Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:triforine
go back to main search page
Accession:CHEBI:9715 term browser browse the term
Definition:A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.
Synonyms:exact_synonym: N,N'-[piperazine-1,4-diylbis(2,2,2-trichloroethane-1,1-diyl)]diformamide
 related_synonym: 1,4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine;   1,4-Bis(2,2,2-trichloro-1-formamidoethyl)piperazine;   Biformylchlorazin;   Formula=C10H14Cl6N4O2;   Funginex;   InChI=1S/C10H14Cl6N4O2/c11-9(12,13)7(17-5-21)19-1-2-20(4-3-19)8(18-6-22)10(14,15)16/h5-8H,1-4H2,(H,17,21)(H,18,22);   InChIKey=RROQIUMZODEXOR-UHFFFAOYSA-N;   N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene))bisformamide;   N,N'-(Piperazine-1,4-diylbis((trichloromethyl)methylene))diformamide;   SMILES=ClC(Cl)(Cl)C(NC=O)N1CCN(CC1)C(NC=O)C(Cl)(Cl)Cl
 xref: CAS:26644-46-2;   KEGG:C10960
 xref_mesh: MESH:C012591
 xref: PMID:1002932;   PMID:1267484;   PMID:15052559;   PMID:24122157;   PMID:2471555;   PMID:597629;   PMID:680740;   PMID:7821004;   PMID:890154;   PPDB:669;   Patent:EP0031454;   Patent:US3975527;   Pesticides:triforine;   Reaxys:626358


show annotations for term's descendants           Sort by:
 
triforine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO triforine binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        aetiopathogenetic role 18936
          allergen 16919
            triforine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        carboacyl group 17346
                                          univalent carboacyl group 17346
                                            carbamoyl group 17132
                                              carboxamide 17132
                                                formamides 1347
                                                  triforine 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.