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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tectochrysin
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Accession:CHEBI:9426 term browser browse the term
Definition:A monohydroxyflavone that is flavone substituted by a hydroxy group at position 4 and a methoxy group at position 7 respectively.
Synonyms:exact_synonym: 5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one
 related_synonym: 5-hydroxy-7-methoxyflavone;   Formula=C16H12O4;   InChI=1S/C16H12O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-9,17H,1H3;   InChIKey=IRZVHDLBAYNPCT-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(cc2=O)-c1ccccc1
 xref: CAS:520-28-5;   KEGG:C11621;   KNApSAcK:C00003795;   LIPID_MAPS_instance:LMPK12110190
 xref_mesh: MESH:C402729
 xref: PMID:23583435;   PMID:24727421;   PMID:25083589;   Reaxys:254083;   Wikipedia:Techtochrysin



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tectochrysin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases response to substance
decreases activity
ISO [tectochrysin results in decreased activity of ABCB1 protein] which results in decreased export of calcein AM; tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Docetaxel]; tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Paclitaxel]; tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
ABCB1 protein results in decreased susceptibility to tectochrysin
CTD PMID:37259354 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases activity ISO tectochrysin results in decreased activity of ABCG2 protein CTD PMID:15930306 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      application 19653
        pharmaceutical 19492
          drug 19492
            antineoplastic agent 17735
              tectochrysin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19730
                        carbon atom 19727
                          organic molecular entity 19727
                            organic molecule 19680
                              organic cyclic compound 19492
                                organic heterocyclic compound 18854
                                  oxacycle 17814
                                    benzopyran 11778
                                      1-benzopyran 11522
                                        flavonoid 6899
                                          anthoxanthin 4538
                                            flavones 4538
                                              methoxyflavone 477
                                                monomethoxyflavone 189
                                                  tectochrysin 2
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