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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:triforine
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Accession:CHEBI:9715 term browser browse the term
Definition:A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.
Synonyms:exact_synonym: N,N'-[piperazine-1,4-diylbis(2,2,2-trichloroethane-1,1-diyl)]diformamide
 related_synonym: 1,4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine;   1,4-Bis(2,2,2-trichloro-1-formamidoethyl)piperazine;   Biformylchlorazin;   Formula=C10H14Cl6N4O2;   Funginex;   InChI=1S/C10H14Cl6N4O2/c11-9(12,13)7(17-5-21)19-1-2-20(4-3-19)8(18-6-22)10(14,15)16/h5-8H,1-4H2,(H,17,21)(H,18,22);   InChIKey=RROQIUMZODEXOR-UHFFFAOYSA-N;   N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene))bisformamide;   N,N'-(Piperazine-1,4-diylbis((trichloromethyl)methylene))diformamide;   SMILES=ClC(Cl)(Cl)C(NC=O)N1CCN(CC1)C(NC=O)C(Cl)(Cl)Cl
 xref: CAS:26644-46-2;   KEGG:C10960
 xref_mesh: MESH:C012591
 xref: PMID:1002932;   PMID:1267484;   PMID:15052559;   PMID:24122157;   PMID:2471555;   PMID:597629;   PMID:680740;   PMID:7821004;   PMID:890154;   PPDB:669;   Patent:EP0031454;   Patent:US3975527;   Pesticides:triforine;   Reaxys:626358


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triforine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO triforine binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19908
    role 19883
      biological role 19881
        aetiopathogenetic role 19215
          allergen 17674
            triforine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19908
    subatomic particle 19906
      composite particle 19906
        hadron 19906
          baryon 19906
            nucleon 19906
              atomic nucleus 19906
                atom 19906
                  main group element atom 19853
                    p-block element atom 19853
                      carbon group element atom 19799
                        carbon atom 19794
                          organic molecular entity 19794
                            organic group 18960
                              organic divalent group 18941
                                organodiyl group 18941
                                  carbonyl group 18893
                                    carbonyl compound 18893
                                      carboxylic acid 18614
                                        carboacyl group 17709
                                          univalent carboacyl group 17709
                                            carbamoyl group 17556
                                              carboxamide 17556
                                                formamides 1810
                                                  triforine 1
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