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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sufentanil
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Accession:CHEBI:9316 term browser browse the term
Definition:An anilide resulting from the formal condensation of the aryl amino group of 4-(methoxymethyl)-N-phenyl-1-[2-(2-thienyl)ethyl]piperidin-4-amine with propanoic acid.
Synonyms:exact_synonym: N-{4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
 related_synonym: Formula=C22H30N2O2S;   InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3;   InChIKey=GGCSSNBKKAUURC-UHFFFAOYSA-N;   N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide;   N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide;   SMILES=CCC(=O)N(c1ccccc1)C1(CCN(CCc2cccs2)CC1)COC;   Sufentanyl;   sufentanilum
 xref: CAS:56030-54-7;   DrugBank:DB00708;   Drug_Central:2491;   HMDB:HMDB0014846;   KEGG:C08022;   KEGG:D05938
 xref_mesh: MESH:D017409
 xref: PMID:10628901;   PMID:10945855;   PMID:11137863;   PMID:11504823;   PMID:15475572;   PMID:15828831;   PMID:16621415;   PMID:17118343;   PMID:9580589;   Patent:DE2610228;   Patent:US3998834;   Reaxys:499558;   Wikipedia:Sufentanil



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sufentanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr3a 5-hydroxytryptamine receptor 3A affects activity ISO Sufentanil affects the activity of HTR3A protein CTD PMID:18635474 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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G Pomc proopiomelanocortin decreases expression ISO Sufentanil results in decreased expression of POMC protein modified form CTD PMID:15714323 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        pharmacological role 19090
          analgesic 14629
            opioid analgesic 656
              sufentanil 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            inorganic hydride 17901
                              pnictogen hydride 17884
                                nitrogen hydride 17773
                                  azane 17503
                                    ammonia 17521
                                      organic amino compound 17521
                                        primary amino compound 8282
                                          primary amine 5868
                                            primary arylamine 3136
                                              aniline 2978
                                                anilide 499
                                                  sufentanil 2
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