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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:syringin
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Accession:CHEBI:9380 term browser browse the term
Definition:A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage.
Synonyms:exact_synonym: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside
 related_synonym: (E)-sinapyl alcohol 4-glucoside;   4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol;   4-[(1E)-3-hydroxy-1-propen-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside;   Eleutheroside B;   Formula=C17H24O9;   InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1;   InChIKey=QJVXKWHHAMZTBY-GCPOEHJPSA-N;   Ligustrin;   Lilacin;   MAGNOLENIN A;   Methoxyconiferine;   SMILES=COc1cc(cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)\\C=C\\CO;   Syrigin;   Syringenin;   Syringoside;   beta-Terpineol
 xref: CAS:118-34-3;   FooDB:FDB011657;   KEGG:C01533;   KNApSAcK:C00000010
 xref_mesh: MESH:C028305
 xref: MetaCyc:CPD-63;   PMID:23620140;   PMID:23666001;   PMID:23678812;   PMID:31661774;   PMID:33867336;   PMID:34658231;   PMID:35580997;   PMID:35598514;   PMID:35706960;   PMID:35794555;   PMID:36411652;   PMID:36840496;   PMID:37243678;   PMID:37278329;   PMID:37882327;   PMID:38212029;   PMID:38520788;   PMID:38611823;   Reaxys:97166;   Wikipedia:Syringin



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syringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO syringin results in increased expression of BAX protein CTD PMID:35580997 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO syringin results in decreased expression of BCL2 protein CTD PMID:35580997 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO syringin results in decreased expression of BIRC5 protein CTD PMID:35580997 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,572,080...103,582,155
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein] CTD PMID:33146439 NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO syringin results in increased expression of CCND1 protein CTD PMID:35580997 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cdh1 cadherin 1 increases expression ISO syringin results in increased expression of CDH1 protein CTD PMID:35580997 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565
JBrowse link
G Ifng interferon gamma multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein] CTD PMID:33146439 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Il13 interleukin 13 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:33146439 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483
JBrowse link
G Il4 interleukin 4 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:33146439 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il5 interleukin 5 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:33146439 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
JBrowse link
G Il6 interleukin 6 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein] CTD PMID:33146439 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein] CTD PMID:33146439 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:33146439 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases phosphorylation ISO syringin results in increased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein] CTD PMID:33146439 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein] CTD PMID:33146439 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 increases expression ISO syringin results in increased expression of TP53 protein CTD PMID:35580997 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link

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Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        anti-inflammatory agent 16834
          syringin 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbohydrates and carbohydrate derivatives 15487
                                    carbohydrate 15487
                                      monosaccharide 5123
                                        aldose 3497
                                          aldohexose 3156
                                            glucose 3109
                                              D-glucose 3107
                                                D-glucopyranose 1828
                                                  beta-D-glucose 1672
                                                    beta-D-glucoside 1479
                                                      syringin 20
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