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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects response to substance |
ISO |
ABCC1 gene SNP affects the susceptibility to nitazoxanide |
CTD |
PMID:25622337 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
nitazoxanide binds to and results in decreased activity of AR protein |
CTD |
PMID:25752796 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO |
nitazoxanide promotes the reaction [EIF2A protein results in increased expression of ATF4 protein] nitazoxanide results in increased expression of ATF4 protein |
CTD |
PMID:19664635 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Dock8 |
dedicator of cytokinesis 8 |
affects response to substance |
ISO |
DOCK8 gene SNP affects the susceptibility to nitazoxanide |
CTD |
PMID:25622337 |
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NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
multiple interactions increases phosphorylation |
ISO |
IFNA2 protein promotes the reaction [nitazoxanide results in increased phosphorylation of EIF2A protein]; nitazoxanide promotes the reaction [EIF2A protein results in increased expression of ATF4 protein]; nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of EIF2A protein] |
CTD |
PMID:19664635 |
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NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions |
ISO |
IFNA2 protein promotes the reaction [nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of and results in increased activity of EIF2AK2 protein]]; nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of and results in increased activity of EIF2AK2 protein]; nitazoxanide promotes the reaction [EIF2AK2 protein results in increased phosphorylation of EIF2A protein] |
CTD |
PMID:19664635 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
nitazoxanide results in increased activity of NR1I3 protein |
CTD |
PMID:30247703 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Slit3 |
slit guidance ligand 3 |
affects response to substance |
ISO |
SLIT3 gene SNP affects the susceptibility to nitazoxanide |
CTD |
PMID:25622337 |
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NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634
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G |
Susd6 |
sushi domain containing 6 |
affects response to substance |
ISO |
SUSD6 gene SNP affects the susceptibility to nitazoxanide |
CTD |
PMID:25622337 |
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NCBI chr 6:100,437,826...100,531,621
Ensembl chr 6:100,437,642...100,531,606
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