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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide
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Accession:CHEBI:94513 term browser browse the term
Definition:A thiadiazole that has formula C5H8N4O3S2.
Synonyms:related_synonym: Formula=C5H8N4O3S2;   InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12);   InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N;   N-Methylacetazolamide;   SMILES=CC(=O)N=C1N(N=C(S1)S(=O)(=O)N)C;   metazolamide;   methenamide;   neptazane;   neptazaneat
 xref: CAS:554-57-4;   Drug_Central:1741;   LINCS:LSM-5311
 xref_mesh: MESH:D008704

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N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410 		JBrowse link
G Car1 carbonic anhydrase 1 multiple interactions ISO Methazolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity		 ISO Methazolamide binds to and results in decreased activity of CA2 protein
Methazolamide results in decreased activity of CA2 protein		 CTD PMID:16858005 PMID:17826101 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Clu clusterin affects expression ISO Methazolamide affects the expression of CLU protein CTD PMID:12388792 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Gal galanin and GMAP prepropeptide affects expression ISO Methazolamide affects the expression of GAL protein CTD PMID:12388792 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925 		JBrowse link
G Gap43 growth associated protein 43 affects expression ISO Methazolamide affects the expression of GAP43 protein CTD PMID:12388792 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914 		JBrowse link
G Ret ret proto-oncogene affects expression ISO Methazolamide affects the expression of RET protein CTD PMID:12388792 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    chemical entity 19883
      atom 19881
        nonmetal atom 19760
          sulfur atom 16325
            sulfur molecular entity 16325
              organosulfur compound 15254
                sulfonamide 3183
                  N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    p-block element atom 19771
                      chalcogen 19464
                        oxygen atom 19425
                          oxygen molecular entity 19425
                            hydroxides 19147
                              oxoacid 18286
                                chalcogen oxoacid 11505
                                  sulfur oxoacid 11109
                                    sulfonic acid 7352
                                      sulfonic acid derivative 7352
                                        sulfonamide 3183
                                          N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
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