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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulbactam
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Accession:CHEBI:9321 term browser browse the term
Definition:A penicillanic acid that has formula C8H11NO5S.
Synonyms:exact_synonym: 2,2-dimethyl-1,1-dioxidopenam-3alpha-carboxylic acid
 related_synonym: (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide;   CP 45899;   CP45899;   Formula=C8H11NO5S;   InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1;   InChIKey=FKENQMMABCRJMK-RITPCOANSA-N;   SMILES=[H][C@@]12CC(=O)N1[C@@H](C(O)=O)C(C)(C)S2(=O)=O;   penicillanic acid 1,1-dioxide;   penicillanic acid sulfone;   sulbactamum
 xref: Beilstein:4192832;   CAS:68373-14-8;   CAS:69388-84-7;   Drug_Central:2492;   HMDB:HMDB0258566;   KEGG:C07770;   KEGG:D08533;   LINCS:LSM-5553
 xref_mesh: MESH:D013407
 xref: PDBeChem:0RN;   PMID:11220688;   PMID:17422866;   PMID:17422867;   PMID:17630699;   PMID:18611714;   PMID:22974281;   PMID:37603677;   PMID:37679343;   PMID:8557585;   PMID:8935129;   Patent:BE867859;   Patent:US4234579;   Wikipedia:Sulbactam
 cyclic_relationship: is_conjugate_acid_of CHEBI:229543



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sulbactam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 increases transport ISO ABCC4 protein results in increased transport of Sulbactam CTD PMID:17939016 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
tazobactam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of IL1B mRNA] CTD PMID:16369182 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of TNF mRNA] CTD PMID:16369182 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      chemical role 19524
        donor 18969
          Bronsted acid 18849
            oxoacid 18823
              carbon oxoacid 18695
                carboxylic acid 18692
                  penicillanic acids 315
                    sulbactam 3
                      sultamicillin + 0
                      tazobactam 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            heteroorganic entity 19558
                              organochalcogen compound 19317
                                organooxygen compound 19233
                                  carbon oxoacid 18695
                                    carboxylic acid 18692
                                      carboacyl group 17724
                                        univalent carboacyl group 17724
                                          carbamoyl group 17577
                                            carboxamide 17577
                                              lactam 8394
                                                beta-lactam 831
                                                  beta-lactam antibiotic 816
                                                    penams 315
                                                      penicillanic acids 315
                                                        sulbactam 3
                                                          sultamicillin + 0
                                                          tazobactam 2
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