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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:o-aminoacetophenone
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Accession:CHEBI:91110 term browser browse the term
Definition:An aromatic ketone that is acetophenone in which one of the ortho hydrogens of the phenyl group has been replaced by an amino group.
Synonyms:exact_synonym: 1-(2-aminophenyl)ethanone
 related_synonym: 1-acetyl-2-aminobenzene;   2-acetylaniline;   2-acetylphenylamine;   2-aminoacetophenone;   5 kaal;   Formula=C8H9NO;   InChI=1S/C8H9NO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,9H2,1H3;   InChIKey=GTDQGKWDWVUKTI-UHFFFAOYSA-N;   SMILES=C=1C(=C(C=CC1)N)C(C)=O;   o-acetylaniline;   o-aminoacetylbenzene;   o-aminophenyl methyl ketone;   ortho-aminoacetophenone
 xref: CAS:551-93-9
 xref_mesh: MESH:C055495
 xref: PMID:110829;   PMID:11946045;   PMID:21054900;   PMID:25043228;   PMID:25047450;   PMID:25488497;   PMID:25614099;   PMID:26777086;   PMID:26804051;   PMID:26935176;   PMID:8920148;   Reaxys:386122


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o-aminoacetophenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2A19 cytochrome P450 family 2 subfamily A member 19 multiple interactions EXP 2-aminoacetophenone inhibits the reaction [[CYP2A19 protein results in increased hydroxylation of coumarin] which results in increased chemical synthesis of 7-hydroxycoumarin]; 2-aminoacetophenone inhibits the reaction [CYP2A19 protein results in increased hydroxylation of coumarin] CTD PMID:30599194 NCBI chr 6:49,056,579...49,064,111
Ensembl chr 6:49,056,578...49,064,107 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions EXP 2-aminoacetophenone inhibits the reaction [[CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]; 2-aminoacetophenone inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol] CTD PMID:30599194 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    role 5044
      biological role 5016
        biochemical role 4938
          metabolite 4926
            prokaryotic metabolite 375
              bacterial metabolite 368
                o-aminoacetophenone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 5052
    subatomic particle 5043
      composite particle 5043
        hadron 5071
          baryon 5043
            nucleon 5043
              atomic nucleus 5043
                atom 5043
                  main group element atom 5013
                    main group molecular entity 5012
                      s-block molecular entity 4970
                        hydrogen molecular entity 4964
                          hydrides 4544
                            inorganic hydride 403
                              pnictogen hydride 399
                                nitrogen hydride 399
                                  azane 391
                                    ammonia 391
                                      organic amino compound 284
                                        aromatic amine 36
                                          anilines 11
                                            substituted aniline 10
                                              o-aminoacetophenone 2
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