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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:stanozolol
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Accession:CHEBI:9249 term browser browse the term
Definition:An organic heteropentacyclic compound resulting from the formal condensation of the 3-keto-aldehyde moiety of oxymetholone with hydrazine. Like oxymetholone, it is a synthetic anabolic steroid. It has both anabolic and androgenic properties, and has been used to treat hereditary angioedema and various vascular disorders. It has also been widely abused by professional athletes.
Synonyms:exact_synonym: (1S,3aS,3bR,5aS,10aS,10bS,12aS)-1,10a,12a-trimethyl-1,2,3,3a,3b,4,5,5a,6,7,10,10a,10b,11,12,12a-hexadecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-ol
 related_synonym: Androstanazole;   Formula=C21H32N2O;   InChI=1S/C21H32N2O/c1-19-11-13-12-22-23-18(13)10-14(19)4-5-15-16(19)6-8-20(2)17(15)7-9-21(20,3)24/h12,14-17,24H,4-11H2,1-3H3,(H,22,23)/t14-,15+,16-,17-,19-,20-,21-/m0/s1;   InChIKey=LKAJKIOFIWVMDJ-IYRCEVNGSA-N;   SMILES=C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4Cc5[nH]ncc5C[C@]4(C)[C@H]3CC[C@]12C;   Stromba;   Strombaject;   Winstrol;   estanozolol;   stanozololum
 xref: CAS:10418-03-8;   DrugBank:DB06718;   Drug_Central:2477;   HMDB:HMDB0003116;   KEGG:C07311;   KEGG:D00444
 xref_mesh: MESH:D013197
 xref: PMID:20020362;   PMID:20209649;   PMID:20480277;   PMID:21496393;   PMID:21769864;   PMID:22197661;   PMID:22729959;   PMID:23374366;   PMID:23873860;   PMID:23978309;   PMID:24021270;   PMID:24405322;   Patent:US3030358;   Reaxys:8359772;   Wikipedia:Stanozolol


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stanozolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
increases activity
ISO 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-cumylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; bisphenol A inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; butylbenzyl phthalate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Chlordecone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Corticosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Coumestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Diethylstilbestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ethinyl Estradiol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; ethyl-p-hydroxybenzoate inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Flutamide metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Genistein inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Hexestrol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; hydroxyflutamide inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; kaempferol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Ketoconazole inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Linuron inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Methoxychlor inhibits the reaction [Stanozolol results in increased activity of AR protein]; Methoxychlor metabolite inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Spironolactone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; Stanozolol binds to and results in increased activity of AR protein; Testosterone inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; vinclozolin inhibits the reaction [Stanozolol results in increased activity of AR protein] CTD PMID:28009930, PMID:28377212, PMID:29162470 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Tert telomerase reverse transcriptase increases activity EXP Stanozolol results in increased activity of TERT protein CTD PMID:29717770 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        anti-anaemic agent 40
          oxymetholone 10
            stanozolol 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      ketone 16140
                                        oxo steroid 9275
                                          3-oxo steroid 8805
                                            3-oxo-5alpha-steroid 992
                                              oxymetholone 10
                                                stanozolol 2
paths to the root

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