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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:9362 term browser browse the term
Definition:An aromatic ketone that is thiophene substituted at C-2 by a 4-(1-carboxyethyl)benzoyl group.
Synonyms:exact_synonym: 2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
 related_synonym: (+-)-2-(p-(2-thenoyl)phenyl)propionic acid;   2-(4-(2-Thenoyl)phenyl)propionsaeure;   2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid;   4-(2-Thenoyl)hydratropsaeure;   Formula=C14H12O3S;   InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17);   InChIKey=MDKGKXOCJGEUJW-UHFFFAOYSA-N;   PROFENAL;   SMILES=CC(C(O)=O)c1ccc(cc1)C(=O)c1cccs1;   SUTOPROFEN;   alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid;   p-2-thenoylhydratropic acid;   suprofene;   suprofenum
 alt_id: CHEBI:193117
 xref: Beilstein:1430606;   CAS:40828-46-4;   DrugBank:DB00870;   Drug_Central:2546;   KEGG:C07320;   KEGG:D00452;   LINCS:LSM-4406
 xref_mesh: MESH:D013496
 xref: PMID:11195850;   PMID:11409928;   PMID:14570769;   PMID:14664336;   PMID:27559371;   PMID:7918773;   PMID:8058269;   Patent:DE2353357;   Patent:US4035376;   Reaxys:1430606;   Wikipedia:Suprofen

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suprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhrs11 dehydrogenase/reductase 11 decreases activity ISO Suprofen results in decreased activity of DHRS11 protein CTD PMID:30926317 NCBI chr10:72,144,042...72,153,496
Ensembl chr10:72,144,042...72,153,375
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Suprofen results in increased expression of GCLC mRNA CTD PMID:11909699 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Suprofen results in increased expression of GCLM mRNA CTD PMID:11909699 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        anti-inflammatory agent 14948
          anti-inflammatory drug 13611
            non-steroidal anti-inflammatory drug 12694
              suprofen 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        monocarboxylic acid 17406
                                          suprofen 3
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