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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-acetyloxy-4-(trifluoromethyl)benzoic acid
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Accession:CHEBI:94721 term browser browse the term
Definition:A salicylate that has formula C10H7F3O4.
Synonyms:related_synonym: Formula=C10H7F3O4;   InChI=1S/C10H7F3O4/c1-5(14)17-8-4-6(10(11,12)13)2-3-7(8)9(15)16/h2-4H,1H3,(H,15,16);   InChIKey=RMWVZGDJPAKBDE-UHFFFAOYSA-N;   SMILES=CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(=O)O;   disgren
 xref: CAS:322-79-2;   Drug_Central:2744;   LINCS:LSM-5797
 xref_mesh: MESH:C016167


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2-acetyloxy-4-(trifluoromethyl)benzoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
EXP triflusal results in increased expression of NFKBIA protein
triflusal promotes the reaction [RELA protein binds to NFKBIA protein]
CTD PMID:16421291 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP triflusal inhibits the reaction [Phenylephrine results in increased expression of NPPA protein] CTD PMID:16421291 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
triflusal inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 protein]
triflusal inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
CTD PMID:10101034 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP triflusal promotes the reaction [RELA protein binds to NFKBIA protein] CTD PMID:16421291 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19841
      atom 19839
        nonmetal atom 19720
          oxygen atom 19387
            oxygen molecular entity 19387
              organooxygen compound 18846
                salicylates 689
                  2-acetyloxy-4-(trifluoromethyl)benzoic acid 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18113
                                        aromatic carboxylic acid 10912
                                          benzoic acids 10881
                                            2-acetyloxy-4-(trifluoromethyl)benzoic acid 4
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