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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:9362 term browser browse the term
Definition:An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
Synonyms:exact_synonym: 2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
 related_synonym: (+-)-2-(p-(2-thenoyl)phenyl)propionic acid;   2-(4-(2-Thenoyl)phenyl)propionsaeure;   2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid;   4-(2-Thenoyl)hydratropsaeure;   Formula=C14H12O3S;   InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17);   InChIKey=MDKGKXOCJGEUJW-UHFFFAOYSA-N;   PROFENAL;   SMILES=CC(C(O)=O)c1ccc(cc1)C(=O)c1cccs1;   SUTOPROFEN;   alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid;   p-2-thenoylhydratropic acid;   suprofene;   suprofenum
 alt_id: CHEBI:193117
 xref: Beilstein:1430606;   CAS:40828-46-4;   DrugBank:DB00870;   Drug_Central:2546;   KEGG:C07320;   KEGG:D00452;   LINCS:LSM-4406
 xref_mesh: MESH:D013496
 xref: PMID:11195850;   PMID:11409928;   PMID:14570769;   PMID:14664336;   PMID:27559371;   PMID:7918773;   PMID:8058269;   Patent:DE2353357;   Patent:US4035376;   Reaxys:1430606;   Wikipedia:Suprofen

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suprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO Suprofen results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Suprofen results in increased expression of GCLC mRNA CTD PMID:11909699 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Suprofen results in increased expression of GCLM mRNA CTD PMID:11909699 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19823
    role 19773
      application 19486
        anti-inflammatory agent 15835
          anti-inflammatory drug 13630
            non-steroidal anti-inflammatory drug 12717
              suprofen 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19823
    subatomic particle 19821
      composite particle 19821
        hadron 19821
          baryon 19821
            nucleon 19821
              atomic nucleus 19821
                atom 19821
                  main group element atom 19720
                    p-block element atom 19720
                      carbon group element atom 19643
                        carbon atom 19633
                          organic molecular entity 19633
                            organic group 18739
                              organic divalent group 18730
                                organodiyl group 18730
                                  carbonyl group 18678
                                    carbonyl compound 18678
                                      carboxylic acid 18376
                                        monocarboxylic acid 17639
                                          suprofen 3
paths to the root