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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:suloctidil
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Accession:CHEBI:91639 term browser browse the term
Definition:An aryl sulfide that is benzene substituted by 1-hydroxy-2-(octylamino)propyl and propan-2-ylsulfanediyl groups at positions 1 and 4, respectively.
Synonyms:exact_synonym: 2-(octylamino)-1-[4-(propan-2-ylsulfanyl)phenyl]propan-1-ol
 related_synonym: 1-(4-isopropylthiophenyl)-2-n-octylaminopropanol;   1-(4-isopropylthiophenyl)-2-octylaminopropanol;   2-(octylamino)-1-(4-propan-2-ylsulfanylphenyl)propan-1-ol;   2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol;   2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]propan-1-ol;   4-[(1-methylethyl)thio]-alpha-[1-(octylamino)ethyl]benzenemethanol;   Formula=C20H35NOS;   InChI=1S/C20H35NOS/c1-5-6-7-8-9-10-15-21-17(4)20(22)18-11-13-19(14-12-18)23-16(2)3/h11-14,16-17,20-22H,5-10,15H2,1-4H3;   InChIKey=BFCDFTHTSVTWOG-UHFFFAOYSA-N;   SMILES=OC(C1=CC=C(SC(C)C)C=C1)C(NCCCCCCCC)C;   suloctidil (unspecified isomer)
 xref: CAS:54063-56-8
 xref_mesh: MESH:D013468


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(+-)-suloctidil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 increases expression ISO Suloctidil results in increased expression of ATF3 mRNA CTD PMID:32661532 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Suloctidil results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Suloctidil results in increased expression of HMOX1 mRNA CTD PMID:32661532 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Mt2 metallothionein 2 increases expression ISO Suloctidil results in increased expression of MT2A mRNA CTD PMID:32661532 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO MTF1 protein affects the reaction [Suloctidil results in increased expression of MT1M mRNA] CTD PMID:32661532 NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        NMR chemical shift reference compound 18453
          ammonia 18261
            organic amino compound 18261
              amino alcohol 1084
                suloctidil 5
                  (1R,2S)-suloctidil + 5
                  (1S,2R)-suloctidil + 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    main group molecular entity 20781
                      s-block molecular entity 20574
                        hydrogen molecular entity 20558
                          hydrides 19693
                            inorganic hydride 18602
                              pnictogen hydride 18589
                                nitrogen hydride 18502
                                  azane 18262
                                    ammonia 18261
                                      organic amino compound 18261
                                        secondary amino compound 8181
                                          suloctidil 5
                                            (1R,2S)-suloctidil + 5
                                            (1S,2R)-suloctidil + 5
paths to the root