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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfamic acid
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Accession:CHEBI:9330 term browser browse the term
Definition:The simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms.
Synonyms:exact_synonym: amidohydroxidodioxidosulfur;   sulfuramidic acid
 related_synonym: Amidoschwefelsaeure;   Amidosulfuric acid;   Aminosulfonic acid;   Formula=H3NO3S;   Imidosulfonic acid;   InChI=1S/H3NO3S/c1-5(2,3)4/h(H3,1,2,3,4);   InChIKey=IIACRCGMVDHOTQ-UHFFFAOYSA-N;   SMILES=NS(O)(=O)=O;   Sulfamidic acid;   Sulfamidsaeure;   Sulfaminic acid;   [S(NH2)O2(OH)];   sulphamic acid;   sulphamidic acid
 xref: CAS:5329-14-6;   Gmelin:25628
 xref_mesh: MESH:C005741
 xref: Reaxys:3043314;   Wikipedia:Sulfamic_acid


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sulfamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca4 carbonic anhydrase 4 decreases activity ISO sulfamic acid results in decreased activity of CA4 protein CTD PMID:15664814 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Ca5a carbonic anhydrase 5A decreases activity ISO sulfamic acid results in decreased activity of CA5A protein CTD PMID:15664814 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca9 carbonic anhydrase 9 decreases activity ISO sulfamic acid results in decreased activity of CA9 protein CTD PMID:15664814 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO sulfamic acid results in decreased activity of CA1 protein CTD PMID:15664814 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO sulfamic acid results in decreased activity of CA2 protein CTD PMID:15664814 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Il18 interleukin 18 increases expression ISO sulfamic acid results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Sts steroid sulfatase decreases activity ISO sulfamic acid analog results in decreased activity of STS protein CTD PMID:15597397 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
bupirimate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO bupirimate results in increased activity of NR1I2 protein CTD PMID:16565514 PMID:21924250 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO bupirimate results in increased activity of NR1I3 protein CTD PMID:21924250 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
topiramate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
EXP Amino Acids, Peptides, and Proteins inhibits the reaction [topiramate results in increased expression of ABCB1 protein] CTD PMID:18473823 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression EXP topiramate results in increased expression of ABCC1 protein CTD PMID:18473823 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP topiramate results in increased expression of ABCC2 protein CTD PMID:18473823 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acadsb acyl-CoA dehydrogenase, short/branched chain increases expression EXP topiramate results in increased expression of ACADSB mRNA CTD PMID:16979414 NCBI chr 1:201,981,362...202,022,771
Ensembl chr 1:201,981,357...202,021,008
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression EXP topiramate results in decreased expression of ACSL4 mRNA CTD PMID:16979414 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
increases secretion
ISO topiramate results in increased expression of ADIPOQ mRNA
topiramate results in increased secretion of ADIPOQ protein
CTD PMID:12927809 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO topiramate results in increased expression of ADRA2A mRNA CTD PMID:22489711 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP topiramate results in increased expression of AGXT mRNA CTD PMID:16979414 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of AKT1 protein] CTD PMID:29753867 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Ass1 argininosuccinate synthase 1 decreases expression EXP topiramate results in decreased expression of ASS1 mRNA CTD PMID:16979414 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP topiramate results in decreased expression of AVPR1A mRNA CTD PMID:16979414 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in decreased expression of BDNF protein] CTD PMID:29753867 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Ca12 carbonic anhydrase 12 decreases activity ISO topiramate results in decreased activity of CA12 protein CTD PMID:21314129 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions ISO topiramate binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Topiramate inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Topiramate inhibits the reaction [Protons results in increased secretion of CALCA protein]; Topiramate inhibits the reaction [S-nitro-N-acetylpenicillamine results in increased secretion of CALCA protein] CTD PMID:16942474 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Capn6 calpain 6 increases expression EXP topiramate results in increased expression of CAPN6 mRNA CTD PMID:16979414 NCBI chr  X:115,049,113...115,073,824
Ensembl chr  X:115,049,154...115,073,890
JBrowse link
G Car1 carbonic anhydrase 1 multiple interactions ISO topiramate binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions
decreases activity
ISO topiramate binds to and results in decreased activity of CA2 protein
topiramate results in decreased activity of CA2 protein
CTD PMID:17826101 PMID:21314129 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 affects expression
multiple interactions
EXP topiramate affects the expression of CASP3 mRNA; topiramate affects the expression of CASP3 protein
topiramate inhibits the reaction [3-nitropropionic acid results in increased activity of CASP3 protein]
CTD PMID:19148780 PMID:29753867 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression EXP topiramate results in decreased expression of CEBPA mRNA CTD PMID:16979414 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Chka choline kinase alpha decreases expression EXP topiramate results in decreased expression of CHKA mRNA CTD PMID:16979414 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases expression EXP topiramate results in decreased expression of CHRNA7 mRNA CTD PMID:16979414 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP topiramate results in decreased expression of CITED2 mRNA CTD PMID:16979414 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cnr1 cannabinoid receptor 1 affects expression ISO topiramate affects the expression of CNR1 mRNA CTD PMID:22017514 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of CREB1 protein] CTD PMID:29753867 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity ISO topiramate results in decreased activity of CYP17A1 protein CTD PMID:15730543 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Drd2 dopamine receptor D2 increases expression ISO topiramate results in increased expression of DRD2 mRNA CTD PMID:22489711 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP topiramate results in increased expression of DUSP1 mRNA CTD PMID:16979414 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Fabp3 fatty acid binding protein 3 decreases expression EXP topiramate results in decreased expression of FABP3 mRNA CTD PMID:16979414 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions EXP topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides] CTD PMID:11123204 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions EXP topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides] CTD PMID:11123204 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions EXP topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides] CTD PMID:11123204 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions EXP topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides] CTD PMID:11123204 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions EXP topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]; topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides] CTD PMID:11123204 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Glul glutamate-ammonia ligase decreases activity ISO topiramate results in decreased activity of GLUL protein CTD PMID:10323596 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP topiramate results in decreased expression of GNAI2 mRNA CTD PMID:16979414 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression EXP topiramate results in increased expression of GOT2 mRNA CTD PMID:16979414 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP topiramate results in decreased expression of GPAM mRNA CTD PMID:16979414 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression EXP topiramate results in increased expression of GPD2 mRNA CTD PMID:16979414 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in decreased expression of GRIA2 mRNA] CTD PMID:29753867 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 affects response to substance ISO GRIK1 gene SNP affects the susceptibility to topiramate CTD PMID:19331489 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in decreased phosphorylation of GSK3B protein] CTD PMID:29753867 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 increases expression EXP topiramate results in increased expression of GTF2A2 mRNA CTD PMID:16979414 NCBI chr 8:76,422,341...76,435,587
Ensembl chr 8:76,422,359...76,435,473
JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP topiramate results in decreased expression of GYG1 mRNA CTD PMID:16979414 NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP topiramate results in increased expression of HMGCS1 mRNA CTD PMID:16979414 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases activity ISO topiramate results in decreased activity of HSD3B2 protein CTD PMID:15730543 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP topiramate results in increased expression of IDI1 mRNA CTD PMID:16979414 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase multiple interactions EXP [topiramate co-treated with Trinitrobenzenesulfonic Acid] results in decreased expression of IFI30 mRNA CTD PMID:21849664 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP topiramate results in decreased expression of IGF1 mRNA CTD PMID:16979414 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression EXP topiramate results in increased expression of ITPR1 mRNA CTD PMID:16979414 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO topiramate results in decreased activity of KCNH2 protein CTD PMID:15716081 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO topiramate affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Me1 malic enzyme 1 decreases expression EXP topiramate results in decreased expression of ME1 mRNA CTD PMID:16979414 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP topiramate results in increased expression of MVD mRNA CTD PMID:16979414 NCBI chr19:55,258,910...55,268,933
Ensembl chr19:55,258,905...55,268,951
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP topiramate results in increased expression of NOS2 protein CTD PMID:14511393 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy neuropeptide Y increases expression EXP topiramate results in increased expression of NPY protein CTD PMID:17572454 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO topiramate results in increased activity of NR1I2 protein CTD PMID:14636322 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 decreases expression EXP topiramate results in decreased expression of NR2F2 mRNA CTD PMID:16979414 NCBI chr 1:131,447,671...131,465,749
Ensembl chr 1:131,448,447...131,460,473
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP topiramate results in decreased expression of NR4A2 mRNA CTD PMID:16979414 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Pde4b phosphodiesterase 4B decreases expression EXP topiramate results in decreased expression of PDE4B mRNA CTD PMID:16979414 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression EXP topiramate results in decreased expression of PDK4 mRNA CTD PMID:16979414 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pick1 protein interacting with PRKCA 1 multiple interactions EXP topiramate inhibits the reaction [3-nitropropionic acid results in increased expression of PICK1 protein] CTD PMID:29753867 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840
JBrowse link
G Plcd4 phospholipase C, delta 4 decreases expression EXP topiramate results in decreased expression of PLCD4 mRNA CTD PMID:16979414 NCBI chr 9:81,816,395...81,844,364
Ensembl chr 9:81,816,872...81,844,364
JBrowse link
G Pld1 phospholipase D1 increases expression EXP topiramate results in increased expression of PLD1 mRNA CTD PMID:16979414 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit increases expression EXP topiramate results in increased expression of PPP5C mRNA CTD PMID:16979414 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 decreases expression EXP topiramate results in decreased expression of PRKAG1 mRNA CTD PMID:16979414 NCBI chr 7:140,489,499...140,506,925
Ensembl chr 7:140,489,492...140,546,908
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression EXP topiramate results in decreased expression of PRKAR2B mRNA CTD PMID:16979414 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO topiramate affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP topiramate results in decreased expression of SCD1 mRNA CTD PMID:16979414 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc16a1 solute carrier family 16 member 1 increases expression EXP topiramate results in increased expression of SLC16A1 mRNA CTD PMID:16979414 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc37a4 solute carrier family 37 member 4 decreases expression EXP topiramate results in decreased expression of SLC37A4 mRNA CTD PMID:16979414 NCBI chr 8:48,716,914...48,723,024
Ensembl chr 8:48,716,939...48,723,024
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO topiramate affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc6a6 solute carrier family 6 member 6 decreases expression EXP topiramate results in decreased expression of SLC6A6 mRNA CTD PMID:16979414 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression EXP topiramate results in decreased expression of SLC7A1 mRNA CTD PMID:16979414 NCBI chr12:8,032,775...8,108,972
Ensembl chr12:8,032,809...8,108,972
JBrowse link
G Sqle squalene epoxidase decreases expression EXP topiramate results in decreased expression of SQLE mRNA CTD PMID:16979414 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression EXP topiramate results in increased expression of SREBF1 mRNA CTD PMID:16979414 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Th tyrosine hydroxylase affects expression
increases expression
ISO topiramate affects the expression of TH mRNA
topiramate results in increased expression of TH mRNA
CTD PMID:22017514 PMID:22489711 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP topiramate inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of TRPV1 mRNA] CTD PMID:21849664 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Ucp3 uncoupling protein 3 decreases expression EXP topiramate results in decreased expression of UCP3 mRNA CTD PMID:16979414 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 affects response to substance ISO UGT2B7 gene SNP affects the susceptibility to topiramate CTD PMID:18686368 NCBI chr14:22,597,103...22,619,968 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          sulfur atom 16289
            sulfur molecular entity 16289
              sulfur oxoacid derivative 12279
                sulfonic acid derivative 7344
                  sulfamic acids 86
                    sulfamic acid 86
                      N-sulfoglucosamine + 0
                      N-sulfotyrosine 0
                      cyclohexylsulfamic acid 0
                      phaseolotoxin 0
                      sulfamate ester + 81
                      sulfamoyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      chalcogen 19391
                        oxygen atom 19353
                          oxygen molecular entity 19353
                            hydroxides 19103
                              oxoacid 18235
                                chalcogen oxoacid 11493
                                  sulfur oxoacid 11097
                                    sulfonic acid 7344
                                      sulfonic acid derivative 7344
                                        sulfamic acids 86
                                          sulfamic acid 86
                                            N-sulfoglucosamine + 0
                                            N-sulfotyrosine 0
                                            cyclohexylsulfamic acid 0
                                            phaseolotoxin 0
                                            sulfamate ester + 81
                                            sulfamoyl group 0
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