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G |
Ache |
acetylcholinesterase |
multiple interactions |
ISO |
Tubocurarine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Tubocurarine promotes the reaction [haloxon results in increased phosphorylation of ACHE protein]; Tubocurarine promotes the reaction [Paraoxon results in increased phosphorylation of ACHE protein] |
CTD |
PMID:10421444 |
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NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [[Nicotine results in increased metabolism of APP protein] which results in increased secretion of APP protein modified form]; Tubocurarine inhibits the reaction [Nicotine results in increased metabolism of APP protein] |
CTD |
PMID:29618714 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [PTMA protein results in decreased expression of BCL2] |
CTD |
PMID:16644063 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of BGLAP] |
CTD |
PMID:19436947 |
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NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
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G |
C7 |
complement C7 |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of C7 mRNA] Tubocurarine results in decreased expression of C7 mRNA |
CTD |
PMID:16949557 |
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NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
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G |
Cdk4 |
cyclin-dependent kinase 4 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] |
CTD |
PMID:15231866 |
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NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
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G |
Chrna1 |
cholinergic receptor nicotinic alpha 1 subunit |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [CHRNA1 protein binds to PLAU protein] |
CTD |
PMID:19690163 |
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NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724
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G |
Chrna2 |
cholinergic receptor nicotinic alpha 2 subunit |
multiple interactions |
EXP |
Tubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA2 protein]]; Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]] |
CTD |
PMID:7808438 |
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NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
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G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
multiple interactions |
ISO EXP |
Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] Tubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA3 protein]]; Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]]; Tubocurarine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] |
CTD |
PMID:7808438 PMID:9687574 PMID:16931985 |
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NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
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G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Ethinyl Estradiol promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]]; Tubocurarine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] Tubocurarine inhibits the reaction [Nicotine results in increased expression of CHRNA4 protein] |
CTD |
PMID:7756618 PMID:11711029 PMID:14645658 PMID:16931985 |
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NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
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G |
Chrna7 |
cholinergic receptor nicotinic alpha 7 subunit |
multiple interactions |
ISO |
Tubocurarine binds to and results in decreased activity of CHRNA7 protein; Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of CHRNA7 protein]; Tubocurarine inhibits the reaction [Bungarotoxins binds to CHRNA7 protein] |
CTD |
PMID:10082212 PMID:10216184 PMID:16931985 |
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NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
multiple interactions |
ISO EXP |
Tubocurarine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [epibatidine binds to [CHRNA4 protein binds to CHRNB2 protein]]; Tubocurarine inhibits the reaction [Ethinyl Estradiol promotes the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]]]; Tubocurarine results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein] Tubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA2 protein]]; Tubocurarine inhibits the reaction [Acetylcholine binds to and results in increased activity of [CHRNB2 protein binds to CHRNA3 protein]] Tubocurarine inhibits the reaction [Nicotine results in increased expression of CHRNB2 protein] |
CTD |
PMID:7756618 PMID:7808438 PMID:11711029 PMID:14645658 PMID:16931985 |
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NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
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G |
Chrnb4 |
cholinergic receptor nicotinic beta 4 subunit |
multiple interactions |
ISO EXP |
Tubocurarine inhibits the reaction [Acetylcholine results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]] Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA2 protein]]; Tubocurarine promotes the reaction [Acetylcholine binds to and results in increased activity of [CHRNB4 protein binds to CHRNA3 protein]]; Tubocurarine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein] |
CTD |
PMID:7808438 PMID:9687574 PMID:16931985 |
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NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
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G |
Cntn1 |
contactin 1 |
increases expression decreases expression multiple interactions |
ISO |
Tubocurarine results in increased expression of CNTN1 mRNA Tubocurarine results in decreased expression of CNTN1 mRNA Tubocurarine inhibits the reaction [Nicotine results in decreased expression of CNTN1 mRNA]; Tubocurarine inhibits the reaction [Nicotine results in increased expression of CNTN1 mRNA] |
CTD |
PMID:12588870 PMID:16949557 |
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NCBI chr 7:133,290,606...133,588,314
Ensembl chr 7:133,400,485...133,586,677
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased secretion of CSF2 protein] |
CTD |
PMID:9606035 |
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NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
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G |
Dhfr |
dihydrofolate reductase |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of DHFR mRNA] Tubocurarine results in decreased expression of DHFR mRNA |
CTD |
PMID:12588870 |
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NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
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G |
Eml4 |
EMAP like 4 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of EML4 mRNA] |
CTD |
PMID:12588870 |
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NCBI chr 6:6,618,370...6,674,550
Ensembl chr 6:6,619,076...6,674,554
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G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [PTMA protein results in increased expression of FAS] |
CTD |
PMID:16644063 |
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NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
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G |
Fez1 |
fasciculation and elongation protein zeta 1 |
multiple interactions decreases expression |
ISO |
Tubocurarine promotes the reaction [Nicotine results in decreased expression of FEZ1 mRNA] Tubocurarine results in decreased expression of FEZ1 mRNA |
CTD |
PMID:12588870 |
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NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of FOS] |
CTD |
PMID:11425648 |
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NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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G |
Golga4 |
golgin A4 |
decreases expression multiple interactions |
ISO |
Tubocurarine results in decreased expression of GOLGA4 mRNA Tubocurarine inhibits the reaction [Nicotine results in increased expression of GOLGA4 mRNA] |
CTD |
PMID:16949557 |
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NCBI chr 8:127,171,221...127,248,938
Ensembl chr 8:127,171,537...127,248,538
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine promotes the reaction [IL1B protein results in increased expression of CXCL8 mRNA]]; Tubocurarine inhibits the reaction [Nicotine promotes the reaction [IL1B protein results in increased secretion of CXCL8 protein]] |
CTD |
PMID:22119045 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Kcnn1 |
potassium calcium-activated channel subfamily N member 1 |
decreases activity |
ISO |
Tubocurarine results in decreased activity of KCNN1 protein |
CTD |
PMID:10696100 |
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NCBI chr16:20,325,270...20,349,163
Ensembl chr16:20,336,638...20,348,804
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G |
Kcnn2 |
potassium calcium-activated channel subfamily N member 2 |
decreases activity |
ISO EXP |
Tubocurarine results in decreased activity of KCNN2 protein |
CTD |
PMID:10696100 PMID:10991935 |
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NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
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G |
Kmt2c |
lysine methyltransferase 2C |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of KMT2C mRNA] Tubocurarine results in decreased expression of KMT2C mRNA |
CTD |
PMID:12588870 |
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NCBI chr 4:82,506...109,986 NCBI chr 4:6,083,650...6,294,413
Ensembl chr 4:6,083,736...6,292,516
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G |
Litaf |
lipopolysaccharide-induced TNF factor |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of LITAF mRNA] |
CTD |
PMID:12588870 |
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NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:22119045 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:22119045 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 promotes the reaction [Nicotine results in increased expression of MMP1 protein]]; Tubocurarine inhibits the reaction [Nicotine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP1 protein]]; Tubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 mRNA]; Tubocurarine inhibits the reaction [Nicotine results in increased expression of MMP1 protein] |
CTD |
PMID:17151781 PMID:18986645 |
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NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
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G |
Nin |
ninein |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of NIN mRNA] Tubocurarine results in decreased expression of NIN mRNA |
CTD |
PMID:16949557 |
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NCBI chr 6:92,423,412...92,527,776
Ensembl chr 6:92,433,381...92,527,711
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [CHRNA1 protein binds to PLAU protein] |
CTD |
PMID:19690163 |
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NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
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G |
Pou5f1 |
POU class 5 homeobox 1 |
decreases expression multiple interactions |
ISO |
Tubocurarine results in decreased expression of POU5F1 mRNA Tubocurarine inhibits the reaction [Nicotine results in increased expression of POU5F1 mRNA] |
CTD |
PMID:15612475 PMID:15749260 |
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NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
decreases expression |
ISO |
Tubocurarine results in decreased expression of PRKN mRNA |
CTD |
PMID:16949557 |
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NCBI chr 1:48,880,015...50,069,998
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G |
Ptma |
prothymosin alpha |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [PTMA protein results in decreased expression of BCL2]; Tubocurarine inhibits the reaction [PTMA protein results in increased expression of FAS] |
CTD |
PMID:16644063 |
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NCBI chr 9:93,545,396...93,549,436
Ensembl chr 9:93,545,396...93,549,436
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G |
Ptpra |
protein tyrosine phosphatase, receptor type, A |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of PTPRA mRNA] |
CTD |
PMID:12588870 |
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NCBI chr 3:122,976,066...123,084,585
Ensembl chr 3:122,976,104...123,084,863
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G |
Rbbp6 |
RB binding protein 6, ubiquitin ligase |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of RBBP6 mRNA] |
CTD |
PMID:12588870 |
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NCBI chr 1:192,933,264...192,965,160
Ensembl chr 1:192,933,540...192,965,158
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G |
Sftpa1 |
surfactant protein A1 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of SFTPA1 mRNA] |
CTD |
PMID:9458815 |
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NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
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G |
Sftpc |
surfactant protein C |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of SFTPC mRNA] |
CTD |
PMID:9458815 |
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NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
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G |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of SOS1 mRNA] Tubocurarine results in decreased expression of SOS1 mRNA |
CTD |
PMID:16949557 |
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NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of SPP1 protein] |
CTD |
PMID:11425648 |
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NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
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G |
Stip1 |
stress-induced phosphoprotein 1 |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of STIP1 mRNA] Tubocurarine results in decreased expression of STIP1 mRNA |
CTD |
PMID:16949557 |
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NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
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G |
Ube2c |
ubiquitin-conjugating enzyme E2C |
multiple interactions decreases expression |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in decreased expression of UBE2C mRNA] Tubocurarine results in decreased expression of UBE2C mRNA |
CTD |
PMID:16949557 |
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NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
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G |
Ube3a |
ubiquitin protein ligase E3A |
increases expression multiple interactions |
ISO |
Tubocurarine results in increased expression of UBE3A mRNA Tubocurarine inhibits the reaction [Nicotine results in decreased expression of UBE3A mRNA] |
CTD |
PMID:12588870 |
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NCBI chr 1:116,586,901...116,678,161
Ensembl chr 1:116,587,815...116,679,973
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
Tubocurarine inhibits the reaction [Isoflurophate results in increased expression of XDH protein alternative form] |
CTD |
PMID:9789800 |
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NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
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G |
Zfp42 |
zinc finger protein 42 |
multiple interactions |
ISO |
Tubocurarine inhibits the reaction [Nicotine results in increased expression of ZFP42 mRNA] |
CTD |
PMID:15749260 |
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NCBI chr16:52,016,590...52,026,346
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G |
Zfr |
zinc finger RNA binding protein |
decreases expression multiple interactions |
ISO |
Tubocurarine results in decreased expression of ZFR mRNA Tubocurarine inhibits the reaction [Nicotine results in decreased expression of ZFR mRNA] |
CTD |
PMID:12588870 |
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NCBI chr 2:62,150,251...62,213,048
Ensembl chr 2:62,150,251...62,213,048
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