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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Tripelennamine
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Accession:CHEBI:9741 term browser browse the term
Definition:An aromatic amine that has formula C16H21N3.
Synonyms:related_synonym: Formula=C16H21N3;   InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3;   InChIKey=UFLGIAIHIAPJJC-UHFFFAOYSA-N;   SMILES=CN(C)CCN(Cc1ccccc1)c1ccccn1;   pyribenzamin;   pyribenzamine;   pyrinamine base;   tripelenamine;   tripelennamin;   tripelennamine HCl;   tripelennamine citrate;   tripelennamine hydrochloride
 xref: CAS:91-81-6;   Drug_Central:2762;   HMDB:HMDB0014930;   KEGG:C07180;   KEGG:D08645;   LINCS:LSM-3271
 xref_mesh: MESH:D014309


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Tripelennamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity
multiple interactions		 ISO Tripelennamine results in decreased activity of BCHE protein
Acetylcholine inhibits the reaction [Tripelennamine results in decreased activity of BCHE protein]; Protons affects the reaction [Tripelennamine results in decreased activity of BCHE protein]		 CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions EXP [Tripelennamine binds to and results in decreased activity of HRH1 protein] which affects the susceptibility to Histamine CTD PMID:12832840 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Tripelennamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tripelennamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        NMR chemical shift reference compound 17936
          ammonia 17795
            organic amino compound 17795
              aromatic amine 15398
                Tripelennamine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    main group molecular entity 19759
                      s-block molecular entity 19628
                        hydrogen molecular entity 19614
                          hydrides 19087
                            inorganic hydride 18091
                              pnictogen hydride 18080
                                nitrogen hydride 17987
                                  azane 17796
                                    ammonia 17795
                                      organic amino compound 17795
                                        aromatic amine 15398
                                          Tripelennamine 4
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