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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:92842 term browser browse the term
Definition:A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.
Synonyms:exact_synonym: 1,4-diazepane-1,4-diyldipropane-3,1-diyl bis(3,4,5-trimethoxybenzoate)
 related_synonym: Formula=C31H44N2O10;   InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3;   InChIKey=QVZCXCJXTMIDME-UHFFFAOYSA-N;   N,N'-bis[3-(3,4,5-trimethoxybenzoyloxy)propyl]homopiperazine;   SMILES=COC1=CC(=CC(OC)=C1OC)C(=O)OCCCN1CCCN(CCCOC(=O)C2=CC(OC)=C(OC)C(OC)=C2)CC1;   dilazepum;   tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanediyl-3,4,5-trimethoxybenzoate
 xref: CAS:35898-87-4;   Chemspider:2965;   DrugBank:DB13715;   Drug_Central:893;   KEGG:D07843;   LINCS:LSM-3068
 xref_mesh: MESH:D004109
 xref: PDBeChem:8DZ;   PMID:12358150;   PMID:12627880;   PMID:12954370;   PMID:14551048;   PMID:15386824;   PMID:15456541;   PMID:18360052;   PMID:20424118;   PMID:20647687;   PMID:22562044;   PMID:23318848;   PMID:25091947;   PMID:31235912;   PMID:6136584;   PMID:7630041;   PMID:8531061;   PMID:9824428;   Wikipedia:Dilazep
 cyclic_relationship: is_conjugate_base_of CHEBI:170000

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dilazep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Dilazep results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO Dilazep inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301 PMID:9396714 PMID:11085929 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link

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  CHEBI ontology 19773
    role 19719
      application 19403
        pharmaceutical 19303
          drug 19303
            cardiovascular drug 7668
              vasodilator agent 5812
                dilazep 2
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  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic group 18613
                              organic divalent group 18604
                                organodiyl group 18604
                                  carbonyl group 18521
                                    carbonyl compound 18521
                                      carboxylic acid 18196
                                        aromatic carboxylic acid 11307
                                          benzoic acids 11278
                                            benzoate ester 5031
                                              dilazep 2
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