Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Trihexyphenidyl
go back to main search page
Accession:CHEBI:9720 term browser browse the term
Definition:An amine that has formula C20H31NO.
Synonyms:related_synonym: Formula=C20H31NO;   InChI=1S/C20H31NO/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;   InChIKey=HWHLPVGTWGOCJO-UHFFFAOYSA-N;   SMILES=OC(CCN1CCCCC1)(C1CCCCC1)c1ccccc1;   benzhexol;   benzhexol HCl;   benzhexol hydrochloride;   trihexyphenidyl HCl;   trihexyphenidyl hydrochloride
 xref: CAS:144-11-6;   Drug_Central:2745;   HMDB:HMDB0014520;   KEGG:C07171;   KEGG:D08638;   LINCS:LSM-5060
 xref_mesh: MESH:D014282


show annotations for term's descendants           Sort by:
 
Trihexyphenidyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E increases response to substance ISO APOE gene polymorphism results in increased susceptibility to Trihexyphenidyl CTD PMID:18239197 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO Trihexyphenidyl results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Ereg epiregulin increases expression ISO Trihexyphenidyl results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Trihexyphenidyl results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Trihexyphenidyl results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il24 interleukin 24 increases expression ISO Trihexyphenidyl results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO Trihexyphenidyl results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO Trihexyphenidyl results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Trihexyphenidyl results in increased expression of PTGS2 mRNA CTD PMID:32816093 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Trihexyphenidyl inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Trihexyphenidyl results in increased expression of SLC7A11 mRNA CTD PMID:32816093 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Trihexyphenidyl results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Trihexyphenidyl results in increased expression of TNFAIP6 mRNA CTD PMID:32816093 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19786
    role 19732
      application 19423
        refrigerant 17481
          ammonia 17020
            organic amino compound 17019
              amine 7825
                Trihexyphenidyl 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19786
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19675
                    main group molecular entity 19675
                      s-block molecular entity 19443
                        hydrogen molecular entity 19439
                          hydrides 18763
                            inorganic hydride 17484
                              pnictogen hydride 17461
                                nitrogen hydride 17315
                                  azane 17021
                                    ammonia 17020
                                      organic amino compound 17019
                                        amine 7825
                                          Trihexyphenidyl 13
paths to the root