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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimipramine
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Accession:CHEBI:9738 term browser browse the term
Definition:A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
Synonyms:exact_synonym: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine
 related_synonym: 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine;   5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;   5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine;   Formula=C20H26N2;   InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3;   InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N;   RP-7162;   SMILES=CC(CN(C)C)CN1c2ccccc2CCc2ccccc12;   Sapilent;   Trimeprimine;   beta-methylimipramine;   trimeproprimine
 xref: Beilstein:1321466;   CAS:739-71-9;   DrugBank:DB00726;   Drug_Central:2758;   HMDB:HMDB0014864;   KEGG:D00394;   LINCS:LSM-1371
 xref_mesh: MESH:D014299
 xref: PMID:22642681;   PMID:25178259;   Patent:CN103893187;   Reaxys:1321466;   Wikipedia:Trimipramine


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trimipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Trimipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    role 19894
      biological role 19864
        xenobiotic 18740
          trimipramine 1
            trimipramine maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19805
                        carbon atom 19802
                          organic molecular entity 19775
                            organic molecule 19755
                              organic cyclic compound 19545
                                organic heterocyclic compound 18906
                                  organic heteropolycyclic compound 18314
                                    organic heterotricyclic compound 15658
                                      mancude organic heterotricyclic parent 375
                                        5H-dibenzo[b,f]azepine 136
                                          imipramine 136
                                            trimipramine 1
                                              trimipramine maleate 0
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