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ONTOLOGY REPORT - ANNOTATIONS


Term:tazobactam
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Accession:CHEBI:9421 term browser browse the term
Definition:A member of the class of penicillanic acids that is sulbactam in which one of the exocyclic methyl hydrogens is replaced by a 1,2,3-triazol-1-yl group; used (in the form of its sodium salt) in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Synonyms:exact_synonym: (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[(1H-1,2,3-triazol-1-yl)methyl]-4lambda(6)-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
 related_synonym: (2S,3S,5S)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide;   Formula=C10H12N4O5S;   InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1;   InChIKey=LPQZKKCYTLCDGQ-WEDXCCLWSA-N;   SMILES=C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O;   tazobactamum
 alt_id: CHEBI:45973
 xref: CAS:89786-04-9;   DrugBank:DB01606;   Drug_Central:2572;   KEGG:C07771;   KEGG:D00660;   LINCS:LSM-5323
 xref_mesh: MESH:C043265
 xref: PDBeChem:TAZ;   PMID:25098503;   PMID:25512410;   PMID:25529765;   PMID:25609660;   PMID:25662788;   PMID:25670823;   Reaxys:4787944;   Wikipedia:Tazobactam
 cyclic_relationship: is_conjugate_acid_of CHEBI:85193


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  CHEBI ontology 0
    role 0
      biological role 0
        antimicrobial agent 0
          tazobactam 0
Path 2
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  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic group 0
                              organic divalent group 0
                                organodiyl group 0
                                  carbonyl group 0
                                    carbonyl compound 0
                                      carboxylic acid 0
                                        carboacyl group 0
                                          univalent carboacyl group 0
                                            carbamoyl group 0
                                              carboxamide 0
                                                lactam 0
                                                  beta-lactam 0
                                                    beta-lactam antibiotic 0
                                                      penams 0
                                                        penicillanic acids 0
                                                          sulbactam 0
                                                            tazobactam 0
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