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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Tripelennamine
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Accession:CHEBI:9741 term browser browse the term
Definition:An aromatic amine that has formula C16H21N3.
Synonyms:related_synonym: Formula=C16H21N3;   InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3;   InChIKey=UFLGIAIHIAPJJC-UHFFFAOYSA-N;   SMILES=CN(C)CCN(Cc1ccccc1)c1ccccn1;   pyribenzamin;   pyribenzamine;   pyrinamine base;   tripelenamine;   tripelennamin;   tripelennamine HCl;   tripelennamine citrate;   tripelennamine hydrochloride
 xref: CAS:91-81-6;   Drug_Central:2762;   HMDB:HMDB0014930;   KEGG:C07180;   KEGG:D08645;   LINCS:LSM-3271
 xref_mesh: MESH:D014309



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Tripelennamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity
multiple interactions
ISO Tripelennamine results in decreased activity of BCHE protein
Acetylcholine inhibits the reaction [Tripelennamine results in decreased activity of BCHE protein]; Protons affects the reaction [Tripelennamine results in decreased activity of BCHE protein]
CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions EXP [Tripelennamine binds to and results in decreased activity of HRH1 protein] which affects the susceptibility to Histamine CTD PMID:12832840 NCBI chr 4:147,564,781...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Tripelennamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Tripelennamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      chemical role 19341
        base 17287
          Bronsted base 17287
            organic amino compound 17279
              aromatic amine 13708
                Tripelennamine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    main group molecular entity 19720
                      s-block molecular entity 19502
                        hydrogen molecular entity 19495
                          hydrides 18855
                            inorganic hydride 17694
                              pnictogen hydride 17675
                                nitrogen hydride 17547
                                  azane 17280
                                    ammonia 17279
                                      organic amino compound 17279
                                        aromatic amine 13708
                                          Tripelennamine 4
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