CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Valacyclovir hydrochloride
Accession: CHEBI:9919
browse the term
Definition: An organic molecular entity that has formula C13H20N6O4.HCl.
Synonyms: related_synonym: BW 256U87; Formula=C13H20N6O4.HCl; InChI=1S/C13H20N6O4.ClH/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20;/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20);1H/t8-;/m0./s1; InChIKey=ZCDDBUOENGJMLV-QRPNPIFTSA-N; SMILES=Cl.CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O; Valacyclovir
xref: CAS:124832-27-5; KEGG:C07184; KEGG:D00398
xref_mesh: MESH:D000077483
G
Bphl
biphenyl hydrolase like
increases hydrolysis
ISO
BPHL protein results in increased hydrolysis of Valacyclovir
CTD
PMID:15832508
NCBI chr17:31,006,283...31,042,631
Ensembl chr17:31,004,972...31,042,632
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
decreases activity
ISO
Valacyclovir results in decreased activity of CYP1A1 protein
CTD
PMID:33814510
NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases activity
ISO
Valacyclovir results in decreased activity of CYP1B1 protein
CTD
PMID:33814510
NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all