CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: syringin
Accession: CHEBI:9380
browse the term
Definition: A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage.
Synonyms: exact_synonym: 4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphenyl beta-D-glucopyranoside
related_synonym: 4-O-(beta-D-glucosyl)-trans-4-sinapoyl alcohol; Eleutheroside B; Formula=C17H24O9; InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1; InChIKey=QJVXKWHHAMZTBY-GCPOEHJPSA-N; Ligustrin; Lilacin; MAGNOLENIN A; Methoxyconiferine; SMILES=COc1cc(cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)\\C=C\\CO; Syrigin; Syringenin; Syringoside; beta-Terpineol
xref: Beilstein:97166; CAS:118-34-3; CAS:138-87-4; KEGG:C01533; KEGG:C17517; KNApSAcK:C00000010; KNApSAcK:C00007328; KNApSAcK:C00030167
xref_mesh: MESH:C028305
xref: MetaCyc:CPD-63; PMID:23620140; PMID:23666001; PMID:23678812; Reaxys:97166; Wikipedia:Syringin
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Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
syringin results in increased expression of BAX protein
CTD
PMID:35580997
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
syringin results in decreased expression of BCL2 protein
CTD
PMID:35580997
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
syringin results in decreased expression of BIRC5 protein
CTD
PMID:35580997
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Ccl11
C-C motif chemokine ligand 11
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of CCL11 protein]
CTD
PMID:33146439
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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Ccnd1
cyclin D1
increases expression
ISO
syringin results in increased expression of CCND1 protein
CTD
PMID:35580997
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cdh1
cadherin 1
increases expression
ISO
syringin results in increased expression of CDH1 protein
CTD
PMID:35580997
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Ifng
interferon gamma
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IFNG protein]
CTD
PMID:33146439
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Il13
interleukin 13
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL13 protein]
CTD
PMID:33146439
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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Il4
interleukin 4
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL4 protein]
CTD
PMID:33146439
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il5
interleukin 5
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL5 protein]
CTD
PMID:33146439
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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Il6
interleukin 6
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of IL6 protein]
CTD
PMID:33146439
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Mpo
myeloperoxidase
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased activity of MPO protein]
CTD
PMID:33146439
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of NFKBIA protein]
CTD
PMID:33146439
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Ppara
peroxisome proliferator activated receptor alpha
increases phosphorylation
ISO
syringin results in increased phosphorylation of PPARA protein
CTD
PMID:23691032
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
decreases phosphorylation
ISO
syringin results in decreased phosphorylation of PRKAA1 protein
CTD
PMID:23691032
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
decreases phosphorylation
ISO
syringin results in decreased phosphorylation of PRKAA2 protein
CTD
PMID:23691032
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of and results in increased phosphorylation of RELA protein]
CTD
PMID:33146439
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Sqstm1
sequestosome 1
decreases expression
ISO
syringin results in decreased expression of SQSTM1 protein
CTD
PMID:35580997
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Tnf
tumor necrosis factor
multiple interactions
ISO
syringin inhibits the reaction [Ovalbumin results in increased expression of TNF protein]
CTD
PMID:33146439
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
increases expression
ISO
syringin results in increased expression of TP53 protein
CTD
PMID:35580997
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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