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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:9738 term browser browse the term
Definition:A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
Synonyms:exact_synonym: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine
 related_synonym: 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine;   5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;   5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine;   Formula=C20H26N2;   InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3;   InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N;   RP-7162;   SMILES=CC(CN(C)C)CN1c2ccccc2CCc2ccccc12;   Sapilent;   Trimeprimine;   beta-methylimipramine;   trimeproprimine
 xref: Beilstein:1321466;   CAS:739-71-9;   DrugBank:DB00726;   Drug_Central:2758;   HMDB:HMDB0014864;   KEGG:D00394;   LINCS:LSM-1371
 xref_mesh: MESH:D014299
 xref: PMID:22642681;   PMID:25178259;   Patent:CN103893187;   Reaxys:1321466;   Wikipedia:Trimipramine

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trimipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Trimipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    role 20009
      biological role 20008
        xenobiotic 18633
          trimipramine 1
            trimipramine maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic molecule 19819
                              organic cyclic compound 19581
                                organic heterocyclic compound 18804
                                  organic heteropolycyclic compound 18274
                                    organic heterotricyclic compound 15606
                                      mancude organic heterotricyclic parent 361
                                        5H-dibenzo[b,f]azepine 133
                                          imipramine 133
                                            trimipramine 1
                                              trimipramine maleate 0
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