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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:92842 term browser browse the term
Definition:A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
Synonyms:exact_synonym: 1,4-diazepane-1,4-diyldipropane-3,1-diyl bis(3,4,5-trimethoxybenzoate)
 related_synonym: Formula=C31H44N2O10;   InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3;   InChIKey=QVZCXCJXTMIDME-UHFFFAOYSA-N;   N,N'-bis[3-(3,4,5-trimethoxybenzoyloxy)propyl]homopiperazine;   SMILES=COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1;   dilazepum;   tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanediyl-3,4,5-trimethoxybenzoate
 xref: CAS:35898-87-4;   Chemspider:2965;   DrugBank:DB13715;   Drug_Central:893;   KEGG:D07843;   LINCS:LSM-3068
 xref_mesh: MESH:D004109
 xref: PDBeChem:8DZ;   PMID:12358150;   PMID:12627880;   PMID:12954370;   PMID:14551048;   PMID:15386824;   PMID:15456541;   PMID:18360052;   PMID:20424118;   PMID:20647687;   PMID:22562044;   PMID:23318848;   PMID:25091947;   PMID:31235912;   PMID:6136584;   PMID:7630041;   PMID:8531061;   PMID:9824428;   Wikipedia:Dilazep
 cyclic_relationship: is_conjugate_base_of CHEBI:170000

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dilazep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Dilazep results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO Dilazep inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:9396714 PMID:11085929 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        pharmaceutical 19624
          drug 19655
            cardiovascular drug 7726
              vasodilator agent 5846
                dilazep 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        aromatic carboxylic acid 11811
                                          benzoic acids 11786
                                            benzoate ester 5092
                                              dilazep 2
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