|
G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
affects localization |
ISO |
tephrosin affects the localization of AIFM1 protein |
CTD |
PMID:20056314 |
|
NCBI chr X:132,528,107...132,567,237
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
ISO |
tephrosin inhibits the reaction [EGF protein affects the phosphorylation of AKT1 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of AKT1 protein] tephrosin results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:20056314 |
|
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Birc2 |
baculoviral IAP repeat-containing 2 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein] |
CTD |
PMID:18841906 |
|
NCBI chr 8:13,253,697...13,273,672
|
|
G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of BIRC3 protein] |
CTD |
PMID:18841906 |
|
NCBI chr 8:13,285,702...13,313,329
|
|
G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
tephrosin inhibits the reaction [EGF protein affects the phosphorylation of AKT1 protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of EGFR protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of ERBB2 protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of MAPK1 protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of MAPK3 protein] |
CTD |
PMID:20056314 |
|
NCBI chr 2:220,893,660...220,976,331
|
|
G |
Egfr |
epidermal growth factor receptor |
affects localization multiple interactions |
ISO |
tephrosin affects the localization of EGFR protein Chloroquine inhibits the reaction [tephrosin results in increased degradation of EGFR protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of EGFR protein]; tephrosin results in increased degradation of and results in decreased phosphorylation of EGFR protein |
CTD |
PMID:20056314 |
|
NCBI chr14:95,378,626...95,551,358
|
|
G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions affects localization |
ISO |
Chloroquine inhibits the reaction [tephrosin results in increased degradation of ERBB2 protein]; tephrosin inhibits the reaction [EGF protein affects the phosphorylation of ERBB2 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of ERBB2 protein]; tephrosin results in increased degradation of and results in decreased phosphorylation of ERBB2 protein tephrosin affects the localization of ERBB2 protein |
CTD |
PMID:20056314 |
|
NCBI chr10:83,907,491...83,931,365
|
|
G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of ERBB3 protein]; tephrosin results in increased degradation of and results in decreased phosphorylation of ERBB3 protein |
CTD |
PMID:20056314 |
|
NCBI chr 7:1,579,079...1,600,379
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
decreases phosphorylation multiple interactions |
ISO |
tephrosin results in decreased phosphorylation of MAPK1 protein tephrosin inhibits the reaction [EGF protein affects the phosphorylation of MAPK1 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of MAPK1 protein] |
CTD |
PMID:20056314 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases phosphorylation multiple interactions |
ISO |
tephrosin results in decreased phosphorylation of MAPK3 protein tephrosin inhibits the reaction [EGF protein affects the phosphorylation of MAPK3 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of MAPK3 protein] |
CTD |
PMID:20056314 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of MMP9 protein] |
CTD |
PMID:18841906 |
|
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of NOS2 protein] |
CTD |
PMID:18841906 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of AKT1 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of ERBB2 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of ERBB3 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of MAPK1 protein]; tephrosin inhibits the reaction [NRG1 protein affects the phosphorylation of MAPK3 protein] |
CTD |
PMID:20056314 |
|
NCBI chr16:65,954,084...67,007,484
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein] |
CTD |
PMID:18841906 |
|
NCBI chr13:64,714,063...64,722,320
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
tephrosin inhibits the reaction [TNF protein results in increased expression of BIRC2 protein]; tephrosin inhibits the reaction [TNF protein results in increased expression of BIRC3 protein]; tephrosin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; tephrosin inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; tephrosin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein] |
CTD |
PMID:18841906 |
|
NCBI chr20:3,626,685...3,629,303
|
|