Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:xylazine
go back to main search page
Accession:CHEBI:92386 term browser browse the term
Definition:A methyl benzene that is 1,3-dimethylbenzene which is substituted by a 5,6-dihydro-4H-1,3-thiazin-2-ylnitrilo group at position 2. It is an alpha2 adrenergic receptor agonist and frequently used in veterinary medicine as an emetic and sedative with analgesic and muscle relaxant properties.
Synonyms:exact_synonym: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
 related_synonym: 2-(2,6-dimethylanilino)-5,6-dihydro-4H-1,3-thiazine;   2-(2,6-dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazine;   5,6-dihydro-2-(2,6-xylidino)-4H-1,3-thiazine;   BAY 1470;   Chanazine;   Formula=C12H16N2S;   InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14);   InChIKey=BPICBUSOMSTKRF-UHFFFAOYSA-N;   N-(5,6-dihydro-4H-1,3-thiazinyl)-2,6-xylidine;   Rompun;   SMILES=C=1(C=CC=C(C1NC2=NCCCS2)C)C;   WH 7286;   xilazina;   xilazine;   xylazinum
 xref: CAS:7361-61-7;   DrugBank:DB11477;   KEGG:D08683;   LINCS:LSM-2477
 xref_mesh: MESH:D014991
 xref: PMID:27049320;   PMID:31652007;   PMID:31778611;   PMID:31863505;   PMID:31890977;   PMID:31945776;   PMID:31952632;   PMID:31965616;   PMID:31985287;   PMID:31992523;   PMID:32016857;   PMID:32048309;   PMID:32059754;   PMID:32119148;   PMID:32166760;   PMID:32278647;   PMID:32299311;   Wikipedia:Xylazine
 cyclic_relationship: is_conjugate_base_of CHEBI:149565


show annotations for term's descendants       view all columns           Sort by:
 
xylazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      biological role 19737
        pharmacological role 18817
          analgesic 13069
            xylazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    main group molecular entity 19674
                      s-block molecular entity 19416
                        hydrogen molecular entity 19407
                          hydrides 18389
                            organic hydride 17747
                              organic fundamental parent 17747
                                hydrocarbon 17255
                                  cyclic hydrocarbon 15317
                                    monocyclic hydrocarbon 5770
                                      annulene 5592
                                        aromatic annulene 5592
                                          benzene 5592
                                            alkylbenzene 3344
                                              methylbenzene 3206
                                                xylazine 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.