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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:trimipramine
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Accession:CHEBI:9738 term browser browse the term
Definition:A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.
Synonyms:exact_synonym: 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N,2-trimethylpropan-1-amine
 related_synonym: 10,11-dihydro-N,N,beta-trimethyl-5H-dibenz[b,f]azepine-5-propanamine;   5-(gamma-dimethylamino-beta-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;   5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine;   Formula=C20H26N2;   InChI=1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3;   InChIKey=ZSCDBOWYZJWBIY-UHFFFAOYSA-N;   RP-7162;   SMILES=CC(CN(C)C)CN1c2ccccc2CCc2ccccc12;   Sapilent;   Trimeprimine;   beta-methylimipramine;   trimeproprimine
 xref: Beilstein:1321466;   CAS:739-71-9;   DrugBank:DB00726;   Drug_Central:2758;   HMDB:HMDB0014864;   KEGG:D00394;   LINCS:LSM-1371
 xref_mesh: MESH:D014299
 xref: PMID:22642681;   PMID:25178259;   Patent:CN103893187;   Reaxys:1321466;   Wikipedia:Trimipramine


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trimipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Trimipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19908
    role 19883
      biological role 19881
        xenobiotic 18772
          trimipramine 1
            trimipramine maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19908
    subatomic particle 19906
      composite particle 19906
        hadron 19906
          baryon 19906
            nucleon 19906
              atomic nucleus 19906
                atom 19906
                  main group element atom 19853
                    p-block element atom 19853
                      carbon group element atom 19799
                        carbon atom 19794
                          organic molecular entity 19794
                            organic molecule 19751
                              organic cyclic compound 19559
                                organic heterocyclic compound 18896
                                  organic heteropolycyclic compound 18317
                                    organic heterotricyclic compound 15654
                                      mancude organic heterotricyclic parent 373
                                        5H-dibenzo[b,f]azepine 134
                                          imipramine 134
                                            trimipramine 1
                                              trimipramine maleate 0
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