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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:blood tissue inhibitor of metalloproteinase-1 level
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Accession:CMO:0003049 term browser browse the term
Definition:Measurement of the amount of tissue inhibitor of metalloproteinase 1 (TIMP-1)in a specific sample of blood. TIMP-1 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.


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  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood protein measurement 188
          blood tissue inhibitor of metalloproteinase-1 level 0
            serum tissue inhibitor of metalloproteinase 1 level 0
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