CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: sulbactam
Accession: CHEBI:9321
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Definition: A penicillanic acid that has formula C8H11NO5S.
Synonyms: exact_synonym: 2,2-dimethyl-1,1-dioxidopenam-3alpha-carboxylic acid
related_synonym: (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 4,4-dioxide; CP 45899; CP45899; Formula=C8H11NO5S; InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1; InChIKey=FKENQMMABCRJMK-RITPCOANSA-N; SMILES=[H][C@@]12CC(=O)N1[C@@H](C(O)=O)C(C)(C)S2(=O)=O; penicillanic acid 1,1-dioxide; penicillanic acid sulfone; sulbactamum
xref: Beilstein:4192832; CAS:68373-14-8; CAS:69388-84-7; Drug_Central:2492; HMDB:HMDB0258566; KEGG:C07770; KEGG:D08533; LINCS:LSM-5553
xref_mesh: MESH:D013407
xref: PDBeChem:0RN; PMID:11220688; PMID:17422866; PMID:17422867; PMID:17630699; PMID:18611714; PMID:22974281; PMID:37603677; PMID:37679343; PMID:8557585; PMID:8935129; Patent:BE867859; Patent:US4234579; Wikipedia:Sulbactam
cyclic_relationship: is_conjugate_acid_of CHEBI:229543
G
Abcc4
ATP binding cassette subfamily C member 4
increases transport
ISO
ABCC4 protein results in increased transport of Sulbactam
CTD
PMID:17939016
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
G
Il1b
interleukin 1 beta
multiple interactions
EXP
Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of IL1B mRNA]
CTD
PMID:16369182
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Tnf
tumor necrosis factor
multiple interactions
EXP
Ozone promotes the reaction [[tazobactam co-treated with Piperacillin] results in increased expression of TNF mRNA]
CTD
PMID:16369182
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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