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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine
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Accession:CHEBI:92833 term browser browse the term
Definition:A N-arylpiperazine that has formula C16H18N4O2.
Synonyms:related_synonym: ET-495;   EU-4200;   Formula=C16H18N4O2;   InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2;   InChIKey=OQDPVLVUJFGPGQ-UHFFFAOYSA-N;   SMILES=C1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4;   piribedil HCl;   piribedil hydrochloride;   piribedil maleate;   piribedil methanesulfonate;   trivastal;   trivastan
 xref: CAS:3605-01-4;   Drug_Central:2202;   LINCS:LSM-3057
 xref_mesh: MESH:D010891


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2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 multiple interactions EXP
ISO
Piribedil binds to and results in increased activity of DRD2 protein CTD PMID:10728880 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO Piribedil binds to and results in increased activity of DRD3 protein CTD PMID:10728880 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      application 19477
        refrigerant 17487
          ammonia 17014
            organic amino compound 17013
              aromatic amine 13674
                N-arylpiperazine 2747
                  2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    main group molecular entity 19744
                      s-block molecular entity 19491
                        hydrogen molecular entity 19483
                          hydrides 18748
                            inorganic hydride 17481
                              pnictogen hydride 17454
                                nitrogen hydride 17296
                                  azane 17015
                                    ammonia 17014
                                      organic amino compound 17013
                                        tertiary amino compound 8653
                                          N-arylpiperazine 2747
                                            2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]pyrimidine 2
paths to the root