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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:serum autoantibody level
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Accession:CMO:0002109 term browser browse the term
Definition:Measurement of the amount of one or more autoantibodies in a specified sample of serum. An antibody is an immunoglobulin molecule possessing a specific amino acid sequence that binds to a specific antigen, a substance introduced into an organism which initiates an immune response including the production of the very antibodies which bind to it in an effort to destroy it. An autoantibody is an antibody that attacks the cells, tissues, native proteins, or other endogenous molecules of the organism in which it was formed.
Synonyms:exact_synonym: serum anti-self antibody level
 narrow_synonym: rheumatoid factor measurement
 xref: EFO:0005767


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serum autoantibody level term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1116951_H rheumatoid factor seropositivity measurement, rheumatoid factor measurement QTL GWAS1116951 (human) IAGP rs1502644 1.0E-8 GWAS_CATALOG PMID:26815016 NCBI chr 5:3,670,892...3,670,893 JBrowse link
Q GWAS1669978_H rheumatoid factor measurement QTL GWAS1669978 (human) IAGP rs34434863 5.0E-13 GWAS_CATALOG PMID:39024449 NCBI chr 6:32,591,896...32,591,897 JBrowse link
Q GWAS1669979_H rheumatoid factor measurement QTL GWAS1669979 (human) IAGP rs34434863 2.0E-12 GWAS_CATALOG PMID:39024449 NCBI chr 6:32,591,896...32,591,897 JBrowse link
Q GWAS1670491_H rheumatoid factor measurement QTL GWAS1670491 (human) IAGP rs34434863 6.0E-13 GWAS_CATALOG PMID:39024449 NCBI chr 6:32,591,896...32,591,897 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 213573
    immune system measurement 23526
      immunoglobulin measurement 259
        blood immunoglobulin measurement 237
          serum immunoglobulin measurement 125
            serum antibody level 125
              serum autoantibody level 4
                serum anti-rat type 2 collagen autoantibody level + 0
                serum autoantibody titer + 0
                serum immunoglobulin G-type rheumatoid factor level + 0
                serum immunoglobulin M-type rheumatoid factor level + 0
Path 2
Term Annotations click to browse term
  clinical measurement 213573
    blood measurement 138936
      blood chemistry measurement 88488
        blood protein measurement 60344
          blood globulin measurement 290
            blood immunoglobulin measurement 237
              blood antibody level 215
                serum antibody level 125
                  serum autoantibody level 4
                    serum anti-rat type 2 collagen autoantibody level + 0
                    serum autoantibody titer + 0
                    serum immunoglobulin G-type rheumatoid factor level + 0
                    serum immunoglobulin M-type rheumatoid factor level + 0
paths to the root