The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Any measurement in which the number of individuals in a study population that display colonic aganglionosis at a point in time or develop colonic aganglionosis within a determined period of time are compared to the total number of individuals in the study population. Often expressed as a percentage but could be expressed as a ratio. Colonic aganglionosis is the absence of parasympathetic ganglion cells in any or all of the myenteric plexus, a network of autonomic nerve fibers within the tunica muscularis of the wall of the alimentary canal in general and of the colon in particular. The colon is the segment of the large intestine between the cecum and the rectum.