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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:thapsigargin
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Accession:CHEBI:9516 term browser browse the term
Definition:An organic heterotricyclic compound that is a hexa-oxygenated 6,7-guaianolide isolated fron the roots of Thapsia garganica L., Apiaceae. A potent skin irritant, it is used in traditional medicine as a counter-irritant. Thapsigargin inhibits Ca(2+)-transporting ATPase mediated uptake of calcium ions into sarcoplasmic reticulum and is used in experimentation examining the impacts of increasing cytosolic calcium concentrations.
Synonyms:related_synonym: (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl octanoate;   Formula=C34H50O12;   InChI=1S/C34H50O12/c1-9-12-13-14-15-17-24(37)43-28-26-25(20(5)27(28)44-30(38)19(4)11-3)29-34(41,33(8,40)31(39)45-29)22(42-23(36)16-10-2)18-32(26,7)46-21(6)35/h11,22,26-29,40-41H,9-10,12-18H2,1-8H3/b19-11-/t22-,26+,27-,28-,29-,32-,33+,34+/m0/s1;   InChIKey=IXFPJGBNCFXKPI-FSIHEZPISA-N;   SMILES=[H][C@@]1(OC(=O)C(\\C)=C/C)[C@@H](OC(=O)CCCCCCC)[C@@]2([H])C(=C1C)[C@]1([H])OC(=O)[C@@](C)(O)[C@@]1(O)[C@H](C[C@]2(C)OC(C)=O)OC(=O)CCC;   Tg;   octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester;   thapsigargine
 alt_id: CHEBI:363811;   CHEBI:45970
 xref: Beilstein:4649293;   CAS:67526-95-8;   KEGG:C09561;   KNApSAcK:C00003375;   LIPID_MAPS_instance:LMPR0103410001
 xref_mesh: MESH:D019284
 xref: PDBeChem:TG1;   PMID:10477042;   PMID:12410314;   PMID:16874404;   PMID:17825049;   PMID:20357004;   PMID:24598360;   PMID:9014219;   Reaxys:4649293;   Wikipedia:Thapsigargin


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thapsigargin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases expression ISO Thapsigargin results in increased expression of AARS protein CTD PMID:24648495 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 increases expression ISO Thapsigargin results in increased expression of ACAD11 mRNA CTD PMID:22378314 NCBI chr 8:112,594,758...112,676,275
Ensembl chr 8:112,594,691...112,676,280
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression ISO Thapsigargin results in decreased expression of ACAD9 mRNA CTD PMID:22378314 NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain increases expression ISO Thapsigargin results in increased expression of ACADVL mRNA CTD PMID:22378314 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression ISO Thapsigargin results in decreased expression of ACAT2 mRNA CTD PMID:22378314 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 increases expression ISO Thapsigargin results in increased expression of ACBD3 mRNA CTD PMID:22378314 NCBI chr13:99,004,942...99,035,520
Ensembl chr13:99,004,942...99,035,519
JBrowse link
G Ackr1 atypical chemokine receptor 1 increases expression ISO Thapsigargin results in increased expression of ACKR1 mRNA CTD PMID:22378314 NCBI chr13:91,827,310...91,828,875 JBrowse link
G Acly ATP citrate lyase increases expression ISO Thapsigargin results in increased expression of ACLY protein CTD PMID:24648495 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco2 aconitase 2 increases expression ISO Thapsigargin results in increased expression of ACO2 protein CTD PMID:24648495 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot13 acyl-CoA thioesterase 13 decreases expression ISO Thapsigargin results in decreased expression of ACOT13 mRNA CTD PMID:22378314 NCBI chr17:42,241,141...42,253,611
Ensembl chr17:42,241,159...42,253,649
JBrowse link
G Acot7 acyl-CoA thioesterase 7 decreases expression ISO Thapsigargin results in decreased expression of ACOT7 mRNA CTD PMID:22378314 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
decreases expression
ISO Thapsigargin results in increased expression of ACTA2 mRNA
Thapsigargin results in decreased expression of ACTA2 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actg1 actin, gamma 1 decreases expression ISO Thapsigargin results in decreased expression of ACTG1 mRNA CTD PMID:22378314 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Actn1 actinin, alpha 1 decreases expression ISO Thapsigargin results in decreased expression of ACTN1 mRNA CTD PMID:22378314 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Acvr1 activin A receptor type 1 increases expression ISO Thapsigargin results in increased expression of ACVR1 mRNA CTD PMID:29453283 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 decreases expression ISO Thapsigargin results in decreased expression of ADAMTS4 mRNA CTD PMID:22378314 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 decreases expression ISO Thapsigargin results in decreased expression of ADAMTS9 mRNA CTD PMID:22378314 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 increases expression ISO Thapsigargin results in increased expression of ADHFE1 mRNA CTD PMID:22378314 NCBI chr 5:9,403,194...9,429,783
Ensembl chr 5:9,403,196...9,429,859
JBrowse link
G Adi1 acireductone dioxygenase 1 decreases expression ISO Thapsigargin results in decreased expression of ADI1 protein CTD PMID:24648495 NCBI chr 6:47,940,211...47,947,173
Ensembl chr 6:47,940,183...47,947,230
JBrowse link
G Adm adrenomedullin decreases expression
increases expression
ISO Thapsigargin results in decreased expression of ADM mRNA
Thapsigargin results in increased expression of ADM mRNA
CTD PMID:20682585, PMID:22378314 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adm2 adrenomedullin 2 increases expression ISO Thapsigargin results in increased expression of ADM2 mRNA CTD PMID:22378314 NCBI chr 7:130,296,895...130,298,641
Ensembl chr 7:130,296,897...130,298,644
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] CTD PMID:10742289 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Afap1 actin filament associated protein 1 increases expression ISO Thapsigargin results in increased expression of AFAP1 protein CTD PMID:24648495 NCBI chr14:79,923,132...80,035,096
Ensembl chr14:79,919,717...79,988,110
JBrowse link
G Afdn afadin, adherens junction formation factor increases expression ISO Thapsigargin results in increased expression of AFDN protein CTD PMID:24648495 NCBI chr 1:53,713,873...53,861,918
Ensembl chr 1:53,715,693...53,802,658
JBrowse link
G Ago3 argonaute RISC catalytic component 3 multiple interactions
affects localization
ISO Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] CTD PMID:29576526 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Thapsigargin results in increased expression of AHNAK mRNA CTD PMID:19442820 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Thapsigargin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:15364539 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak2 adenylate kinase 2 decreases expression ISO Thapsigargin results in decreased expression of AK2 mRNA CTD PMID:22378314 NCBI chr 5:147,185,474...147,204,050
Ensembl chr 5:147,185,474...147,204,050
JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Thapsigargin results in decreased expression of AK3 mRNA CTD PMID:22378314 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Thapsigargin results in decreased expression of AK4 mRNA CTD PMID:22378314 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akap17a A-kinase anchoring protein 17A increases expression ISO Thapsigargin results in increased expression of AKAP17A mRNA CTD PMID:22378314 NCBI chr12:18,527,116...18,531,780
Ensembl chr12:18,526,422...18,531,161
JBrowse link
G Akap8l A-kinase anchoring protein 8 like increases expression ISO Thapsigargin results in increased expression of AKAP8L protein CTD PMID:24648495 NCBI chr 7:14,340,168...14,369,835
Ensembl chr 7:14,340,170...14,369,821
JBrowse link
G Akirin1 akirin 1 decreases expression ISO Thapsigargin results in decreased expression of AKIRIN1 protein CTD PMID:24648495 NCBI chr 5:141,415,226...141,430,627
Ensembl chr 5:141,415,075...141,430,659
JBrowse link
G Akna AT-hook transcription factor increases expression ISO Thapsigargin results in increased expression of AKNA mRNA CTD PMID:22378314 NCBI chr 5:79,184,087...79,232,370
Ensembl chr 5:79,184,088...79,222,687
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
decreases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; NRF1 protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein]; TFAM protein inhibits the reaction [Thapsigargin results in decreased phosphorylation of AKT1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Thapsigargin results in increased phosphorylation of AKT1 protein]
[Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein
Thapsigargin results in decreased expression of AKT1 protein modified form
CTD PMID:15339911, PMID:16338971, PMID:22378314, PMID:24898257, PMID:25398788 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aktip AKT interacting protein decreases expression ISO Thapsigargin results in decreased expression of AKTIP protein CTD PMID:24648495 NCBI chr19:17,290,048...17,300,054
Ensembl chr19:17,290,178...17,300,050
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Thapsigargin results in increased expression of ALCAM mRNA CTD PMID:22378314 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression ISO Thapsigargin results in increased expression of ALDH18A1 protein CTD PMID:24648495 NCBI chr 1:259,641,673...259,674,521
Ensembl chr 1:259,641,676...259,674,425
Ensembl chr 1:259,641,676...259,674,425
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Thapsigargin results in decreased expression of ALDH1A2 mRNA CTD PMID:29453283 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression ISO Thapsigargin results in decreased expression of ALDH1A3 mRNA CTD PMID:22378314 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression ISO Thapsigargin results in decreased expression of ALDH5A1 mRNA CTD PMID:22378314 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO Thapsigargin results in increased expression of ALDH6A1 mRNA CTD PMID:22378314 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Thapsigargin results in decreased expression of ALDOC mRNA CTD PMID:22378314 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alg5 ALG5, dolichyl-phosphate beta-glucosyltransferase increases expression ISO Thapsigargin results in increased expression of ALG5 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 2:143,932,242...143,946,472
Ensembl chr 2:143,932,739...143,946,466
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO 1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]; 1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]]; SB 203580 inhibits the reaction [Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein; Thapsigargin results in increased phosphorylation of and results in increased activity of ALOX5 protein CTD PMID:10779545, PMID:18218859 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alpp alkaline phosphatase, placental increases expression ISO Thapsigargin results in increased expression of ALPP mRNA CTD PMID:29453283 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Amot angiomotin decreases expression ISO Thapsigargin results in decreased expression of AMOT mRNA CTD PMID:29453283 NCBI chr  X:116,751,231...116,810,238
Ensembl chr  X:116,751,230...116,792,864
JBrowse link
G Amt aminomethyltransferase increases expression ISO Thapsigargin results in increased expression of AMT mRNA CTD PMID:22378314 NCBI chr 8:117,068,388...117,078,633
Ensembl chr 8:117,068,582...117,077,913
JBrowse link
G Angptl2 angiopoietin-like 2 decreases expression ISO Thapsigargin results in decreased expression of ANGPTL2 protein CTD PMID:24648495 NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
JBrowse link
G Ankrd10 ankyrin repeat domain 10 increases expression ISO Thapsigargin results in increased expression of ANKRD10 mRNA CTD PMID:29453283 NCBI chr16:83,205,898...83,229,147
Ensembl chr16:83,206,004...83,228,194
JBrowse link
G Ankrd17 ankyrin repeat domain 17 increases expression ISO Thapsigargin results in increased expression of ANKRD17 protein CTD PMID:24648495 NCBI chr14:19,291,025...19,431,521
Ensembl chr14:19,318,565...19,431,515
JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO Thapsigargin results in increased expression of ANTXR2 mRNA CTD PMID:22378314 NCBI chr14:13,191,716...13,331,286
Ensembl chr14:13,192,347...13,274,978
JBrowse link
G Anxa5 annexin A5 increases expression ISO Thapsigargin results in increased expression of ANXA5 mRNA CTD PMID:22378314 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 decreases expression ISO Thapsigargin results in decreased expression of AP2M1 protein CTD PMID:24648495 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 increases expression ISO Thapsigargin results in increased expression of AP3B1 protein CTD PMID:24648495 NCBI chr 2:24,022,815...24,227,522
Ensembl chr 2:24,024,791...24,226,224
JBrowse link
G Aqr aquarius intron-binding spliceosomal factor increases expression ISO Thapsigargin results in increased expression of AQR protein CTD PMID:24648495 NCBI chr 3:105,570,399...105,640,431
Ensembl chr 3:105,570,292...105,640,463
JBrowse link
G Ar androgen receptor multiple interactions ISO Thapsigargin results in increased degradation of and results in decreased expression of AR protein CTD PMID:30280407 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arcn1 archain 1 increases expression ISO Thapsigargin results in increased expression of ARCN1 mRNA CTD PMID:22378314 NCBI chr 8:49,051,257...49,075,861
Ensembl chr 8:49,051,246...49,075,892
JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression ISO Thapsigargin results in decreased expression of ARF3 mRNA CTD PMID:29453283 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arf4 ADP-ribosylation factor 4 increases expression ISO Thapsigargin results in increased expression of ARF4 mRNA CTD PMID:22378314 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Arfgap3 ADP-ribosylation factor GTPase activating protein 3 increases expression ISO Thapsigargin results in increased expression of ARFGAP3 mRNA CTD PMID:22378314 NCBI chr 7:124,149,665...124,198,298
Ensembl chr 7:124,149,751...124,198,200
JBrowse link
G Arg2 arginase 2 decreases expression ISO Thapsigargin results in decreased expression of ARG2 mRNA CTD PMID:22378314 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 increases expression ISO Thapsigargin results in increased expression of ARHGEF2 mRNA CTD PMID:22378314 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Arid4a AT-rich interaction domain 4A increases expression ISO Thapsigargin results in increased expression of ARID4A protein CTD PMID:24648495 NCBI chr 6:93,461,713...93,532,901
Ensembl chr 6:93,461,713...93,532,901
JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Thapsigargin results in increased expression of ARID4B protein CTD PMID:24648495 NCBI chr17:53,831,353...53,955,897
Ensembl chr17:53,833,023...53,915,076
JBrowse link
G Arl1 ADP-ribosylation factor like GTPase 1 increases expression ISO Thapsigargin results in increased expression of ARL1 mRNA CTD PMID:22378314 NCBI chr 7:29,282,411...29,293,455
Ensembl chr 7:29,282,305...29,293,399
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 increases expression ISO Thapsigargin results in increased expression of ARMCX1 mRNA CTD PMID:22378314 NCBI chr  X:105,535,670...105,539,575
Ensembl chr  X:105,537,602...105,539,375
Ensembl chr  X:105,537,602...105,539,375
JBrowse link
G Armcx3 armadillo repeat containing, X-linked 3 increases expression ISO Thapsigargin results in increased expression of ARMCX3 mRNA CTD PMID:22378314 NCBI chr  X:105,573,909...105,577,480
Ensembl chr  X:105,573,909...105,580,562
JBrowse link
G Arpc3 actin related protein 2/3 complex, subunit 3 increases expression ISO Thapsigargin results in increased expression of ARPC3 mRNA CTD PMID:22378314 NCBI chr12:39,653,951...39,667,817
Ensembl chr12:39,653,953...39,667,849
JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 decreases expression ISO Thapsigargin results in decreased expression of ASB5 protein CTD PMID:24648495 NCBI chr16:39,985,233...40,050,663
Ensembl chr16:39,985,234...40,025,401
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO Thapsigargin results in increased expression of ASCL1 mRNA CTD PMID:22378314 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO Thapsigargin results in decreased expression of ASF1B mRNA CTD PMID:22378314 NCBI chr19:25,077,918...25,092,491
Ensembl chr19:25,077,918...25,092,491
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 increases expression ISO Thapsigargin results in increased expression of ASGR1 mRNA CTD PMID:29453283 NCBI chr10:56,662,188...56,666,086
Ensembl chr10:56,662,242...56,666,086
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Thapsigargin results in increased expression of ASNS mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Thapsigargin results in increased expression of ASPH protein CTD PMID:24648495 NCBI chr 5:22,577,680...22,799,333
Ensembl chr 5:22,577,675...22,799,349
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of ATAD2 mRNA
Thapsigargin results in increased expression of ATAD2 protein
CTD PMID:22378314, PMID:24648495 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO
EXP
ATF3 mutant form promotes the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA]
Thapsigargin results in increased expression of ATF3 mRNA
Thapsigargin results in increased expression of ATF3 mRNA; Thapsigargin results in increased expression of ATF3 protein
CTD PMID:17332266, PMID:20022965, PMID:21694771, PMID:22641616, PMID:22935518, PMID:29453283 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
increases activity
decreases response to substance
ISO
EXP
ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 mRNA]; ATF4 mutant form inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; NUPR1 mutant form promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Thapsigargin promotes the reaction [ATF4 protein binds to PMAIP1 promoter]
4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; salubrinal promotes the reaction [Thapsigargin results in increased expression of ATF4 protein]
Thapsigargin results in increased expression of ATF4 mRNA; Thapsigargin results in increased expression of ATF4 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]
Thapsigargin results in increased activity of ATF4 protein
ATF4 results in decreased susceptibility to Thapsigargin
CTD PMID:16298333, PMID:17283163, PMID:20022965, PMID:20589738, PMID:22378314, PMID:23383089, PMID:24648495, PMID:24865413, PMID:27226639, PMID:27358234, PMID:27587023, PMID:28223344, PMID:28844859, PMID:29109149, PMID:32578922 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Thapsigargin results in increased expression of ATF5 mRNA
Thapsigargin results in increased expression of ATF5 mRNA; Thapsigargin results in increased expression of ATF5 protein
CTD PMID:22378314, PMID:24648495, PMID:28942281 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases cleavage
increases expression
increases activity
ISO
EXP
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased cleavage of ATF6 protein]
Thapsigargin results in increased expression of ATF6 mRNA; Thapsigargin results in increased expression of ATF6 protein
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; ATF6 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of ATF6 protein]; Thapsigargin results in increased cleavage of and affects the localization of ATF6 protein
Thapsigargin results in increased activity of ATF6 protein
CTD PMID:17963750, PMID:18477628, PMID:20493918, PMID:22378314, PMID:23383089, PMID:23576437, PMID:24638036, PMID:26264395, PMID:27358234, PMID:27587023, PMID:28223344, PMID:30796460 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atg10 autophagy related 10 decreases expression ISO Thapsigargin results in decreased expression of ATG10 protein CTD PMID:24648495 NCBI chr 2:19,853,546...20,152,918
Ensembl chr 2:19,853,546...20,152,884
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects response to substance
increases expression
decreases activity
multiple interactions
ISO
EXP
ATP2A2 protein affects the susceptibility to Thapsigargin
Thapsigargin results in increased expression of ATP2A2 mRNA
Thapsigargin results in decreased activity of ATP2A2 protein
[Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium; Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA]; Thapsigargin results in increased expression of and results in decreased activity of ATP2A2 protein
CTD PMID:17287366, PMID:17475205, PMID:19244478, PMID:20816668 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Thapsigargin co-treated with Ionomycin] promotes the reaction [STIM1 protein binds to ATP2A3 protein] CTD PMID:18439569 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression ISO Thapsigargin results in increased expression of ATP5F1A mRNA CTD PMID:22378314 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 decreases expression ISO Thapsigargin results in decreased expression of ATP5MC1 mRNA CTD PMID:22378314 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Thapsigargin results in decreased expression of ATP5MC3 mRNA CTD PMID:22378314 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Thapsigargin results in decreased expression of ATP5MF mRNA CTD PMID:22378314 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression ISO Thapsigargin results in increased expression of ATP6V0A1 mRNA CTD PMID:29453283 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 increases expression ISO Thapsigargin results in increased expression of ATP6V0A2 mRNA CTD PMID:29453283 NCBI chr12:37,368,321...37,398,233
Ensembl chr12:37,363,906...37,425,596
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions
decreases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ATP6V0D2 mRNA] CTD PMID:19442820 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 increases expression ISO Thapsigargin results in increased expression of ATP8A1 protein CTD PMID:24648495 NCBI chr14:41,972,398...42,210,555
Ensembl chr14:42,015,347...42,206,311
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Thapsigargin results in increased expression of ATRX protein CTD PMID:24648495 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase increases expression ISO Thapsigargin results in increased expression of AUH mRNA CTD PMID:22378314 NCBI chr17:12,310,178...12,405,224
Ensembl chr17:12,310,214...12,405,205
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Thapsigargin results in decreased expression of AURKB mRNA CTD PMID:22378314 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Aven apoptosis and caspase activation inhibitor increases expression ISO Thapsigargin results in increased expression of AVEN mRNA CTD PMID:29453283 NCBI chr 3:103,980,612...104,117,193
Ensembl chr 3:104,042,168...104,117,192
JBrowse link
G B4galt5 beta-1,4-galactosyltransferase 5 increases expression ISO Thapsigargin results in increased expression of B4GALT5 mRNA CTD PMID:29453283 NCBI chr 3:164,039,731...164,055,561
Ensembl chr 3:164,039,731...164,095,878
JBrowse link
G Bach2 BTB domain and CNC homolog 2 increases expression ISO Thapsigargin results in increased expression of BACH2 mRNA CTD PMID:24247028 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Thapsigargin results in increased expression of BAD mRNA CTD PMID:22378314 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Banf1 BAF nuclear assembly factor 1 decreases expression ISO Thapsigargin results in decreased expression of BANF1 mRNA CTD PMID:22378314 NCBI chr 1:220,744,195...220,746,224
Ensembl chr 1:220,744,195...220,746,224
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO Thapsigargin results in decreased expression of BASP1 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases activity
multiple interactions
ISO Thapsigargin results in increased activity of BAX protein
Thapsigargin promotes the reaction [arsenite results in increased expression of BAX protein]
CTD PMID:20130848, PMID:26677073 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A increases expression ISO Thapsigargin results in increased expression of BAZ1A protein CTD PMID:24648495 NCBI chr 6:75,793,223...75,873,854
Ensembl chr 6:75,793,960...75,874,235
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B increases expression ISO Thapsigargin results in increased expression of BAZ1B protein CTD PMID:24648495 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Thapsigargin results in increased expression of BBC3 mRNA CTD PMID:16018998, PMID:22378314 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcas2 BCAS2, pre-mRNA processing factor decreases expression ISO Thapsigargin results in decreased expression of BCAS2 protein CTD PMID:24648495 NCBI chr 2:205,662,633...205,670,514
Ensembl chr 2:205,662,588...205,670,511
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO Thapsigargin results in increased expression of BCAT1 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bcat2 branched chain amino acid transaminase 2 increases expression ISO Thapsigargin results in increased expression of BCAT2 mRNA CTD PMID:22378314 NCBI chr 1:101,553,900...101,572,103
Ensembl chr 1:101,554,642...101,572,080
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression ISO Thapsigargin results in decreased expression of BCKDK mRNA
Thapsigargin results in decreased expression of BCKDK protein
CTD PMID:22378314, PMID:24648495 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
decreases phosphorylation
decreases expression
ISO Thapsigargin results in increased expression of BCL2 mRNA
Thapsigargin promotes the reaction [arsenite results in decreased expression of BCL2 protein]
Thapsigargin results in decreased phosphorylation of BCL2 protein
Thapsigargin results in decreased expression of BCL2 protein
CTD PMID:22378314, PMID:25611565, PMID:26677073 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
affects splicing
EXP
ISO
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; GW 4869 inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]; PLA2G6 mutant form inhibits the reaction [Thapsigargin affects the splicing of BCL2L1 mRNA]
BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of XBP1 protein alternative form]
Thapsigargin results in increased expression of BCL2L1 protein
CTD PMID:23885834, PMID:25762722 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 increases expression ISO Thapsigargin results in increased expression of BCLAF1 protein CTD PMID:24648495 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Begain brain-enriched guanylate kinase-associated decreases expression ISO Thapsigargin results in decreased expression of BEGAIN mRNA CTD PMID:22378314 NCBI chr 6:132,936,964...132,972,569
Ensembl chr 6:132,936,970...132,972,511
JBrowse link
G Bend6 BEN domain containing 6 increases expression ISO Thapsigargin results in increased expression of BEND6 mRNA CTD PMID:22378314 NCBI chr 9:38,297,253...38,351,312
Ensembl chr 9:38,297,322...38,351,024
JBrowse link
G Best1 bestrophin 1 increases expression ISO Thapsigargin results in increased expression of BEST1 mRNA CTD PMID:22378314 NCBI chr 1:226,033,146...226,049,893
Ensembl chr 1:226,030,875...226,049,929
JBrowse link
G Bet1 Bet1 golgi vesicular membrane trafficking protein decreases expression
multiple interactions
ISO Thapsigargin results in decreased expression of BET1 mRNA
[Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of BET1 mRNA
CTD PMID:19442820 NCBI chr 4:29,082,368...29,092,638
Ensembl chr 4:29,082,365...29,092,753
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like increases expression ISO Thapsigargin results in increased expression of BET1L mRNA CTD PMID:22378314 NCBI chr 1:213,602,836...213,606,507
Ensembl chr 1:213,602,850...213,605,643
JBrowse link
G Bex2 brain expressed X-linked 2 increases expression ISO Thapsigargin results in increased expression of BEX2 mRNA CTD PMID:29453283 NCBI chr  X:106,556,838...106,558,366
Ensembl chr  X:106,556,838...106,558,366
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression ISO Thapsigargin results in decreased expression of BHLHE40 mRNA CTD PMID:22378314 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO Thapsigargin results in decreased expression of BID mRNA CTD PMID:22378314 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Thapsigargin results in decreased expression of BIRC2 protein CTD PMID:16382148 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of BIRC3 protein]
Thapsigargin results in increased expression of BIRC3 mRNA; Thapsigargin results in increased expression of BIRC3 protein
CTD PMID:15339911 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Blm BLM RecQ like helicase increases expression ISO Thapsigargin results in increased expression of BLM protein CTD PMID:24648495 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Blnk B-cell linker decreases expression ISO Thapsigargin results in decreased expression of BLNK protein CTD PMID:24648495 NCBI chr 1:260,187,023...260,254,490
Ensembl chr 1:260,186,967...260,254,600
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 increases expression ISO Thapsigargin results in increased expression of BLOC1S2 mRNA CTD PMID:22378314 NCBI chr 1:263,913,901...263,920,989
Ensembl chr 1:263,913,854...263,920,962
JBrowse link
G Bmp2k BMP-2 inducible kinase decreases expression ISO Thapsigargin results in decreased expression of BMP2K protein CTD PMID:24648495 NCBI chr14:14,126,086...14,226,823
Ensembl chr14:14,129,725...14,192,048
JBrowse link
G Bms1 BMS1 ribosome biogenesis factor increases expression ISO Thapsigargin results in increased expression of BMS1 protein CTD PMID:24648495 NCBI chr 4:150,433,567...150,471,783
Ensembl chr 4:150,433,570...150,471,834
JBrowse link
G Bnc2 basonuclin 2 decreases expression ISO Thapsigargin results in decreased expression of BNC2 mRNA CTD PMID:22378314 NCBI chr 5:102,407,508...102,807,389
Ensembl chr 5:102,415,847...102,786,331
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Thapsigargin results in decreased expression of BNIP3 mRNA
Thapsigargin results in decreased expression of BNIP3 protein
CTD PMID:22378314, PMID:24648495 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bola3 bolA family member 3 decreases expression ISO Thapsigargin results in decreased expression of BOLA3 mRNA CTD PMID:22378314 NCBI chr 4:115,046,693...115,056,140
Ensembl chr 4:115,046,693...115,056,140
JBrowse link
G Bphl biphenyl hydrolase like decreases expression ISO Thapsigargin results in decreased expression of BPHL mRNA CTD PMID:22378314 NCBI chr17:31,498,877...31,535,172
Ensembl chr17:31,498,883...31,535,172
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
multiple interactions
affects localization
ISO Thapsigargin results in increased expression of BRCA1 mRNA; Thapsigargin results in increased expression of BRCA1 protein
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]
CTD PMID:16434996, PMID:29576526 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO Thapsigargin results in increased expression of BRCA2 mRNA; Thapsigargin results in increased expression of BRCA2 protein CTD PMID:16434996 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Brinp1 BMP/retinoic acid inducible neural specific 1 decreases expression ISO Thapsigargin results in decreased expression of BRINP1 mRNA CTD PMID:22378314 NCBI chr 5:84,919,416...85,123,828
Ensembl chr 5:84,919,367...85,123,829
JBrowse link
G Brsk1 BR serine/threonine kinase 1 increases expression ISO Thapsigargin results in increased expression of BRSK1 mRNA CTD PMID:29453283 NCBI chr 1:72,701,281...72,727,061
Ensembl chr 1:72,701,610...72,727,112
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Thapsigargin results in decreased expression of BUB1B mRNA CTD PMID:22378314 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qbp complement C1q binding protein decreases expression ISO Thapsigargin results in decreased expression of C1QBP mRNA CTD PMID:22378314 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C5 complement C5 increases expression ISO Thapsigargin results in increased expression of C5 mRNA CTD PMID:22378314 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca5b carbonic anhydrase 5B increases expression ISO Thapsigargin results in increased expression of CA5B mRNA CTD PMID:22378314 NCBI chr  X:32,232,106...32,291,124
Ensembl chr  X:32,232,142...32,292,072
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases expression ISO Thapsigargin results in increased expression of CACNA1A mRNA CTD PMID:19442820 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 decreases expression ISO Thapsigargin results in decreased expression of CACNA2D1 protein CTD PMID:24648495 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 decreases expression ISO Thapsigargin results in decreased expression of CACNA2D2 mRNA CTD PMID:22378314 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 decreases expression ISO Thapsigargin results in decreased expression of CACNG4 mRNA CTD PMID:22378314 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cadm1 cell adhesion molecule 1 decreases expression ISO Thapsigargin results in decreased expression of CADM1 mRNA CTD PMID:29453283 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions ISO Thapsigargin promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA] CTD PMID:20682585 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calcb calcitonin-related polypeptide, beta increases expression ISO Thapsigargin results in increased expression of CALCB mRNA CTD PMID:29453283 NCBI chr 1:184,271,116...184,276,480
Ensembl chr 1:184,271,590...184,276,475
JBrowse link
G Calr calreticulin increases expression ISO Thapsigargin results in increased expression of CALR mRNA; Thapsigargin results in increased expression of CALR protein CTD PMID:17353921, PMID:22378314, PMID:27587023, PMID:29453283 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin decreases expression
increases expression
ISO Thapsigargin results in decreased expression of CALU mRNA; Thapsigargin results in decreased expression of CALU protein
Thapsigargin results in increased expression of CALU mRNA
CTD PMID:21692457, PMID:22378314 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV multiple interactions EXP Thapsigargin inhibits the reaction [LIF protein results in increased activity of CAMK4 protein] CTD PMID:11073891 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Canx calnexin increases expression
affects localization
ISO
EXP
Thapsigargin results in increased expression of CANX mRNA; Thapsigargin results in increased expression of CANX protein
Thapsigargin affects the localization of CANX protein
CTD PMID:17353921, PMID:22378314, PMID:28315715, PMID:28940366, PMID:29453283 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Capn1 calpain 1 increases expression
multiple interactions
EXP Thapsigargin results in increased expression of CAPN1 protein
Thapsigargin promotes the reaction [cadmium acetate results in increased expression of CAPN1 protein]
CTD PMID:28347754 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Car10 carbonic anhydrase 10 decreases expression ISO Thapsigargin results in decreased expression of CA10 mRNA CTD PMID:22378314 NCBI chr10:80,790,151...81,297,621
Ensembl chr10:80,790,168...81,296,363
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO Thapsigargin results in increased expression of CARD9 mRNA CTD PMID:22378314 NCBI chr 3:3,798,346...3,806,841
Ensembl chr 3:3,798,347...3,806,713
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO Thapsigargin results in decreased expression of CARHSP1 mRNA CTD PMID:22378314 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Casp1 caspase 1 increases expression ISO Thapsigargin results in increased expression of CASP1 mRNA CTD PMID:30796460 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 multiple interactions
increases expression
increases activity
increases cleavage
ISO
EXP
demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of CASP12 protein modified form]; resveratrol inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased cleavage of CASP12 protein]
Thapsigargin results in increased cleavage of CASP12 protein alternative form
Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP12 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of CASP12 protein modified form]
CTD PMID:12198651, PMID:16338971, PMID:18477628, PMID:20493918, PMID:24224909, PMID:26264395, PMID:27638049 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 multiple interactions
increases activity
ISO Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP2 protein] CTD PMID:16388830 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
increases activity
increases metabolic processing
ISO
EXP
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; Bortezomib promotes the reaction [Thapsigargin results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Tacrolimus inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP3 protein]
Thapsigargin results in increased cleavage of CASP3 protein
1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased expression of CASP3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased activity of CASP3 protein]; HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of CASP3 protein modified form]
Thapsigargin results in increased metabolism of CASP3 protein
Thapsigargin results in increased expression of CASP3 protein; Thapsigargin results in increased expression of CASP3 protein alternative form
CTD PMID:12198651, PMID:12871656, PMID:16338971, PMID:16357177, PMID:16382148, PMID:16388830, PMID:17559149, PMID:18178165, PMID:19028522, PMID:20022965, PMID:20130848, PMID:20493918, PMID:20886113, PMID:22800509, PMID:23576437, PMID:25341683, PMID:27638049 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions ISO Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP4 protein]; Thapsigargin results in increased cleavage of and results in increased activity of CASP4 protein CTD PMID:17559149, PMID:25341683 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
ISO Doxorubicin inhibits the reaction [Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein]; tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased activity of CASP7 protein]; Thapsigargin results in increased activity of and results in increased cleavage of CASP7 protein CTD PMID:12198651, PMID:16298333, PMID:17559149, PMID:19139269, PMID:20022965 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases activity ISO Thapsigargin results in increased activity of CASP8 protein CTD PMID:16018998 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO Diclofenac inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Melatonin inhibits the reaction [Thapsigargin results in increased activity of CASP9 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased activity of CASP9 protein] CTD PMID:16018998, PMID:16388830, PMID:20130848, PMID:25341683 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor multiple interactions EXP Thapsigargin inhibits the reaction [Spermine binds to and results in increased activity of CASR protein] CTD PMID:11071898 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Catsper2 cation channel, sperm associated 2 decreases expression ISO Thapsigargin results in decreased expression of CATSPER2 mRNA CTD PMID:19442820 NCBI chr 3:113,357,361...113,379,498
Ensembl chr 3:113,357,365...113,376,751
JBrowse link
G Cbln2 cerebellin 2 precursor decreases expression ISO Thapsigargin results in decreased expression of CBLN2 mRNA CTD PMID:22378314 NCBI chr18:83,775,568...83,783,841
Ensembl chr18:83,777,665...83,782,930
JBrowse link
G Ccdc171 coiled-coil domain containing 171 decreases expression ISO Thapsigargin results in decreased expression of CCDC171 mRNA CTD PMID:22378314 NCBI chr 5:101,639,355...102,017,300 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Thapsigargin results in increased expression of CCL2 mRNA
Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Thapsigargin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
Thapsigargin results in decreased expression of CCL2 mRNA
CTD PMID:8764118, PMID:18799549, PMID:18951912, PMID:20830808 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression EXP Thapsigargin results in increased expression of CCL3 mRNA; Thapsigargin results in increased expression of CCL3 protein CTD PMID:20830808 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Thapsigargin results in increased expression of CCN1 mRNA CTD PMID:29453283 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Thapsigargin results in decreased expression of CCNA2 mRNA CTD PMID:22378314 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Thapsigargin results in decreased expression of CCNB1 mRNA CTD PMID:22378314 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb1ip1 cyclin B1 interacting protein 1 increases expression ISO Thapsigargin results in increased expression of CCNB1IP1 mRNA CTD PMID:22378314 NCBI chr15:27,720,220...27,736,528
Ensembl chr15:27,720,223...27,733,785
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Thapsigargin results in decreased expression of CCND1 mRNA CTD PMID:17332266, PMID:22378314 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnf cyclin F decreases expression ISO Thapsigargin results in decreased expression of CCNF mRNA CTD PMID:22378314 NCBI chr10:13,594,687...13,619,935
Ensembl chr10:13,594,687...13,619,935
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Thapsigargin results in increased expression of CCNG2 mRNA CTD PMID:17332266 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Ccnq cyclin Q decreases expression ISO Thapsigargin results in decreased expression of CCNQ protein CTD PMID:24648495 NCBI chr10:66,019,519...66,020,682
Ensembl chr10:66,019,520...66,020,682
JBrowse link
G Ccpg1 cell cycle progression 1 increases expression ISO Thapsigargin results in increased expression of CCPG1 mRNA CTD PMID:22378314 NCBI chr 8:79,660,634...79,692,044
Ensembl chr 8:79,660,657...79,692,039
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO Thapsigargin results in increased expression of CD44 mRNA CTD PMID:29453283 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Thapsigargin results in increased expression of CD55 mRNA CTD PMID:24247028 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd69 Cd69 molecule increases expression ISO Thapsigargin results in increased expression of CD69 mRNA CTD PMID:24247028 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd70 Cd70 molecule increases expression ISO Thapsigargin results in increased expression of CD70 mRNA CTD PMID:29453283 NCBI chr 9:9,842,585...9,845,728
Ensembl chr 9:9,842,585...9,845,728
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions
increases expression
ISO [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with caffeic acid] results in increased expression of CDC20 mRNA; [Thapsigargin co-treated with Drugs, Chinese Herbal] results in increased expression of CDC20 mRNA
Thapsigargin results in increased expression of CDC20 mRNA
CTD PMID:19442820 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Thapsigargin results in decreased expression of CDC45 mRNA CTD PMID:22378314 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc5l cell division cycle 5-like increases expression ISO Thapsigargin results in increased expression of CDC5L protein CTD PMID:24648495 NCBI chr 9:17,949,764...17,988,514
Ensembl chr 9:17,949,764...17,988,509
JBrowse link
G Cdc7 cell division cycle 7 decreases expression ISO Thapsigargin results in decreased expression of CDC7 mRNA CTD PMID:22378314 NCBI chr14:3,826,658...3,846,891
Ensembl chr14:3,826,659...3,846,891
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO Thapsigargin results in increased expression of CDCA2 protein CTD PMID:24648495 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO Thapsigargin results in decreased expression of CDCA7 mRNA CTD PMID:22378314 NCBI chr 3:59,153,281...59,163,916
Ensembl chr 3:59,153,280...59,163,913
JBrowse link
G Cdca7l cell division cycle associated 7 like decreases expression ISO Thapsigargin results in decreased expression of CDCA7L mRNA CTD PMID:22378314 NCBI chr 6:145,739,570...145,785,607
Ensembl chr 6:145,740,035...145,785,606
JBrowse link
G Cdh15 cadherin 15 increases expression ISO Thapsigargin results in increased expression of CDH15 mRNA CTD PMID:22378314 NCBI chr19:55,669,661...55,689,986
Ensembl chr19:55,669,626...55,689,992
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase decreases expression ISO Thapsigargin results in decreased expression of CDIPT protein CTD PMID:24648495 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Thapsigargin results in decreased expression of CDK1 mRNA CTD PMID:22378314 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression
increases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CDK2 mRNA]
Thapsigargin results in decreased expression of CDK2 mRNA
CTD PMID:19442820, PMID:22378314 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 increases expression ISO Thapsigargin results in increased expression of CDK2AP2 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 1:219,345,638...219,347,709
Ensembl chr 1:219,345,918...219,347,728
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 increases expression ISO Thapsigargin results in increased expression of CDK5RAP2 protein CTD PMID:24648495 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 increases expression ISO Thapsigargin results in increased expression of CDK5RAP3 mRNA CTD PMID:29453283 NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832
JBrowse link
G Cdk7 cyclin-dependent kinase 7 decreases expression ISO Thapsigargin results in decreased expression of CDK7 protein CTD PMID:24648495 NCBI chr 2:30,710,642...30,735,522
Ensembl chr 2:30,710,643...30,735,514
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Thapsigargin results in increased expression of CDKN1A mRNA CTD PMID:29453283 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression ISO Thapsigargin results in increased expression of CDR2 mRNA CTD PMID:22378314 NCBI chr 1:190,889,698...190,914,606
Ensembl chr 1:190,889,701...190,914,610
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
multiple interactions
ISO Thapsigargin results in increased expression of CEBPB mRNA; Thapsigargin results in increased expression of CEBPB protein alternative form
Thapsigargin promotes the reaction [CEBPB protein binds to NR1I2 promoter]
CTD PMID:22378314, PMID:25616597, PMID:29453283 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon increases expression ISO Thapsigargin results in increased expression of CEBPE mRNA CTD PMID:29453283 NCBI chr15:33,356,119...33,357,517
Ensembl chr15:33,355,947...33,358,138
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma increases expression ISO Thapsigargin results in increased expression of CEBPG mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 1:91,286,956...91,297,459
Ensembl chr 1:91,287,917...91,296,656
JBrowse link
G Cenpa centromere protein A decreases expression ISO Thapsigargin results in decreased expression of CENPA mRNA CTD PMID:22378314 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cenpf centromere protein F increases expression ISO Thapsigargin results in increased expression of CENPF mRNA CTD PMID:19442820 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cenpu centromere protein U decreases expression ISO Thapsigargin results in decreased expression of CENPU mRNA CTD PMID:22378314 NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO Thapsigargin results in increased expression of CEP290 protein CTD PMID:24648495 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Ces5a carboxylesterase 5A decreases expression ISO Thapsigargin results in decreased expression of CES5A protein CTD PMID:24648495 NCBI chr19:12,097,529...12,136,579
Ensembl chr19:12,097,632...12,136,240
JBrowse link
G Cetn2 centrin 2 decreases expression ISO Thapsigargin results in decreased expression of CETN2 protein CTD PMID:24648495 NCBI chr  X:152,927,852...152,933,095
Ensembl chr  X:152,927,718...152,932,953
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]; Thapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; Thapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] CTD PMID:18230692 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression ISO Thapsigargin results in increased expression of CGA mRNA CTD PMID:21694771, PMID:29453283 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Cgn cingulin decreases expression ISO Thapsigargin results in decreased expression of CGN mRNA CTD PMID:29453283 NCBI chr 2:195,909,691...195,937,130
Ensembl chr 2:195,909,626...195,935,878
JBrowse link
G Cgnl1 cingulin-like 1 increases expression
decreases expression
ISO Thapsigargin results in increased expression of CGNL1 protein
Thapsigargin results in decreased expression of CGNL1 mRNA
CTD PMID:24648495, PMID:29453283 NCBI chr 8:78,126,670...78,278,490
Ensembl chr 8:78,126,675...78,233,430
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Thapsigargin results in decreased expression of CHAC1 mRNA CTD PMID:19442820 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A increases expression
decreases expression
ISO Thapsigargin results in increased expression of CHAF1A mRNA
Thapsigargin results in decreased expression of CHAF1A mRNA
CTD PMID:19442820, PMID:22378314 NCBI chr 9:11,000,869...11,027,631
Ensembl chr 9:11,001,129...11,027,506
JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B decreases expression ISO Thapsigargin results in decreased expression of CHAF1B mRNA CTD PMID:22378314 NCBI chr11:34,101,248...34,121,371
Ensembl chr11:34,101,197...34,121,378
JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 decreases expression ISO Thapsigargin results in decreased expression of CHCHD6 protein CTD PMID:24648495 NCBI chr 4:121,340,952...121,565,222
Ensembl chr 4:121,340,952...121,565,212
JBrowse link
G Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 decreases expression ISO Thapsigargin results in decreased expression of CHCHD7 protein CTD PMID:24648495 NCBI chr 5:16,843,253...16,847,809
Ensembl chr 5:16,845,631...16,847,776
JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 increases expression ISO Thapsigargin results in increased expression of CHD4 protein CTD PMID:24648495 NCBI chr 4:157,612,531...157,645,660
Ensembl chr 4:157,612,536...157,645,659
JBrowse link
G Chek1 checkpoint kinase 1 decreases expression ISO Thapsigargin results in decreased expression of CHEK1 mRNA CTD PMID:22378314 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chga chromogranin A decreases expression
increases expression
ISO Thapsigargin results in decreased expression of CHGA mRNA
Thapsigargin results in increased expression of CHGA mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568
JBrowse link
G Chid1 chitinase domain containing 1 decreases expression ISO Thapsigargin results in decreased expression of CHID1 protein CTD PMID:24648495 NCBI chr 1:214,476,418...214,511,569
Ensembl chr 1:214,476,387...214,511,529
JBrowse link
G Chpf chondroitin polymerizing factor increases expression ISO Thapsigargin results in increased expression of CHPF mRNA CTD PMID:22378314 NCBI chr 9:82,669,199...82,673,898
Ensembl chr 9:82,669,204...82,673,898
JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression ISO Thapsigargin results in increased expression of CHPT1 mRNA CTD PMID:22378314 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium] CTD PMID:18316702 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit decreases expression ISO Thapsigargin results in decreased expression of CHRNA3 mRNA CTD PMID:22378314 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit decreases expression ISO Thapsigargin results in decreased expression of CHRNA5 mRNA CTD PMID:22378314 NCBI chr 8:59,561,817...59,590,172
Ensembl chr 8:59,561,721...59,590,172
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Thapsigargin results in decreased expression of CHRNB4 mRNA CTD PMID:22378314 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Chst15 carbohydrate sulfotransferase 15 increases expression ISO Thapsigargin results in increased expression of CHST15 mRNA CTD PMID:22378314 NCBI chr 1:204,243,396...204,328,960
Ensembl chr 1:204,245,645...204,322,544
JBrowse link
G Cirbp cold inducible RNA binding protein increases expression ISO Thapsigargin results in increased expression of CIRBP mRNA CTD PMID:29453283 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO Thapsigargin results in increased expression of CKAP5 protein CTD PMID:24648495 NCBI chr 3:80,424,320...80,526,583
Ensembl chr 3:80,468,154...80,526,593
JBrowse link
G Ckb creatine kinase B decreases expression ISO Thapsigargin results in decreased expression of CKB mRNA; Thapsigargin results in decreased expression of CKB protein CTD PMID:21692457, PMID:22378314 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clcc1 chloride channel CLIC-like 1 increases expression ISO Thapsigargin results in increased expression of CLCC1 mRNA CTD PMID:22378314 NCBI chr 2:211,450,426...211,479,885
Ensembl chr 2:211,450,484...211,479,884
JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO Thapsigargin results in increased expression of CLEC11A mRNA CTD PMID:19442820 NCBI chr 1:100,290,374...100,293,515
Ensembl chr 1:100,289,295...100,293,558
JBrowse link
G Cln8 CLN8, transmembrane ER and ERGIC protein decreases expression ISO Thapsigargin results in decreased expression of CLN8 protein CTD PMID:24648495 NCBI chr16:79,828,321...79,838,212
Ensembl chr16:79,828,324...79,838,212
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression ISO Thapsigargin results in increased expression of CLPP mRNA CTD PMID:22378314 NCBI chr 9:10,048,715...10,056,068
Ensembl chr 9:10,048,886...10,054,359
JBrowse link
G Cltc clathrin heavy chain increases expression ISO Thapsigargin results in increased expression of CLTC protein CTD PMID:24648495 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Cnn3 calponin 3 decreases expression ISO Thapsigargin results in decreased expression of CNN3 mRNA CTD PMID:22378314 NCBI chr 2:225,005,069...225,036,179
Ensembl chr 2:225,005,019...225,036,188
JBrowse link
G Cntnap2 contactin associated protein 2 increases expression ISO Thapsigargin results in increased expression of CNTNAP2 mRNA CTD PMID:22378314 NCBI chr 4:74,700,539...77,025,463 JBrowse link
G Cog1 component of oligomeric golgi complex 1 increases expression ISO Thapsigargin results in increased expression of COG1 mRNA CTD PMID:22378314 NCBI chr10:102,167,594...102,180,569
Ensembl chr10:102,167,771...102,180,569
JBrowse link
G Cog3 component of oligomeric golgi complex 3 increases expression ISO Thapsigargin results in increased expression of COG3 mRNA CTD PMID:22378314 NCBI chr15:57,753,814...57,805,627
Ensembl chr15:57,755,189...57,805,184
JBrowse link
G Cog6 component of oligomeric golgi complex 6 increases expression ISO Thapsigargin results in increased expression of COG6 mRNA CTD PMID:22378314 NCBI chr 2:142,197,566...142,235,054
Ensembl chr 2:142,196,754...142,235,066
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Thapsigargin results in increased expression of COL11A1 protein CTD PMID:24648495 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression
decreases expression
ISO Thapsigargin results in increased expression of COL5A1 mRNA
Thapsigargin results in decreased expression of COL5A1 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Thapsigargin results in increased expression of COL5A2 protein CTD PMID:24648495 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col6a3 collagen type VI alpha 3 chain multiple interactions ISO Thapsigargin promotes the reaction [COL6A3 gene mutant form results in increased susceptibility to Rotenone] CTD PMID:18435905 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Colec12 collectin sub-family member 12 decreases expression ISO Thapsigargin results in decreased expression of COLEC12 protein CTD PMID:24648495 NCBI chr18:867,048...1,054,047
Ensembl chr18:867,048...1,052,606
JBrowse link
G Copa COPI coat complex subunit alpha increases expression ISO Thapsigargin results in increased expression of COPA mRNA CTD PMID:22378314 NCBI chr13:90,467,285...90,508,894
Ensembl chr13:90,467,265...90,508,932
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 increases expression ISO Thapsigargin results in increased expression of COPG1 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 4:119,815,041...119,840,997
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Thapsigargin results in decreased expression of COPS4 protein CTD PMID:21692457 NCBI chr14:10,718,863...10,749,134
Ensembl chr14:10,718,844...10,749,120
JBrowse link
G Cops7a COP9 signalosome subunit 7A decreases expression ISO Thapsigargin results in decreased expression of COPS7A protein CTD PMID:24648495 NCBI chr 4:157,479,549...157,486,944
Ensembl chr 4:157,479,549...157,486,914
JBrowse link
G Coq3 coenzyme Q3 methyltransferase decreases expression ISO Thapsigargin results in decreased expression of COQ3 mRNA CTD PMID:22378314 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Coq8a coenzyme Q8A increases expression ISO Thapsigargin results in increased expression of COQ8A mRNA CTD PMID:22378314 NCBI chr13:98,451,629...98,480,438
Ensembl chr13:98,451,637...98,480,419
JBrowse link
G Coro1a coronin 1A decreases expression ISO Thapsigargin results in decreased expression of CORO1A mRNA CTD PMID:22378314 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO Thapsigargin results in decreased expression of COTL1 protein CTD PMID:24648495 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cox10 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 increases expression ISO Thapsigargin results in increased expression of COX10 mRNA CTD PMID:22378314 NCBI chr10:50,439,778...50,563,920
Ensembl chr10:50,439,782...50,574,539
JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 increases expression ISO Thapsigargin results in increased expression of COX11 mRNA CTD PMID:22378314 NCBI chr10:78,168,691...78,173,845
NCBI chr10:78,102,620...78,174,584
Ensembl chr10:78,111,050...78,174,584
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 decreases expression ISO Thapsigargin results in decreased expression of COX17 mRNA CTD PMID:22378314 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 decreases expression ISO Thapsigargin results in decreased expression of COX6B1 mRNA CTD PMID:22378314 NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859
Ensembl chr 2:89,075,975...89,084,859
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Thapsigargin results in decreased expression of COX6C mRNA CTD PMID:22378314 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO Thapsigargin results in decreased expression of COX7B mRNA CTD PMID:22378314 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676
JBrowse link
G Cpne1 copine 1 decreases expression ISO Thapsigargin results in decreased expression of CPNE1 protein CTD PMID:21692457 NCBI chr 3:151,617,733...151,625,448
NCBI chr 3:152,150,143...152,192,936
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Cpsf1 cleavage and polyadenylation specific factor 1 increases expression ISO Thapsigargin results in increased expression of CPSF1 protein CTD PMID:24648495 NCBI chr 7:117,661,779...117,672,373
Ensembl chr 7:117,661,661...117,672,373
JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c increases expression ISO Thapsigargin results in increased expression of CPT1C mRNA CTD PMID:22378314 NCBI chr 1:100,955,094...100,970,579
Ensembl chr 1:100,955,095...100,969,560
JBrowse link
G Crabp1 cellular retinoic acid binding protein 1 decreases expression ISO Thapsigargin results in decreased expression of CRABP1 mRNA CTD PMID:22378314 NCBI chr 8:59,344,097...59,352,135
Ensembl chr 8:59,344,083...59,352,132
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 decreases expression ISO Thapsigargin results in decreased expression of CRABP2 mRNA CTD PMID:22378314 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Crat carnitine O-acetyltransferase increases expression ISO Thapsigargin results in increased expression of CRAT mRNA CTD PMID:22378314 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects localization
multiple interactions
ISO Thapsigargin affects the localization of CREB1 mRNA
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA]; Emetine inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA]
CTD PMID:29576526 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 increases activity
multiple interactions
ISO Thapsigargin results in increased activity of CREB3L1 protein
[Thapsigargin results in increased activity of CREB3L1 protein] which results in increased expression of VEGFA mRNA
CTD PMID:23383089 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 increases expression ISO Thapsigargin results in increased expression of CREB3L2 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 4:64,869,285...64,981,519
Ensembl chr 4:64,869,026...64,981,384
JBrowse link
G Crebbp CREB binding protein increases expression ISO Thapsigargin results in increased expression of CREBBP mRNA CTD PMID:24247028 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 decreases expression ISO Thapsigargin results in decreased expression of CREG1 protein CTD PMID:24648495 NCBI chr13:83,972,186...83,984,675
Ensembl chr13:83,972,212...83,984,675
JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 increases expression ISO Thapsigargin results in increased expression of CRELD1 mRNA CTD PMID:22378314 NCBI chr 4:145,440,284...145,449,894
Ensembl chr 4:145,440,114...145,449,892
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 increases expression
decreases expression
ISO Thapsigargin results in increased expression of CRELD2 mRNA; Thapsigargin results in increased expression of CRELD2 protein
Thapsigargin results in decreased expression of CRELD2 protein
CTD PMID:22378314, PMID:24648495, PMID:29453283 NCBI chr 7:129,812,746...129,819,641
Ensembl chr 7:129,812,789...129,819,634
JBrowse link
G Crk CRK proto-oncogene, adaptor protein multiple interactions EXP Thapsigargin inhibits the reaction [Sincalide results in increased phosphorylation of CRK protein] CTD PMID:16187300 NCBI chr10:63,829,731...63,855,999
Ensembl chr10:63,829,807...63,852,780
JBrowse link
G Crtac1 cartilage acidic protein 1 increases expression ISO Thapsigargin results in increased expression of CRTAC1 mRNA CTD PMID:29453283 NCBI chr 1:261,527,009...261,669,614
Ensembl chr 1:261,514,141...261,669,586
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Thapsigargin results in decreased expression of CRY1 mRNA CTD PMID:22378314 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Crybb2 crystallin, beta B2 increases expression ISO Thapsigargin results in increased expression of CRYBB2 mRNA CTD PMID:29453283 NCBI chr12:49,577,580...49,588,555
Ensembl chr12:49,578,633...49,588,555
JBrowse link
G Crybg3 crystallin beta-gamma domain containing 3 increases expression ISO Thapsigargin results in increased expression of CRYBG3 protein CTD PMID:24648495 NCBI chr11:42,895,610...43,006,568
Ensembl chr11:42,945,084...43,005,097
JBrowse link
G Cryz crystallin zeta multiple interactions
decreases expression
increases expression
ISO Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of CRYZ mRNA]
Thapsigargin results in decreased expression of CRYZ mRNA
CTD PMID:19442820, PMID:22378314 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Cs citrate synthase decreases expression ISO Thapsigargin results in decreased expression of CS mRNA CTD PMID:28223344 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 increases expression ISO Thapsigargin results in increased expression of CSNK2A2 mRNA CTD PMID:22378314 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 decreases expression ISO Thapsigargin results in decreased expression of CSPG5 mRNA CTD PMID:22378314 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Thapsigargin results in increased expression of CSRNP1 mRNA CTD PMID:29453283 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Thapsigargin results in decreased expression of CSRP2 mRNA CTD PMID:22378314 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 decreases expression ISO Thapsigargin results in decreased expression of CSTF2 mRNA CTD PMID:22378314 NCBI chr  X:104,882,726...104,909,746
Ensembl chr  X:104,882,704...104,909,739
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions ISO [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in decreased expression of CTF1 mRNA; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CTF1 mRNA] CTD PMID:19442820 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Thapsigargin results in increased expression of CTH mRNA; Thapsigargin results in increased expression of CTH protein CTD PMID:29453283 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctps1 CTP synthase 1 decreases expression ISO Thapsigargin results in decreased expression of CTPS mRNA CTD PMID:22378314 NCBI chr 5:139,475,934...139,505,065
Ensembl chr 5:139,475,934...139,505,065
JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component increases expression ISO Thapsigargin results in increased expression of CTR9 protein CTD PMID:24648495 NCBI chr 1:175,839,140...175,869,167
Ensembl chr 1:175,839,108...175,869,165
JBrowse link
G Ctsl cathepsin L multiple interactions ISO Thapsigargin inhibits the reaction [Cadmium Chloride results in increased cleavage of CTSL protein] CTD PMID:25639782 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Ctxn1 cortexin 1 decreases expression ISO Thapsigargin results in decreased expression of CTXN1 mRNA CTD PMID:29453283 NCBI chr12:2,534,212...2,535,823
Ensembl chr12:2,534,212...2,535,822
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of CXCL2 mRNA] CTD PMID:19442820 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Thapsigargin results in increased expression of CXCL1 mRNA CTD PMID:8764118 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyb561d2 cytochrome b561 family, member D2 decreases expression ISO Thapsigargin results in decreased expression of CYB561D2 protein CTD PMID:24648495 NCBI chr 8:116,295,328...116,297,879
Ensembl chr 8:116,295,329...116,297,858
JBrowse link
G Cyb5a cytochrome b5 type A decreases expression ISO Thapsigargin results in decreased expression of CYB5A mRNA CTD PMID:22378314 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyb5b cytochrome b5 type B decreases expression ISO Thapsigargin results in decreased expression of CYB5B mRNA CTD PMID:22378314 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189
JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 increases expression ISO Thapsigargin results in increased expression of CYB5R1 mRNA CTD PMID:29453283 NCBI chr13:51,229,697...51,236,447
Ensembl chr13:51,229,890...51,236,463
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression ISO Thapsigargin results in decreased expression of CYBA mRNA CTD PMID:29453283 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cycs cytochrome c, somatic decreases expression ISO Thapsigargin results in decreased expression of CYCS mRNA CTD PMID:22378314 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyfip1 cytoplasmic FMR1 interacting protein 1 increases expression ISO Thapsigargin results in increased expression of CYFIP1 protein CTD PMID:24648495 NCBI chr 1:114,258,773...114,347,138
Ensembl chr 1:114,258,719...114,347,137
JBrowse link
G Cygb cytoglobin decreases expression ISO Thapsigargin results in decreased expression of CYGB mRNA CTD PMID:22378314 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO Thapsigargin results in increased expression of CYP1B1 mRNA CTD PMID:29453283 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO Thapsigargin results in decreased expression of CYP4F3 mRNA CTD PMID:19442820 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 increases expression ISO Thapsigargin results in increased expression of CYP4V2 mRNA CTD PMID:22378314 NCBI chr16:50,111,803...50,136,741
Ensembl chr16:50,111,306...50,136,727
JBrowse link
G Cyp4x1 cytochrome P450, family 4, subfamily x, polypeptide 1 increases expression ISO Thapsigargin results in increased expression of CYP4X1 mRNA CTD PMID:29453283 NCBI chr 5:133,929,532...133,959,447
Ensembl chr 5:133,929,532...133,959,447
JBrowse link
G Dap death-associated protein multiple interactions
increases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of DAP mRNA]
Thapsigargin results in increased expression of DAP mRNA
CTD PMID:19442820, PMID:22378314 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein decreases expression ISO Thapsigargin results in decreased expression of DBI mRNA CTD PMID:22378314 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dbnl drebrin-like decreases expression ISO Thapsigargin results in decreased expression of DBNL mRNA CTD PMID:22378314 NCBI chr14:86,029,335...86,044,364
Ensembl chr14:86,029,335...86,044,364
JBrowse link
G Dctpp1 dCTP pyrophosphatase 1 decreases expression ISO Thapsigargin results in decreased expression of DCTPP1 mRNA CTD PMID:22378314 NCBI chr 1:198,703,459...198,706,852
Ensembl chr 1:198,703,461...198,706,852
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 decreases expression ISO Thapsigargin results in decreased expression of DDAH1 mRNA CTD PMID:22378314 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 increases expression ISO Thapsigargin results in increased expression of DDB1 protein CTD PMID:24648495 NCBI chr 1:226,657,561...226,683,356
Ensembl chr 1:226,657,561...226,683,347
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Thapsigargin results in decreased expression of DDC mRNA CTD PMID:22378314 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO Thapsigargin results in decreased expression of DDIAS mRNA CTD PMID:22378314 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
increases activity
decreases response to substance
ISO
EXP
ATF6 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; Thapsigargin promotes the reaction [DDIT3 protein binds to LCN2 promoter]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein
Thapsigargin results in increased expression of DDIT3 mRNA; Thapsigargin results in increased expression of DDIT3 protein
1-Deoxynojirimycin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; GW 506033X inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; salubrinal promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin results in increased expression of and affects the localization of DDIT3 protein
Thapsigargin results in increased activity of DDIT3 protein
2-aminoethoxydiphenyl borate inhibits the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Glutathione inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased expression of DDIT3 protein]]; Thapsigargin promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]
DDIT3 results in decreased susceptibility to Thapsigargin
CTD PMID:16298333, PMID:16330322, PMID:16338971, PMID:17283163, PMID:17332266, PMID:17353921, PMID:17475668, PMID:19028522, PMID:19135031, PMID:19139269, PMID:19285962, PMID:19428936, PMID:20022965, PMID:20493918, PMID:20589738, PMID:20626587, PMID:21525004, PMID:21694771, PMID:22378314, PMID:22509299, PMID:22641616, PMID:22800509, PMID:22843330, PMID:22935518, PMID:24648495, PMID:24668805, PMID:24865413, PMID:25289770, PMID:25324550, PMID:25341683, PMID:25611565, PMID:26264395, PMID:27226639, PMID:27358234, PMID:27587023, PMID:27638049, PMID:28223344, PMID:28315715, PMID:28844859, PMID:28940366, PMID:28942281, PMID:29109149, PMID:29414781, PMID:29453283, PMID:30508555, PMID:32574669, PMID:32578922 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit increases expression ISO Thapsigargin results in increased expression of DDOST mRNA CTD PMID:22378314 NCBI chr 5:156,668,924...156,676,036
Ensembl chr 5:156,668,712...156,676,035
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 increases expression ISO Thapsigargin results in increased expression of DDR2 protein CTD PMID:24648495 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddrgk1 DDRGK domain containing 1 increases expression ISO Thapsigargin results in increased expression of DDRGK1 mRNA CTD PMID:29453283 NCBI chr 3:123,195,580...123,206,828
Ensembl chr 3:123,195,580...123,206,828
JBrowse link
G Dennd4c DENN domain containing 4C increases expression ISO Thapsigargin results in increased expression of DENND4C protein CTD PMID:24648495 NCBI chr 5:105,100,081...105,195,634
Ensembl chr 5:105,114,433...105,193,988
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression ISO Thapsigargin results in decreased expression of DEPDC1B mRNA CTD PMID:22378314 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein increases expression ISO Thapsigargin results in increased expression of DEPTOR mRNA CTD PMID:22378314 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Derl2 derlin 2 increases expression ISO Thapsigargin results in increased expression of DERL2 mRNA CTD PMID:22378314 NCBI chr10:57,641,682...57,653,554
Ensembl chr10:57,644,207...57,653,359
JBrowse link
G Dglucy D-glutamate cyclase decreases expression ISO Thapsigargin results in decreased expression of DGLUCY mRNA CTD PMID:22378314 NCBI chr 6:124,786,164...124,870,244
Ensembl chr 6:124,786,097...124,872,277
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Thapsigargin results in decreased expression of DHCR24 mRNA CTD PMID:22378314 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Thapsigargin results in decreased expression of DHCR7 mRNA CTD PMID:22378314 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Dhrs13 dehydrogenase/reductase 13 increases expression ISO Thapsigargin results in increased expression of DHRS13 mRNA CTD PMID:29453283 NCBI chr10:65,329,407...65,334,533
Ensembl chr10:65,329,940...65,334,500
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Thapsigargin results in increased expression of DHRS3 mRNA CTD PMID:22378314 NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
JBrowse link
G Dhx36 DEAH-box helicase 36 increases expression ISO Thapsigargin results in increased expression of DHX36 protein CTD PMID:24648495 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dhx9 DExH-box helicase 9 increases expression ISO Thapsigargin results in increased expression of DHX9 protein CTD PMID:24648495 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein affects response to substance
increases expression
affects localization
ISO DIABLO protein affects the susceptibility to Thapsigargin
Thapsigargin results in increased expression of DIABLO mRNA
Thapsigargin affects the localization of DIABLO protein
CTD PMID:15339911, PMID:16382148, PMID:22378314 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Diaph2 diaphanous-related formin 2 increases expression ISO Thapsigargin results in increased expression of DIAP2 protein CTD PMID:24648495 NCBI chr  X:99,722,910...100,363,228 JBrowse link
G Diaph3 diaphanous-related formin 3 increases expression ISO Thapsigargin results in increased expression of DIAPH3 protein CTD PMID:24648495 NCBI chr15:69,928,507...70,400,077
Ensembl chr15:70,039,424...70,399,924
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Thapsigargin results in decreased expression of DKK1 mRNA CTD PMID:22378314 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Thapsigargin results in decreased expression of DLD mRNA CTD PMID:22378314 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Thapsigargin results in increased expression of DLG4 mRNA CTD PMID:22378314 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of DLGAP5 mRNA
Thapsigargin results in increased expression of DLGAP5 protein
CTD PMID:22378314, PMID:24648495 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Thapsigargin results in decreased expression of DLK1 mRNA CTD PMID:22378314 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dlx5 distal-less homeobox 5 decreases expression ISO Thapsigargin results in decreased expression of DLX5 mRNA CTD PMID:22378314 NCBI chr 4:32,387,741...32,392,085
Ensembl chr 4:32,387,741...32,392,007
JBrowse link
G Dmac2l distal membrane arm assembly complex 2 like decreases expression ISO Thapsigargin results in decreased expression of DMAC2L mRNA CTD PMID:22378314 NCBI chr 6:92,057,782...92,076,022
Ensembl chr 6:92,057,807...92,076,021
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Thapsigargin results in decreased expression of DNAJA1 mRNA CTD PMID:22378314 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression ISO Thapsigargin results in increased expression of DNAJA3 mRNA CTD PMID:22378314 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
increases expression
decreases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA]; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of DNAJB11 mRNA]
Thapsigargin results in increased expression of DNAJB11 mRNA; Thapsigargin results in increased expression of DNAJB11 protein
CTD PMID:19442820, PMID:22378314, PMID:26085089, PMID:29453283 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Thapsigargin results in increased expression of DNAJB9 mRNA CTD PMID:19135031, PMID:22378314, PMID:29453283 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 affects expression ISO Thapsigargin affects the expression of DNAJC1 mRNA CTD PMID:24247028 NCBI chr17:84,986,994...85,141,464
Ensembl chr17:84,986,991...85,141,210
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 increases expression ISO Thapsigargin results in increased expression of DNAJC10 mRNA; Thapsigargin results in increased expression of DNAJC10 protein CTD PMID:17353921, PMID:29453283 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression
multiple interactions
ISO Thapsigargin results in increased expression of DNAJC3 mRNA; Thapsigargin results in increased expression of DNAJC3 protein
[DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin
CTD PMID:19135031, PMID:26085089, PMID:29453283 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal increases expression ISO Thapsigargin results in increased expression of DNASE2 mRNA CTD PMID:22378314 NCBI chr19:26,022,855...26,025,523
Ensembl chr19:26,022,849...26,025,532
JBrowse link
G Dnhd1 dynein heavy chain domain 1 increases expression ISO Thapsigargin results in increased expression of DNHD1 mRNA CTD PMID:22378314 NCBI chr 1:170,473,792...170,570,220
Ensembl chr 1:170,471,272...170,565,063
JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Thapsigargin results in increased expression of DNM1L mRNA CTD PMID:28940366 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt1 DNA methyltransferase 1 increases expression ISO Thapsigargin results in increased expression of DNMT1 protein CTD PMID:24648495 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dock7 dedicator of cytokinesis 7 increases expression ISO Thapsigargin results in increased expression of DOCK7 protein CTD PMID:24648495 NCBI chr 5:117,595,194...117,780,844
Ensembl chr 5:117,596,136...117,780,777
JBrowse link
G Dpf1 double PHD fingers 1 decreases expression ISO Thapsigargin results in decreased expression of DPF1 mRNA CTD PMID:22378314 NCBI chr 1:87,248,448...87,258,070
Ensembl chr 1:87,248,489...87,258,070
JBrowse link
G Dph5 diphthamide biosynthesis 5 increases expression ISO Thapsigargin results in increased expression of DPH5 mRNA CTD PMID:22378314 NCBI chr 2:218,834,034...218,866,763
Ensembl chr 2:218,834,034...218,866,761
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO Thapsigargin results in decreased expression of DPYSL3 mRNA CTD PMID:22378314 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 multiple interactions
increases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of DPYSL4 mRNA] CTD PMID:19442820 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 decreases expression ISO Thapsigargin results in decreased expression of DSCC1 mRNA CTD PMID:22378314 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569
JBrowse link
G Dse dermatan sulfate epimerase decreases expression ISO Thapsigargin results in decreased expression of DSE protein CTD PMID:24648495 NCBI chr20:27,703,738...27,784,982
Ensembl chr20:27,703,732...27,782,586
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Thapsigargin results in decreased expression of DTL mRNA CTD PMID:22378314 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Dtna dystrobrevin, alpha decreases expression ISO Thapsigargin results in decreased expression of DTNA mRNA CTD PMID:22378314 NCBI chr18:14,544,725...14,671,514
Ensembl chr18:14,471,213...14,657,332
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Thapsigargin results in increased expression of DUSP1 mRNA CTD PMID:29453283 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp26 dual specificity phosphatase 26 increases expression ISO Thapsigargin results in increased expression of DUSP26 mRNA CTD PMID:22378314 NCBI chr16:64,798,782...64,806,459
Ensembl chr16:64,798,778...64,806,050
JBrowse link
G Dusp5 dual specificity phosphatase 5 decreases expression ISO Thapsigargin results in decreased expression of DUSP5 mRNA CTD PMID:29453283 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression
decreases expression
ISO Thapsigargin results in increased expression of DUSP6 mRNA
Thapsigargin results in decreased expression of DUSP6 mRNA
CTD PMID:22378314, PMID:24247028 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dut deoxyuridine triphosphatase decreases expression ISO Thapsigargin results in decreased expression of DUT mRNA
Thapsigargin results in decreased expression of DUT protein
CTD PMID:22378314, PMID:24648495 NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
JBrowse link
G Dym dymeclin decreases expression ISO Thapsigargin results in decreased expression of DYM protein CTD PMID:24648495 NCBI chr18:70,996,074...71,313,033
Ensembl chr18:70,996,044...71,313,084
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Thapsigargin results in decreased expression of DYNC1I1 mRNA CTD PMID:22378314 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Dync2i2 dynein 2 intermediate chain 2 decreases expression ISO Thapsigargin results in decreased expression of DYNC2I2 mRNA CTD PMID:22378314 NCBI chr 3:8,599,251...8,615,329
Ensembl chr 3:8,599,148...8,615,532
JBrowse link
G Dyrk4 dual specificity tyrosine phosphorylation regulated kinase 4 increases expression ISO Thapsigargin results in increased expression of DYRK4 mRNA CTD PMID:22378314 NCBI chr 4:159,426,447...159,467,973
Ensembl chr 4:159,427,340...159,467,955
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Thapsigargin results in decreased expression of E2F1 mRNA CTD PMID:22378314 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Thapsigargin results in decreased expression of E2F2 mRNA CTD PMID:22378314 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f7 E2F transcription factor 7 decreases expression ISO Thapsigargin results in decreased expression of E2F7 mRNA CTD PMID:22378314 NCBI chr 7:53,275,659...53,318,261
Ensembl chr 7:53,275,676...53,316,481
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial decreases expression ISO Thapsigargin results in decreased expression of EARS2 mRNA CTD PMID:29453283 NCBI chr 1:191,997,512...192,025,350
Ensembl chr 1:191,997,512...192,025,350
JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Thapsigargin results in decreased expression of EBF1 mRNA CTD PMID:22378314 NCBI chr10:23,654,849...24,051,627
Ensembl chr10:23,661,013...24,050,209
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO Thapsigargin results in increased expression of ECH1 mRNA CTD PMID:22378314 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Edc4 enhancer of mRNA decapping 4 increases expression ISO Thapsigargin results in increased expression of EDC4 protein CTD PMID:24648495 NCBI chr19:37,852,659...37,864,651
Ensembl chr19:37,852,659...37,866,355
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Thapsigargin results in increased expression of EDEM1 mRNA CTD PMID:22378314, PMID:27587023 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Eef1akmt1 EEF1A lysine methyltransferase 1 decreases expression ISO Thapsigargin results in decreased expression of EEF1AKMT1 protein CTD PMID:24648495 NCBI chr15:37,813,115...37,830,932
Ensembl chr15:37,813,115...37,831,031
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 decreases expression ISO Thapsigargin results in decreased expression of EEPD1 mRNA CTD PMID:22378314 NCBI chr 8:26,651,241...26,758,330
Ensembl chr 8:26,652,121...26,758,325
JBrowse link
G Efr3a EFR3 homolog A decreases expression ISO Thapsigargin results in decreased expression of EFR3A protein CTD PMID:24648495 NCBI chr 7:106,535,428...106,616,805
Ensembl chr 7:106,535,434...106,616,805
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Thapsigargin inhibits the reaction [EGF protein affects the localization of PRKCB protein] CTD PMID:17991733 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Thapsigargin results in increased expression of EGFR protein CTD PMID:24648495 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression
ISO Thapsigargin results in increased expression of EGR1 mRNA
Thapsigargin results in decreased expression of EGR1 mRNA
CTD PMID:8764118, PMID:21694771, PMID:22378314 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 decreases expression EXP Thapsigargin results in decreased expression of EGR2 mRNA CTD PMID:20830808 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression ISO Thapsigargin results in increased expression of EIF1 mRNA CTD PMID:22378314 NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases expression
increases phosphorylation
ISO
EXP
Doxorubicin promotes the reaction [Thapsigargin results in increased phosphorylation of EIF2A protein]
Thapsigargin results in increased expression of EIF2A mRNA
Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein]
CTD PMID:12606582, PMID:16298333, PMID:17283163, PMID:17353921, PMID:19285962, PMID:19428936, PMID:20589738, PMID:22378314 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 increases phosphorylation
multiple interactions
ISO Thapsigargin results in increased phosphorylation of EIF2AK2 protein
imoxin inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK2 protein]
CTD PMID:24150608 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases acetylation
increases phosphorylation
increases expression
increases response to substance
ISO
EXP
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]
Thapsigargin results in increased acetylation of EIF2AK3 protein
Thapsigargin results in increased expression of EIF2AK3 mRNA; Thapsigargin results in increased expression of EIF2AK3 protein; Thapsigargin results in increased expression of EIF2AK3 protein modified form
EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of EIF2AK3 protein; EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein]; Thapsigargin promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2AK3 protein
EIF2AK3 gene mutant form results in increased susceptibility to Thapsigargin
CTD PMID:16324875, PMID:17283163, PMID:17963750, PMID:20022965, PMID:22378314, PMID:22509299, PMID:23576437, PMID:24150608, PMID:24224909, PMID:24648495, PMID:24865413, PMID:24898257, PMID:25341683, PMID:26264395, PMID:27358234, PMID:29653943, PMID:30796460 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
decreases phosphorylation
increases expression
increases phosphorylation
decreases response to substance
ISO
EXP
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]
Thapsigargin results in decreased phosphorylation of EIF2S1 protein
Thapsigargin results in increased expression of EIF2S1 mRNA
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of DDIT3 protein]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A mRNA]; EIF2S1 protein modified form affects the reaction [Thapsigargin results in increased expression of PPP1R15A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in decreased expression of TIMM17A protein]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of EIF2S1 protein]]; Thapsigargin results in increased activity of and results in increased phosphorylation of EIF2S1 protein
Thapsigargin results in increased expression of EIF2S1 protein modified form
EIF2S1 protein mutant form results in decreased susceptibility to Thapsigargin
EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein]; salubrinal inhibits the reaction [Thapsigargin results in increased expression of EIF2S1 mRNA]
CTD PMID:16324875, PMID:17553788, PMID:19233273, PMID:20022965, PMID:22509299, PMID:23576437, PMID:23690448, PMID:24150608, PMID:24224909, PMID:24315374, PMID:24648495, PMID:27587023, PMID:28844859, PMID:29109149, PMID:29414781, PMID:30508555, PMID:32578922 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta affects expression
increases expression
ISO Thapsigargin affects the expression of EIF2S2 mRNA
Thapsigargin results in increased expression of EIF2S2 mRNA
CTD PMID:22378314, PMID:24247028 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression ISO Thapsigargin results in increased expression of EIF3A protein CTD PMID:24648495 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I decreases expression ISO Thapsigargin results in decreased expression of EIF3I protein CTD PMID:21692457 NCBI chr 5:147,796,580...147,803,853
Ensembl chr 5:147,796,662...147,803,851
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Thapsigargin results in decreased expression of EIF4E mRNA; Thapsigargin results in decreased expression of EIF4E protein CTD PMID:24648495 NCBI chr 2:243,819,616...243,853,987
Ensembl chr 2:243,820,661...243,852,631
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Thapsigargin results in increased expression of EIF4EBP1 mRNA; Thapsigargin results in increased expression of EIF4EBP1 protein CTD PMID:29453283 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A affects response to substance ISO EIF5A protein affects the susceptibility to Thapsigargin CTD PMID:20376341 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression ISO Thapsigargin results in increased expression of EIF5B protein CTD PMID:24648495 NCBI chr 9:44,658,724...44,713,518
Ensembl chr 9:44,681,494...44,713,199
JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO Thapsigargin results in increased expression of ELF1 mRNA CTD PMID:29453283 NCBI chr15:61,772,544...61,868,442
Ensembl chr15:61,826,711...61,868,343
JBrowse link
G Elf3 E74 like ETS transcription factor 3 decreases expression ISO Thapsigargin results in decreased expression of ELF3 mRNA CTD PMID:22378314 NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
JBrowse link
G Elmo2 engulfment and cell motility 2 multiple interactions ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of ELMO2 mRNA] CTD PMID:19442820 NCBI chr 3:161,812,474...161,850,006
Ensembl chr 3:161,812,474...162,003,588
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 decreases expression ISO Thapsigargin results in decreased expression of ELOVL2 mRNA CTD PMID:22378314 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Emc4 ER membrane protein complex subunit 4 decreases expression ISO Thapsigargin results in decreased expression of EMC4 protein CTD PMID:24648495 NCBI chr 3:103,852,139...103,857,172
Ensembl chr 3:103,852,139...103,857,158
JBrowse link
G Emilin2 elastin microfibril interfacer 2 increases expression ISO Thapsigargin results in increased expression of EMILIN2 mRNA CTD PMID:29453283 NCBI chr 9:119,594,049...119,653,675
Ensembl chr 9:119,594,629...119,653,255
JBrowse link
G Eml2 EMAP like 2 increases expression ISO Thapsigargin results in increased expression of EML2 mRNA CTD PMID:22378314 NCBI chr 1:80,087,684...80,118,784
Ensembl chr 1:80,087,684...80,119,012
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO Thapsigargin results in decreased expression of ENC1 mRNA CTD PMID:22378314 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Endog endonuclease G decreases expression ISO Thapsigargin results in decreased expression of ENDOG mRNA CTD PMID:22378314 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Enkd1 enkurin domain containing 1 increases expression ISO Thapsigargin results in increased expression of ENKD1 mRNA CTD PMID:22378314 NCBI chr19:37,670,624...37,675,101
Ensembl chr19:37,670,624...37,675,077
JBrowse link
G Eno2 enolase 2 increases expression ISO Thapsigargin results in increased expression of ENO2 mRNA CTD PMID:29453283 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Eno3 enolase 3 increases expression ISO Thapsigargin results in increased expression of ENO3 mRNA CTD PMID:22378314 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of ENPP2 mRNA
Thapsigargin results in increased expression of ENPP2 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 decreases expression ISO Thapsigargin results in decreased expression of ENTPD5 protein CTD PMID:24648495 NCBI chr 6:108,087,677...108,123,811
Ensembl chr 6:108,087,418...108,120,579
JBrowse link
G Ep400 E1A binding protein p400 increases expression ISO Thapsigargin results in increased expression of EP400 protein CTD PMID:24648495 NCBI chr12:51,948,650...52,055,274
Ensembl chr12:51,948,650...52,055,271
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO Thapsigargin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx4 epoxide hydrolase 4 increases expression ISO Thapsigargin results in increased expression of EPHX4 mRNA CTD PMID:29453283 NCBI chr14:3,360,680...3,389,996
Ensembl chr14:3,360,712...3,389,943
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase increases expression ISO Thapsigargin results in increased expression of EPRS1 mRNA
Thapsigargin results in increased expression of EPRS protein
CTD PMID:22378314, PMID:24648495 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO Thapsigargin results in decreased expression of ERCC6L mRNA CTD PMID:22378314 NCBI chr  X:72,018,373...72,034,140
Ensembl chr  X:72,018,373...72,034,099
JBrowse link
G Erf Ets2 repressor factor multiple interactions
increases expression
ISO caffeic acid promotes the reaction [Thapsigargin results in increased expression of ERF mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of ERF mRNA] CTD PMID:19442820 NCBI chr 1:82,112,449...82,120,902
Ensembl chr 1:82,112,449...82,120,902
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
affects splicing
increases expression
increases phosphorylation
ISO
EXP
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; [Thapsigargin co-treated with HRAS protein] results in increased expression of ERN1 protein; Apigenin inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; Thapsigargin inhibits the reaction [7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein]]
Thapsigargin affects the splicing of ERN1 mRNA
Thapsigargin results in increased expression of ERN1 protein
Thapsigargin results in increased expression of ERN1 mRNA; Thapsigargin results in increased expression of ERN1 protein; Thapsigargin results in increased expression of ERN1 protein modified form
1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; [Thapsigargin affects the splicing of ERN1 mRNA] which results in increased expression of ERN1 protein alternative form; BCL2L1 protein inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of ERN1 protein]; EUK-134 inhibits the reaction [Thapsigargin results in increased expression of ERN1 protein]
CTD PMID:17963750, PMID:19139269, PMID:20493918, PMID:22378314, PMID:23576437, PMID:23885834, PMID:24224909, PMID:24638036, PMID:24898257, PMID:26264395, PMID:27587023, PMID:29414781, PMID:30796460 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Thapsigargin results in increased expression of ERO1A protein CTD PMID:28315715 NCBI chr15:19,619,947...19,655,381
Ensembl chr15:19,619,973...19,655,381
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta increases expression ISO Thapsigargin results in increased expression of ERO1B mRNA CTD PMID:22378314 NCBI chr17:90,709,394...90,783,110
Ensembl chr17:90,710,555...90,756,048
JBrowse link
G Erp44 endoplasmic reticulum protein 44 increases expression ISO Thapsigargin results in increased expression of ERP44 mRNA CTD PMID:22378314 NCBI chr 5:63,937,866...64,030,827
Ensembl chr 5:63,937,784...64,030,901
JBrowse link
G Esf1 ESF1 nucleolar pre-rRNA processing protein homolog increases expression ISO Thapsigargin results in increased expression of ESF1 protein CTD PMID:24648495 NCBI chr 3:133,178,591...133,232,358
Ensembl chr 3:133,178,561...133,232,322
JBrowse link
G Esrrg estrogen-related receptor gamma decreases expression ISO Thapsigargin results in decreased expression of ESRRG mRNA CTD PMID:22378314 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase decreases expression ISO Thapsigargin results in decreased expression of ETHE1 protein CTD PMID:24648495 NCBI chr 1:81,457,008...81,472,061
Ensembl chr 1:81,456,984...81,472,097
JBrowse link
G Etv4 ETS variant transcription factor 4 decreases expression ISO Thapsigargin results in decreased expression of ETV4 mRNA CTD PMID:22378314 NCBI chr10:89,685,058...89,700,300
Ensembl chr10:89,685,058...89,700,283
JBrowse link
G Etv5 ETS variant transcription factor 5 decreases expression ISO Thapsigargin results in decreased expression of ETV5 mRNA CTD PMID:22378314 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO Thapsigargin results in increased expression of EVI2A mRNA CTD PMID:24247028 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Thapsigargin results in decreased expression of EXO1 mRNA CTD PMID:22378314 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO Thapsigargin results in increased expression of EXOC4 protein CTD PMID:24648495 NCBI chr 4:60,549,128...61,358,305
Ensembl chr 4:60,549,197...61,355,994
JBrowse link
G Exosc2 exosome component 2 decreases expression ISO Thapsigargin results in decreased expression of EXOSC2 mRNA CTD PMID:24247028 NCBI chr 3:10,151,734...10,161,997
Ensembl chr 3:10,151,284...10,161,989
JBrowse link
G Exosc7 exosome component 7 affects expression ISO Thapsigargin affects the expression of EXOSC7 mRNA CTD PMID:24247028 NCBI chr 8:132,204,628...132,229,968
Ensembl chr 8:132,204,604...132,229,969
JBrowse link
G Ext2 exostosin glycosyltransferase 2 decreases expression ISO Thapsigargin results in decreased expression of EXT2 protein CTD PMID:24648495 NCBI chr 3:82,602,784...82,734,557
Ensembl chr 3:82,602,785...82,734,533
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Thapsigargin results in decreased expression of EYA1 protein CTD PMID:24648495 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G F2rl1 F2R like trypsin receptor 1 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of F2RL1 protein
Thapsigargin results in increased expression of F2RL1 mRNA
CTD PMID:24648495, PMID:29453283 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression ISO Thapsigargin results in increased expression of FADS1 mRNA CTD PMID:29453283 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO Thapsigargin results in increased expression of FADS3 mRNA CTD PMID:22378314 NCBI chr 1:226,091,774...226,108,332
Ensembl chr 1:226,091,774...226,108,332
JBrowse link
G Fam107b family with sequence similarity 107, member B increases expression
decreases expression
ISO Thapsigargin results in increased expression of FAM107B mRNA
Thapsigargin results in decreased expression of FAM107B protein
CTD PMID:22378314, PMID:24648495 NCBI chr17:78,489,667...78,689,933
Ensembl chr17:78,489,668...78,561,613
JBrowse link
G Fam118b family with sequence similarity 118, member B decreases expression ISO Thapsigargin results in decreased expression of FAM118B protein CTD PMID:24648495 NCBI chr 8:36,416,769...36,467,609
Ensembl chr 8:36,416,997...36,467,627
JBrowse link
G Fam120a family with sequence similarity 120A decreases expression ISO Thapsigargin results in decreased expression of FAM120A protein CTD PMID:24648495 NCBI chr17:16,106,101...16,196,054
Ensembl chr17:16,106,137...16,194,478
JBrowse link
G FAM120C family with sequence similarity 120C increases expression ISO Thapsigargin results in increased expression of FAM120C protein CTD PMID:24648495 NCBI chr  X:20,481,800...21,016,980
Ensembl chr  X:20,484,517...21,015,836
JBrowse link
G Fam13b family with sequence similarity 13, member B increases expression ISO Thapsigargin results in increased expression of FAM13B mRNA CTD PMID:29453283 NCBI chr18:27,223,345...27,304,462
Ensembl chr18:27,223,345...27,289,876
JBrowse link
G Fam174b family with sequence similarity 174, member B increases expression ISO Thapsigargin results in increased expression of FAM174B mRNA CTD PMID:29453283 NCBI chr 1:135,081,596...135,180,266
Ensembl chr 1:135,083,974...135,162,685
JBrowse link
G Fam193a family with sequence similarity 193, member A increases expression ISO Thapsigargin results in increased expression of FAM193A protein CTD PMID:24648495 NCBI chr14:81,515,897...81,638,919
Ensembl chr14:81,516,407...81,638,934
JBrowse link
G Fam234a family with sequence similarity 234, member A decreases expression ISO Thapsigargin results in decreased expression of FAM234A protein CTD PMID:24648495
G Fam83d family with sequence similarity 83, member D decreases expression ISO Thapsigargin results in decreased expression of FAM83D mRNA CTD PMID:22378314 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fanci FA complementation group I decreases expression ISO Thapsigargin results in decreased expression of FANCI mRNA CTD PMID:22378314 NCBI chr 1:141,116,565...141,172,997
Ensembl chr 1:141,120,166...141,172,483
JBrowse link
G Fbn2 fibrillin 2 increases expression ISO Thapsigargin results in increased expression of FBN2 mRNA CTD PMID:29453283 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO Thapsigargin results in decreased expression of FBP1 mRNA CTD PMID:22378314 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Thapsigargin results in increased expression of FBXO32 mRNA CTD PMID:22378314 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Thapsigargin results in decreased expression of FDFT1 mRNA CTD PMID:22378314 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Thapsigargin results in increased expression of FDXR mRNA CTD PMID:22378314 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fgf13 fibroblast growth factor 13 decreases expression ISO Thapsigargin results in decreased expression of FGF13 mRNA CTD PMID:19442820 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
increases expression
ISO indolo(3,2-b)carbazole inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]; N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [Thapsigargin results in increased expression of FGF21 mRNA] CTD PMID:27226639 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fggy FGGY carbohydrate kinase domain containing increases expression ISO Thapsigargin results in increased expression of FGGY mRNA CTD PMID:22378314 NCBI chr 5:114,516,860...114,901,571
Ensembl chr 5:114,516,889...114,901,564
JBrowse link
G Fh fumarate hydratase decreases expression ISO Thapsigargin results in decreased expression of FH mRNA CTD PMID:22378314 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Ficd FIC domain protein adenylyltransferase increases expression ISO Thapsigargin results in increased expression of FICD mRNA CTD PMID:22378314 NCBI chr12:48,658,283...48,663,175
Ensembl chr12:48,658,283...48,663,143
JBrowse link
G Fignl1 fidgetin-like 1 decreases expression ISO Thapsigargin results in decreased expression of FIGNL1 mRNA CTD PMID:22378314 NCBI chr14:91,895,902...91,904,474
Ensembl chr14:91,895,909...91,904,433
JBrowse link
G Filip1l filamin A interacting protein 1-like increases expression ISO Thapsigargin results in increased expression of FILIP1L protein CTD PMID:24648495 NCBI chr11:45,039,488...45,275,141
Ensembl chr11:45,039,461...45,124,423
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Thapsigargin results in increased expression of FIS1 mRNA CTD PMID:28940366 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Fjx1 four-jointed box kinase 1 decreases expression ISO Thapsigargin results in decreased expression of FJX1 mRNA CTD PMID:22378314 NCBI chr 3:92,288,818...92,290,919
Ensembl chr 3:92,288,818...92,290,919
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression ISO Thapsigargin results in increased expression of FKBP11 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 7:140,398,253...140,402,664
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 decreases expression ISO Thapsigargin results in decreased expression of FKBP3 protein CTD PMID:24648495 NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
JBrowse link
G Flii FLII, actin remodeling protein increases expression ISO Thapsigargin results in increased expression of FLII protein CTD PMID:24648495 NCBI chr10:46,955,460...46,969,468
Ensembl chr10:46,955,487...46,969,406
JBrowse link
G Flot2 flotillin 2 decreases expression ISO Thapsigargin results in decreased expression of FLOT2 mRNA CTD PMID:29453283 NCBI chr10:65,304,901...65,329,332
Ensembl chr10:65,304,902...65,329,312
JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 decreases expression
multiple interactions
ISO Thapsigargin results in decreased expression of FLRT2 mRNA
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLRT2 mRNA]
CTD PMID:19442820 NCBI chr 6:119,518,459...119,613,534
Ensembl chr 6:119,519,714...119,609,296
JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 multiple interactions ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of FLT4 mRNA] CTD PMID:19442820 NCBI chr10:35,078,782...35,120,296
Ensembl chr10:35,078,726...35,121,599
JBrowse link
G Fndc3b fibronectin type III domain containing 3B increases expression ISO Thapsigargin results in increased expression of FNDC3B mRNA CTD PMID:22378314 NCBI chr 2:113,109,949...113,415,171
Ensembl chr 2:113,112,902...113,345,577
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Thapsigargin results in increased expression of FOS mRNA CTD PMID:21694771, PMID:29453283 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Thapsigargin results in increased expression of FOSB mRNA CTD PMID:21694771, PMID:29453283 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Foxd2 forkhead box D2 decreases expression ISO Thapsigargin results in decreased expression of FOXD2 mRNA CTD PMID:29453283 NCBI chr 5:133,707,194...133,710,186
Ensembl chr 5:133,708,228...133,709,712
JBrowse link
G Foxo4 forkhead box O4 decreases expression ISO Thapsigargin results in decreased expression of FOXO4 mRNA CTD PMID:29453283 NCBI chr  X:71,155,284...71,162,158
Ensembl chr  X:71,155,601...71,162,158
JBrowse link
G Fundc2 FUN14 domain containing 2 decreases expression ISO Thapsigargin results in decreased expression of FUNDC2 protein CTD PMID:24648495 NCBI chr18:401,878...407,954
Ensembl chr18:402,295...407,954
JBrowse link
G Fzd7 frizzled class receptor 7 decreases expression ISO Thapsigargin results in decreased expression of FZD7 mRNA CTD PMID:22378314 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 decreases expression ISO Thapsigargin results in decreased expression of G3BP1 mRNA CTD PMID:22378314 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 affects localization EXP Thapsigargin affects the localization of GABBR1 protein CTD PMID:24668805 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 affects localization EXP Thapsigargin affects the localization of GABBR2 protein CTD PMID:24668805 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Thapsigargin results in increased expression of GADD45A mRNA CTD PMID:17332266, PMID:29453283 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Thapsigargin results in increased expression of GADD45B mRNA CTD PMID:29453283 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Thapsigargin results in increased expression of GADD45G mRNA CTD PMID:29453283 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression ISO Thapsigargin results in decreased expression of GAL mRNA CTD PMID:22378314 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galk2 galactokinase 2 increases expression ISO Thapsigargin results in increased expression of GALK2 mRNA CTD PMID:22378314 NCBI chr 3:118,137,097...118,268,838
Ensembl chr 3:118,136,838...118,268,836
JBrowse link
G Galr2 galanin receptor 2 increases expression ISO Thapsigargin results in increased expression of GALR2 mRNA CTD PMID:29453283 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Ganab glucosidase II alpha subunit increases expression ISO Thapsigargin results in increased expression of GANAB mRNA
Thapsigargin results in increased expression of GANAB protein
CTD PMID:22378314, PMID:24648495 NCBI chr 1:225,096,558...225,116,384
Ensembl chr 1:225,096,598...225,116,378
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Thapsigargin results in decreased expression of GAP43 mRNA CTD PMID:22378314 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gars glycyl-tRNA synthetase increases expression ISO Thapsigargin results in increased expression of GARS1 mRNA; Thapsigargin results in increased expression of GARS1 protein CTD PMID:22378314, PMID:29453283 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas1 growth arrest-specific 1 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of GAS1 protein
Thapsigargin results in increased expression of GAS1 mRNA
CTD PMID:24648495, PMID:29453283 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gata2 GATA binding protein 2 decreases expression ISO Thapsigargin results in decreased expression of GATA2 mRNA CTD PMID:22378314 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Gcat glycine C-acetyltransferase decreases expression ISO Thapsigargin results in decreased expression of GCAT mRNA CTD PMID:22378314 NCBI chr 7:120,263,068...120,269,365
Ensembl chr 7:120,263,054...120,269,451
JBrowse link
G Gcdh glutaryl-CoA dehydrogenase decreases expression ISO Thapsigargin results in decreased expression of GCDH mRNA CTD PMID:22378314 NCBI chr19:26,000,497...26,006,970
Ensembl chr19:26,000,497...26,006,970
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Thapsigargin results in increased expression of GDF15 mRNA CTD PMID:22378314 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Thapsigargin results in increased expression of GEM mRNA CTD PMID:21694771, PMID:29453283 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 decreases expression ISO Thapsigargin results in decreased expression of GEMIN4 mRNA CTD PMID:24247028 NCBI chr10:64,364,808...64,375,885
Ensembl chr10:64,368,809...64,375,816
JBrowse link
G Gemin5 gem (nuclear organelle) associated protein 5 increases expression ISO Thapsigargin results in increased expression of GEMIN5 protein CTD PMID:24648495 NCBI chr10:43,552,260...43,599,241
Ensembl chr10:43,554,046...43,599,232
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 decreases expression ISO Thapsigargin results in decreased expression of GFM1 mRNA CTD PMID:22378314 NCBI chr 2:164,601,575...164,646,478
Ensembl chr 2:164,601,586...164,646,439
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 increases expression ISO Thapsigargin results in increased expression of GFPT1 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 4:118,852,046...118,901,583
Ensembl chr 4:118,852,062...118,901,591
JBrowse link
G Ggct gamma-glutamyl cyclotransferase decreases expression ISO Thapsigargin results in decreased expression of GGCT protein CTD PMID:24648495 NCBI chr 4:85,186,644...85,192,857
Ensembl chr 4:85,186,644...85,192,834
JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO Thapsigargin results in decreased expression of GINS2 mRNA CTD PMID:22378314 NCBI chr19:54,151,048...54,163,701
Ensembl chr19:54,151,048...54,163,608
JBrowse link
G Gla galactosidase, alpha increases expression ISO Thapsigargin results in increased expression of GLA mRNA CTD PMID:29453283 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Gldc glycine decarboxylase decreases expression ISO Thapsigargin results in decreased expression of GLDC mRNA CTD PMID:22378314 NCBI chr 1:248,295,140...248,377,122
Ensembl chr 1:248,297,331...248,377,093
JBrowse link
G Glg1 golgi glycoprotein 1 increases expression ISO Thapsigargin results in increased expression of GLG1 protein CTD PMID:24648495 NCBI chr19:42,983,879...43,088,074
Ensembl chr19:42,983,869...43,090,841
JBrowse link
G Glo1 glyoxalase 1 decreases expression ISO Thapsigargin results in decreased expression of GLO1 protein CTD PMID:24648495 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glrx3 glutaredoxin 3 decreases expression ISO Thapsigargin results in decreased expression of GLRX3 protein CTD PMID:24648495 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gls glutaminase increases expression ISO Thapsigargin results in increased expression of GLS mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gmeb1 glucocorticoid modulatory element binding protein 1 decreases expression ISO Thapsigargin results in decreased expression of GMEB1 mRNA CTD PMID:22378314 NCBI chr 5:150,408,075...150,449,252
Ensembl chr 5:150,405,918...150,439,959
JBrowse link
G Gmnn geminin, DNA replication inhibitor decreases expression ISO Thapsigargin results in decreased expression of GMNN mRNA CTD PMID:22378314 NCBI chr17:42,302,523...42,310,783
Ensembl chr17:42,302,540...42,310,783
JBrowse link
G Gmppa GDP-mannose pyrophosphorylase A increases expression ISO Thapsigargin results in increased expression of GMPPA mRNA CTD PMID:22378314 NCBI chr 9:82,632,267...82,639,811
Ensembl chr 9:82,632,230...82,639,821
JBrowse link
G Gng12 G protein subunit gamma 12 decreases expression ISO Thapsigargin results in decreased expression of GNG12 mRNA CTD PMID:29453283 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Gng2 G protein subunit gamma 2 decreases expression ISO Thapsigargin results in decreased expression of GNG2 mRNA CTD PMID:22378314 NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555
JBrowse link
G Gnl3l G protein nucleolar 3 like increases expression ISO Thapsigargin results in increased expression of GNL3L mRNA CTD PMID:22378314 NCBI chr  X:20,037,558...20,070,505
Ensembl chr  X:20,034,882...20,070,578
JBrowse link
G Golga2 golgin A2 increases expression ISO Thapsigargin results in increased expression of GOLGA2 mRNA CTD PMID:22378314 NCBI chr 3:11,317,328...11,337,569
Ensembl chr 3:11,317,183...11,336,458
JBrowse link
G Golga3 golgin A3 increases expression ISO Thapsigargin results in increased expression of GOLGA3 mRNA CTD PMID:22378314 NCBI chr12:52,510,509...52,558,606
Ensembl chr12:52,512,970...52,558,606
JBrowse link
G Golga5 golgin A5 increases expression ISO Thapsigargin results in increased expression of GOLGA5 mRNA CTD PMID:22378314 NCBI chr 6:126,350,572...126,378,735
Ensembl chr 6:126,353,223...126,378,610
JBrowse link
G Gosr1 golgi SNAP receptor complex member 1 decreases expression ISO Thapsigargin results in decreased expression of GOSR1 mRNA CTD PMID:19442820 NCBI chr10:63,405,526...63,442,257
Ensembl chr10:63,405,586...63,442,250
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Thapsigargin results in decreased expression of GOT2 mRNA CTD PMID:22378314 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression ISO Thapsigargin results in increased expression of GPD2 protein CTD PMID:24648495 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gpr137b G protein-coupled receptor 137B decreases expression ISO Thapsigargin results in decreased expression of GPR137B mRNA CTD PMID:29453283 NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
JBrowse link
G Gpr22 G protein-coupled receptor 22 increases expression ISO Thapsigargin results in increased expression of GPR22 mRNA CTD PMID:22378314 NCBI chr 6:51,012,421...51,021,253
Ensembl chr 6:51,011,426...51,019,407
JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B decreases expression ISO Thapsigargin results in decreased expression of GPRC5B protein CTD PMID:24648495 NCBI chr 1:188,688,743...188,713,724
Ensembl chr 1:188,688,743...188,713,280
JBrowse link
G Gps2 G protein pathway suppressor 2 increases expression ISO Thapsigargin results in increased expression of GPS2 mRNA CTD PMID:22378314 NCBI chr10:56,524,327...56,527,447
Ensembl chr10:56,524,468...56,526,987
JBrowse link
G Gpsm2 G-protein signaling modulator 2 decreases expression ISO Thapsigargin results in decreased expression of GPSM2 mRNA CTD PMID:22378314 NCBI chr 2:211,480,120...211,528,096
Ensembl chr 2:211,480,400...211,527,919
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Thapsigargin results in increased expression of GPT2 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gpx8 glutathione peroxidase 8 increases expression ISO Thapsigargin results in increased expression of GPX8 mRNA CTD PMID:29453283 NCBI chr 2:44,903,337...44,907,046
Ensembl chr 2:44,903,337...44,907,030
JBrowse link
G Grcc10 gene rich cluster, C10 gene increases expression ISO Thapsigargin results in increased expression of C12ORF57 mRNA CTD PMID:29453283 NCBI chr 4:157,264,383...157,266,042
Ensembl chr 4:157,264,383...157,266,018
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Thapsigargin results in decreased expression of GRPEL1 mRNA CTD PMID:22378314 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Grpel2 GrpE-like 2, mitochondrial increases expression ISO Thapsigargin results in increased expression of GRPEL2 mRNA CTD PMID:22378314 NCBI chr18:57,037,995...57,050,234
Ensembl chr18:57,036,877...57,050,408
JBrowse link
G Gsdmd gasdermin D increases expression ISO Thapsigargin results in increased expression of GSDMD mRNA CTD PMID:30796460 NCBI chr 7:116,889,147...116,894,134
Ensembl chr 7:116,889,572...116,894,134
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of GSR mRNA] CTD PMID:19442820 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression
decreases expression
ISO Thapsigargin results in increased expression of H1-2 mRNA
Thapsigargin results in decreased expression of H1F2 protein
CTD PMID:22378314, PMID:24648495 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO Thapsigargin results in decreased expression of H1F4 protein CTD PMID:24648495 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Thapsigargin results in increased expression of H2AC20 mRNA CTD PMID:29453283 NCBI chr 2:198,360,271...198,360,735
Ensembl chr 2:198,360,301...198,360,678
JBrowse link
G H2ax H2A.X variant histone increases expression
decreases phosphorylation
ISO Thapsigargin results in increased expression of H2AX mRNA
Thapsigargin results in decreased phosphorylation of H2AX protein
CTD PMID:19442820, PMID:32482060 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression ISO Thapsigargin results in increased expression of HADHA protein CTD PMID:24648495 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 increases expression ISO Thapsigargin results in increased expression of HAVCR2 mRNA CTD PMID:22378314 NCBI chr10:31,561,838...31,590,624
Ensembl chr10:31,561,895...31,588,943
JBrowse link
G Hax1 HCLS1 associated protein X-1 increases expression ISO Thapsigargin results in increased expression of HAX1 mRNA CTD PMID:22378314 NCBI chr 2:189,330,900...189,333,305
Ensembl chr 2:189,330,902...189,333,322
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Thapsigargin results in increased expression of HBEGF mRNA CTD PMID:29453283 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hbq1b hemoglobin subunit theta 1B decreases expression ISO Thapsigargin results in decreased expression of HBQ1 mRNA CTD PMID:22378314 NCBI chr10:15,599,821...15,602,680
Ensembl chr10:15,600,220...15,600,858
JBrowse link
G Hcfc1 host cell factor C1 increases expression ISO Thapsigargin results in increased expression of HCFC1 protein CTD PMID:24648495 NCBI chr  X:156,812,012...156,837,227
Ensembl chr  X:156,812,064...156,837,227
JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Thapsigargin results in increased expression of HDAC5 mRNA CTD PMID:22378314 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hdac6 histone deacetylase 6 increases expression ISO Thapsigargin results in increased expression of HDAC6 protein CTD PMID:24648495 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hdgf heparin binding growth factor multiple interactions
increases expression
ISO Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of HDGF mRNA] CTD PMID:19442820 NCBI chr 2:187,274,898...187,284,670
Ensembl chr 2:187,275,120...187,284,281
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 increases expression ISO Thapsigargin results in increased expression of HECTD1 protein CTD PMID:24648495 NCBI chr 6:72,509,658...72,596,285
Ensembl chr 6:72,510,255...72,596,446
JBrowse link
G Helb DNA helicase B increases expression ISO Thapsigargin results in increased expression of HELB protein CTD PMID:24648495 NCBI chr 7:64,860,641...64,888,146
Ensembl chr 7:64,860,666...64,887,448
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Thapsigargin results in increased expression of HERPUD1 mRNA CTD PMID:22378314, PMID:27587023, PMID:29453283 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO Thapsigargin results in decreased expression of HES1 mRNA CTD PMID:29453283 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression ISO Thapsigargin results in decreased expression of HES6 mRNA CTD PMID:22378314 NCBI chr 9:98,549,698...98,551,438
Ensembl chr 9:98,549,705...98,551,438
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 decreases expression ISO Thapsigargin results in decreased expression of HEY1 mRNA CTD PMID:22378314 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
EXP Thapsigargin results in decreased expression of HGF mRNA; Thapsigargin results in decreased expression of HGF protein
4-phenylbutyric acid inhibits the reaction [Thapsigargin results in decreased expression of HGF mRNA]; salubrinal inhibits the reaction [Thapsigargin results in decreased expression of HGF mRNA]; salubrinal inhibits the reaction [Thapsigargin results in decreased expression of HGF protein]
CTD PMID:28844859 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hgsnat heparan-alpha-glucosaminide N-acetyltransferase decreases expression ISO Thapsigargin results in decreased expression of HGSNAT protein CTD PMID:24648495 NCBI chr16:70,876,557...70,909,443 JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase decreases expression ISO Thapsigargin results in decreased expression of HIBADH mRNA CTD PMID:22378314 NCBI chr 4:82,604,369...82,702,429
Ensembl chr 4:82,604,373...82,702,429
JBrowse link
G Hid1 HID1 domain containing increases expression ISO Thapsigargin results in increased expression of HID1 mRNA CTD PMID:22378314 NCBI chr10:103,899,160...103,919,649
Ensembl chr10:103,899,150...103,919,605
JBrowse link
G Hikeshi heat shock protein nuclear import factor decreases expression ISO Thapsigargin results in decreased expression of HIKESHI protein CTD PMID:24648495 NCBI chr 1:154,147,098...154,170,429
Ensembl chr 1:154,142,836...154,170,409
JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 increases expression ISO Thapsigargin results in increased expression of H2AC18 mRNA CTD PMID:29453283 NCBI chr 2:198,388,766...198,389,293
Ensembl chr 2:198,388,809...198,389,201
Ensembl chr 2:198,388,809...198,389,201
JBrowse link
G Hk1 hexokinase 1 increases expression ISO Thapsigargin results in increased expression of HK1 protein CTD PMID:24648495 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hk2 hexokinase 2 increases expression
decreases expression
ISO Thapsigargin results in increased expression of HK2 mRNA
Thapsigargin results in decreased expression of HK2 mRNA
CTD PMID:21694771, PMID:22378314 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Hlcs holocarboxylase synthetase increases expression ISO Thapsigargin results in increased expression of HLCS mRNA CTD PMID:22378314 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hltf helicase-like transcription factor increases expression ISO Thapsigargin results in increased expression of HLTF protein CTD PMID:24648495 NCBI chr 2:104,854,571...104,914,338
Ensembl chr 2:104,854,572...104,914,173
JBrowse link
G Hm13 histocompatibility minor 13 increases expression ISO Thapsigargin results in increased expression of HM13 mRNA CTD PMID:22378314 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G Hmbs hydroxymethylbilane synthase decreases expression ISO Thapsigargin results in decreased expression of HMBS protein CTD PMID:24648495 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase increases expression ISO Thapsigargin results in increased expression of HMGCL mRNA CTD PMID:22378314 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression
increases expression
ISO Thapsigargin results in decreased expression of HMGCR mRNA
Thapsigargin results in increased expression of HMGCR mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of HMGCS1 mRNA
Thapsigargin results in increased expression of HMGCS1 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Thapsigargin results in increased expression of HMOX1 mRNA CTD PMID:29453283 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmx1 H6 family homeobox 1 decreases expression ISO Thapsigargin results in decreased expression of HMX1 mRNA CTD PMID:22378314 NCBI chr14:80,540,558...80,544,607
Ensembl chr14:80,541,075...80,544,342
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions
ISO Thapsigargin results in decreased expression of HNF4A mRNA; Thapsigargin results in decreased expression of HNF4A protein
Thapsigargin promotes the reaction [HNF4A protein binds to NR1I2 promoter]
CTD PMID:25616597 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions
affects localization
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Thapsigargin affects the localization of HNRNPA1 protein]; Thapsigargin promotes the reaction [HNRNPA1 protein binds to SREBF1 5' UTR] CTD PMID:23106379 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Thapsigargin results in decreased expression of HNRNPA2B1 mRNA CTD PMID:22378314 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 decreases expression ISO Thapsigargin results in decreased expression of HNRNPA3 mRNA CTD PMID:22378314 NCBI chr 3:62,481,222...62,491,356
Ensembl chr 3:62,481,323...62,487,227
JBrowse link
G Hook3 hook microtubule-tethering protein 3 increases expression ISO Thapsigargin results in increased expression of HOOK3 protein CTD PMID:24648495 NCBI chr16:70,710,347...70,818,789 JBrowse link
G Hoxa10 homeobox A10 decreases expression ISO Thapsigargin results in decreased expression of HOXA10 mRNA CTD PMID:29453283 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Hoxa11-as HOXA11 antisense RNA decreases expression ISO Thapsigargin results in decreased expression of HOXA11-AS mRNA CTD PMID:29453283
G Hoxa13 homeo box A13 decreases expression ISO Thapsigargin results in decreased expression of HOXA13 mRNA CTD PMID:29453283 Ensembl chr 4:82,228,017...82,229,397 JBrowse link
G Hoxb5 homeo box B5 decreases expression ISO Thapsigargin results in decreased expression of HOXB5 mRNA CTD PMID:29453283 NCBI chr10:84,152,152...84,154,360
Ensembl chr10:84,152,152...84,154,360
JBrowse link
G Hoxc13 homeobox C13 decreases expression ISO Thapsigargin results in decreased expression of HOXC13 mRNA CTD PMID:29453283 NCBI chr 7:144,531,814...144,538,298
Ensembl chr 7:144,531,814...144,537,966
JBrowse link
G Hoxc8 homeobox C8 decreases expression ISO Thapsigargin results in decreased expression of HOXC8 mRNA CTD PMID:29453283 NCBI chr 7:144,605,072...144,607,639
Ensembl chr 7:144,605,058...144,608,538
JBrowse link
G Hoxc9 homeobox C9 decreases expression ISO Thapsigargin results in decreased expression of HOXC9 mRNA CTD PMID:29453283 NCBI chr 7:144,592,462...144,598,807
Ensembl chr 7:144,595,960...144,598,632
JBrowse link
G Hpca hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Thapsigargin CTD PMID:15607944 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression ISO Thapsigargin results in decreased expression of HPRT1 mRNA CTD PMID:22378314 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor affects response to substance
multiple interactions
ISO HR protein affects the susceptibility to Thapsigargin
HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein]
CTD PMID:20886113 NCBI chr15:52,241,801...52,261,276
Ensembl chr15:52,241,801...52,261,276
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Thapsigargin co-treated with HRAS protein] results in decreased phosphorylation of MAPK1 protein; [Thapsigargin co-treated with HRAS protein] results in decreased phosphorylation of MAPK3 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of EIF2AK3 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of ERN1 protein; [Thapsigargin co-treated with HRAS protein] results in increased expression of HSPA5 protein; [Thapsigargin co-treated with HRAS protein] results in increased phosphorylation of AKT1 protein CTD PMID:24898257 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone increases expression ISO Thapsigargin results in increased expression of HSCB mRNA CTD PMID:22378314 NCBI chr12:51,878,267...51,888,645
Ensembl chr12:51,878,153...51,888,669
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Thapsigargin results in decreased expression of HSD17B10 mRNA CTD PMID:22378314 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression ISO Thapsigargin results in decreased expression of HSP90AA1 mRNA CTD PMID:22378314 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions
decreases expression
increases expression
ISO
EXP
Apigenin inhibits the reaction [Thapsigargin results in increased expression of HSP90B1 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of HSP90B1 protein]
Thapsigargin results in decreased expression of HSP90B1 mRNA
4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of HSP90B1 mRNA]
Thapsigargin results in increased expression of HSP90B1 mRNA; Thapsigargin results in increased expression of HSP90B1 protein
CTD PMID:15292203, PMID:17416481, PMID:19442820, PMID:20493918, PMID:22378314, PMID:27587023, PMID:27638049, PMID:29453283 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Thapsigargin results in decreased expression of HSPA1B mRNA CTD PMID:22378314 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases expression ISO Thapsigargin results in decreased expression of HSPA1L mRNA CTD PMID:22378314 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; ATF6 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; EIF2AK3 promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Quercetin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [pterostilbene results in increased expression of HSPA5 protein]; wortmannin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]
Thapsigargin results in increased expression of HSPA5 mRNA; Thapsigargin results in increased expression of HSPA5 protein
Thapsigargin results in increased expression of HSPA5; Thapsigargin results in increased expression of HSPA5 mRNA; Thapsigargin results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; GW 506033X inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]
[Thapsigargin co-treated with HRAS protein] results in increased expression of HSPA5 protein; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Apigenin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Glutathione inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of HSPA5 protein]; Thapsigargin promotes the reaction [arsenic trioxide results in increased expression of HSPA5 protein]; Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]
CTD PMID:12147617, PMID:12198651, PMID:14610226, PMID:15019097, PMID:16236328, PMID:16298333, PMID:16338971, PMID:17283163, PMID:17332266, PMID:17353921, PMID:17416481, PMID:17475668, PMID:17915553, PMID:18477628, PMID:18799549, PMID:19135031, PMID:19139269, PMID:19428936, PMID:20477944, PMID:20493918, PMID:20589738, PMID:20626587, PMID:21198628, PMID:21320468, PMID:21692457, PMID:21694771, PMID:22378314, PMID:22425709, PMID:22509299, PMID:22800509, PMID:23885834, PMID:24898257, PMID:25324550, PMID:25341683, PMID:25611565, PMID:26085089, PMID:26264395, PMID:27358234, PMID:27578021, PMID:27587023, PMID:27638049, PMID:28223344, PMID:28315715, PMID:28844859, PMID:29126784, PMID:29453283, PMID:32574669 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Thapsigargin results in decreased expression of HSPA8 mRNA CTD PMID:22378314 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of HSPA9 protein
Thapsigargin results in increased expression of HSPA9 mRNA
CTD PMID:21692457, PMID:22378314, PMID:28942281 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of HSPD1 mRNA
Thapsigargin results in increased expression of HSPD1 mRNA
CTD PMID:22378314, PMID:28942281 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions
decreases expression
increases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of HSPE1 mRNA]
Thapsigargin results in decreased expression of HSPE1 mRNA
CTD PMID:19442820, PMID:22378314 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Thapsigargin results in increased expression of HSPH1 protein CTD PMID:24648495 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 decreases expression ISO Thapsigargin results in decreased expression of HTATIP2 protein CTD PMID:24648495 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases activity ISO Thapsigargin results in increased activity of HTR1A protein CTD PMID:11356925 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Hyou1 hypoxia up-regulated 1 increases expression ISO Thapsigargin results in increased expression of HYOU1 mRNA; Thapsigargin results in increased expression of HYOU1 protein CTD PMID:22378314, PMID:29453283 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Ibtk inhibitor of Bruton tyrosine kinase multiple interactions
increases expression
ISO ATF4 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]; EIF2S1 protein mutant form inhibits the reaction [Thapsigargin results in increased expression of IBTK mRNA alternative form]
Thapsigargin results in increased expression of IBTK protein
CTD PMID:24648495 NCBI chr 8:93,323,454...93,397,044
Ensembl chr 8:93,324,476...93,390,305
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Thapsigargin results in increased expression of ID2 mRNA CTD PMID:22378314 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO Thapsigargin results in decreased expression of ID3 mRNA CTD PMID:29453283 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha increases expression ISO Thapsigargin results in increased expression of IDH3A mRNA CTD PMID:22378314 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO Thapsigargin results in decreased expression of IFITM2 protein CTD PMID:24648495 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression ISO Thapsigargin results in increased expression of IFRD1 mRNA CTD PMID:29453283 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ift20 intraflagellar transport 20 increases expression ISO Thapsigargin results in increased expression of IFT20 mRNA CTD PMID:22378314 NCBI chr10:65,805,808...65,811,353
Ensembl chr10:65,805,860...65,811,351
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression ISO Thapsigargin results in decreased expression of IGFBP2 mRNA CTD PMID:22378314 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Thapsigargin results in increased expression of IGFBP3 mRNA CTD PMID:22378314 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Thapsigargin results in decreased expression of IGFBP4 protein CTD PMID:24648495 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 increases expression
decreases expression
ISO Thapsigargin results in increased expression of IGFBP5 mRNA
Thapsigargin results in decreased expression of IGFBP5 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il18 interleukin 18 increases expression ISO Thapsigargin results in increased expression of IL18 mRNA CTD PMID:30796460 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Thapsigargin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]
Thapsigargin results in increased expression of IL1B mRNA
CTD PMID:18799549, PMID:30796460 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il21r interleukin 21 receptor multiple interactions ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA]; caffeic acid promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in decreased expression of IL21R mRNA] CTD PMID:19442820 NCBI chr 1:196,996,405...197,024,185
Ensembl chr 1:196,996,581...197,024,166
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Thapsigargin inhibits the reaction [bisphenol A results in increased expression of IL4 protein]; Thapsigargin inhibits the reaction [nonylphenol results in increased expression of IL4 protein] CTD PMID:12709020 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
EXP
ISO
Thapsigargin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
Thapsigargin results in increased expression of IL6 mRNA
Thapsigargin promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:18951912, PMID:19285962, PMID:20682585, PMID:21694771, PMID:25616597 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer decreases expression EXP Thapsigargin results in decreased expression of IL6ST protein CTD PMID:19285962 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha increases expression ISO Thapsigargin results in increased expression of INA mRNA CTD PMID:29453283 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Incenp inner centromere protein increases expression ISO Thapsigargin results in increased expression of INCENP protein CTD PMID:24648495 NCBI chr 1:225,923,448...225,953,384
Ensembl chr 1:225,925,773...225,952,516
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO Thapsigargin results in increased expression of INHBA mRNA CTD PMID:21694771 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Thapsigargin results in increased expression of INHBE mRNA CTD PMID:22935518 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Thapsigargin inhibits the reaction [ferric ammonium citrate inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]]; Thapsigargin inhibits the reaction [NCOA4 protein inhibits the reaction [Palmitic Acid inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]]] CTD PMID:32283200 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig1 insulin induced gene 1 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of INSIG1 mRNA
Thapsigargin results in increased expression of INSIG1 mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insm2 INSM transcriptional repressor 2 decreases expression ISO Thapsigargin results in decreased expression of INSM2 mRNA CTD PMID:22378314 NCBI chr 6:76,380,681...76,386,240
Ensembl chr 6:76,383,446...76,384,933
JBrowse link
G Ints4 integrator complex subunit 4 increases expression ISO Thapsigargin results in increased expression of INTS4 protein CTD PMID:24648495 NCBI chr 1:162,447,692...162,511,350
Ensembl chr 1:162,447,680...162,511,355
JBrowse link
G Ints6 integrator complex subunit 6 increases expression ISO Thapsigargin results in increased expression of INTS6 protein CTD PMID:24648495 NCBI chr15:45,844,050...45,929,996
Ensembl chr15:45,858,608...45,947,030
JBrowse link
G Ipo5 importin 5 increases expression ISO Thapsigargin results in increased expression of IPO5 protein CTD PMID:24648495 NCBI chr15:106,243,110...106,293,326
Ensembl chr15:106,257,650...106,292,112
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO Thapsigargin results in increased expression of IQGAP1 protein CTD PMID:24648495 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO Thapsigargin results in increased expression of IRF7 mRNA CTD PMID:22378314 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO Thapsigargin affects the phosphorylation of and results in decreased expression of IRS1 protein CTD PMID:22378314 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irx3 iroquois homeobox 3 decreases expression ISO Thapsigargin results in decreased expression of IRX3 mRNA CTD PMID:29453283 NCBI chr19:15,838,714...15,842,135
Ensembl chr19:15,838,714...15,840,990
JBrowse link
G Iscu iron-sulfur cluster assembly enzyme increases expression ISO Thapsigargin results in increased expression of ISCU mRNA CTD PMID:22378314 NCBI chr12:48,621,454...48,627,297
Ensembl chr12:48,621,454...48,627,297
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Thapsigargin results in increased expression of ISG15 mRNA CTD PMID:29453283 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 decreases expression ISO Thapsigargin results in decreased expression of ISLR2 mRNA CTD PMID:22378314 NCBI chr 8:62,983,333...62,991,401
Ensembl chr 8:62,984,552...62,987,182
JBrowse link
G Isoc1 isochorismatase domain containing 1 decreases expression ISO Thapsigargin results in decreased expression of ISOC1 mRNA
Thapsigargin results in decreased expression of ISOC1 protein
CTD PMID:22378314, PMID:24648495 NCBI chr18:53,727,203...53,747,612
Ensembl chr18:53,727,209...53,745,200
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Thapsigargin results in decreased expression of ITGB5 protein CTD PMID:24648495 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO Thapsigargin results in increased expression of ITPR1 mRNA CTD PMID:28223344 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases expression ISO Thapsigargin results in increased expression of ITPR2 mRNA CTD PMID:28223344 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 decreases expression ISO Thapsigargin results in decreased expression of ITPR3 mRNA CTD PMID:22378314 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
JBrowse link
G Itpripl2 ITPRIP like 2 decreases expression ISO Thapsigargin results in decreased expression of ITPRIPL2 mRNA CTD PMID:29453283 NCBI chr 1:188,140,853...188,142,748
Ensembl chr 1:188,141,113...188,142,721
JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Thapsigargin results in increased expression of JAK1 protein CTD PMID:24648495 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Jkamp JNK1/MAPK8-associated membrane protein decreases expression ISO Thapsigargin results in decreased expression of JKAMP protein CTD PMID:24648495 NCBI chr 6:94,835,845...94,849,784
Ensembl chr 6:94,835,845...94,849,784
JBrowse link
G Jmjd4 jumonji domain containing 4 decreases expression ISO Thapsigargin results in decreased expression of JMJD4 protein CTD PMID:24648495 NCBI chr10:45,798,964...45,804,188
Ensembl chr10:45,798,797...45,804,541
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 decreases expression ISO Thapsigargin results in decreased expression of JPT1 protein CTD PMID:24648495 NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases phosphorylation
increases expression
ISO Thapsigargin results in decreased phosphorylation of JUN protein
Thapsigargin results in increased expression of JUN mRNA
CTD PMID:23576437, PMID:29453283 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Thapsigargin analog results in increased expression of JUNB mRNA]
Thapsigargin results in increased expression of JUNB mRNA
CTD PMID:8764118 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit increases expression ISO Thapsigargin results in increased expression of JUND mRNA CTD PMID:29453283 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kank2 KN motif and ankyrin repeat domains 2 decreases expression ISO Thapsigargin results in decreased expression of KANK2 mRNA CTD PMID:22378314 NCBI chr 8:22,792,000...22,821,459
Ensembl chr 8:22,791,995...22,821,397
JBrowse link
G Kank4 KN motif and ankyrin repeat domains 4 increases expression ISO Thapsigargin results in increased expression of KANK4 mRNA CTD PMID:22378314 NCBI chr 5:117,376,425...117,440,643
Ensembl chr 5:117,376,423...117,440,254
JBrowse link
G Kat2a lysine acetyltransferase 2A decreases expression ISO Thapsigargin results in decreased expression of KAT2A protein CTD PMID:24648495 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 increases expression ISO Thapsigargin results in increased expression of KCNJ2 mRNA CTD PMID:22378314 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 decreases expression ISO Thapsigargin results in decreased expression of KCNK1 mRNA CTD PMID:22378314 NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 increases expression ISO Thapsigargin results in increased expression of KCNK12 mRNA CTD PMID:29453283 NCBI chr 6:11,373,917...11,494,459
Ensembl chr 6:11,373,917...11,494,459
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression ISO Thapsigargin results in increased expression of KCNN4 mRNA CTD PMID:19442820 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 increases expression ISO Thapsigargin results in increased expression of KCTD12 mRNA CTD PMID:19442820 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Kctd20 potassium channel tetramerization domain containing 20 decreases expression ISO Thapsigargin results in decreased expression of KCTD20 protein CTD PMID:24648495 NCBI chr20:6,205,897...6,222,818
Ensembl chr20:6,205,903...6,219,936
JBrowse link
G Kctd3 potassium channel tetramerization domain containing 3 decreases expression ISO Thapsigargin results in decreased expression of KCTD3 protein CTD PMID:24648495 NCBI chr13:107,433,588...107,471,843
Ensembl chr13:107,433,588...107,471,843
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 increases expression ISO Thapsigargin results in increased expression of KDELR2 mRNA CTD PMID:22378314 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Thapsigargin results in increased expression of KEAP1 protein CTD PMID:27358234 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif11 kinesin family member 11 decreases expression
increases expression
ISO Thapsigargin results in decreased expression of KIF11 mRNA
Thapsigargin results in increased expression of KIF11 protein
CTD PMID:22378314, PMID:24648495 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif15 kinesin family member 15 multiple interactions
increases expression
ISO [Thapsigargin co-treated with 4-methoxycinnamate methyl ester] results in increased expression of KIF15 mRNA; [Thapsigargin co-treated with caffeic acid] results in increased expression of KIF15 mRNA; [Thapsigargin co-treated with Drugs, Chinese Herbal] results in increased expression of KIF15 mRNA
Thapsigargin results in increased expression of KIF15 mRNA
CTD PMID:19442820 NCBI chr 8:132,033,117...132,103,528
Ensembl chr 8:132,032,944...132,103,927
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Thapsigargin results in decreased expression of KIF20A mRNA CTD PMID:22378314 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif20b kinesin family member 20B multiple interactions
increases expression
ISO 4-methoxycinnamate methyl ester promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]; caffeic acid promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA]; Drugs, Chinese Herbal promotes the reaction [Thapsigargin results in increased expression of KIF20B mRNA] CTD PMID:19442820 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kif24 kinesin family member 24 decreases expression ISO Thapsigargin results in decreased expression of KIF24 protein CTD PMID:24648495 NCBI chr 5:57,778,730...57,845,642
Ensembl chr 5:57,780,389...57,845,509
JBrowse link
G Kif2c kinesin family member 2C multiple interactions
increases expression
ISO 4-methoxycinnamate methyl ester inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA]; caffeic acid inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA]; Drugs, Chinese Herbal inhibits the reaction [Thapsigargin results in increased expression of KIF2C mRNA] CTD PMID:19442820 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO Thapsigargin results in decreased expression of KIF4A mRNA CTD PMID:22378314 NCBI chr  X:70,461,700...70,561,084
Ensembl chr  X:70,461,718...70,561,189
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO Thapsigargin results in increased expression of KIT mRNA CTD PMID:22378314 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO Thapsigargin results in decreased expression of KLC1 protein CTD PMID:24648495 NCBI chr 6:136,330,151...136,373,716
Ensembl chr 6:136,330,383...136,373,721
JBrowse link
G Klhl13 kelch-like family member 13 decreases expression ISO Thapsigargin results in decreased expression of KLHL13 mRNA CTD PMID:22378314 NCBI chr  X:121,578,965...121,735,014
Ensembl chr  X:121,578,940...121,731,543
JBrowse link
G Krt19 keratin 19 decreases expression ISO Thapsigargin results in decreased expression of KRT19 mRNA CTD PMID:29453283 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Krt8 keratin 8 decreases expression ISO Thapsigargin results in decreased expression of KRT8 protein CTD PMID:21692457 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Krtcap2 keratinocyte associated protein 2 increases expression ISO Thapsigargin results in increased expression of KRTCAP2 mRNA CTD PMID:22378314, PMID:29453283 NCBI chr 2:188,561,548...188,565,544
Ensembl chr 2:188,561,429...188,565,544
JBrowse link
G Ktn1 kinectin 1 increases expression ISO Thapsigargin results in increased expression of KTN1 protein CTD PMID:24648495 NCBI chr15:24,465,761...24,552,833
Ensembl chr15:24,479,761...24,553,197
JBrowse link
G Lama1 laminin subunit alpha 1 decreases expression ISO Thapsigargin results in decreased expression of LAMA1 mRNA CTD PMID:22378314 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lama5 laminin subunit alpha 5 decreases expression ISO Thapsigargin results in decreased expression of LAMA5 mRNA CTD PMID:29453283 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Lamb1 laminin subunit beta 1 increases expression ISO Thapsigargin results in increased expression of LAMB1 mRNA
Thapsigargin results in increased expression of LAMB1 protein
CTD PMID:22378314, PMID:24648495 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions EXP Thapsigargin affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]; Thapsigargin promotes the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]] CTD PMID:28347754 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Lamp5 lysosomal-associated membrane protein family, member 5 decreases expression ISO Thapsigargin results in decreased expression of LAMP5 mRNA CTD PMID:22378314 NCBI chr 3:129,012,677...129,031,522
Ensembl chr 3:129,018,592...129,031,521
JBrowse link
G Larp4 La ribonucleoprotein 4 increases expression ISO Thapsigargin results in increased expression of LARP4 protein CTD PMID:24648495 NCBI chr 7:141,630,229...141,676,242 JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator increases expression ISO Thapsigargin results in increased expression of LARP6 mRNA CTD PMID:22378314 NCBI chr 8:65,611,570...65,632,706
Ensembl chr 8:65,611,570...65,632,706
JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial decreases expression ISO Thapsigargin results in decreased expression of LARS2 mRNA CTD PMID:22378314 NCBI chr 8:132,441,277...132,537,176
Ensembl chr 8:132,441,285...132,536,369
JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO Thapsigargin results in increased expression of LBH mRNA CTD PMID:29453283 NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 decreases expression ISO Thapsigargin results in decreased expression of LCMT2 mRNA CTD PMID:22378314 NCBI chr 3:113,089,646...113,091,770
Ensembl chr 3:113,089,647...113,091,770
JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression
ISO Thapsigargin promotes the reaction [DDIT3 protein binds to LCN2 promoter]; Thapsigargin results in increased expression of and results in increased secretion of LCN2 protein
Thapsigargin results in increased expression of LCN2 mRNA
CTD PMID:22800509 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldlr low density lipoprotein receptor decreases expression
increases expression
ISO Thapsigargin results in decreased expression of LDLR mRNA
Thapsigargin results in increased expression of LDLR mRNA
CTD PMID:22378314, PMID:29453283 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component decreases expression ISO Thapsigargin results in decreased expression of LEO1 mRNA CTD PMID:22378314 NCBI chr 8:82,380,906...82,405,293
Ensembl chr 8:82,380,757...82,405,644
JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 decreases expression ISO Thapsigargin results in decreased expression of LETM1 mRNA CTD PMID:22378314 NCBI chr14:82,227,790...82,267,298
Ensembl chr14:82,227,708...82,267,350
JBrowse link
G Lgals1 galectin 1 decreases expression ISO Thapsigargin results in decreased expression of LGALS1 mRNA CTD PMID:22378314 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lhfpl2 LHFPL tetraspan subfamily member 2 decreases expression ISO Thapsigargin results in decreased expression of LHFPL2 mRNA CTD PMID:22378314 NCBI chr 2:23,705,491...23,852,021
Ensembl chr 2:23,770,721...23,852,021
JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 increases expression ISO Thapsigargin results in increased expression of LHFPL6 mRNA