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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:syringin
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Accession:CHEBI:9380 term browser browse the term
Definition:A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage.
Synonyms:exact_synonym: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside
 related_synonym: 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol;   Eleutheroside B;   Formula=C17H24O9;   InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1;   InChIKey=QJVXKWHHAMZTBY-GCPOEHJPSA-N;   Ligustrin;   Lilacin;   MAGNOLENIN A;   Methoxyconiferine;   SMILES=COc1cc(cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)\\C=C\\CO;   Syrigin;   Syringenin;   Syringoside;   beta-Terpineol
 xref: Beilstein:97166;   CAS:118-34-3;   CAS:138-87-4;   KEGG:C01533;   KEGG:C17517;   KNApSAcK:C00000010;   KNApSAcK:C00007328;   KNApSAcK:C00030167
 xref_mesh: MESH:C028305
 xref: MetaCyc:CPD-63;   PMID:23620140;   PMID:23666001;   PMID:23678812;   Reaxys:97166;   Wikipedia:Syringin



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syringin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO syringin results in increased expression of BAX protein CTD PMID:35580997 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO syringin results in decreased expression of BCL2 protein CTD PMID:35580997 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO syringin results in decreased expression of BIRC5 protein CTD PMID:35580997 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein] CTD PMID:33146439 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO syringin results in increased expression of CCND1 protein CTD PMID:35580997 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdh1 cadherin 1 increases expression ISO syringin results in increased expression of CDH1 protein CTD PMID:35580997 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ifng interferon gamma multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein] CTD PMID:33146439 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il13 interleukin 13 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:33146439 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il4 interleukin 4 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein] CTD PMID:33146439 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:33146439 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il6 interleukin 6 multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein] CTD PMID:33146439 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein] CTD PMID:33146439 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein] CTD PMID:33146439 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases phosphorylation ISO syringin results in increased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases phosphorylation ISO syringin results in decreased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein] CTD PMID:33146439 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO syringin results in decreased expression of SQSTM1 protein CTD PMID:35580997 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein] CTD PMID:33146439 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression ISO syringin results in increased expression of TP53 protein CTD PMID:35580997 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        epitope 7032
          beta-D-glucose 1659
            beta-D-glucoside 1465
              syringin 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19730
                        carbon atom 19727
                          organic molecular entity 19727
                            heteroorganic entity 19484
                              organochalcogen compound 19243
                                organooxygen compound 19158
                                  carbohydrates and carbohydrate derivatives 15276
                                    carbohydrate 15276
                                      monosaccharide 4800
                                        aldose 3216
                                          aldohexose 2867
                                            glucose 2823
                                              D-glucose 2821
                                                D-glucopyranose 1808
                                                  beta-D-glucose 1659
                                                    beta-D-glucoside 1465
                                                      syringin 20
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