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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Triptolide
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Accession:CHEBI:9747 term browser browse the term
Definition:An oxacycle that has formula C20H24O6.
Synonyms:related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14,16,22H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1;   InChIKey=DFBIRQPKNDILPW-CIVMWXNOSA-N;   SMILES=CC(C)[C@]12O[C@H]1[C@@H]1O[C@]11[C@]3(O[C@H]3C[C@H]3C4=C(CC[C@]13C)C(=O)OC4)[C@@H]2O
 xref: CAS:38748-32-2;   KEGG:C09204;   KNApSAcK:C00003494;   LINCS:LSM-5518
 xref_mesh: MESH:C001899
 xref: Wikipedia:Triptolide



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Triptolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin increases expression ISO triptolide results in increased expression of AAAS mRNA CTD PMID:32835833 NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961
JBrowse link
G Aadac arylacetamide deacetylase decreases expression ISO triptolide results in decreased expression of AADAC mRNA CTD PMID:32835833 NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 increases expression ISO triptolide results in increased expression of ABCA4 mRNA CTD PMID:32835833 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of ABCB11 protein
triptolide results in decreased expression of ABCB11 mRNA
CTD PMID:32519852 PMID:32987112 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
increases expression
decreases response to substance
ISO
EXP
[ABCB1A mutant form co-treated with triptolide] results in increased abundance of Malondialdehyde; ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]
triptolide results in decreased expression of ABCB1A protein
triptolide results in increased expression of ABCB1A protein
ABCB1A protein results in decreased susceptibility to triptolide
CTD PMID:26134275 PMID:32519852 PMID:33600922 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of ABCB1B mRNA
triptolide results in increased expression of ABCB1B mRNA
CTD PMID:32835833 PMID:33600922 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO triptolide results in increased expression of ABCC4 mRNA CTD PMID:32835833 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO triptolide results in decreased expression of ABCD2 mRNA CTD PMID:32835833 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression EXP triptolide results in increased expression of ABCG2 protein CTD PMID:32519852 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression ISO triptolide results in increased expression of ABHD2 mRNA CTD PMID:32835833 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase increases expression ISO triptolide results in increased expression of ABHD5 mRNA CTD PMID:32835833 NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO triptolide results in increased expression of ABTB2 mRNA CTD PMID:32835833 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression EXP triptolide results in decreased expression of ACAA1B protein CTD PMID:32519852 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation ISO triptolide results in increased phosphorylation of ACACA protein CTD PMID:29723566 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO triptolide results in decreased expression of ACACB mRNA CTD PMID:32835833 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acly ATP citrate lyase decreases expression ISO triptolide results in decreased expression of ACLY mRNA CTD PMID:32835833 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression
increases expression
ISO
EXP
triptolide results in decreased expression of ACOT1 mRNA
triptolide results in increased expression of ACOT1 protein
CTD PMID:31241159 PMID:32519852 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO triptolide results in increased expression of ACOT2 mRNA CTD PMID:32835833 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO triptolide results in increased expression of ACOT3 mRNA CTD PMID:32835833 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,723,326...103,729,482
JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression ISO triptolide results in increased expression of ACOT9 mRNA CTD PMID:32835833 NCBI chr  X:40,073,197...40,123,573
Ensembl chr  X:40,064,810...40,123,559
JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression
increases expression
ISO
EXP
triptolide results in decreased expression of ACOX2 mRNA
triptolide results in increased expression of ACOX2 protein
CTD PMID:31241159 PMID:32519852 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO triptolide results in decreased expression of ACSL5 mRNA CTD PMID:32835833 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression EXP triptolide results in decreased expression of ACSM1 protein CTD PMID:32519852 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression EXP triptolide results in decreased expression of ACSM2 protein CTD PMID:32519852 NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO triptolide results in decreased expression of ACSS2 mRNA CTD PMID:32835833 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Actb actin, beta decreases expression EXP triptolide results in decreased expression of ACTB mRNA; triptolide results in decreased expression of ACTB protein CTD PMID:27554044 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Ada adenosine deaminase increases expression EXP triptolide results in increased expression of ADA protein CTD PMID:32519852 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adam11 ADAM metallopeptidase domain 11 decreases expression ISO triptolide results in decreased expression of ADAM11 mRNA CTD PMID:32835833 NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a increases expression ISO triptolide results in increased expression of ADAM1A mRNA CTD PMID:32835833 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311
JBrowse link
G Adam2 ADAM metallopeptidase domain 2 increases expression ISO triptolide results in increased expression of ADAM2 mRNA CTD PMID:32835833 NCBI chr15:40,242,783...40,284,025
Ensembl chr15:40,242,783...40,283,952
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO triptolide results in increased expression of ADAMTS1 mRNA CTD PMID:32835833 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO triptolide results in decreased expression of ADGRF1 mRNA CTD PMID:32835833 NCBI chr 9:17,661,258...17,696,359 JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP triptolide results in decreased expression of ADH1 mRNA CTD PMID:23639586 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adpgk ADP-dependent glucokinase increases expression EXP
ISO
triptolide results in increased expression of ADPGK mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 8:59,699,400...59,727,352
Ensembl chr 8:59,699,388...59,727,351
JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO triptolide results in increased expression of AEN mRNA CTD PMID:32835833 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Afm afamin increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of AFM protein
triptolide results in decreased expression of AFM mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Afmid arylformamidase decreases expression ISO triptolide results in decreased expression of AFMID mRNA CTD PMID:32835833 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 increases expression ISO triptolide results in increased expression of AGPAT5 mRNA CTD PMID:32835833 NCBI chr16:70,939,480...70,985,761
Ensembl chr16:70,943,135...70,985,560
JBrowse link
G Agps alkylglycerone phosphate synthase increases expression EXP triptolide results in increased expression of AGPS protein CTD PMID:32519852 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO triptolide results in decreased expression of AHCY mRNA CTD PMID:32835833 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO triptolide results in decreased expression of AIFM1 protein CTD PMID:26990902 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression EXP triptolide results in increased expression of AKR1B1 protein CTD PMID:32519852 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression EXP triptolide results in decreased expression of AKR1B10 protein CTD PMID:32519852 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 increases expression EXP triptolide results in increased expression of AKR1B8 protein CTD PMID:32519852 NCBI chr 4:62,997,241...63,009,815 JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO triptolide results in decreased expression of AKR1C6 mRNA CTD PMID:32835833 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP triptolide results in increased expression of AKR7A2 protein CTD PMID:32519852 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein]
CTD PMID:21717513 PMID:32061799 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression EXP triptolide results in decreased expression of AKT2 mRNA CTD PMID:23639586 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alb albumin increases expression EXP triptolide results in increased expression of ALB protein CTD PMID:32519852 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 decreases expression ISO triptolide results in decreased expression of ALDH1L1 mRNA CTD PMID:32835833 NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP
ISO
triptolide results in decreased expression of ALDOB mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO triptolide results in decreased expression of ALDOC mRNA CTD PMID:32835833 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Amacr alpha-methylacyl-CoA racemase affects expression EXP triptolide affects the expression of AMACR protein CTD PMID:32519852 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression EXP triptolide results in increased expression of AMBP protein CTD PMID:32519852 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G Amh anti-Mullerian hormone increases expression ISO triptolide results in increased expression of AMH mRNA CTD PMID:32835833 NCBI chr 7:8,906,776...8,909,184
Ensembl chr 7:8,906,836...8,909,282
JBrowse link
G Ankmy1 ankyrin repeat and MYND domain containing 1 increases expression ISO triptolide results in increased expression of ANKMY1 mRNA CTD PMID:32835833 NCBI chr 9:93,423,664...93,476,651
Ensembl chr 9:93,423,963...93,477,236
JBrowse link
G Ankrd13a ankyrin repeat domain 13a increases expression ISO triptolide results in increased expression of ANKRD13A mRNA CTD PMID:32835833 NCBI chr12:41,798,196...41,828,327
Ensembl chr12:41,798,199...41,829,327
JBrowse link
G Ano6 anoctamin 6 increases expression EXP triptolide results in increased expression of ANO6 protein CTD PMID:32519852 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP triptolide results in increased expression of ANP32E protein CTD PMID:32519852 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054
JBrowse link
G Anpep alanyl aminopeptidase, membrane affects expression EXP triptolide affects the expression of ANPEP protein CTD PMID:32519852 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Anxa13 annexin A13 increases expression EXP triptolide results in increased expression of ANXA13 protein CTD PMID:32519852 NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907
JBrowse link
G Anxa9 annexin A9 increases expression ISO triptolide results in increased expression of ANXA9 mRNA CTD PMID:32835833 NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374
JBrowse link
G Aoc2-ps1 amine oxidase, copper containing 2, pseudogene 1 increases expression ISO triptolide results in increased expression of AOC2 mRNA CTD PMID:32835833 NCBI chr10:86,267,007...86,268,473 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression
multiple interactions
ISO
EXP
triptolide results in increased expression of APAF1 protein
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein]
CTD PMID:25169008 PMID:26990902 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 affects expression ISO triptolide affects the expression of APEX2 mRNA CTD PMID:32835833 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439
JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP triptolide results in increased expression of APOA1 protein CTD PMID:32519852 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Aqp1 aquaporin 1 increases expression EXP triptolide results in increased expression of AQP1 protein CTD PMID:32519852 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp2 aquaporin 2 increases expression EXP triptolide results in increased expression of AQP2 protein CTD PMID:32519852 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO triptolide results in decreased expression of AQP4 mRNA CTD PMID:32835833 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO triptolide results in decreased expression of AQP8 mRNA CTD PMID:32835833 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO triptolide results in increased expression of ARC mRNA CTD PMID:32835833 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arglu1 arginine and glutamate rich 1 increases expression EXP triptolide results in increased expression of ARGLU1 protein CTD PMID:32519852 NCBI chr16:80,753,300...80,777,350
Ensembl chr16:80,753,315...80,777,349
JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO triptolide results in decreased expression of ARHGEF16 mRNA CTD PMID:32835833 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212
JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 decreases expression ISO triptolide results in decreased expression of ARHGEF37 mRNA CTD PMID:32835833 NCBI chr18:54,935,256...55,001,017
Ensembl chr18:54,949,110...55,000,669
JBrowse link
G Arid1a AT-rich interaction domain 1A increases expression ISO triptolide results in increased expression of ARID1A mRNA CTD PMID:32835833 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO triptolide results in increased expression of ARID5A mRNA CTD PMID:32835833 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arl8b ADP-ribosylation factor like GTPase 8B decreases expression EXP triptolide results in decreased expression of ARL8B protein CTD PMID:32519852 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596
JBrowse link
G Armc9 armadillo repeat containing 9 increases expression EXP triptolide results in increased expression of ARMC9 protein CTD PMID:32519852 NCBI chr 9:86,802,791...86,928,860
Ensembl chr 9:86,802,868...86,928,860
JBrowse link
G Arrb1 arrestin, beta 1 increases expression EXP triptolide results in increased expression of ARRB1 protein CTD PMID:32519852 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Ascl3 achaete-scute family bHLH transcription factor 3 increases expression ISO triptolide results in increased expression of ASCL3 mRNA CTD PMID:32835833 NCBI chr 1:163,755,306...163,755,951 JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO triptolide results in decreased expression of ASGR1 mRNA CTD PMID:32835833 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO triptolide results in decreased expression of ASL mRNA CTD PMID:32835833 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP triptolide results in increased expression of ASNS protein CTD PMID:32519852 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP
ISO
triptolide results in decreased expression of ASS1 protein
triptolide results in decreased expression of ASS1 mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO triptolide results in increased expression of ATF3 mRNA CTD PMID:32835833 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 decreases expression EXP triptolide results in decreased expression of ATF4 mRNA CTD PMID:23639586 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO triptolide results in decreased expression of ATF5 mRNA CTD PMID:32835833 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 decreases expression ISO triptolide results in decreased expression of ATF6 protein CTD PMID:26990902 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO triptolide results in decreased expression of ATF6B protein CTD PMID:26990902 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
JBrowse link
G Atg12 autophagy related 12 increases expression ISO triptolide results in increased expression of ATG12 protein CTD PMID:26990902 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 increases expression ISO triptolide results in increased expression of ATG5 protein CTD PMID:26990902 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 increases expression ISO triptolide results in increased expression of ATG7 protein CTD PMID:26990902 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp11a ATPase phospholipid transporting 11A increases expression EXP triptolide results in increased expression of ATP11A protein CTD PMID:32519852 NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP triptolide results in decreased expression of ATP5E protein CTD PMID:32519852 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression EXP triptolide results in increased expression of ATP5G3 protein CTD PMID:32519852 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression EXP triptolide results in increased expression of ATP5I protein CTD PMID:32519852 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp5mj ATP synthase membrane subunit j decreases expression EXP triptolide results in decreased expression of ATP5MJ protein CTD PMID:32519852
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression EXP triptolide results in increased expression of ATP6V0A1 protein CTD PMID:32519852 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression EXP triptolide results in increased expression of ATP6V0A4 protein CTD PMID:32519852 NCBI chr 4:66,760,159...66,842,110
Ensembl chr 4:66,760,159...66,842,110
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression EXP triptolide results in increased expression of ATP6V0C protein CTD PMID:32519852 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 increases expression EXP triptolide results in increased expression of ATP6V0D1 protein CTD PMID:32519852 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO triptolide results in increased expression of B4GALT1 mRNA CTD PMID:32835833 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461
JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO triptolide results in increased expression of BAG3 mRNA CTD PMID:32835833 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO triptolide results in increased expression of BAIAP3 mRNA CTD PMID:32835833 NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP
ISO
pifithrin inhibits the reaction [triptolide results in increased expression of BAK1 protein]
TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAK1 protein]
CTD PMID:30009776 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects expression
EXP
ISO
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of BAX protein]; pifithrin inhibits the reaction [triptolide results in increased expression of BAX protein]; Quercetin inhibits the reaction [triptolide affects the expression of BAX protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of BAX protein]
triptolide results in increased expression of BAX mRNA; triptolide results in increased expression of BAX protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in increased expression of BAX protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]; tariquidar promotes the reaction [triptolide results in increased expression of BAX protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAX protein]
CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP triptolide results in increased expression of BBC3 protein CTD PMID:30009776 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
affects expression
EXP
ISO
triptolide results in decreased expression of BCL2 protein
triptolide results in increased expression of BCL2 protein
ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; tariquidar promotes the reaction [triptolide results in decreased expression of BCL2 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
triptolide affects the expression of BCL2 protein
Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; Quercetin inhibits the reaction [triptolide affects the expression of BCL2 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 More... NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
ISO
EXP
triptolide results in increased expression of BCL2L1 protein
triptolide results in decreased expression of BCL2L1 protein
TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]
pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]
CTD PMID:26990902 PMID:30009776 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l14 BCL2 like 14 increases expression ISO triptolide results in increased expression of BCL2L14 mRNA CTD PMID:32835833 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO triptolide results in decreased expression of BDH2 mRNA CTD PMID:32835833 NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
JBrowse link
G Becn1 beclin 1 increases expression ISO triptolide results in increased expression of BECN1 protein CTD PMID:26990902 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bfsp1 beaded filament structural protein 1 increases expression ISO triptolide results in increased expression of BFSP1 mRNA CTD PMID:32835833 NCBI chr 3:131,195,087...131,252,668
Ensembl chr 3:131,195,087...131,229,337
JBrowse link
G Bhlhb9 basic helix-loop-helix family member B9 decreases expression ISO triptolide results in decreased expression of BHLHB9 mRNA CTD PMID:32835833 NCBI chr  X:98,820,289...98,854,949
Ensembl chr  X:98,817,593...98,854,545
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO triptolide results in decreased expression of BHLHE40 mRNA CTD PMID:32835833 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO triptolide results in increased expression of BID protein CTD PMID:26990902 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO triptolide results in decreased expression of BIRC3 mRNA CTD PMID:15972136 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Blvra biliverdin reductase A affects expression EXP triptolide affects the expression of BLVRA protein CTD PMID:32519852 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033
JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO triptolide results in decreased expression of BMF mRNA CTD PMID:32835833 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression ISO triptolide results in increased expression of BOP1 mRNA CTD PMID:32835833 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931
JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta decreases expression EXP triptolide results in decreased expression of BSND protein CTD PMID:32519852 NCBI chr 5:121,251,774...121,260,571
Ensembl chr 5:121,251,774...121,260,571
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression EXP triptolide results in increased expression of BST2 protein CTD PMID:32519852 NCBI chr16:18,217,404...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Btaf1 B-TFIID TATA-box binding protein associated factor 1 increases expression ISO triptolide results in increased expression of BTAF1 mRNA CTD PMID:32835833 NCBI chr 1:234,653,219...234,743,903
Ensembl chr 1:234,653,156...234,743,903
JBrowse link
G Btbd10 BTB domain containing 10 increases expression ISO triptolide results in increased expression of BTBD10 mRNA CTD PMID:32835833 NCBI chr 1:167,431,320...167,489,320
Ensembl chr 1:167,431,329...167,489,916
JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO triptolide results in increased expression of BTG3 mRNA CTD PMID:32835833 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170
JBrowse link
G Btnl9 butyrophilin-like 9 increases expression ISO triptolide results in increased expression of BTNL9 mRNA CTD PMID:32835833 NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression
increases expression
EXP triptolide results in decreased expression of BUB1 mRNA
triptolide results in increased expression of BUB1 mRNA
CTD PMID:23639586 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP triptolide results in increased expression of BUB1B mRNA CTD PMID:23639586 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression EXP triptolide results in decreased expression of BUB3 mRNA CTD PMID:23639586 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036
JBrowse link
G C1qa complement C1q A chain increases expression EXP triptolide results in increased expression of C1QA protein CTD PMID:32519852 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C3 complement C3 increases expression EXP triptolide results in increased expression of C3 protein CTD PMID:32519852 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G C4a complement C4A increases expression EXP triptolide results in increased expression of C4A protein CTD PMID:32519852 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO triptolide results in decreased expression of CAR14 mRNA CTD PMID:32835833 NCBI chr 2:183,442,263...183,449,207
Ensembl chr 2:183,441,667...183,449,693
JBrowse link
G Ca3 carbonic anhydrase 3 increases expression EXP triptolide results in increased expression of CA3 protein CTD PMID:32519852 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein] CTD PMID:24842335 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 decreases expression ISO triptolide results in decreased expression of CABCOCO1 mRNA CTD PMID:32835833 NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725
JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO triptolide results in increased expression of CABYR mRNA CTD PMID:32835833 NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840
JBrowse link
G Cald1 caldesmon 1 decreases expression EXP triptolide results in decreased expression of CALD1 protein CTD PMID:32519852 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO triptolide results in increased expression of CAMTA2 mRNA CTD PMID:32835833 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
JBrowse link
G Capg capping actin protein, gelsolin like increases expression EXP triptolide results in increased expression of CAPG protein CTD PMID:32519852 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Capn1 calpain 1 increases expression ISO triptolide results in increased expression of CAPN1 protein CTD PMID:26990902 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Capn2 calpain 2 increases expression ISO triptolide results in increased expression of CAPN2 protein CTD PMID:26990902 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
JBrowse link
G Caps calcyphosine increases expression ISO triptolide results in increased expression of TNFRSF23 mRNA CTD PMID:32835833 NCBI chr 9:1,544,597...1,545,631 JBrowse link
G Car1 carbonic anhydrase 1 increases expression EXP triptolide results in increased expression of CA1 protein CTD PMID:32519852 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Carf calcium responsive transcription factor increases expression ISO triptolide results in increased expression of CARF mRNA CTD PMID:32835833 NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP triptolide results in decreased expression of CARHSP1 protein CTD PMID:32519852 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO triptolide results in decreased expression of LRRC16A mRNA CTD PMID:32835833 NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326
JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 increases expression ISO triptolide results in increased expression of RLTPR mRNA CTD PMID:32835833 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Casp12 caspase 12 increases expression ISO triptolide results in increased expression of CASP12 protein CTD PMID:26990902 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
triptolide results in increased activity of and results in increased cleavage of CASP3 protein
triptolide results in increased cleavage of CASP3 protein
triptolide results in increased expression of CASP3 protein modified form
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of CASP3 protein modified form]; triptolide results in increased expression of and results in increased activity of CASP3 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
triptolide results in increased activity of CASP3 protein
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP3 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
CTD PMID:12533674 PMID:15972136 PMID:19233258 PMID:21640813 PMID:23639586 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity
increases expression
ISO
EXP
triptolide results in increased activity of CASP7 protein
triptolide results in increased expression of CASP7 protein
CTD PMID:21640813 PMID:32519852 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form; triptolide results in increased expression of and results in increased activity of CASP8 protein CTD PMID:26990902 PMID:30633930 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
increases activity
EXP
ISO
pifithrin inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP9 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]
triptolide results in increased cleavage of CASP9 protein
triptolide results in increased expression of and results in increased activity of CASP9 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]
CTD PMID:26277538 PMID:26990902 PMID:30009776 PMID:32835833 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression EXP triptolide results in increased expression of CASTOR1 protein CTD PMID:32519852 NCBI chr14:79,086,136...79,090,549
Ensembl chr14:79,086,136...79,090,548
JBrowse link
G Cav1 caveolin 1 increases expression EXP triptolide results in increased expression of CAV1 protein CTD PMID:32519852 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression ISO triptolide results in increased expression of CBARP mRNA CTD PMID:32835833 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP triptolide results in decreased expression of CBLC mRNA CTD PMID:23639586 NCBI chr 1:79,439,975...79,456,755
Ensembl chr 1:79,439,977...79,456,755
JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO triptolide results in increased expression of CBR3 mRNA CTD PMID:32835833 NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
JBrowse link
G Ccdc120 coiled-coil domain containing 120 increases expression ISO triptolide results in increased expression of CCDC120 mRNA CTD PMID:32835833 NCBI chr  X:14,753,594...14,772,745
Ensembl chr  X:14,753,696...14,772,743
JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression ISO triptolide results in increased expression of CCDC15 mRNA CTD PMID:32835833 NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919
JBrowse link
G Ccdc180 coiled-coil domain containing 180 increases expression ISO triptolide results in increased expression of CCDC180 mRNA CTD PMID:32835833 NCBI chr 5:60,154,883...60,223,508
Ensembl chr 5:60,154,910...60,223,522
JBrowse link
G Ccdc196 coiled-coil domain containing 196 increases expression EXP triptolide results in increased expression of CCDC196 protein CTD PMID:32519852 NCBI chr 6:96,913,960...96,939,415
Ensembl chr 6:96,915,869...96,931,141
JBrowse link
G Ccdc62 coiled-coil domain containing 62 increases expression ISO triptolide results in increased expression of CCDC62 mRNA CTD PMID:32835833 NCBI chr12:32,623,170...32,659,912
Ensembl chr12:32,623,170...32,660,017
JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression ISO triptolide results in increased expression of CCDC86 mRNA CTD PMID:32835833 NCBI chr 1:207,590,946...207,596,527
Ensembl chr 1:207,590,168...207,596,544
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
multiple interactions
ISO triptolide results in increased expression of CCL11 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]
CTD PMID:24949944 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO triptolide promotes the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
triptolide results in increased expression of CCL2 mRNA
CTD PMID:30633930 PMID:32835833 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccna1 cyclin A1 decreases expression ISO triptolide results in decreased expression of CCNA1 protein CTD PMID:12533674 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
JBrowse link
G Ccna2 cyclin A2 increases expression EXP triptolide results in increased expression of CCNA2 mRNA CTD PMID:23639586 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CCNB1 mRNA
triptolide results in decreased expression of CCNB1 protein
CTD PMID:12533674 PMID:23639586 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases expression EXP triptolide results in increased expression of CCNB2 mRNA CTD PMID:23639586 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP
ISO
triptolide results in decreased expression of CCND1 mRNA
triptolide results in decreased expression of CCND1 protein
CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 increases expression EXP triptolide results in increased expression of CCND2 mRNA CTD PMID:23639586 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccne1 cyclin E1 increases expression ISO triptolide results in increased expression of CCNE1 protein CTD PMID:26990902 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 increases expression EXP triptolide results in increased expression of CCNE2 mRNA CTD PMID:23639586 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng1 cyclin G1 increases expression ISO triptolide results in increased expression of CCNG1 mRNA CTD PMID:32835833 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd24 CD24 molecule multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD24 protein] CTD PMID:24842335 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd36 CD36 molecule increases expression EXP triptolide results in increased expression of CD36 protein CTD PMID:32519852 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD44 protein] CTD PMID:24842335 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd47 Cd47 molecule increases expression EXP triptolide results in increased expression of CD47 protein CTD PMID:32519852 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd59 CD59 molecule increases expression EXP triptolide results in increased expression of CD59 protein CTD PMID:32519852 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein] CTD PMID:15663903 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein] CTD PMID:15663903 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc16 cell division cycle 16 decreases expression EXP triptolide results in decreased expression of CDC16 mRNA CTD PMID:23639586 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550
JBrowse link
G Cdc25b cell division cycle 25B increases expression EXP triptolide results in increased expression of CDC25B mRNA CTD PMID:23639586 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc42 cell division cycle 42 decreases expression EXP triptolide results in decreased expression of CDC42 mRNA; triptolide results in decreased expression of CDC42 protein CTD PMID:27554044 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc45 cell division cycle 45 increases expression EXP triptolide results in increased expression of CDC45 mRNA CTD PMID:23639586 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CDK1 mRNA
triptolide results in decreased expression of CDK1 protein
CTD PMID:12533674 PMID:23639586 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of CDK2 mRNA
triptolide results in decreased expression of CDK2 protein
triptolide results in increased expression of CDK2 protein
CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO triptolide results in increased expression of CDK4 protein CTD PMID:26990902 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO triptolide results in increased expression of CDK6 protein CTD PMID:26990902 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression EXP triptolide results in increased expression of CDK7 mRNA CTD PMID:23639586 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO triptolide results in increased expression of CDKL3 mRNA CTD PMID:32835833 NCBI chr10:36,263,212...36,349,268
Ensembl chr10:36,266,977...36,349,268
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP
ISO
triptolide results in increased expression of CDKN1A mRNA
triptolide results in increased expression of CDKN1A mRNA; triptolide results in increased expression of CDKN1A protein
CTD PMID:23639586 PMID:26990902 PMID:32835833 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP triptolide results in increased expression of CDKN1B protein CTD PMID:32519852 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP triptolide results in increased expression of CDKN2C mRNA CTD PMID:23639586 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression ISO triptolide results in increased expression of CDNF mRNA CTD PMID:32835833 NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639
JBrowse link
G Cep170b centrosomal protein 170B increases expression ISO triptolide results in increased expression of CEP170B mRNA CTD PMID:32835833 NCBI chr 6:131,780,935...131,806,658
Ensembl chr 6:131,778,957...131,806,658
JBrowse link
G Cep63 centrosomal protein 63 increases expression ISO triptolide results in increased expression of CEP63 mRNA CTD PMID:32835833 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177
JBrowse link
G Ces1a carboxylesterase 1A increases expression ISO triptolide results in increased expression of CES1A mRNA CTD PMID:32835833 NCBI chr19:13,959,529...13,986,370
Ensembl chr19:13,959,482...13,986,370
JBrowse link
G Ces1d carboxylesterase 1D increases expression EXP triptolide results in increased expression of CES1D protein CTD PMID:32519852 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces4a carboxylesterase 4A decreases expression ISO triptolide results in decreased expression of CES4A mRNA CTD PMID:32835833 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545
JBrowse link
G Cfap20dc CFAP20 domain containing decreases expression ISO triptolide results in decreased expression of CFAP20DC mRNA CTD PMID:32835833 NCBI chr15:16,231,248...16,476,978
Ensembl chr15:16,231,299...16,476,977
JBrowse link
G Cfb complement factor B decreases expression ISO triptolide results in decreased expression of CFB mRNA CTD PMID:32835833 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Cfh complement factor H increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CFH protein
triptolide results in decreased expression of CFH mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Cfl2 cofilin 2 increases expression EXP triptolide results in increased expression of CFL2 protein CTD PMID:32519852 NCBI chr 6:72,355,664...72,359,709
Ensembl chr 6:72,355,664...72,359,674
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 increases expression EXP triptolide results in increased expression of CHCHD3 protein CTD PMID:32519852 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP triptolide results in increased expression of CHCHD6 protein CTD PMID:32519852 NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
JBrowse link
G Chka choline kinase alpha increases expression ISO triptolide results in increased expression of CHKA mRNA CTD PMID:32835833 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO triptolide results in decreased expression of CHRNA4 mRNA CTD PMID:32835833 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Ciart circadian associated repressor of transcription decreases expression ISO triptolide results in decreased expression of CIART mRNA CTD PMID:32835833 NCBI chr 2:183,419,819...183,424,845
Ensembl chr 2:183,419,819...183,423,313
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression ISO triptolide results in increased expression of CIDEC mRNA CTD PMID:32835833 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO triptolide results in increased expression of CKAP2 mRNA CTD PMID:32835833 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO triptolide results in increased expression of CLCF1 mRNA CTD PMID:32835833 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Clcnkb chloride voltage-gated channel Kb increases expression EXP triptolide results in increased expression of CLCNKB protein CTD PMID:32519852 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions
ISO triptolide results in decreased expression of CLDN11 mRNA; triptolide results in decreased expression of CLDN11 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of CLDN11 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of CLDN11 protein]
CTD PMID:30836114 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO triptolide results in increased expression of CLEC11A mRNA CTD PMID:32835833 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633
JBrowse link
G Clmn calmin decreases expression ISO triptolide results in decreased expression of CLMN mRNA CTD PMID:32835833 NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X affects expression ISO triptolide affects the expression of CLPX mRNA CTD PMID:32835833 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Clu clusterin increases expression EXP triptolide results in increased expression of CLU protein CTD PMID:32519852 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cluap1 clusterin associated protein 1 increases expression ISO triptolide results in increased expression of CLUAP1 mRNA CTD PMID:32835833 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711
JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene decreases expression ISO triptolide results in decreased expression of CMAH mRNA CTD PMID:32835833 NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression EXP triptolide results in increased expression of CMPK2 protein CTD PMID:32519852 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression EXP triptolide results in decreased expression of CNBP protein CTD PMID:32519852 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CNP protein
triptolide results in decreased expression of CNP mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Cog5 component of oligomeric golgi complex 5 decreases expression EXP triptolide results in decreased expression of COG5 protein CTD PMID:32519852 NCBI chr 6:48,242,470...48,545,185
Ensembl chr 6:48,242,482...48,529,009
JBrowse link
G Col11a2 collagen type XI alpha 2 chain increases expression ISO triptolide results in increased expression of COL11A2 mRNA CTD PMID:32835833 NCBI chr20:4,786,929...4,816,598
Ensembl chr20:4,786,929...4,815,985
JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression ISO triptolide results in increased expression of COL12A1 mRNA CTD PMID:32835833 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col20a1 collagen type XX alpha 1 chain increases expression ISO triptolide results in increased expression of COL20A1 mRNA CTD PMID:32835833 NCBI chr 3:168,102,475...168,134,759
Ensembl chr 3:168,084,560...168,135,309
JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression ISO triptolide results in increased expression of COL7A1 mRNA CTD PMID:32835833 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP triptolide results in decreased expression of COMT protein CTD PMID:32519852 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cp ceruloplasmin increases expression EXP triptolide results in increased expression of CP protein CTD PMID:32519852 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression ISO triptolide results in decreased expression of CPS1 mRNA CTD PMID:32835833 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033
JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 decreases expression EXP triptolide results in decreased expression of CPSF2 protein CTD PMID:32519852 NCBI chr 6:121,123,941...121,152,756
Ensembl chr 6:121,120,569...121,151,921
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO triptolide results in increased expression of CPT1A mRNA CTD PMID:29723566 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO triptolide results in decreased expression of CPT1B mRNA CTD PMID:31241159 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO triptolide results in decreased expression of CPT2 mRNA CTD PMID:31241159 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crbn cereblon increases expression EXP triptolide results in increased expression of CRBN protein CTD PMID:32519852 NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression ISO triptolide results in increased expression of CREB3L4 mRNA CTD PMID:32835833 NCBI chr 2:175,690,340...175,696,084
Ensembl chr 2:175,690,335...175,695,932
JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP triptolide results in decreased expression of CREM mRNA CTD PMID:23639586 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crip2 cysteine-rich protein 2 increases expression ISO triptolide results in increased expression of CRIP2 mRNA CTD PMID:32835833 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression
increases expression
EXP triptolide results in decreased expression of CRK mRNA
triptolide results in increased expression of CRK mRNA
CTD PMID:23639586 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406
JBrowse link
G Crp C-reactive protein increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of CRP protein
triptolide results in decreased expression of CRP mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression ISO triptolide results in increased expression of CRY1 mRNA CTD PMID:32835833 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cryab crystallin, alpha B increases expression ISO triptolide results in increased expression of CRYAB mRNA CTD PMID:32835833 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 decreases expression ISO triptolide results in decreased expression of CSPG5 mRNA CTD PMID:32835833 NCBI chr 8:110,220,653...110,234,750
Ensembl chr 8:110,220,653...110,234,758
JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO triptolide results in decreased expression of CTF1 mRNA CTD PMID:32835833 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
JBrowse link
G Ctps1 CTP synthase 1 increases expression ISO triptolide results in increased expression of CTPS mRNA CTD PMID:32835833 NCBI chr 5:134,125,022...134,154,155
Ensembl chr 5:134,125,025...134,154,180
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 affects expression ISO triptolide affects the expression of CXCL11 mRNA CTD PMID:32835833 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
ISO triptolide results in increased expression of CXCL2 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]
CTD PMID:24949944 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein] CTD PMID:20348278 PMID:24949944 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO triptolide results in decreased expression of CXCR4 protein CTD PMID:26420756 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression ISO triptolide results in decreased expression of CYB5R3 mRNA CTD PMID:32835833 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
triptolide results in decreased expression of and results in decreased activity of CYP11A1 protein
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA
triptolide results in decreased expression of CYP11A1 mRNA
CTD PMID:22592319 PMID:31557376 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA CTD PMID:31557376 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA
triptolide results in decreased expression of CYP17A1 mRNA
CTD PMID:31557376 PMID:32835833 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO triptolide affects the expression of CYP26A1 mRNA CTD PMID:32835833 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP27A1 mRNA CTD PMID:32987112 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO triptolide results in increased expression of CYP27B1 mRNA CTD PMID:32835833 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2A1 mRNA] CTD PMID:32987112 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
ISO
EXP
TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2B10 mRNA]
triptolide results in decreased expression of CYP2B1 mRNA
CTD PMID:32835833 PMID:32987112 PMID:33600922 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP triptolide results in decreased expression of CYP2C11 protein CTD PMID:32519852 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression EXP
ISO
triptolide results in decreased expression of CYP2C8 protein
triptolide results in decreased expression of CYP2C29 mRNA
CTD PMID:32835833 PMID:33600922
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP39A1 mRNA CTD PMID:32835833 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
decreases expression
EXP CYP3A2 affects the metabolism of triptolide
triptolide results in decreased expression of CYP3A4 protein
CTD PMID:20223271 PMID:33600922 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
decreases activity
EXP triptolide results in decreased expression of CYP3A23-3A1 mRNA
triptolide results in decreased activity of CYP3A23-3A1 protein
CTD PMID:33600922 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP4F14 mRNA CTD PMID:32835833 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO triptolide results in decreased expression of CYP51 mRNA CTD PMID:32835833 NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression
ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP7A1 mRNA] CTD PMID:32987112 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
decreases expression
ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP8B1 mRNA] CTD PMID:32835833 PMID:32987112 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO triptolide results in decreased expression of DBP mRNA CTD PMID:32835833 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dclk3 doublecortin-like kinase 3 decreases expression ISO triptolide results in decreased expression of DCLK3 mRNA CTD PMID:32835833 NCBI chr 8:111,401,544...111,453,999
Ensembl chr 8:111,401,358...111,453,999
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression ISO triptolide results in increased expression of DDIAS mRNA CTD PMID:32835833 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO triptolide results in increased expression of DDIT3 protein CTD PMID:26990902 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO triptolide results in increased expression of DDIT4L mRNA CTD PMID:32835833 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Ddrgk1 DDRGK domain containing 1 decreases expression EXP triptolide results in decreased expression of DDRGK1 protein CTD PMID:32519852 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO triptolide results in increased expression of DDX17 mRNA CTD PMID:32835833 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Defb1 defensin beta 1 decreases expression ISO triptolide results in decreased expression of DEFB1 mRNA CTD PMID:32835833 NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
JBrowse link
G Dennd1a DENN domain containing 1A increases expression EXP triptolide results in increased expression of DENND1A protein CTD PMID:32519852 NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062
JBrowse link
G Depp1 DEPP1, autophagy regulator decreases expression ISO triptolide results in decreased expression of DEPP1 mRNA CTD PMID:32835833 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Des desmin multiple interactions EXP triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein] CTD PMID:18509322 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dglucy D-glutamate cyclase decreases expression EXP triptolide results in decreased expression of DGLUCY protein CTD PMID:32519852 NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO triptolide results in decreased expression of DHCR7 mRNA CTD PMID:32835833 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO triptolide results in decreased expression of DHRS7 mRNA CTD PMID:32835833 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B increases expression EXP triptolide results in increased expression of DHRS7B protein CTD PMID:32519852 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Dhrs7l1 dehydrogenase/reductase (SDR family) member 7-like 1 decreases expression EXP triptolide results in decreased expression of DHRS7L1 protein CTD PMID:32519852 NCBI chr 6:91,289,200...91,312,010
Ensembl chr 6:91,289,200...91,312,010
JBrowse link
G Dhx29 DExH-box helicase 29 increases expression ISO triptolide results in increased expression of DHX29 mRNA CTD PMID:32835833 NCBI chr 2:44,560,653...44,611,450
Ensembl chr 2:44,560,714...44,611,445
JBrowse link
G Dhx37 DEAH-box helicase 37 increases expression ISO triptolide results in increased expression of DHX37 mRNA CTD PMID:32835833 NCBI chr12:31,194,782...31,214,890
Ensembl chr12:31,194,859...31,216,802
JBrowse link
G Dhx38 DEAH-box helicase 38 increases expression ISO triptolide results in increased expression of DHX38 mRNA CTD PMID:32835833 NCBI chr19:37,512,891...37,530,140
Ensembl chr19:37,512,891...37,530,140
JBrowse link
G Dhx58 DEXH-box helicase 58 increases expression EXP triptolide results in increased expression of DHX58 protein CTD PMID:32519852 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO triptolide results in decreased expression of DIO1 mRNA CTD PMID:32835833 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dixdc1 DIX domain containing 1 decreases expression ISO triptolide results in decreased expression of DIXDC1 mRNA CTD PMID:32835833 NCBI chr 8:51,007,835...51,081,191
Ensembl chr 8:51,007,838...51,081,090
JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 increases expression ISO triptolide results in increased expression of DNAH10 mRNA CTD PMID:32835833 NCBI chr12:31,823,451...31,946,857 JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 increases expression ISO triptolide results in increased expression of DNAH5 mRNA CTD PMID:32835833 NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890
JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 increases expression ISO triptolide results in increased expression of CASC1 mRNA CTD PMID:32835833 NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980
JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression EXP triptolide results in increased expression of DNAJB12 protein CTD PMID:32519852 NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 decreases expression EXP triptolide results in decreased expression of DNAJC6 protein CTD PMID:32519852 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
JBrowse link
G Dnhd1 dynein heavy chain domain 1 increases expression ISO triptolide results in increased expression of DNHD1 mRNA CTD PMID:32835833 NCBI chr 1:159,990,785...160,077,990
Ensembl chr 1:159,990,438...160,074,858
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
ISO 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of DNM1L protein] CTD PMID:30836114 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dpep1 dipeptidase 1 increases expression EXP triptolide results in increased expression of DPEP1 protein CTD PMID:32519852 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP triptolide affects the expression of DPP4 protein CTD PMID:32519852 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 decreases expression EXP triptolide results in decreased expression of DTNBP1 protein CTD PMID:32519852 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO triptolide results in increased expression of DTX4 mRNA CTD PMID:32835833 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO triptolide results in decreased expression of DUSP1 protein CTD PMID:17507666 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression EXP triptolide results in increased expression of DYNC2H1 protein CTD PMID:32519852 NCBI chr 8:4,189,257...4,412,183
Ensembl chr 8:4,189,257...4,412,183
JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO triptolide results in increased expression of DYNLL1 mRNA CTD PMID:32835833 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G E2f1 E2F transcription factor 1 increases expression EXP triptolide results in increased expression of E2F1 mRNA CTD PMID:23639586 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G E2f3 E2F transcription factor 3 increases expression EXP triptolide results in increased expression of E2F3 mRNA CTD PMID:23639586 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO triptolide results in increased expression of EARS2 mRNA CTD PMID:32835833 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO triptolide results in decreased expression of ECHDC1 mRNA CTD PMID:32835833 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319
JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression EXP triptolide results in decreased expression of ECHDC2 protein CTD PMID:32519852 NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO triptolide results in increased expression of EDA2R mRNA CTD PMID:32835833 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression ISO triptolide results in increased expression of EEF1E1 mRNA CTD PMID:32835833 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Efnb3 ephrin B3 increases expression ISO triptolide results in increased expression of EFNB3 mRNA CTD PMID:32835833 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO triptolide results in decreased expression of EGFR mRNA CTD PMID:32835833 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Ehd2 EH-domain containing 2 increases expression EXP triptolide results in increased expression of EHD2 protein CTD PMID:32519852 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO triptolide results in increased expression of EHHADH mRNA CTD PMID:29723566 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases expression EXP triptolide results in increased expression of EIF2AK2 protein CTD PMID:32519852 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta increases expression EXP triptolide results in increased expression of EIF2B4 protein CTD PMID:32519852 NCBI chr 6:25,183,177...25,188,832
Ensembl chr 6:25,183,186...25,188,829
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO triptolide results in increased expression of EIF4E mRNA CTD PMID:32835833 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 decreases expression ISO triptolide results in decreased expression of EIF4EBP3 mRNA CTD PMID:32835833 NCBI chr18:28,263,089...28,268,033 JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 increases expression EXP triptolide results in increased expression of EIPR1 protein CTD PMID:32519852 NCBI chr 6:45,388,451...45,502,089
Ensembl chr 6:45,388,376...45,502,083
JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO triptolide results in increased expression of ELF3 mRNA CTD PMID:32835833 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 decreases expression ISO triptolide results in decreased expression of ELOVL2 mRNA CTD PMID:32835833 NCBI chr17:23,544,520...23,584,855
Ensembl chr17:23,544,568...23,584,848
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO triptolide results in decreased expression of ELOVL5 mRNA CTD PMID:32835833 NCBI chr 8:78,790,799...78,857,307
Ensembl chr 8:78,790,846...78,857,284
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO triptolide results in decreased expression of ELOVL6 mRNA CTD PMID:32835833 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Emc3 ER membrane protein complex subunit 3 increases expression EXP triptolide results in increased expression of EMC3 protein CTD PMID:32519852 NCBI chr 4:146,663,065...146,678,976
Ensembl chr 4:146,663,067...146,679,029
JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP triptolide results in increased expression of EMC8 protein CTD PMID:32519852 NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543
JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 increases expression ISO triptolide results in increased expression of EME2 mRNA CTD PMID:32835833 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO triptolide results in increased expression of ENC1 mRNA CTD PMID:32835833 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Endod1 endonuclease domain containing 1 increases expression ISO triptolide results in increased expression of ENDOD1 mRNA CTD PMID:32835833 NCBI chr 8:11,209,123...11,238,680 JBrowse link
G Endog endonuclease G increases expression ISO triptolide results in increased expression of ENDOG protein CTD PMID:26990902 NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
JBrowse link
G Eno3 enolase 3 increases expression ISO triptolide results in increased expression of ENO3 mRNA CTD PMID:32835833 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP triptolide affects the expression of ENPEP protein CTD PMID:32519852 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Erlin1 ER lipid raft associated 1 increases expression EXP triptolide results in increased expression of ERLIN1 protein CTD PMID:32519852 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression EXP triptolide results in increased expression of ERMP1 protein CTD PMID:32519852 NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression EXP triptolide results in increased expression of ESPL1 mRNA CTD PMID:23639586 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Esrrb estrogen-related receptor beta increases expression EXP triptolide results in increased expression of ESRRB protein CTD PMID:32519852 NCBI chr 6:106,007,662...106,163,136
Ensembl chr 6:106,008,095...106,160,791
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO triptolide results in increased expression of EXOC4 mRNA CTD PMID:32835833 NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723
JBrowse link
G Exosc9 exosome component 9 increases expression ISO triptolide results in increased expression of EXOSC9 mRNA CTD PMID:32835833 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO triptolide results in decreased expression of EZH2 protein CTD PMID:19879315 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G F11 coagulation factor XI decreases expression ISO triptolide results in decreased expression of F11 mRNA CTD PMID:32835833 NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression ISO triptolide results in increased expression of F2RL3 mRNA CTD PMID:32835833 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G F5 coagulation factor V increases expression EXP triptolide results in increased expression of F5 protein CTD PMID:32519852 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G F9 coagulation factor IX increases expression EXP triptolide results in increased expression of F9 protein CTD PMID:32519852 NCBI chr  X:138,352,334...138,396,835
Ensembl chr  X:138,352,298...138,396,835
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO triptolide results in decreased expression of FABP1 mRNA CTD PMID:32835833 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP triptolide results in increased expression of FABP4 protein CTD PMID:32519852 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO triptolide results in decreased expression of FABP5 mRNA CTD PMID:32835833 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO triptolide results in decreased expression of FADS1 mRNA CTD PMID:32835833 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO triptolide results in decreased expression of FADS2 mRNA CTD PMID:32835833 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO triptolide results in decreased expression of FAM107A mRNA CTD PMID:32835833 NCBI chr15:16,608,362...16,630,398
Ensembl chr15:16,607,205...16,630,396
JBrowse link
G Fam161b FAM161 centrosomal protein B increases expression ISO triptolide results in increased expression of FAM161B mRNA CTD PMID:32835833 NCBI chr 6:103,990,603...104,007,754
Ensembl chr 6:103,992,170...104,018,776
JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP triptolide results in increased expression of FAM210B protein CTD PMID:32519852 NCBI chr 3:161,118,228...161,128,400
Ensembl chr 3:161,118,239...161,128,397
JBrowse link
G Fam47e family with sequence similarity 47, member E decreases expression ISO triptolide results in decreased expression of FAM47E mRNA CTD PMID:32835833 NCBI chr14:15,485,537...15,521,599 JBrowse link
G Fam71e1 family with sequence similarity 71, member E1 increases expression ISO triptolide results in increased expression of FAM71E1 mRNA CTD PMID:32835833 NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO triptolide results in increased expression of FAM83H mRNA CTD PMID:32835833 NCBI chr 7:107,716,431...107,724,619
Ensembl chr 7:107,716,431...107,728,672
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO triptolide results in increased expression of FAS protein CTD PMID:26990902 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]
triptolide results in increased expression of FASL mRNA; triptolide results in increased expression of FASL protein
CTD PMID:24949944 PMID:26990902 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fasn fatty acid synthase decreases expression ISO triptolide results in decreased expression of FASN mRNA CTD PMID:32835833 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbn2 fibrillin 2 decreases expression EXP triptolide results in decreased expression of FBN2 protein CTD PMID:32519852 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression EXP triptolide results in decreased expression of FBP2 mRNA CTD PMID:23639586 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP triptolide results in increased expression of FBXL4 protein CTD PMID:32519852 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443
JBrowse link
G Fbxo7 F-box protein 7 increases expression EXP triptolide results in increased expression of FBXO7 protein CTD PMID:32519852 NCBI chr 7:17,809,224...17,837,549
Ensembl chr 7:17,809,231...17,837,530
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP triptolide results in increased expression of FDFT1 protein CTD PMID:32519852 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO triptolide results in decreased expression of FDPS mRNA CTD PMID:32835833 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fetub fetuin B increases expression EXP triptolide results in increased expression of FETUB protein CTD PMID:32519852 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135
JBrowse link
G Ffar4 free fatty acid receptor 4 increases expression ISO triptolide results in increased expression of FFAR4 mRNA CTD PMID:32835833 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597
JBrowse link
G Fga fibrinogen alpha chain increases expression EXP triptolide results in increased expression of FGA protein CTD PMID:32519852 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain increases expression EXP triptolide results in increased expression of FGB protein CTD PMID:32519852 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression EXP triptolide results in decreased expression of FGF1 protein CTD PMID:32519852 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression ISO triptolide results in decreased expression of FGFRL1 mRNA CTD PMID:32835833 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928
JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP triptolide results in increased expression of FGG protein CTD PMID:32519852 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fjx1 four-jointed box kinase 1 increases expression EXP triptolide results in increased expression of FJX1 protein CTD PMID:32519852 NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO triptolide results in decreased expression of FKBP11 mRNA CTD PMID:32835833 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO triptolide results in decreased expression of FKBP5 mRNA CTD PMID:32835833 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Fmn1 formin 1 decreases expression ISO triptolide results in decreased expression of FMN1 mRNA CTD PMID:32835833 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression EXP triptolide affects the expression of FMO5 protein CTD PMID:32519852 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fnip2 folliculin interacting protein 2 decreases expression ISO triptolide results in decreased expression of FNIP2 mRNA CTD PMID:32835833 NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901
JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO triptolide results in decreased phosphorylation of FOXO3 protein CTD PMID:32061799 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO triptolide results in decreased expression of FOXP3 mRNA CTD PMID:24949944 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO triptolide results in decreased expression of FRMD4B mRNA CTD PMID:32835833 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP triptolide results in increased expression of FTH1 protein CTD PMID:32519852 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP triptolide results in increased expression of FTL1 protein CTD PMID:32519852 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO triptolide results in increased expression of FUBP1 mRNA CTD PMID:32835833 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fundc2 FUN14 domain containing 2 decreases expression EXP triptolide results in decreased expression of FUNDC2 protein CTD PMID:32519852 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases expression
EXP Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression
multiple interactions
EXP
ISO
triptolide results in decreased expression of G6PC1 mRNA
triptolide results in decreased expression of G6PC mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of G6PC mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of G6PC mRNA]
CTD PMID:23639586 PMID:30633930 PMID:32835833 NCBI chr10:86,307,400...86,318,766 JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO triptolide results in increased expression of G6PDX mRNA CTD PMID:32835833 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gaa alpha glucosidase increases expression EXP triptolide results in increased expression of GAA protein CTD PMID:32519852 NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases expression ISO triptolide results in decreased expression of GABBR2 mRNA CTD PMID:32835833 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO triptolide results in increased expression of GADD45B mRNA CTD PMID:32835833 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP triptolide results in decreased expression of GADD45G mRNA CTD PMID:23639586 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO triptolide results in decreased expression of GAL3ST1 mRNA CTD PMID:32835833 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
JBrowse link
G Galk1 galactokinase 1 decreases expression ISO triptolide results in decreased expression of GALK1 mRNA CTD PMID:32835833 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337
JBrowse link
G Galm galactose mutarotase decreases expression EXP triptolide results in decreased expression of GALM mRNA CTD PMID:23639586 NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 increases expression EXP triptolide results in increased expression of GALNT11 protein CTD PMID:32519852 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140
JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 increases expression EXP triptolide results in increased expression of GALNT3 protein CTD PMID:32519852 NCBI chr 3:50,742,500...50,779,266
Ensembl chr 3:50,742,512...50,766,268
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP triptolide results in increased expression of GALNT7 protein CTD PMID:32519852 NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO triptolide results in decreased expression of GAMT mRNA CTD PMID:32835833 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO triptolide results in decreased expression of GAS1 mRNA CTD PMID:32835833 NCBI chr17:4,482,014...4,485,155 JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 increases expression ISO triptolide results in increased expression of GAS2L1 mRNA CTD PMID:32835833 NCBI chr14:79,951,702...79,961,830
Ensembl chr14:79,950,555...79,961,438
JBrowse link
G Gask1a golgi associated kinase 1A decreases expression ISO triptolide results in decreased expression of FAM198A mRNA CTD PMID:32835833 NCBI chr 8:121,610,779...121,643,742
Ensembl chr 8:121,610,787...121,642,942
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO triptolide results in decreased expression of GBE1 mRNA CTD PMID:32835833 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP triptolide results in increased expression of GBP2 protein CTD PMID:32519852 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gck glucokinase decreases expression EXP triptolide results in decreased expression of GCK mRNA CTD PMID:23639586 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
multiple interactions
ISO
EXP
triptolide results in decreased expression of GCLC protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of GCLC protein]
CTD PMID:25169008 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO triptolide results in increased expression of GDF9 mRNA CTD PMID:32835833 NCBI chr10:37,589,200...37,599,970
Ensembl chr10:37,595,679...37,599,672
JBrowse link
G Gimap4 GTPase, IMAP family member 4 increases expression EXP triptolide results in increased expression of GIMAP4 protein CTD PMID:32519852 NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions
ISO triptolide results in decreased expression of GJA1 mRNA; triptolide results in decreased expression of GJA1 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of GJA1 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of GJA1 protein]
CTD PMID:30836114 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression EXP triptolide results in decreased expression of GLMP protein CTD PMID:32519852 NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960
JBrowse link
G Gls glutaminase increases expression ISO triptolide results in increased expression of GLS mRNA CTD PMID:32835833 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase increases expression EXP triptolide results in increased expression of GMDS protein CTD PMID:32519852 NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO triptolide results in decreased expression of GNMT mRNA CTD PMID:32835833 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gon4l gon-4 like increases expression ISO triptolide results in increased expression of GON4L mRNA CTD PMID:32835833 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression ISO triptolide results in decreased expression of GOT1 mRNA CTD PMID:32835833 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gp5 glycoprotein V (platelet) increases expression ISO triptolide results in increased expression of GP5 mRNA CTD PMID:32835833 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 increases expression EXP triptolide results in increased expression of GPAA1 protein CTD PMID:32519852 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484
JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO triptolide results in increased expression of GPKOW mRNA CTD PMID:32835833 NCBI chr  X:14,791,601...14,806,384
Ensembl chr  X:14,791,610...14,806,384
JBrowse link
G Gpr12 G protein-coupled receptor 12 decreases expression ISO triptolide results in decreased expression of GPR12 mRNA CTD PMID:32835833 NCBI chr12:8,522,709...8,525,875
Ensembl chr12:8,522,953...8,527,973
JBrowse link
G Gpr146 G protein-coupled receptor 146 decreases expression ISO triptolide results in decreased expression of GPR146 mRNA CTD PMID:32835833 NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
increases expression
ISO
EXP
triptolide results in increased activity of GPT protein
[Atorvastatin co-treated with triptolide] results in increased expression of GPT protein
triptolide results in increased expression of GPT protein
catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]; catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [triptolide results in increased expression of GPT protein]; Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]
ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]
CTD PMID:23836259 PMID:26134275 PMID:30682494 PMID:32987112 PMID:33600922 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA]
triptolide results in increased expression of GPX1 protein
CTD PMID:31241159 PMID:32519852 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] CTD PMID:31241159 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] CTD PMID:31241159 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions
ISO triptolide results in increased expression of GPX4 mRNA
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA]
CTD PMID:31241159 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO triptolide results in decreased expression of GRB2 protein CTD PMID:26420756 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO triptolide results in decreased expression of GREM2 mRNA CTD PMID:32835833 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO triptolide results in increased expression of GRHL1 mRNA CTD PMID:32835833 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO triptolide results in increased expression of GRIK5 mRNA CTD PMID:32835833 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression ISO triptolide results in increased expression of GRWD1 mRNA CTD PMID:32835833 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
JBrowse link
G Gsdmd gasdermin D increases expression EXP triptolide results in increased expression of GSDMD protein CTD PMID:32519852 NCBI chr 7:107,542,242...107,547,052
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
EXP Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein] CTD PMID:30926361 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression ISO triptolide results in decreased expression of GSTA3 mRNA CTD PMID:32835833 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 increases expression ISO triptolide results in increased expression of GTF2F1 mRNA CTD PMID:32835833 NCBI chr 9:1,844,027...1,853,455
Ensembl chr 9:1,843,901...1,853,423
JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO triptolide results in increased expression of GTPBP4 mRNA CTD PMID:32835833 NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO triptolide results in increased expression of GTSE1 mRNA CTD PMID:32835833 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G Gusb glucuronidase, beta multiple interactions
decreases activity
ISO resveratrol inhibits the reaction [triptolide results in decreased activity of GUSB protein] CTD PMID:29723566 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G Gys2 glycogen synthase 2 decreases expression ISO triptolide results in decreased expression of GYS2 mRNA CTD PMID:32835833 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO triptolide results in increased expression of H1F4 mRNA CTD PMID:32835833 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H2ax H2A.X variant histone increases expression ISO triptolide results in increased expression of H2AX mRNA CTD PMID:32835833 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bu1 H2B.U histone 1 increases expression ISO triptolide results in increased expression of H2BC21 mRNA; triptolide results in increased expression of H2BC6 mRNA CTD PMID:32835833 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277
JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO triptolide results in increased expression of H4C3 mRNA CTD PMID:32835833
G H4f16 H4 histone 16 increases expression ISO triptolide results in increased expression of H4F16 mRNA CTD PMID:32835833
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO triptolide results in decreased expression of HAAO mRNA CTD PMID:32835833 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877
JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression ISO triptolide results in decreased expression of HAO1 mRNA CTD PMID:32835833 NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression EXP triptolide results in increased expression of HBA-A2 protein; triptolide results in increased expression of HBA1 protein CTD PMID:32519852 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP triptolide results in increased expression of HBB protein CTD PMID:32519852 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hdac1 histone deacetylase 1 increases expression EXP triptolide results in increased expression of HDAC1 mRNA CTD PMID:23639586 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac1l histone deacetylase 1-like increases expression EXP triptolide results in increased expression of HDAC1L protein CTD PMID:32519852 NCBI chr 9:80,453,139...80,454,593
Ensembl chr 9:80,453,139...80,454,593
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP triptolide results in increased expression of HDAC2 protein CTD PMID:32519852 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac6 histone deacetylase 6 increases expression ISO triptolide results in increased expression of HDAC6 mRNA; triptolide results in increased expression of HDAC6 protein CTD PMID:32061799 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 increases expression EXP triptolide results in increased expression of HERC6 protein CTD PMID:32519852 NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO triptolide results in decreased expression of HERPUD1 mRNA CTD PMID:32835833 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
increases expression
multiple interactions
ISO triptolide results in decreased expression of HES1 protein
triptolide results in increased expression of HES1 mRNA
triptolide results in decreased expression of HES1 mRNA; triptolide results in decreased expression of HES1 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of HES1 protein]
CTD PMID:30394310 PMID:31241159 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO triptolide results in decreased expression of HES6 mRNA CTD PMID:32835833 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO triptolide results in increased expression of HEXIM1 mRNA CTD PMID:32835833 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Higd2al1 HIG1 hypoxia inducible domain family, member 2A-like 1 increases expression EXP triptolide results in increased expression of HIGD2AL1 protein CTD PMID:32519852 NCBI chr12:2,777,094...2,777,581
Ensembl chr12:2,777,231...2,777,551
JBrowse link
G Hikeshi heat shock protein nuclear import factor increases expression EXP triptolide results in increased expression of HIKESHI protein CTD PMID:32519852 NCBI chr 1:143,825,922...143,849,374
Ensembl chr 1:143,825,923...143,849,363
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO triptolide results in increased expression of H3C6 mRNA CTD PMID:32835833 NCBI chr17:41,568,666...41,569,076
Ensembl chr17:41,568,471...41,569,109
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 increases expression ISO triptolide results in increased expression of H3C11 mRNA CTD PMID:32835833 NCBI chr 2:183,837,311...183,837,721
Ensembl chr 2:183,837,303...183,837,752
JBrowse link
G Hist2h4 histone cluster 2, H4 increases expression ISO triptolide results in increased expression of H4C11 mRNA CTD PMID:32835833 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A increases expression ISO triptolide results in increased expression of H4C8 mRNA CTD PMID:32835833
G Hist3h2a histone cluster 3, H2a increases expression ISO triptolide results in increased expression of H2AC6 mRNA CTD PMID:32835833 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HMGCR mRNA CTD PMID:31557376 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO triptolide results in decreased expression of HMGCS1 mRNA CTD PMID:32835833 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
affects expression
decreases expression
EXP
ISO
triptolide results in increased expression of HMOX1 mRNA
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of HMOX1 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]
[triptolide co-treated with catalpol co-treated with Saponins] results in increased expression of HMOX1 protein; [triptolide co-treated with catalpol] results in increased expression of HMOX1 protein; [triptolide co-treated with Saponins] results in increased expression of HMOX1 protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]
triptolide affects the expression of HMOX1 mRNA
triptolide results in decreased expression of HMOX1 mRNA; triptolide results in decreased expression of HMOX1 protein
CTD PMID:23639586 PMID:25169008 PMID:30682494 PMID:30836114 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of HNMT mRNA CTD PMID:32835833 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hp haptoglobin increases expression EXP triptolide results in increased expression of HP protein CTD PMID:32519852 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase decreases expression ISO triptolide results in decreased expression of HPD mRNA CTD PMID:32835833 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
JBrowse link
G Hpx hemopexin increases expression EXP triptolide results in increased expression of HPX protein CTD PMID:32519852 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression EXP triptolide results in decreased expression of HRAS mRNA CTD PMID:23639586 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Hrg histidine-rich glycoprotein increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of HRG protein
triptolide results in decreased expression of HRG mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HSD3B2 mRNA CTD PMID:31557376 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein increases expression ISO triptolide results in increased expression of HSF2BP mRNA CTD PMID:32835833 NCBI chr20:10,035,562...10,123,059
Ensembl chr20:10,035,562...10,121,242
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO triptolide results in increased expression of HSP90AA1 mRNA CTD PMID:32835833 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases response to substance ISO HSPA1A results in decreased susceptibility to triptolide CTD PMID:19546256
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP triptolide results in increased expression of HSPA1B protein CTD PMID:32519852 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP triptolide results in increased expression of HSPA2 protein CTD PMID:32519852 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like affects expression ISO triptolide affects the expression of HSPA4L mRNA CTD PMID:32835833 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO triptolide results in decreased expression of HSPA5 protein CTD PMID:26990902 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP triptolide results in decreased expression of HSPD1 protein CTD PMID:32519852 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression ISO triptolide results in decreased expression of HTRA4 mRNA CTD PMID:32835833 NCBI chr16:67,001,605...67,015,074
Ensembl chr16:67,001,605...67,015,074
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
increases expression
multiple interactions
ISO triptolide results in decreased expression of ICAM1 mRNA; triptolide results in decreased expression of ICAM1 protein
triptolide results in increased expression of ICAM1 mRNA; triptolide results in increased expression of ICAM1 protein
TRAJ18 protein affects the reaction [triptolide results in increased expression of ICAM1 protein]
CTD PMID:17931847 PMID:32835833 PMID:32987112 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO triptolide results in decreased expression of IDI1 mRNA CTD PMID:32835833 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Idua alpha-L-iduronidase increases expression ISO triptolide results in increased expression of IDUA mRNA CTD PMID:32835833 NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522
JBrowse link
G Ier5 immediate early response 5 increases expression ISO triptolide results in increased expression of IER5 mRNA CTD PMID:32835833 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Ifit1bl interferon-induced protein with tetratricopeptide repeats 1B-like increases expression EXP triptolide results in increased expression of IFIT1 protein CTD PMID:32519852 NCBI chr 1:232,122,618...232,167,329
Ensembl chr 1:232,122,562...232,167,518
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP triptolide results in increased expression of IFIT2 protein CTD PMID:32519852 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression EXP triptolide results in increased expression of IFIT3 protein CTD PMID:32519852 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifng interferon gamma multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:15663903 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 increases expression EXP triptolide results in increased expression of IGDCC3 protein CTD PMID:32519852 NCBI chr 8:65,661,165...65,707,961
Ensembl chr 8:65,661,196...65,707,959
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO triptolide results in decreased expression of IGF1 mRNA CTD PMID:32835833 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression ISO triptolide results in decreased expression of IGF2BP3 mRNA CTD PMID:32835833 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression EXP
ISO
triptolide results in decreased expression of IGFBP1 mRNA CTD PMID:23639586 PMID:32835833 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO triptolide results in decreased expression of IGFBP4 mRNA CTD PMID:32835833 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G IgG-2a gamma-2a immunoglobulin heavy chain increases expression EXP triptolide results in increased expression of IGG-2A protein CTD PMID:32519852
G Ighe immunoglobulin heavy constant epsilon increases expression EXP triptolide results in increased expression of IGHM protein CTD PMID:32519852
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
decreases phosphorylation
ISO
EXP
TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of IKBKB protein]
pifithrin inhibits the reaction [triptolide results in decreased phosphorylation of IKBKB protein]
CTD PMID:31618665 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il12a interleukin 12A multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15663903 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein] CTD PMID:15663903 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
ISO IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]
triptolide results in increased expression of IL17A mRNA; triptolide results in increased expression of IL17A protein
CTD PMID:24949944 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il18 interleukin 18 decreases expression ISO triptolide results in decreased expression of IL18 mRNA CTD PMID:32835833 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:24949944 PMID:30633930 PMID:31241159 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 increases secretion ISO triptolide results in increased secretion of IL4 protein CTD PMID:32987112 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:30633930 PMID:31241159 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression ISO triptolide results in increased expression of IMP4 mRNA CTD PMID:32835833 NCBI chr 9:36,654,127...36,659,265
Ensembl chr 9:36,654,401...36,660,075
JBrowse link
G Impa2 inositol monophosphatase 2 decreases expression ISO triptolide results in decreased expression of IMPA2 mRNA CTD PMID:32835833 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO triptolide results in increased expression of IMPDH2 mRNA CTD PMID:32835833 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359
JBrowse link
G Inava innate immunity activator increases expression ISO triptolide results in increased expression of INAVA mRNA CTD PMID:32835833 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 affects expression ISO triptolide affects the expression of INCA1 mRNA CTD PMID:32835833 NCBI chr10:55,401,982...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO triptolide results in increased expression of FAM212B mRNA CTD PMID:32835833 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of INMT mRNA CTD PMID:32835833 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Insc INSC, spindle orientation adaptor protein affects expression ISO triptolide affects the expression of INSC mRNA CTD PMID:32835833 NCBI chr 1:168,993,032...169,100,438
Ensembl chr 1:168,993,032...169,100,433
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO triptolide results in decreased expression of INSIG1 mRNA CTD PMID:32835833 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insr insulin receptor increases expression EXP triptolide results in increased expression of INSR protein CTD PMID:32519852 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Ints2 integrator complex subunit 2 increases expression ISO triptolide results in increased expression of INTS2 mRNA CTD PMID:32835833 NCBI chr10:71,031,647...71,079,138
Ensembl chr10:71,031,647...71,079,076
JBrowse link
G Ipo13 importin 13 increases expression ISO triptolide results in increased expression of IPO13 mRNA CTD PMID:32835833 NCBI chr 5:131,433,770...131,454,044
Ensembl chr 5:131,433,776...131,454,043
JBrowse link
G Irgm immunity-related GTPase M increases expression EXP triptolide results in increased expression of IRGM protein CTD PMID:32519852 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578
JBrowse link
G Irs1 insulin receptor substrate 1 increases degradation
multiple interactions
ISO triptolide results in increased degradation of IRS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein]; triptolide results in decreased expression of and results in decreased phosphorylation of IRS1 protein
CTD PMID:32061799 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression EXP triptolide results in decreased expression of ISCA1 protein CTD PMID:32519852 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme decreases expression EXP triptolide results in decreased expression of ISCU protein CTD PMID:32519852 NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP triptolide results in increased expression of ISYNA1 protein CTD PMID:32519852 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP
ISO
triptolide results in increased expression of ITGA5 protein
triptolide results in increased expression of ITGA5 mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP triptolide results in increased expression of ITIH3 protein CTD PMID:32519852 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression EXP triptolide results in increased expression of ITIH4 protein CTD PMID:32519852 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression EXP triptolide results in increased expression of ITPR3 protein CTD PMID:32519852 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
JBrowse link
G Jph1 junctophilin 1 decreases expression ISO triptolide results in decreased expression of JPH1 mRNA CTD PMID:32835833 NCBI chr 5:2,030,227...2,137,171
Ensembl chr 5:2,030,281...2,125,284
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression ISO triptolide results in increased expression of HN1 mRNA CTD PMID:32835833 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO triptolide results in increased expression of JUN mRNA CTD PMID:32835833 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kctd18 potassium channel tetramerization domain containing 18 increases expression ISO triptolide results in increased expression of KCTD18 mRNA CTD PMID:32835833 NCBI chr 9:59,502,220...59,566,857
Ensembl chr 9:59,502,232...59,566,857
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO triptolide results in decreased expression of KEAP1 protein CTD PMID:30682494 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khsrp KH-type splicing regulatory protein decreases expression EXP triptolide results in decreased expression of KHSRP protein CTD PMID:32519852 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO triptolide results in increased expression of KIF20A mRNA CTD PMID:32835833 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif21a kinesin family member 21A increases expression EXP triptolide results in increased expression of KIF21A protein CTD PMID:32519852 NCBI chr 7:122,062,523...122,179,051
Ensembl chr 7:122,062,537...122,178,999
JBrowse link
G Kifc3 kinesin family member C3 increases expression ISO triptolide results in increased expression of KIFC3 mRNA CTD PMID:32835833 NCBI chr19:9,825,208...9,920,371
Ensembl chr19:9,886,693...9,920,451
JBrowse link
G Klc1 kinesin light chain 1 increases expression ISO triptolide results in increased expression of KLC1 mRNA CTD PMID:32835833 NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031
JBrowse link
G Klhl26 kelch-like family member 26 increases expression ISO triptolide results in increased expression of KLHL26 mRNA CTD PMID:32835833 NCBI chr16:18,952,123...18,977,328
Ensembl chr16:18,952,234...18,977,328
JBrowse link
G Klkb1 kallikrein B1 decreases expression ISO triptolide results in decreased expression of KLKB1 mRNA CTD PMID:32835833 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
JBrowse link
G Kng2 kininogen 2 increases expression EXP triptolide results in increased expression of KNG1 protein; triptolide results in increased expression of MAP1 protein CTD PMID:32519852 NCBI chr11:77,913,876...77,936,247 JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP triptolide results in increased expression of KRAS mRNA CTD PMID:23639586 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO triptolide results in decreased expression of KYAT1 mRNA CTD PMID:32835833 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
JBrowse link
G Kyat3 kynurenine aminotransferase 3 decreases expression ISO triptolide results in decreased expression of KYAT3 mRNA CTD PMID:32835833 NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227
JBrowse link
G L1cam L1 cell adhesion molecule increases expression EXP triptolide results in increased expression of L1CAM protein CTD PMID:32519852 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857
JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 decreases expression EXP triptolide results in decreased expression of LAMTOR1 protein CTD PMID:32519852 NCBI chr 1:156,272,116...156,277,687
Ensembl chr 1:156,272,064...156,291,179
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO triptolide results in increased expression of LCAT mRNA CTD PMID:32835833 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Ldb3 LIM domain binding 3 increases expression ISO triptolide results in increased expression of LDB3 mRNA CTD PMID:32835833 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532
JBrowse link
G Lepr leptin receptor decreases expression ISO triptolide results in decreased expression of LEPR mRNA CTD PMID:32835833 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Letmd1 LETM1 domain containing 1 increases expression EXP triptolide results in increased expression of LETMD1 protein CTD PMID:32519852 NCBI chr 7:131,584,241...131,597,797
Ensembl chr 7:131,584,259...131,597,796
JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO triptolide results in increased expression of LGI4 mRNA CTD PMID:32835833 NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO triptolide results in decreased expression of LIPG mRNA CTD PMID:32835833 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO triptolide results in increased expression of LITAF mRNA CTD PMID:32835833 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lmna lamin A/C increases expression ISO triptolide results in increased expression of LMNA mRNA CTD PMID:32835833 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G LOC100909593 class II histocompatibility antigen, M alpha chain-like increases expression ISO triptolide results in increased expression of H2-DMA mRNA CTD PMID:32835833
G LOC100912290 histone H4-like increases expression ISO triptolide results in increased expression of H4C4 mRNA CTD PMID:32835833
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO triptolide results in increased expression of LONRF3 mRNA CTD PMID:32835833 NCBI chr  X:115,565,214...115,603,886
Ensembl chr  X:115,565,267...115,598,809
JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression ISO triptolide results in increased expression of LOXL4 mRNA CTD PMID:32835833 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
JBrowse link
G Lpin1 lipin 1 decreases expression ISO triptolide results in decreased expression of LPIN1 mRNA CTD PMID:32835833 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lpxn leupaxin increases expression ISO triptolide results in increased expression of LPXN mRNA CTD PMID:32835833 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
JBrowse link
G Lrrc14 leucine rich repeat containing 14 increases expression ISO triptolide results in increased expression of LRRC14 mRNA CTD PMID:32835833 NCBI chr 7:108,430,779...108,437,118
Ensembl chr 7:108,430,792...108,437,111
JBrowse link
G Lrrc51 leucine rich repeat containing 51 increases expression ISO triptolide results in increased expression of LRRC51 mRNA CTD PMID:32835833 NCBI chr 1:156,278,617...156,297,838
Ensembl chr 1:156,278,618...156,297,773
JBrowse link
G Lrrn4cl LRRN4 C-terminal like increases expression ISO triptolide results in increased expression of LRRN4CL mRNA CTD PMID:32835833 NCBI chr 1:205,743,580...205,759,879 JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 decreases expression ISO triptolide results in decreased expression of LRTM1 mRNA CTD PMID:32835833 NCBI chr16:4,210,343...4,217,843 JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 increases expression ISO triptolide results in increased expression of ORAOV1 mRNA CTD PMID:32835833 NCBI chr 1:200,074,247...200,080,951
Ensembl chr 1:200,074,253...200,088,061
JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression EXP triptolide results in increased expression of LY6E protein CTD PMID:32519852 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Mab21l3 mab-21 like 3 increases expression ISO triptolide results in increased expression of MAB21L3 mRNA CTD PMID:32835833 NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression EXP triptolide results in increased expression of MAD2L1 mRNA CTD PMID:23639586 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression ISO triptolide results in decreased expression of MAFB mRNA CTD PMID:32835833 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO triptolide affects the expression of MAFF mRNA CTD PMID:32835833 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO triptolide results in increased expression of MAP1S mRNA CTD PMID:32835833 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO triptolide results in decreased expression of MAP2K6 mRNA CTD PMID:32835833 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
JBrowse link
G Map7d1 MAP7 domain containing 1 increases expression ISO triptolide results in increased expression of MAP7D1 mRNA CTD PMID:32835833 NCBI chr 5:138,527,944...138,552,537
Ensembl chr 5:138,527,401...138,552,499
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21717513 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] CTD PMID:17507666 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21717513 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO triptolide results in increased expression of MAPK8IP3 mRNA CTD PMID:32835833 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273
JBrowse link
G Mast3 microtubule associated serine/threonine kinase 3 increases expression EXP triptolide results in increased expression of MAST3 protein CTD PMID:32519852 NCBI chr16:18,636,764...18,663,852
Ensembl chr16:18,636,787...18,663,852
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 increases expression EXP triptolide results in increased expression of MBNL1 protein CTD PMID:32519852 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368
JBrowse link
G Mcee methylmalonyl CoA epimerase increases expression EXP triptolide results in increased expression of MCEE protein CTD PMID:32519852 NCBI chr 1:117,964,576...117,987,779
Ensembl chr 1:117,964,576...117,988,484
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO triptolide results in increased expression of MCL1 protein CTD PMID:26990902 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP triptolide results in increased expression of MCM6 mRNA CTD PMID:23639586 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 increases expression ISO triptolide results in increased expression of MCRIP1 mRNA CTD PMID:32835833 NCBI chr10:105,820,656...105,828,146
Ensembl chr10:105,820,656...105,828,271
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO triptolide results in increased expression of MDM2 mRNA CTD PMID:32835833 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO triptolide results in decreased expression of ME1 mRNA CTD PMID:32835833 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med23 mediator complex subunit 23 increases expression EXP triptolide results in increased expression of MED23 protein CTD PMID:32519852 NCBI chr 1:20,490,315...20,558,461
Ensembl chr 1:20,490,315...20,537,463
JBrowse link
G Mep1a meprin A subunit alpha increases expression EXP triptolide results in increased expression of MEP1A protein CTD PMID:32519852 NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147
JBrowse link
G Mep1b meprin A subunit beta increases expression EXP triptolide results in increased expression of MEP1B protein CTD PMID:32519852 NCBI chr18:12,366,126...12,392,840
Ensembl chr18:12,365,289...12,392,840
JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions
ISO triptolide results in decreased expression of MFN2 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of MFN2 protein]
CTD PMID:30836114 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression ISO triptolide results in decreased expression of MFSD2A mRNA CTD PMID:32835833 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Mfsd4b major facilitator superfamily domain containing 4B decreases expression ISO triptolide results in decreased expression of MFSD4B1 mRNA CTD PMID:32835833 NCBI chr20:43,324,429...43,333,914
Ensembl chr20:43,324,436...43,333,953
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 increases expression ISO triptolide results in increased expression of MICAL2 mRNA CTD PMID:32835833 NCBI chr 1:166,345,853...166,471,715
NCBI chr 1:166,491,721...166,530,575
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 increases expression ISO triptolide results in increased expression of MICAL3 mRNA CTD PMID:32835833 NCBI chr 4:154,152,776...154,353,274
Ensembl chr 4:154,153,834...154,302,590
JBrowse link
G Mir141 microRNA 141 multiple interactions ISO [triptolide co-treated with tariquidar] results in increased activity of MIR141 protein CTD PMID:26134275 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO triptolide results in decreased expression of MKI67 protein CTD PMID:24842335 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression
ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein; [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form]; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein]
triptolide results in increased expression of MLKL mRNA
CTD PMID:30633930 PMID:32835833 NCBI chr19:39,278,123...39,304,555
Ensembl chr19:39,276,785...39,304,502
JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 decreases expression ISO triptolide results in decreased expression of MMD2 mRNA CTD PMID:32835833 NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
JBrowse link
G Mme membrane metallo-endopeptidase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of MME protein
triptolide results in decreased expression of MME mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO triptolide results in increased expression of MMP12 mRNA CTD PMID:32835833 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO triptolide results in decreased expression of MMP2 mRNA; triptolide results in decreased expression of MMP2 protein CTD PMID:26420756 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO triptolide results in decreased expression of MMP9 protein
triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein]
CTD PMID:25200491 PMID:26420756 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 increases expression ISO triptolide results in increased expression of MOGAT2 mRNA CTD PMID:32835833 NCBI chr 1:153,521,813...153,545,756
Ensembl chr 1:153,521,815...153,545,756
JBrowse link
G Mov10 Mov10 RISC complex RNA helicase decreases expression ISO triptolide results in decreased expression of MOV10 mRNA CTD PMID:32835833 NCBI chr 2:192,292,041...192,315,142
Ensembl chr 2:192,293,470...192,315,083
JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression EXP triptolide results in decreased expression of MPC1 protein CTD PMID:32519852 NCBI chr 1:52,437,745...52,449,369
Ensembl chr 1:52,437,741...52,449,400
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO triptolide promotes the reaction [Lipopolysaccharides results in increased expression of MPO mRNA] CTD PMID:30633930 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 increases expression ISO triptolide results in increased expression of MPP7 mRNA CTD PMID:32835833 NCBI chr17:55,439,939...55,706,810
Ensembl chr17:55,442,696...55,706,748
JBrowse link
G Mreg melanoregulin increases expression ISO triptolide results in increased expression of MREG mRNA CTD PMID:32835833 NCBI chr 9:73,786,727...73,842,081
Ensembl chr 9:73,787,267...73,842,087
JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 increases expression EXP triptolide results in increased expression of MRPS5 protein CTD PMID:32519852 NCBI chr 3:114,821,046...114,837,291
Ensembl chr 3:114,821,046...114,837,291
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO triptolide results in decreased expression of MSMO1 mRNA CTD PMID:32835833 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression EXP triptolide results in increased expression of ND1 protein CTD PMID:32519852 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt1 metallothionein 1 decreases expression
increases expression
EXP triptolide results in decreased expression of MT1 protein
triptolide results in increased expression of MT1M protein
CTD PMID:32519852 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mtdh metadherin increases expression ISO triptolide results in increased expression of MTDH mRNA CTD PMID:32835833 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO triptolide results in increased expression of and results in increased phosphorylation of MTOR protein CTD PMID:26990902 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP triptolide results in increased expression of MUG1 protein CTD PMID:32519852 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Mug2 murinoglobulin 2 decreases expression ISO triptolide results in decreased expression of MUG2 mRNA CTD PMID:32835833 NCBI chr 4:155,164,061...155,236,765
Ensembl chr 4:155,164,011...155,236,475
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression
decreases expression
EXP
ISO
triptolide results in increased expression of MVD protein
triptolide results in decreased expression of MVD mRNA
CTD PMID:32519852 PMID:32835833 NCBI chr19:50,496,366...50,506,389
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression EXP triptolide results in increased expression of MX1 protein CTD PMID:32519852 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO triptolide results in increased expression of MYBL1 mRNA CTD PMID:32835833 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression ISO triptolide results in increased expression of MYBL2 mRNA CTD PMID:32835833 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression
EXP
ISO
triptolide results in decreased expression of MYC mRNA
triptolide results in increased expression of MYC mRNA
triptolide results in decreased expression of MYC protein
CTD PMID:12533674 PMID:23639586 PMID:32835833 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycbpap Mycbp associated protein increases expression ISO triptolide results in increased expression of MYCBPAP mRNA CTD PMID:32835833 NCBI chr10:79,450,319...79,470,977
Ensembl chr10:79,450,324...79,470,828
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO triptolide results in decreased expression of MYCL mRNA CTD PMID:32835833 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Myh1 myosin heavy chain 1 decreases expression ISO triptolide results in decreased expression of MYH1 mRNA CTD PMID:32061799 NCBI chr10:51,885,913...51,909,699 JBrowse link
G Myh2 myosin heavy chain 2 decreases expression ISO triptolide results in decreased expression of MYH2 mRNA CTD PMID:32061799 NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236
JBrowse link
G Myh4 myosin heavy chain 4 decreases expression ISO triptolide results in decreased expression of MYH4 mRNA CTD PMID:32061799 NCBI chr10:51,923,149...51,946,297 JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO triptolide results in decreased expression of MYH7 mRNA CTD PMID:32061799 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myh7b myosin heavy chain 7B increases expression ISO triptolide results in increased expression of MYH7B mRNA CTD PMID:32835833 NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Myl9 myosin light chain 9 decreases expression EXP triptolide results in decreased expression of MYL9 protein CTD PMID:32519852 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Myo19 myosin XIX increases expression ISO triptolide results in increased expression of MYO19 mRNA CTD PMID:32835833 NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450
JBrowse link
G Myo5c myosin VC increases expression EXP triptolide results in increased expression of MYO5C protein CTD PMID:32519852 NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
JBrowse link
G Myom1 myomesin 1 increases expression ISO triptolide results in increased expression of MYOM1 mRNA CTD PMID:32835833 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
JBrowse link
G Myrfl myelin regulatory factor-like increases expression ISO triptolide results in increased expression of MYRFL mRNA CTD PMID:32835833 NCBI chr 7:52,403,324...52,519,907
Ensembl chr 7:52,403,650...52,519,907
JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression ISO triptolide results in decreased expression of NAALADL2 mRNA CTD PMID:32835833 NCBI chr 2:106,639,146...107,992,218 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO triptolide results in decreased expression of NAMPT mRNA CTD PMID:29723566 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
JBrowse link
G Nat8f4 N-acetyltransferase 8 (GCN5-related) family member 4 increases expression ISO triptolide results in increased expression of NAT8F4 mRNA CTD PMID:32835833 NCBI chr 4:118,326,092...118,332,591 JBrowse link
G Nat8f5 N-acetyltransferase 8 (GCN5-related) family member 5 affects expression ISO triptolide affects the expression of NAT8F5 mRNA CTD PMID:32835833 NCBI chr 4:118,260,323...118,285,038
Ensembl chr 4:118,260,252...118,285,704
JBrowse link
G Nbeal2 neurobeachin-like 2 increases expression ISO triptolide results in increased expression of NBEAL2 mRNA CTD PMID:32835833 NCBI chr 8:110,603,220...110,633,612
Ensembl chr 8:110,599,389...110,633,707
JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 increases expression ISO triptolide results in increased expression of NCBP1 mRNA CTD PMID:32835833 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 increases expression EXP triptolide results in increased expression of NCOA6 protein CTD PMID:32519852 NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 increases expression ISO triptolide results in increased expression of NCOR2 mRNA CTD PMID:32835833 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 increases expression ISO triptolide results in increased expression of NDOR1 mRNA CTD PMID:32835833 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP triptolide results in increased expression of NDUFA7 protein CTD PMID:32519852 NCBI chr 7:14,609,283...14,622,064 JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 increases expression EXP triptolide results in increased expression of NDUFB9 protein CTD PMID:32519852 NCBI chr 7:90,481,013...90,487,360 JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 increases expression EXP triptolide results in increased expression of NDUFS4 protein CTD PMID:32519852 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO triptolide results in decreased expression of NDUFS8 mRNA CTD PMID:29723566 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP triptolide results in increased expression of NDUFV3 protein CTD PMID:32519852 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
JBrowse link
G Necap1 NECAP endocytosis associated 1 decreases expression EXP triptolide results in decreased expression of NECAP1 protein CTD PMID:32519852 NCBI chr 4:156,103,935...156,119,068
Ensembl chr 4:156,103,988...156,119,068
JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO triptolide results in increased expression of NETO2 mRNA CTD PMID:32835833 NCBI chr19:21,344,299...21,418,182
Ensembl chr19:21,344,289...21,417,023
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
decreases expression
decreases phosphorylation
affects localization
affects expression
decreases response to substance
EXP
ISO
Acetylcysteine inhibits the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in increased ubiquitination of NFE2L2 protein]; Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of GCLC protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of NQO1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased expression of BAX protein]; triptolide affects the expression of and results in increased ubiquitination of NFE2L2 protein
triptolide results in increased expression of NFE2L2 mRNA; triptolide results in increased expression of NFE2L2 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of and affects the localization of NFE2L2 protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein]; triptolide results in decreased expression of and affects the localization of NFE2L2 protein
triptolide results in decreased expression of NFE2L2 mRNA
[catalpol co-treated with Saponins co-treated with triptolide] affects the localization of NFE2L2 protein; [catalpol co-treated with triptolide] affects the localization of NFE2L2 protein; [Saponins co-treated with triptolide] affects the localization of NFE2L2 protein; [triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein; [triptolide co-treated with Saponins] results in increased expression of NFE2L2 protein; catalpol inhibits the reaction [Saponins inhibits the reaction [triptolide results in decreased phosphorylation of NFE2L2 protein]]; catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [triptolide results in increased expression of GPT protein]; Saponins inhibits the reaction [triptolide results in decreased phosphorylation of NFE2L2 protein]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]]
triptolide affects the localization of NFE2L2 protein
triptolide affects the expression of NFE2L2 mRNA; triptolide affects the expression of NFE2L2 protein
triptolide results in decreased expression of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to triptolide
CTD PMID:22820427 PMID:25169008 PMID:30682494 PMID:30836114 PMID:30926361 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation
ISO
EXP
TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of NFKBIA protein] CTD PMID:31618665 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO triptolide results in increased expression of NFKBIE mRNA CTD PMID:32835833 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437
JBrowse link
G Ngf nerve growth factor increases expression
increases secretion
EXP triptolide results in increased expression of NGF mRNA; triptolide results in increased expression of NGF protein
triptolide results in increased secretion of NGF protein
CTD PMID:17401680 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO triptolide results in increased expression of TNFRSF10B mRNA; triptolide results in increased expression of TNFRSF10B protein CTD PMID:26990902 PMID:32835833 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression EXP triptolide results in increased expression of FAM129A protein CTD PMID:32519852 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 increases expression ISO triptolide results in increased expression of NIFK mRNA CTD PMID:32835833 NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896
JBrowse link
G Nipal1 NIPA-like domain containing 1 decreases expression ISO triptolide results in decreased expression of NIPAL1 mRNA CTD PMID:32835833 NCBI chr14:35,537,641...35,561,651
Ensembl chr14:35,540,324...35,561,659
JBrowse link
G Nle1 notchless homolog 1 increases expression ISO triptolide results in increased expression of NLE1 mRNA CTD PMID:32835833 NCBI chr10:67,834,059...67,844,771
Ensembl chr10:67,834,062...67,842,658
JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO triptolide results in decreased expression of NNMT mRNA CTD PMID:32835833 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression EXP triptolide results in increased expression of NNT protein CTD PMID:32519852 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO triptolide results in increased expression of NOC2L mRNA CTD PMID:32835833 NCBI chr 5:166,820,075...166,831,951
Ensembl chr 5:166,820,161...166,831,949
JBrowse link
G Nol6 nucleolar protein 6 increases expression ISO triptolide results in increased expression of NOL6 mRNA CTD PMID:32835833 NCBI chr 5:56,259,919...56,270,540
Ensembl chr 5:56,260,830...56,270,336
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 increases expression ISO triptolide results in increased expression of NOLC1 mRNA CTD PMID:32835833 NCBI chr 1:244,921,275...244,932,089
Ensembl chr 1:244,921,377...244,932,088
JBrowse link
G Nop2 NOP2 nucleolar protein increases expression ISO triptolide results in increased expression of NOP2 mRNA CTD PMID:32835833 NCBI chr 4:157,932,731...157,944,462
Ensembl chr 4:157,932,716...157,944,459
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO triptolide results in increased expression of NOP56 mRNA CTD PMID:32835833 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression ISO triptolide results in increased expression of NOP58 mRNA CTD PMID:32835833 NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810
JBrowse link
G Nop9 NOP9 nucleolar protein increases expression ISO triptolide results in increased expression of NOP9 mRNA CTD PMID:32835833 NCBI chr15:29,243,853...29,252,220
Ensembl chr15:29,243,862...29,252,220
JBrowse link
G Notch1 notch receptor 1 multiple interactions
increases expression
decreases expression
ISO NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]
triptolide results in increased expression of NOTCH1 mRNA
triptolide results in decreased expression of NOTCH1 mRNA; triptolide results in decreased expression of NOTCH1 protein; triptolide results in decreased expression of NOTCH1 protein modified form
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of HES1 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of CASP3 protein modified form]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of PTEN protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of TXNIP protein]
CTD PMID:30394310 PMID:31241159 PMID:32835833 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notch3 notch receptor 3 increases expression
multiple interactions
ISO triptolide results in increased expression of NOTCH3 mRNA; triptolide results in increased expression of NOTCH3 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein]
CTD PMID:31241159 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
JBrowse link
G Nox4 NADPH oxidase 4 decreases expression ISO triptolide results in decreased expression of NOX4 mRNA CTD PMID:32835833 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions ISO
EXP
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein] CTD PMID:18509322 NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO
EXP
triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein] CTD PMID:18509322 NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
JBrowse link
G Npm2 nucleophosmin/nucleoplasmin 2 increases expression ISO triptolide results in increased expression of NPM2 mRNA CTD PMID:32835833 NCBI chr15:45,722,494...45,729,246
Ensembl chr15:45,722,400...45,729,726
JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit increases expression ISO triptolide results in increased expression of NPRL3 mRNA CTD PMID:32835833 NCBI chr10:15,355,361...15,395,812
Ensembl chr10:15,355,355...15,395,810
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
increases expression
multiple interactions
ISO
EXP
triptolide results in decreased expression of NQO1 mRNA; triptolide results in decreased expression of NQO1 protein
triptolide results in increased expression of NQO1 protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of NQO1 mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of NQO1 protein]
[triptolide co-treated with catalpol] results in increased expression of NQO1 protein; [triptolide co-treated with Saponins] results in increased expression of NQO1 protein; catalpol promotes the reaction [[triptolide co-treated with Saponins] results in increased expression of NQO1 protein]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NQO1 protein]
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of NQO1 protein]
CTD PMID:25169008 PMID:30682494 PMID:30836114 PMID:32519852 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions
ISO triptolide results in decreased expression of NR0B2 mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of NR0B2 mRNA]
CTD PMID:30633930 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO triptolide results in decreased expression of NR1D1 mRNA CTD PMID:32835833 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression ISO triptolide results in decreased expression of NR1D2 mRNA CTD PMID:32835833 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions
ISO triptolide results in decreased expression of NR1H4 mRNA; triptolide results in decreased expression of NR1H4 protein
[triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR1H4 protein; Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of NR1H4 mRNA]; TRAJ18 protein affects the reaction [triptolide results in decreased expression of NR1H4 protein]
CTD PMID:30633930 PMID:32987112 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
decreases expression
increases expression
ISO
EXP
triptolide results in increased expression of and results in increased phosphorylation of NR3C1 protein
triptolide results in decreased expression of NR3C1 mRNA
triptolide results in increased expression of NR3C1 mRNA
CTD PMID:19330649 PMID:23639586 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nrf1 nuclear respiratory factor 1 decreases expression ISO triptolide results in decreased expression of NRF1 mRNA CTD PMID:29723566 NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
JBrowse link
G Nrg4 neuregulin 4 decreases expression ISO triptolide results in decreased expression of NRG4 mRNA CTD PMID:32835833 NCBI chr 8:55,586,253...55,677,829
Ensembl chr 8:55,592,893...55,677,483
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO triptolide results in increased expression of NRIP1 mRNA CTD PMID:32835833 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO triptolide results in decreased expression of NSDHL mRNA CTD PMID:32835833 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 increases expression ISO triptolide results in increased expression of NSUN3 mRNA CTD PMID:32835833 NCBI chr11:37,490,832...37,575,607 JBrowse link
G Nt5c 5', 3'-nucleotidase, cytosolic increases expression EXP triptolide results in increased expression of NT5C protein CTD PMID:32519852 NCBI chr10:100,739,591...100,742,276
Ensembl chr10:100,739,588...100,741,954
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression EXP triptolide results in decreased expression of NTRK1 mRNA CTD PMID:23639586 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Nubp2 nucleotide binding protein 2 increases expression ISO triptolide results in increased expression of NUBP2 mRNA CTD PMID:32835833 NCBI chr10:13,903,224...13,906,928
Ensembl chr10:13,903,224...13,906,969
JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO triptolide results in decreased expression of NUDT7 mRNA CTD PMID:32835833 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081
JBrowse link
G Nup210l nucleoporin 210-like increases expression ISO triptolide results in increased expression of NUP210L mRNA CTD PMID:32835833 NCBI chr 2:175,545,999...175,665,332
Ensembl chr 2:175,547,988...175,665,332
JBrowse link
G Nyx nyctalopin increases expression ISO triptolide results in increased expression of NYX mRNA CTD PMID:32835833 NCBI chr  X:9,280,864...9,301,900
Ensembl chr  X:9,280,864...9,301,900
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP triptolide results in increased expression of OASL protein CTD PMID:32519852 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 increases expression ISO triptolide results in increased expression of OAZ3 mRNA CTD PMID:32835833 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
G Ociad2 OCIA domain containing 2 decreases expression ISO triptolide results in decreased expression of OCIAD2 mRNA CTD PMID:32835833 NCBI chr14:34,873,668...34,889,276
Ensembl chr14:34,873,820...34,889,265
JBrowse link
G Ocln occludin multiple interactions
decreases expression
ISO 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of OCLN mRNA]; 10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [triptolide results in decreased expression of OCLN protein]
triptolide results in decreased expression of OCLN mRNA; triptolide results in decreased expression of OCLN protein
CTD PMID:30836114 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Odad4 outer dynein arm docking complex subunit 4 decreases expression ISO triptolide results in decreased expression of TTC25 mRNA CTD PMID:32835833 NCBI chr10:85,480,089...85,508,603
Ensembl chr10:85,480,094...85,508,603
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO triptolide results in increased expression of ODC1 mRNA CTD PMID:32835833 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Odf3b outer dense fiber of sperm tails 3B decreases expression ISO triptolide results in decreased expression of ODF3B mRNA CTD PMID:32835833 NCBI chr 7:120,444,232...120,447,383
Ensembl chr 7:120,444,232...120,446,749
JBrowse link
G Olfm3 olfactomedin 3 decreases expression ISO triptolide results in decreased expression of OLFM3 mRNA CTD PMID:32835833 NCBI chr 2:202,729,610...202,952,120
Ensembl chr 2:202,729,936...202,952,112
JBrowse link
G Olfml1 olfactomedin-like 1 decreases expression ISO triptolide results in decreased expression of OLFML1 mRNA CTD PMID:32835833 NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression EXP triptolide results in increased expression of ORC1 mRNA CTD PMID:23639586 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G Orc3 origin recognition complex, subunit 3 increases expression EXP triptolide results in increased expression of ORC3 mRNA CTD PMID:23639586 NCBI chr 5:49,123,758...49,181,552
Ensembl chr 5:49,126,955...49,181,633
JBrowse link
G Ovca2 OVCA2 serine hydrolase domain containing increases expression ISO triptolide results in increased expression of OVCA2 mRNA CTD PMID:32835833 NCBI chr10:60,026,048...60,029,211 JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP triptolide results in increased expression of P2RX7 protein CTD PMID:32519852 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO triptolide results in increased expression of P4HA1 mRNA CTD PMID:32835833 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like increases expression ISO triptolide results in increased expression of PABPC1L mRNA CTD PMID:32835833 NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997
JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO triptolide results in decreased expression of PANK1 mRNA CTD PMID:32835833 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pard3b par-3 family cell polarity regulator beta decreases expression ISO triptolide results in decreased expression of PARD3B mRNA CTD PMID:32835833 NCBI chr 9:63,038,435...64,067,178
Ensembl chr 9:63,038,436..