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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:spinal cord MHC class II protein measurement
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Accession:CMO:0001982 term browser browse the term
Definition:Any quantification of one or more of the major histocompatibility complex (MHC) class II molecules of the spinal cord. MHC class II is a group of proteins that are involved in antigen presentation and self recognition, and have been implicated in allograft rejection and autoimmunity.



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MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Neuinf2 Neuroinflammation QTL 2 IDA RGD PMID:14586010 RGD:1358788 NCBI chr10:6,154,377...6,357,896 JBrowse link
Q Neuinf3 Neuroinflammation QTL 3 IDA RGD PMID:14586010 RGD:1358788 NCBI chr10:3,406,320...5,387,112 JBrowse link
spinal cord RT1-B protein level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Neuinf4 Neuroinflammation QTL 4 IDA RGD PMID:19525015 RGD:2311085 NCBI chr 1:1...28,736,750 JBrowse link
Q Neuinf6 Neuroinflammation QTL 6 IDA RGD PMID:19525015 RGD:2311085 NCBI chr 7:1...27,829,089 JBrowse link
Q Neuinf7 Neuroinflammation QTL 7 IDA RGD PMID:19525015 RGD:2311085 NCBI chr10:72,224,939...107,211,142 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    tissue composition measurement 26
      tissue molecular composition measurement 26
        spinal cord molecular composition measurement 11
          spinal cord protein/peptide composition measurement 6
            spinal cord MHC class II protein measurement 5
              MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio 2
              spinal cord RT1-B protein level 3
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    nervous system measurement 63
      central nervous system measurement 29
        spinal cord measurement 11
          spinal cord morphological measurement 11
            spinal cord molecular composition measurement 11
              spinal cord protein/peptide composition measurement 6
                spinal cord MHC class II protein measurement 5
                  MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio 2
                  spinal cord RT1-B protein level 3
paths to the root