembl chr 3:38,388,547...38,530,224 		JBrowse link
G CSF1R colony stimulating factor 1 receptor exacerbates ISO protein:increased expression:lung (human) RGD PMID:1390197 RGD:150524305 NCBI chr 2:151,102,138...151,130,311
Ensembl chr 2:151,102,147...151,147,633 		JBrowse link
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:9093707 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 susceptibility ISO DNA:SNP:CDS: (rs6068816) (human) RGD PMID:31264381 RGD:151665340 NCBI chr17:55,110,546...55,130,328
Ensembl chr17:55,110,590...55,130,363 		JBrowse link
G DIP2C disco interacting protein 2 homolog C ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr10:68,770,149...69,141,876
Ensembl chr10:68,770,164...69,141,871 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 treatment ISO RGD PMID:33628824 RGD:155663482 NCBI chr 1:130,376,720...130,386,411
Ensembl chr 1:130,376,721...130,386,411 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta susceptibility ISO DNA:SNPs:promoter:-283T >C,-579G>T(human) RGD PMID:15528220 RGD:9589086 NCBI chr17:36,345,715...36,386,076
Ensembl chr17:36,345,816...36,386,072 		JBrowse link
G E2F1 E2F transcription factor 1 disease_progression
treatment		 ISO mRNA, protein:increased expression:lung RGD PMID:11313916 PMID:23792570 PMID:24755270 RGD:13464335 RGD:13464337 RGD:13464344 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,599...37,189,883 		JBrowse link
G EEF2 eukaryotic translation elongation factor 2 ISO protein:increased expression:lung (human) RGD PMID:24589652 RGD:153297816 NCBI chr 2:74,746,541...74,756,687
Ensembl chr 2:74,747,080...74,756,680 		JBrowse link
G EGFR epidermal growth factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20837450 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589 		JBrowse link
G ELAVL2 ELAV like RNA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 1:198,964,070...199,135,815
Ensembl chr 1:198,964,132...199,135,811 		JBrowse link
G EP300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G EPHA7 EPH receptor A7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 1:60,771,567...60,944,092
Ensembl chr 1:60,771,572...60,944,038 		JBrowse link
G FAT1 FAT atypical cadherin 1 ISO DNA:mutations:multiple (human) RGD PMID:31199602 RGD:150429733 NCBI chr17:8,466,099...8,580,715
Ensembl chr17:8,457,187...8,580,715 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,724 		JBrowse link
G FOXA1 forkhead box A1 disease_progression ISO RGD PMID:22383183 RGD:151665760 NCBI chr 7:62,471,233...62,479,638
Ensembl chr 7:62,471,249...62,479,220 		JBrowse link
G GRIK3 glutamate ionotropic receptor kainate type subunit 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 6:92,880,297...93,128,048
Ensembl chr 6:92,880,303...93,128,569 		JBrowse link
G GRM8 glutamate metabotropic receptor 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr18:20,945,049...21,756,952
Ensembl chr18:20,951,003...21,758,568 		JBrowse link
G GRP gastrin releasing peptide disease_progression ISO protein:increased expression:serum (human) RGD PMID:30146822 RGD:401700396 NCBI chr 1:161,708,815...161,721,986
Ensembl chr 1:161,708,812...161,721,782 		JBrowse link
G ID2 inhibitor of DNA binding 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G INSM1 INSM transcriptional repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23582323 NCBI chr17:28,379,529...28,382,554
Ensembl chr17:28,379,880...28,381,427 		JBrowse link
G ITGB1 integrin subunit beta 1 disease_progression
treatment		 ISO RGD PMID:12168902 PMID:21063403 RGD:13792831 RGD:13792832 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326 		JBrowse link
G KDM6A lysine demethylase 6A ISO DNA:mutations:multiple: (human) RGD PMID:31199602 RGD:150429733 NCBI chr  X:39,953,764...40,154,197
Ensembl chr  X:39,953,814...40,154,029 		JBrowse link
G KHSRP KH-type splicing regulatory protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 2:72,656,951...72,668,854
Ensembl chr 2:72,656,752...72,668,964 		JBrowse link
G KIF21A kinesin family member 21A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:70,888,999...71,029,832
Ensembl chr 5:70,889,000...71,029,809 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15499612 NCBI chr 8:41,402,334...41,492,306
Ensembl chr 8:41,402,043...41,493,734 		JBrowse link
G KMT2A lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 9:45,743,566...45,828,559
Ensembl chr 9:45,743,397...45,824,884 		JBrowse link
G KMT2D lysine methyltransferase 2D disease_progression ISO DNA:missense mutations, insertion/deletion:plasma RGD PMID:27873319 PMID:28007623 PMID:29627316 PMID:29748005 RGD:127285383 RGD:150523766 RGD:150523767 RGD:150523768 NCBI chr 5:15,049,827...15,091,622 JBrowse link
G LAMA3 laminin subunit alpha 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr 6:108,548,818...108,805,700
Ensembl chr 6:108,548,715...108,805,690 		JBrowse link
G LAMB3 laminin subunit beta 3 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr 9:133,298,009...133,351,162
Ensembl chr 9:133,311,834...133,351,197 		JBrowse link
G LAMC2 laminin subunit gamma 2 ISO DNA:hyper-methylation:promoter: RGD PMID:12855645 RGD:13793369 NCBI chr 9:124,427,545...124,499,672
Ensembl chr 9:124,435,807...124,495,351 		JBrowse link
G LYRM9 LYR motif containing 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr12:44,271,407...44,289,687
Ensembl chr12:44,271,524...44,289,612 		JBrowse link
G MAX MYC associated factor X ISO DNA:loss of heterozygosity:lung RGD PMID:24362264 RGD:13793386 NCBI chr 7:89,142,966...89,168,265
Ensembl chr 7:89,142,969...89,168,201 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase severity ISO protein:missense mutation:cds:p.A222V (human) RGD PMID:17533396 RGD:4891158 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G MTOR mechanistic target of rapamycin kinase disease_progression ISO DNA:SNP: :rs2536(human) RGD PMID:28280736 RGD:13825123 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor disease_progression ISO RGD PMID:28089889 RGD:13793389 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G MYCL MYCL proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: therapeutic CTD PMID:22941189 NCBI chr 6:95,696,086...95,702,627
Ensembl chr 6:95,696,094...95,702,648 		JBrowse link
G NDRG1 N-myc downstream regulated 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15341671 NCBI chr 4:8,014,445...8,069,335
Ensembl chr 4:8,014,446...8,069,335 		JBrowse link
G NOTCH1 notch receptor 1 treatment ISO RGD PMID:33628824 RGD:155663482
G PBRM1 polybromo 1 disease_progression ISO RGD PMID:29748005 RGD:127285383 NCBI chr13:34,689,718...34,821,117
Ensembl chr13:34,689,726...34,820,952 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:15016963 PMID:15254419 PMID:15520168 PMID:15608678 PMID:15647370 More... NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 disease_progression ISO DNA:SNPs: :rs3756668,rs12755(human) RGD PMID:28280736 RGD:13825123 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PLSCR4 phospholipid scramblase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr13:86,542,279...86,573,665
Ensembl chr13:86,542,283...86,573,629 		JBrowse link
G PTEN phosphatase and tensin homolog ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:1945792 PMID:9467011 PMID:9915974 PMID:10866302 PMID:11051241 More... NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTK2 protein tyrosine kinase 2 disease_progression ISO DNA:CNV:: RGD PMID:20802517 PMID:21800286 RGD:13825133 RGD:13825141 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G RAD52 RAD52 homolog, DNA repair protein treatment
susceptibility		 ISO DNA:SNP: (rs10774474)(human)
DNA:SNP:3'utr: (rs7963551) (human)		 RGD PMID:26629180 PMID:27531263 RGD:151660337 RGD:151660339 NCBI chr 5:68,140,846...68,223,587
Ensembl chr 5:68,143,646...68,169,670 		JBrowse link
G RARB retinoic acid receptor beta ISO DNA:methylation: : RGD PMID:29851970 RGD:13825142 NCBI chr13:12,336,387...12,507,688
Ensembl chr13:12,336,972...12,507,680 		JBrowse link
G RASSF8 Ras association domain family member 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 5:47,729,747...47,847,470
Ensembl chr 5:47,729,751...47,847,452 		JBrowse link
G RB1 RB transcriptional corepressor 1 ISO ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:1352883 PMID:2594029 PMID:7881418 PMID:9632788 PMID:9671401 More... NCBI chr11:19,186,754...19,317,642
Ensembl chr11:19,186,761...19,317,690 		JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 severity ISO associated with Neoplasm Metastasis; protein:increased expression:lung, lymph node (human)
DNA:CNV, amplification:exon (human)		 RGD PMID:27863413 PMID:31454632 RGD:152995447 RGD:152995517 NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,939...24,311,132 		JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:32,999,615...33,613,413
Ensembl chr 4:32,999,618...33,614,366 		JBrowse link
G RUNX1T1 RUNX1 partner transcriptional co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr 4:44,600,292...44,745,954
Ensembl chr 4:44,599,760...44,743,418 		JBrowse link
G SATB2 SATB homeobox 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr15:102,962,635...103,172,224
Ensembl chr15:102,964,417...103,158,232 		JBrowse link
G SKP2 S-phase kinase associated protein 2 ISO mRNA:increased expression:lung: RGD PMID:12107105 RGD:13825152 NCBI chr16:21,463,270...21,500,925
Ensembl chr16:21,463,012...21,509,310 		JBrowse link
G SLIT2 slit guidance ligand 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941188 NCBI chr 8:14,758,426...15,149,515
Ensembl chr 8:14,758,335...15,148,133 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26343384 NCBI chr 2:69,717,175...69,810,301
Ensembl chr 2:69,662,238...69,810,295 		JBrowse link
G SOX2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435 		JBrowse link
G TMEM132D transmembrane protein 132D ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr14:25,144,440...25,919,018
Ensembl chr14:25,144,430...25,913,052 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar PMID:1565143 PMID:1565144 PMID:1569604 PMID:1631137 PMID:1631151 More... NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G TP73 tumor protein p73 ISO DNA:mutations:multiple: (human) RGD PMID:26168399 RGD:151347582 NCBI chr 6:65,169,770...65,228,997
Ensembl chr 6:65,182,456...65,228,990 		JBrowse link
G TTR transthyretin ISO protein:increased expression:lung (human) RGD PMID:26943652 RGD:151665207 NCBI chr 6:115,496,338...115,503,974
Ensembl chr 6:115,496,326...115,503,977 		JBrowse link
G UBXN11 UBX domain protein 11 ISO ClinVar Annotator: match by term: Small cell lung cancer | ClinVar Annotator: match by term: Small cell lung carcinoma ClinVar NCBI chr 6:83,688,709...83,714,516
Ensembl chr 6:83,686,391...83,714,439 		JBrowse link
G XPO5 exportin 5 severity ISO DNA:snp, haplotype:3' utr:c.*659A>C (rs11077) (human) RGD PMID:24648983 RGD:11041738 NCBI chr 7:38,530,704...38,569,558
Ensembl chr 7:38,531,919...38,569,582 		JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22941189 NCBI chr15:109,563,445...109,593,858
Ensembl chr15:109,578,473...109,589,813 		JBrowse link
prostate small cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRCA2 BRCA2 DNA repair associated ISO ClinVar Annotator: match by term: Metastatic Prostate Small Cell Carcinoma ClinVar PMID:10660329 PMID:11597388 PMID:11802209 PMID:15024741 PMID:15689453 More... NCBI chr11:8,805,950...8,858,128
Ensembl chr11:8,805,913...8,857,793 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15394
    disease of cellular proliferation 7397
      cancer 5470
        cell type cancer 3678
          carcinoma 3132
            small cell carcinoma 102
              Bartholin's gland small cell carcinoma 0
              Desmoplastic Cerebral Astrocytoma of Infancy 0
              ampulla of Vater small cell carcinoma 0
              bladder small cell carcinoma 0
              colon small cell carcinoma 0
              endometrial small cell carcinoma 0
              esophagus small cell carcinoma 1
              gallbladder small cell carcinoma 0
              gastric small cell carcinoma 0
              laryngeal small cell carcinoma 0
              lung small cell carcinoma + 88
              prostate small cell carcinoma 1
              thymus small cell carcinoma 0
              ureter small cell carcinoma 0
paths to the root