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ONTOLOGY REPORT - ANNOTATIONS


Term:sirolimus
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Accession:CHEBI:9168 term browser browse the term
Definition:A macrolide isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent.
Synonyms:exact_synonym: (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
 related_synonym: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone;   Antibiotic AY 22989;   Formula=C51H79NO13;   InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33+,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1;   InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N;   Rapamune;   SMILES=[H][C@]1(CC[C@@H](O)[C@@H](C1)OC)C[C@@H](C)[C@]1([H])CC(=O)[C@H](C)\\C=C(C)\\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\\C=C\\C=C\\C=C(C)\\[C@H](C[C@]2([H])CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@@]2([H])C(=O)O1)OC;   rapamycin;   sirolimusum
 alt_id: CHEBI:45276;   CHEBI:67812
 xref: CAS:53123-88-9 "ChemIDplus";   CAS:53123-88-9 "KEGG COMPOUND";   DrugBank:DB00877;   Drug_Central:2446 "DrugCentral";   HMDB:HMDB0015015;   KEGG:C07909;   KEGG:D00753;   KNApSAcK:C00018055;   LIPID_MAPS_instance:LMPK06000003 "LIPID MAPS"
 xref_mesh: MESH:D020123
 xref: PDBeChem:RAP;   PMID:22960739 "Europe PMC";   PMID:22981852 "Europe PMC";   PMID:22984623 "Europe PMC";   Reaxys:5848501 "Reaxys";   Wikipedia:Rapamycin


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sirolimus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G A2m alpha-2-macroglobulin JBrowse link 6 121,636,165 121,679,238 RGD:6480464
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 JBrowse link 4 53,030,789 53,159,988 RGD:6480464
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 JBrowse link 19 43,782,308 43,838,332 RGD:6480464
G Abcc8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 JBrowse link 7 46,104,523 46,180,039 RGD:6480464
G Acadl acyl-Coenzyme A dehydrogenase, long-chain JBrowse link 1 66,830,839 66,863,309 RGD:6480464
G Acadm acyl-Coenzyme A dehydrogenase, medium chain JBrowse link 3 153,922,353 153,944,643 RGD:6480464
G Ace2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 JBrowse link X 164,139,342 164,188,418 RGD:6480464
G Acer2 alkaline ceramidase 2 JBrowse link 4 86,874,348 86,932,524 RGD:6480464
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:6480464
G Actb actin, beta JBrowse link 5 142,903,115 142,907,976 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 JBrowse link X 48,474,944 48,513,563 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Akt1s1 AKT1 substrate 1 (proline-rich) JBrowse link 7 44,848,961 44,855,421 RGD:6480464
G Akt2 thymoma viral proto-oncogene 2 JBrowse link 7 27,591,552 27,640,826 RGD:6480464
G Angptl6 angiopoietin-like 6 JBrowse link 9 20,873,808 20,879,822 RGD:6480464
G Aopep aminopeptidase O JBrowse link 13 62,964,893 63,326,096 RGD:6480464
G Apod apolipoprotein D JBrowse link 16 31,296,192 31,314,808 RGD:6480464
G App amyloid beta (A4) precursor protein JBrowse link 16 84,952,666 85,175,255 RGD:6480464
G Aqp2 aquaporin 2 JBrowse link 15 99,579,056 99,584,545 RGD:6480464
G Ar androgen receptor JBrowse link X 98,148,757 98,323,218 RGD:6480464
G Asns asparagine synthetase JBrowse link 6 7,675,165 7,693,209 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 1 191,170,296 191,183,333 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:6480464
G Atg4a autophagy related 4A, cysteine peptidase JBrowse link X 140,953,877 141,164,270 RGD:6480464
G Atg4b autophagy related 4B, cysteine peptidase JBrowse link 1 93,754,905 93,789,606 RGD:6480464
G Atg5 autophagy related 5 JBrowse link 10 44,268,322 44,364,299 RGD:6480464
G Aurkb aurora kinase B JBrowse link 11 69,045,624 69,051,664 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 19 6,941,861 6,951,905 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bbc3 BCL2 binding component 3 JBrowse link 7 16,308,398 16,318,334 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a JBrowse link 9 88,956,920 88,962,416 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:6480464
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:6480464
G Becn1 beclin 1, autophagy related JBrowse link 11 101,288,258 101,302,286 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 6 120,893,119 120,917,062 RGD:6480464
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 9 7,818,226 7,837,131 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 11 117,849,237 117,855,743 RGD:6480464
G Bnip3 BCL2/adenovirus E1B interacting protein 3 JBrowse link 7 138,890,836 138,909,506 RGD:6480464
G Btbd11 BTB (POZ) domain containing 11 JBrowse link 10 85,384,971 85,660,292 RGD:6480464
G Btc betacellulin, epidermal growth factor family member JBrowse link 5 91,357,261 91,402,994 RGD:6480464
G Btk Bruton agammaglobulinemia tyrosine kinase JBrowse link X 134,542,334 134,583,628 RGD:6480464
G Bub1 BUB1, mitotic checkpoint serine/threonine kinase JBrowse link 2 127,800,197 127,831,859 RGD:6480464
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase JBrowse link 2 118,598,202 118,641,592 RGD:6480464
G C1qa complement component 1, q subcomponent, alpha polypeptide JBrowse link 4 136,895,916 136,898,844 RGD:6480464
G C1qc complement component 1, q subcomponent, C chain JBrowse link 4 136,889,801 136,892,936 RGD:6480464
G C3 complement component 3 JBrowse link 17 57,203,967 57,228,136 RGD:6480464
G Cald1 caldesmon 1 JBrowse link 6 34,598,495 34,775,469 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 60,925,307 60,988,152 RGD:6480464
G Capn1 calpain 1 JBrowse link 19 5,988,545 6,015,825 RGD:6480464
G Casp1 caspase 1 JBrowse link 9 5,298,517 5,307,281 RGD:6480464
G Casp12 caspase 12 JBrowse link 9 5,345,442 5,373,034 RGD:6480464
G Casp2 caspase 2 JBrowse link 6 42,264,902 42,282,508 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp7 caspase 7 JBrowse link 19 56,396,833 56,442,348 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cav3 caveolin 3 JBrowse link 6 112,459,505 112,472,872 RGD:6480464
G Ccn2 cellular communication network factor 2 JBrowse link 10 24,595,442 24,598,683 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 9 70,407,689 70,421,554 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 6 127,125,162 127,152,188 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 17 47,505,051 47,599,689 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 4 11,190,433 11,204,779 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 5 93,267,573 93,276,231 RGD:6480464
G Ccni cyclin I JBrowse link 5 93,181,933 93,206,495 RGD:6480464
G Cd36 CD36 molecule JBrowse link 5 17,781,690 17,888,959 RGD:6480464
G Cd38 CD38 antigen JBrowse link 5 43,868,809 43,912,374 RGD:6480464
G Cd68 CD68 antigen JBrowse link 11 69,664,213 69,666,170 RGD:6480464
G Cd80 CD80 antigen JBrowse link 16 38,457,430 38,495,958 RGD:6480464
G Cd84 CD84 antigen JBrowse link 1 171,839,697 171,890,718 RGD:6480464
G Cd86 CD86 antigen JBrowse link 16 36,568,956 36,666,158 RGD:6480464
G Cdc20 cell division cycle 20 JBrowse link 4 118,432,901 118,437,343 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 8 106,603,350 106,670,247 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 16,588,877 16,809,246 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 10 69,335,146 69,352,912 RGD:6480464
G Cdk2 cyclin-dependent kinase 2 JBrowse link 10 128,697,938 128,705,051 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 10 127,063,535 127,067,288 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 6 134,920,401 134,925,525 RGD:6480464
G Cdx2 caudal type homeobox 2 JBrowse link 5 147,300,900 147,307,249 RGD:6480464
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha JBrowse link 7 35,119,293 35,121,928 RGD:6480464
G Cenpx centromere protein X JBrowse link 11 120,710,941 120,713,895 RGD:6480464
G Cfd complement factor D (adipsin) JBrowse link 10 79,890,853 79,892,655 RGD:6480464
G Chrnb3 cholinergic receptor, nicotinic, beta polypeptide 3 JBrowse link 8 27,368,711 27,399,730 RGD:6480464
G Cks1b CDC28 protein kinase 1b JBrowse link 3 89,415,472 89,418,291 RGD:6480464
G Cldn7 claudin 7 JBrowse link 11 69,964,779 69,967,886 RGD:6480464
G Clec4a1 C-type lectin domain family 4, member a1 JBrowse link 6 122,921,848 122,934,619 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Col1a2 collagen, type I, alpha 2 JBrowse link 6 4,505,618 4,541,543 RGD:6480464
G Cp ceruloplasmin JBrowse link 3 19,956,933 20,009,750 RGD:6480464
G Cpt1b carnitine palmitoyltransferase 1b, muscle JBrowse link 15 89,416,405 89,425,862 RGD:6480464
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 4 107,903,982 107,923,589 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 1 64,532,794 64,604,548 RGD:6480464
G Crebrf CREB3 regulatory factor JBrowse link 17 26,715,594 26,776,637 RGD:6480464
G Crtc2 CREB regulated transcription coactivator 2 JBrowse link 3 90,253,858 90,264,125 RGD:6480464
G Cse1l chromosome segregation 1-like (S. cerevisiae) JBrowse link 2 166,906,041 166,946,389 RGD:6480464
G Csf1 colony stimulating factor 1 (macrophage) JBrowse link 3 107,741,048 107,760,469 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) JBrowse link 11 54,247,270 54,249,899 RGD:6480464
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:6480464
G Ctsk cathepsin K JBrowse link 3 95,499,210 95,509,387 RGD:6480464
G Cxcl10 chemokine (C-X-C motif) ligand 10 JBrowse link 5 92,346,638 92,348,889 RGD:6480464
G Cxcl13 chemokine (C-X-C motif) ligand 13 JBrowse link 5 95,956,939 95,961,068 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cyba cytochrome b-245, alpha polypeptide JBrowse link 8 122,424,771 122,432,940 RGD:6480464
G Cybb cytochrome b-245, beta polypeptide JBrowse link X 9,435,252 9,487,766 RGD:6480464
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 1 74,713,148 74,737,897 RGD:6480464
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 JBrowse link 7 26,307,192 26,315,088 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Ddit4l DNA-damage-inducible transcript 4-like JBrowse link 3 137,623,672 137,628,332 RGD:6480464
G Deptor DEP domain containing MTOR-interacting protein JBrowse link 15 55,112,317 55,259,273 RGD:6480464
G Diablo diablo, IAP-binding mitochondrial protein JBrowse link 5 123,511,330 123,524,164 RGD:6480464
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 JBrowse link 4 101,496,648 101,642,799 RGD:6480464
G Dnmt1 DNA methyltransferase (cytosine-5) 1 JBrowse link 9 20,907,206 20,959,888 RGD:6480464
G Dpyd dihydropyrimidine dehydrogenase JBrowse link 3 118,562,109 119,432,924 RGD:6480464
G Dusp10 dual specificity phosphatase 10 JBrowse link 1 184,034,381 184,075,636 RGD:6480464
G Dusp15 dual specificity phosphatase-like 15 JBrowse link 2 152,940,995 152,952,400 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 2 154,559,400 154,569,892 RGD:6480464
G E2f4 E2F transcription factor 4 JBrowse link 8 105,297,663 105,305,370 RGD:6480464
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:6480464
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 10 81,176,631 81,182,509 RGD:6480464
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha JBrowse link 12 78,862,072 78,887,010 RGD:6480464
G Eif4b eukaryotic translation initiation factor 4B JBrowse link 15 102,073,773 102,097,173 RGD:6480464
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 3 138,526,191 138,559,696 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 27,260,327 27,275,656 RGD:6480464
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 JBrowse link 16 20,672,720 20,692,883 RGD:6480464
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 JBrowse link 7 111,067,985 111,083,030 RGD:6480464
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 JBrowse link 11 106,397,620 106,487,796 RGD:6480464
G Ero1l ERO1-like (S. cerevisiae) JBrowse link 14 45,283,087 45,318,572 RGD:6480464
G Espl1 extra spindle pole bodies 1, separase JBrowse link 15 102,296,254 102,324,357 RGD:6480464
G Esr1 estrogen receptor 1 (alpha) JBrowse link 10 4,611,989 5,005,633 RGD:6480464
G Evi2a ecotropic viral integration site 2a JBrowse link 11 79,526,560 79,530,609 RGD:6480464
G Ewsr1 Ewing sarcoma breakpoint region 1 JBrowse link 11 5,069,687 5,099,107 RGD:6480464
G F2 coagulation factor II JBrowse link 2 91,612,397 91,636,457 RGD:6480464
G F3 coagulation factor III JBrowse link 3 121,723,537 121,735,052 RGD:6480464
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fbln1 fibulin 1 JBrowse link 15 85,205,949 85,286,294 RGD:6480464
G Fbxo32 F-box protein 32 JBrowse link 15 58,175,879 58,214,892 RGD:6480464
G Fbxo5 F-box protein 5 JBrowse link 10 5,799,158 5,805,465 RGD:6480464
G Fcgr1 Fc receptor, IgG, high affinity I JBrowse link 3 96,282,909 96,293,969 RGD:6480464
G Fgb fibrinogen beta chain JBrowse link 3 83,042,246 83,049,863 RGD:6480464
G Fgf1 fibroblast growth factor 1 JBrowse link 18 38,838,672 38,929,470 RGD:6480464
G Fgf7 fibroblast growth factor 7 JBrowse link 2 126,034,658 126,091,185 RGD:6480464
G Fkbp1a FK506 binding protein 1a JBrowse link 2 151,542,483 151,561,691 RGD:6480464
G Flt3l FMS-like tyrosine kinase 3 ligand JBrowse link 7 45,131,183 45,136,490 RGD:6480464
G Folr1 folate receptor 1 (adult) JBrowse link 7 101,858,331 101,870,788 RGD:6480464
G Foxm1 forkhead box M1 JBrowse link 6 128,362,994 128,375,886 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 3 52,268,337 52,350,109 RGD:6480464
G Foxo3 forkhead box O3 JBrowse link 10 42,181,845 42,276,839 RGD:6480464
G Foxp1 forkhead box P1 JBrowse link 6 98,925,342 99,522,746 RGD:6480464
G Foxp3 forkhead box P3 JBrowse link X 7,579,676 7,595,243 RGD:6480464
G Frat1 frequently rearranged in advanced T cell lymphomas JBrowse link 19 41,829,970 41,832,583 RGD:6480464
G Fshb follicle stimulating hormone beta JBrowse link 2 107,055,986 107,059,651 RGD:6480464
G Ftl1 ferritin light polypeptide 1 JBrowse link 7 45,457,944 45,459,886 RGD:6480464
G Gabarap gamma-aminobutyric acid receptor associated protein JBrowse link 11 69,991,370 69,994,949 RGD:6480464
G Gabarapl1 gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 JBrowse link 6 129,533,192 129,542,331 RGD:6480464
G Gcm2 glial cells missing homolog 2 JBrowse link 13 41,101,427 41,111,035 RGD:6480464
G Gem GTP binding protein (gene overexpressed in skeletal muscle) JBrowse link 4 11,704,447 11,714,993 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 10 75,561,076 75,586,193 RGD:6480464
G Glb1 galactosidase, beta 1 JBrowse link 9 114,401,078 114,474,379 RGD:6480464
G Gm12248 predicted gene 12248 JBrowse link 11 58,063,682 58,093,196 RGD:6480464
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 5 139,423,150 139,427,800 RGD:6480464
G Gpnmb glycoprotein (transmembrane) nmb JBrowse link 6 49,036,518 49,058,182 RGD:6480464
G Gpr18 G protein-coupled receptor 18 JBrowse link 14 121,911,434 121,915,888 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:6480464
G Gstt1 glutathione S-transferase, theta 1 JBrowse link 10 75,783,813 75,798,584 RGD:6480464
G Gtpbp4 GTP binding protein 4 JBrowse link 13 8,972,070 8,996,116 RGD:6480464
G Guca2a guanylate cyclase activator 2a (guanylin) JBrowse link 4 119,637,732 119,639,465 RGD:6480464
G Gzmb granzyme B JBrowse link 14 56,258,836 56,262,334 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 9 44,334,715 44,336,077 RGD:6480464
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link 11 46,739,822 46,779,578 RGD:6480464
G Hbp1 high mobility group box transcription factor 1 JBrowse link 12 31,926,452 31,950,530 RGD:6480464
G Hes1 hes family bHLH transcription factor 1 JBrowse link 16 30,065,357 30,067,796 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 5 149,046,702 149,053,057 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase JBrowse link 13 96,648,962 96,670,936 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hnrnpd heterogeneous nuclear ribonucleoprotein D JBrowse link 5 99,955,935 99,979,130 RGD:6480464
G Hoxa9 homeobox A9 JBrowse link 6 52,223,097 52,227,370 RGD:6480464
G Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:6480464
G Hspa1b heat shock protein 1B JBrowse link 17 34,956,429 34,959,238 RGD:6480464
G Hspa5 heat shock protein 5 JBrowse link 2 34,772,090 34,776,529 RGD:6480464
G Hspb8 heat shock protein 8 JBrowse link 5 116,408,491 116,422,864 RGD:6480464
G Ibsp integrin binding sialoprotein JBrowse link 5 104,299,287 104,311,472 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 9 21,015,940 21,028,814 RGD:6480464
G Id1 inhibitor of DNA binding 1, HLH protein JBrowse link 2 152,736,251 152,737,410 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:6480464
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 11 7,197,787 7,202,546 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 11 7,206,086 7,215,498 RGD:6480464
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 1 72,858,065 72,874,865 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il12a interleukin 12a JBrowse link 3 68,690,644 68,698,550 RGD:6480464
G Il12b interleukin 12b JBrowse link 11 44,400,063 44,414,677 RGD:6480464
G Il17rb interleukin 17 receptor B JBrowse link 14 29,996,168 30,008,896 RGD:6480464
G Il18 interleukin 18 JBrowse link 9 50,554,700 50,581,841 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il2 interleukin 2 JBrowse link 3 37,120,713 37,125,954 RGD:6480464
G Il2ra interleukin 2 receptor, alpha chain JBrowse link 2 11,642,792 11,693,194 RGD:6480464
G Il2rg interleukin 2 receptor, gamma chain JBrowse link X 101,264,385 101,268,255 RGD:6480464
G Il3 interleukin 3 JBrowse link 11 54,265,085 54,267,279 RGD:6480464
G Il4 interleukin 4 JBrowse link 11 53,612,460 53,618,665 RGD:6480464
G Il4ra interleukin 4 receptor, alpha JBrowse link 7 125,552,271 125,579,474 RGD:6480464
G Il5 interleukin 5 JBrowse link 11 53,720,794 53,725,103 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Ing4 inhibitor of growth family, member 4 JBrowse link 6 125,039,848 125,049,265 RGD:6480464
G Ins1 insulin I JBrowse link 19 52,264,297 52,265,015 RGD:6480464
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 5 28,071,412 28,078,662 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 1 82,233,105 82,291,439 RGD:6480464
G Itgam integrin alpha M JBrowse link 7 128,062,640 128,118,491 RGD:6480464
G Itgav integrin alpha V JBrowse link 2 83,722,303 83,806,917 RGD:6480464
G Jag1 jagged 1 JBrowse link 2 137,081,451 137,116,520 RGD:6480464
G Jmy junction-mediating and regulatory protein JBrowse link 13 93,430,097 93,499,808 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Kifap3 kinesin-associated protein 3 JBrowse link 1 163,762,138 163,917,107 RGD:6480464
G Kifc5b kinesin family member C5B JBrowse link 17 26,917,091 26,932,579 RGD:6480464
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:6480464
G Kitl kit ligand JBrowse link 10 100,015,615 100,100,416 RGD:6480464
G Klf2 Kruppel-like factor 2 (lung) JBrowse link 8 72,319,062 72,321,654 RGD:6480464
G Klf5 Kruppel-like factor 5 JBrowse link 14 99,298,691 99,313,412 RGD:6480464
G Klf6 Kruppel-like factor 6 JBrowse link 13 5,861,489 5,870,393 RGD:6480464
G Klhl24 kelch-like 24 JBrowse link 16 20,097,553 20,129,226 RGD:6480464
G L1cam L1 cell adhesion molecule JBrowse link X 73,853,780 73,880,838 RGD:6480464
G Lamc2 laminin, gamma 2 JBrowse link 1 153,122,756 153,186,447 RGD:6480464
G Larp1 La ribonucleoprotein domain family, member 1 JBrowse link 11 57,973,418 58,062,034 RGD:6480464
G Lcn2 lipocalin 2 JBrowse link 2 32,384,637 32,387,739 RGD:6480464
G Lipe lipase, hormone sensitive JBrowse link 7 25,379,527 25,398,486 RGD:6480464
G Mad2l1 MAD2 mitotic arrest deficient-like 1 JBrowse link 6 66,535,221 66,541,107 RGD:6480464
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 2 155,276,364 155,278,073 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 8 121,590,438 121,598,760 RGD:6480464
G Map2k1 mitogen-activated protein kinase kinase 1 JBrowse link 9 64,185,769 64,253,605 RGD:6480464
G Map2k2 mitogen-activated protein kinase kinase 2 JBrowse link 10 81,105,913 81,124,697 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 14 33,377,898 33,447,353 RGD:6480464
G Mbnl2 muscleblind like splicing factor 2 JBrowse link 14 120,275,652 120,431,698 RGD:6480464
G Mbp myelin basic protein JBrowse link 18 82,475,091 82,585,637 RGD:6480464
G Mcl1 myeloid cell leukemia sequence 1 JBrowse link 3 95,656,944 95,663,179 RGD:6480464
G Mcm2 minichromosome maintenance complex component 2 JBrowse link 6 88,883,474 88,898,780 RGD:6480464
G Mcm7 minichromosome maintenance complex component 7 JBrowse link 5 138,164,583 138,172,111 RGD:6480464
G Mdm2 transformed mouse 3T3 cell double minute 2 JBrowse link 10 117,688,875 117,710,758 RGD:6480464
G Mir122 microRNA 122 JBrowse link 18 65,248,861 65,248,926 RGD:6480464
G Mir132 microRNA 132 JBrowse link 11 75,173,682 75,173,747 RGD:6480464
G Mir146 microRNA 146 JBrowse link 11 43,374,397 43,374,461 RGD:6480464
G Mir151 microRNA 151 JBrowse link 15 73,254,815 73,254,882 RGD:6480464
G Mir181a-2 microRNA 181a-2 JBrowse link 2 38,852,735 38,852,810 RGD:6480464
G Mir190a microRNA 190a JBrowse link 9 67,236,660 67,236,726 RGD:6480464
G Mir212 microRNA 212 JBrowse link 11 75,173,388 75,173,478 RGD:6480464
G Mir29c microRNA 29c JBrowse link 1 195,037,547 195,037,634 RGD:6480464
G Mir324 microRNA 324 JBrowse link 11 70,012,043 70,012,131 RGD:6480464
G Mir330 microRNA 330 JBrowse link 7 19,181,465 19,181,562 RGD:6480464
G Mir379 microRNA 379 JBrowse link 12 109,709,060 109,709,125 RGD:6480464
G Mir433 microRNA 433 JBrowse link 12 109,591,715 109,591,838 RGD:6480464
G Mir503 microRNA 503 JBrowse link X 53,053,984 53,054,054 RGD:6480464
G Mir654 microRNA 654 JBrowse link 12 109,723,218 109,723,301 RGD:6480464
G Mir758 microRNA 758 JBrowse link 12 109,712,810 109,712,890 RGD:6480464
G Mir760 microRNA 760 JBrowse link 3 122,293,585 122,293,703 RGD:6480464
G Mki67 antigen identified by monoclonal antibody Ki 67 JBrowse link 7 135,689,784 135,716,450 RGD:6480464
G Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) JBrowse link 17 24,473,550 24,479,114 RGD:6480464
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) JBrowse link 9 7,464,141 7,476,869 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mpz myelin protein zero JBrowse link 1 171,150,713 171,161,130 RGD:6480464
G Msr1 macrophage scavenger receptor 1 JBrowse link 8 39,543,232 39,642,750 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Mturn maturin, neural progenitor differentiation regulator homolog (Xenopus) JBrowse link 6 54,681,624 54,703,855 RGD:6480464
G Mybl2 myeloblastosis oncogene-like 2 JBrowse link 2 163,054,327 163,084,688 RGD:6480464
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6480464
G Myh11 myosin, heavy polypeptide 11, smooth muscle JBrowse link 16 14,194,527 14,292,188 RGD:6480464
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta JBrowse link 14 54,970,684 54,994,626 RGD:6480464
G Mylk myosin, light polypeptide kinase JBrowse link 16 34,745,199 35,002,436 RGD:6480464
G Myof myoferlin JBrowse link 19 37,899,036 38,043,577 RGD:6480464
G Naip2 NLR family, apoptosis inhibitory protein 2 JBrowse link 13 100,144,063 100,202,122 RGD:6480464
G Nanog Nanog homeobox JBrowse link 6 122,707,489 122,714,633 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 5 134,220,053 134,229,628 RGD:6480464
G Ncf2 neutrophil cytosolic factor 2 JBrowse link 1 152,800,153 152,836,990 RGD:6480464
G Ncf4 neutrophil cytosolic factor 4 JBrowse link 15 78,244,164 78,262,582 RGD:6480464
G Ndc80 NDC80 kinetochore complex component JBrowse link 17 71,496,100 71,526,857 RGD:6480464
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 JBrowse link 1 191,821,449 191,833,049 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 11 59,541,569 59,566,955 RGD:6480464
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 JBrowse link 11 93,958,925 93,968,521 RGD:6480464
G Nmu neuromedin U JBrowse link 5 76,333,495 76,363,777 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Nos3 nitric oxide synthase 3, endothelial cell JBrowse link 5 24,364,816 24,384,474 RGD:6480464
G Nphs2 nephrosis 2, podocin JBrowse link 1 156,310,535 156,328,035 RGD:6480464
G Nppa natriuretic peptide type A JBrowse link 4 148,000,722 148,002,074 RGD:6480464
G Nppb natriuretic peptide type B JBrowse link 4 147,985,786 147,987,205 RGD:6480464
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 2 91,184,061 91,202,829 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 39,410,545 39,519,421 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 2 38,692,656 38,714,542 RGD:6480464
G Nxt1 NTF2-related export protein 1 JBrowse link 2 148,672,615 148,676,026 RGD:6480464
G Ogn osteoglycin JBrowse link 13 49,608,015 49,624,501 RGD:6480464
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 JBrowse link 6 129,479,150 129,507,350 RGD:6480464
G Oxa1l oxidase assembly 1-like JBrowse link 14 54,360,841 54,369,669 RGD:6480464
G Pabpc1 poly(A) binding protein, cytoplasmic 1 JBrowse link 15 36,595,658 36,609,581 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pax8 paired box 8 JBrowse link 2 24,420,551 24,475,599 RGD:6480464
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic JBrowse link 2 173,153,073 173,159,274 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 2 132,249,286 132,253,180 RGD:6480464
G Pdcd4 programmed cell death 4 JBrowse link 19 53,892,231 53,937,592 RGD:6480464
G Pdgfb platelet derived growth factor, B polypeptide JBrowse link 15 79,995,865 80,024,614 RGD:6480464
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha JBrowse link 3 32,397,059 32,468,486 RGD:6480464
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 13 101,680,761 101,768,217 RGD:6480464
G Pim1 proviral integration site 1 JBrowse link 17 29,490,785 29,496,111 RGD:6480464
G Pkm pyruvate kinase, muscle JBrowse link 9 59,656,368 59,679,375 RGD:6480464
G Pkp4 plakophilin 4 JBrowse link 2 59,160,850 59,355,205 RGD:6480464
G Plcl1 phospholipase C-like 1 JBrowse link 1 55,405,946 55,754,285 RGD:6480464
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 66,458,604 66,465,558 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 9 58,217,179 58,249,796 RGD:6480464
G Pmp22 peripheral myelin protein 22 JBrowse link 11 63,128,982 63,159,547 RGD:6480464
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 7 141,455,188 141,460,743 RGD:6480464
G Pnrc1 proline-rich nuclear receptor coactivator 1 JBrowse link 4 33,245,423 33,248,787 RGD:6480464
G Pold2 polymerase (DNA directed), delta 2, regulatory subunit JBrowse link 11 5,872,180 5,878,256 RGD:6480464
G Postn periostin, osteoblast specific factor JBrowse link 3 54,359,267 54,391,041 RGD:6480464
G Pou5f1 POU domain, class 5, transcription factor 1 JBrowse link 17 35,506,032 35,510,777 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 15 85,734,910 85,806,851 RGD:6480464
G Ppard peroxisome proliferator activator receptor delta JBrowse link 17 28,232,754 28,301,469 RGD:6480464
G Pparg peroxisome proliferator activated receptor gamma JBrowse link 6 115,360,879 115,490,404 RGD:6480464
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha JBrowse link 5 51,454,249 52,115,853 RGD:6480464
G Ppl periplakin JBrowse link 16 5,086,291 5,132,481 RGD:6480464
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B JBrowse link 11 98,348,406 98,357,796 RGD:6480464
G Ppp2r1b protein phosphatase 2, regulatory subunit A, beta JBrowse link 9 50,856,896 50,899,325 RGD:6480464
G Prcp prolylcarboxypeptidase (angiotensinase C) JBrowse link 7 92,875,253 92,934,581 RGD:6480464
G Prf1 perforin 1 (pore forming protein) JBrowse link 10 61,297,751 61,304,684 RGD:6480464
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit JBrowse link 15 5,143,861 5,181,899 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 11 107,933,387 108,343,888 RGD:6480464
G Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:6480464
G Prkcg protein kinase C, gamma JBrowse link 7 3,303,532 3,331,099 RGD:6480464
G Prkch protein kinase C, eta JBrowse link 12 73,584,796 73,778,185 RGD:6480464
G Prlr prolactin receptor JBrowse link 15 10,177,238 10,349,190 RGD:6480464
G Psma1 proteasome (prosome, macropain) subunit, alpha type 1 JBrowse link 7 114,264,550 114,276,116 RGD:6480464
G Psma4 proteasome (prosome, macropain) subunit, alpha type 4 JBrowse link 9 54,950,781 54,958,034 RGD:6480464
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 JBrowse link 11 80,428,615 80,473,248 RGD:6480464
G Pten phosphatase and tensin homolog JBrowse link 19 32,757,577 32,826,160 RGD:6480464
G Ptger1 prostaglandin E receptor 1 (subtype EP1) JBrowse link 8 83,666,644 83,672,756 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Ptk2 PTK2 protein tyrosine kinase 2 JBrowse link 15 73,205,102 73,423,820 RGD:6480464
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 JBrowse link 7 47,077,795 47,134,026 RGD:6480464
G Ptprc protein tyrosine phosphatase, receptor type, C JBrowse link 1 138,062,859 138,175,756 RGD:6480464
G Pttg1 pituitary tumor-transforming gene 1 JBrowse link 11 43,420,244 43,427,463 RGD:6480464
G Rac1 Rac family small GTPase 1 JBrowse link 5 143,505,481 143,528,031 RGD:6480464
G Rad51 RAD51 recombinase JBrowse link 2 119,112,814 119,136,073 RGD:6480464
G Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,192,858 73,325,951 RGD:6480464
G Rbl1 RB transcriptional corepressor like 1 JBrowse link 2 157,145,893 157,204,534 RGD:6480464
G Rbl2 RB transcriptional corepressor like 2 JBrowse link 8 91,070,057 91,123,844 RGD:6480464
G Rcan1 regulator of calcineurin 1 JBrowse link 16 92,391,951 92,466,169 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Ren1 renin 1 structural JBrowse link 1 133,350,674 133,360,320 RGD:6480464
G Rest RE1-silencing transcription factor JBrowse link 5 77,265,494 77,286,432 RGD:6480464
G Rictor RPTOR independent companion of MTOR, complex 2 JBrowse link 15 6,708,349 6,800,401 RGD:6480464
G Rpl32 ribosomal protein L32 JBrowse link 6 115,805,514 115,808,743 RGD:6480464
G Rps20 ribosomal protein S20 JBrowse link 4 3,831,584 3,835,655 RGD:6480464
G Rps27l ribosomal protein S27-like JBrowse link 9 66,944,624 66,949,522 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 4 86,854,099 86,857,367 RGD:6480464
G Rps6ka1 ribosomal protein S6 kinase polypeptide 1 JBrowse link 4 133,847,290 133,887,797 RGD:6480464
G Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 JBrowse link 17 7,088,971 7,303,315 RGD:6480464
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 JBrowse link X 159,255,665 159,368,244 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Rps6kb2 ribosomal protein S6 kinase, polypeptide 2 JBrowse link 19 4,156,792 4,163,383 RGD:6480464
G Rptor regulatory associated protein of MTOR, complex 1 JBrowse link 11 119,602,905 119,899,591 RGD:6480464
G Rrad Ras-related associated with diabetes JBrowse link 8 104,628,070 104,631,350 RGD:6480464
G Rtn4 reticulon 4 JBrowse link 11 29,692,898 29,744,414 RGD:6480464
G Rtn4r reticulon 4 receptor JBrowse link 16 18,127,642 18,152,408 RGD:6480464
G S100a4 S100 calcium binding protein A4 JBrowse link 3 90,603,770 90,606,045 RGD:6480464
G S100g S100 calcium binding protein G JBrowse link X 162,961,992 162,964,599 RGD:6480464
G S1pr1 sphingosine-1-phosphate receptor 1 JBrowse link 3 115,710,433 115,715,055 RGD:6480464
G Scarb2 scavenger receptor class B, member 2 JBrowse link 5 92,441,311 92,505,657 RGD:6480464
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 19 44,293,676 44,306,864 RGD:6480464
G Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A JBrowse link 5 13,124,822 13,603,485 RGD:6480464
G Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C JBrowse link 5 17,574,816 17,730,268 RGD:6480464
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N JBrowse link 12 104,406,646 104,414,334 RGD:6480464
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 JBrowse link 5 137,061,504 137,072,272 RGD:6480464
G Sesn2 sestrin 2 JBrowse link 4 132,492,804 132,510,456 RGD:6480464
G Shisa2 shisa family member 2 JBrowse link 14 59,625,281 59,631,660 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:6480464
G Sirt2 sirtuin 2 JBrowse link 7 28,766,752 28,788,665 RGD:6480464
G Skp2 S-phase kinase-associated protein 2 (p45) JBrowse link 15 9,111,982 9,155,425 RGD:6480464
G Slc12a1 solute carrier family 12, member 1 JBrowse link 2 125,152,510 125,230,002 RGD:6480464
G Slc12a3 solute carrier family 12, member 3 JBrowse link 8 94,329,109 94,366,222 RGD:6480464
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 JBrowse link 14 121,459,621 121,505,254 RGD:6480464
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 JBrowse link 3 104,638,664 104,658,462 RGD:6480464
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 JBrowse link 5 33,104,219 33,162,699 RGD:6480464
G Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 JBrowse link 3 14,480,697 14,505,819 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 6 141,805,438 141,856,284 RGD:6480464
G Smim14 small integral membrane protein 14 JBrowse link 5 65,446,844 65,537,225 RGD:6480464
G Snai1 snail family zinc finger 1 JBrowse link 2 167,538,195 167,542,814 RGD:6480464
G Sox2 SRY (sex determining region Y)-box 2 JBrowse link 3 34,649,995 34,652,461 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 5 104,435,111 104,441,053 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 11 50,200,152 50,210,820 RGD:6480464
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 11 60,199,084 60,224,186 RGD:6480464
G Srr serine racemase JBrowse link 11 74,904,027 74,927,533 RGD:6480464
G Stard10 START domain containing 10 JBrowse link 7 101,317,086 101,346,626 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 11 100,886,806 100,939,594 RGD:6480464
G Sts steroid sulfatase RGD:6480464
G Syt1 synaptotagmin I JBrowse link 10 108,497,650 109,010,980 RGD:6480464
G Taf12 TATA-box binding protein associated factor 12 JBrowse link 4 132,274,355 132,293,329 RGD:6480464
G Tal1 T cell acute lymphocytic leukemia 1 JBrowse link 4 115,056,426 115,071,755 RGD:6480464
G Tars threonyl-tRNA synthetase JBrowse link 15 11,383,663 11,399,658 RGD:6480464
G Tax1bp1 Tax1 (human T cell leukemia virus type I) binding protein 1 JBrowse link 6 52,713,692 52,766,780 RGD:6480464
G Tcf19 transcription factor 19 JBrowse link 17 35,512,730 35,516,837 RGD:6480464
G Tead1 TEA domain family member 1 JBrowse link 7 112,679,356 112,906,784 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 13 73,626,911 73,649,843 RGD:6480464
G Tfeb transcription factor EB JBrowse link 17 47,737,037 47,792,416 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Tgfbr3 transforming growth factor, beta receptor III JBrowse link 5 107,106,567 107,289,629 RGD:6480464
G Tgm2 transglutaminase 2, C polypeptide JBrowse link 2 158,116,405 158,146,392 RGD:6480464
G Timeless timeless circadian clock 1 JBrowse link 10 128,232,063 128,252,941 RGD:6480464
G Timp3 tissue inhibitor of metalloproteinase 3 JBrowse link 10 86,300,412 86,349,505 RGD:6480464
G Tmem14c transmembrane protein 14C JBrowse link 13 41,016,250 41,022,582 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 JBrowse link 14 78,277,446 78,308,043 RGD:6480464
G Tpp2 tripeptidyl peptidase II JBrowse link 1 43,933,970 44,003,000 RGD:6480464
G Trib3 tribbles pseudokinase 3 JBrowse link 2 152,337,425 152,344,060 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Trp63 transformation related protein 63 JBrowse link 16 25,683,763 25,892,088 RGD:6480464
G Trp73 transformation related protein 73 JBrowse link 4 154,056,249 154,139,875 RGD:6480464
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 JBrowse link 19 18,730,177 18,892,521 RGD:6480464
G Tsc1 TSC complex subunit 1 JBrowse link 2 28,640,993 28,691,172 RGD:6480464
G Tsc2 TSC complex subunit 2 JBrowse link 17 24,595,816 24,632,676 RGD:6480464
G Ttk Ttk protein kinase JBrowse link 9 83,834,651 83,872,390 RGD:6480464
G Tyms thymidylate synthase JBrowse link 5 30,038,546 30,073,645 RGD:6480464
G Ulk1 unc-51 like kinase 1 JBrowse link 5 110,784,489 110,810,120 RGD:6480464
G Uri1 URI1, prefoldin-like chaperone JBrowse link 7 37,959,992 38,023,564 RGD:6480464
G Vasn vasorin JBrowse link 16 4,639,945 4,651,166 RGD:6480464
G Vcan versican JBrowse link 13 89,655,309 89,743,027 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464
G Wt1 Wilms tumor 1 homolog JBrowse link 2 105,126,529 105,173,614 RGD:6480464
G Xbp1 X-box binding protein 1 JBrowse link 11 5,520,641 5,525,993 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 42,059,613 42,109,664 RGD:6480464
G Ypel1 yippee like 1 JBrowse link 16 17,070,139 17,087,048 RGD:6480464
G Zfp628 zinc finger protein 628 JBrowse link 7 4,915,181 4,922,003 RGD:6480464
G Zic2 zinc finger protein of the cerebellum 2 JBrowse link 14 122,475,384 122,480,328 RGD:6480464
G Znrd1 zinc ribbon domain containing 1 JBrowse link 17 36,954,358 36,958,525 RGD:6480464
G Zwint ZW10 interactor JBrowse link 10 72,654,846 72,674,964 RGD:6480464
everolimus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 JBrowse link 2 69,238,282 69,342,616 RGD:6480464
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B JBrowse link 5 8,798,147 8,866,314 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 6 58,584,491 58,692,451 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 11 117,849,237 117,855,743 RGD:6480464
G Brd4 bromodomain containing 4 JBrowse link 17 32,196,272 32,284,743 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 6 127,125,162 127,152,188 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 17 47,505,051 47,599,689 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 8 106,603,350 106,670,247 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 8 93,166,072 93,197,804 RGD:6480464
G Ces2h carboxylesterase 2H JBrowse link 8 105,000,830 105,020,410 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 3 138,526,191 138,559,696 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 27,260,327 27,275,656 RGD:6480464
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 JBrowse link 16 20,672,720 20,692,883 RGD:6480464
G F3 coagulation factor III JBrowse link 3 121,723,537 121,735,052 RGD:6480464
G Igf1r insulin-like growth factor I receptor JBrowse link 7 67,952,257 68,233,668 RGD:6480464
G Itgam integrin alpha M JBrowse link 7 128,062,640 128,118,491 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6480464
G Ngf nerve growth factor JBrowse link 3 102,469,919 102,521,013 RGD:6480464
G Nos3 nitric oxide synthase 3, endothelial cell JBrowse link 5 24,364,816 24,384,474 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 1 171,213,934 171,218,845 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Ptk2 PTK2 protein tyrosine kinase 2 JBrowse link 15 73,205,102 73,423,820 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 14 73,192,858 73,325,951 RGD:6480464
G Rhoa ras homolog family member A JBrowse link 9 108,306,160 108,337,943 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 4 86,854,099 86,857,367 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:6480464
G Src Rous sarcoma oncogene JBrowse link 2 157,423,906 157,471,838 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20752
    role 20730
      biological role 20729
        immunomodulator 12927
          immunosuppressive agent 12182
            sirolimus 462
              everolimus 38
              ridaforolimus 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20752
    subatomic particle 20745
      composite particle 20745
        hadron 20745
          baryon 20745
            nucleon 20745
              atomic nucleus 20745
                atom 20745
                  main group element atom 20665
                    p-block element atom 20665
                      carbon group element atom 20401
                        carbon atom 20377
                          organic molecular entity 20377
                            organic group 19045
                              organic divalent group 19034
                                organodiyl group 19034
                                  carbonyl group 19007
                                    carbonyl compound 19007
                                      carboxylic acid 18675
                                        carboacyl group 17280
                                          univalent carboacyl group 17280
                                            carbamoyl group 16931
                                              carboxamide 16931
                                                lactam 2847
                                                  sirolimus 462
                                                    everolimus 38
                                                    ridaforolimus 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.