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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-chloro-6-(1-piperazinyl)pyrazine
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Accession:CHEBI:92360 term browser browse the term
Definition:A N-arylpiperazine that has formula C8H11ClN4.
Synonyms:related_synonym: Formula=C8H11ClN4;   InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2;   InChIKey=CJAWPFJGFFNXQI-UHFFFAOYSA-N;   SMILES=C1CN(CCN1)C2=CN=CC(=N2)Cl
 xref: LINCS:LSM-2443
 xref_mesh: MESH:C014896


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2-chloro-6-(1-piperazinyl)pyrazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions EXP
ISO
6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein
[6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine
CTD PMID:10541732 PMID:16521035 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
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Term paths to the root
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  CHEBI ontology 19812
    role 19761
      application 19471
        refrigerant 17691
          ammonia 17278
            organic amino compound 17278
              aromatic amine 13701
                N-arylpiperazine 2768
                  2-chloro-6-(1-piperazinyl)pyrazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        tertiary amino compound 8677
                                          N-arylpiperazine 2768
                                            2-chloro-6-(1-piperazinyl)pyrazine 1
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