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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-acetyloxy-4-(trifluoromethyl)benzoic acid
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Accession:CHEBI:94721 term browser browse the term
Definition:A salicylate that has formula C10H7F3O4.
Synonyms:related_synonym: Formula=C10H7F3O4;   InChI=1S/C10H7F3O4/c1-5(14)17-8-4-6(10(11,12)13)2-3-7(8)9(15)16/h2-4H,1H3,(H,15,16);   InChIKey=RMWVZGDJPAKBDE-UHFFFAOYSA-N;   SMILES=CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(=O)O;   disgren
 xref: CAS:322-79-2;   Drug_Central:2744;   LINCS:LSM-5797
 xref_mesh: MESH:C016167



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2-acetyloxy-4-(trifluoromethyl)benzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
EXP triflusal results in increased expression of NFKBIA protein
triflusal promotes the reaction [RELA protein binds to NFKBIA protein]
CTD PMID:16421291 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP triflusal inhibits the reaction [Phenylephrine results in increased expression of NPPA protein] CTD PMID:16421291 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
triflusal inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 protein]
triflusal inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
CTD PMID:10101034 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP triflusal promotes the reaction [RELA protein binds to NFKBIA protein] CTD PMID:16421291 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          oxygen atom 19423
            oxygen molecular entity 19423
              organooxygen compound 18998
                salicylates 694
                  2-acetyloxy-4-(trifluoromethyl)benzoic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        aromatic carboxylic acid 11735
                                          benzoic acids 11709
                                            2-acetyloxy-4-(trifluoromethyl)benzoic acid 4
paths to the root