CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: venlafaxine
Accession: CHEBI:9943
browse the term
Definition: A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.
Synonyms: exact_synonym: 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol
related_synonym: Elafax; Formula=C17H27NO2; InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3; InChIKey=PNVNVHUZROJLTJ-UHFFFAOYSA-N; SMILES=COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1; venlafaxina; venlafaxinum
xref: Beilstein:4234848; CAS:93413-69-5; DrugBank:DB00285; Drug_Central:2813; HMDB:HMDB0005016; KEGG:C07187; KEGG:D08670; LINCS:LSM-1616
xref_mesh: MESH:C047426
xref: PMID:11098420; PMID:12409680; PMID:18321472; Reaxys:4234848; Wikipedia:Venlafaxine
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression increases export
ISO
Venlafaxine Hydrochloride results in increased expression of ABCB1 mRNA ABCB1 protein results in increased export of Venlafaxine Hydrochloride
CTD
PMID:14550684 PMID:17191263
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc1
ATP binding cassette subfamily C member 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of ABCC1 mRNA
CTD
PMID:17191263
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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Ace
angiotensin I converting enzyme
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ACE mRNA
CTD
PMID:25423262
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Acp5
acid phosphatase 5, tartrate resistant
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of ACP5 mRNA
CTD
PMID:16341940
NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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Acta2
actin alpha 2, smooth muscle
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of ACTA2 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of ACTA2 protein]
CTD
PMID:35104487
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Acvr1c
activin A receptor type 1C
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ACVR1C mRNA
CTD
PMID:25423262
NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
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Adam10
ADAM metallopeptidase domain 10
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ADAM10 mRNA
CTD
PMID:25423262
NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889
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Adgrl1
adhesion G protein-coupled receptor L1
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of ADGRL1 mRNA
CTD
PMID:25423262
NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139
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Ago2
argonaute RISC catalytic component 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of AGO2 mRNA
CTD
PMID:25423262
NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
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Ahr
aryl hydrocarbon receptor
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of AHR mRNA
CTD
PMID:25423262
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Akap5
A-kinase anchoring protein 5
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of AKAP5 mRNA
CTD
PMID:25423262
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Akt1
AKT serine/threonine kinase 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of AKT1 protein
CTD
PMID:18511088
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alb
albumin
multiple interactions
EXP
Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in decreased expression of ALB protein]
CTD
PMID:29852128
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Alcam
activated leukocyte cell adhesion molecule
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ALCAM mRNA
CTD
PMID:25423262
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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Ankrd55
ankyrin repeat domain 55
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of ANKRD55 mRNA
CTD
PMID:16341940
NCBI chr 2:43,883,877...43,983,820
Ensembl chr 2:43,883,857...43,983,680
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Ap2b1
adaptor related protein complex 2 subunit beta 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of AP2B1 mRNA
CTD
PMID:25423262
NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
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Ar
androgen receptor
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of AR protein
CTD
PMID:36063371
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Arc
activity-regulated cytoskeleton-associated protein
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ARC mRNA; Venlafaxine Hydrochloride results in increased expression of ARC protein
CTD
PMID:14580947 PMID:15087240 PMID:15838995
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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Arf3
ADP-ribosylation factor 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of ARF3 mRNA
CTD
PMID:25423262
NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002
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Arhgap10
Rho GTPase activating protein 10
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of ARHGAP10 mRNA
CTD
PMID:16341940
NCBI chr19:30,448,572...30,710,315
Ensembl chr19:30,448,637...30,710,313
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Arhgef9
Cdc42 guanine nucleotide exchange factor 9
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ARHGEF9 mRNA
CTD
PMID:25423262
NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513
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Ascl1
achaete-scute family bHLH transcription factor 1
decreases expression increases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of ASCL1 mRNA Venlafaxine Hydrochloride results in increased expression of ASCL1 mRNA
CTD
PMID:25423262
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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Atp2b3
ATPase plasma membrane Ca2+ transporting 3
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ATP2B3 mRNA
CTD
PMID:25423262
NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775
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Atrx
ATRX, chromatin remodeler
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ATRX mRNA
CTD
PMID:25423262
NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of BAX protein]]; Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of BAX protein]
CTD
PMID:29852128 PMID:35104487
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions
EXP
Venlafaxine Hydrochloride results in decreased expression of BCL2 mRNA Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]
CTD
PMID:25423262 PMID:29852128 PMID:35104487
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of BDNF mRNA
CTD
PMID:17950272
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Becn1
beclin 1
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of BECN1 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of BECN1 protein]
CTD
PMID:35104487
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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Brinp3
BMP/retinoic acid inducible neural specific 3
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of BRINP3 mRNA
CTD
PMID:16341940
NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770
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Cacnb4
calcium voltage-gated channel auxiliary subunit beta 4
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CACNB4 mRNA
CTD
PMID:25423262
NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944
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Calm3
calmodulin 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of CALM3 mRNA
CTD
PMID:25423262
NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CAMK2A mRNA
CTD
PMID:25423262
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Camk2b
calcium/calmodulin-dependent protein kinase II beta
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of CAMK2B mRNA
CTD
PMID:25423262
NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
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Camk2g
calcium/calmodulin-dependent protein kinase II gamma
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of CAMK2G mRNA
CTD
PMID:25423262
NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
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Casp3
caspase 3
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of CASP3 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of CASP3 protein]
CTD
PMID:29852128 PMID:35104487
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
multiple interactions
EXP
Nitric Oxide promotes the reaction [Venlafaxine Hydrochloride inhibits the reaction [3-nitropropionic acid results in decreased activity of CAT protein]]; Venlafaxine Hydrochloride inhibits the reaction [3-nitropropionic acid results in decreased activity of CAT protein]; Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
CTD
PMID:20305041 PMID:29852128
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cd47
Cd47 molecule
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of CD47 mRNA
CTD
PMID:25423262
NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
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Cdh22
cadherin 22
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of CDH22 mRNA
CTD
PMID:25423262
NCBI chr 3:153,845,563...153,970,630
Ensembl chr 3:153,845,787...153,970,588
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Celf2
CUGBP, Elav-like family member 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CELF2 mRNA
CTD
PMID:25423262
NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
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Clns1a
chloride nucleotide-sensitive channel 1A
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of CLNS1A mRNA
CTD
PMID:25423262
NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
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Clstn2
calsyntenin 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of CLSTN2 mRNA
CTD
PMID:25423262
NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731
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Cnbp
CCHC-type zinc finger, nucleic acid binding protein
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CNBP mRNA
CTD
PMID:25423262
NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
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Cnr1
cannabinoid receptor 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CNR1 mRNA
CTD
PMID:25423262
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Cntn2
contactin 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CNTN2 mRNA
CTD
PMID:25423262
NCBI chr13:43,942,868...43,975,973
Ensembl chr13:43,947,265...43,975,887
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Cox17
cytochrome c oxidase copper chaperone COX17
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of COX17 mRNA
CTD
PMID:25423262
NCBI chr11:62,400,733...62,406,507
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Cpd
carboxypeptidase D
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CPD mRNA
CTD
PMID:25423262
NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
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Ctnnb1
catenin beta 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CTNNB1 protein
CTD
PMID:18511088
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Cxxc4
CXXC finger protein 4
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of CXXC4 mRNA
CTD
PMID:25423262
NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
multiple interactions decreases activity
ISO
Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Pregnenolone] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased hydroxylation of Progesterone] which results in increased chemical synthesis of 17-alpha-Hydroxyprogesterone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone] which results in increased chemical synthesis of Dehydroepiandrosterone]; Venlafaxine Hydrochloride inhibits the reaction [[CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] which results in increased chemical synthesis of Androstenedione]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Pregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased hydroxylation of Progesterone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxypregnenolone]; Venlafaxine Hydrochloride inhibits the reaction [CYP17A1 protein results in increased metabolism of 17-alpha-Hydroxyprogesterone] Venlafaxine Hydrochloride results in decreased activity of CYP17A1 protein
CTD
PMID:29100959
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
affects methylation decreases methylation
ISO
CYP2C19 gene polymorphism affects the methylation of Venlafaxine Hydrochloride CYP2C19 protein results in decreased methylation of Venlafaxine Hydrochloride
CTD
PMID:10877013
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects metabolic processing decreases activity increases metabolic processing decreases methylation affects response to substance affects methylation
ISO
CYP2D6 gene mutant form affects the metabolism of Venlafaxine Hydrochloride; CYP2D6 gene polymorphism affects the metabolism of Venlafaxine Hydrochloride Venlafaxine Hydrochloride results in decreased activity of CYP2D6 protein CYP2D6 protein results in increased metabolism of Venlafaxine Hydrochloride CYP2D6 protein results in decreased methylation of Venlafaxine Hydrochloride CYP2D6 protein affects the susceptibility to Venlafaxine Hydrochloride CYP2D6 gene polymorphism affects the methylation of Venlafaxine Hydrochloride
CTD
PMID:10774634 PMID:10877013 PMID:10933885 PMID:15632378 PMID:16044105 PMID:16958828 PMID:17803873 PMID:18214456 More...
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Dab2
DAB adaptor protein 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of DAB2 mRNA
CTD
PMID:25423262
NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
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Ddah1
dimethylarginine dimethylaminohydrolase 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of DDAH1 mRNA
CTD
PMID:25423262
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
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Dmac1
distal membrane arm assembly component 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of DMAC1 mRNA
CTD
PMID:16341940
NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757
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Dnmt3a
DNA methyltransferase 3 alpha
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of DNMT3A mRNA
CTD
PMID:25423262
NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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Dpp4
dipeptidylpeptidase 4
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of DPP4 mRNA
CTD
PMID:25423262
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Ednrb
endothelin receptor type B
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of EDNRB mRNA
CTD
PMID:25423262
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of ENPP1 mRNA
CTD
PMID:25423262
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
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Epha5
EPH receptor A5
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of EPHA5 mRNA
CTD
PMID:25423262
NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317
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Fmnl1
formin-like 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of FMNL1 mRNA
CTD
PMID:16341940
NCBI chr10:88,115,876...88,143,342
Ensembl chr10:88,116,009...88,143,357
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Gabrb1
gamma-aminobutyric acid type A receptor subunit beta1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GABRB1 mRNA
CTD
PMID:25423262
NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
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Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GABRB2 mRNA
CTD
PMID:25423262
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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Gad2
glutamate decarboxylase 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of GAD2 mRNA
CTD
PMID:25423262
NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
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Gas2
growth arrest-specific 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of GAS2 mRNA
CTD
PMID:25423262
NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619
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Gas6
growth arrest specific 6
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GAS6 mRNA
CTD
PMID:25423262
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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Gda
guanine deaminase
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GDA mRNA
CTD
PMID:25423262
NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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Gfap
glial fibrillary acidic protein
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GFAP mRNA
CTD
PMID:25423262
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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Glp1r
glucagon-like peptide 1 receptor
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of GLP1R mRNA
CTD
PMID:25423262
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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Gnao1
G protein subunit alpha o1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GNAO1 mRNA
CTD
PMID:25423262
NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493
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Gnaq
G protein subunit alpha q
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of GNAQ mRNA
CTD
PMID:25423262
NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
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Gria1
glutamate ionotropic receptor AMPA type subunit 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of GRIA1 mRNA
CTD
PMID:25423262
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
G
Gria3
glutamate ionotropic receptor AMPA type subunit 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of GRIA3 mRNA
CTD
PMID:25423262
NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of GRIN2A mRNA
CTD
PMID:25423262
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of GRIN2B mRNA
CTD
PMID:25423262
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Hcn1
hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of HCN1 mRNA
CTD
PMID:25423262
NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
G
Hdac6
histone deacetylase 6
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of HDAC6 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of HDAC6 protein]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in increased expression of HDAC6 protein]
CTD
PMID:35104487
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
G
Hook2
hook microtubule-tethering protein 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of HOOK2 mRNA
CTD
PMID:25423262
NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181
G
Il1rapl1
interleukin 1 receptor accessory protein-like 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of IL1RAPL1 mRNA
CTD
PMID:25423262
NCBI chr X:51,371,969...52,876,726
Ensembl chr X:51,378,215...52,876,772
G
Kcnc2
potassium voltage-gated channel subfamily C member 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of KCNC2 mRNA
CTD
PMID:25423262
NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
G
Kcnh2
potassium voltage-gated channel subfamily H member 2
decreases activity
ISO
Venlafaxine Hydrochloride results in decreased activity of KCNH2 protein
CTD
PMID:21158687
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
G
Kcnj3
potassium inwardly-rectifying channel, subfamily J, member 3
multiple interactions
ISO
Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
CTD
PMID:22164246
NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124
G
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
multiple interactions
ISO
Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]
CTD
PMID:22164246
NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
G
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
multiple interactions
ISO
Venlafaxine Hydrochloride affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]
CTD
PMID:22164246
NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758
G
Kcnk1
potassium two pore domain channel subfamily K member 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of KCNK1 mRNA
CTD
PMID:25423262
NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
G
Kif1b
kinesin family member 1B
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of KIF1B mRNA
CTD
PMID:25423262
NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
G
Kif2b
kinesin family member 2B
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of KIF2B mRNA
CTD
PMID:25423262
NCBI chr10:76,394,160...76,396,379
G
Kif5a
kinesin family member 5A
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of KIF5A mRNA
CTD
PMID:25423262
NCBI chr 7:63,051,894...63,089,024
Ensembl chr 7:63,049,424...63,092,858
G
Klf6
KLF transcription factor 6
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of KLF6 mRNA
CTD
PMID:25423262
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
G
Klhl24
kelch-like family member 24
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of KLHL24 mRNA
CTD
PMID:25423262
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
G
Klk10
kallikrein related-peptidase 10
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of KLK10 mRNA
CTD
PMID:16341940
NCBI chr 1:94,234,536...94,239,369
Ensembl chr 1:94,235,096...94,239,376
G
Large1
LARGE xylosyl- and glucuronyltransferase 1
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of LARGE1 mRNA
CTD
PMID:16341940
NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
G
Lipg
lipase G, endothelial type
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of LIPG mRNA
CTD
PMID:16341940
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
G
Lman1
lectin, mannose-binding, 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of LMAN1 mRNA
CTD
PMID:25423262
NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851
G
Lmo7
LIM domain 7
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of LMO7 mRNA
CTD
PMID:16341940
NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783
G
Lpl
lipoprotein lipase
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of LPL mRNA
CTD
PMID:25423262
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
G
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of MAGI2 mRNA
CTD
PMID:25423262
NCBI chr 4:14,386,389...15,870,036
Ensembl chr 4:14,386,399...15,870,240
G
Map1lc3b
microtubule-associated protein 1 light chain 3 beta
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased lipidation of MAP1LC3B protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased lipidation of MAP1LC3B protein]
CTD
PMID:35104487
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
G
Map2
microtubule-associated protein 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of MAP2 mRNA
CTD
PMID:25423262
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
G
Mapk1
mitogen activated protein kinase 1
increases phosphorylation
EXP
Venlafaxine Hydrochloride results in increased phosphorylation of MAPK1 protein
CTD
PMID:18511088
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation
EXP
Venlafaxine Hydrochloride results in increased phosphorylation of MAPK3 protein
CTD
PMID:18511088
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of MFNG mRNA
CTD
PMID:25423262
NCBI chr 7:110,310,810...110,328,653
Ensembl chr 7:110,310,812...110,328,653
G
Mmp9
matrix metallopeptidase 9
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of MMP9 mRNA
CTD
PMID:25423262
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
G
Mpp2
MAGUK p55 scaffold protein 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of MPP2 mRNA
CTD
PMID:25423262
NCBI chr10:87,011,434...87,043,883
Ensembl chr10:87,011,434...87,043,896
G
Mvp
major vault protein
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of MVP mRNA
CTD
PMID:16341940
NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380
G
Myo5a
myosin VA
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of MYO5A mRNA
CTD
PMID:25423262
NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
G
Nasp
nuclear autoantigenic sperm protein
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of NASP mRNA
CTD
PMID:16341940
NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928
G
Negr1
neuronal growth regulator 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NEGR1 mRNA
CTD
PMID:25423262
NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730
G
Nell2
neural EGFL like 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of NELL2 mRNA
CTD
PMID:25423262
NCBI chr 7:126,343,089...126,662,903
Ensembl chr 7:126,198,851...126,733,503
G
Neurod1
neuronal differentiation 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of NEUROD1 mRNA
CTD
PMID:25423262
NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
G
Nfix
nuclear factor I X
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of NFIX mRNA
CTD
PMID:25423262
NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
G
Nptxr
neuronal pentraxin receptor
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NPTXR mRNA
CTD
PMID:25423262
NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
G
Nr3c1
nuclear receptor subfamily 3, group C, member 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NR3C1 mRNA
CTD
PMID:11406320
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
G
Nr3c2
nuclear receptor subfamily 3, group C, member 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NR3C2 mRNA
CTD
PMID:11406320
NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
G
Nsun2
NOP2/Sun RNA methyltransferase 2
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of NSUN2 mRNA
CTD
PMID:16341940
NCBI chr 1:33,662,139...33,685,887
Ensembl chr 1:33,662,139...33,685,862
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NTRK2 mRNA
CTD
PMID:25423262
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
G
Ntrk3
neurotrophic receptor tyrosine kinase 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of NTRK3 mRNA
CTD
PMID:25423262
NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
G
Pdap1
PDGFA associated protein 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PDAP1 mRNA
CTD
PMID:25423262
NCBI chr12:9,470,652...9,480,880
Ensembl chr12:9,470,574...9,535,374
G
Pde4b
phosphodiesterase 4B
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PDE4B mRNA
CTD
PMID:25423262
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
G
Pde4d
phosphodiesterase 4D
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PDE4D mRNA
CTD
PMID:25423262
NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
G
Pdia3
protein disulfide isomerase family A, member 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PDIA3 mRNA
CTD
PMID:25423262
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of PDPK1 mRNA
CTD
PMID:25423262
NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
G
Pex2
peroxisomal biogenesis factor 2
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of PEX2 mRNA
CTD
PMID:25423262
NCBI chr 2:96,050,380...96,072,928
Ensembl chr 2:96,045,958...96,073,404
G
Pgrmc1
progesterone receptor membrane component 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PGRMC1 mRNA
CTD
PMID:25423262
NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682
G
Pim3
Pim-3 proto-oncogene, serine/threonine kinase
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PIM3 mRNA
CTD
PMID:25423262
NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
G
Pou3f2
POU class 3 homeobox 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of POU3F2 mRNA
CTD
PMID:25423262
NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838
G
Ppp1ca
protein phosphatase 1 catalytic subunit alpha
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PPP1CA mRNA
CTD
PMID:25423262
NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
G
Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PPP1R3A mRNA
CTD
PMID:25423262
NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638
G
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PPP1R9B mRNA
CTD
PMID:25423262
NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
G
Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PPP3R1 mRNA
CTD
PMID:25423262
NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
G
Prap1
proline-rich acidic protein 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PRAP1 mRNA
CTD
PMID:25423262
NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872
G
Prdx1
peroxiredoxin 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of PRDX1 mRNA
CTD
PMID:25423262
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
G
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of PREX2 mRNA
CTD
PMID:16341940
NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068
G
Prkce
protein kinase C, epsilon
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PRKCE mRNA
CTD
PMID:25423262
NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
G
Prkg2
protein kinase cGMP-dependent 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PRKG2 mRNA
CTD
PMID:25423262
NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888
G
Prkn
parkin RBR E3 ubiquitin protein ligase
multiple interactions
EXP
Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]
CTD
PMID:35104487
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
G
Prl
prolactin
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of PRL protein
CTD
PMID:17606668
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
G
Pyy
peptide YY
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of PYY mRNA
CTD
PMID:25423262
NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
G
Rab14
RAB14, member RAS oncogene family
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of RAB14 mRNA
CTD
PMID:25423262
NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172
G
Rab4b
RAB4B, member RAS oncogene family
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of RAB4B mRNA
CTD
PMID:25423262
NCBI chr 1:82,461,396...82,472,784
Ensembl chr 1:82,461,396...82,472,763
G
Rcc1
regulator of chromosome condensation 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of RCC1 mRNA
CTD
PMID:16341940
NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
EXP
Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased expression of RELA protein]
CTD
PMID:29852128
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rims1
regulating synaptic membrane exocytosis 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of RIMS1 mRNA
CTD
PMID:25423262
NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631
G
Ring1
ring finger protein 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of RING1 mRNA
CTD
PMID:16341940
NCBI chr20:4,830,120...4,833,623
Ensembl chr20:4,830,053...4,833,620
G
Rph3a
rabphilin 3A
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of RPH3A mRNA
CTD
PMID:25423262
NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592
G
Sall1
spalt-like transcription factor 1
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of SALL1 mRNA
CTD
PMID:16341940
NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
G
Serpini1
serpin family I member 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SERPINI1 mRNA
CTD
PMID:16637596
NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
G
Sgtb
small glutamine rich tetratricopeptide repeat co-chaperone beta
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SGTB mRNA
CTD
PMID:25423262
NCBI chr 2:35,233,045...35,269,527
Ensembl chr 2:35,233,042...35,269,518
G
Shank2
SH3 and multiple ankyrin repeat domains 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SHANK2 mRNA
CTD
PMID:25423262
NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
G
Sipa1l1
signal-induced proliferation-associated 1 like 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SIPA1L1 mRNA
CTD
PMID:25423262
NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950
G
Slc26a3
solute carrier family 26 member 3
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SLC26A3 mRNA
CTD
PMID:25423262
NCBI chr 6:48,023,892...48,064,829
Ensembl chr 6:48,023,892...48,064,772
G
Slc2a4
solute carrier family 2 member 4
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of SLC2A4 mRNA
CTD
PMID:25423262
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
G
Slc4a4
solute carrier family 4 member 4
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SLC4A4 mRNA
CTD
PMID:25423262
NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
G
Slc5a1
solute carrier family 5 member 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SLC5A1 mRNA
CTD
PMID:25423262
NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
G
Slc6a4
solute carrier family 6 member 4
affects response to substance
ISO
SLC6A4 gene polymorphism affects the susceptibility to Venlafaxine Hydrochloride
CTD
PMID:17503984
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Slc6a6
solute carrier family 6 member 6
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SLC6A6 mRNA
CTD
PMID:25423262
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Sod1
superoxide dismutase 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SOD1 mRNA
CTD
PMID:10721683
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Spn
sialophorin
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SPN mRNA
CTD
PMID:25423262
NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
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Sqstm1
sequestosome 1
decreases expression multiple interactions
EXP
Venlafaxine Hydrochloride results in decreased expression of SQSTM1 mRNA Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]]; Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of SQSTM1 protein]
CTD
PMID:25423262 PMID:35104487
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Stau2
staufen double-stranded RNA binding protein 2
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of STAU2 mRNA
CTD
PMID:25423262
NCBI chr 5:2,840,741...3,084,935
Ensembl chr 5:2,840,765...3,084,929
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Stk39
serine threonine kinase 39
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of STK39 mRNA
CTD
PMID:25423262
NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
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Sv2b
synaptic vesicle glycoprotein 2b
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of SV2B mRNA
CTD
PMID:25423262
NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
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Syn2
synapsin II
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of SYN2 mRNA
CTD
PMID:25423262
NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
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Synj2
synaptojanin 2
affects expression
EXP
Venlafaxine Hydrochloride affects the expression of SYNJ2 mRNA
CTD
PMID:25423262
NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687
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Syp
synaptophysin
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of SYP mRNA
CTD
PMID:17950272
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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Syt4
synaptotagmin 4
increases expression
ISO
Venlafaxine Hydrochloride results in increased expression of SYT4 mRNA
CTD
PMID:16341940
NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332
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Tacr3
tachykinin receptor 3
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of TACR3 mRNA
CTD
PMID:25423262
NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
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Tcf12
transcription factor 12
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of TCF12 mRNA
CTD
PMID:16341940
NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201
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Tcf4
transcription factor 4
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of TCF4 mRNA
CTD
PMID:25423262
NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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Thbd
thrombomodulin
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of THBD mRNA
CTD
PMID:25423262
NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
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Tp53
tumor protein p53
multiple interactions
EXP
Venlafaxine Hydrochloride inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
CTD
PMID:29852128
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Trim13
tripartite motif-containing 13
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of TRIM13 mRNA
CTD
PMID:16341940
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
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Tshr
thyroid stimulating hormone receptor
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of TSHR mRNA
CTD
PMID:25423262
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
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Txn2
thioredoxin 2
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of TXN2 mRNA
CTD
PMID:25423262
NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
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Ube2q1
ubiquitin conjugating enzyme E2 Q1
decreases expression
ISO
Venlafaxine Hydrochloride results in decreased expression of UBE2Q1 mRNA
CTD
PMID:16341940
NCBI chr 2:175,198,793...175,209,152
Ensembl chr 2:175,198,873...175,207,942
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Ucp3
uncoupling protein 3
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of UCP3 mRNA
CTD
PMID:25423262
NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
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Unc13b
unc-13 homolog B
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of UNC13B mRNA
CTD
PMID:25423262
NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
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Vamp1
vesicle-associated membrane protein 1
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of VAMP1 mRNA
CTD
PMID:25423262
NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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Vcpip1
valosin containing protein interacting protein 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of VCPIP1 mRNA
CTD
PMID:25423262
NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
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Vdac1
voltage-dependent anion channel 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of VDAC1 mRNA
CTD
PMID:25423262
NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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Vegfb
vascular endothelial growth factor B
decreases expression
EXP
Venlafaxine Hydrochloride results in decreased expression of VEGFB mRNA
CTD
PMID:25423262
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Wdfy1
WD repeat and FYVE domain containing 1
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of WDFY1 mRNA
CTD
PMID:25423262
NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775
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Zfp24
zinc finger protein 24
increases expression
EXP
Venlafaxine Hydrochloride results in increased expression of ZFP24 mRNA
CTD
PMID:25423262
NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799
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