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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Triptolide
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Accession:CHEBI:9747 term browser browse the term
Definition:An oxacycle that has formula C20H24O6.
Synonyms:related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-8(2)18-13(25-18)14-20(26-14)17(3)5-4-9-10(7-23-15(9)21)11(17)6-12-19(20,24-12)16(18)22/h8,11-14,16,22H,4-7H2,1-3H3/t11-,12-,13-,14-,16+,17-,18-,19+,20+/m0/s1;   InChIKey=DFBIRQPKNDILPW-CIVMWXNOSA-N;   SMILES=CC(C)[C@]12O[C@H]1[C@@H]1O[C@]11[C@]3(O[C@H]3C[C@H]3C4=C(CC[C@]13C)C(=O)OC4)[C@@H]2O
 xref: CAS:38748-32-2;   KEGG:C09204;   KNApSAcK:C00003494;   LINCS:LSM-5518
 xref_mesh: MESH:C001899
 xref: Wikipedia:Triptolide


show annotations for term's descendants           Sort by:
Triptolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin increases expression ISO triptolide results in increased expression of AAAS mRNA CTD PMID:32835833 NCBI chr 7:135,342,901...135,362,545
Ensembl chr 7:135,342,901...135,362,545 		JBrowse link
G Aadac arylacetamide deacetylase decreases expression ISO triptolide results in decreased expression of AADAC mRNA CTD PMID:32835833 NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 increases expression ISO triptolide results in increased expression of ABCA4 mRNA CTD PMID:32835833 NCBI chr 2:212,849,470...212,986,730
Ensembl chr 2:212,755,803...212,986,729 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression
decreases expression
multiple interactions 		EXP
ISO 		triptolide results in increased expression of ABCB11 protein
triptolide results in decreased expression of ABCB11 mRNA
triptolide results in decreased expression of ABCB11 protein
[triptolide co-treated with Lipopolysaccharides] results in decreased expression of ABCB11 protein; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in decreased expression of ABCB11 protein] 		CTD PMID:32519852 PMID:32987112 PMID:36328986 PMID:36990132 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases response to substance
increases expression
decreases expression 		ISO
EXP 		[ABCB1A mutant form co-treated with triptolide] results in increased abundance of Malondialdehyde; ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]; ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]
ABCB1A protein results in decreased susceptibility to triptolide
triptolide results in increased expression of ABCB1A protein
triptolide results in decreased expression of ABCB1A protein 		CTD PMID:26134275 PMID:32519852 PMID:33600922 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B decreases expression
increases expression 		EXP
ISO 		triptolide results in decreased expression of ABCB1B mRNA
triptolide results in increased expression of ABCB1B mRNA 		CTD PMID:32835833 PMID:33600922 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects expression
decreases expression
multiple interactions 		ISO triptolide affects the expression of ABCC2 protein
triptolide results in decreased expression of ABCC2 protein
[triptolide co-treated with Lipopolysaccharides co-treated with obeticholic acid] results in increased expression of ABCC2 mRNA; [triptolide co-treated with Lipopolysaccharides] results in decreased expression of ABCC2 mRNA; [triptolide co-treated with Lipopolysaccharides] results in decreased expression of ABCC2 protein 		CTD PMID:36328986 PMID:36990132 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases expression 		ISO triptolide results in increased expression of ABCC4 mRNA
triptolide results in decreased expression of ABCC4 protein 		CTD PMID:32835833 PMID:36990132 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 decreases expression ISO triptolide results in decreased expression of ABCD2 mRNA CTD PMID:32835833 NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:124,142,595...124,191,202 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression EXP triptolide results in increased expression of ABCG2 protein CTD PMID:32519852 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression ISO triptolide results in increased expression of ABHD2 mRNA CTD PMID:32835833 NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674 		JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase increases expression ISO triptolide results in increased expression of ABHD5 mRNA CTD PMID:32835833 NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:130,877,703...130,903,947 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO triptolide results in increased expression of ABTB2 mRNA CTD PMID:32835833 NCBI chr 3:110,409,672...110,563,488
Ensembl chr 3:110,409,627...110,563,487 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B decreases expression EXP triptolide results in decreased expression of ACAA1B protein CTD PMID:32519852 NCBI chr 8:127,750,771...127,759,589
Ensembl chr 8:127,750,743...127,759,569 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation ISO triptolide results in increased phosphorylation of ACACA protein CTD PMID:29723566 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression ISO triptolide results in decreased expression of ACACB mRNA CTD PMID:32835833 NCBI chr12:48,026,394...48,138,214
Ensembl chr12:48,026,394...48,138,214 		JBrowse link
G Acly ATP citrate lyase decreases expression ISO triptolide results in decreased expression of ACLY mRNA CTD PMID:32835833 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 decreases expression
increases expression 		ISO
EXP 		triptolide results in decreased expression of ACOT1 mRNA
triptolide results in increased expression of ACOT1 protein 		CTD PMID:31241159 PMID:32519852 NCBI chr 6:109,367,274...109,375,268
Ensembl chr 6:109,367,268...109,380,749 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO triptolide results in increased expression of ACOT2 mRNA CTD PMID:32835833 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO triptolide results in increased expression of ACOT3 mRNA CTD PMID:32835833 NCBI chr 6:109,413,617...109,419,840
Ensembl chr 6:109,413,534...109,421,427
Ensembl chr 6:109,413,534...109,421,427 		JBrowse link
G Acot9 acyl-CoA thioesterase 9 increases expression ISO triptolide results in increased expression of ACOT9 mRNA CTD PMID:32835833 NCBI chr  X:43,922,943...43,973,311
Ensembl chr  X:43,914,923...43,973,205 		JBrowse link
G Acox2 acyl-CoA oxidase 2 decreases expression
increases expression 		ISO
EXP 		triptolide results in decreased expression of ACOX2 mRNA
triptolide results in increased expression of ACOX2 protein 		CTD PMID:31241159 PMID:32519852 NCBI chr15:19,090,820...19,122,392
Ensembl chr15:19,090,926...19,122,392 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression ISO triptolide results in decreased expression of ACSL5 mRNA CTD PMID:32835833 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression EXP triptolide results in decreased expression of ACSM1 protein CTD PMID:32519852 NCBI chr 1:183,417,052...183,451,897
Ensembl chr 1:183,416,009...183,454,217 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 decreases expression EXP triptolide results in decreased expression of ACSM2 protein CTD PMID:32519852 NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:183,347,705...183,386,453 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression ISO triptolide results in decreased expression of ACSS2 mRNA CTD PMID:32835833 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830 		JBrowse link
G Actb actin, beta decreases expression EXP triptolide results in decreased expression of ACTB mRNA; triptolide results in decreased expression of ACTB protein CTD PMID:27554044 NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242 		JBrowse link
G Ada adenosine deaminase increases expression EXP triptolide results in increased expression of ADA protein CTD PMID:32519852 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adam11 ADAM metallopeptidase domain 11 decreases expression ISO triptolide results in decreased expression of ADAM11 mRNA CTD PMID:32835833 NCBI chr10:88,224,185...88,242,865
Ensembl chr10:88,224,347...88,242,864 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a increases expression ISO triptolide results in increased expression of ADAM1A mRNA CTD PMID:32835833 NCBI chr12:40,674,460...40,680,988
Ensembl chr12:40,676,918...40,684,619 		JBrowse link
G Adam2 ADAM metallopeptidase domain 2 increases expression ISO triptolide results in increased expression of ADAM2 mRNA CTD PMID:32835833 NCBI chr15:44,418,191...44,459,570
Ensembl chr15:44,418,199...44,459,516 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 increases expression ISO triptolide results in increased expression of ADAMTS1 mRNA CTD PMID:32835833 NCBI chr11:38,418,565...38,427,384
Ensembl chr11:38,418,101...38,427,390 		JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of ADGRE1 mRNA
STING1 protein affects the reaction [triptolide results in decreased expression of ADGRE1 mRNA] 		CTD PMID:36520315 NCBI chr 9:2,329,398...2,484,959
Ensembl chr 9:2,329,438...2,484,959 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO triptolide results in decreased expression of ADGRF1 mRNA CTD PMID:32835833 NCBI chr 9:25,158,198...25,210,744
Ensembl chr 9:25,147,588...25,208,916 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide decreases expression EXP triptolide results in decreased expression of ADH1 mRNA CTD PMID:23639586 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291 		JBrowse link
G Adpgk ADP-dependent glucokinase increases expression EXP
ISO 		triptolide results in increased expression of ADPGK mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 8:68,595,194...68,623,179
Ensembl chr 8:68,595,248...68,623,178 		JBrowse link
G Aen apoptosis enhancing nuclease increases expression ISO triptolide results in increased expression of AEN mRNA CTD PMID:32835833 NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:142,224,493...142,233,898 		JBrowse link
G Afg2a AFG2 AAA ATPase homolog A increases expression ISO triptolide results in increased expression of AFG2A mRNA CTD PMID:32835833 NCBI chr 2:122,234,619...122,425,808
Ensembl chr 2:122,234,738...122,425,808 		JBrowse link
G Afg3l1 AFG3 (ATPase family gene 3)-like 1 increases expression EXP triptolide results in increased expression of AFG3L1 protein CTD PMID:32519852 NCBI chr19:68,417,101...68,444,260
Ensembl chr19:68,417,082...68,446,039 		JBrowse link
G Afm afamin increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of AFM protein
triptolide results in decreased expression of AFM mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039 		JBrowse link
G Afmid arylformamidase decreases expression ISO triptolide results in decreased expression of AFMID mRNA CTD PMID:32835833 NCBI chr10:103,544,822...103,560,408
Ensembl chr10:103,544,841...103,560,408 		JBrowse link
G Agpat5 1-acylglycerol-3-phosphate O-acyltransferase 5 increases expression ISO triptolide results in increased expression of AGPAT5 mRNA CTD PMID:32835833 NCBI chr16:77,641,887...77,688,148
Ensembl chr16:77,641,887...77,688,148 		JBrowse link
G Agps alkylglycerone phosphate synthase increases expression EXP triptolide results in increased expression of AGPS protein CTD PMID:32519852 NCBI chr 3:81,154,599...81,253,099
Ensembl chr 3:81,154,604...81,258,277 		JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO triptolide results in decreased expression of AHCY mRNA CTD PMID:32835833 NCBI chr 3:164,029,338...164,044,562
Ensembl chr 3:164,029,338...164,044,587 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression ISO triptolide results in decreased expression of AIFM1 protein CTD PMID:26990902 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression EXP triptolide results in increased expression of AKR1B1 protein CTD PMID:32519852 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 decreases expression EXP triptolide results in decreased expression of AKR1B10 protein CTD PMID:32519852 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847 		JBrowse link
G Akr1b15 aldo-keto reductase family 1 member B15 increases expression EXP triptolide results in increased expression of AKR1B8 protein CTD PMID:32519852 NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression ISO triptolide results in decreased expression of AKR1C6 mRNA CTD PMID:32835833 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP triptolide results in increased expression of AKR7A2 protein CTD PMID:32519852 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation 		EXP
ISO 		triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of AKT1 protein]
triptolide results in decreased phosphorylation of AKT1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein] 		CTD PMID:21717513 PMID:32061799 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression EXP triptolide results in decreased expression of AKT2 mRNA CTD PMID:23639586 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Alb albumin increases expression EXP triptolide results in increased expression of ALB protein CTD PMID:32519852 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 decreases expression ISO triptolide results in decreased expression of ALDH1L1 mRNA CTD PMID:32835833 NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B decreases expression EXP
ISO 		triptolide results in decreased expression of ALDOB mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:68,684,542...68,716,740 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO triptolide results in decreased expression of ALDOC mRNA CTD PMID:32835833 NCBI chr10:63,715,544...63,719,133
Ensembl chr10:63,715,489...63,719,133 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [triptolide co-treated with FASL protein] results in increased expression of ALPL protein CTD PMID:37944651 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase affects expression EXP triptolide affects the expression of AMACR protein CTD PMID:32519852 NCBI chr 2:61,673,291...61,685,381
Ensembl chr 2:61,670,475...61,685,379 		JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor increases expression EXP triptolide results in increased expression of AMBP protein CTD PMID:32519852 NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:81,583,622...81,593,850 		JBrowse link
G Amh anti-Mullerian hormone increases expression ISO triptolide results in increased expression of AMH mRNA CTD PMID:32835833 NCBI chr 7:9,557,451...9,559,867
Ensembl chr 7:9,557,451...9,559,867 		JBrowse link
G Ankmy1 ankyrin repeat and MYND domain containing 1 increases expression ISO triptolide results in increased expression of ANKMY1 mRNA CTD PMID:32835833 NCBI chr 9:100,869,899...100,924,030
Ensembl chr 9:100,871,373...100,924,229 		JBrowse link
G Ankrd13a ankyrin repeat domain 13a increases expression ISO triptolide results in increased expression of ANKRD13A mRNA CTD PMID:32835833 NCBI chr12:47,458,828...47,488,959
Ensembl chr12:47,458,831...47,489,312 		JBrowse link
G Ano6 anoctamin 6 increases expression EXP triptolide results in increased expression of ANO6 protein CTD PMID:32519852 NCBI chr 7:128,812,842...128,992,805
Ensembl chr 7:128,813,068...128,992,799 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP triptolide results in increased expression of ANP32E protein CTD PMID:32519852 NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986 		JBrowse link
G Anpep alanyl aminopeptidase, membrane affects expression EXP triptolide affects the expression of ANPEP protein CTD PMID:32519852 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101 		JBrowse link
G Anxa13 annexin A13 increases expression EXP triptolide results in increased expression of ANXA13 protein CTD PMID:32519852 NCBI chr 7:91,773,844...91,826,386
Ensembl chr 7:91,770,861...91,826,386 		JBrowse link
G Anxa9 annexin A9 increases expression ISO triptolide results in increased expression of ANXA9 mRNA CTD PMID:32835833 NCBI chr 2:185,562,174...185,572,560
Ensembl chr 2:185,562,174...185,572,560 		JBrowse link
G Aoc2-ps1 amine oxidase, copper containing 2, pseudogene 1 increases expression ISO triptolide results in increased expression of AOC2 mRNA CTD PMID:32835833 NCBI chr10:86,767,268...86,768,734 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression
multiple interactions 		ISO
EXP 		triptolide results in increased expression of APAF1 protein
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein] 		CTD PMID:25169008 PMID:26990902 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 affects expression ISO triptolide affects the expression of APEX2 mRNA CTD PMID:32835833 NCBI chr  X:22,914,943...22,937,713
Ensembl chr  X:22,914,944...22,936,011 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression EXP triptolide results in increased expression of APOA1 protein CTD PMID:32519852 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Aqp1 aquaporin 1 increases expression EXP triptolide results in increased expression of AQP1 protein CTD PMID:32519852 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:85,812,784...85,830,504 		JBrowse link
G Aqp2 aquaporin 2 increases expression EXP triptolide results in increased expression of AQP2 protein CTD PMID:32519852 NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319 		JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO triptolide results in decreased expression of AQP4 mRNA CTD PMID:32835833 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,782,389...6,799,098 		JBrowse link
G Aqp8 aquaporin 8 decreases expression ISO triptolide results in decreased expression of AQP8 mRNA CTD PMID:32835833 NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO triptolide results in increased expression of ARC mRNA CTD PMID:32835833 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220 		JBrowse link
G Arglu1 arginine and glutamate rich 1 increases expression EXP triptolide results in increased expression of ARGLU1 protein CTD PMID:32519852 NCBI chr16:87,455,097...87,479,148
Ensembl chr16:87,455,113...87,479,148 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 decreases expression ISO triptolide results in decreased expression of ARHGEF16 mRNA CTD PMID:32835833 NCBI chr 5:170,126,573...170,148,624
Ensembl chr 5:170,126,575...170,148,624 		JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 decreases expression ISO triptolide results in decreased expression of ARHGEF37 mRNA CTD PMID:32835833 NCBI chr18:57,205,621...57,271,284
Ensembl chr18:57,230,117...57,271,031 		JBrowse link
G Arid1a AT-rich interaction domain 1A increases expression ISO triptolide results in increased expression of ARID1A mRNA CTD PMID:32835833 NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO triptolide results in increased expression of ARID5A mRNA CTD PMID:32835833 NCBI chr 9:46,030,513...46,058,729
Ensembl chr 9:46,030,548...46,045,363 		JBrowse link
G Arl8b ARF like GTPase 8B decreases expression EXP triptolide results in decreased expression of ARL8B protein CTD PMID:32519852 NCBI chr 4:143,304,597...143,348,580
Ensembl chr 4:143,304,621...143,349,068 		JBrowse link
G Armc9 armadillo repeat containing 9 increases expression EXP triptolide results in increased expression of ARMC9 protein CTD PMID:32519852 NCBI chr 9:94,250,492...94,376,589
Ensembl chr 9:94,250,859...94,376,589 		JBrowse link
G Arrb1 arrestin, beta 1 increases expression EXP triptolide results in increased expression of ARRB1 protein CTD PMID:32519852 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Ascl3 achaete-scute family bHLH transcription factor 3 increases expression ISO triptolide results in increased expression of ASCL3 mRNA CTD PMID:32835833 NCBI chr 1:173,190,061...173,194,302
Ensembl chr 1:173,190,228...173,192,197 		JBrowse link
G Asgr1 asialoglycoprotein receptor 1 decreases expression ISO triptolide results in decreased expression of ASGR1 mRNA CTD PMID:32835833 NCBI chr10:55,274,299...55,278,323
Ensembl chr10:55,274,706...55,278,322 		JBrowse link
G Asl argininosuccinate lyase decreases expression ISO triptolide results in decreased expression of ASL mRNA CTD PMID:32835833 NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP triptolide results in increased expression of ASNS protein CTD PMID:32519852 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP
ISO 		triptolide results in decreased expression of ASS1 protein
triptolide results in decreased expression of ASS1 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO triptolide results in increased expression of ATF3 mRNA CTD PMID:32835833 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression
multiple interactions
increases expression 		EXP
ISO 		triptolide results in decreased expression of ATF4 mRNA
STING1 protein affects the reaction [triptolide results in increased expression of ATF4 protein]; TRAJ18 protein affects the reaction [triptolide results in increased expression of ATF4 mRNA]
triptolide results in increased expression of ATF4 mRNA; triptolide results in increased expression of ATF4 protein 		CTD PMID:23639586 PMID:36520315 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO triptolide results in decreased expression of ATF5 mRNA CTD PMID:32835833 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183 		JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression
multiple interactions 		ISO triptolide results in decreased expression of ATF6 protein
triptolide results in increased expression of ATF6 mRNA
STING1 protein affects the reaction [triptolide results in increased expression of ATF6 mRNA]; STING1 protein affects the reaction [triptolide results in increased expression of ATF6 protein] 		CTD PMID:26990902 PMID:36520315 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033 		JBrowse link
G Atf6b activating transcription factor 6 beta decreases expression ISO triptolide results in decreased expression of ATF6B protein CTD PMID:26990902 NCBI chr20:4,095,534...4,103,534
Ensembl chr20:4,095,534...4,106,032 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO triptolide results in increased expression of ATG12 protein CTD PMID:26990902 NCBI chr18:41,638,841...41,649,311
Ensembl chr18:41,635,835...41,649,261 		JBrowse link
G Atg5 autophagy related 5 increases expression ISO triptolide results in increased expression of ATG5 protein CTD PMID:26990902 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821 		JBrowse link
G Atg7 autophagy related 7 increases expression ISO triptolide results in increased expression of ATG7 protein CTD PMID:26990902 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Atp11a ATPase phospholipid transporting 11A increases expression EXP triptolide results in increased expression of ATP11A protein CTD PMID:32519852 NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions
decreases expression 		EXP
ISO 		7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]
triptolide results in decreased expression of ATP5F1A mRNA; triptolide results in decreased expression of ATP5F1A protein 		CTD PMID:36436616 NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP triptolide results in decreased expression of ATP5F1E protein CTD PMID:32519852 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214 		JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 increases expression EXP triptolide results in increased expression of ATP5MC3 protein CTD PMID:32519852 NCBI chr 3:79,218,014...79,220,664
Ensembl chr 3:79,218,014...79,220,664 		JBrowse link
G Atp5me ATP synthase membrane subunit e increases expression EXP triptolide results in increased expression of ATP5ME protein CTD PMID:32519852 NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,464,800...1,465,988 		JBrowse link
G Atp5mj ATP synthase membrane subunit j decreases expression EXP triptolide results in decreased expression of ATP5MJ protein CTD PMID:32519852 NCBI chr 6:136,839,890...136,845,640
Ensembl chr 1:177,906,475...177,907,045
Ensembl chr 1:177,906,475...177,907,045 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression EXP triptolide results in increased expression of ATP6V0A1 protein CTD PMID:32519852 NCBI chr10:86,436,089...86,490,185
Ensembl chr10:86,436,141...86,490,181 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 increases expression EXP triptolide results in increased expression of ATP6V0A4 protein CTD PMID:32519852 NCBI chr 4:67,727,145...67,809,092
Ensembl chr 4:67,727,145...67,809,092 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C increases expression EXP triptolide results in increased expression of ATP6V0C protein CTD PMID:32519852 NCBI chr10:13,700,764...13,707,147
Ensembl chr10:13,700,764...13,706,245 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 increases expression EXP triptolide results in increased expression of ATP6V0D1 protein CTD PMID:32519852 NCBI chr19:50,313,268...50,357,248
Ensembl chr19:50,313,273...50,357,395 		JBrowse link
G Atp8b5 ATPase, class I, type 8B, member 5 increases expression ISO triptolide results in increased expression of ATP8B5 mRNA CTD PMID:32835833 NCBI chr 5:62,302,213...62,415,843
Ensembl chr 5:62,302,275...62,415,834 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO triptolide results in increased expression of B4GALT1 mRNA CTD PMID:32835833 NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445 		JBrowse link
G Bag3 BAG cochaperone 3 increases expression ISO triptolide results in increased expression of BAG3 mRNA CTD PMID:32835833 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280 		JBrowse link
G Baiap3 BAI1-associated protein 3 increases expression ISO triptolide results in increased expression of BAIAP3 mRNA CTD PMID:32835833 NCBI chr10:14,764,768...14,777,516
Ensembl chr10:14,756,693...14,777,516 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression 		EXP
ISO 		pifithrin inhibits the reaction [triptolide results in increased expression of BAK1 protein]
TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAK1 protein] 		CTD PMID:30009776 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
affects expression 		EXP
ISO 		NFE2L2 protein inhibits the reaction [triptolide results in increased expression of BAX protein]; pifithrin inhibits the reaction [triptolide results in increased expression of BAX protein]; Quercetin inhibits the reaction [triptolide affects the expression of BAX protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of BAX protein]
ABCB1A mutant form promotes the reaction [triptolide results in increased expression of BAX protein]; bergenin inhibits the reaction [triptolide results in increased expression of BAX protein]; Estradiol inhibits the reaction [triptolide results in increased expression of BAX protein]; mitoquinone inhibits the reaction [triptolide results in increased expression of BAX protein]; tariquidar promotes the reaction [triptolide results in increased expression of BAX protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAX protein]
triptolide results in increased expression of BAX mRNA; triptolide results in increased expression of BAX protein 		CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression EXP triptolide results in increased expression of BBC3 protein CTD PMID:30009776 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
affects expression
increases expression 		EXP
ISO 		triptolide results in decreased expression of BCL2 protein
Lithium Chloride inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; Quercetin inhibits the reaction [triptolide affects the expression of BCL2 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
ABCB1A mutant form promotes the reaction [triptolide results in decreased expression of BCL2 protein]; bergenin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; Estradiol inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; FASL protein promotes the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; tariquidar promotes the reaction [triptolide results in decreased expression of BCL2 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]
triptolide results in increased expression of BCL2 protein 		CTD PMID:25169008 PMID:26134275 PMID:26277538 PMID:26990902 PMID:30009776 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
decreases expression 		ISO
EXP 		triptolide results in increased expression of BCL2L1 protein
pifithrin inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]
TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein] 		CTD PMID:26990902 PMID:30009776 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl2l14 Bcl2-like 14 increases expression ISO triptolide results in increased expression of BCL2L14 mRNA CTD PMID:32835833 NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:168,948,946...168,990,079 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO triptolide results in decreased expression of BDH2 mRNA CTD PMID:32835833 NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006 		JBrowse link
G Becn1 beclin 1 increases expression ISO triptolide results in increased expression of BECN1 protein CTD PMID:26990902 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bfsp1 beaded filament structural protein 1 increases expression ISO triptolide results in increased expression of BFSP1 mRNA CTD PMID:32835833 NCBI chr 3:151,648,588...151,706,153
Ensembl chr 3:151,648,588...151,682,837 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO triptolide results in decreased expression of BHLHE40 mRNA CTD PMID:32835833 NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO triptolide results in increased expression of BID protein CTD PMID:26990902 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:155,785,377...155,808,275 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO triptolide results in decreased expression of BIRC3 mRNA CTD PMID:15972136 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Blvra biliverdin reductase A affects expression EXP triptolide affects the expression of BLVRA protein CTD PMID:32519852 NCBI chr 3:134,793,397...134,819,367
Ensembl chr 3:134,794,203...134,819,785 		JBrowse link
G Bmf Bcl2 modifying factor decreases expression ISO triptolide results in decreased expression of BMF mRNA CTD PMID:32835833 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:125,953,466...125,974,258 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression ISO triptolide results in increased expression of BOP1 mRNA CTD PMID:32835833 NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529 		JBrowse link
G Bsnd barttin CLCNK type accessory subunit beta decreases expression EXP triptolide results in decreased expression of BSND protein CTD PMID:32519852 NCBI chr 5:126,480,590...126,489,389
Ensembl chr 5:126,480,592...126,489,389 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression EXP triptolide results in increased expression of BST2 protein CTD PMID:32519852 NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967 		JBrowse link
G Btaf1 B-TFIID TATA-box binding protein associated factor 1 increases expression ISO triptolide results in increased expression of BTAF1 mRNA CTD PMID:32835833 NCBI chr 1:244,065,728...244,156,457
Ensembl chr 1:244,065,743...244,156,457 		JBrowse link
G Btbd10 BTB domain containing 10 increases expression ISO triptolide results in increased expression of BTBD10 mRNA CTD PMID:32835833 NCBI chr 1:176,865,817...176,923,663
Ensembl chr 1:176,865,817...176,923,663 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO triptolide results in increased expression of BTG3 mRNA CTD PMID:32835833 NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082 		JBrowse link
G Btnl9 butyrophilin-like 9 increases expression ISO triptolide results in increased expression of BTNL9 mRNA CTD PMID:32835833 NCBI chr10:33,967,098...33,990,304
Ensembl chr10:33,970,675...33,990,354 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression
increases expression 		EXP triptolide results in decreased expression of BUB1 mRNA
triptolide results in increased expression of BUB1 mRNA 		CTD PMID:23639586 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression EXP triptolide results in increased expression of BUB1B mRNA CTD PMID:23639586 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression EXP triptolide results in decreased expression of BUB3 mRNA CTD PMID:23639586 NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028 		JBrowse link
G C11h21orf91 similar to human chromosome 21 open reading frame 91 increases expression ISO triptolide results in increased expression of D16ERTD472E mRNA CTD PMID:32835833 NCBI chr11:30,716,034...30,749,292
Ensembl chr11:30,716,034...30,749,415 		JBrowse link
G C1qa complement C1q A chain increases expression EXP triptolide results in increased expression of C1QA protein CTD PMID:32519852 NCBI chr 5:154,417,086...154,419,933
Ensembl chr 5:154,417,087...154,427,732 		JBrowse link
G C3 complement C3 increases expression EXP triptolide results in increased expression of C3 protein CTD PMID:32519852 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339 		JBrowse link
G C4a complement C4A increases expression EXP triptolide results in increased expression of C4A protein CTD PMID:32519852 NCBI chr20:4,010,306...4,024,707 JBrowse link
G Ca1 carbonic anhydrase 1 increases expression EXP triptolide results in increased expression of CA1 protein CTD PMID:32519852 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca14 carbonic anhydrase 14 decreases expression ISO triptolide results in decreased expression of CAR14 mRNA CTD PMID:32835833 NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:186,129,341...186,138,863 		JBrowse link
G Ca3 carbonic anhydrase 3 increases expression EXP triptolide results in increased expression of CA3 protein CTD PMID:32519852 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CA9 protein] CTD PMID:24842335 NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626 		JBrowse link
G Cabcoco1 ciliary associated calcium binding coiled-coil 1 decreases expression ISO triptolide results in decreased expression of CABCOCO1 mRNA CTD PMID:32835833 NCBI chr20:20,057,462...20,166,732
Ensembl chr20:20,057,517...20,167,174 		JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO triptolide results in increased expression of CABYR mRNA CTD PMID:32835833 NCBI chr18:4,166,790...4,178,570
Ensembl chr18:4,166,858...4,179,507 		JBrowse link
G Cald1 caldesmon 1 decreases expression EXP triptolide results in decreased expression of CALD1 protein CTD PMID:32519852 NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085 		JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO triptolide results in increased expression of CAMTA2 mRNA CTD PMID:32835833 NCBI chr10:55,882,071...55,900,575
Ensembl chr10:55,882,071...55,900,179 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression EXP triptolide results in increased expression of CAPG protein CTD PMID:32519852 NCBI chr 4:106,152,912...106,170,010
Ensembl chr 4:106,152,890...106,170,672 		JBrowse link
G Capn1 calpain 1 increases expression ISO triptolide results in increased expression of CAPN1 protein CTD PMID:26990902 NCBI chr 1:212,705,219...212,736,134
Ensembl chr 1:212,705,222...212,729,445 		JBrowse link
G Capn2 calpain 2 increases expression ISO triptolide results in increased expression of CAPN2 protein CTD PMID:26990902 NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625 		JBrowse link
G Caps calcyphosine increases expression ISO triptolide results in increased expression of TNFRSF23 mRNA CTD PMID:32835833 NCBI chr 9:1,630,871...1,632,758 JBrowse link
G Carf calcium responsive transcription factor increases expression ISO triptolide results in increased expression of CARF mRNA CTD PMID:32835833 NCBI chr 9:68,996,419...69,046,480
Ensembl chr 9:68,996,250...69,046,479 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP triptolide results in decreased expression of CARHSP1 protein CTD PMID:32519852 NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770 		JBrowse link
G Carmil1 capping protein regulator and myosin 1 linker 1 decreases expression ISO triptolide results in decreased expression of CARMIL1 mRNA CTD PMID:32835833 NCBI chr17:41,235,819...41,516,204
Ensembl chr17:41,236,229...41,516,221 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 increases expression ISO triptolide results in increased expression of RLTPR mRNA CTD PMID:32835833 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:50,484,324...50,496,669 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP1 mRNA; [triptolide co-treated with TNF protein] results in increased cleavage of CASP1 protein; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased cleavage of CASP1 protein] CTD PMID:36328986 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp12 caspase 12 increases expression ISO triptolide results in increased expression of CASP12 protein CTD PMID:26990902 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression 		ISO
EXP 		NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; TP53 protein affects the reaction [triptolide results in increased cleavage of CASP3 protein]; triptolide results in increased activity of and results in increased cleavage of CASP3 protein
triptolide results in increased activity of CASP3 protein
3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; pifithrin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP3 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]
[triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form]; bergenin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; CASP3 inhibits the reaction [[triptolide co-treated with FASL protein] results in increased cleavage of XIAP protein]; Estradiol inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; FASL protein promotes the reaction [triptolide results in increased cleavage of and results in increased activity of CASP3 protein]; mitoquinone inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of CASP3 protein modified form]; TRAJ18 protein affects the reaction [triptolide results in increased cleavage of CASP3 protein]; triptolide results in increased cleavage of and results in increased activity of CASP3 protein; triptolide results in increased expression of and results in increased activity of CASP3 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased cleavage of CASP3 protein] 		CTD PMID:12533674 PMID:15972136 PMID:19233258 PMID:21640813 PMID:23639586 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp4 caspase 4 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased cleavage of CASP4 protein; GW 4064 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased cleavage of CASP4 protein]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased cleavage of CASP4 protein] CTD PMID:36328986 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:10,883,769...10,920,727 		JBrowse link
G Casp7 caspase 7 increases activity
increases expression 		ISO
EXP 		triptolide results in increased activity of CASP7 protein
triptolide results in increased expression of CASP7 protein 		CTD PMID:21640813 PMID:32519852 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form; triptolide results in increased expression of and results in increased activity of CASP8 protein CTD PMID:26990902 PMID:30633930 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression
increases cleavage 		EXP
ISO 		pifithrin inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]; Quercetin inhibits the reaction [triptolide results in increased activity of CASP9 protein]; Val-Pro-Met-Leu-Lys inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]
bergenin inhibits the reaction [triptolide results in increased cleavage of CASP9 protein]; Estradiol inhibits the reaction [triptolide results in increased cleavage of CASP9 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in increased cleavage of CASP9 protein]]; triptolide results in increased expression of and results in increased activity of CASP9 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form] 		CTD PMID:26277538 PMID:26990902 PMID:30009776 PMID:32835833 PMID:38735593 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 increases expression EXP triptolide results in increased expression of CASTOR1 protein CTD PMID:32519852 NCBI chr14:83,309,710...83,314,123
Ensembl chr14:83,309,504...83,314,127 		JBrowse link
G Cat catalase decreases activity
multiple interactions 		ISO triptolide results in decreased activity of CAT protein
Chlormethiazole inhibits the reaction [triptolide results in decreased activity of CAT protein]; pyrazole promotes the reaction [triptolide results in decreased activity of CAT protein]
bergenin inhibits the reaction [triptolide results in decreased activity of CAT protein]; Chlormethiazole inhibits the reaction [triptolide results in decreased activity of CAT protein]; Estradiol inhibits the reaction [triptolide results in decreased activity of CAT protein]; pyrazole promotes the reaction [triptolide results in decreased activity of CAT protein]; XDH protein inhibits the reaction [bergenin inhibits the reaction [triptolide results in decreased activity of CAT protein]] 		CTD PMID:34758665 PMID:38735593 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 increases expression EXP triptolide results in increased expression of CAV1 protein CTD PMID:32519852 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression ISO triptolide results in increased expression of CBARP mRNA CTD PMID:32835833 NCBI chr 7:10,217,314...10,225,855
Ensembl chr 7:10,217,328...10,225,854 		JBrowse link
G Cblc Cbl proto-oncogene C decreases expression EXP triptolide results in decreased expression of CBLC mRNA CTD PMID:23639586 NCBI chr 1:88,567,930...88,584,709
Ensembl chr 1:88,567,932...88,584,709 		JBrowse link
G Cbr3 carbonyl reductase 3 increases expression ISO triptolide results in increased expression of CBR3 mRNA CTD PMID:32835833 NCBI chr11:46,478,295...46,486,555
Ensembl chr11:46,478,274...46,486,558 		JBrowse link
G Ccdc120 coiled-coil domain containing 120 increases expression ISO triptolide results in increased expression of CCDC120 mRNA CTD PMID:32835833 NCBI chr  X:17,437,219...17,443,716
Ensembl chr  X:17,425,624...17,444,717 		JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression ISO triptolide results in increased expression of CCDC15 mRNA CTD PMID:32835833 NCBI chr 8:45,165,297...45,257,641
Ensembl chr 8:45,134,596...45,277,989 		JBrowse link
G Ccdc180 coiled-coil domain containing 180 increases expression ISO triptolide results in increased expression of CCDC180 mRNA CTD PMID:32835833 NCBI chr 5:64,950,522...65,019,127
Ensembl chr 5:64,950,515...65,019,127 		JBrowse link
G Ccdc196 coiled-coil domain containing 196 increases expression EXP triptolide results in increased expression of CCDC196 protein CTD PMID:32519852 NCBI chr 6:102,646,156...102,672,145
Ensembl chr 6:102,648,953...102,664,225 		JBrowse link
G Ccdc62 coiled-coil domain containing 62 increases expression ISO triptolide results in increased expression of CCDC62 mRNA CTD PMID:32835833 NCBI chr12:38,284,089...38,320,828
Ensembl chr12:38,284,089...38,320,965 		JBrowse link
G Ccdc86 coiled-coil domain containing 86 increases expression ISO triptolide results in increased expression of CCDC86 mRNA CTD PMID:32835833 NCBI chr 1:217,015,059...217,021,439
Ensembl chr 1:217,014,848...217,021,468 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
multiple interactions 		ISO triptolide results in increased expression of CCL11 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA] 		CTD PMID:24949944 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression 		ISO triptolide promotes the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
triptolide results in increased expression of CCL2 mRNA 		CTD PMID:30633930 PMID:32835833 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccna1 cyclin A1 decreases expression ISO triptolide results in decreased expression of CCNA1 protein CTD PMID:12533674 NCBI chr 2:141,383,352...141,428,205
Ensembl chr 2:141,382,468...141,393,300 		JBrowse link
G Ccna2 cyclin A2 increases expression EXP triptolide results in increased expression of CCNA2 mRNA CTD PMID:23639586 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Ccnb1 cyclin B1 increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of CCNB1 mRNA
triptolide results in decreased expression of CCNB1 protein 		CTD PMID:12533674 PMID:23639586 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnb2 cyclin B2 increases expression EXP triptolide results in increased expression of CCNB2 mRNA CTD PMID:23639586 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP
ISO 		triptolide results in decreased expression of CCND1 mRNA
triptolide results in decreased expression of CCND1 protein 		CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP triptolide results in increased expression of CCND2 mRNA CTD PMID:23639586 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Ccne1 cyclin E1 increases expression ISO triptolide results in increased expression of CCNE1 protein CTD PMID:26990902 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822 		JBrowse link
G Ccne2 cyclin E2 increases expression EXP triptolide results in increased expression of CCNE2 mRNA CTD PMID:23639586 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO triptolide results in increased expression of CCNG1 mRNA CTD PMID:32835833 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766 		JBrowse link
G Cd1d1 CD1d1 molecule increases expression
multiple interactions 		ISO triptolide results in increased expression of CD1D1 protein
STING1 protein affects the reaction [triptolide results in increased expression of CD1D1 protein] 		CTD PMID:36520315 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029 		JBrowse link
G Cd24 CD24 molecule multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD24 protein] CTD PMID:24842335 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785 		JBrowse link
G Cd36 CD36 molecule increases expression EXP triptolide results in increased expression of CD36 protein CTD PMID:32519852 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd40 CD40 molecule multiple interactions
affects expression 		ISO STING1 protein affects the reaction [triptolide affects the expression of CD40 protein] CTD PMID:36520315 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of CD44 protein] CTD PMID:24842335 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cd47 Cd47 molecule increases expression EXP triptolide results in increased expression of CD47 protein CTD PMID:32519852 NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272 		JBrowse link
G Cd59b CD59b molecule increases expression EXP triptolide results in increased expression of CD59 protein CTD PMID:32519852 NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310 		JBrowse link
G Cd68 Cd68 molecule multiple interactions
decreases expression 		ISO STING1 protein affects the reaction [triptolide results in decreased expression of CD68 mRNA] CTD PMID:36520315 NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540 		JBrowse link
G Cd69 Cd69 molecule multiple interactions
increases expression 		ISO STING1 protein affects the reaction [triptolide results in increased expression of CD69 protein] CTD PMID:36520315 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:164,411,485...164,419,509 		JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein] CTD PMID:15663903 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540 		JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression 		ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein]
triptolide results in increased expression of CD86 protein 		CTD PMID:15663903 PMID:36520315 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361 		JBrowse link
G Cdc16 cell division cycle 16 decreases expression EXP triptolide results in decreased expression of CDC16 mRNA CTD PMID:23639586 NCBI chr16:82,475,234...82,498,797
Ensembl chr16:82,474,523...82,498,765 		JBrowse link
G Cdc25b cell division cycle 25B increases expression EXP triptolide results in increased expression of CDC25B mRNA CTD PMID:23639586 NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:138,860,130...138,870,492 		JBrowse link
G Cdc42 cell division cycle 42 decreases expression EXP triptolide results in decreased expression of CDC42 mRNA; triptolide results in decreased expression of CDC42 protein CTD PMID:27554044 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Cdc45 cell division cycle 45 increases expression EXP triptolide results in increased expression of CDC45 mRNA CTD PMID:23639586 NCBI chr11:95,689,702...95,714,980
Ensembl chr11:95,689,919...95,714,981 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of CDK1 mRNA
triptolide results in decreased expression of CDK1 protein 		CTD PMID:12533674 PMID:23639586 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
increases expression 		EXP
ISO 		triptolide results in decreased expression of CDK2 mRNA
triptolide results in increased expression of CDK2 protein
triptolide results in decreased expression of CDK2 protein 		CTD PMID:12533674 PMID:23639586 PMID:26990902 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression ISO triptolide results in increased expression of CDK4 protein CTD PMID:26990902 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 increases expression ISO triptolide results in increased expression of CDK6 protein CTD PMID:26990902 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:31,601,192...31,781,701 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression EXP triptolide results in increased expression of CDK7 mRNA CTD PMID:23639586 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485 		JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO triptolide results in increased expression of CDKL3 mRNA CTD PMID:32835833 NCBI chr10:36,755,413...36,850,197
Ensembl chr10:36,764,377...36,878,660 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
affects expression
multiple interactions 		EXP
ISO 		triptolide results in increased expression of CDKN1A mRNA
triptolide results in increased expression of CDKN1A mRNA; triptolide results in increased expression of CDKN1A protein
triptolide affects the expression of CDKN1A protein
NFE2L2 protein inhibits the reaction [triptolide affects the expression of CDKN1A protein]; sulforaphane inhibits the reaction [triptolide affects the expression of CDKN1A protein] 		CTD PMID:23639586 PMID:26990902 PMID:32835833 PMID:36990132 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP triptolide results in increased expression of CDKN1B protein CTD PMID:32519852 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression EXP triptolide results in increased expression of CDKN2C mRNA CTD PMID:23639586 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891 		JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression ISO triptolide results in increased expression of CDNF mRNA CTD PMID:32835833 NCBI chr17:79,623,728...79,637,800
Ensembl chr17:79,611,623...79,665,922 		JBrowse link
G Cep170b centrosomal protein 170B increases expression ISO triptolide results in increased expression of CEP170B mRNA CTD PMID:32835833 NCBI chr 6:137,602,707...137,627,750
Ensembl chr 6:137,602,707...137,627,750 		JBrowse link
G Cep63 centrosomal protein 63 increases expression ISO triptolide results in increased expression of CEP63 mRNA CTD PMID:32835833 NCBI chr 8:112,041,586...112,093,061
Ensembl chr 8:112,041,594...112,084,646 		JBrowse link
G Ces1c carboxylesterase 1C increases expression EXP triptolide results in increased expression of CES1C protein CTD PMID:32519852 NCBI chr19:30,099,383...30,128,531
Ensembl chr19:30,099,323...30,128,528 		JBrowse link
G Ces1d carboxylesterase 1D increases expression EXP triptolide results in increased expression of CES1D protein CTD PMID:32519852 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449 		JBrowse link
G Ces4a carboxylesterase 4A decreases expression ISO triptolide results in decreased expression of CES4A mRNA CTD PMID:32835833 NCBI chr19:49,921,643...49,942,838
Ensembl chr19:49,921,608...49,939,461 		JBrowse link
G Cfap20dc CFAP20 domain containing decreases expression ISO triptolide results in decreased expression of CFAP20DC mRNA CTD PMID:32835833 NCBI chr15:18,661,562...18,907,226
Ensembl chr15:18,661,508...18,907,225 		JBrowse link
G Cfb complement factor B decreases expression ISO triptolide results in decreased expression of CFB mRNA CTD PMID:32835833 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740 		JBrowse link
G Cfh complement factor H increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of CFH protein
triptolide results in decreased expression of CFH mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Cfl2 cofilin 2 increases expression EXP triptolide results in increased expression of CFL2 protein CTD PMID:32519852 NCBI chr 6:78,090,843...78,094,888
Ensembl chr 6:78,090,843...78,094,888 		JBrowse link
G Cgas cyclic GMP-AMP synthase increases expression ISO triptolide results in increased expression of CGAS mRNA; triptolide results in increased expression of CGAS protein CTD PMID:36520315 NCBI chr 8:88,172,559...88,187,538
Ensembl chr 8:88,174,512...88,185,859 		JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 increases expression EXP triptolide results in increased expression of CHCHD3 protein CTD PMID:32519852 NCBI chr 4:62,327,574...62,584,085
Ensembl chr 4:62,327,576...62,584,035 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP triptolide results in increased expression of CHCHD6 protein CTD PMID:32519852 NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421 		JBrowse link
G Chka choline kinase alpha increases expression ISO triptolide results in increased expression of CHKA mRNA CTD PMID:32835833 NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit decreases expression ISO triptolide results in decreased expression of CHRNA4 mRNA CTD PMID:32835833 NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105 		JBrowse link
G Ciao3 cytosolic iron-sulfur assembly component 3 increases expression EXP triptolide results in increased expression of NARFL protein CTD PMID:32519852 NCBI chr10:15,300,403...15,309,467
Ensembl chr10:15,300,471...15,309,468 		JBrowse link
G Ciart circadian associated repressor of transcription decreases expression ISO triptolide results in decreased expression of CIART mRNA CTD PMID:32835833 NCBI chr 2:186,108,744...186,113,778
Ensembl chr 2:186,108,752...186,112,246 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression ISO triptolide results in increased expression of CIDEC mRNA CTD PMID:32835833 NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806 		JBrowse link
G Cimap1b ciliary microtubule associated protein 1B decreases expression ISO triptolide results in decreased expression of CIMAP1B mRNA CTD PMID:32835833 NCBI chr 7:122,323,860...122,326,921
Ensembl chr 7:122,323,860...122,326,876 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO triptolide results in increased expression of CKAP2 mRNA CTD PMID:32835833 NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO triptolide results in increased expression of CLCF1 mRNA CTD PMID:32835833 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Clcnkb chloride voltage-gated channel Kb increases expression EXP triptolide results in increased expression of CLCNKB protein CTD PMID:32519852 NCBI chr 5:158,993,073...159,005,618
Ensembl chr 5:158,993,074...159,004,900 		JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of CLDN11 mRNA; triptolide results in decreased expression of CLDN11 protein
mitoquinone inhibits the reaction [triptolide results in decreased expression of CLDN11 mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of CLDN11 protein] 		CTD PMID:30836114 NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539 		JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO triptolide results in increased expression of CLEC11A mRNA CTD PMID:32835833 NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784 		JBrowse link
G Clmn calmin decreases expression ISO triptolide results in decreased expression of CLMN mRNA CTD PMID:32835833 NCBI chr 6:129,470,613...129,572,079
Ensembl chr 6:129,478,149...129,572,027 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X affects expression ISO triptolide affects the expression of CLPX mRNA CTD PMID:32835833 NCBI chr 8:74,700,602...74,740,244
Ensembl chr 8:74,700,662...74,744,762 		JBrowse link
G Clu clusterin increases expression EXP triptolide results in increased expression of CLU protein CTD PMID:32519852 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cluap1 clusterin associated protein 1 increases expression ISO triptolide results in increased expression of CLUAP1 mRNA CTD PMID:32835833 NCBI chr10:12,094,346...12,159,440
Ensembl chr10:12,094,346...12,131,693 		JBrowse link
G Cmah cytidine monophospho-N-acetylneuraminic acid hydroxylase decreases expression ISO triptolide results in decreased expression of CMAH mRNA CTD PMID:32835833 NCBI chr17:40,985,129...41,070,317
Ensembl chr17:41,011,641...41,070,252 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression EXP triptolide results in increased expression of CMPK2 protein CTD PMID:32519852 NCBI chr 6:48,802,150...48,813,652
Ensembl chr 6:48,802,321...48,813,652 		JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression EXP triptolide results in decreased expression of CNBP protein CTD PMID:32519852 NCBI chr 4:121,860,102...121,868,976
Ensembl chr 4:121,860,105...121,869,010 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of CNP protein
triptolide results in decreased expression of CNP mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr10:86,011,504...86,018,063
Ensembl chr10:86,011,495...86,018,063 		JBrowse link
G Cog5 component of oligomeric golgi complex 5 decreases expression EXP triptolide results in decreased expression of COG5 protein CTD PMID:32519852 NCBI chr 6:53,969,967...54,267,869
Ensembl chr 6:53,969,979...54,278,973 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain increases expression ISO triptolide results in increased expression of COL11A2 mRNA CTD PMID:32835833 NCBI chr20:4,788,829...4,818,492
Ensembl chr20:4,788,829...4,817,648 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression ISO triptolide results in increased expression of COL12A1 mRNA CTD PMID:32835833 NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711 		JBrowse link
G Col20a1 collagen type XX alpha 1 chain increases expression ISO triptolide results in increased expression of COL20A1 mRNA CTD PMID:32835833 NCBI chr 3:188,477,663...188,512,326
Ensembl chr 3:188,465,648...188,511,078 		JBrowse link
G Col7a1 collagen type VII alpha 1 chain increases expression ISO triptolide results in increased expression of COL7A1 mRNA CTD PMID:32835833 NCBI chr 8:118,483,364...118,515,736
Ensembl chr 8:118,483,364...118,517,439 		JBrowse link
G Comt catechol-O-methyltransferase decreases expression EXP triptolide results in decreased expression of COMT protein CTD PMID:32519852 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cp ceruloplasmin increases expression EXP triptolide results in increased expression of CP protein CTD PMID:32519852 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression ISO triptolide results in decreased expression of CPS1 mRNA CTD PMID:32835833 NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734 		JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 decreases expression EXP triptolide results in decreased expression of CPSF2 protein CTD PMID:32519852 NCBI chr 6:126,885,417...126,917,634
Ensembl chr 6:126,885,476...126,917,632 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO triptolide results in increased expression of CPT1A mRNA CTD PMID:29723566 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO triptolide results in decreased expression of CPT1B mRNA CTD PMID:31241159 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO triptolide results in decreased expression of CPT2 mRNA CTD PMID:31241159 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818 		JBrowse link
G Crbn cereblon increases expression EXP triptolide results in increased expression of CRBN protein CTD PMID:32519852 NCBI chr 4:141,255,400...141,276,722
Ensembl chr 4:141,257,243...141,276,038 		JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 increases expression ISO triptolide results in increased expression of CREB3L4 mRNA CTD PMID:32835833 NCBI chr 2:177,987,981...177,994,568
Ensembl chr 2:177,987,981...177,993,485 		JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP triptolide results in decreased expression of CREM mRNA CTD PMID:23639586 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crip2 cysteine-rich protein 2 increases expression ISO triptolide results in increased expression of CRIP2 mRNA CTD PMID:32835833 NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein decreases expression
increases expression 		EXP triptolide results in decreased expression of CRK mRNA
triptolide results in increased expression of CRK mRNA 		CTD PMID:23639586 NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988 		JBrowse link
G Crp C-reactive protein increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of CRP protein
triptolide results in decreased expression of CRP mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression ISO triptolide results in increased expression of CRY1 mRNA CTD PMID:32835833 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Cryab crystallin, alpha B increases expression ISO triptolide results in increased expression of CRYAB mRNA CTD PMID:32835833 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 decreases expression ISO triptolide results in decreased expression of CSPG5 mRNA CTD PMID:32835833 NCBI chr 8:119,098,932...119,113,191
Ensembl chr 8:119,098,925...119,143,907 		JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO triptolide results in decreased expression of CTF1 mRNA CTD PMID:32835833 NCBI chr 1:191,758,512...191,771,259
Ensembl chr 1:191,757,477...191,776,395 		JBrowse link
G Ctps1 CTP synthase 1 increases expression ISO triptolide results in increased expression of CTPS1 mRNA CTD PMID:32835833 NCBI chr 5:139,372,349...139,440,441
Ensembl chr 5:139,410,249...139,440,465 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 affects expression ISO triptolide affects the expression of CXCL11 mRNA CTD PMID:32835833 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions 		ISO triptolide results in increased expression of CXCL2 mRNA
IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA] 		CTD PMID:24949944 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases expression 		ISO IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; triptolide inhibits the reaction [Chlorine results in increased expression of CXCL1 protein] CTD PMID:20348278 PMID:24949944 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO triptolide results in decreased expression of CXCR4 protein CTD PMID:26420756 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459 		JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 decreases expression ISO triptolide results in decreased expression of CYB5R3 mRNA CTD PMID:32835833 NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects localization 		ISO
EXP 		TRAJ18 protein affects the reaction [triptolide affects the localization of CYCS protein]
3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [triptolide affects the localization of CYCS protein] 		CTD PMID:31557070 PMID:36520315 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
decreases expression 		EXP
ISO 		triptolide results in decreased expression of and results in decreased activity of CYP11A1 protein
triptolide results in decreased expression of CYP11A1 mRNA
[Colforsin co-treated with triptolide] results in decreased expression of CYP11A1 mRNA 		CTD PMID:22592319 PMID:31557376 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196 		JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP11B1 mRNA CTD PMID:31557376 NCBI chr 7:108,719,349...108,726,024
Ensembl chr 7:108,719,349...108,725,763 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP11B2 mRNA CTD PMID:31557376 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression 		ISO [Colforsin co-treated with triptolide] results in decreased expression of CYP17A1 mRNA
triptolide results in decreased expression of CYP17A1 mRNA 		CTD PMID:31557376 PMID:32835833 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression ISO triptolide affects the expression of CYP26A1 mRNA CTD PMID:32835833 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP27A1 mRNA CTD PMID:32987112 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO triptolide results in increased expression of CYP27B1 mRNA CTD PMID:32835833 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2A1 mRNA] CTD PMID:32987112 NCBI chr 1:91,359,278...91,372,554
Ensembl chr 1:91,359,272...91,389,730 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression ISO triptolide results in decreased expression of CYP2A4 mRNA CTD PMID:32835833 NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression EXP triptolide results in decreased expression of CYP2B1 mRNA CTD PMID:33600922 NCBI chr 1:90,646,098...90,669,762 JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression 		ISO TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP2B10 mRNA] CTD PMID:32835833 PMID:32987112 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP triptolide results in decreased expression of CYP2C11 protein CTD PMID:32519852 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 decreases expression EXP triptolide results in decreased expression of CYP2C23 protein CTD PMID:32519852 NCBI chr 1:252,838,427...252,863,081
Ensembl chr 1:252,838,433...252,863,067 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO triptolide results in decreased expression of CYP2C29 mRNA CTD PMID:32835833 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression EXP triptolide results in decreased expression of CYP2C8 protein CTD PMID:33600922
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 increases expression EXP triptolide results in increased expression of CYP2D26 protein CTD PMID:32519852 NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression ISO triptolide results in increased expression of CYP2E1 mRNA; triptolide results in increased expression of CYP2E1 protein CTD PMID:34758665 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP39A1 mRNA CTD PMID:32835833 NCBI chr 9:24,727,817...24,804,060
Ensembl chr 9:24,727,817...24,804,060 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
decreases expression 		EXP CYP3A2 affects the metabolism of triptolide
triptolide results in decreased expression of CYP3A4 protein 		CTD PMID:20223271 PMID:33600922 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
decreases activity 		EXP triptolide results in decreased expression of CYP3A23-3A1 mRNA
triptolide results in decreased activity of CYP3A23-3A1 protein 		CTD PMID:33600922 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO triptolide results in decreased expression of CYP4F14 mRNA CTD PMID:32835833 NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612 		JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO triptolide results in decreased expression of CYP51 mRNA CTD PMID:32835833 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in decreased expression of CYP7A1 protein; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in decreased expression of CYP7A1 protein]; TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP7A1 mRNA] CTD PMID:32987112 PMID:36328986 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
decreases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in decreased expression of CYP8B1 protein; TRAJ18 protein affects the reaction [triptolide results in decreased expression of CYP8B1 mRNA] CTD PMID:32835833 PMID:32987112 PMID:36328986 NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor decreases expression ISO triptolide results in decreased expression of DBP mRNA CTD PMID:32835833 NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205 		JBrowse link
G Dclk3 doublecortin-like kinase 3 decreases expression ISO triptolide results in decreased expression of DCLK3 mRNA CTD PMID:32835833 NCBI chr 8:120,279,916...120,332,362
Ensembl chr 8:120,279,757...120,332,432 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression ISO triptolide results in increased expression of DDIAS mRNA CTD PMID:32835833 NCBI chr 1:156,318,559...156,342,869
Ensembl chr 1:156,318,563...156,342,869 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions 		ISO triptolide results in increased expression of DDIT3 mRNA; triptolide results in increased expression of DDIT3 protein
STING1 protein affects the reaction [triptolide results in increased expression of DDIT3 mRNA]; STING1 protein affects the reaction [triptolide results in increased expression of DDIT3 protein]; TRAJ18 protein affects the reaction [triptolide results in increased expression of DDIT3 mRNA] 		CTD PMID:26990902 PMID:27022166 PMID:36520315 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression ISO triptolide results in increased expression of DDIT4L mRNA CTD PMID:32835833 NCBI chr 2:228,800,831...228,804,478
Ensembl chr 2:228,801,705...228,806,225 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 decreases expression EXP triptolide results in decreased expression of DDRGK1 protein CTD PMID:32519852 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:138,315,282...138,335,766 		JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO triptolide results in increased expression of DDX17 mRNA CTD PMID:32835833 NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747 		JBrowse link
G Defb1 defensin beta 1 decreases expression ISO triptolide results in decreased expression of DEFB1 mRNA CTD PMID:32835833 NCBI chr16:77,001,326...77,016,068
Ensembl chr16:77,001,326...77,016,068 		JBrowse link
G Dennd1a DENN domain containing 1A increases expression EXP triptolide results in increased expression of DENND1A protein CTD PMID:32519852 NCBI chr 3:41,974,502...42,461,816
Ensembl chr 3:41,974,502...42,461,886 		JBrowse link
G Depp1 DEPP autophagy regulator 1 decreases expression ISO triptolide results in decreased expression of DEPP1 mRNA CTD PMID:32835833 NCBI chr 4:151,583,105...151,585,455
Ensembl chr 4:151,581,502...151,586,233 		JBrowse link
G Des desmin multiple interactions EXP triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein] CTD PMID:18509322 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347 		JBrowse link
G Dglucy D-glutamate cyclase decreases expression EXP triptolide results in decreased expression of DGLUCY protein CTD PMID:32519852 NCBI chr 6:125,785,075...125,860,496
Ensembl chr 6:125,785,087...125,860,496 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO triptolide results in decreased expression of DHCR7 mRNA CTD PMID:32835833 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO triptolide results in decreased expression of DHRS7 mRNA CTD PMID:32835833 NCBI chr 6:97,068,149...97,083,744
Ensembl chr 6:97,068,149...97,083,744 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B increases expression EXP triptolide results in increased expression of DHRS7B protein CTD PMID:32519852 NCBI chr10:46,003,845...46,036,498
Ensembl chr10:46,003,845...46,036,499 		JBrowse link
G Dhrs7l1 dehydrogenase/reductase (SDR family) member 7-like 1 decreases expression EXP triptolide results in decreased expression of DHRS7L1 protein CTD PMID:32519852 NCBI chr 6:97,025,094...97,047,899
Ensembl chr 6:97,025,094...97,047,899 		JBrowse link
G Dhx29 DExH-box helicase 29 increases expression ISO triptolide results in increased expression of DHX29 mRNA CTD PMID:32835833 NCBI chr 2:46,293,901...46,344,652
Ensembl chr 2:46,293,677...46,344,948 		JBrowse link
G Dhx37 DEAH-box helicase 37 increases expression ISO triptolide results in increased expression of DHX37 mRNA CTD PMID:32835833 NCBI chr12:36,856,119...36,876,245
Ensembl chr12:36,849,701...36,876,240 		JBrowse link
G Dhx38 DEAH-box helicase 38 increases expression ISO triptolide results in increased expression of DHX38 mRNA CTD PMID:32835833 NCBI chr19:54,422,418...54,439,434
Ensembl chr19:54,422,418...54,439,423 		JBrowse link
G Dhx58 DEXH-box helicase 58 increases expression EXP triptolide results in increased expression of DHX58 protein CTD PMID:32519852 NCBI chr10:86,120,677...86,132,095
Ensembl chr10:86,120,677...86,131,844 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO triptolide results in decreased expression of DIO1 mRNA CTD PMID:32835833 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Dixdc1 DIX domain containing 1 decreases expression ISO triptolide results in decreased expression of DIXDC1 mRNA CTD PMID:32835833 NCBI chr 8:59,904,218...59,977,595
Ensembl chr 8:59,904,218...59,978,447 		JBrowse link
G Dnah10 dynein, axonemal, heavy chain 10 increases expression ISO triptolide results in increased expression of DNAH10 mRNA CTD PMID:32835833 NCBI chr12:37,484,444...37,607,810
Ensembl chr12:37,472,813...37,640,860 		JBrowse link
G Dnah5 dynein, axonemal, heavy chain 5 increases expression ISO triptolide results in increased expression of DNAH5 mRNA CTD PMID:32835833 NCBI chr 2:80,668,182...80,985,918
Ensembl chr 2:80,668,208...80,985,914 		JBrowse link
G Dnai7 dynein axonemal intermediate chain 7 increases expression ISO triptolide results in increased expression of DNAI7 mRNA CTD PMID:32835833 NCBI chr 4:179,874,338...179,910,716
Ensembl chr 4:179,873,522...179,910,780 		JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression EXP triptolide results in increased expression of DNAJB12 protein CTD PMID:32519852 NCBI chr20:28,371,180...28,389,390
Ensembl chr20:28,371,199...28,389,389 		JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 decreases expression EXP triptolide results in decreased expression of DNAJC6 protein CTD PMID:32519852 NCBI chr 5:121,232,532...121,398,775
Ensembl chr 5:121,235,425...121,398,775 		JBrowse link
G Dnhd1 dynein heavy chain domain 1 increases expression ISO triptolide results in increased expression of DNHD1 mRNA CTD PMID:32835833 NCBI chr 1:169,402,615...169,486,684
Ensembl chr 1:169,394,884...169,487,646 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions
decreases expression
increases expression 		ISO
EXP 		mitoquinone inhibits the reaction [triptolide results in decreased expression of DNM1L protein]
triptolide results in increased expression of DRP1 protein
3-(2,4-dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone inhibits the reaction [triptolide results in increased expression of DRP1 protein] 		CTD PMID:30836114 PMID:31557070 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420 		JBrowse link
G Dpep1 dipeptidase 1 increases expression EXP triptolide results in increased expression of DPEP1 protein CTD PMID:32519852 NCBI chr19:68,118,270...68,143,781
Ensembl chr19:68,118,453...68,143,775 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP triptolide affects the expression of DPP4 protein CTD PMID:32519852 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 decreases expression EXP triptolide results in decreased expression of DTNBP1 protein CTD PMID:32519852 NCBI chr17:19,891,313...19,982,770
Ensembl chr17:19,891,337...19,984,418 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 increases expression ISO triptolide results in increased expression of DTX4 mRNA CTD PMID:32835833 NCBI chr 1:218,882,391...218,969,837
Ensembl chr 1:218,832,284...218,917,130 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression ISO triptolide results in decreased expression of DUSP1 protein CTD PMID:17507666 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 increases expression EXP triptolide results in increased expression of DYNC2H1 protein CTD PMID:32519852 NCBI chr 8:12,473,955...12,697,075
Ensembl chr 8:12,473,955...12,697,058 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 increases expression ISO triptolide results in increased expression of DYNLL1 mRNA CTD PMID:32835833 NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861 		JBrowse link
G E2f1 E2F transcription factor 1 increases expression EXP triptolide results in increased expression of E2F1 mRNA CTD PMID:23639586 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G E2f3 E2F transcription factor 3 increases expression EXP triptolide results in increased expression of E2F3 mRNA CTD PMID:23639586 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725 		JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial increases expression ISO triptolide results in increased expression of EARS2 mRNA CTD PMID:32835833 NCBI chr 1:186,025,740...186,057,165 JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO triptolide results in decreased expression of ECHDC1 mRNA CTD PMID:32835833 NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208 		JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression EXP triptolide results in decreased expression of ECHDC2 protein CTD PMID:32519852 NCBI chr 5:128,144,241...128,163,611
Ensembl chr 5:128,144,425...128,163,610 		JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO triptolide results in increased expression of EDA2R mRNA CTD PMID:32835833 NCBI chr  X:66,225,557...66,280,674
Ensembl chr  X:66,236,111...66,280,663 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression ISO triptolide results in increased expression of EEF1E1 mRNA CTD PMID:32835833 NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687 		JBrowse link
G Efnb3 ephrin B3 increases expression ISO triptolide results in increased expression of EFNB3 mRNA CTD PMID:32835833 NCBI chr10:54,773,282...54,780,727
Ensembl chr10:54,773,282...54,797,651 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO triptolide results in decreased expression of EGFR mRNA CTD PMID:32835833 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Ehd2 EH-domain containing 2 increases expression EXP triptolide results in increased expression of EHD2 protein CTD PMID:32519852 NCBI chr 1:85,767,757...85,786,974
Ensembl chr 1:85,768,667...85,786,943 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO triptolide results in increased expression of EHHADH mRNA CTD PMID:29723566 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:92,746,420...92,779,662 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases expression EXP triptolide results in increased expression of EIF2AK2 protein CTD PMID:32519852 NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:21,952,631...21,977,116 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO triptolide results in increased phosphorylation of EIF2AK3 protein CTD PMID:27022166 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta increases expression EXP triptolide results in increased expression of EIF2B4 protein CTD PMID:32519852 NCBI chr 6:30,903,148...30,908,803
Ensembl chr 6:30,903,219...30,908,800 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha affects phosphorylation
multiple interactions 		ISO triptolide affects the phosphorylation of EIF2S1 protein
TRAJ18 protein affects the reaction [triptolide affects the phosphorylation of EIF2S1 protein] 		CTD PMID:36520315 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression ISO triptolide results in increased expression of EIF4E mRNA CTD PMID:32835833 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105 		JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 decreases expression ISO triptolide results in decreased expression of EIF4EBP3 mRNA CTD PMID:32835833 NCBI chr18:28,540,324...28,542,070
Ensembl chr18:28,540,058...28,542,061 		JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 increases expression EXP triptolide results in increased expression of EIPR1 protein CTD PMID:32519852 NCBI chr 6:51,116,827...51,230,453
Ensembl chr 6:51,116,747...51,230,452 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO triptolide results in increased expression of ELF3 mRNA CTD PMID:32835833 NCBI chr13:49,242,265...49,247,102
Ensembl chr13:49,242,267...49,247,380 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 decreases expression ISO triptolide results in decreased expression of ELOVL2 mRNA CTD PMID:32835833 NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression ISO triptolide results in decreased expression of ELOVL5 mRNA CTD PMID:32835833 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression ISO triptolide results in decreased expression of ELOVL6 mRNA CTD PMID:32835833 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549 		JBrowse link
G Emc3 ER membrane protein complex subunit 3 increases expression EXP triptolide results in increased expression of EMC3 protein CTD PMID:32519852 NCBI chr 4:148,218,686...148,234,595
Ensembl chr 4:148,217,395...148,234,595 		JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP triptolide results in increased expression of EMC8 protein CTD PMID:32519852 NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 increases expression ISO triptolide results in increased expression of EME2 mRNA CTD PMID:32835833 NCBI chr10:14,413,661...14,420,489
Ensembl chr10:14,417,735...14,420,489 		JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression ISO triptolide results in increased expression of ENC1 mRNA CTD PMID:32835833 NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721 		JBrowse link
G Endod1 endonuclease domain containing 1 increases expression ISO triptolide results in increased expression of ENDOD1 mRNA CTD PMID:32835833 NCBI chr 8:19,490,615...19,520,007
Ensembl chr 8:19,490,615...19,520,007 		JBrowse link
G Endog endonuclease G increases expression ISO triptolide results in increased expression of ENDOG protein CTD PMID:26990902 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573 		JBrowse link
G Eno3 enolase 3 increases expression ISO triptolide results in increased expression of ENO3 mRNA CTD PMID:32835833 NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,866,101...55,874,540 		JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP triptolide affects the expression of ENPEP protein CTD PMID:32519852 NCBI chr 2:220,456,258...220,526,218
Ensembl chr 2:220,456,278...220,526,218 		JBrowse link
G Erlin1 ER lipid raft associated 1 increases expression EXP triptolide results in increased expression of ERLIN1 protein CTD PMID:32519852 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947 		JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression EXP triptolide results in increased expression of ERMP1 protein CTD PMID:32519852 NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression EXP triptolide results in increased expression of ESPL1 mRNA CTD PMID:23639586 NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570 		JBrowse link
G Esrrb estrogen-related receptor beta increases expression EXP triptolide results in increased expression of ESRRB protein CTD PMID:32519852 NCBI chr 6:111,738,662...111,894,087
Ensembl chr 6:111,738,662...111,894,087 		JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO triptolide results in increased expression of EXOC4 mRNA CTD PMID:32835833 NCBI chr 4:62,774,896...63,551,541
Ensembl chr 4:62,774,935...63,552,943 		JBrowse link
G Exosc9 exosome component 9 increases expression ISO triptolide results in increased expression of EXOSC9 mRNA CTD PMID:32835833 NCBI chr 2:121,344,154...121,355,110
Ensembl chr 2:121,344,175...121,374,232 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO triptolide results in decreased expression of EZH2 protein CTD PMID:19879315 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:77,624,223...77,687,183 		JBrowse link
G F11 coagulation factor XI decreases expression ISO triptolide results in decreased expression of F11 mRNA CTD PMID:32835833 NCBI chr16:53,720,502...53,741,547
Ensembl chr16:53,718,621...53,740,941 		JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression ISO triptolide results in increased expression of F2RL3 mRNA CTD PMID:32835833 NCBI chr16:17,151,516...17,153,509
Ensembl chr16:17,151,516...17,153,823 		JBrowse link
G F5 coagulation factor V increases expression EXP triptolide results in increased expression of F5 protein CTD PMID:32519852 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:79,046,448...79,116,247 		JBrowse link
G F9 coagulation factor IX increases expression EXP triptolide results in increased expression of F9 protein CTD PMID:32519852 NCBI chr  X:143,388,642...143,433,143
Ensembl chr  X:143,388,621...143,433,146 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO triptolide results in decreased expression of FABP1 mRNA CTD PMID:32835833 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:104,744,309...104,753,113 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP triptolide results in increased expression of FABP4 protein CTD PMID:32519852 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO triptolide results in decreased expression of FABP5 mRNA CTD PMID:32835833 NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression ISO triptolide results in decreased expression of FADS1 mRNA CTD PMID:32835833 NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO triptolide results in decreased expression of FADS2 mRNA CTD PMID:32835833 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO triptolide results in decreased expression of FAM107A mRNA CTD PMID:32835833 NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219 		JBrowse link
G Fam161b FAM161 centrosomal protein B increases expression ISO triptolide results in increased expression of FAM161B mRNA CTD PMID:32835833 NCBI chr 6:109,722,073...109,750,003
Ensembl chr 6:109,722,569...109,750,036 		JBrowse link
G Fam210b family with sequence similarity 210, member B increases expression EXP triptolide results in increased expression of FAM210B protein CTD PMID:32519852 NCBI chr 3:181,536,665...181,546,830
Ensembl chr 3:181,536,673...181,546,834 		JBrowse link
G Fam47e family with sequence similarity 47, member E decreases expression ISO triptolide results in decreased expression of FAM47E mRNA CTD PMID:32835833 NCBI chr14:15,769,441...15,805,911
Ensembl chr14:15,769,050...15,806,061 		JBrowse link
G Fam83h family with sequence similarity 83, member H increases expression ISO triptolide results in increased expression of FAM83H mRNA CTD PMID:32835833 NCBI chr 7:109,597,129...109,605,317
Ensembl chr 7:109,597,129...109,609,188 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO triptolide results in increased expression of FAS protein CTD PMID:26990902 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression 		ISO [triptolide co-treated with FASL protein] results in decreased expression of MIR137; [triptolide co-treated with FASL protein] results in decreased expression of XIAP mRNA; [triptolide co-treated with FASL protein] results in decreased expression of XIAP protein; [triptolide co-treated with FASL protein] results in increased expression of ALPL protein; [triptolide co-treated with FASL protein] results in increased expression of GOT1 protein; [triptolide co-treated with FASL protein] results in increased expression of GPT protein; [triptolide co-treated with FASL protein] results in increased expression of MIR137; [triptolide co-treated with FASL protein] results in increased expression of XIAP mRNA; CASP3 inhibits the reaction [[triptolide co-treated with FASL protein] results in increased cleavage of XIAP protein]; FASL protein promotes the reaction [triptolide results in decreased expression of BCL2 protein]; FASL protein promotes the reaction [triptolide results in decreased expression of FLIP protein]; FASL protein promotes the reaction [triptolide results in increased cleavage of and results in increased activity of CASP3 protein]; IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]; MIR137 promotes the reaction [[triptolide co-treated with FASL protein] results in decreased expression of XIAP protein]
triptolide results in increased expression of FASL mRNA; triptolide results in increased expression of FASL protein 		CTD PMID:24949944 PMID:26990902 PMID:37944651 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO triptolide results in decreased expression of FASN mRNA CTD PMID:32835833 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fbn2 fibrillin 2 decreases expression EXP triptolide results in decreased expression of FBN2 protein CTD PMID:32519852 NCBI chr18:53,696,197...53,901,992
Ensembl chr18:53,697,708...53,902,191 		JBrowse link
G Fbp2 fructose-bisphosphatase 2 decreases expression EXP triptolide results in decreased expression of FBP2 mRNA CTD PMID:23639586 NCBI chr17:2,241,767...2,259,371
Ensembl chr17:2,241,975...2,259,366 		JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 increases expression EXP triptolide results in increased expression of FBXL4 protein CTD PMID:32519852 NCBI chr 5:40,752,513...40,826,154
Ensembl chr 5:40,752,521...40,850,826 		JBrowse link
G Fbxo7 F-box protein 7 increases expression EXP triptolide results in increased expression of FBXO7 protein CTD PMID:32519852 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP triptolide results in increased expression of FDFT1 protein CTD PMID:32519852 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:41,588,117...41,616,168 		JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO triptolide results in decreased expression of FDPS mRNA CTD PMID:32835833 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136 		JBrowse link
G Fetub fetuin B increases expression EXP triptolide results in increased expression of FETUB protein CTD PMID:32519852 NCBI chr11:91,586,750...91,599,789
Ensembl chr11:91,586,748...91,599,310 		JBrowse link
G Ffar4 free fatty acid receptor 4 increases expression ISO triptolide results in increased expression of FFAR4 mRNA CTD PMID:32835833 NCBI chr 1:245,286,009...245,304,029
Ensembl chr 1:245,285,883...245,304,031 		JBrowse link
G Fga fibrinogen alpha chain increases expression EXP triptolide results in increased expression of FGA protein CTD PMID:32519852 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain increases expression EXP triptolide results in increased expression of FGB protein CTD PMID:32519852 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression EXP triptolide results in decreased expression of FGF1 protein CTD PMID:32519852 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 decreases expression ISO triptolide results in decreased expression of FGFRL1 mRNA CTD PMID:32835833 NCBI chr14:1,154,275...1,166,334
Ensembl chr14:1,154,275...1,166,752 		JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP triptolide results in increased expression of FGG protein CTD PMID:32519852 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fjx1 four-jointed box kinase 1 increases expression EXP triptolide results in increased expression of FJX1 protein CTD PMID:32519852 NCBI chr 3:109,229,223...109,231,324
Ensembl chr 3:109,227,170...109,232,479 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO triptolide results in decreased expression of FKBP11 mRNA CTD PMID:32835833 NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO triptolide results in decreased expression of FKBP5 mRNA CTD PMID:32835833 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118 		JBrowse link
G Fmn1 formin 1 decreases expression ISO triptolide results in decreased expression of FMN1 mRNA CTD PMID:32835833 NCBI chr 3:120,555,445...120,939,978
Ensembl chr 3:120,555,431...120,933,124 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 affects expression EXP triptolide affects the expression of FMO5 protein CTD PMID:32519852 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464 		JBrowse link
G Fnip2 folliculin interacting protein 2 decreases expression ISO triptolide results in decreased expression of FNIP2 mRNA CTD PMID:32835833 NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:166,897,075...167,006,055 		JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO triptolide results in decreased phosphorylation of FOXO3 protein CTD PMID:32061799 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO triptolide results in decreased expression of FOXP3 mRNA CTD PMID:24949944 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO triptolide results in decreased expression of FRMD4B mRNA CTD PMID:32835833 NCBI chr 4:131,452,361...131,778,734
Ensembl chr 4:131,452,365...131,640,287 		JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP triptolide results in increased expression of FTH1 protein CTD PMID:32519852 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP triptolide results in increased expression of FTL1 protein CTD PMID:32519852 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915 		JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO triptolide results in increased expression of FUBP1 mRNA CTD PMID:32835833 NCBI chr 2:243,819,529...243,846,544
Ensembl chr 2:243,819,218...243,846,428 		JBrowse link
G Fundc2 FUN14 domain containing 2 decreases expression EXP triptolide results in decreased expression of FUNDC2 protein CTD PMID:32519852 NCBI chr18:142,829...155,123
Ensembl chr18:142,640...155,674 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases expression 		EXP Lithium Chloride inhibits the reaction [triptolide results in increased expression of FYN protein] CTD PMID:30926361 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression
multiple interactions 		EXP
ISO 		triptolide results in decreased expression of G6PC1 mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of G6PC1 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of G6PC1 mRNA] 		CTD PMID:23639586 PMID:30633930 PMID:32835833 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO triptolide results in increased expression of G6PDX mRNA CTD PMID:32835833 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gaa alpha glucosidase increases expression EXP triptolide results in increased expression of GAA protein CTD PMID:32519852 NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases expression ISO triptolide results in decreased expression of GABBR2 mRNA CTD PMID:32835833 NCBI chr 5:65,743,073...66,083,695
Ensembl chr 5:65,743,073...66,083,695 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO triptolide results in increased expression of GADD45B mRNA CTD PMID:32835833 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP triptolide results in decreased expression of GADD45G mRNA CTD PMID:23639586 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO triptolide results in decreased expression of GAL3ST1 mRNA CTD PMID:32835833 NCBI chr14:83,094,265...83,109,992
Ensembl chr14:83,094,385...83,109,978 		JBrowse link
G Galk1 galactokinase 1 decreases expression ISO triptolide results in decreased expression of GALK1 mRNA CTD PMID:32835833 NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258 		JBrowse link
G Galm galactose mutarotase decreases expression EXP triptolide results in decreased expression of GALM mRNA CTD PMID:23639586 NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417 		JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 increases expression EXP triptolide results in increased expression of GALNT11 protein CTD PMID:32519852 NCBI chr 4:10,571,464...10,604,974
Ensembl chr 4:10,571,464...10,604,974 		JBrowse link
G Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 increases expression EXP triptolide results in increased expression of GALNT3 protein CTD PMID:32519852 NCBI chr 3:71,150,559...71,187,321
Ensembl chr 3:71,150,571...71,174,323 		JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP triptolide results in increased expression of GALNT7 protein CTD PMID:32519852 NCBI chr16:37,589,368...37,713,911
Ensembl chr16:37,589,425...37,713,909 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO triptolide results in decreased expression of GAMT mRNA CTD PMID:32835833 NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083 		JBrowse link
G Garin5a golgi associated RAB2 interactor 5A increases expression ISO triptolide results in increased expression of GARIN5A mRNA CTD PMID:32835833 NCBI chr 1:104,125,477...104,130,543
Ensembl chr 1:104,125,160...104,135,840 		JBrowse link
G Gas1 growth arrest-specific 1 decreases expression ISO triptolide results in decreased expression of GAS1 mRNA CTD PMID:32835833 NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657 		JBrowse link
G Gas2l1 growth arrest-specific 2 like 1 increases expression ISO triptolide results in increased expression of GAS2L1 mRNA CTD PMID:32835833 NCBI chr14:84,169,398...84,175,514
Ensembl chr14:84,169,398...84,175,514 		JBrowse link
G Gask1a golgi associated kinase 1A decreases expression ISO triptolide results in decreased expression of FAM198A mRNA CTD PMID:32835833 NCBI chr 8:130,488,279...130,521,242
Ensembl chr 8:130,488,354...130,521,242 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression ISO triptolide results in decreased expression of GBE1 mRNA CTD PMID:32835833 NCBI chr11:22,181,194...22,446,640
Ensembl chr11:22,181,103...22,446,638 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP triptolide results in increased expression of GBP2 protein CTD PMID:32519852 NCBI chr 2:234,005,727...234,021,812
Ensembl chr 2:234,008,590...234,021,810 		JBrowse link
G Gck glucokinase decreases expression EXP triptolide results in decreased expression of GCK mRNA CTD PMID:23639586 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression
multiple interactions 		ISO
EXP 		triptolide results in decreased expression of GCLC protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of GCLC protein] 		CTD PMID:25169008 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gdf9 growth differentiation factor 9 increases expression ISO triptolide results in increased expression of GDF9 mRNA CTD PMID:32835833 NCBI chr10:38,090,021...38,100,801
Ensembl chr10:38,089,878...38,100,797 		JBrowse link
G Gimap4 GTPase, IMAP family member 4 increases expression EXP triptolide results in increased expression of GIMAP4 protein CTD PMID:32519852 NCBI chr 4:78,967,297...78,974,211
Ensembl chr 4:78,967,297...78,974,202 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression
multiple interactions 		ISO
EXP 		triptolide results in decreased expression of GJA1 mRNA; triptolide results in decreased expression of GJA1 protein
mitoquinone inhibits the reaction [triptolide results in decreased expression of GJA1 mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of GJA1 protein] 		CTD PMID:20020930 PMID:30836114 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Glmp glycosylated lysosomal membrane protein decreases expression EXP triptolide results in decreased expression of GLMP protein CTD PMID:32519852 NCBI chr 2:176,092,098...176,095,688
Ensembl chr 2:176,091,839...176,097,208 		JBrowse link
G Gls glutaminase increases expression ISO triptolide results in increased expression of GLS mRNA CTD PMID:32835833 NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase increases expression EXP triptolide results in increased expression of GMDS protein CTD PMID:32519852 NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,304,056...32,830,706 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO triptolide results in decreased expression of GNMT mRNA CTD PMID:32835833 NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692 		JBrowse link
G Gon4l gon-4 like increases expression ISO triptolide results in increased expression of GON4L mRNA CTD PMID:32835833 NCBI chr 2:176,531,274...176,604,446
Ensembl chr 2:176,531,274...176,604,444 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of GOT1 mRNA
[triptolide co-treated with FASL protein] results in increased expression of GOT1 protein 		CTD PMID:32835833 PMID:37944651 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gp5 glycoprotein V (platelet) increases expression ISO triptolide results in increased expression of GP5 mRNA CTD PMID:32835833 NCBI chr11:83,948,507...83,952,362
Ensembl chr11:83,948,507...83,952,367 		JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 increases expression EXP triptolide results in increased expression of GPAA1 protein CTD PMID:32519852 NCBI chr 7:109,932,556...109,936,139
Ensembl chr 7:109,932,544...109,936,138 		JBrowse link
G Gpkow G patch domain and KOW motifs increases expression ISO triptolide results in increased expression of GPKOW mRNA CTD PMID:32835833 NCBI chr  X:17,463,521...17,478,298
Ensembl chr  X:17,463,525...17,478,298 		JBrowse link
G Gpr12 G protein-coupled receptor 12 decreases expression ISO triptolide results in decreased expression of GPR12 mRNA CTD PMID:32835833 NCBI chr12:13,636,549...13,640,083
Ensembl chr12:13,627,055...13,643,650 		JBrowse link
G Gpr146 G protein-coupled receptor 146 decreases expression ISO triptolide results in decreased expression of GPR146 mRNA CTD PMID:32835833 NCBI chr12:20,365,790...20,381,122
Ensembl chr12:20,364,269...20,381,345 		JBrowse link
G Gprasp3 G protein-coupled receptor associated sorting protein family member 3 decreases expression ISO triptolide results in decreased expression of BHLHB9 mRNA CTD PMID:32835833 NCBI chr  X:103,639,366...103,644,561
Ensembl chr  X:103,609,243...103,650,463 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
increases expression 		ISO
EXP 		triptolide results in increased activity of GPT protein
4-phenylbutyric acid inhibits the reaction [triptolide results in increased expression of GPT protein]; [triptolide co-treated with FASL protein] results in increased expression of GPT protein; [triptolide co-treated with Lipopolysaccharides] results in increased expression of GPT protein; ABCB1A mutant form promotes the reaction [triptolide results in increased activity of GPT protein]; Chlormethiazole inhibits the reaction [triptolide results in increased activity of GPT protein]; IL12B protein affects the reaction [triptolide results in increased expression of GPT protein]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; pyrazole promotes the reaction [triptolide results in increased activity of GPT protein]; STING1 protein affects the reaction [triptolide results in increased expression of GPT protein]; TRAJ18 protein affects the reaction [triptolide results in increased expression of GPT protein]
catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]; catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]; Chlormethiazole inhibits the reaction [triptolide results in increased activity of GPT protein]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [triptolide results in increased expression of GPT protein]; pyrazole promotes the reaction [triptolide results in increased activity of GPT protein]; Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]
[Atorvastatin co-treated with triptolide] results in increased expression of GPT protein 		CTD PMID:23836259 PMID:26134275 PMID:30682494 PMID:32987112 PMID:33600922 More... NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression 		ISO
EXP 		Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA]
triptolide results in increased expression of GPX1 protein 		CTD PMID:31241159 PMID:32519852 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions
increases expression 		ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] CTD PMID:31241159 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions
increases expression 		ISO Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] CTD PMID:31241159 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions
decreases expression 		ISO triptolide results in increased expression of GPX4 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of GPX4 protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA]; ferrostatin-1 inhibits the reaction [triptolide results in decreased expression of GPX4 protein]; GPX4 protein inhibits the reaction [triptolide results in increased expression of H2AX protein]; triptolide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of GPX4 protein]; triptolide promotes the reaction [Cycloheximide results in decreased expression of GPX4 protein] 		CTD PMID:31241159 PMID:38960301 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO triptolide results in decreased expression of GRB2 protein CTD PMID:26420756 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO triptolide results in decreased expression of GREM2 mRNA CTD PMID:32835833 NCBI chr13:89,310,897...89,403,856
Ensembl chr13:89,310,662...89,404,312 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 increases expression ISO triptolide results in increased expression of GRHL1 mRNA CTD PMID:32835833 NCBI chr 6:46,935,947...46,986,126
Ensembl chr 6:46,935,967...46,980,264 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO triptolide results in increased expression of GRIK5 mRNA CTD PMID:32835833 NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:89,733,741...89,794,962 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression ISO triptolide results in increased expression of GRWD1 mRNA CTD PMID:32835833 NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825 		JBrowse link
G Gsdmd gasdermin D increases expression
multiple interactions 		EXP
ISO 		triptolide results in increased expression of GSDMD protein
[triptolide co-treated with Lipopolysaccharides] results in increased cleavage of GSDMD protein; [triptolide co-treated with TNF protein] results in increased cleavage of GSDMD protein; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased cleavage of GSDMD protein]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased cleavage of GSDMD protein] 		CTD PMID:32519852 PMID:36328986 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation 		EXP Lithium Chloride inhibits the reaction [triptolide results in increased phosphorylation of GSK3B protein] CTD PMID:30926361 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 increases expression ISO triptolide results in increased expression of GTF2F1 mRNA CTD PMID:32835833 NCBI chr 9:1,931,033...1,940,197
Ensembl chr 9:1,930,055...1,940,197 		JBrowse link
G Gtpbp4 GTP binding protein 4 increases expression ISO triptolide results in increased expression of GTPBP4 mRNA CTD PMID:32835833 NCBI chr17:65,997,472...66,019,530
Ensembl chr17:66,276,566...66,289,637 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO triptolide results in increased expression of GTSE1 mRNA CTD PMID:32835833 NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661 		JBrowse link
G Gusb glucuronidase, beta multiple interactions
decreases activity 		ISO resveratrol inhibits the reaction [triptolide results in decreased activity of GUSB protein] CTD PMID:29723566 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G Gys2 glycogen synthase 2 decreases expression ISO triptolide results in decreased expression of GYS2 mRNA CTD PMID:32835833 NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:177,096,063...177,137,236 		JBrowse link
G H1f10 H1.10 linker histone increases expression ISO triptolide results in increased expression of H1F10 mRNA CTD PMID:32835833 NCBI chr 4:121,997,834...121,998,897
Ensembl chr 4:121,997,831...121,998,966 		JBrowse link
G H1f4 H1.4 linker histone, cluster member increases expression ISO triptolide results in increased expression of H1F4 mRNA CTD PMID:32835833 NCBI chr17:41,914,425...41,915,206
Ensembl chr17:41,914,431...41,916,129 		JBrowse link
G H2ac4 H2A clustered histone 4 increases expression ISO triptolide results in increased expression of H2AC6 mRNA CTD PMID:32835833 NCBI chr17:47,495,624...47,496,127
Ensembl chr17:47,495,546...47,496,173 		JBrowse link
G H2aj H2A.J histone increases expression ISO triptolide results in increased expression of H2AJ mRNA CTD PMID:32835833 NCBI chr 4:171,406,922...171,407,406
Ensembl chr 4:171,406,177...171,408,845 		JBrowse link
G H2ax H2A.X variant histone increases expression
increases phosphorylation
multiple interactions 		ISO triptolide results in increased expression of H2AX mRNA; triptolide results in increased expression of H2AX protein
triptolide results in increased phosphorylation of H2AX protein
ferrostatin-1 inhibits the reaction [triptolide results in increased expression of H2AX protein]; GPX4 protein inhibits the reaction [triptolide results in increased expression of H2AX protein] 		CTD PMID:31218727 PMID:32835833 PMID:36990132 PMID:38960301 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G H2az1 H2A.Z variant histone 1 decreases expression EXP triptolide results in decreased expression of H2AZ1 protein CTD PMID:32519852 NCBI chr 2:229,026,464...229,031,411
Ensembl chr 2:229,028,843...229,031,411 		JBrowse link
G H2bc6 H2B clustered histone 6 increases expression ISO triptolide results in increased expression of H2BC6 mRNA CTD PMID:32835833 NCBI chr17:41,948,813...41,949,276
Ensembl chr17:47,392,229...47,449,312 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO triptolide results in decreased expression of HAAO mRNA CTD PMID:32835833 NCBI chr 6:16,598,325...16,617,590
Ensembl chr 6:16,598,087...16,617,356 		JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression ISO triptolide results in decreased expression of HAO1 mRNA CTD PMID:32835833 NCBI chr 3:142,102,873...142,281,527
Ensembl chr 3:142,224,612...142,281,494 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 increases expression EXP triptolide results in increased expression of HBA-A2 protein; triptolide results in increased expression of HBA1 protein CTD PMID:32519852 NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141 		JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP triptolide results in increased expression of HBB protein CTD PMID:32519852 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873 		JBrowse link
G Hdac1 histone deacetylase 1 increases expression EXP triptolide results in increased expression of HDAC1 mRNA CTD PMID:23639586 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:147,138,156...147,165,387 		JBrowse link
G Hdac1l histone deacetylase 1-like increases expression EXP triptolide results in increased expression of HDAC1L protein CTD PMID:32519852 NCBI chr 9:87,901,045...87,903,045
Ensembl chr 9:87,896,472...87,903,613 		JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP triptolide results in increased expression of HDAC2 protein CTD PMID:32519852 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hdac6 histone deacetylase 6 increases expression ISO triptolide results in increased expression of HDAC6 mRNA; triptolide results in increased expression of HDAC6 protein CTD PMID:32061799 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 increases expression EXP triptolide results in increased expression of HERC6 protein CTD PMID:32519852 NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO triptolide results in decreased expression of HERPUD1 mRNA CTD PMID:32835833 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
multiple interactions
increases expression 		ISO triptolide results in decreased expression of HES1 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of HES1 protein]
triptolide results in decreased expression of HES1 mRNA; triptolide results in decreased expression of HES1 protein 		CTD PMID:30394310 PMID:31241159 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO triptolide results in decreased expression of HES6 mRNA CTD PMID:32835833 NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO triptolide results in increased expression of HEXIM1 mRNA CTD PMID:32835833 NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,560,519...88,580,000 		JBrowse link
G Higd2al1 HIG1 hypoxia inducible domain family, member 2A-like 1 increases expression EXP triptolide results in increased expression of HIGD2AL1 protein CTD PMID:32519852 NCBI chr12:7,574,795...7,575,432
Ensembl chr12:7,574,944...7,575,425 		JBrowse link
G Hikeshi heat shock protein nuclear import factor hikeshi increases expression EXP triptolide results in increased expression of HIKESHI protein CTD PMID:32519852 NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911 		JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO triptolide results in increased expression of H3C11 mRNA; triptolide results in increased expression of H3C6 mRNA CTD PMID:32835833 NCBI chr17:41,996,216...41,997,128
Ensembl chr17:47,493,820...47,494,861
Ensembl chr17:47,493,820...47,494,861 		JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO triptolide results in increased expression of H2BC21 mRNA CTD PMID:32835833 NCBI chr17:47,388,085...47,392,349
Ensembl chr17:47,404,375...47,419,020 		JBrowse link
G Hist1h4b histone cluster 1 H4 family member B increases expression ISO triptolide results in increased expression of H4C9 mRNA CTD PMID:32835833 NCBI chr17:47,176,246...47,180,690
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr 4:41,797,152...41,806,539 		JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 increases expression ISO triptolide results in increased expression of H3C14 mRNA CTD PMID:32835833 NCBI chr 2:186,526,162...186,526,587
Ensembl chr 2:186,521,116...186,550,846 		JBrowse link
G Hk2 hexokinase 2 increases expression
decreases expression 		ISO triptolide results in increased expression of HK2 mRNA
triptolide results in decreased expression of HK2 mRNA 		CTD PMID:34087332 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HMGCR mRNA CTD PMID:31557376 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO triptolide results in decreased expression of HMGCS1 mRNA CTD PMID:32835833 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
decreases expression
affects expression
multiple interactions 		EXP
ISO 		triptolide results in increased expression of HMOX1 mRNA
triptolide results in decreased expression of HMOX1 mRNA; triptolide results in decreased expression of HMOX1 protein
triptolide affects the expression of HMOX1 mRNA
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]
[triptolide co-treated with catalpol co-treated with Saponins] results in increased expression of HMOX1 protein; [triptolide co-treated with catalpol] results in increased expression of HMOX1 protein; [triptolide co-treated with Saponins] results in increased expression of HMOX1 protein
bergenin inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]; Estradiol inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]; mitoquinone inhibits the reaction [triptolide results in decreased expression of HMOX1 mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]] 		CTD PMID:23639586 PMID:25169008 PMID:30682494 PMID:30836114 PMID:38735593 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of HNMT mRNA CTD PMID:32835833 NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482 		JBrowse link
G Hp haptoglobin increases expression EXP triptolide results in increased expression of HP protein CTD PMID:32519852 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518 		JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase decreases expression ISO triptolide results in decreased expression of HPD mRNA CTD PMID:32835833 NCBI chr12:39,042,246...39,053,596
Ensembl chr12:39,042,238...39,053,612 		JBrowse link
G Hpx hemopexin increases expression EXP triptolide results in increased expression of HPX protein CTD PMID:32519852 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases expression EXP triptolide results in decreased expression of HRAS mRNA CTD PMID:23639586 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hrg histidine-rich glycoprotein increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of HRG protein
triptolide results in decreased expression of HRG mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr11:91,559,087...91,573,982
Ensembl chr11:91,559,091...91,573,982 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO [Colforsin co-treated with triptolide] results in decreased expression of HSD3B2 mRNA CTD PMID:31557376 NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569 		JBrowse link
G Hsf2bp heat shock transcription factor 2 binding protein increases expression ISO triptolide results in increased expression of HSF2BP mRNA CTD PMID:32835833 NCBI chr20:10,035,263...10,121,262
Ensembl chr20:10,035,263...10,121,826 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO triptolide results in increased expression of HSP90AA1 mRNA CTD PMID:32835833 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases response to substance ISO HSPA1A results in decreased susceptibility to triptolide CTD PMID:19546256 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression EXP triptolide results in increased expression of HSPA1B protein CTD PMID:32519852 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression EXP triptolide results in increased expression of HSPA2 protein CTD PMID:32519852 NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like affects expression ISO triptolide affects the expression of HSPA4L mRNA CTD PMID:32835833 NCBI chr 2:125,668,346...125,726,404
Ensembl chr 2:125,668,236...125,720,986 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
multiple interactions
increases expression 		ISO triptolide results in decreased expression of HSPA5 protein
STING1 protein affects the reaction [triptolide results in increased expression of HSPA5 protein]; TRAJ18 protein affects the reaction [triptolide results in increased expression of HSPA5 mRNA]; TRAJ18 protein affects the reaction [triptolide results in increased expression of HSPA5 protein]
triptolide results in increased expression of HSPA5 mRNA; triptolide results in increased expression of HSPA5 protein 		CTD PMID:26990902 PMID:27022166 PMID:36520315 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP triptolide results in decreased expression of HSPD1 protein CTD PMID:32519852 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Htra4 HtrA serine peptidase 4 decreases expression ISO triptolide results in decreased expression of HTRA4 mRNA CTD PMID:32835833 NCBI chr16:73,704,255...73,717,722
Ensembl chr16:73,704,184...73,717,722 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
increases expression 		ISO triptolide results in decreased expression of ICAM1 mRNA; triptolide results in decreased expression of ICAM1 protein
TRAJ18 protein affects the reaction [triptolide results in increased expression of ICAM1 protein]
triptolide results in increased expression of ICAM1 mRNA; triptolide results in increased expression of ICAM1 protein 		CTD PMID:17931847 PMID:32835833 PMID:32987112 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO triptolide results in decreased expression of IDI1 mRNA CTD PMID:32835833 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Idua alpha-L-iduronidase increases expression ISO triptolide results in increased expression of IDUA mRNA CTD PMID:32835833 NCBI chr14:1,175,994...1,203,913
Ensembl chr14:1,176,577...1,204,066 		JBrowse link
G Ier5 immediate early response 5 increases expression ISO triptolide results in increased expression of IER5 mRNA CTD PMID:32835833 NCBI chr13:69,820,450...69,822,542
Ensembl chr13:69,820,451...69,822,543 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP triptolide results in increased expression of IFIT2 protein CTD PMID:32519852 NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression EXP triptolide results in increased expression of IFIT3 protein CTD PMID:32519852 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521 		JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO triptolide results in increased expression of IFNB1 mRNA CTD PMID:36520315 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:108,066,650...108,067,487 		JBrowse link
G Ifng interferon gamma multiple interactions
increases secretion 		ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD80 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD86 protein]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]
triptolide results in increased secretion of IFNG protein
IL12B protein affects the reaction [triptolide results in increased secretion of IFNG protein] 		CTD PMID:15663903 PMID:36520315 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 increases expression EXP triptolide results in increased expression of IGDCC3 protein CTD PMID:32519852 NCBI chr 8:74,556,348...74,603,136
Ensembl chr 8:74,556,348...74,603,136 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO triptolide results in decreased expression of IGF1 mRNA CTD PMID:32835833 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression ISO triptolide results in decreased expression of IGF2BP3 mRNA CTD PMID:32835833 NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 decreases expression EXP
ISO 		triptolide results in decreased expression of IGFBP1 mRNA CTD PMID:23639586 PMID:32835833 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO triptolide results in decreased expression of IGFBP4 mRNA CTD PMID:32835833 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Igg-2a gamma-2a immunoglobulin heavy chain increases expression EXP triptolide results in increased expression of IGG-2A protein CTD PMID:32519852
G Igtp interferon gamma induced GTPase increases expression EXP triptolide results in increased expression of IGTP protein CTD PMID:32519852 NCBI chr10:42,875,047...42,882,866
Ensembl chr10:42,876,790...42,882,858 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions
decreases phosphorylation 		ISO
EXP 		TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of IKBKB protein]
pifithrin inhibits the reaction [triptolide results in decreased phosphorylation of IKBKB protein] 		CTD PMID:31618665 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il10 interleukin 10 increases expression ISO triptolide results in increased expression of IL10 mRNA CTD PMID:36520315 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15663903 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B multiple interactions
affects secretion 		ISO triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; triptolide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL12B protein]
IL12B protein affects the reaction [triptolide results in increased expression of GPT protein]; IL12B protein affects the reaction [triptolide results in increased secretion of IFNG protein]; IL12B protein affects the reaction [triptolide results in increased secretion of IL4 protein]; STING1 protein affects the reaction [triptolide affects the secretion of IL12B protein] 		CTD PMID:15663903 PMID:36520315 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il13 interleukin 13 increases expression ISO triptolide results in increased expression of IL13 mRNA CTD PMID:36520315 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
decreases expression 		ISO IL17A protein promotes the reaction [triptolide results in increased expression of CCL11 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL1 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of CXCL2 mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of FASL mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]
triptolide results in increased expression of IL17A mRNA; triptolide results in increased expression of IL17A protein
triptolide results in decreased expression of IL17A mRNA 		CTD PMID:24949944 PMID:36520315 PMID:38115356 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331 		JBrowse link
G Il18 interleukin 18 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of IL18 mRNA
[triptolide co-treated with Lipopolysaccharides] results in increased expression of IL18 mRNA; [triptolide co-treated with Lipopolysaccharides] results in increased secretion of IL18 protein 		CTD PMID:32835833 PMID:36328986 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; [triptolide co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein; [triptolide co-treated with TNF protein] results in increased expression of IL1B mRNA; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of IL1B mRNA]; IL17A protein promotes the reaction [triptolide results in increased expression of IL1B mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:24949944 PMID:30633930 PMID:31241159 PMID:36328986 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il4 interleukin 4 increases secretion
multiple interactions 		ISO triptolide results in increased secretion of IL4 protein
IL12B protein affects the reaction [triptolide results in increased secretion of IL4 protein]; STING1 protein affects the reaction [triptolide results in increased secretion of IL4 protein] 		CTD PMID:32987112 PMID:36520315 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
affects expression 		ISO Chlormethiazole inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Chlormethiazole inhibits the reaction [triptolide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 protein]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
triptolide results in increased expression of IL6 mRNA; triptolide results in increased expression of IL6 protein
triptolide affects the expression of IL6 mRNA
Chlormethiazole inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Chlormethiazole inhibits the reaction [triptolide results in increased expression of IL6 protein]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of IL6 protein] 		CTD PMID:30633930 PMID:31241159 PMID:34758665 PMID:36520315 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression ISO triptolide results in increased expression of IMP4 mRNA CTD PMID:32835833 NCBI chr 9:44,150,029...44,155,167
Ensembl chr 9:44,150,337...44,157,751 		JBrowse link
G Impa2 inositol monophosphatase 2 decreases expression ISO triptolide results in decreased expression of IMPA2 mRNA CTD PMID:32835833 NCBI chr18:63,104,113...63,135,232
Ensembl chr18:63,104,083...63,137,543 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO triptolide results in increased expression of IMPDH2 mRNA CTD PMID:32835833 NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873 		JBrowse link
G Inava innate immunity activator increases expression ISO triptolide results in increased expression of INAVA mRNA CTD PMID:32835833 NCBI chr13:50,218,149...50,238,430
Ensembl chr13:50,218,150...50,238,454 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 affects expression ISO triptolide affects the expression of INCA1 mRNA CTD PMID:32835833 NCBI chr10:55,900,610...55,912,975
Ensembl chr10:55,900,610...55,912,698 		JBrowse link
G Inhca inhibitor of carbonic anhydrase increases expression EXP triptolide results in increased expression of INHCA protein CTD PMID:32519852 NCBI chr 8:112,715,733...112,753,950
Ensembl chr 8:112,702,085...112,766,829 		JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO triptolide results in increased expression of INKA2 mRNA CTD PMID:32835833 NCBI chr 2:195,873,617...195,888,983
Ensembl chr 2:195,873,497...195,893,605 		JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of INMT mRNA CTD PMID:32835833 NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755 		JBrowse link
G Insc INSC, spindle orientation adaptor protein affects expression ISO triptolide affects the expression of INSC mRNA CTD PMID:32835833 NCBI chr 1:178,427,360...178,534,827
Ensembl chr 1:178,427,423...178,535,047 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO triptolide results in decreased expression of INSIG1 mRNA CTD PMID:32835833 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insr insulin receptor increases expression EXP triptolide results in increased expression of INSR protein CTD PMID:32519852 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803 		JBrowse link
G Ints2 integrator complex subunit 2 increases expression ISO triptolide results in increased expression of INTS2 mRNA CTD PMID:32835833 NCBI chr10:71,529,021...71,576,529
Ensembl chr10:71,401,151...71,575,206 		JBrowse link
G Ipo13 importin 13 increases expression ISO triptolide results in increased expression of IPO13 mRNA CTD PMID:32835833 NCBI chr 5:136,719,204...136,740,118
Ensembl chr 5:136,719,204...136,741,847 		JBrowse link
G Irf3 interferon regulatory factor 3 increases expression ISO triptolide results in increased expression of IRF3 protein CTD PMID:36520315 NCBI chr 1:104,616,608...104,621,402
Ensembl chr 1:104,616,469...104,621,401 		JBrowse link
G Irgm immunity-related GTPase M increases expression EXP triptolide results in increased expression of IRGM protein CTD PMID:32519852 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228 		JBrowse link
G Irs1 insulin receptor substrate 1 increases degradation
multiple interactions 		ISO triptolide results in increased degradation of IRS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein]; triptolide results in decreased expression of and results in decreased phosphorylation of IRS1 protein 		CTD PMID:32061799 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 decreases expression EXP triptolide results in decreased expression of ISCA1 protein CTD PMID:32519852 NCBI chr17:4,910,816...4,923,478
Ensembl chr17:4,910,795...4,923,476 		JBrowse link
G Iscu iron-sulfur cluster assembly enzyme decreases expression EXP triptolide results in decreased expression of ISCU protein CTD PMID:32519852 NCBI chr12:48,512,852...48,518,696
Ensembl chr12:48,512,852...48,518,696 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 increases expression EXP triptolide results in increased expression of ISYNA1 protein CTD PMID:32519852 NCBI chr16:18,873,119...18,876,116
Ensembl chr16:18,873,121...18,875,955 		JBrowse link
G Itga5 integrin subunit alpha 5 increases expression EXP
ISO 		triptolide results in increased expression of ITGA5 protein
triptolide results in increased expression of ITGA5 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:136,358,097...136,381,305 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO triptolide results in increased expression of ITGAM mRNA CTD PMID:36520315 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 increases expression EXP triptolide results in increased expression of ITIH3 protein CTD PMID:32519852 NCBI chr16:6,108,378...6,123,609
Ensembl chr16:6,108,382...6,123,374 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 increases expression EXP triptolide results in increased expression of ITIH4 protein CTD PMID:32519852 NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression EXP triptolide results in increased expression of ITPR3 protein CTD PMID:32519852 NCBI chr20:5,138,553...5,204,189
Ensembl chr20:5,118,834...5,204,184 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO triptolide results in decreased expression of and results in decreased phosphorylation of JAK2 protein CTD PMID:38115356 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762 		JBrowse link
G Jph1 junctophilin 1 decreases expression ISO triptolide results in decreased expression of JPH1 mRNA CTD PMID:32835833 NCBI chr 5:6,813,553...6,920,488
Ensembl chr 5:6,813,602...6,906,241 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression ISO triptolide results in increased expression of JPT1 mRNA CTD PMID:32835833 NCBI chr10:101,243,428...101,261,464
Ensembl chr10:101,243,424...101,261,469 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO triptolide results in increased expression of JUN mRNA CTD PMID:32835833 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kctd18 potassium channel tetramerization domain containing 18 increases expression ISO triptolide results in increased expression of KCTD18 mRNA CTD PMID:32835833 NCBI chr 9:66,996,440...67,061,069
Ensembl chr 9:66,996,447...67,061,069 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression ISO triptolide results in decreased expression of KEAP1 protein CTD PMID:30682494 PMID:36990132 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Khsrp KH-type splicing regulatory protein decreases expression EXP triptolide results in decreased expression of KHSRP protein CTD PMID:32519852 NCBI chr 9:1,949,557...1,959,400
Ensembl chr 9:1,949,557...1,959,497 		JBrowse link
G Kif20a kinesin family member 20A increases expression ISO triptolide results in increased expression of KIF20A mRNA CTD PMID:32835833 NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909 		JBrowse link
G Kif21a kinesin family member 21A increases expression EXP triptolide results in increased expression of KIF21A protein CTD PMID:32519852 NCBI chr 7:123,942,079...124,058,594
Ensembl chr 7:123,942,081...124,058,540 		JBrowse link
G Kifc3 kinesin family member C3 increases expression ISO triptolide results in increased expression of KIFC3 mRNA CTD PMID:32835833 NCBI chr19:9,831,159...9,926,405
Ensembl chr19:9,831,159...9,926,405 		JBrowse link
G Klc1 kinesin light chain 1 increases expression ISO triptolide results in increased expression of KLC1 mRNA CTD PMID:32835833 NCBI chr 6:136,644,592...136,690,399
Ensembl chr 6:136,644,307...136,689,760 		JBrowse link
G Klhl26 kelch-like family member 26 increases expression ISO triptolide results in increased expression of KLHL26 mRNA CTD PMID:32835833 NCBI chr16:18,986,095...19,011,297
Ensembl chr16:18,985,865...19,011,297 		JBrowse link
G Klkb1 kallikrein B1 decreases expression ISO triptolide results in decreased expression of KLKB1 mRNA CTD PMID:32835833 NCBI chr16:53,690,180...53,714,570
Ensembl chr16:53,691,220...53,716,339 		JBrowse link
G Kng1 kininogen 1 increases expression EXP triptolide results in increased expression of KNG1 protein CTD PMID:32519852 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148 		JBrowse link
G Kng2 kininogen 2 increases expression EXP triptolide results in increased expression of MAP1 protein CTD PMID:32519852 NCBI chr11:91,418,470...91,440,841
Ensembl chr11:91,414,207...91,441,259 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP triptolide results in increased expression of KRAS mRNA CTD PMID:23639586 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO triptolide results in decreased expression of KYAT1 mRNA CTD PMID:32835833 NCBI chr 3:33,857,407...33,891,153
Ensembl chr 3:33,857,743...33,890,642 		JBrowse link
G Kyat3 kynurenine aminotransferase 3 decreases expression ISO triptolide results in decreased expression of KYAT3 mRNA CTD PMID:32835833 NCBI chr 2:234,362,306...234,407,646
Ensembl chr 2:234,362,322...234,407,878 		JBrowse link
G L1cam L1 cell adhesion molecule increases expression EXP triptolide results in increased expression of L1CAM protein CTD PMID:32519852 NCBI chr  X:156,748,597...156,775,116
Ensembl chr  X:156,748,597...156,775,077 		JBrowse link
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 decreases expression EXP triptolide results in decreased expression of LAMTOR1 protein CTD PMID:32519852 NCBI chr 1:165,684,001...165,689,698
Ensembl chr 1:165,684,091...165,703,178 		JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO triptolide results in increased expression of LCAT mRNA CTD PMID:32835833 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081 		JBrowse link
G Ldb3 LIM domain binding 3 increases expression ISO triptolide results in increased expression of LDB3 mRNA CTD PMID:32835833 NCBI chr16:9,862,161...9,926,338
Ensembl chr16:9,862,161...9,926,985 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO triptolide results in decreased expression of LDHA mRNA CTD PMID:34087332 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Lepr leptin receptor decreases expression ISO triptolide results in decreased expression of LEPR mRNA CTD PMID:32835833 NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215 		JBrowse link
G Letmd1 LETM1 domain containing 1 increases expression EXP triptolide results in increased expression of LETMD1 protein CTD PMID:32519852 NCBI chr 7:133,461,920...133,476,592
Ensembl chr 7:133,462,825...133,476,591 		JBrowse link
G Lgi4 leucine-rich repeat LGI family, member 4 increases expression ISO triptolide results in increased expression of LGI4 mRNA CTD PMID:32835833 NCBI chr 1:95,422,461...95,433,296
Ensembl chr 1:95,414,058...95,433,289 		JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO triptolide results in decreased expression of LIPG mRNA CTD PMID:32835833 NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO triptolide results in increased expression of LITAF mRNA CTD PMID:32835833 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930 		JBrowse link
G Lmna lamin A/C increases expression ISO triptolide results in increased expression of LMNA mRNA CTD PMID:32835833 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Lonrf3 LON peptidase N-terminal domain and ring finger 3 increases expression ISO triptolide results in increased expression of LONRF3 mRNA CTD PMID:32835833 NCBI chr  X:120,430,975...120,469,648
Ensembl chr  X:120,430,996...120,464,572 		JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression ISO triptolide results in increased expression of LOXL4 mRNA CTD PMID:32835833 NCBI chr 1:251,345,445...251,365,640
Ensembl chr 1:251,347,238...251,365,577 		JBrowse link
G Lpin1 lipin 1 decreases expression ISO triptolide results in decreased expression of LPIN1 mRNA CTD PMID:32835833 NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991 		JBrowse link
G Lpxn leupaxin increases expression ISO triptolide results in increased expression of LPXN mRNA CTD PMID:32835833 NCBI chr 1:219,353,319...219,387,743
Ensembl chr 1:219,353,708...219,387,742 		JBrowse link
G Lrrc14 leucine rich repeat containing 14 increases expression ISO triptolide results in increased expression of LRRC14 mRNA CTD PMID:32835833 NCBI chr 7:110,311,384...110,317,757
Ensembl chr 7:110,311,369...110,317,760 		JBrowse link
G Lrrc51 leucine rich repeat containing 51 increases expression ISO triptolide results in increased expression of LRRC51 mRNA CTD PMID:32835833 NCBI chr 1:165,690,617...165,709,837
Ensembl chr 1:165,690,111...165,698,842 		JBrowse link
G Lrrn4cl LRRN4 C-terminal like increases expression ISO triptolide results in increased expression of LRRN4CL mRNA CTD PMID:32835833 NCBI chr 1:215,172,689...215,192,627
Ensembl chr 1:215,174,216...215,198,343 		JBrowse link
G Lrtm1 leucine-rich repeats and transmembrane domains 1 decreases expression ISO triptolide results in decreased expression of LRTM1 mRNA CTD PMID:32835833 NCBI chr16:4,216,947...4,224,447 JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 increases expression ISO triptolide results in increased expression of ORAOV1 mRNA CTD PMID:32835833 NCBI chr 1:209,502,900...209,510,237
Ensembl chr 1:209,498,312...209,517,347 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression EXP triptolide results in increased expression of LY6E protein CTD PMID:32519852 NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443 		JBrowse link
G Mab21l3 mab-21 like 3 increases expression ISO triptolide results in increased expression of MAB21L3 mRNA CTD PMID:32835833 NCBI chr 2:191,937,451...191,960,204
Ensembl chr 2:191,937,451...191,960,204 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression EXP triptolide results in increased expression of MAD2L1 mRNA CTD PMID:23639586 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222 		JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression ISO triptolide results in decreased expression of MAFB mRNA CTD PMID:32835833 NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975 		JBrowse link
G Maff MAF bZIP transcription factor F affects expression ISO triptolide affects the expression of MAFF mRNA CTD PMID:32835833 NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO triptolide results in increased expression of MAP1LC3B protein CTD PMID:31218727 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO triptolide results in increased expression of MAP1S mRNA CTD PMID:32835833 NCBI chr16:18,551,573...18,561,760
Ensembl chr16:18,551,573...18,562,141 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 decreases expression ISO triptolide results in decreased expression of MAP2K6 mRNA CTD PMID:32835833 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 increases expression ISO triptolide results in increased expression of MAP3K20 mRNA CTD PMID:32835833 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538 		JBrowse link
G Map7d1 MAP7 domain containing 1 increases expression ISO triptolide results in increased expression of MAP7D1 mRNA CTD PMID:32835833 NCBI chr 5:143,812,467...143,837,597
Ensembl chr 5:143,811,924...143,837,021 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21717513 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] CTD PMID:17507666 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21717513 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 increases expression ISO triptolide results in increased expression of MAPK8IP3 mRNA CTD PMID:32835833 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:14,422,936...14,462,812 		JBrowse link
G Mast3 microtubule associated serine/threonine kinase 3 increases expression EXP triptolide results in increased expression of MAST3 protein CTD PMID:32519852 NCBI chr16:18,670,742...18,699,252
Ensembl chr16:18,670,765...18,697,832 		JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 increases expression EXP triptolide results in increased expression of MBNL1 protein CTD PMID:32519852 NCBI chr 2:146,789,570...146,964,136
Ensembl chr 2:146,789,596...146,964,134 		JBrowse link
G Mcee methylmalonyl CoA epimerase increases expression EXP triptolide results in increased expression of MCEE protein CTD PMID:32519852 NCBI chr 1:127,376,311...127,399,551
Ensembl chr 1:127,376,298...127,400,367 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO triptolide results in increased expression of MCL1 protein CTD PMID:26990902 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression EXP triptolide results in increased expression of MCM6 mRNA CTD PMID:23639586 NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467 		JBrowse link
G Mcrip1 MAPK regulated co-repressor interacting protein 1 increases expression ISO triptolide results in increased expression of MCRIP1 mRNA CTD PMID:32835833 NCBI chr10:106,318,985...106,326,442
Ensembl chr10:106,318,985...106,321,197 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
decreases expression 		ISO triptolide results in increased expression of MDM2 mRNA
triptolide results in decreased expression of MDM2 protein 		CTD PMID:32835833 PMID:36990132 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Me1 malic enzyme 1 decreases expression ISO triptolide results in decreased expression of ME1 mRNA CTD PMID:32835833 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275 		JBrowse link
G Med23 mediator complex subunit 23 increases expression EXP triptolide results in increased expression of MED23 protein CTD PMID:32519852 NCBI chr 1:22,309,613...22,377,745
Ensembl chr 1:22,309,613...22,356,754 		JBrowse link
G Mep1a meprin A subunit alpha increases expression EXP triptolide results in increased expression of MEP1A protein CTD PMID:32519852 NCBI chr 9:24,971,901...25,001,414
Ensembl chr 9:24,971,886...25,001,414 		JBrowse link
G Mep1b meprin A subunit beta increases expression EXP triptolide results in increased expression of MEP1B protein CTD PMID:32519852 NCBI chr18:12,641,041...12,667,759
Ensembl chr18:12,641,041...12,667,755 		JBrowse link
G Mfn1 mitofusin 1 decreases expression EXP triptolide results in decreased expression of MFN1 protein CTD PMID:31557070 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190 		JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of MFN2 protein
mitoquinone inhibits the reaction [triptolide results in decreased expression of MFN2 protein] 		CTD PMID:30836114 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid decreases expression ISO triptolide results in decreased expression of MFSD2A mRNA CTD PMID:32835833 NCBI chr 5:140,510,933...140,525,828
Ensembl chr 5:140,510,953...140,525,916 		JBrowse link
G Mfsd4b1 major facilitator superfamily domain containing 4B1 decreases expression ISO triptolide results in decreased expression of MFSD4B1 mRNA CTD PMID:32835833 NCBI chr20:44,991,384...45,004,590
Ensembl chr20:44,991,384...45,006,161 		JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 increases expression ISO triptolide results in increased expression of MICAL2 mRNA CTD PMID:32835833 NCBI chr 1:175,780,441...175,965,157
Ensembl chr 1:175,825,596...175,905,155 		JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 increases expression ISO triptolide results in increased expression of MICAL3 mRNA CTD PMID:32835833 NCBI chr 4:155,824,941...156,025,003
Ensembl chr 4:155,824,946...156,005,238 		JBrowse link
G Mir137 microRNA 137 multiple interactions ISO [triptolide co-treated with FASL protein] results in decreased expression of MIR137; [triptolide co-treated with FASL protein] results in increased expression of MIR137; MIR137 promotes the reaction [[triptolide co-treated with FASL protein] results in decreased expression of XIAP protein] CTD PMID:37944651 NCBI chr 2:209,165,709...209,165,810
Ensembl chr 2:209,165,712...209,165,813 		JBrowse link
G Mir141 microRNA 141 multiple interactions ISO [triptolide co-treated with tariquidar] results in increased activity of MIR141 protein CTD PMID:26134275 NCBI chr 4:159,209,525...159,209,618 JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO triptolide results in decreased expression of MKI67 protein CTD PMID:24842335 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein; [triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein modified form]; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MLKL protein]
triptolide results in increased expression of MLKL mRNA 		CTD PMID:30633930 PMID:32835833 NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858 		JBrowse link
G Mmd2 monocyte to macrophage differentiation-associated 2 decreases expression ISO triptolide results in decreased expression of MMD2 mRNA CTD PMID:32835833 NCBI chr12:17,075,870...17,123,255
Ensembl chr12:17,076,260...17,123,904 		JBrowse link
G Mme membrane metallo-endopeptidase increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of MME protein
triptolide results in decreased expression of MME mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO triptolide results in increased expression of MMP12 mRNA CTD PMID:32835833 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO triptolide results in decreased expression of MMP2 mRNA; triptolide results in decreased expression of MMP2 protein CTD PMID:26420756 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of MMP9 protein
triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; triptolide inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein] 		CTD PMID:25200491 PMID:26420756 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mogat2 monoacylglycerol O-acyltransferase 2 increases expression ISO triptolide results in increased expression of MOGAT2 mRNA CTD PMID:32835833 NCBI chr 1:162,933,964...162,957,896
Ensembl chr 1:162,933,966...162,957,896 		JBrowse link
G Mov10 Mov10 RNA helicase decreases expression ISO triptolide results in decreased expression of MOV10 mRNA CTD PMID:32835833 NCBI chr 2:194,982,014...195,003,513
Ensembl chr 2:194,982,014...195,003,442 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression EXP triptolide results in decreased expression of MPC1 protein CTD PMID:32519852 NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of MPO protein; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of MPO protein]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of MPO mRNA] CTD PMID:30633930 PMID:36328986 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 increases expression ISO triptolide results in increased expression of MPP7 mRNA CTD PMID:32835833 NCBI chr17:60,135,096...60,401,814
Ensembl chr17:60,137,701...60,401,739 		JBrowse link
G Mreg melanoregulin increases expression ISO triptolide results in increased expression of MREG mRNA CTD PMID:32835833 NCBI chr 9:81,236,019...81,291,601
Ensembl chr 9:81,236,019...81,291,310 		JBrowse link
G Mrps5 mitochondrial ribosomal protein S5 increases expression EXP triptolide results in increased expression of MRPS5 protein CTD PMID:32519852 NCBI chr 3:135,274,333...135,290,577
Ensembl chr 3:135,274,493...135,291,640 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO triptolide results in decreased expression of MSMO1 mRNA CTD PMID:32835833 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression EXP triptolide results in increased expression of ND1 protein CTD PMID:32519852 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,729...3,685 		JBrowse link
G Mt1 metallothionein 1 decreases expression
increases expression 		EXP triptolide results in decreased expression of MT1 protein
triptolide results in increased expression of MT1M protein 		CTD PMID:32519852 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mtdh metadherin increases expression ISO triptolide results in increased expression of MTDH mRNA CTD PMID:32835833 NCBI chr 7:67,192,592...67,250,819
Ensembl chr 7:67,192,393...67,249,584 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO triptolide results in increased expression of and results in increased phosphorylation of MTOR protein CTD PMID:26990902 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP triptolide results in increased expression of MUG1 protein CTD PMID:32519852 NCBI chr 4:156,748,351...156,802,132 JBrowse link
G Mug2 murinoglobulin 2 decreases expression ISO triptolide results in decreased expression of MUG2 mRNA CTD PMID:32835833 NCBI chr 4:156,836,140...156,908,972 JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of MVD protein
triptolide results in decreased expression of MVD mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr19:67,404,911...67,414,974
Ensembl chr19:67,404,911...67,422,366 		JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression EXP triptolide results in increased expression of MX1 protein CTD PMID:32519852 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression ISO triptolide results in increased expression of MYBL1 mRNA CTD PMID:32835833 NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression ISO triptolide results in increased expression of MYBL2 mRNA CTD PMID:32835833 NCBI chr 3:172,124,765...172,153,221
Ensembl chr 3:172,116,550...172,153,221 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression 		EXP
ISO 		triptolide results in decreased expression of MYC mRNA
triptolide results in decreased expression of MYC protein
triptolide results in increased expression of MYC mRNA 		CTD PMID:12533674 PMID:23639586 PMID:32835833 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Mycbpap Mycbp associated protein increases expression ISO triptolide results in increased expression of MYCBPAP mRNA CTD PMID:32835833 NCBI chr10:79,947,200...79,967,857
Ensembl chr10:79,947,200...79,967,918 		JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor decreases expression ISO triptolide results in decreased expression of MYCL mRNA CTD PMID:32835833 NCBI chr 5:140,559,843...140,566,704
Ensembl chr 5:140,560,152...140,566,699 		JBrowse link
G Myh1 myosin heavy chain 1 decreases expression ISO triptolide results in decreased expression of MYH1 mRNA CTD PMID:32061799 NCBI chr10:52,384,810...52,408,698
Ensembl chr10:52,384,908...52,409,047 		JBrowse link
G Myh2 myosin heavy chain 2 decreases expression ISO triptolide results in decreased expression of MYH2 mRNA CTD PMID:32061799 NCBI chr10:52,355,739...52,382,235
Ensembl chr10:52,355,739...52,382,235 		JBrowse link
G Myh4 myosin heavy chain 4 decreases expression ISO triptolide results in decreased expression of MYH4 mRNA CTD PMID:32061799 NCBI chr10:52,422,148...52,445,296
Ensembl chr10:52,421,951...52,445,294 		JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO triptolide results in decreased expression of MYH7 mRNA CTD PMID:32061799 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Myh7b myosin heavy chain 7B increases expression ISO triptolide results in increased expression of MYH7B mRNA CTD PMID:32835833 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:164,558,340...164,582,094 		JBrowse link
G Myl9 myosin light chain 9 decreases expression EXP triptolide results in decreased expression of MYL9 protein CTD PMID:32519852 NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO triptolide inhibits the reaction [Luteolin inhibits the reaction [decabromobiphenyl ether results in increased expression of MYLK protein]] CTD PMID:33675858 NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659 		JBrowse link
G Myo19 myosin XIX increases expression ISO triptolide results in increased expression of MYO19 mRNA CTD PMID:32835833 NCBI chr10:70,250,500...70,279,867
Ensembl chr10:70,250,022...70,279,858 		JBrowse link
G Myo5c myosin VC increases expression EXP triptolide results in increased expression of MYO5C protein CTD PMID:32519852 NCBI chr 8:84,870,031...84,946,996
Ensembl chr 8:84,870,043...84,946,996 		JBrowse link
G Myom1 myomesin 1 increases expression ISO triptolide results in increased expression of MYOM1 mRNA CTD PMID:32835833 NCBI chr 9:118,362,547...118,485,954
Ensembl chr 9:118,362,621...118,485,952 		JBrowse link
G Myrfl myelin regulatory factor-like increases expression ISO triptolide results in increased expression of MYRFL mRNA CTD PMID:32835833 NCBI chr 7:54,289,430...54,406,097
Ensembl chr 7:54,289,332...54,405,868 		JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression ISO triptolide results in decreased expression of NAALADL2 mRNA CTD PMID:32835833 NCBI chr 2:108,568,000...109,920,650
Ensembl chr 2:108,573,985...109,920,756 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase decreases expression ISO triptolide results in decreased expression of NAMPT mRNA CTD PMID:29723566 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544 		JBrowse link
G Nat8f4 N-acetyltransferase 8 (GCN5-related) family member 4 increases expression ISO triptolide results in increased expression of NAT8F4 mRNA CTD PMID:32835833 NCBI chr 4:119,883,557...119,890,066
Ensembl chr 4:119,879,639...119,890,276 		JBrowse link
G Nat8f5 N-acetyltransferase 8 (GCN5-related) family member 5 affects expression ISO triptolide affects the expression of NAT8F5 mRNA CTD PMID:32835833 NCBI chr 4:119,817,788...119,842,503
Ensembl chr 4:119,816,735...119,863,953 		JBrowse link
G Nbeal2 neurobeachin-like 2 increases expression ISO triptolide results in increased expression of NBEAL2 mRNA CTD PMID:32835833 NCBI chr 8:119,481,608...119,511,997
Ensembl chr 8:119,481,608...119,514,384 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 increases expression ISO triptolide results in increased expression of NCBP1 mRNA CTD PMID:32835833 NCBI chr 5:65,211,632...65,244,532
Ensembl chr 5:65,211,358...65,244,665 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 increases expression EXP triptolide results in increased expression of NCOA6 protein CTD PMID:32519852 NCBI chr 3:164,351,062...164,422,079
Ensembl chr 3:164,351,062...164,421,991 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 increases expression ISO triptolide results in increased expression of NCOR2 mRNA CTD PMID:32835833 NCBI chr12:37,127,736...37,289,612
Ensembl chr12:37,127,686...37,289,612 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 increases expression ISO triptolide results in increased expression of NDOR1 mRNA CTD PMID:32835833 NCBI chr 3:28,460,787...28,469,018
Ensembl chr 3:28,460,797...28,469,018 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 increases expression EXP triptolide results in increased expression of NDUFA7 protein CTD PMID:32519852 NCBI chr 7:15,311,446...15,324,226
Ensembl chr 7:15,311,286...15,334,138 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions
decreases expression 		EXP
ISO 		7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]]
triptolide results in decreased expression of NDUFB8 mRNA; triptolide results in decreased expression of NDUFB8 protein 		CTD PMID:36436616 NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:253,357,841...253,362,936 		JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 increases expression EXP triptolide results in increased expression of NDUFB9 protein CTD PMID:32519852 NCBI chr 7:92,370,423...92,376,841
Ensembl chr 7:92,370,467...92,379,955 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 increases expression EXP triptolide results in increased expression of NDUFS4 protein CTD PMID:32519852 NCBI chr 2:47,684,420...47,794,914
Ensembl chr 2:47,684,406...47,794,931 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO triptolide results in decreased expression of NDUFS8 mRNA CTD PMID:29723566 NCBI chr 1:210,569,823...210,573,707
Ensembl chr 1:210,569,824...210,572,971 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression EXP triptolide results in increased expression of NDUFV3 protein CTD PMID:32519852 NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847 		JBrowse link
G Necap1 NECAP endocytosis associated 1 decreases expression EXP triptolide results in decreased expression of NECAP1 protein CTD PMID:32519852 NCBI chr 4:157,775,890...157,790,992
Ensembl chr 4:157,775,896...157,790,984 		JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO triptolide results in increased expression of NETO2 mRNA CTD PMID:32835833 NCBI chr19:37,517,518...37,588,961
Ensembl chr19:37,517,587...37,591,413 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases response to substance
affects localization
decreases expression
affects expression
decreases phosphorylation
increases expression 		EXP
ISO 		Acetylcysteine inhibits the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in increased ubiquitination of NFE2L2 protein]; Lithium Chloride affects the reaction [triptolide affects the expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased abundance of Glutathione]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of GCLC protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of NQO1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased abundance of Reactive Oxygen Species]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased expression of APAF1 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased expression of BAX protein]; triptolide affects the expression of and results in increased ubiquitination of NFE2L2 protein
NFE2L2 protein results in decreased susceptibility to triptolide
triptolide affects the localization of NFE2L2 protein
triptolide results in decreased expression of NFE2L2 protein
triptolide affects the expression of NFE2L2 mRNA; triptolide affects the expression of NFE2L2 protein
triptolide results in decreased phosphorylation of NFE2L2 protein
[catalpol co-treated with Saponins co-treated with triptolide] affects the localization of NFE2L2 protein; [catalpol co-treated with triptolide] affects the localization of NFE2L2 protein; [Saponins co-treated with triptolide] affects the localization of NFE2L2 protein; [triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein; [triptolide co-treated with Saponins] results in increased expression of NFE2L2 protein; catalpol inhibits the reaction [Saponins inhibits the reaction [triptolide results in decreased phosphorylation of NFE2L2 protein]]; catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [catalpol promotes the reaction [Saponins inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in increased expression of GPT protein]]]; NFE2L2 protein affects the reaction [triptolide results in decreased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [triptolide results in increased expression of GPT protein]; NFE2L2 protein inhibits the reaction [triptolide affects the expression of CDKN1A protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; NFE2L2 protein inhibits the reaction [triptolide results in increased expression of TP53 protein]; Saponins inhibits the reaction [triptolide results in decreased phosphorylation of NFE2L2 protein]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NFE2L2 protein]; Saponins promotes the reaction [catalpol inhibits the reaction [triptolide results in decreased expression of NFE2L2 mRNA]]; triptolide affects the reaction [NFE2L2 protein binds to TP53 protein]; triptolide results in decreased expression of and affects the localization of NFE2L2 protein
bergenin inhibits the reaction [triptolide results in decreased expression of NFE2L2 protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein]; mitoquinone inhibits the reaction [triptolide results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased activity of CAT1 protein]]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of BCL2 protein]]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of HMOX1 protein]]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of SOD1 protein]]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in increased cleavage of CASP9 protein]]; triptolide results in decreased expression of and affects the localization of NFE2L2 protein
triptolide results in increased expression of NFE2L2 mRNA; triptolide results in increased expression of NFE2L2 protein 		CTD PMID:22820427 PMID:25169008 PMID:30682494 PMID:30836114 PMID:30926361 More... NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases phosphorylation 		ISO
EXP 		TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of NFKBIA protein] CTD PMID:31618665 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO triptolide results in increased expression of NFKBIE mRNA CTD PMID:32835833 NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872 		JBrowse link
G Ngf nerve growth factor increases expression
increases secretion 		EXP triptolide results in increased expression of NGF mRNA; triptolide results in increased expression of NGF protein
triptolide results in increased secretion of NGF protein 		CTD PMID:17401680 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO triptolide results in increased expression of TNFRSF10B mRNA; triptolide results in increased expression of TNFRSF10B protein CTD PMID:26990902 PMID:32835833 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:81,012,089...81,030,305 		JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression EXP triptolide results in increased expression of FAM129A protein CTD PMID:32519852 NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 increases expression ISO triptolide results in increased expression of NIFK mRNA CTD PMID:32835833 NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561 		JBrowse link
G Nipal1 NIPA-like domain containing 1 decreases expression ISO triptolide results in decreased expression of NIPAL1 mRNA CTD PMID:32835833 NCBI chr14:35,891,645...35,915,658
Ensembl chr14:35,891,647...35,915,658 		JBrowse link
G Nle1 notchless homolog 1 increases expression ISO triptolide results in increased expression of NLE1 mRNA CTD PMID:32835833 NCBI chr10:68,331,609...68,342,562
Ensembl chr10:68,331,609...68,340,386 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 mRNA; [triptolide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [triptolide co-treated with TNF protein] results in increased expression of NLRP3 mRNA; [triptolide co-treated with TNF protein] results in increased expression of NLRP3 protein; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of NLRP3 protein]
triptolide results in increased expression of NLRP3 mRNA 		CTD PMID:36328986 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO triptolide results in decreased expression of NNMT mRNA CTD PMID:32835833 NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression EXP triptolide results in increased expression of NNT protein CTD PMID:32519852 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO triptolide results in increased expression of NOC2L mRNA CTD PMID:32835833 NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:172,101,223...172,114,162 		JBrowse link
G Nol6 nucleolar protein 6 increases expression ISO triptolide results in increased expression of NOL6 mRNA CTD PMID:32835833 NCBI chr 5:61,055,863...61,083,249
Ensembl chr 5:61,055,863...61,083,264 		JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 increases expression ISO triptolide results in increased expression of NOLC1 mRNA CTD PMID:32835833 NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:254,870,319...254,881,069 		JBrowse link
G Nop2 NOP2 nucleolar protein increases expression ISO triptolide results in increased expression of NOP2 mRNA CTD PMID:32835833 NCBI chr 4:159,618,894...159,630,697
Ensembl chr 4:159,618,966...159,630,697 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO triptolide results in increased expression of NOP56 mRNA CTD PMID:32835833 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959 		JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression ISO triptolide results in increased expression of NOP58 mRNA CTD PMID:32835833 NCBI chr 9:68,614,992...68,638,911
Ensembl chr 9:68,615,010...68,638,909 		JBrowse link
G Nop9 NOP9 nucleolar protein increases expression ISO triptolide results in increased expression of NOP9 mRNA CTD PMID:32835833 NCBI chr15:33,213,786...33,222,147
Ensembl chr15:33,213,789...33,222,147 		JBrowse link
G Notch1 notch receptor 1 multiple interactions
decreases expression
increases expression 		ISO NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of HES1 protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of CASP3 protein modified form]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of PTEN protein]; NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of TXNIP protein]
triptolide results in decreased expression of NOTCH1 mRNA; triptolide results in decreased expression of NOTCH1 protein; triptolide results in decreased expression of NOTCH1 protein modified form 		CTD PMID:30394310 PMID:31241159 PMID:32835833 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613 		JBrowse link
G Notch3 notch receptor 3 increases expression
multiple interactions 		ISO triptolide results in increased expression of NOTCH3 mRNA; triptolide results in increased expression of NOTCH3 protein
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] 		CTD PMID:31241159 NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,784,272...11,834,778 		JBrowse link
G Nox4 NADPH oxidase 4 decreases expression ISO triptolide results in decreased expression of NOX4 mRNA CTD PMID:32835833 NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin multiple interactions ISO
EXP 		triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS1 protein] CTD PMID:18509322 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521 		JBrowse link
G Nphs2 NPHS2 stomatin family member, podocin multiple interactions ISO
EXP 		triptolide inhibits the reaction [Puromycin Aminonucleoside results in decreased expression of NPHS2 protein] CTD PMID:18509322 NCBI chr13:70,993,622...71,011,585
Ensembl chr13:70,999,186...71,011,572 		JBrowse link
G Npm2 nucleophosmin/nucleoplasmin 2 increases expression ISO triptolide results in increased expression of NPM2 mRNA CTD PMID:32835833 NCBI chr15:52,131,973...52,145,710
Ensembl chr15:52,132,058...52,139,027 		JBrowse link
G Nprl3 NPR3-like, GATOR1 complex subunit increases expression ISO triptolide results in increased expression of NPRL3 mRNA CTD PMID:32835833 NCBI chr10:15,859,739...15,900,261
Ensembl chr10:15,859,789...15,902,332 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
increases expression
affects expression 		ISO
EXP 		triptolide results in decreased expression of NQO1 mRNA; triptolide results in decreased expression of NQO1 protein
NFE2L2 protein inhibits the reaction [triptolide results in decreased expression of NQO1 protein]
[triptolide co-treated with catalpol] results in increased expression of NQO1 protein; [triptolide co-treated with Saponins] results in increased expression of NQO1 protein; catalpol promotes the reaction [[triptolide co-treated with Saponins] results in increased expression of NQO1 protein]; Saponins promotes the reaction [[triptolide co-treated with catalpol] results in increased expression of NQO1 protein]
mitoquinone inhibits the reaction [triptolide results in decreased expression of NQO1 mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of NQO1 protein]
triptolide results in increased expression of NQO1 protein
triptolide affects the expression of NQO1 protein 		CTD PMID:25169008 PMID:30682494 PMID:30836114 PMID:32519852 PMID:36990132 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of NR0B2 mRNA
[triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR0B2 protein; [triptolide co-treated with TNF protein] results in decreased expression of NR0B2 protein; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in decreased expression of NR0B2 protein]; Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of NR0B2 mRNA]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR0B2 protein] 		CTD PMID:30633930 PMID:36328986 NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 decreases expression ISO triptolide results in decreased expression of NR1D1 mRNA CTD PMID:32835833 NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 decreases expression ISO triptolide results in decreased expression of NR1D2 mRNA CTD PMID:32835833 NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of NR1H4 mRNA; triptolide results in decreased expression of NR1H4 protein
[triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR1H4 mRNA; [triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR1H4 protein; [triptolide co-treated with TNF protein] results in decreased expression of NR1H4 protein; Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in decreased expression of NR1H4 protein]; TRAJ18 protein affects the reaction [triptolide results in decreased expression of NR1H4 protein] 		CTD PMID:30633930 PMID:32987112 PMID:36328986 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO triptolide inhibits the reaction [Rifampin results in increased activity of NR1I2 protein] CTD PMID:35678845 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression
decreases expression 		ISO
EXP 		triptolide results in increased expression of and results in increased phosphorylation of NR3C1 protein
triptolide results in increased expression of NR3C1 mRNA
triptolide results in decreased expression of NR3C1 mRNA 		CTD PMID:19330649 PMID:23639586 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nrf1 nuclear respiratory factor 1 decreases expression
multiple interactions 		ISO
EXP 		triptolide results in decreased expression of NRF1 mRNA
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of and affects the localization of NRF1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NRF1 mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NRF1 mRNA]]; triptolide results in decreased expression of and affects the localization of NRF1 protein 		CTD PMID:29723566 PMID:36436616 NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353 		JBrowse link
G Nrg4 neuregulin 4 decreases expression ISO triptolide results in decreased expression of NRG4 mRNA CTD PMID:32835833 NCBI chr 8:64,483,559...64,555,671
Ensembl chr 8:64,488,722...64,573,439 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO triptolide results in increased expression of NRIP1 mRNA CTD PMID:32835833 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL decreases expression ISO triptolide results in decreased expression of NSDHL mRNA CTD PMID:32835833 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Nsun3 NOP2/Sun RNA methyltransferase 3 increases expression ISO triptolide results in increased expression of NSUN3 mRNA CTD PMID:32835833 NCBI chr11:50,960,187...51,062,366
Ensembl chr11:50,960,192...51,045,220 		JBrowse link
G Nt5c 5', 3'-nucleotidase, cytosolic increases expression EXP triptolide results in increased expression of NT5C protein CTD PMID:32519852 NCBI chr10:101,238,552...101,240,666
Ensembl chr10:101,238,576...101,240,865 		JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 increases expression EXP triptolide results in increased expression of IFIT1 protein CTD PMID:32519852 NCBI chr 7:91,573,816...91,593,980
Ensembl chr 7:91,553,676...91,626,071 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 decreases expression EXP triptolide results in decreased expression of NTRK1 mRNA CTD PMID:23639586 NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:175,534,844...175,551,787 		JBrowse link
G Nubp2 NUBP iron-sulfur cluster assembly factor 2 increases expression ISO triptolide results in increased expression of NUBP2 mRNA CTD PMID:32835833 NCBI chr10:14,407,743...14,411,428
Ensembl chr10:14,407,745...14,411,600 		JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO triptolide results in decreased expression of NUDT7 mRNA CTD PMID:32835833 NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994 		JBrowse link
G Nup210l nucleoporin 210-like increases expression ISO triptolide results in increased expression of NUP210L mRNA CTD PMID:32835833 NCBI chr 2:177,843,647...177,962,975
Ensembl chr 2:177,845,633...177,962,969 		JBrowse link
G Nyx nyctalopin increases expression ISO triptolide results in increased expression of NYX mRNA CTD PMID:32835833 NCBI chr  X:11,953,680...11,974,716
Ensembl chr  X:11,953,018...11,974,810 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A increases expression EXP triptolide results in increased expression of OAS1A protein CTD PMID:32519852 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP triptolide results in increased expression of OASL protein CTD PMID:32519852 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 increases expression ISO triptolide results in increased expression of OAZ3 mRNA CTD PMID:32835833 NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:184,762,245...184,771,428 		JBrowse link
G Ociad2 OCIA domain containing 2 decreases expression ISO triptolide results in decreased expression of OCIAD2 mRNA CTD PMID:32835833 NCBI chr14:35,225,291...35,243,306
Ensembl chr14:35,225,255...35,243,311 		JBrowse link
G Ocln occludin multiple interactions
decreases expression 		ISO mitoquinone inhibits the reaction [triptolide results in decreased expression of OCLN mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of OCLN protein]
triptolide results in decreased expression of OCLN mRNA; triptolide results in decreased expression of OCLN protein 		CTD PMID:30836114 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411 		JBrowse link
G Odad4 outer dynein arm docking complex subunit 4 decreases expression ISO triptolide results in decreased expression of ODAD4 mRNA CTD PMID:32835833 NCBI chr10:85,980,440...86,008,943
Ensembl chr10:85,980,440...86,008,943 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression ISO triptolide results in increased expression of ODC1 mRNA CTD PMID:32835833 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Olfm3 olfactomedin 3 decreases expression ISO triptolide results in decreased expression of OLFM3 mRNA CTD PMID:32835833 NCBI chr 2:205,417,962...205,640,479
Ensembl chr 2:205,598,959...205,640,479 		JBrowse link
G Olfml1 olfactomedin-like 1 decreases expression ISO triptolide results in decreased expression of OLFML1 mRNA CTD PMID:32835833 NCBI chr 1:170,889,912...170,914,300
Ensembl chr 1:170,889,980...170,915,762 		JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression EXP triptolide results in increased expression of ORC1 mRNA CTD PMID:23639586 NCBI chr 5:128,552,975...128,581,943
Ensembl chr 5:128,552,991...128,577,071 		JBrowse link
G Orc3 origin recognition complex, subunit 3 increases expression EXP triptolide results in increased expression of ORC3 mRNA CTD PMID:23639586 NCBI chr 5:53,923,264...53,977,869
Ensembl chr 5:53,923,393...53,978,115 		JBrowse link
G Ovca2 OVCA2 serine hydrolase domain containing increases expression ISO triptolide results in increased expression of OVCA2 mRNA CTD PMID:32835833 NCBI chr10:60,524,385...60,527,547
Ensembl chr10:60,522,026...60,527,536 		JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP triptolide results in increased expression of P2RX7 protein CTD PMID:32519852 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO triptolide results in increased expression of P4HA1 mRNA CTD PMID:32835833 NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,845,141...27,895,404 		JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like increases expression ISO triptolide results in increased expression of PABPC1L mRNA CTD PMID:32835833 NCBI chr 3:173,111,856...173,145,389
Ensembl chr 3:173,112,904...173,146,038 		JBrowse link
G Pank1 pantothenate kinase 1 decreases expression ISO triptolide results in decreased expression of PANK1 mRNA CTD PMID:32835833 NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824 		JBrowse link
G Pard3b par-3 family cell polarity regulator beta decreases expression ISO triptolide results in decreased expression of PARD3B mRNA CTD PMID:32835833 NCBI chr 9:70,532,358...71,561,044
Ensembl chr 9:70,532,644...71,560,554 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
increases expression
multiple interactions 		ISO triptolide results in increased cleavage of PARP1 protein
triptolide results in increased expression of PARP1 protein
[triptolide co-treated with Lipopolysaccharides] results in increased expression of PARP1 protein modified form; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of PARP1 protein modified form]; mitoquinone inhibits the reaction [triptolide results in increased cleavage of PARP1 protein] 		CTD PMID:12533674 PMID:15972136 PMID:26990902 PMID:30633930 PMID:30836114 More... NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 increases expression EXP triptolide results in increased expression of PARP14 protein CTD PMID:32519852 NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 increases expression EXP triptolide results in increased expression of PARP9 protein CTD PMID:32519852 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608 		JBrowse link
G Pbx4 PBX homeobox 4 decreases expression ISO triptolide results in decreased expression of PBX4 mRNA CTD PMID:32835833 NCBI chr16:19,588,998...19,624,016
Ensembl chr16:19,588,999...19,623,921 		JBrowse link
G Pcif1 phosphorylated CTD interacting factor 1 increases expression ISO triptolide results in increased expression of PCIF1 mRNA CTD PMID:32835833 NCBI chr 3:174,033,471...174,046,403
Ensembl chr 3:174,034,675...174,049,395 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression
multiple interactions 		EXP
ISO 		triptolide results in decreased expression of PCK1 mRNA; triptolide results in decreased expression of PCK1 protein
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of PCK1 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of PCK1 mRNA] 		CTD PMID:23639586 PMID:30633930 PMID:32519852 PMID:32835833 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pcp4l1 Purkinje cell protein 4-like 1 affects expression ISO triptolide affects the expression of PCP4L1 mRNA CTD PMID:32835833 NCBI chr13:86,121,463...86,145,097
Ensembl chr13:86,121,464...86,144,899 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO triptolide results in decreased expression of PCSK9 mRNA CTD PMID:32835833 NCBI chr 5:126,440,102...126,462,507
Ensembl chr 5:126,440,102...126,462,507 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO triptolide results in decreased expression of PDK1 mRNA CTD PMID:32835833 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 decreases expression EXP triptolide results in decreased expression of PDK2 mRNA CTD PMID:31618665 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO triptolide results in increased expression of PDK4 mRNA CTD PMID:32835833 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP triptolide results in decreased expression of PDLIM1 protein CTD PMID:32519852 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 increases expression EXP triptolide results in increased expression of PDPK1 mRNA CTD PMID:23639586 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Pds5a PDS5 cohesin associated factor A decreases expression EXP triptolide results in decreased expression of PDS5A protein CTD PMID:32519852 NCBI chr14:42,905,734...43,004,740
Ensembl chr14:42,905,328...43,004,740 		JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression ISO triptolide results in decreased expression of PEMT mRNA CTD PMID:32835833 NCBI chr10:45,275,434...45,349,651
Ensembl chr10:45,275,412...45,420,037 		JBrowse link
G Pfkm phosphofructokinase, muscle increases expression EXP triptolide results in increased expression of PFKM protein CTD PMID:32519852 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:131,100,753...131,138,248 		JBrowse link
G Pfkp phosphofructokinase, platelet increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of PFKP protein
triptolide results in decreased expression of PFKP mRNA; triptolide results in decreased expression of PFKP protein; triptolide results in decreased expression of PFKP protein modified form 		CTD PMID:32519852 PMID:34087332 NCBI chr17:68,639,749...68,704,055
Ensembl chr17:68,639,481...68,705,752 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 decreases expression EXP triptolide results in decreased expression of PGAM2 mRNA CTD PMID:31618665 NCBI chr14:84,895,763...84,897,874
Ensembl chr14:84,895,744...84,897,894 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression
decreases expression 		ISO triptolide results in increased expression of PGK1 mRNA
triptolide results in decreased expression of PGK1 mRNA 		CTD PMID:34087332 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:75,336,687...75,352,959 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 increases expression ISO triptolide results in increased expression of PGS1 mRNA CTD PMID:32835833 NCBI chr10:103,713,306...103,748,924
Ensembl chr10:103,713,316...103,749,233 		JBrowse link
G Phb2 prohibitin 2 increases expression EXP triptolide results in increased expression of PHB2 protein CTD PMID:32519852 NCBI chr 4:159,203,948...159,208,561
Ensembl chr 4:159,203,926...159,209,231 		JBrowse link
G Phf5a PHD finger protein 5A increases expression EXP triptolide results in increased expression of PHF5A protein CTD PMID:32519852 NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO triptolide results in increased expression of PHLDA3 mRNA CTD PMID:32835833 NCBI chr13:49,745,003...49,748,088
Ensembl chr13:49,742,591...49,749,621 		JBrowse link
G Phrf1 PHD and ring finger domains 1 increases expression ISO triptolide results in increased expression of PHRF1 mRNA CTD PMID:32835833 NCBI chr 1:205,763,264...205,796,478
Ensembl chr 1:205,763,549...205,801,557 		JBrowse link
G Phyhd1 phytanoyl-CoA dioxygenase domain containing 1 decreases expression ISO triptolide results in decreased expression of PHYHD1 mRNA CTD PMID:32835833 NCBI chr 3:33,933,487...33,951,614
Ensembl chr 3:33,937,898...33,951,614 		JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein increases expression ISO triptolide results in increased expression of PHYHIP mRNA CTD PMID:32835833 NCBI chr15:51,943,670...51,954,921
Ensembl chr15:51,943,378...51,954,920 		JBrowse link
G Pigl phosphatidylinositol glycan anchor biosynthesis, class L increases expression ISO triptolide results in increased expression of PIGL mRNA CTD PMID:32835833 NCBI chr10:47,641,478...47,699,200
Ensembl chr10:47,641,098...47,699,453 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 increases expression ISO triptolide results in increased expression of PIK3R3 mRNA CTD PMID:32835833 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase increases expression ISO triptolide results in increased expression of PIM2 mRNA CTD PMID:32835833 NCBI chr  X:17,289,509...17,294,778
Ensembl chr  X:17,289,509...17,294,778 		JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting increases expression ISO triptolide results in increased expression of PKD1L3 mRNA CTD PMID:32835833 NCBI chr19:54,494,529...54,559,596
Ensembl chr19:54,495,243...54,559,546 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP
ISO 		triptolide results in decreased expression of PKLR mRNA CTD PMID:23639586 PMID:32835833 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pkm pyruvate kinase M1/2 decreases expression ISO triptolide results in decreased expression of PKM mRNA CTD PMID:34087332 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396 		JBrowse link
G Pla2g3 phospholipase A2, group III increases expression ISO triptolide results in increased expression of PLA2G3 mRNA CTD PMID:32835833 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542 		JBrowse link
G Pla2g4e phospholipase A2, group IVE increases expression ISO triptolide results in increased expression of PLA2G4B mRNA CTD PMID:32835833 NCBI chr 3:127,586,318...127,652,369
Ensembl chr 3:127,587,027...127,651,868 		JBrowse link
G Plcb3 phospholipase C beta 3 increases expression EXP triptolide results in increased expression of PLCB3 protein CTD PMID:32519852 NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583 		JBrowse link
G Plch2 phospholipase C, eta 2 increases expression ISO triptolide results in increased expression of PLCH2 mRNA CTD PMID:32835833 NCBI chr 5:170,826,543...170,885,012
Ensembl chr 5:170,826,543...170,885,152 		JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 decreases expression ISO triptolide results in decreased expression of PLCXD1 mRNA CTD PMID:32835833 NCBI chr12:52,238,450...52,241,884
Ensembl chr12:52,238,623...52,241,865 		JBrowse link
G Pld6 phospholipase D family, member 6 decreases expression ISO triptolide results in decreased expression of PLD6 mRNA CTD PMID:32835833 NCBI chr10:45,078,081...45,080,732
Ensembl chr10:45,077,080...45,087,160 		JBrowse link
G Plec plectin increases expression ISO triptolide results in increased expression of PLEC mRNA CTD PMID:32835833 NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089 		JBrowse link
G Plekha1 pleckstrin homology domain containing A1 decreases expression EXP triptolide results in decreased expression of PLEKHA1 protein CTD PMID:32519852 NCBI chr 1:194,858,239...194,909,418
Ensembl chr 1:194,851,547...194,909,413 		JBrowse link
G Plekha4 pleckstrin homology domain containing A4 increases expression ISO triptolide results in increased expression of PLEKHA4 mRNA CTD PMID:32835833 NCBI chr 1:105,142,296...105,165,297
Ensembl chr 1:105,142,348...105,165,297 		JBrowse link
G Plekhb1 pleckstrin homology domain containing B1 decreases expression ISO triptolide results in decreased expression of PLEKHB1 mRNA CTD PMID:32835833 NCBI chr 1:164,410,901...164,425,216
Ensembl chr 1:164,410,903...164,428,568 		JBrowse link
G Plekhf1 pleckstrin homology and FYVE domain containing 1 decreases expression ISO triptolide results in decreased expression of PLEKHF1 mRNA CTD PMID:32835833 NCBI chr 1:100,045,340...100,046,817
Ensembl chr 1:100,027,056...100,053,452 		JBrowse link
G Plekhh1 pleckstrin homology, MyTH4 and FERM domain containing H1 increases expression ISO triptolide results in increased expression of PLEKHH1 mRNA CTD PMID:32835833 NCBI chr 6:103,572,304...103,621,729
Ensembl chr 6:103,572,291...103,621,728 		JBrowse link
G Plg plasminogen increases expression EXP triptolide results in increased expression of PLG protein CTD PMID:32519852 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320 		JBrowse link
G Plk1 polo-like kinase 1 increases expression EXP triptolide results in increased expression of PLK1 mRNA CTD PMID:23639586 NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:186,147,658...186,157,637 		JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO triptolide results in increased expression of PLK2 mRNA CTD PMID:32835833 NCBI chr 2:43,702,536...43,708,305
Ensembl chr 2:43,701,865...43,708,296 		JBrowse link
G Plpp1 phospholipid phosphatase 1 increases expression EXP triptolide results in increased expression of PLPP1 protein CTD PMID:32519852 NCBI chr 2:46,172,202...46,233,632
Ensembl chr 2:46,172,197...46,234,676 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression EXP triptolide results in increased expression of PLPP3 protein CTD PMID:32519852 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Pml PML nuclear body scaffold increases expression EXP triptolide results in increased expression of PML protein CTD PMID:32519852 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing decreases expression EXP triptolide results in decreased expression of PNKD protein CTD PMID:32519852 NCBI chr 9:83,317,757...83,386,263
Ensembl chr 9:83,317,738...83,386,262 		JBrowse link
G Pnp purine nucleoside phosphorylase increases expression ISO triptolide results in increased expression of PNP2 mRNA CTD PMID:32835833 NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression ISO triptolide results in decreased expression of PNPLA3 mRNA CTD PMID:32835833 NCBI chr 7:117,173,485...117,194,065
Ensembl chr 7:117,173,516...117,194,594 		JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression EXP triptolide results in increased expression of PNPLA7 protein CTD PMID:32519852 NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 decreases expression EXP triptolide results in decreased expression of PNPLA8 protein CTD PMID:32519852 NCBI chr 6:67,056,783...67,118,714
Ensembl chr 6:67,056,697...67,120,512 		JBrowse link
G Polk DNA polymerase kappa increases expression ISO triptolide results in increased expression of POLK mRNA CTD PMID:32835833 NCBI chr 2:29,556,831...29,616,960
Ensembl chr 2:29,557,336...29,616,960 		JBrowse link
G Polr1e RNA polymerase I subunit E increases expression ISO triptolide results in increased expression of POLR1E mRNA CTD PMID:32835833 NCBI chr 5:64,075,123...64,090,900
Ensembl chr 5:64,075,122...64,091,039 		JBrowse link
G Polr2a RNA polymerase II subunit A increases expression ISO triptolide results in increased expression of POLR2A mRNA CTD PMID:32835833 NCBI chr10:54,951,162...54,977,179
Ensembl chr10:54,951,162...54,977,179 		JBrowse link
G Polr2l RNA polymerase II, I and III subunit L increases expression ISO triptolide results in increased expression of POLR2L mRNA CTD PMID:32835833 NCBI chr 1:205,999,607...206,001,615
Ensembl chr19:8,341,868...8,342,071 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
affects response to substance 		ISO POR protein results in increased hydroxylation of and results in decreased abundance of triptolide
POR protein affects the susceptibility to triptolide 		CTD PMID:21596114 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 increases expression ISO triptolide results in increased expression of POU4F1 mRNA CTD PMID:32835833 NCBI chr15:87,668,328...87,674,643
Ensembl chr15:87,668,328...87,674,643 		JBrowse link
G Ppan peter pan homolog increases expression ISO triptolide results in increased expression of PPAN mRNA CTD PMID:32835833 NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:27,700,152...27,704,128 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases expression 		ISO triptolide results in decreased expression of PPARA mRNA; triptolide results in decreased expression of PPARA protein
triptolide results in increased expression of PPARA mRNA 		CTD PMID:26219505 PMID:29723566 PMID:31241159 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression
increases expression 		ISO triptolide results in decreased expression of PPARD protein
triptolide results in increased expression of PPARD mRNA 		CTD PMID:26219505 PMID:32835833 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression 		ISO
EXP 		resveratrol inhibits the reaction [triptolide affects the localization of and results in increased acetylation of PPARGC1A protein]; triptolide affects the localization of and results in increased acetylation of PPARGC1A protein; triptolide results in decreased expression of and results in decreased activity of PPARGC1A protein
triptolide results in decreased expression of PPARGC1A mRNA
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of and affects the localization of PPARGC1A protein]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of PPARGC1A protein]]; triptolide results in increased acetylation of and affects the localization of PPARGC1A protein 		CTD PMID:29723566 PMID:32835833 PMID:36436616 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta decreases expression ISO triptolide results in decreased expression of PPARGC1B mRNA CTD PMID:32835833 NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466 		JBrowse link
G Ppid peptidylprolyl isomerase D increases expression EXP triptolide results in increased expression of PPID protein CTD PMID:32519852 NCBI chr 2:167,025,985...167,037,998
Ensembl chr 2:167,025,931...167,054,493 		JBrowse link
G Ppl periplakin increases expression EXP triptolide results in increased expression of PPL protein CTD PMID:32519852 NCBI chr10:10,957,388...11,003,035
Ensembl chr10:10,957,341...11,003,658 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP triptolide results in decreased expression of PPP1CB mRNA CTD PMID:23639586 NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924 		JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 increases expression ISO triptolide results in increased expression of PPP1R11 mRNA CTD PMID:32835833 NCBI chr20:1,606,583...1,610,090
Ensembl chr20:1,606,577...1,613,212 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C increases expression EXP triptolide results in increased expression of PPP1R3C mRNA CTD PMID:23639586 NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835 		JBrowse link
G Ppp1r3d protein phosphatase 1, regulatory subunit 3D increases expression EXP triptolide results in increased expression of PPP1R3D mRNA CTD PMID:23639586 NCBI chr 3:185,880,087...185,883,158
Ensembl chr 3:185,876,709...185,883,703 		JBrowse link
G Ppp1r3g protein phosphatase 1, regulatory subunit 3G decreases expression ISO triptolide results in decreased expression of PPP1R3G mRNA CTD PMID:32835833 NCBI chr17:29,080,407...29,083,739
Ensembl chr17:29,070,658...29,085,135 		JBrowse link
G Prdm9 PR/SET domain 9 increases expression ISO triptolide results in increased expression of PRDM9 mRNA CTD PMID:32835833 NCBI chr 1:65,178,666...65,198,851
Ensembl chr 1:65,178,666...65,198,737 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases expression EXP triptolide results in increased expression of PRKAA1 mRNA CTD PMID:23639586 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases expression EXP triptolide results in increased expression of PRKAA2 mRNA CTD PMID:23639586 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 increases expression EXP triptolide results in increased expression of PRKAB2 mRNA CTD PMID:23639586 NCBI chr 2:187,946,008...187,961,615
Ensembl chr 2:187,945,982...187,961,608 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP triptolide results in increased expression of PRKACA mRNA CTD PMID:23639586 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 decreases expression EXP triptolide results in decreased expression of PRKAG2 mRNA CTD PMID:23639586 NCBI chr 4:10,744,695...10,985,939
Ensembl chr 4:10,744,588...10,985,939 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases expression EXP triptolide results in increased expression of PRKAR2B mRNA CTD PMID:23639586 NCBI chr 6:54,291,143...54,381,639
Ensembl chr 6:54,291,151...54,381,411 		JBrowse link
G Prkca protein kinase C, alpha increases expression EXP triptolide results in increased expression of PRKCA protein CTD PMID:32519852 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II decreases expression EXP triptolide results in decreased expression of PRKCSH protein CTD PMID:32519852 NCBI chr 8:28,810,836...28,822,503
Ensembl chr 8:28,810,889...28,822,503 		JBrowse link
G Prkrip1 PRKR interacting protein 1 increases expression ISO triptolide results in increased expression of PRKRIP1 mRNA CTD PMID:32835833 NCBI chr12:26,107,422...26,128,404
Ensembl chr12:26,107,398...26,130,026 		JBrowse link
G Prmt7 protein arginine methyltransferase 7 increases expression ISO triptolide results in increased expression of PRMT7 mRNA CTD PMID:32835833 NCBI chr19:51,020,596...51,071,401
Ensembl chr19:51,020,512...51,072,424 		JBrowse link
G Prom1 prominin 1 multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of PROM1 protein] CTD PMID:24842335 NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002 		JBrowse link
G Proser2 proline and serine rich 2 affects expression ISO triptolide affects the expression of PROSER2 mRNA CTD PMID:32835833 NCBI chr17:77,061,371...77,096,788
Ensembl chr17:77,077,727...77,095,194 		JBrowse link
G Prpf3 pre-mRNA processing factor 3 increases expression ISO triptolide results in increased expression of PRPF3 mRNA CTD PMID:32835833 NCBI chr 2:186,067,980...186,092,427
Ensembl chr 2:186,067,162...186,092,427 		JBrowse link
G Prpf4b pre-mRNA processing factor 4B increases expression EXP triptolide results in increased expression of PRPF4B protein CTD PMID:32519852 NCBI chr17:30,190,721...30,230,153
Ensembl chr17:30,193,907...30,225,420 		JBrowse link
G Prss8 serine protease 8 decreases expression ISO triptolide results in decreased expression of PRSS8 mRNA CTD PMID:32835833 NCBI chr 1:191,966,701...191,971,271
Ensembl chr 1:191,966,701...191,971,193 		JBrowse link
G Psmb10 proteasome 20S subunit beta 10 increases expression EXP triptolide results in increased expression of PSMB10 protein CTD PMID:32519852 NCBI chr19:50,740,808...50,743,292
Ensembl chr19:50,740,811...50,743,210 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression EXP triptolide results in increased expression of PSMB9 protein CTD PMID:32519852 NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 increases expression ISO triptolide results in increased expression of PSRC1 mRNA CTD PMID:32835833 NCBI chr 2:198,710,427...198,715,001
Ensembl chr 2:198,705,839...198,714,997 		JBrowse link
G Pten phosphatase and tensin homolog increases expression
multiple interactions 		ISO triptolide results in increased expression of PTEN protein
NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of PTEN protein] 		CTD PMID:30394310 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO triptolide results in decreased expression of PTGDS mRNA CTD PMID:32835833 NCBI chr 3:28,680,044...28,682,978
Ensembl chr 3:28,680,044...28,682,978 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression 		ISO
EXP 		triptolide inhibits the reaction [Dipyridamole inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]
triptolide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; triptolide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
triptolide results in increased expression of PTGS2 protein 		CTD PMID:16765938 PMID:21717513 PMID:26420756 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression
increases expression 		ISO
EXP 		triptolide results in decreased expression of PTK2 mRNA; triptolide results in decreased expression of PTK2 protein
triptolide results in increased expression of PTK2 protein 		CTD PMID:26420756 PMID:26990902 PMID:32519852 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ptpdc1 protein tyrosine phosphatase domain containing 1 increases expression ISO triptolide results in increased expression of PTPDC1 mRNA CTD PMID:32835833 NCBI chr17:16,235,311...16,284,160
Ensembl chr17:16,235,263...16,284,158 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C increases expression EXP triptolide results in increased expression of PTPRC protein CTD PMID:32519852 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression EXP triptolide results in decreased expression of PTPRF mRNA CTD PMID:23639586 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426 		JBrowse link
G Ptrh1 peptidyl-tRNA hydrolase 1 homolog increases expression ISO triptolide results in increased expression of PTRH1 mRNA CTD PMID:32835833 NCBI chr 3:36,462,575...36,475,605
Ensembl chr 3:36,462,575...36,476,139 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression EXP triptolide results in increased expression of PTTG1 mRNA CTD PMID:23639586 NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309 		JBrowse link
G Pus7l pseudouridine synthase 7 like increases expression ISO triptolide results in increased expression of PUS7L mRNA CTD PMID:32835833 NCBI chr 7:127,538,785...127,561,936
Ensembl chr 7:127,538,558...127,561,798 		JBrowse link
G Pwp2 PWP2, small subunit processome component increases expression ISO triptolide results in increased expression of PWP2 mRNA CTD PMID:32835833 NCBI chr20:10,498,998...10,512,631
Ensembl chr20:10,499,013...10,513,309 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions
increases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of PYCARD mRNA; [triptolide co-treated with TNF protein] results in increased expression of PYCARD mRNA
triptolide results in increased expression of PYCARD mRNA 		CTD PMID:36328986 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419 		JBrowse link
G Pygl glycogen phosphorylase L decreases expression EXP triptolide results in decreased expression of PYGL mRNA CTD PMID:23639586 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated increases expression ISO triptolide results in increased expression of PYGM mRNA CTD PMID:32835833 NCBI chr 1:213,119,805...213,134,622
Ensembl chr 1:213,119,791...213,134,612 		JBrowse link
G Qsox2 quiescin sulfhydryl oxidase 2 increases expression ISO triptolide results in increased expression of QSOX2 mRNA CTD PMID:32835833 NCBI chr 3:29,433,091...29,462,739
Ensembl chr 3:29,433,091...29,463,036 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP triptolide results in increased expression of RAB5A protein CTD PMID:32519852 NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447 		JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression EXP triptolide results in decreased expression of RAC1 mRNA CTD PMID:27554044 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rad9b RAD9 checkpoint clamp component B increases expression ISO triptolide results in increased expression of RAD9B mRNA CTD PMID:32835833 NCBI chr12:39,878,221...39,909,254
Ensembl chr12:39,878,445...39,909,143 		JBrowse link
G Ralgdsl2 ral guanine nucleotide dissociation stimulator like 2 increases expression ISO triptolide results in increased expression of RGL2 mRNA CTD PMID:32835833 NCBI chr20:4,950,379...4,958,315
Ensembl chr20:4,950,381...4,958,135 		JBrowse link
G Rbks ribokinase decreases expression EXP triptolide results in decreased expression of RBKS protein CTD PMID:32519852 NCBI chr 6:30,467,724...30,544,284
Ensembl chr 6:30,467,726...30,544,294 		JBrowse link
G Rbp4 retinol binding protein 4 decreases expression EXP triptolide results in decreased expression of RBP4 protein CTD PMID:32519852 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:245,306,349...245,313,898 		JBrowse link
G Rcan1 regulator of calcineurin 1 increases expression ISO triptolide results in increased expression of RCAN1 mRNA CTD PMID:32835833 NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236 		JBrowse link
G Rccd1 RCC1 domain containing 1 increases expression ISO triptolide results in increased expression of RCCD1 mRNA CTD PMID:32835833 NCBI chr 1:143,681,124...143,690,817
Ensembl chr 1:143,681,035...143,690,362 		JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO triptolide results in decreased expression of RDH11 mRNA CTD PMID:32835833 NCBI chr 6:103,712,373...103,728,247
Ensembl chr 6:103,712,374...103,729,741 		JBrowse link
G Rdh16 retinol dehydrogenase 16 increases expression EXP triptolide results in increased expression of RDH2 protein CTD PMID:32519852 NCBI chr 7:65,499,763...65,510,304 JBrowse link
G Recql4 RecQ like helicase 4 increases expression ISO triptolide results in increased expression of RECQL4 mRNA CTD PMID:32835833 NCBI chr 7:110,304,092...110,311,426
Ensembl chr 7:110,304,094...110,311,258 		JBrowse link
G Reg3b regenerating family member 3 beta increases expression EXP triptolide results in increased expression of REG3B protein CTD PMID:32519852 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Reg3g regenerating family member 3 gamma increases expression EXP triptolide results in increased expression of REG3G protein CTD PMID:32519852 NCBI chr 4:112,482,183...112,484,738
Ensembl chr 4:112,482,183...112,484,738 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
increases phosphorylation 		EXP
ISO 		pifithrin inhibits the reaction [triptolide results in decreased expression of RELA protein]; triptolide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of RELA protein]
Chlormethiazole inhibits the reaction [triptolide results in increased phosphorylation of RELA protein]; pyrazole promotes the reaction [triptolide results in increased phosphorylation of RELA protein]; TRP53 protein affects the reaction [triptolide results in decreased expression of RELA protein] 		CTD PMID:21717513 PMID:31618665 PMID:34758665 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Retsat retinol saturase increases expression EXP triptolide results in increased expression of RETSAT protein CTD PMID:32519852 NCBI chr 4:106,211,459...106,220,222
Ensembl chr 4:106,211,436...106,229,552 		JBrowse link
G Rfx5 regulatory factor X5 increases expression ISO triptolide results in increased expression of RFX5 mRNA CTD PMID:32835833 NCBI chr 2:185,210,206...185,217,735
Ensembl chr 2:185,210,217...185,217,743 		JBrowse link
G RGD1309362 similar to interferon-inducible GTPase increases expression EXP triptolide results in increased expression of RGD1309362 protein CTD PMID:32519852 NCBI chr18:55,943,741...55,969,375
Ensembl chr18:55,943,264...55,994,435 		JBrowse link
G Rgn regucalcin decreases expression ISO triptolide results in decreased expression of RGN mRNA CTD PMID:32835833 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases expression EXP triptolide results in increased expression of RGS10 protein CTD PMID:32519852 NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression ISO triptolide results in decreased expression of RGS16 mRNA CTD PMID:32835833 NCBI chr13:68,421,480...68,443,312
Ensembl chr13:68,438,120...68,443,313 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP triptolide results in increased expression of RGS2 protein CTD PMID:32519852 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697 		JBrowse link
G Rhbg Rh family B glycoprotein increases expression EXP triptolide results in increased expression of RHBG protein CTD PMID:32519852 NCBI chr 2:176,002,886...176,015,201
Ensembl chr 2:176,002,887...176,015,609 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO
EXP 		triptolide results in decreased expression of RHOA protein
triptolide results in decreased expression of RHOA mRNA; triptolide results in decreased expression of RHOA protein 		CTD PMID:26420756 PMID:27554044 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rhob ras homolog family member B decreases expression EXP triptolide results in decreased expression of RHOB mRNA; triptolide results in decreased expression of RHOB protein CTD PMID:27554044 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rhof ras homolog family member F, filopodia associated increases expression ISO triptolide results in increased expression of RHOF mRNA CTD PMID:32835833 NCBI chr12:39,082,413...39,107,528
Ensembl chr12:39,091,979...39,107,528 		JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A increases expression ISO triptolide results in increased expression of RIC8A mRNA CTD PMID:32835833 NCBI chr 1:205,364,796...205,371,102
Ensembl chr 1:205,363,882...205,371,102 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [triptolide co-treated with Lipopolysaccharides] results in increased expression of RIPK1 protein; necrostatin-1 inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in increased expression of RIPK1 protein] CTD PMID:30633930 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression EXP triptolide results in increased expression of RIPK2 protein CTD PMID:32519852 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 increases expression ISO triptolide results in increased expression of RIPK3 mRNA CTD PMID:32835833 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025 		JBrowse link
G Rnf152 ring finger protein 152 decreases expression ISO triptolide results in decreased expression of RNF152 mRNA CTD PMID:32835833 NCBI chr13:21,838,634...21,918,000
Ensembl chr13:21,838,075...21,962,703 		JBrowse link
G Rnf20 ring finger protein 20 increases expression EXP triptolide results in increased expression of RNF20 protein CTD PMID:32519852 NCBI chr 5:68,771,507...68,797,240
Ensembl chr 5:68,771,535...68,797,240 		JBrowse link
G Rnf213 ring finger protein 213 increases expression EXP triptolide results in increased expression of RNF213 protein CTD PMID:32519852 NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148 		JBrowse link
G Rnf38 ring finger protein 38 increases expression ISO triptolide results in increased expression of RNF38 mRNA CTD PMID:32835833 NCBI chr 5:63,154,507...63,263,138
Ensembl chr 5:63,154,507...63,263,137 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO
EXP 		triptolide results in decreased expression of ROCK1 mRNA CTD PMID:26420756 PMID:27554044 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 decreases expression EXP triptolide results in decreased expression of ROCK2 mRNA CTD PMID:27554044 NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:45,407,965...45,502,771 		JBrowse link
G Ropn1l rhophilin associated tail protein 1-like decreases expression ISO triptolide results in decreased expression of ROPN1L mRNA CTD PMID:32835833 NCBI chr 2:84,153,529...84,164,216
Ensembl chr 2:84,153,529...84,164,415 		JBrowse link
G Rorc RAR-related orphan receptor C increases expression
decreases expression 		ISO triptolide results in increased expression of RORC mRNA
triptolide results in decreased expression of RORC mRNA; triptolide results in decreased expression of RORC protein 		CTD PMID:24949944 PMID:38115356 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Rpf2 ribosome production factor 2 homolog increases expression EXP triptolide results in increased expression of RPF2 protein CTD PMID:32519852 NCBI chr20:45,184,511...45,205,983
Ensembl chr20:45,184,512...45,206,001 		JBrowse link
G Rpgrip1 RPGR interacting protein 1 increases expression ISO triptolide results in increased expression of RPGRIP1 mRNA CTD PMID:32835833 NCBI chr15:27,282,997...27,341,021
Ensembl chr15:27,282,998...27,341,021 		JBrowse link
G Rpl24 ribosomal protein L24 increases expression EXP triptolide results in increased expression of RPL24 protein CTD PMID:32519852 NCBI chr11:58,122,997...58,128,405
Ensembl chr11:58,122,997...58,128,405 		JBrowse link
G Rpl28 ribosomal protein L28 increases expression EXP triptolide results in increased expression of RPL28 protein CTD PMID:32519852 NCBI chr 1:78,080,945...78,083,532
Ensembl chr 1:78,080,945...78,083,771 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO triptolide results in increased expression of RPS6KA3 mRNA CTD PMID:32835833 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor increases expression ISO triptolide results in increased expression of RRN3 mRNA CTD PMID:32835833 NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330 		JBrowse link
G Rrp12 ribosomal RNA processing 12 increases expression ISO triptolide results in increased expression of RRP12 mRNA CTD PMID:32835833 NCBI chr 1:250,621,707...250,655,318
Ensembl chr 1:250,621,707...250,655,318 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression EXP triptolide results in increased expression of RT1-A2 protein CTD PMID:32519852 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-CE7 RT1 class I, locus CE7 increases expression EXP triptolide results in increased expression of RT1-CE7 protein CTD PMID:32519852 NCBI chr20:3,438,878...3,441,825 JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression ISO triptolide results in increased expression of H2-DMA mRNA CTD PMID:32835833 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335 		JBrowse link
G Rundc3a RUN domain containing 3A increases expression ISO triptolide results in increased expression of RUNDC3A mRNA CTD PMID:32835833 NCBI chr10:87,852,746...87,861,903
Ensembl chr10:87,852,782...87,861,901 		JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression EXP triptolide results in increased expression of S100A10 protein CTD PMID:32519852 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP triptolide results in increased expression of S100A11 protein CTD PMID:32519852 NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression EXP triptolide results in increased expression of S100A4 protein CTD PMID:32519852 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G Sac3d1 SAC3 domain containing 1 increases expression ISO triptolide results in increased expression of SAC3D1 mRNA CTD PMID:32835833 NCBI chr 1:212,843,463...212,845,842
Ensembl chr 1:212,843,463...212,845,883 		JBrowse link
G Samd4a sterile alpha motif domain containing 4A increases expression ISO triptolide results in increased expression of SAMD4 mRNA CTD PMID:32835833 NCBI chr15:22,616,200...22,831,872
Ensembl chr15:22,614,287...22,831,872 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 increases expression EXP triptolide results in increased expression of SAMHD1 protein CTD PMID:32519852 NCBI chr 3:166,179,742...166,214,448
Ensembl chr 3:166,181,588...166,214,410 		JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component increases expression EXP triptolide results in increased expression of SAMM50 protein CTD PMID:32519852 NCBI chr 7:117,197,460...117,221,668
Ensembl chr 7:117,197,381...117,224,581 		JBrowse link
G Sap30bp SAP30 binding protein increases expression ISO triptolide results in increased expression of SAP30BP mRNA CTD PMID:32835833 NCBI chr10:101,664,714...101,697,430
Ensembl chr10:101,664,697...101,697,429 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 increases expression ISO triptolide results in increased expression of SARM1 mRNA CTD PMID:32835833 NCBI chr10:63,867,503...63,890,872
Ensembl chr10:63,867,503...63,890,872 		JBrowse link
G Sbno2 strawberry notch homolog 2 increases expression ISO triptolide results in increased expression of SBNO2 mRNA CTD PMID:32835833 NCBI chr 7:10,256,221...10,300,175
Ensembl chr 7:10,253,248...10,300,176 		JBrowse link
G Sc5d sterol-C5-desaturase decreases expression ISO triptolide results in decreased expression of SC5D mRNA CTD PMID:32835833 NCBI chr 8:51,526,669...51,538,277
Ensembl chr 8:51,529,346...51,538,277 		JBrowse link
G Scamp2 secretory carrier membrane protein 2 decreases expression EXP triptolide results in decreased expression of SCAMP2 protein CTD PMID:32519852 NCBI chr 8:66,861,504...66,888,151
Ensembl chr 8:66,861,537...66,888,150 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO triptolide results in decreased expression of SCD1 mRNA CTD PMID:32835833 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 increases expression ISO triptolide results in increased expression of SCN4A mRNA CTD PMID:32835833 NCBI chr10:91,745,459...91,796,452
Ensembl chr10:91,746,715...91,796,324 		JBrowse link
G Sdc4 syndecan 4 decreases expression EXP triptolide results in decreased expression of SDC4 protein CTD PMID:32519852 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:173,574,239...173,593,670 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B decreases expression
multiple interactions 		EXP
ISO 		triptolide results in decreased expression of SDHB mRNA; triptolide results in decreased expression of SDHB protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]] 		CTD PMID:36436616 NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667 		JBrowse link
G Sds serine dehydratase decreases expression ISO triptolide results in decreased expression of SDS mRNA CTD PMID:32835833 NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773 		JBrowse link
G Sema3f semaphorin 3F increases expression ISO triptolide results in increased expression of SEMA3F mRNA CTD PMID:32835833 NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206 		JBrowse link
G Serpina1 serpin family A member 1 increases expression EXP triptolide results in increased expression of SERPINA1 protein CTD PMID:32519852 NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703 		JBrowse link
G Serpina12 serpin family A member 12 decreases expression ISO triptolide results in decreased expression of SERPINA12 mRNA CTD PMID:32835833 NCBI chr 6:128,717,334...128,732,049
Ensembl chr 6:128,717,334...128,732,049 		JBrowse link
G Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C increases expression EXP triptolide results in increased expression of SERPINA3K protein CTD PMID:32519852 NCBI chr 6:129,007,578...129,014,988
Ensembl chr 6:128,829,577...129,014,971 		JBrowse link
G Serpina3n serpin family A member 3N increases expression EXP triptolide results in increased expression of SERPINA3N protein CTD PMID:32519852 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415 		JBrowse link
G Serpina6 serpin family A member 6 decreases expression ISO triptolide results in decreased expression of SERPINA6 mRNA CTD PMID:32835833 NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:128,544,831...128,555,139 		JBrowse link
G Serpinc1 serpin family C member 1 increases expression EXP triptolide results in increased expression of SERPINC1 protein CTD PMID:32519852 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643 		JBrowse link
G Sf3a2 splicing factor 3A subunit 2 increases expression EXP triptolide results in increased expression of SF3A2 protein CTD PMID:32519852 NCBI chr 7:9,560,182...9,566,205
Ensembl chr 7:9,560,182...9,566,205 		JBrowse link
G Sfn stratifin increases expression ISO triptolide results in increased expression of SFN mRNA; triptolide results in increased expression of SFN protein CTD PMID:26990902 PMID:32835833 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995 		JBrowse link
G Sh2d4a SH2 domain containing 4A decreases expression ISO triptolide results in decreased expression of SH2D4A mRNA CTD PMID:32835833 NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression EXP triptolide results in increased expression of SHC1 protein CTD PMID:32519852 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Simc1 SUMO-interacting motifs containing 1 increases expression ISO triptolide results in increased expression of SIMC1 mRNA CTD PMID:32835833 NCBI chr17:10,066,855...10,112,010
Ensembl chr17:10,066,855...10,120,237 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions 		EXP
ISO 		triptolide results in decreased expression of SIRT1 protein
[triptolide co-treated with resveratrol] results in increased expression of SIRT1 protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SIRT1 protein] 		CTD PMID:29723566 PMID:36436616 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
decreases expression 		ISO [triptolide co-treated with Lipopolysaccharides] results in decreased expression of SLC10A1 mRNA; [triptolide co-treated with Lipopolysaccharides] results in decreased expression of SLC10A1 protein; Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of SLC10A1 mRNA]; obeticholic acid inhibits the reaction [[triptolide co-treated with Lipopolysaccharides] results in decreased expression of SLC10A1 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of SLC10A1 mRNA] CTD PMID:30633930 PMID:32835833 PMID:36328986 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 increases expression EXP triptolide results in increased expression of SLC12A7 protein CTD PMID:32519852 NCBI chr 1:31,301,243...31,382,825
Ensembl chr 1:31,301,243...31,382,957 		JBrowse link
G Slc13a3 solute carrier family 13 member 3 affects expression
increases expression 		EXP
ISO 		triptolide affects the expression of SLC13A3 protein
triptolide results in increased expression of SLC13A3 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 3:174,561,174...174,623,893
Ensembl chr 3:174,561,168...174,623,895 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) increases expression EXP triptolide results in increased expression of SLC14A1 protein CTD PMID:32519852 NCBI chr18:73,840,568...73,883,925
Ensembl chr18:73,840,569...73,870,489 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression ISO triptolide results in increased expression of SLC16A1 mRNA CTD PMID:32835833 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 decreases expression ISO triptolide results in decreased expression of SLC16A7 mRNA CTD PMID:32835833 NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386 		JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression
affects expression 		EXP
ISO 		triptolide results in increased expression of SLC17A1 protein
triptolide affects the expression of SLC17A1 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,649,919...41,681,174 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 decreases expression ISO triptolide results in decreased expression of SLC17A8 mRNA CTD PMID:32835833 NCBI chr 7:25,881,557...25,936,837
Ensembl chr 7:25,881,557...25,935,410 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression EXP triptolide results in increased expression of SLC1A1 protein CTD PMID:32519852 NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:235,963,437...236,045,469 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO triptolide results in increased expression of SLC1A4 mRNA CTD PMID:32835833 NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO triptolide results in increased expression of SLC1A5 mRNA CTD PMID:32835833 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 decreases expression EXP triptolide results in decreased expression of SLC22A13 protein CTD PMID:32519852 NCBI chr 8:127,800,097...127,811,750
Ensembl chr 8:127,800,097...127,811,724 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 increases expression EXP triptolide results in increased expression of SLC22A18 protein CTD PMID:32519852 NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases expression
decreases expression 		EXP
ISO 		triptolide results in increased expression of SLC22A7 protein
triptolide results in decreased expression of SLC22A7 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc23a1 solute carrier family 23 member 1 increases expression EXP triptolide results in increased expression of SLC23A1 protein CTD PMID:32519852 NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,490,374...27,504,702 		JBrowse link
G Slc23a3 solute carrier family 23, member 3 increases expression ISO triptolide results in increased expression of SLC23A3 mRNA CTD PMID:32835833 NCBI chr 9:84,071,286...84,081,951
Ensembl chr 9:84,071,471...84,080,037 		JBrowse link
G Slc25a1 solute carrier family 25 member 1 decreases expression ISO triptolide results in decreased expression of SLC25A1 mRNA CTD PMID:32835833 NCBI chr11:96,560,054...96,563,071
Ensembl chr11:96,560,041...96,565,052 		JBrowse link
G Slc25a24 solute carrier family 25 member 24 increases expression EXP triptolide results in increased expression of SLC25A24 protein CTD PMID:32519852 NCBI chr 2:199,449,425...199,487,287
Ensembl chr 2:199,449,345...199,487,290 		JBrowse link
G Slc26a8 solute carrier family 26 member 8 increases expression ISO triptolide results in increased expression of SLC26A8 mRNA CTD PMID:32835833 NCBI chr20:6,687,207...6,751,184
Ensembl chr20:6,699,445...6,751,184 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 decreases expression EXP triptolide results in decreased expression of SLC29A1 protein CTD PMID:32519852 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression
multiple interactions
increases expression 		EXP
ISO 		triptolide results in decreased expression of SLC2A1 protein
pifithrin inhibits the reaction [triptolide results in decreased expression of SLC2A1 protein]
TRP53 protein affects the reaction [triptolide results in decreased expression of SLC2A1 protein]
triptolide results in decreased expression of SLC2A1 mRNA; triptolide results in decreased expression of SLC2A1 protein
triptolide results in increased expression of SLC2A1 mRNA 		CTD PMID:31618665 PMID:34087332 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of SLC2A2 mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of SLC2A2 mRNA] 		CTD PMID:30633930 PMID:32835833 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 affects expression
decreases expression 		ISO triptolide affects the expression of SLC2A3 mRNA
triptolide results in decreased expression of SLC2A3 mRNA; triptolide results in decreased expression of SLC2A3 protein 		CTD PMID:34087332 NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions
decreases expression 		ISO
EXP 		TRP53 protein affects the reaction [triptolide results in decreased expression of SLC2A4 protein]
pifithrin inhibits the reaction [triptolide results in decreased expression of SLC2A4 protein]
triptolide results in decreased expression of SLC2A4 mRNA; triptolide results in decreased expression of SLC2A4 protein 		CTD PMID:31618665 PMID:32835833 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc34a3 solute carrier family 34 member 3 decreases expression EXP triptolide results in decreased expression of SLC34A3 protein CTD PMID:32519852 NCBI chr 3:28,442,455...28,447,997
Ensembl chr 3:28,442,457...28,447,997 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression ISO triptolide results in decreased expression of SLC38A4 mRNA CTD PMID:32835833 NCBI chr 7:130,022,039...130,082,169
Ensembl chr 7:130,023,980...130,082,097 		JBrowse link
G Slc39a5 solute carrier family 39 member 5 decreases expression ISO triptolide results in decreased expression of SLC39A5 mRNA CTD PMID:32835833 NCBI chr 7:1,409,360...1,415,407
Ensembl chr 7:1,409,360...1,414,784 		JBrowse link
G Slc49a3 solute carrier family 49 member 3 decreases expression EXP triptolide results in decreased expression of MFSD7 protein CTD PMID:32519852 NCBI chr14:1,448,274...1,459,126
Ensembl chr14:1,450,674...1,459,126 		JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) increases expression EXP triptolide results in increased expression of SLC4A1 protein CTD PMID:32519852 NCBI chr10:87,807,010...87,823,274
Ensembl chr10:87,807,013...87,823,258 		JBrowse link
G Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 increases expression EXP triptolide results in increased expression of SLC7A12 protein CTD PMID:32519852 NCBI chr 2:88,800,954...88,868,117
Ensembl chr 2:88,800,979...88,868,103 		JBrowse link
G Slc7a2 solute carrier family 7 member 2 decreases expression ISO triptolide results in decreased expression of SLC7A2 mRNA CTD PMID:32835833 NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256 		JBrowse link
G Slc7a3 solute carrier family 7 member 3 increases expression ISO triptolide results in increased expression of SLC7A3 mRNA CTD PMID:32835833 NCBI chr  X:70,250,089...70,256,610
Ensembl chr  X:70,250,099...70,256,059 		JBrowse link
G Slc7a4 solute carrier family 7, member 4 decreases expression ISO triptolide results in decreased expression of SLC7A4 mRNA CTD PMID:32835833 NCBI chr11:96,939,456...96,943,127
Ensembl chr11:96,939,444...96,943,802 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 increases expression EXP triptolide results in increased expression of SLCO1A1 protein CTD PMID:32519852 NCBI chr 4:176,606,924...176,682,027
Ensembl chr 4:176,607,687...176,681,992 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO triptolide results in decreased expression of SLCO1A4 mRNA CTD PMID:32835833 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression
multiple interactions 		ISO triptolide results in decreased expression of SLCO1B2 mRNA
Lipopolysaccharides promotes the reaction [triptolide results in decreased expression of SLCO1B2 mRNA]; TRAJ18 protein affects the reaction [triptolide results in decreased expression of SLCO1B2 mRNA]; triptolide promotes the reaction [Lipopolysaccharides results in decreased expression of SLCO1B2 mRNA] 		CTD PMID:30633930 PMID:32987112 NCBI chr 4:176,282,577...176,355,557
Ensembl chr 4:176,282,584...176,351,083 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 increases expression EXP triptolide results in increased expression of SLCO2A1 protein CTD PMID:32519852 NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:112,467,160...112,551,921 		JBrowse link
G Slfn5 schlafen family member 5 increases expression EXP triptolide results in increased expression of SLFN5 protein CTD PMID:32519852 NCBI chr10:68,378,440...68,392,515
Ensembl chr10:68,378,449...68,392,544 		JBrowse link
G Slk STE20-like kinase increases expression EXP triptolide results in increased expression of SLK protein CTD PMID:32519852 NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829 		JBrowse link
G Smox spermine oxidase increases expression ISO triptolide results in increased expression of SMOX mRNA CTD PMID:32835833 NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170
Ensembl chr  X:139,184,798...139,220,170 		JBrowse link
G Smyd1 SET and MYND domain containing 1 increases expression ISO triptolide results in increased expression of SMYD1 mRNA CTD PMID:32835833 NCBI chr 4:104,757,281...104,811,307
Ensembl chr 4:104,760,475...104,870,081 		JBrowse link
G Sntg2 syntrophin, gamma 2 decreases expression ISO triptolide results in decreased expression of SNTG2 mRNA CTD PMID:32835833 NCBI chr 6:52,529,481...52,730,972
Ensembl chr 6:52,529,481...52,730,972 		JBrowse link
G Snx11 sorting nexin 11 increases expression ISO triptolide results in increased expression of SNX11 mRNA CTD PMID:32835833 NCBI chr10:82,238,475...82,249,264
Ensembl chr10:82,238,479...82,249,166 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP triptolide results in increased expression of SOCS1 mRNA CTD PMID:23639586 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression 		ISO bergenin inhibits the reaction [triptolide results in decreased expression of SOD1 protein]; Estradiol inhibits the reaction [triptolide results in decreased expression of SOD1 protein]; NFE2L2 protein affects the reaction [bergenin inhibits the reaction [triptolide results in decreased expression of SOD1 protein]] CTD PMID:38735593 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO triptolide results in increased expression of SOD2 protein CTD PMID:31218727 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO triptolide results in decreased expression of SOS1 protein CTD PMID:26420756 NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350 		JBrowse link
G Sox12 SRY-box transcription factor 12 decreases expression ISO triptolide results in decreased expression of SOX12 mRNA CTD PMID:32835833 NCBI chr 3:161,319,800...161,320,819
Ensembl chr 3:161,298,764...161,326,428 		JBrowse link
G Sox2 SRY-box transcription factor 2 multiple interactions ISO triptolide inhibits the reaction [cobaltous chloride results in increased expression of SOX2 protein] CTD PMID:24842335 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350 		JBrowse link
G Sp1 Sp1 transcription factor increases expression
decreases expression 		ISO triptolide results in increased expression of SP1 mRNA
triptolide results in decreased expression of SP1 protein 		CTD PMID:32835833 PMID:34087332 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513 		JBrowse link
G Spata2L spermatogenesis associated 2-like decreases expression ISO triptolide results in decreased expression of SPATA2L mRNA CTD PMID:32835833 NCBI chr19:68,177,599...68,182,122
Ensembl chr19:68,176,615...68,182,069 		JBrowse link
G Spatc1l spermatogenesis and centriole associated 1-like increases expression ISO triptolide results in increased expression of SPATC1L mRNA CTD PMID:32835833 NCBI chr20:12,073,542...12,082,866
Ensembl chr20:12,073,543...12,118,253 		JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex affects expression ISO triptolide affects the expression of SPC24 mRNA CTD PMID:32835833 NCBI chr 8:28,576,409...28,581,481
Ensembl chr 8:28,576,409...28,581,299 		JBrowse link
G Spcs1 signal peptidase complex subunit 1 increases expression EXP triptolide results in increased expression of SPCS1 protein CTD PMID:32519852 NCBI chr16:6,196,653...6,198,221
Ensembl chr16:6,196,654...6,198,468 		JBrowse link
G Spcs2 signal peptidase complex subunit 2 increases expression EXP triptolide results in increased expression of SPCS2 protein CTD PMID:32519852 NCBI chr 1:163,575,842...163,595,269
Ensembl chr 1:163,575,842...163,595,271 		JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 increases expression ISO triptolide results in increased expression of SPINK5 mRNA CTD PMID:32835833 NCBI chr18:36,515,347...36,584,038
Ensembl chr18:36,515,347...36,583,799 		JBrowse link
G Sptb spectrin, beta, erythrocytic increases expression EXP triptolide results in increased expression of SPTB protein CTD PMID:32519852 NCBI chr 6:101,043,512...101,170,389
Ensembl chr 6:101,045,216...101,170,278 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO triptolide results in decreased expression of SQLE mRNA CTD PMID:32835833 NCBI chr 7:92,758,175...92,773,049
Ensembl chr 7:92,757,409...92,773,050 		JBrowse link
G Sqor sulfide quinone oxidoreductase increases expression EXP triptolide results in increased expression of SQOR protein CTD PMID:32519852 NCBI chr 3:130,294,783...130,341,655
Ensembl chr 3:130,292,814...130,340,799 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression ISO triptolide results in decreased expression of SRD5A1 mRNA CTD PMID:32835833 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903 		JBrowse link
G Srp19 signal recognition particle 19 increases expression EXP triptolide results in increased expression of SRP19 protein CTD PMID:32519852 NCBI chr18:26,205,888...26,212,171
Ensembl chr18:26,205,796...26,226,635 		JBrowse link
G Srsf12 serine and arginine rich splicing factor 12 increases expression ISO triptolide results in increased expression of SRSF12 mRNA CTD PMID:32835833 NCBI chr 5:52,402,033...52,427,839
Ensembl chr 5:52,402,618...52,427,846 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO triptolide results in increased expression of SRXN1 mRNA CTD PMID:32835833 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP triptolide results in decreased expression of STAR mRNA; triptolide results in decreased expression of STAR protein CTD PMID:22592319 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 decreases expression ISO triptolide results in decreased expression of STARD4 mRNA CTD PMID:32835833 NCBI chr18:25,088,831...25,104,172
Ensembl chr18:25,091,255...25,104,172 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression EXP triptolide results in increased expression of STAT1 protein CTD PMID:32519852 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
multiple interactions 		ISO triptolide results in increased expression of STAT3 mRNA
triptolide results in decreased expression of and results in decreased phosphorylation of STAT3 protein 		CTD PMID:24949944 PMID:38115356 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 increases expression
multiple interactions 		ISO triptolide results in increased expression of STING1 mRNA
STING1 protein affects the reaction [triptolide affects the expression of CD40 protein]; STING1 protein affects the reaction [triptolide affects the secretion of IL12B protein]; STING1 protein affects the reaction [triptolide results in decreased expression of ADGRE1 mRNA]; STING1 protein affects the reaction [triptolide results in decreased expression of CD68 mRNA]; STING1 protein affects the reaction [triptolide results in increased expression of ATF4 protein]; STING1 protein affects the reaction [triptolide results in increased expression of ATF6 mRNA]; STING1 protein affects the reaction [triptolide results in increased expression of ATF6 protein]; STING1 protein affects the reaction [triptolide results in increased expression of CD1D1 protein]; STING1 protein affects the reaction [triptolide results in increased expression of CD69 protein]; STING1 protein affects the reaction [triptolide results in increased expression of DDIT3 mRNA]; STING1 protein affects the reaction [triptolide results in increased expression of DDIT3 protein]; STING1 protein affects the reaction [triptolide results in increased expression of GPT protein]; STING1 protein affects the reaction [triptolide results in increased expression of HSPA5 protein]; STING1 protein affects the reaction [triptolide results in increased secretion of IL4 protein]; triptolide results in increased expression of and affects the localization of STING1 protein 		CTD PMID:36520315 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947 		JBrowse link
G Stmn1 stathmin 1 decreases expression EXP triptolide results in decreased expression of STMN1 protein CTD PMID:32519852 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842 		JBrowse link
G Sts steroid sulfatase increases expression EXP triptolide results in increased expression of STS protein CTD PMID:32519852 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 increases expression ISO triptolide results in increased expression of STYXL1 mRNA CTD PMID:32835833 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:26,544,067...26,576,366 		JBrowse link
G Sucnr1 succinate receptor 1 decreases expression ISO triptolide results in decreased expression of SUCNR1 mRNA CTD PMID:32835833 NCBI chr 2:146,368,858...146,380,360
Ensembl chr 2:146,368,858...146,380,360 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 increases expression EXP triptolide results in increased expression of SUMO1 protein CTD PMID:32519852 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit increases expression ISO triptolide results in increased expression of SUPT5 mRNA CTD PMID:32835833 NCBI chr 1:92,714,276...92,745,489
Ensembl chr 1:92,714,281...92,744,445 		JBrowse link
G Susd2 sushi domain containing 2 decreases expression EXP triptolide results in decreased expression of SUSD2 protein CTD PMID:32519852 NCBI chr20:13,016,960...13,024,264
Ensembl chr20:13,016,907...13,024,264 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase decreases expression ISO triptolide results in decreased expression of SUV39H1 protein CTD PMID:19879315 NCBI chr  X:17,093,059...17,105,942
Ensembl chr  X:17,092,986...17,105,942 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 decreases expression ISO triptolide results in decreased expression of SUV39H1 protein CTD PMID:19879315 NCBI chr  X:146,828,818...146,831,485 JBrowse link
G Syap1 synapse associated protein 1 decreases expression EXP triptolide results in decreased expression of SYAP1 protein CTD PMID:32519852 NCBI chr  X:35,423,947...35,458,472
Ensembl chr  X:35,423,969...35,458,864 		JBrowse link
G Syde2 synapse defective Rho GTPase homolog 2 decreases expression ISO triptolide results in decreased expression of SYDE2 mRNA CTD PMID:32835833 NCBI chr 2:237,557,395...237,591,290
Ensembl chr 2:237,558,274...237,591,290 		JBrowse link
G Syne4 spectrin repeat containing nuclear envelope family member 4 decreases expression ISO triptolide results in decreased expression of SYNE4 mRNA CTD PMID:32835833 NCBI chr 1:94,696,866...94,701,230
Ensembl chr 1:94,696,609...94,701,230 		JBrowse link
G Synpo synaptopodin increases expression ISO triptolide results in increased expression of SYNPO mRNA CTD PMID:32835833 NCBI chr18:56,326,369...56,347,359
Ensembl chr18:56,319,571...56,353,306 		JBrowse link
G Syt12 synaptotagmin 12 increases expression ISO triptolide results in increased expression of SYT12 mRNA CTD PMID:32835833 NCBI chr 1:211,158,745...211,189,780
Ensembl chr 1:211,159,800...211,189,037 		JBrowse link
G Syt3 synaptotagmin 3 decreases expression ISO triptolide results in decreased expression of SYT3 mRNA CTD PMID:32835833 NCBI chr 1:104,017,341...104,032,046
Ensembl chr 1:104,017,379...104,032,045 		JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex increases expression ISO triptolide results in increased expression of SZT2 mRNA CTD PMID:32835833 NCBI chr 5:137,182,648...137,229,349
Ensembl chr 5:137,182,648...137,229,419 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions ISO triptolide inhibits the reaction [TAC1 protein results in increased expression of CXCL8 protein] CTD PMID:20348278 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C increases expression ISO triptolide results in increased expression of TAF1C mRNA CTD PMID:32835833 NCBI chr19:64,561,079...64,567,599
Ensembl chr19:64,560,562...64,567,599 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP triptolide results in increased expression of TAP1 protein CTD PMID:32519852 NCBI chr20:4,658,171...4,668,543
Ensembl chr20:4,658,172...4,668,810 		JBrowse link
G Tapbp TAP binding protein increases expression EXP triptolide results in increased expression of TAPBP protein CTD PMID:32519852 NCBI chr20:4,958,821...4,967,958
Ensembl chr20:4,959,926...4,971,834 		JBrowse link
G Tardbp TAR DNA binding protein multiple interactions ISO triptolide inhibits the reaction [TARDBP protein binds to TARDBP protein] CTD PMID:23891805 NCBI chr 5:164,330,452...164,348,435
Ensembl chr 5:164,334,924...164,345,204 		JBrowse link
G Tas1r2 taste 1 receptor member 2 increases expression ISO triptolide results in increased expression of TAS1R2 mRNA CTD PMID:32835833 NCBI chr 5:157,192,799...157,208,937
Ensembl chr 5:157,192,799...157,208,937 		JBrowse link
G Tat tyrosine aminotransferase decreases expression
increases expression 		EXP
ISO 		triptolide results in decreased expression of TAT mRNA
triptolide results in increased expression of TAT mRNA 		CTD PMID:23639586 PMID:32835833 NCBI chr19:54,856,604...54,867,168
Ensembl chr19:54,856,563...54,867,482 		JBrowse link
G Tatdn2 TatD DNase domain containing 2 increases expression ISO triptolide results in increased expression of TATDN2 mRNA CTD PMID:32835833 NCBI chr 4:148,400,454...148,416,501
Ensembl chr 4:148,400,492...148,416,501 		JBrowse link
G Tbk1 TANK-binding kinase 1 increases expression ISO triptolide results in increased expression of TBK1 mRNA; triptolide results in increased expression of TBK1 protein CTD PMID:36520315 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357 		JBrowse link
G Tcea3 transcription elongation factor A3 decreases expression ISO triptolide results in decreased expression of TCEA3 mRNA CTD PMID:32835833 NCBI chr 5:153,760,401...153,792,934
Ensembl chr 5:153,760,407...153,792,930 		JBrowse link
G Tcf24 transcription factor 24 decreases expression ISO triptolide results in decreased expression of TCF24 mRNA CTD PMID:32835833 NCBI chr 5:14,057,482...14,064,615
Ensembl chr 5:14,058,039...14,063,345 		JBrowse link
G Tcta T-cell leukemia translocation altered increases expression ISO triptolide results in increased expression of TCTA mRNA CTD PMID:32835833 NCBI chr 8:117,867,153...117,871,132
Ensembl chr 8:117,867,153...117,871,331 		JBrowse link
G Tekt2 tektin 2 increases expression ISO triptolide results in increased expression of TEKT2 mRNA CTD PMID:32835833 NCBI chr 5:143,904,185...143,907,724
Ensembl chr 5:143,904,187...143,907,724 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B increases expression ISO triptolide results in increased expression of PAPD5 mRNA CTD PMID:32835833 NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399 		JBrowse link
G Testin testin gene increases expression EXP triptolide results in increased expression of TESTIN mRNA CTD PMID:27554044 NCBI chr17:3,829,012...3,864,995
Ensembl chr17:3,852,404...3,864,993 		JBrowse link
G Tex14 testis expressed 14, intercellular bridge forming factor increases expression ISO triptolide results in increased expression of TEX14 mRNA CTD PMID:32835833 NCBI chr10:72,729,017...72,859,697
Ensembl chr10:72,728,985...72,853,064 		JBrowse link
G Tf transferrin increases expression EXP triptolide results in increased expression of TF protein CTD PMID:32519852 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400 		JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression
multiple interactions 		ISO
EXP 		triptolide results in decreased expression of TFAM mRNA
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of TFAM mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of TFAM protein]
triptolide results in decreased expression of TFAM mRNA; triptolide results in decreased expression of TFAM protein 		CTD PMID:29723566 PMID:36436616 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877 		JBrowse link
G Tfb1m transcription factor B1, mitochondrial decreases expression ISO triptolide results in decreased expression of TFB1M mRNA CTD PMID:29723566 NCBI chr 1:46,520,510...46,567,004
Ensembl chr 1:46,524,435...46,566,948 		JBrowse link
G Tfb2m transcription factor B2, mitochondrial increases expression ISO triptolide results in increased expression of TFB2M mRNA CTD PMID:29723566 NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594 		JBrowse link
G Tfdp2 transcription factor Dp-2 increases expression EXP triptolide results in increased expression of TFDP2 mRNA CTD PMID:23639586 NCBI chr 8:105,640,018...105,781,026
Ensembl chr 8:105,640,033...105,781,001 		JBrowse link
G Tgfbr3l transforming growth factor beta receptor 3 like decreases expression ISO triptolide results in decreased expression of TGFBR3L mRNA CTD PMID:32835833 NCBI chr12:7,398,512...7,402,054
Ensembl chr12:7,398,717...7,402,054 		JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO triptolide results in decreased expression of THRSP mRNA CTD PMID:32835833 NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827 		JBrowse link
G Tiam2 TIAM Rac1 associated GEF 2 decreases expression ISO triptolide results in decreased expression of TIAM2 mRNA CTD PMID:32835833 NCBI chr 1:46,323,450...46,524,769
Ensembl chr 1:46,323,456...46,524,769 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression EXP triptolide results in increased expression of TIGAR mRNA CTD PMID:31618665 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:161,613,306...161,632,229 		JBrowse link
G Tipin timeless interacting protein increases expression ISO triptolide results in increased expression of TIPIN mRNA CTD PMID:32835833 NCBI chr 8:73,676,020...73,696,620
Ensembl chr 8:73,676,091...73,696,620 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression 		ISO mitoquinone inhibits the reaction [triptolide results in decreased expression of TJP1 mRNA]; mitoquinone inhibits the reaction [triptolide results in decreased expression of TJP1 protein]
triptolide results in decreased expression of TJP1 mRNA; triptolide results in decreased expression of TJP1 protein
triptolide inhibits the reaction [Luteolin inhibits the reaction [decabromobiphenyl ether results in decreased expression of TJP1 protein]] 		CTD PMID:30836114 PMID:33675858 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tk1 thymidine kinase 1 decreases expression ISO triptolide results in decreased expression of TK1 mRNA CTD PMID:32835833 NCBI chr10:103,533,449...103,544,818
Ensembl chr10:103,533,449...103,556,228 		JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression ISO triptolide results in decreased expression of TKFC mRNA CTD PMID:32835833 NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:216,661,477...216,677,928 		JBrowse link
G Tlcd2 TLC domain containing 2 decreases expression ISO triptolide results in decreased expression of TLCD2 mRNA CTD PMID:32835833 NCBI chr10:60,809,391...60,812,617
Ensembl chr10:60,809,391...60,811,599 		JBrowse link
G Tmed1 transmembrane p24 trafficking protein 1 increases expression EXP triptolide results in increased expression of TMED1 protein CTD PMID:32519852 NCBI chr 8:28,336,072...28,342,853
Ensembl chr 8:28,336,074...28,338,841 		JBrowse link
G Tmed8 transmembrane p24 trafficking protein family member 8 increases expression ISO triptolide results in increased expression of TMED8 mRNA CTD PMID:32835833 NCBI chr 6:112,537,921...112,572,199
Ensembl chr 6:112,542,932...112,572,383 		JBrowse link
G Tmem116 transmembrane protein 116 increases expression ISO triptolide results in increased expression of TMEM116 mRNA CTD PMID:32835833 NCBI chr12:40,681,346...40,750,106
Ensembl chr12:40,702,258...40,750,140 		JBrowse link
G Tmem17 transmembrane protein 17 increases expression ISO triptolide results in increased expression of TMEM17 mRNA CTD PMID:32835833 NCBI chr14:100,684,655...100,725,471
Ensembl chr14:100,685,093...100,725,470 		JBrowse link
G Tmem199 transmembrane protein 199 increases expression ISO triptolide results in increased expression of TMEM199 mRNA CTD PMID:32835833 NCBI chr10:63,900,543...63,905,115
Ensembl chr10:63,900,545...63,905,139 		JBrowse link
G Tmem222 transmembrane protein 222 increases expression ISO triptolide results in increased expression of TMEM222 mRNA CTD PMID:32835833 NCBI chr 5:150,749,746...150,763,031
Ensembl chr 5:150,749,748...150,767,278 		JBrowse link
G Tmem30a transmembrane protein 30A increases expression EXP triptolide results in increased expression of TMEM30A protein CTD PMID:32519852 NCBI chr 8:89,608,975...89,637,421
Ensembl chr 8:89,608,975...89,633,291 		JBrowse link
G Tmem43 transmembrane protein 43 increases expression ISO triptolide results in increased expression of TMEM43 mRNA CTD PMID:32835833 NCBI chr 4:125,534,844...125,549,986
Ensembl chr 4:125,534,813...125,549,988 		JBrowse link
G Tmem97 transmembrane protein 97 decreases expression ISO triptolide results in decreased expression of TMEM97 mRNA CTD PMID:32835833 NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818 		JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression ISO triptolide results in increased expression of TMPRSS2 mRNA CTD PMID:32835833 NCBI chr11:50,403,707...50,443,224
Ensembl chr11:50,398,349...50,443,114 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression 		ISO Chlormethiazole inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Chlormethiazole inhibits the reaction [triptolide results in increased expression of TNF protein]; pyrazole promotes the reaction [triptolide results in increased expression of TNF mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of TNF protein]; triptolide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
triptolide results in increased expression of TNF mRNA; triptolide results in increased expression of TNF protein
[triptolide co-treated with TNF protein] results in decreased expression of NR0B2 protein; [triptolide co-treated with TNF protein] results in decreased expression of NR1H4 protein; [triptolide co-treated with TNF protein] results in increased cleavage of CASP1 protein; [triptolide co-treated with TNF protein] results in increased cleavage of GSDMD protein; [triptolide co-treated with TNF protein] results in increased expression of IL1B mRNA; [triptolide co-treated with TNF protein] results in increased expression of NLRP3 mRNA; [triptolide co-treated with TNF protein] results in increased expression of NLRP3 protein; [triptolide co-treated with TNF protein] results in increased expression of PYCARD mRNA; Chlormethiazole inhibits the reaction [triptolide results in increased expression of TNF mRNA]; Chlormethiazole inhibits the reaction [triptolide results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of TNF mRNA]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in decreased expression of NR0B2 protein]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased cleavage of CASP1 protein]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased cleavage of GSDMD protein]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of IL1B mRNA]; GW 4064 inhibits the reaction [[triptolide co-treated with TNF protein] results in increased expression of NLRP3 protein]; pyrazole promotes the reaction [triptolide results in increased expression of TNF mRNA]; pyrazole promotes the reaction [triptolide results in increased expression of TNF protein]; triptolide promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] 		CTD PMID:17678712 PMID:24949944 PMID:30633930 PMID:31241159 PMID:32835833 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip8l3 TNF alpha induced protein 8 like 3 decreases expression ISO triptolide results in decreased expression of TNFAIP8L3 mRNA CTD PMID:32835833 NCBI chr 8:63,309,683...63,351,687
Ensembl chr 8:63,310,107...63,318,501 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b increases expression ISO triptolide results in increased expression of TNFRSF10A protein CTD PMID:26990902 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A increases expression ISO triptolide results in increased expression of TNFRSF12A mRNA CTD PMID:32835833 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO triptolide results in increased expression of TNFSF10 protein CTD PMID:26990902 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions
increases secretion
increases expression 		ISO 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased expression of TNNI3 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased secretion of TNNI3 protein] CTD PMID:30009776 PMID:36436616 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253 		JBrowse link
G Tnpo1 transportin 1 increases expression ISO triptolide results in increased expression of TNPO1 mRNA CTD PMID:32835833 NCBI chr 2:31,941,731...32,034,366
Ensembl chr 2:31,941,731...32,034,326 		JBrowse link
G Tor1b torsin family 1, member B increases expression ISO triptolide results in increased expression of TOR1B mRNA CTD PMID:32835833 NCBI chr 3:34,640,929...34,647,023
Ensembl chr 3:34,640,931...34,647,027 		JBrowse link
G Tp53 tumor protein p53 increases expression
decreases response to substance
multiple interactions
affects localization 		ISO
EXP 		triptolide results in increased expression of TRP53 mRNA; triptolide results in increased expression of TRP53 protein
TRP53 gene mutant form results in decreased susceptibility to triptolide
triptolide results in increased expression of TP53 mRNA; triptolide results in increased expression of TP53 protein; triptolide results in increased expression of TP53 protein modified form
pifithrin inhibits the reaction [triptolide results in increased expression of and results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [triptolide results in increased expression of TP53 protein modified form]; pifithrin inhibits the reaction [triptolide results in increased expression of TP53 protein]; triptolide results in increased expression of and results in increased phosphorylation of TP53 protein
triptolide results in increased expression of and results in increased phosphorylation of TRP53 protein; TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in decreased expression of BCL2L1 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased cleavage of CASP3 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAK1 protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of BAX protein]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased expression of CASP9 protein modified form]; TRP53 gene mutant form inhibits the reaction [triptolide results in increased secretion of TNNI3 protein]; TRP53 protein affects the reaction [triptolide results in decreased expression of RELA protein]; TRP53 protein affects the reaction [triptolide results in decreased expression of SLC2A1 protein]; TRP53 protein affects the reaction [triptolide results in decreased expression of SLC2A4 protein]; TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of IKBKB protein]; TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of NFKBIA protein]; TRP53 protein affects the reaction [triptolide results in increased expression of and results in increased phosphorylation of TRP53 protein]
triptolide affects the localization of TP53 protein
NFE2L2 protein inhibits the reaction [triptolide results in increased expression of TP53 protein]; sulforaphane inhibits the reaction [triptolide results in increased expression of TP53 protein]; TP53 protein affects the reaction [triptolide results in increased cleavage of CASP3 protein]; triptolide affects the reaction [NFE2L2 protein binds to TP53 protein]; triptolide results in increased acetylation of and results in increased phosphorylation of TP53 protein; triptolide results in increased expression of and affects the localization of TP53 protein
triptolide affects the localization of TRP53 protein 		CTD PMID:26990902 PMID:30009776 PMID:31618665 PMID:32835833 PMID:36990132 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tph1 tryptophan hydroxylase 1 multiple interactions ISO triptolide inhibits the reaction [Allura Red AC Dye results in increased expression of TPH1 mRNA] CTD PMID:36539404 NCBI chr 1:106,293,695...106,314,628
Ensembl chr 1:106,085,953...106,312,484 		JBrowse link
G Tram1 translocation associated membrane protein 1 increases expression EXP triptolide results in increased expression of TRAM1 protein CTD PMID:32519852 NCBI chr 5:10,425,710...10,450,669
Ensembl chr 5:10,425,633...10,470,056 		JBrowse link
G Trappc13 trafficking protein particle complex subunit 13 increases expression EXP triptolide results in increased expression of TRAPPC13 protein CTD PMID:32519852 NCBI chr 2:37,004,288...37,035,837
Ensembl chr 2:37,002,976...37,035,820 		JBrowse link
G Trappc2 trafficking protein particle complex subunit 2 increases expression EXP
ISO 		triptolide results in increased expression of TRAPPC2 protein
triptolide results in increased expression of TRAPPC2 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr  X:31,617,107...31,647,035
Ensembl chr  X:31,635,706...31,641,443 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO triptolide results in decreased expression of TRIB3 mRNA CTD PMID:32835833 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Trim17 tripartite motif-containing 17 increases expression ISO triptolide results in increased expression of TRIM17 mRNA CTD PMID:32835833 NCBI chr10:44,242,688...44,250,504
Ensembl chr10:44,240,184...44,250,494 		JBrowse link
G Trim6 tripartite motif containing 6 increases expression ISO triptolide results in increased expression of TRIM6 mRNA CTD PMID:32835833 NCBI chr 1:168,095,619...168,108,809
Ensembl chr 1:168,095,564...168,109,719 		JBrowse link
G Trim69 tripartite motif-containing 69 increases expression ISO triptolide results in increased expression of TRIM69 mRNA CTD PMID:32835833 NCBI chr 3:129,565,060...129,585,629
Ensembl chr 3:129,564,934...129,585,629 		JBrowse link
G Trim72 tripartite motif containing 72 increases expression ISO triptolide results in increased expression of TRIM72 mRNA CTD PMID:32835833 NCBI chr 1:192,044,220...192,052,080
Ensembl chr 1:192,044,179...192,052,073 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 increases expression EXP triptolide results in increased expression of TRIP10 mRNA CTD PMID:23639586 NCBI chr 9:2,219,695...2,234,771
Ensembl chr 9:2,220,658...2,235,027 		JBrowse link
G Trmt10a tRNA methyltransferase 10A increases expression ISO triptolide results in increased expression of TRMT10A mRNA CTD PMID:32835833 NCBI chr 2:229,342,853...229,357,573
Ensembl chr 2:229,342,864...229,360,108 		JBrowse link
G Trmt2a tRNA methyltransferase 2 homolog A increases expression ISO triptolide results in increased expression of TRMT2A mRNA CTD PMID:32835833 NCBI chr11:96,241,998...96,246,719
Ensembl chr11:96,242,001...96,246,609 		JBrowse link
G Trmt61a tRNA methyltransferase 61A increases expression ISO triptolide results in increased expression of TRMT61A mRNA CTD PMID:32835833 NCBI chr 6:136,558,417...136,564,411
Ensembl chr 6:136,558,391...136,564,410 		JBrowse link
G Tspan10 tetraspanin 10 increases expression ISO triptolide results in increased expression of TSPAN10 mRNA CTD PMID:32835833 NCBI chr10:106,213,672...106,219,951
Ensembl chr10:106,214,208...106,219,085 		JBrowse link
G Tsr2 TSR2, ribosome maturation factor increases expression EXP triptolide results in increased expression of TSR2 protein CTD PMID:32519852 NCBI chr  X:23,507,141...23,515,711
Ensembl chr  X:23,507,142...23,515,659 		JBrowse link
G Tssk1b testis-specific serine kinase 1B increases expression ISO triptolide results in increased expression of TSSK1 mRNA CTD PMID:32835833 NCBI chr11:96,595,216...96,596,639
Ensembl chr11:96,576,866...96,598,715 		JBrowse link
G Tssk4 testis-specific serine kinase 4 increases expression ISO triptolide results in increased expression of TSSK4 mRNA CTD PMID:32835833 NCBI chr15:33,108,248...33,114,083
Ensembl chr15:33,111,734...33,114,083 		JBrowse link
G Ttc12 tetratricopeptide repeat domain 12 increases expression EXP triptolide results in increased expression of TTC12 protein CTD PMID:32519852 NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:58,696,385...58,742,717 		JBrowse link
G Ttc16 tetratricopeptide repeat domain 16 increases expression ISO triptolide results in increased expression of TTC16 mRNA CTD PMID:32835833 NCBI chr 3:36,450,271...36,462,590
Ensembl chr 3:36,446,272...36,462,368 		JBrowse link
G Ttc39d tetratricopeptide repeat domain 39D increases expression EXP triptolide results in increased expression of TTC39D protein CTD PMID:32519852 NCBI chr 6:20,554,991...20,563,753
Ensembl chr 6:20,554,991...20,563,753 		JBrowse link
G Ttk Ttk protein kinase increases expression EXP triptolide results in increased expression of TTK mRNA CTD PMID:23639586 NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664 		JBrowse link
G Tubal3 tubulin, alpha-like 3 increases expression EXP triptolide results in increased expression of TUBAL3 protein CTD PMID:32519852 NCBI chr17:71,233,194...71,245,297
Ensembl chr17:71,232,851...71,245,337 		JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression ISO triptolide results in increased expression of TUBB6 mRNA CTD PMID:32835833 NCBI chr18:63,213,287...63,222,926
Ensembl chr18:63,213,279...63,224,303 		JBrowse link
G Txn1 thioredoxin 1 multiple interactions
decreases expression 		ISO NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein] CTD PMID:30394310 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnip thioredoxin interacting protein increases expression
multiple interactions 		ISO triptolide results in increased expression of TXNIP protein
NOTCH1 protein modified form inhibits the reaction [triptolide results in increased expression of TXNIP protein] 		CTD PMID:30394310 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP
ISO 		triptolide results in increased expression of TXNRD1 protein
triptolide results in increased expression of TXNRD1 mRNA 		CTD PMID:32519852 PMID:32835833 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tyk2 tyrosine kinase 2 increases expression EXP triptolide results in increased expression of TYK2 protein CTD PMID:32519852 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:27,916,496...27,943,278 		JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 increases expression EXP triptolide results in increased expression of UBA7 protein CTD PMID:32519852 NCBI chr 8:117,543,902...117,552,709
Ensembl chr 8:117,543,957...117,556,142 		JBrowse link
G Ube2o ubiquitin-conjugating enzyme E2O increases expression ISO triptolide results in increased expression of UBE2O mRNA CTD PMID:32835833 NCBI chr10:102,264,418...102,311,578
Ensembl chr10:102,264,418...102,311,549 		JBrowse link
G Ubxn1 UBX domain protein 1 decreases expression EXP triptolide results in decreased expression of UBXN1 protein CTD PMID:32519852 NCBI chr 1:215,194,418...215,198,343
Ensembl chr 1:215,174,216...215,198,343 		JBrowse link
G Ubxn4 UBX domain protein 4 decreases expression EXP triptolide results in decreased expression of UBXN4 protein CTD PMID:32519852 NCBI chr13:42,292,346...42,324,928
Ensembl chr13:42,292,528...42,326,143 		JBrowse link
G Ubxn8 UBX domain protein 8 increases expression EXP triptolide results in increased expression of UBXN8 protein CTD PMID:32519852 NCBI chr16:65,239,149...65,260,743
Ensembl chr16:65,240,062...65,260,639 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 decreases expression ISO triptolide results in decreased expression of UGT1A5 mRNA CTD PMID:32835833 NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt3a1 UDP glycosyltransferase family 3 member A1 decreases expression ISO triptolide results in decreased expression of UGT3A1 mRNA CTD PMID:32835833 NCBI chr 2:60,062,257...60,077,354
Ensembl chr 2:60,061,775...60,077,354 		JBrowse link
G Unc5b unc-5 netrin receptor B increases expression ISO triptolide results in increased expression of UNC5B mRNA CTD PMID:32835833 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:29,240,650...29,307,270 		JBrowse link
G Upp1 uridine phosphorylase 1 increases expression EXP triptolide results in increased expression of UPP1 protein CTD PMID:32519852 NCBI chr14:88,023,155...88,043,036
Ensembl chr14:88,023,351...88,043,034 		JBrowse link
G Upp2 uridine phosphorylase 2 decreases expression ISO triptolide results in decreased expression of UPP2 mRNA CTD PMID:32835833 NCBI chr 3:63,681,671...63,726,194
Ensembl chr 3:63,681,826...63,726,191 		JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X increases expression EXP triptolide results in increased expression of UQCR10 protein CTD PMID:32519852 NCBI chr14:83,789,657...83,791,914
Ensembl chr14:83,789,658...83,791,914 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression ISO triptolide results in decreased expression of UQCRC1 mRNA CTD PMID:29723566 NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 decreases expression
multiple interactions 		EXP
ISO 		triptolide results in decreased expression of UQCRC2 mRNA; triptolide results in decreased expression of UQCRC2 protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]] 		CTD PMID:36436616 NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946 		JBrowse link
G Urb1 URB1 ribosome biogenesis homolog increases expression ISO triptolide results in increased expression of URB1 mRNA CTD PMID:32835833 NCBI chr11:43,490,633...43,551,398
Ensembl chr11:43,490,633...43,551,767 		JBrowse link
G Uroc1 urocanate hydratase 1 decreases expression ISO triptolide results in decreased expression of UROC1 mRNA CTD PMID:32835833 NCBI chr 4:124,402,119...124,433,787
Ensembl chr 4:124,402,156...124,434,212 		JBrowse link
G Usp11 ubiquitin specific peptidase 11 increases expression ISO triptolide results in increased expression of USP11 mRNA CTD PMID:32835833 NCBI chr  X:4,026,865...4,043,036 JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO triptolide results in increased expression of USP36 mRNA CTD PMID:32835833 NCBI chr10:103,995,970...104,027,492
Ensembl chr10:103,995,970...104,023,450 		JBrowse link
G Usp39 ubiquitin specific peptidase 39 increases expression EXP triptolide results in increased expression of USP39 protein CTD PMID:32519852 NCBI chr 4:105,932,140...105,964,551
Ensembl chr 4:105,932,140...105,964,551 		JBrowse link
G Usp40 ubiquitin specific peptidase 40 increases expression EXP triptolide results in increased expression of USP40 protein CTD PMID:32519852 NCBI chr 9:96,055,741...96,126,766
Ensembl chr 9:96,055,741...96,126,721 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 increases expression ISO triptolide results in increased expression of USP47 mRNA CTD PMID:32835833 NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:175,586,723...175,669,904 		JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 increases expression ISO triptolide results in increased expression of USPL1 mRNA CTD PMID:32835833 NCBI chr12:10,859,764...10,886,761
Ensembl chr12:10,859,764...10,886,744 		JBrowse link
G Ust4r integral membrane transport protein UST4r increases expression EXP triptolide results in increased expression of UST4R protein CTD PMID:32519852 NCBI chr 1:214,501,347...214,571,852
Ensembl chr 1:214,501,347...214,571,832 		JBrowse link
G Vcan versican increases expression EXP triptolide results in increased expression of VCAN protein CTD PMID:32519852 NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955 		JBrowse link
G Vdac3 voltage-dependent anion channel 3 increases expression EXP triptolide results in increased expression of VDAC3 protein CTD PMID:32519852 NCBI chr16:76,137,489...76,153,933
Ensembl chr16:76,137,504...76,155,304 		JBrowse link
G Vps37b VPS37B subunit of ESCRT-I increases expression ISO triptolide results in increased expression of VPS37B mRNA CTD PMID:32835833 NCBI chr12:38,220,973...38,249,935
Ensembl chr12:38,220,959...38,249,935 		JBrowse link
G Vps53 VPS53 subunit of GARP complex increases expression EXP triptolide results in increased expression of VPS53 protein CTD PMID:32519852 NCBI chr10:61,418,076...61,536,912
Ensembl chr10:61,418,076...61,531,760 		JBrowse link
G Vtn vitronectin increases expression EXP triptolide results in increased expression of VTN protein CTD PMID:32519852 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860 		JBrowse link
G Vxn vexin increases expression ISO triptolide results in increased expression of VXN mRNA CTD PMID:32835833 NCBI chr 5:14,442,040...14,467,500
Ensembl chr 5:14,442,040...14,467,500 		JBrowse link
G Wdr19 WD repeat domain 19 decreases expression ISO triptolide results in decreased expression of WDR19 mRNA CTD PMID:32835833 NCBI chr14:43,396,130...43,460,012
Ensembl chr14:43,397,835...43,459,939 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 decreases expression ISO triptolide results in decreased expression of WIPI1 mRNA CTD PMID:32835833 NCBI chr10:95,042,451...95,079,679
Ensembl chr10:95,042,441...95,079,293 		JBrowse link
G Wnt9b Wnt family member 9B increases expression ISO triptolide results in increased expression of WNT9B mRNA CTD PMID:32835833 NCBI chr10:89,135,362...89,157,065
Ensembl chr10:89,135,363...89,157,065 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO XDH protein inhibits the reaction [bergenin inhibits the reaction [triptolide results in decreased activity of CAT protein]] CTD PMID:38735593 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions
decreases expression 		ISO [Idarubicin co-treated with triptolide] affects the expression of XIAP protein
triptolide results in decreased expression of XIAP protein
[triptolide co-treated with FASL protein] results in decreased expression of XIAP mRNA; [triptolide co-treated with FASL protein] results in decreased expression of XIAP protein; [triptolide co-treated with FASL protein] results in increased expression of XIAP mRNA; CASP3 inhibits the reaction [[triptolide co-treated with FASL protein] results in increased cleavage of XIAP protein]; MIR137 promotes the reaction [[triptolide co-treated with FASL protein] results in decreased expression of XIAP protein] 		CTD PMID:18922616 PMID:27022166 PMID:37944651 NCBI chr  X:125,756,107...125,803,979
Ensembl chr  X:125,737,971...125,803,978 		JBrowse link
G Xist X inactive specific transcript increases expression ISO triptolide results in increased expression of XIST mRNA CTD PMID:32835833 NCBI chr  X:72,540,753...72,558,266 JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 increases expression EXP triptolide results in increased expression of XPNPEP2 protein CTD PMID:32519852 NCBI chr  X:132,165,696...132,194,937
Ensembl chr  X:132,165,701...132,195,126 		JBrowse link
G Yipf5 Yip1 domain family, member 5 decreases expression EXP triptolide results in decreased expression of YIPF5 protein CTD PMID:32519852 NCBI chr18:32,374,913...32,388,046
Ensembl chr18:32,374,916...32,408,738 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma increases expression EXP triptolide results in increased expression of YWHAG mRNA CTD PMID:23639586 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta increases expression EXP triptolide results in increased expression of YWHAH mRNA CTD PMID:23639586 NCBI chr14:81,920,819...81,930,202
Ensembl chr14:81,920,590...81,947,930 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression EXP triptolide results in increased expression of YWHAQ mRNA CTD PMID:23639586 NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875 		JBrowse link
G Zbtb21 zinc finger and BTB domain containing 21 increases expression ISO triptolide results in increased expression of ZBTB21 mRNA CTD PMID:32835833 NCBI chr11:50,781,697...50,796,399
Ensembl chr11:50,781,099...50,796,560 		JBrowse link
G Zc2hc1a zinc finger, C2HC-type containing 1A increases expression ISO triptolide results in increased expression of ZC2HC1A mRNA CTD PMID:32835833 NCBI chr 2:96,194,665...96,231,957
Ensembl chr 2:96,194,671...96,232,288 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 increases expression EXP triptolide results in increased expression of ZC3HAV1 protein CTD PMID:32519852 NCBI chr 4:67,979,055...68,029,353
Ensembl chr 4:67,979,055...68,029,353 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression ISO triptolide results in increased expression of ZFAND2A mRNA CTD PMID:32835833 NCBI chr12:20,275,435...20,286,513
Ensembl chr12:20,275,450...20,286,513 		JBrowse link
G Zfand4 zinc finger AN1-type containing 4 decreases expression ISO triptolide results in decreased expression of ZFAND4 mRNA CTD PMID:32835833 NCBI chr 4:150,999,821...151,071,942
Ensembl chr 4:150,999,836...151,072,055 		JBrowse link
G Zfp143 zinc finger protein 143 increases expression ISO triptolide results in increased expression of ZFP143 mRNA CTD PMID:32835833 NCBI chr 1:173,543,810...173,579,667
Ensembl chr 1:173,543,863...173,579,660 		JBrowse link
G Zfp593 zinc finger protein 593 increases expression ISO triptolide results in increased expression of ZFP593 mRNA CTD PMID:32835833 NCBI chr 5:151,746,396...151,748,724
Ensembl chr 5:151,746,396...151,748,891 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO triptolide results in increased expression of ZMAT3 mRNA CTD PMID:32835833 NCBI chr 2:117,034,517...117,066,141
Ensembl chr 2:117,034,517...117,065,294 		JBrowse link
G Zmym6 zinc finger MYM-type containing 6 increases expression ISO triptolide results in increased expression of ZMYM6 mRNA CTD PMID:32835833 NCBI chr 5:144,680,819...144,728,805
Ensembl chr 5:144,681,197...144,728,803 		JBrowse link
G Zmynd12 zinc finger, MYND-type containing 12 increases expression ISO triptolide results in increased expression of ZMYND12 mRNA CTD PMID:32835833 NCBI chr 5:138,312,257...138,345,269
Ensembl chr 5:138,312,315...138,345,263 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20841
    role 20801
      application 20602
        antispermatogenic agent 1179
          Triptolide 1137
Path 2
Term Annotations click to browse term
  CHEBI ontology 20841
    subatomic particle 20839
      composite particle 20839
        hadron 20839
          baryon 20839
            nucleon 20839
              atomic nucleus 20839
                atom 20839
                  main group element atom 20762
                    p-block element atom 20786
                      carbon group element atom 20695
                        carbon atom 20690
                          organic molecular entity 20690
                            heteroorganic entity 20202
                              organochalcogen compound 19889
                                organooxygen compound 19791
                                  carbon oxoacid 19142
                                    carboxylic acid 19139
                                      carboacyl group 18069
                                        univalent carboacyl group 18069
                                          carbamoyl group 17904
                                            carboxamide 17904
                                              lactam 8429
                                                gamma-lactam 6672
                                                  Triptolide 1137
paths to the root