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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:senecionine
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Accession:CHEBI:9107 term browser browse the term
Definition:A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.
Synonyms:exact_synonym: 12-hydroxysenecionan-11,16-dione
 related_synonym: Formula=C18H25NO5;   InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4-/t11-,14-,15-,18-/m1/s1;   InChIKey=HKODIGSRFALUTA-JTLQZVBZSA-N;   SMILES=[H]\\C(C)=C1/C[C@@H](C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@]([H])(OC1=O)[C@@]23[H];   Senecionin;   aureine
 xref: Beilstein:8162955;   Beilstein:934445;   Beilstein:94450;   CAS:130-01-8;   KEGG:C06176;   KNApSAcK:C00002116
 xref_mesh: MESH:C009237
 xref: PMID:15202562;   PMID:17260281;   PMID:21710732;   Reaxys:94450
 cyclic_relationship: is_conjugate_base_of CHEBI:77617


show annotations for term's descendants           Sort by:
senecionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP-binding cassette, sub-family A member 3 decreases expression EXP senecionine results in decreased expression of ABCA3 protein CTD PMID:35357534 NCBI chr17:24,570,997...24,629,178
Ensembl chr17:24,570,924...24,629,175 		JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases expression ISO
EXP		 senecionine results in decreased expression of ABCB11 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases expression EXP senecionine results in decreased expression of ABCB1 mRNA CTD PMID:31606820 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression ISO senecionine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 decreases expression EXP senecionine results in decreased expression of ABCB4 mRNA CTD PMID:31606820 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases expression EXP senecionine results in increased expression of ABCC1 mRNA CTD PMID:31606820 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 decreases expression ISO
EXP		 senecionine results in decreased expression of ABCC2 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 increases expression
decreases expression		 ISO
EXP		 senecionine results in increased expression of ABCC3 mRNA
senecionine results in decreased expression of ABCC3 mRNA		 CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 decreases expression EXP senecionine results in decreased expression of ABCC4 mRNA CTD PMID:31606820 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 decreases expression ISO senecionine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726 		JBrowse link
G Abhd11 abhydrolase domain containing 11 increases expression EXP senecionine results in increased expression of ABHD11 protein CTD PMID:35357534 NCBI chr 5:135,038,006...135,041,029
Ensembl chr 5:135,038,006...135,041,029 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression EXP senecionine results in increased expression of ABTB2 protein CTD PMID:35357534 NCBI chr 2:103,396,655...103,548,768
Ensembl chr 2:103,396,655...103,548,768 		JBrowse link
G Acaa1a acetyl-Coenzyme A acyltransferase 1A increases expression EXP senecionine results in increased expression of ACAA1A protein CTD PMID:35357534 NCBI chr 9:119,170,113...119,179,361
Ensembl chr 9:119,168,742...119,179,365 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression EXP senecionine results in increased expression of ACAA1B protein CTD PMID:35357534 NCBI chr 9:118,977,111...118,986,149
Ensembl chr 9:118,977,091...118,986,161 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 increases expression EXP senecionine results in increased expression of ACOT13 protein CTD PMID:35357534 NCBI chr13:25,001,938...25,015,472
Ensembl chr13:25,001,931...25,015,523 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP senecionine results in increased expression of ACOT2 protein CTD PMID:35357534 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression EXP senecionine results in increased expression of ACOT3 protein CTD PMID:35357534 NCBI chr12:84,098,918...84,107,174
Ensembl chr12:84,098,918...84,107,176 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression EXP senecionine results in increased expression of ACOT4 protein CTD PMID:35357534 NCBI chr12:84,084,028...84,091,497
Ensembl chr12:84,085,153...84,095,375 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSL3 mRNA CTD PMID:26100227 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression EXP senecionine results in decreased expression of ACSL4 protein CTD PMID:35357534 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSM3 mRNA CTD PMID:26100227 NCBI chr 7:119,360,106...119,384,119
Ensembl chr 7:119,360,146...119,386,736 		JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 increases expression EXP senecionine results in increased expression of ACSS3 protein CTD PMID:35357534 NCBI chr10:106,769,375...106,959,622
Ensembl chr10:106,769,378...106,959,529 		JBrowse link
G Actg2 actin, gamma 2, smooth muscle, enteric decreases expression ISO senecionine results in decreased expression of ACTG2 mRNA CTD PMID:34185104 NCBI chr 6:83,489,891...83,513,233
Ensembl chr 6:83,489,887...83,513,247 		JBrowse link
G Adam8 a disintegrin and metallopeptidase domain 8 increases expression ISO senecionine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 7:139,558,845...139,573,016
Ensembl chr 7:139,558,845...139,572,475 		JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression EXP senecionine results in increased expression of ADH1 protein CTD PMID:35357534 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459 		JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO senecionine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 1:38,212,936...38,704,036
Ensembl chr 1:38,216,407...38,704,036 		JBrowse link
G Agxt alanine-glyoxylate aminotransferase decreases expression ISO senecionine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 1:93,062,962...93,073,143
Ensembl chr 1:93,062,962...93,073,143 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP senecionine results in decreased expression of AIF1 protein CTD PMID:35357534 NCBI chr17:35,389,967...35,394,977
Ensembl chr17:35,389,967...35,395,044 		JBrowse link
G Akap12 A kinase anchor protein 12 increases expression EXP senecionine results in increased expression of AKAP12 protein CTD PMID:35357534 NCBI chr10:4,216,329...4,309,471
Ensembl chr10:4,216,380...4,309,470 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 increases expression ISO senecionine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression EXP senecionine results in increased expression of ALDH1B1 protein CTD PMID:35357534 NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 increases expression ISO senecionine results in increased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr12:84,477,491...84,497,798
Ensembl chr12:84,477,491...84,497,778 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO senecionine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr10:21,253,199...21,272,477
Ensembl chr10:21,253,190...21,272,484 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 increases expression EXP senecionine results in increased expression of ANAPC2 protein CTD PMID:35357534 NCBI chr 2:25,162,469...25,175,928
Ensembl chr 2:25,162,490...25,175,927 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression ISO senecionine results in decreased expression of ANKRD1 mRNA CTD PMID:34185104 NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499 		JBrowse link
G Anxa1 annexin A1 increases expression EXP senecionine results in increased expression of ANXA1 protein CTD PMID:35357534 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Apcs amyloid P component, serum decreases expression EXP senecionine results in decreased expression of APCS protein CTD PMID:35357534 NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608 		JBrowse link
G Apob apolipoprotein B decreases expression EXP senecionine results in decreased expression of APOB protein CTD PMID:35357534 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835 		JBrowse link
G Apoc1 apolipoprotein C-I decreases expression EXP senecionine results in decreased expression of APOC1 protein CTD PMID:35357534 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585 		JBrowse link
G Apoh apolipoprotein H decreases expression EXP senecionine results in decreased expression of APOH protein CTD PMID:35357534 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222 		JBrowse link
G Apom apolipoprotein M decreases expression EXP senecionine results in decreased expression of APOM protein CTD PMID:35357534 NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026 		JBrowse link
G Aqp4 aquaporin 4 decreases expression EXP senecionine results in decreased expression of AQP4 protein CTD PMID:35357534 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039 		JBrowse link
G Aqp8 aquaporin 8 increases expression EXP senecionine results in increased expression of AQP8 protein CTD PMID:35357534 NCBI chr 7:123,061,517...123,067,226
Ensembl chr 7:123,061,514...123,067,227 		JBrowse link
G Areg amphiregulin increases expression ISO senecionine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291 		JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression ISO senecionine results in increased expression of ARHGAP11A mRNA CTD PMID:32419051 NCBI chr 2:113,661,837...113,679,006
Ensembl chr 2:113,661,837...113,679,006 		JBrowse link
G Arl6ip1 ADP-ribosylation factor-like 6 interacting protein 1 decreases expression EXP senecionine results in decreased expression of ARL6IP1 protein CTD PMID:35357534 NCBI chr 7:117,718,113...117,728,848
Ensembl chr 7:117,718,114...117,728,885 		JBrowse link
G Arl6ip4 ADP-ribosylation factor-like 6 interacting protein 4 decreases expression EXP senecionine results in decreased expression of ARL6IP4 protein CTD PMID:35357534 NCBI chr 5:124,254,171...124,256,258
Ensembl chr 5:124,254,152...124,256,259 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO senecionine results in increased expression of ATAD2 mRNA CTD PMID:32419051 NCBI chr15:57,957,440...57,998,516
Ensembl chr15:57,957,440...57,998,478 		JBrowse link
G Atf3 activating transcription factor 3 increases expression EXP senecionine results in increased expression of ATF3 protein CTD PMID:35357534 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236 		JBrowse link
G Atp13a2 ATPase type 13A2 decreases expression EXP senecionine results in decreased expression of ATP13A2 protein CTD PMID:35357534 NCBI chr 4:140,711,812...140,734,641
Ensembl chr 4:140,714,184...140,734,641 		JBrowse link
G Atp2a3 ATPase, Ca++ transporting, ubiquitous increases expression EXP senecionine results in increased expression of ATP2A3 protein CTD PMID:35357534 NCBI chr11:72,851,995...72,883,869
Ensembl chr11:72,851,995...72,883,870 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 decreases expression EXP senecionine results in decreased expression of ATP5IF1 protein CTD PMID:35357534 NCBI chr 4:132,257,870...132,262,746
Ensembl chr 4:132,257,866...132,260,970 		JBrowse link
G Atp6v1h ATPase, H+ transporting, lysosomal V1 subunit H increases expression EXP senecionine results in increased expression of ATP6V1H protein CTD PMID:35357534 NCBI chr 1:5,153,201...5,233,438
Ensembl chr 1:5,140,241...5,232,752 		JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 increases expression EXP senecionine results in increased expression of ATPAF2 protein CTD PMID:35357534 NCBI chr11:60,291,450...60,309,427
Ensembl chr11:60,291,452...60,309,283 		JBrowse link
G Axin2 axin 2 decreases expression EXP senecionine results in decreased expression of AXIN2 mRNA CTD PMID:31606820 NCBI chr11:108,808,687...108,841,609
Ensembl chr11:108,811,175...108,841,609 		JBrowse link
G B3galt1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 decreases expression EXP senecionine results in decreased expression of B3GALT1 protein CTD PMID:35357534 NCBI chr 2:67,395,528...67,953,226
Ensembl chr 2:67,396,215...67,953,033 		JBrowse link
G Baat bile acid-Coenzyme A: amino acid N-acyltransferase decreases expression ISO senecionine results in decreased expression of BAAT mRNA CTD PMID:24641316 PMID:26100227 NCBI chr 4:49,489,416...49,507,915
Ensembl chr 4:49,489,422...49,506,557 		JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO senecionine results in decreased expression of BCL2L1 protein CTD PMID:29458164 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl3 B cell leukemia/lymphoma 3 increases expression EXP senecionine results in increased expression of BCL3 protein CTD PMID:35357534 NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695 		JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 decreases expression EXP senecionine results in decreased expression of BNIP3 protein CTD PMID:35357534 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248 		JBrowse link
G Bod1l biorientation of chromosomes in cell division 1-like decreases expression EXP senecionine results in decreased expression of BOD1L protein CTD PMID:35357534 NCBI chr 5:41,944,881...42,001,695
Ensembl chr 5:41,944,881...42,001,658 		JBrowse link
G Bpgm 2,3-bisphosphoglycerate mutase increases expression EXP senecionine results in increased expression of BPGM protein CTD PMID:35357534 NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548 		JBrowse link
G Btc betacellulin, epidermal growth factor family member increases expression EXP senecionine results in increased expression of BTC protein CTD PMID:35357534 NCBI chr 5:91,505,120...91,550,853
Ensembl chr 5:91,505,120...91,550,853 		JBrowse link
G C3 complement component 3 decreases expression EXP senecionine results in decreased expression of C3 protein CTD PMID:35357534 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G C3ar1 complement component 3a receptor 1 increases expression ISO senecionine results in increased expression of C3AR1 mRNA CTD PMID:34185104 NCBI chr 6:122,824,099...122,833,116
Ensembl chr 6:122,824,097...122,833,120 		JBrowse link
G C4b complement C4B (Chido blood group) decreases expression EXP senecionine results in decreased expression of C4B protein CTD PMID:35357534 NCBI chr17:34,947,249...34,962,876
Ensembl chr17:34,947,354...34,962,856 		JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP senecionine results in increased expression of CAMP protein CTD PMID:35357534 NCBI chr 9:109,676,445...109,678,524
Ensembl chr 9:109,676,447...109,678,685 		JBrowse link
G Car1 carbonic anhydrase 1 increases expression EXP senecionine results in increased expression of CA1 protein CTD PMID:35357534 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP senecionine results in increased expression of CA2 protein CTD PMID:35357534 NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830 		JBrowse link
G Car5a carbonic anhydrase 5a, mitochondrial increases expression EXP senecionine results in increased expression of CA5A protein CTD PMID:35357534 NCBI chr 8:122,642,874...122,671,651
Ensembl chr 8:122,642,865...122,671,643 		JBrowse link
G Car5b carbonic anhydrase 5b, mitochondrial increases expression EXP senecionine results in increased expression of CA5B protein CTD PMID:35357534 NCBI chr  X:162,759,818...162,811,006
Ensembl chr  X:162,759,818...162,810,993 		JBrowse link
G Casp12 caspase 12 increases expression ISO senecionine results in increased expression of CASP12 mRNA CTD PMID:32419051 NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 increases activity ISO senecionine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cav1 caveolin 1, caveolae protein decreases expression EXP senecionine results in decreased expression of CAV1 protein CTD PMID:35357534 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451 		JBrowse link
G Cavin3 caveolae associated 3 decreases expression EXP senecionine results in decreased expression of CAVIN3 protein CTD PMID:35357534 NCBI chr 7:105,129,823...105,131,404
Ensembl chr 7:105,129,290...105,131,507 		JBrowse link
G Ccdc137 coiled-coil domain containing 137 decreases expression EXP senecionine results in decreased expression of CCDC137 protein CTD PMID:35357534 NCBI chr11:120,348,947...120,355,184
Ensembl chr11:120,348,941...120,355,184 		JBrowse link
G Ccna2 cyclin A2 increases expression ISO senecionine results in increased expression of CCNA2 mRNA CTD PMID:32419051 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccne2 cyclin E2 increases expression ISO senecionine results in increased expression of CCNE2 mRNA CTD PMID:32419051 NCBI chr 4:11,190,489...11,204,781
Ensembl chr 4:11,191,351...11,204,779 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO senecionine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138 		JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression EXP senecionine results in decreased expression of CCPG1 protein CTD PMID:35357534 NCBI chr 9:72,892,692...72,923,622
Ensembl chr 9:72,892,711...72,923,622 		JBrowse link
G Cd163 CD163 antigen decreases expression EXP senecionine results in decreased expression of CD163 protein CTD PMID:35357534 NCBI chr 6:124,281,596...124,307,488
Ensembl chr 6:124,281,615...124,307,486 		JBrowse link
G Cd177 CD177 antigen increases expression EXP senecionine results in increased expression of CD177 protein CTD PMID:35357534 NCBI chr 7:24,443,408...24,459,759
Ensembl chr 7:24,443,408...24,459,736 		JBrowse link
G Cd300lg CD300 molecule like family member G decreases expression EXP senecionine results in decreased expression of CD300LG protein CTD PMID:35357534 NCBI chr11:101,932,337...101,946,443
Ensembl chr11:101,932,335...101,946,446 		JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) increases expression EXP
ISO		 senecionine results in increased expression of CD47 mRNA; senecionine results in increased expression of CD47 protein CTD PMID:35357534 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 decreases expression EXP senecionine results in decreased expression of CDADC1 protein CTD PMID:35357534 NCBI chr14:59,796,837...59,835,433
Ensembl chr14:59,796,837...59,835,408 		JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 decreases expression EXP senecionine results in decreased expression of CDKAL1 protein CTD PMID:35357534 NCBI chr13:29,375,729...30,039,665
Ensembl chr13:29,375,729...30,039,657 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO
EXP		 senecionine results in increased expression of CDKN1A mRNA
senecionine results in increased expression of CDKN1A protein		 CTD PMID:32419051 PMID:35357534 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cel carboxyl ester lipase decreases expression EXP senecionine results in decreased expression of CEL protein CTD PMID:35357534 NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415 		JBrowse link
G Cenpq centromere protein Q increases expression ISO senecionine results in increased expression of CENPQ mRNA CTD PMID:32419051 NCBI chr17:41,231,700...41,247,637
Ensembl chr17:41,233,942...41,245,938 		JBrowse link
G Cenpw centromere protein W increases expression ISO senecionine results in increased expression of CENPW mRNA CTD PMID:32419051 NCBI chr10:30,072,005...30,076,599
Ensembl chr10:30,070,565...30,076,556 		JBrowse link
G Cep97 centrosomal protein 97 increases expression EXP senecionine results in increased expression of CEP97 protein CTD PMID:35357534 NCBI chr16:55,720,250...55,755,237
Ensembl chr16:55,720,251...55,755,218 		JBrowse link
G Ces1f carboxylesterase 1F increases expression EXP senecionine results in increased expression of CES1F protein CTD PMID:35357534 NCBI chr 8:93,982,864...94,006,394
Ensembl chr 8:93,982,864...94,006,375 		JBrowse link
G Cfh complement component factor h decreases expression EXP senecionine results in decreased expression of CFH protein CTD PMID:35357534 NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502 		JBrowse link
G Cgnl1 cingulin-like 1 decreases expression EXP senecionine results in decreased expression of CGNL1 protein CTD PMID:35357534 NCBI chr 9:71,533,789...71,716,582
Ensembl chr 9:71,533,791...71,678,884 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 increases expression EXP senecionine results in increased expression of CHAMP1 protein CTD PMID:35357534 NCBI chr 8:13,919,699...13,931,637
Ensembl chr 8:13,919,641...13,931,639 		JBrowse link
G Chil3 chitinase-like 3 increases expression EXP senecionine results in increased expression of CHIL3 protein CTD PMID:35357534 NCBI chr 3:106,054,870...106,074,852
Ensembl chr 3:106,054,870...106,074,880 		JBrowse link
G Chtop chromatin target of PRMT1 decreases expression EXP senecionine results in decreased expression of CHTOP protein CTD PMID:35357534 NCBI chr 3:90,405,846...90,417,400
Ensembl chr 3:90,406,263...90,416,805 		JBrowse link
G Cib1 calcium and integrin binding 1 increases expression EXP senecionine results in increased expression of CIB1 protein CTD PMID:35357534 NCBI chr 7:79,876,904...79,882,367
Ensembl chr 7:79,876,895...79,882,561 		JBrowse link
G Cir1 corepressor interacting with RBPJ, 1 decreases expression EXP senecionine results in decreased expression of CIR1 protein CTD PMID:35357534 NCBI chr 2:73,113,445...73,142,922
Ensembl chr 2:73,113,449...73,143,045 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO senecionine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr 8:22,658,168...22,675,835
Ensembl chr 8:22,658,176...22,675,835 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1, ubiquitous decreases expression EXP senecionine results in decreased expression of CKMT1 protein CTD PMID:35357534 NCBI chr 2:121,188,257...121,194,218
Ensembl chr 2:121,188,195...121,194,218 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression ISO senecionine results in decreased expression of CKMT2 mRNA CTD PMID:34185104 NCBI chr13:92,001,510...92,025,001
Ensembl chr13:92,001,506...92,025,004 		JBrowse link
G Clec3b C-type lectin domain family 3, member b decreases expression EXP senecionine results in decreased expression of CLEC3B protein CTD PMID:35357534 NCBI chr 9:122,980,011...122,986,497
Ensembl chr 9:122,980,011...122,986,497 		JBrowse link
G Clec4a1 C-type lectin domain family 4, member a1 increases expression ISO senecionine results in increased expression of CLEC4A1 mRNA CTD PMID:34185104 NCBI chr 6:122,898,807...122,911,578
Ensembl chr 6:122,898,807...122,911,578 		JBrowse link
G Clec4f C-type lectin domain family 4, member f decreases expression ISO
EXP		 senecionine results in decreased expression of CLEC4F mRNA
senecionine results in decreased expression of CLEC4F protein		 CTD PMID:32419051 PMID:35357534 NCBI chr 6:83,621,524...83,633,098
Ensembl chr 6:83,621,524...83,633,169 		JBrowse link
G Cnbp cellular nucleic acid binding protein decreases expression EXP senecionine results in decreased expression of CNBP protein CTD PMID:35357534 NCBI chr 6:87,819,597...87,828,088
Ensembl chr 6:87,819,597...87,828,088 		JBrowse link
G Cntrl centriolin decreases expression EXP senecionine results in decreased expression of CNTRL protein CTD PMID:35357534 NCBI chr 2:34,999,504...35,068,834
Ensembl chr 2:34,999,504...35,068,834 		JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 decreases expression EXP senecionine results in decreased expression of COL18A1 protein CTD PMID:35357534 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382 		JBrowse link
G Cops3 COP9 signalosome subunit 3 increases expression EXP senecionine results in increased expression of COPS3 protein CTD PMID:35357534 NCBI chr11:59,708,621...59,739,080
Ensembl chr11:59,708,621...59,730,664 		JBrowse link
G Coro1a coronin, actin binding protein 1A increases expression EXP senecionine results in increased expression of CORO1A protein CTD PMID:35357534 NCBI chr 7:126,298,946...126,303,925
Ensembl chr 7:126,298,945...126,306,959 		JBrowse link
G Cpa1 carboxypeptidase A1, pancreatic decreases expression EXP senecionine results in decreased expression of CPA1 protein CTD PMID:35357534 NCBI chr 6:30,639,217...30,645,360
Ensembl chr 6:30,639,217...30,645,362 		JBrowse link
G Cpb2 carboxypeptidase B2 decreases expression EXP senecionine results in decreased expression of CPB2 protein CTD PMID:35357534 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995 		JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 decreases expression EXP senecionine results in decreased expression of CRELD1 protein CTD PMID:35357534 NCBI chr 6:113,460,317...113,470,304
Ensembl chr 6:113,460,258...113,470,304 		JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 decreases expression EXP senecionine results in decreased expression of CRELD2 protein CTD PMID:35357534 NCBI chr15:88,703,849...88,710,884
Ensembl chr15:88,703,849...88,710,886 		JBrowse link
G Crip1 cysteine-rich protein 1 decreases expression EXP senecionine results in decreased expression of CRIP1 protein CTD PMID:35357534 NCBI chr12:113,115,632...113,117,499
Ensembl chr12:113,109,936...113,117,499 		JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression ISO senecionine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221 		JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 increases expression EXP senecionine results in increased expression of CTDNEP1 protein CTD PMID:35357534 NCBI chr11:69,871,994...69,881,427
Ensembl chr11:69,871,982...69,881,427 		JBrowse link
G Ctrl chymotrypsin-like decreases expression EXP senecionine results in decreased expression of CTRB1 protein CTD PMID:35357534 NCBI chr 8:106,658,626...106,660,494
Ensembl chr 8:106,658,635...106,660,494 		JBrowse link
G Ctsg cathepsin G increases expression EXP senecionine results in increased expression of CTSG protein CTD PMID:35357534 NCBI chr14:56,337,342...56,340,031
Ensembl chr14:56,337,338...56,340,031 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP senecionine results in decreased expression of CXCL12 protein CTD PMID:35357534 NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO senecionine results in increased expression of CXCR4 mRNA CTD PMID:35357534 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP11A1 mRNA CTD PMID:26100227 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1A1 mRNA CTD PMID:26100227 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression		 ISO
EXP		 senecionine results in increased expression of CYP1A2 mRNA
senecionine results in decreased expression of CYP1A2 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1B1 mRNA CTD PMID:26100227 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 increases expression EXP senecionine results in increased expression of CYP2A4 protein CTD PMID:35357534 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513 		JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases expression EXP senecionine results in increased expression of CYP2A5 protein CTD PMID:35357534 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression
affects expression		 ISO
EXP		 senecionine results in increased expression of CYP2B6 mRNA
senecionine affects the expression of CYP2B10 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b19 cytochrome P450, family 2, subfamily b, polypeptide 19 increases expression EXP senecionine results in increased expression of CYP2B19 protein CTD PMID:35357534 NCBI chr 7:26,456,567...26,472,055
Ensembl chr 7:26,456,567...26,472,055 		JBrowse link
G Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 decreases expression EXP senecionine results in decreased expression of CYP2C39 protein CTD PMID:35357534 NCBI chr19:39,335,790...39,558,012
Ensembl chr19:39,499,306...39,556,973 		JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression ISO senecionine results in decreased expression of CYP2C18 mRNA CTD PMID:26100227 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
decreases expression		 ISO
EXP		 senecionine results in increased expression of CYP2E1 mRNA
senecionine results in decreased expression of CYP2E1 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 decreases expression EXP senecionine results in decreased expression of CYP3A11 mRNA CTD PMID:31606820 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 increases expression
decreases expression		 ISO senecionine results in increased expression of CYP3A7 mRNA
senecionine results in decreased expression of CYP3A5 mRNA		 CTD PMID:26100227 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Cyp4f14 cytochrome P450, family 4, subfamily f, polypeptide 14 decreases expression ISO senecionine results in decreased expression of CYP4F12 mRNA CTD PMID:26100227 NCBI chr17:33,122,331...33,136,353
Ensembl chr17:33,124,044...33,136,316 		JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 decreases expression ISO
EXP		 senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633 		JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 decreases expression ISO senecionine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371 		JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression ISO senecionine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr12:12,312,136...12,430,966
Ensembl chr12:12,312,140...12,430,966 		JBrowse link
G Dbr1 debranching RNA lariats 1 increases expression EXP senecionine results in increased expression of DBR1 protein CTD PMID:35357534 NCBI chr 9:99,457,839...99,467,060
Ensembl chr 9:99,457,852...99,466,554 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression ISO senecionine results in increased expression of DDIAS mRNA CTD PMID:32419051 NCBI chr 7:92,506,734...92,523,455
Ensembl chr 7:92,506,733...92,523,455 		JBrowse link
G Dedd death effector domain-containing decreases expression EXP senecionine results in decreased expression of DEDD protein CTD PMID:35357534 NCBI chr 1:171,152,229...171,170,843
Ensembl chr 1:171,156,713...171,169,899 		JBrowse link
G Dguok deoxyguanosine kinase increases expression EXP senecionine results in increased expression of DGUOK protein CTD PMID:35357534 NCBI chr 6:83,457,199...83,483,887
Ensembl chr 6:83,457,199...83,483,951 		JBrowse link
G Dhrs2 dehydrogenase/reductase member 2 increases expression ISO senecionine results in increased expression of DHRS2 mRNA CTD PMID:26100227 NCBI chr14:55,459,464...55,478,897
Ensembl chr14:55,459,464...55,478,892 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO senecionine results in increased expression of DHRS9 mRNA CTD PMID:26100227 NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877 		JBrowse link
G Diaph3 diaphanous related formin 3 increases expression ISO senecionine results in increased expression of DIAPH3 mRNA CTD PMID:32419051 NCBI chr14:86,892,793...87,378,683
Ensembl chr14:86,892,803...87,378,671 		JBrowse link
G Dip2a disco interacting protein 2 homolog A decreases expression EXP senecionine results in decreased expression of DIP2A protein CTD PMID:35357534 NCBI chr10:76,098,581...76,181,194
Ensembl chr10:76,095,263...76,181,125 		JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO senecionine results in increased expression of DLGAP5 mRNA CTD PMID:32419051 NCBI chr14:47,625,238...47,655,657
Ensembl chr14:47,625,236...47,655,864 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 decreases expression EXP senecionine results in decreased expression of DMBT1 protein CTD PMID:35357534 NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression EXP senecionine results in increased expression of DNAJB9 protein CTD PMID:35357534 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109 		JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 decreases expression EXP senecionine results in decreased expression of DNAJC12 protein CTD PMID:35357534 NCBI chr10:63,218,222...63,244,619
Ensembl chr10:63,218,222...63,246,355 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression EXP senecionine results in decreased expression of DNAJC15 protein CTD PMID:35357534 NCBI chr14:78,063,657...78,112,357
Ensembl chr14:78,058,121...78,112,565 		JBrowse link
G Dph5 diphthamide biosynthesis 5 increases expression EXP senecionine results in increased expression of DPH5 protein CTD PMID:35357534 NCBI chr 3:115,681,785...115,728,010
Ensembl chr 3:115,681,486...115,728,010 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression ISO senecionine results in decreased expression of DPYD mRNA CTD PMID:26100227 NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase increases expression ISO senecionine results in increased expression of DTL mRNA CTD PMID:32419051 NCBI chr 1:191,269,468...191,307,656
Ensembl chr 1:191,269,468...191,307,656 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP senecionine results in increased expression of DUSP1 protein CTD PMID:35357534 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102 		JBrowse link
G Dynll2 dynein light chain LC8-type 2 decreases expression EXP senecionine results in decreased expression of DYNLL2 protein CTD PMID:35357534 NCBI chr11:87,870,351...87,892,746
Ensembl chr11:87,870,351...87,878,359 		JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO senecionine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:96,375,936...96,420,786
Ensembl chr  X:96,377,446...96,420,822 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP senecionine results in decreased expression of EGFR protein CTD PMID:35357534 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G decreases expression EXP senecionine results in decreased expression of EIF3G protein CTD PMID:35357534 NCBI chr 9:20,805,645...20,809,886
Ensembl chr 9:20,805,645...20,809,919 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression EXP senecionine results in decreased expression of EIF4B protein CTD PMID:35357534 NCBI chr15:101,982,208...102,005,608
Ensembl chr15:101,982,208...102,005,608 		JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression EXP senecionine results in decreased expression of ELF1 protein CTD PMID:35357534 NCBI chr14:79,718,619...79,819,916
Ensembl chr14:79,718,634...79,819,934 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 decreases expression EXP senecionine results in decreased expression of ELOVL1 protein CTD PMID:35357534 NCBI chr 4:118,285,321...118,290,150
Ensembl chr 4:118,285,290...118,290,150 		JBrowse link
G Emilin2 elastin microfibril interfacer 2 increases expression ISO senecionine results in increased expression of EMILIN2 mRNA CTD PMID:34185104 NCBI chr17:71,559,167...71,618,551
Ensembl chr17:71,559,167...71,618,973 		JBrowse link
G Eng endoglin decreases expression EXP senecionine results in decreased expression of ENG protein CTD PMID:35357534 NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681 		JBrowse link
G Eno3 enolase 3, beta muscle increases expression EXP senecionine results in increased expression of ENO3 protein CTD PMID:35357534 NCBI chr11:70,543,973...70,553,339
Ensembl chr11:70,548,028...70,553,339 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP senecionine results in increased expression of ENTPD5 protein CTD PMID:35357534 NCBI chr12:84,420,649...84,455,803
Ensembl chr12:84,420,631...84,455,803 		JBrowse link
G Epha2 Eph receptor A2 increases expression EXP senecionine results in increased expression of EPHA2 protein CTD PMID:35357534 NCBI chr 4:141,028,532...141,056,695
Ensembl chr 4:141,028,551...141,056,695 		JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic decreases expression ISO senecionine results in decreased expression of EPHX2 mRNA CTD PMID:26100227 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949 		JBrowse link
G Epm2a epilepsy, progressive myoclonic epilepsy, type 2 gene alpha increases expression EXP senecionine results in increased expression of EPM2A protein CTD PMID:35357534 NCBI chr10:11,218,435...11,335,408
Ensembl chr10:11,219,148...11,335,388 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP senecionine results in increased expression of ERP29 protein CTD PMID:35357534 NCBI chr 5:121,582,816...121,590,537
Ensembl chr 5:121,566,653...121,590,569 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO senecionine results in increased expression of ESCO2 mRNA CTD PMID:32419051 NCBI chr14:66,056,476...66,071,418
Ensembl chr14:66,056,487...66,071,443 		JBrowse link
G Esrra estrogen related receptor, alpha decreases expression EXP senecionine results in decreased expression of ESRRA protein CTD PMID:35357534 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208 		JBrowse link
G Ethe1 ethylmalonic encephalopathy 1 decreases expression ISO senecionine results in decreased expression of ETHE1 mRNA CTD PMID:32419051 NCBI chr 7:24,286,968...24,308,350
Ensembl chr 7:24,286,968...24,308,350 		JBrowse link
G Etnppl ethanolamine phosphate phospholyase increases expression EXP senecionine results in increased expression of ETNPPL protein CTD PMID:35357534 NCBI chr 3:130,411,097...130,429,399
Ensembl chr 3:130,411,097...130,431,170 		JBrowse link
G Ets2 E26 avian leukemia oncogene 2, 3' domain increases expression EXP senecionine results in increased expression of ETS2 protein CTD PMID:35357534 NCBI chr16:95,503,274...95,522,093
Ensembl chr16:95,502,942...95,522,095 		JBrowse link
G Etv6 ets variant 6 decreases expression EXP senecionine results in decreased expression of ETV6 protein CTD PMID:35357534 NCBI chr 6:134,012,663...134,247,121
Ensembl chr 6:134,012,663...134,247,121 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression EXP senecionine results in decreased expression of EXT1 protein CTD PMID:35357534 NCBI chr15:52,931,657...53,209,579
Ensembl chr15:52,927,434...53,209,555 		JBrowse link
G F13a1 coagulation factor XIII, A1 subunit increases expression EXP senecionine results in increased expression of F13A1 protein CTD PMID:35357534 NCBI chr13:37,051,150...37,234,220
Ensembl chr13:37,051,152...37,234,220 		JBrowse link
G Fahd2a fumarylacetoacetate hydrolase domain containing 2A increases expression EXP senecionine results in increased expression of FAHD2A protein CTD PMID:35357534 NCBI chr 2:127,278,135...127,286,491
Ensembl chr 2:127,278,135...127,286,485 		JBrowse link
G Fancd2 Fanconi anemia, complementation group D2 increases expression ISO senecionine results in increased expression of FANCD2 mRNA CTD PMID:32419051 NCBI chr 6:113,508,622...113,573,981
Ensembl chr 6:113,508,643...113,573,978 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO senecionine metabolite results in increased expression of FAS mRNA
senecionine results in increased expression of FAS mRNA		 CTD PMID:30465738 PMID:32419051 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fbxo21 F-box protein 21 increases expression EXP senecionine results in increased expression of FBXO21 protein CTD PMID:35357534 NCBI chr 5:118,114,835...118,148,263
Ensembl chr 5:118,114,795...118,148,266 		JBrowse link
G Fcgr4 Fc receptor, IgG, low affinity IV increases expression ISO senecionine results in increased expression of FCGR3A mRNA CTD PMID:34185104 NCBI chr 1:170,846,495...170,857,330
Ensembl chr 1:170,846,489...170,857,330 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP senecionine results in decreased expression of FDFT1 protein CTD PMID:35357534 NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027 		JBrowse link
G Fgl1 fibrinogen-like protein 1 decreases expression EXP senecionine results in decreased expression of FGL1 protein CTD PMID:35357534 NCBI chr 8:41,644,471...41,671,015
Ensembl chr 8:41,644,471...41,668,193 		JBrowse link
G Fis1 fission, mitochondrial 1 decreases expression EXP senecionine results in decreased expression of FIS1 protein CTD PMID:35357534 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088 		JBrowse link
G Fmo3 flavin containing monooxygenase 3 increases expression EXP senecionine results in increased expression of FMO3 protein CTD PMID:35357534 NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097 		JBrowse link
G Fmo4 flavin containing monooxygenase 4 decreases expression ISO senecionine results in decreased expression of FMO4 mRNA CTD PMID:26100227 NCBI chr 1:162,620,757...162,643,788
Ensembl chr 1:162,620,757...162,641,541 		JBrowse link
G Fmo5 flavin containing monooxygenase 5 decreases expression ISO senecionine results in decreased expression of FMO5 mRNA CTD PMID:26100227 NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 decreases expression EXP senecionine results in decreased expression of FMR1 protein CTD PMID:35357534 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression EXP senecionine results in decreased expression of FNDC3B protein CTD PMID:35357534 NCBI chr 3:27,470,284...27,765,469
Ensembl chr 3:27,470,311...27,765,456 		JBrowse link
G Folr2 folate receptor beta decreases expression EXP senecionine results in decreased expression of FOLR2 protein CTD PMID:35357534 NCBI chr 7:101,489,195...101,506,397
Ensembl chr 7:101,489,195...101,506,401 		JBrowse link
G Frmd4b FERM domain containing 4B decreases expression EXP senecionine results in decreased expression of FRMD4B protein CTD PMID:35357534 NCBI chr 6:97,263,828...97,594,618
Ensembl chr 6:97,263,828...97,594,502 		JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 decreases expression EXP senecionine results in decreased expression of FTSJ3 protein CTD PMID:35357534 NCBI chr11:106,139,964...106,146,910
Ensembl chr11:106,139,968...106,146,905 		JBrowse link
G Fyb2 FYN binding protein 2 decreases expression EXP senecionine results in decreased expression of FYB2 protein CTD PMID:35357534 NCBI chr 4:104,692,431...104,874,061
Ensembl chr 4:104,770,653...104,874,060 		JBrowse link
G Fyttd1 forty-two-three domain containing 1 decreases expression EXP senecionine results in decreased expression of FYTTD1 protein CTD PMID:35357534 NCBI chr16:32,697,762...32,729,333
Ensembl chr16:32,697,870...32,729,245 		JBrowse link
G G0s2 G0/G1 switch gene 2 increases expression EXP senecionine results in increased expression of G0S2 protein CTD PMID:35357534 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525 		JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases expression EXP senecionine results in increased expression of G6PDX protein CTD PMID:35357534 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800 		JBrowse link
G Gc vitamin D binding protein decreases expression EXP senecionine results in decreased expression of GC protein CTD PMID:35357534 NCBI chr 5:89,565,370...89,605,757
Ensembl chr 5:89,565,381...89,605,757 		JBrowse link
G Gckr glucokinase regulatory protein increases expression EXP senecionine results in increased expression of GCKR protein CTD PMID:35357534 NCBI chr 5:31,454,594...31,484,646
Ensembl chr 5:31,454,787...31,484,658 		JBrowse link
G Gcsh glycine cleavage system protein H (aminomethyl carrier) increases expression EXP senecionine results in increased expression of GCSH protein CTD PMID:35357534 NCBI chr 8:117,708,706...117,720,237
Ensembl chr 8:117,708,549...117,720,276 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO senecionine results in increased expression of GEM mRNA CTD PMID:26100227 NCBI chr 4:11,702,379...11,714,993
Ensembl chr 4:11,704,457...11,714,752 		JBrowse link
G Ghr growth hormone receptor decreases expression EXP senecionine results in decreased expression of GHR protein CTD PMID:35357534 NCBI chr15:3,347,237...3,612,834
Ensembl chr15:3,347,242...3,612,974 		JBrowse link
G Gls glutaminase increases expression ISO senecionine results in increased expression of GLS mRNA CTD PMID:26100227 NCBI chr 1:52,202,608...52,274,168
Ensembl chr 1:52,202,607...52,272,391 		JBrowse link
G Glyat glycine-N-acyltransferase decreases expression ISO senecionine results in decreased expression of GLYAT mRNA CTD PMID:26100227 NCBI chr19:12,610,672...12,629,101
Ensembl chr19:12,610,672...12,631,275 		JBrowse link
G Gnmt glycine N-methyltransferase increases expression ISO senecionine results in increased expression of GNMT mRNA CTD PMID:26100227 NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094 		JBrowse link
G Gpatch4 G patch domain containing 4 increases expression EXP senecionine results in increased expression of GPATCH4 protein CTD PMID:35357534 NCBI chr 3:87,950,413...87,963,301
Ensembl chr 3:87,950,415...87,963,300 		JBrowse link
G Gpc1 glypican 1 decreases expression ISO senecionine results in decreased expression of GPC1 mRNA CTD PMID:34185104 NCBI chr 1:92,759,367...92,787,933
Ensembl chr 1:92,759,367...92,788,501 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression EXP senecionine results in increased expression of GPCPD1 protein CTD PMID:35357534 NCBI chr 2:132,371,002...132,420,173
Ensembl chr 2:132,371,002...132,429,649 		JBrowse link
G Gphn gephyrin decreases expression ISO senecionine results in decreased expression of GPHN mRNA CTD PMID:26100227 NCBI chr12:78,264,099...78,731,546
Ensembl chr12:78,273,153...78,731,546 		JBrowse link
G Gprc5a G protein-coupled receptor, family C, group 5, member A increases expression ISO senecionine results in increased expression of GPRC5A mRNA CTD PMID:26100227 NCBI chr 6:135,042,660...135,061,707
Ensembl chr 6:135,042,649...135,061,707 		JBrowse link
G Gpsm3 G-protein signalling modulator 3 (AGS3-like, C. elegans) increases expression EXP senecionine results in increased expression of GPSM3 protein CTD PMID:35357534 NCBI chr17:34,808,780...34,810,728
Ensembl chr17:34,808,780...34,810,728 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble increases activity
multiple interactions
increases expression		 ISO
EXP		 senecionine results in increased activity of GPT protein
POR protein affects the reaction [senecionine results in increased expression of GPT protein]		 CTD PMID:24641316 PMID:31606820 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) increases expression ISO senecionine results in increased expression of GRIA3 mRNA CTD PMID:32419051 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478 		JBrowse link
G Grn granulin decreases expression EXP senecionine results in decreased expression of GRN protein CTD PMID:35357534 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression EXP senecionine results in increased expression of GRPEL1 protein CTD PMID:35357534 NCBI chr 5:36,622,529...36,631,421
Ensembl chr 5:36,622,342...36,631,424 		JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 increases expression EXP senecionine results in increased expression of GSTA1 protein CTD PMID:35357534 NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 decreases expression ISO senecionine results in decreased expression of GSTT1 mRNA CTD PMID:26100227 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Gzma granzyme A decreases expression ISO senecionine results in decreased expression of GZMA mRNA CTD PMID:32419051 NCBI chr13:113,230,358...113,237,515
Ensembl chr13:113,230,359...113,237,515 		JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression EXP senecionine results in decreased expression of H1-4 protein CTD PMID:35357534 NCBI chr13:23,805,760...23,806,541
Ensembl chr13:23,804,612...23,806,541 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO senecionine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374 		JBrowse link
G Haus2 HAUS augmin-like complex, subunit 2 decreases expression EXP senecionine results in decreased expression of HAUS2 protein CTD PMID:35357534 NCBI chr 2:120,439,863...120,452,041
Ensembl chr 2:120,439,864...120,452,041 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases expression EXP senecionine results in increased expression of HBA protein CTD PMID:35357534 NCBI chr11:32,233,672...32,234,486
Ensembl chr11:32,233,511...32,234,465 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain increases expression EXP senecionine results in increased expression of HBB-B1 protein CTD PMID:35357534
G Hc hemolytic complement decreases expression EXP senecionine results in decreased expression of C5 protein CTD PMID:35357534 NCBI chr 2:34,873,341...34,958,518
Ensembl chr 2:34,873,343...34,951,450 		JBrowse link
G Hdlbp high density lipoprotein (HDL) binding protein decreases expression EXP senecionine results in decreased expression of HDLBP protein CTD PMID:35357534 NCBI chr 1:93,333,662...93,406,639
Ensembl chr 1:93,333,662...93,406,537 		JBrowse link
G Herc6 hect domain and RLD 6 increases expression ISO senecionine results in increased expression of HERC6 mRNA CTD PMID:32419051 NCBI chr 6:57,557,977...57,642,121
Ensembl chr 6:57,557,985...57,641,617 		JBrowse link
G Hic2 hypermethylated in cancer 2 decreases expression EXP senecionine results in decreased expression of HIC2 protein CTD PMID:35357534 NCBI chr16:17,051,451...17,081,294
Ensembl chr16:17,051,436...17,081,294 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression EXP senecionine results in decreased expression of HMGCR protein CTD PMID:35357534 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Hmmr hyaluronan mediated motility receptor (RHAMM) increases expression ISO senecionine results in increased expression of HMMR mRNA CTD PMID:32419051 NCBI chr11:40,592,215...40,624,290
Ensembl chr11:40,592,222...40,624,249 		JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP senecionine results in decreased expression of HNF1A protein CTD PMID:35357534 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO senecionine results in decreased expression of HNMT mRNA CTD PMID:26100227 NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 increases expression EXP senecionine results in increased expression of HOGA1 protein CTD PMID:35357534 NCBI chr19:42,033,998...42,060,128
Ensembl chr19:42,034,049...42,059,392 		JBrowse link
G Hp haptoglobin decreases expression EXP senecionine results in decreased expression of HP protein CTD PMID:35357534 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP senecionine results in increased expression of HSD3B1 protein CTD PMID:35357534 NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110 		JBrowse link
G Hsf1 heat shock factor 1 increases activity ISO senecionine results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113 		JBrowse link
G Hypk huntingtin interacting protein K decreases expression EXP senecionine results in decreased expression of HYPK protein CTD PMID:35357534 NCBI chr 2:121,287,569...121,288,921
Ensembl chr 2:121,283,771...121,289,153 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO senecionine results in increased expression of ICAM1 mRNA CTD PMID:35357534 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO senecionine results in increased expression of IFIT2 mRNA CTD PMID:32419051 NCBI chr19:34,527,961...34,553,934
Ensembl chr19:34,528,094...34,553,819 		JBrowse link
G Ift25 intraflagellar transport 25 increases expression EXP senecionine results in increased expression of IFT25 protein CTD PMID:35357534 NCBI chr 4:107,110,889...107,137,135
Ensembl chr 4:107,110,790...107,137,135 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression EXP senecionine results in decreased expression of IGFBP4 protein CTD PMID:35357534 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) increases expression EXP senecionine results in increased expression of IGHG1 protein CTD PMID:35357534 NCBI chr12:113,290,161...113,294,143
Ensembl chr12:113,288,860...113,294,143 		JBrowse link
G Ighg2b immunoglobulin heavy constant gamma 2B increases expression EXP senecionine results in increased expression of IGHG2B protein CTD PMID:35357534 NCBI chr12:113,267,934...113,271,553
Ensembl chr12:113,266,585...113,271,553 		JBrowse link
G Il11 interleukin 11 increases expression ISO senecionine metabolite results in increased expression of IL11 mRNA CTD PMID:30465738 NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 decreases expression EXP senecionine results in decreased expression of IL13RA1 protein CTD PMID:35357534 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO senecionine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr14:26,760,990...26,829,243
Ensembl chr14:26,760,898...26,829,243 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO senecionine metabolite results in increased expression of IL1B mRNA CTD PMID:30465738 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6st interleukin 6 signal transducer decreases expression EXP senecionine results in decreased expression of IL6ST protein CTD PMID:35357534 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression EXP senecionine results in increased expression of IMPDH2 protein CTD PMID:35357534 NCBI chr 9:108,437,635...108,442,776
Ensembl chr 9:108,437,485...108,442,783 		JBrowse link
G Inip INTS3 and NABP interacting protein decreases expression EXP senecionine results in decreased expression of INIP protein CTD PMID:35357534 NCBI chr 4:59,769,637...59,783,855
Ensembl chr 4:59,769,637...59,801,589 		JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression ISO senecionine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 6:55,147,612...55,151,975
Ensembl chr 6:55,147,611...55,152,028 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 increases expression EXP senecionine results in increased expression of ISCA1 protein CTD PMID:35357534 NCBI chr13:59,903,229...59,917,603
Ensembl chr13:59,903,223...59,917,624 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression EXP senecionine results in increased expression of ISG15 protein CTD PMID:35357534 NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253 		JBrowse link
G Isg20 interferon-stimulated protein increases expression ISO senecionine results in increased expression of ISG20 mRNA CTD PMID:26100227 NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144 		JBrowse link
G Itgam integrin alpha M increases expression EXP senecionine results in increased expression of ITGAM protein CTD PMID:35357534 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663 		JBrowse link
G Itgb2l integrin beta 2-like increases expression EXP senecionine results in increased expression of ITGB2L protein CTD PMID:35357534 NCBI chr16:96,223,488...96,244,861
Ensembl chr16:96,223,488...96,244,819 		JBrowse link
G Itih2 inter-alpha trypsin inhibitor, heavy chain 2 decreases expression EXP senecionine results in decreased expression of ITIH2 protein CTD PMID:35357534 NCBI chr 2:10,099,408...10,135,492
Ensembl chr 2:10,099,404...10,136,207 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression EXP senecionine results in decreased expression of ITIH3 protein CTD PMID:35357534 NCBI chr14:30,630,529...30,645,748
Ensembl chr14:30,630,529...30,645,717 		JBrowse link
G Itm2b integral membrane protein 2B decreases expression EXP senecionine results in decreased expression of ITM2B protein CTD PMID:35357534 NCBI chr14:73,599,666...73,622,729
Ensembl chr14:73,599,666...73,622,729 		JBrowse link
G Jam3 junction adhesion molecule 3 increases expression ISO senecionine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 9:27,008,680...27,066,739
Ensembl chr 9:27,008,680...27,066,717 		JBrowse link
G Jchain immunoglobulin joining chain decreases expression EXP senecionine results in decreased expression of JCHAIN protein CTD PMID:35357534 NCBI chr 5:88,667,663...88,675,667
Ensembl chr 5:88,667,668...88,675,750 		JBrowse link
G Jmjd6 jumonji domain containing 6 increases expression EXP senecionine results in increased expression of JMJD6 protein CTD PMID:35357534 NCBI chr11:116,728,258...116,734,593
Ensembl chr11:116,728,258...116,734,275 		JBrowse link
G Junb jun B proto-oncogene increases expression EXP senecionine results in increased expression of JUNB protein CTD PMID:35357534 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347 		JBrowse link
G Kif11 kinesin family member 11 increases expression ISO senecionine results in increased expression of KIF11 mRNA CTD PMID:32419051 NCBI chr19:37,364,830...37,410,311
Ensembl chr19:37,364,851...37,410,307 		JBrowse link
G Kif18a kinesin family member 18A increases expression ISO senecionine results in increased expression of KIF18A mRNA CTD PMID:32419051 NCBI chr 2:109,111,165...109,172,094
Ensembl chr 2:109,111,083...109,172,092 		JBrowse link
G Knl1 kinetochore scaffold 1 increases expression ISO senecionine results in increased expression of KNL1 mRNA CTD PMID:32419051 NCBI chr 2:118,877,600...118,940,978
Ensembl chr 2:118,877,600...118,935,982 		JBrowse link
G Kntc1 kinetochore associated 1 increases expression ISO senecionine results in increased expression of KNTC1 mRNA CTD PMID:32419051 NCBI chr 5:123,887,755...123,959,656
Ensembl chr 5:123,887,779...123,959,656 		JBrowse link
G Krt19 keratin 19 decreases expression EXP senecionine results in decreased expression of KRT19 protein CTD PMID:35357534 NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491 		JBrowse link
G Ktn1 kinectin 1 decreases expression EXP senecionine results in decreased expression of KTN1 protein CTD PMID:35357534 NCBI chr14:47,886,551...47,974,021
Ensembl chr14:47,885,905...47,977,351 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO senecionine results in decreased expression of KYAT1 mRNA CTD PMID:26100227 NCBI chr 2:30,075,136...30,096,307
Ensembl chr 2:30,075,136...30,095,859 		JBrowse link
G Larp4 La ribonucleoprotein 4 decreases expression EXP senecionine results in decreased expression of LARP4 protein CTD PMID:35357534 NCBI chr15:99,867,946...99,914,239
Ensembl chr15:99,867,946...99,914,239 		JBrowse link
G Lbp lipopolysaccharide binding protein increases expression ISO senecionine results in increased expression of LBP mRNA CTD PMID:32419051 NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772 		JBrowse link
G Lcn2 lipocalin 2 increases expression EXP senecionine results in increased expression of LCN2 mRNA CTD PMID:31606820 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264 		JBrowse link
G Lgals2 lectin, galactose-binding, soluble 2 decreases expression EXP senecionine results in decreased expression of LGALS2 protein CTD PMID:35357534 NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729 		JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 decreases expression EXP senecionine results in decreased expression of LGR5 mRNA CTD PMID:31606820 NCBI chr10:115,286,219...115,423,685
Ensembl chr10:115,286,216...115,423,685 		JBrowse link
G Lin37 lin-37 DREAM MuvB core complex component decreases expression EXP senecionine results in decreased expression of LIN37 protein CTD PMID:35357534 NCBI chr 7:30,254,866...30,259,289
Ensembl chr 7:30,254,866...30,259,263 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression EXP senecionine results in increased expression of LONP1 protein CTD PMID:35357534 NCBI chr17:56,921,297...56,933,903
Ensembl chr17:56,921,297...56,933,887 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 decreases expression EXP senecionine results in decreased expression of LRP1 protein CTD PMID:35357534 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 decreases expression EXP senecionine results in decreased expression of LRRC59 protein CTD PMID:35357534 NCBI chr11:94,520,603...94,536,049
Ensembl chr11:94,520,593...94,536,042 		JBrowse link
G Ltf lactotransferrin increases expression EXP senecionine results in increased expression of LTF protein CTD PMID:35357534 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835 		JBrowse link
G Lyz2 lysozyme 2 increases expression EXP senecionine results in increased expression of LYZ2 protein CTD PMID:35357534 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Maco1 macoilin 1 decreases expression EXP senecionine results in decreased expression of MACO1 protein CTD PMID:35357534 NCBI chr 4:134,530,070...134,581,242
Ensembl chr 4:134,530,070...134,580,656 		JBrowse link
G Mad2l1 MAD2 mitotic arrest deficient-like 1 increases expression ISO senecionine results in increased expression of MAD2L1 mRNA CTD PMID:32419051 NCBI chr 6:66,512,205...66,518,091
Ensembl chr 6:66,512,374...66,524,204 		JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO
EXP		 senecionine results in increased expression of MAFF mRNA
senecionine results in increased expression of MAFF protein		 CTD PMID:26100227 PMID:35357534 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276 		JBrowse link
G Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) increases expression EXP senecionine results in increased expression of MAFK protein CTD PMID:35357534 NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408 		JBrowse link
G Mal myelin and lymphocyte protein, T cell differentiation protein increases expression ISO senecionine results in increased expression of MAL mRNA CTD PMID:34185104 NCBI chr 2:127,475,146...127,498,615
Ensembl chr 2:127,475,146...127,498,615 		JBrowse link
G Maoa monoamine oxidase A decreases expression ISO senecionine results in decreased expression of MAOA mRNA CTD PMID:26100227 NCBI chr  X:16,485,937...16,554,051
Ensembl chr  X:16,485,937...16,554,057 		JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 increases expression EXP senecionine results in increased expression of MAP2K3 protein CTD PMID:35357534 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637 		JBrowse link
G Map7 microtubule-associated protein 7 decreases expression EXP senecionine results in decreased expression of MAP7 protein CTD PMID:35357534 NCBI chr10:20,024,666...20,157,336
Ensembl chr10:20,024,217...20,157,336 		JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 decreases expression EXP senecionine results in decreased expression of MAPRE2 protein CTD PMID:35357534 NCBI chr18:23,885,390...24,026,918
Ensembl chr18:23,885,390...24,026,918 		JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression ISO senecionine results in increased expression of MASTL mRNA CTD PMID:32419051 NCBI chr 2:23,006,549...23,046,036
Ensembl chr 2:23,005,618...23,046,036 		JBrowse link
G Mbl2 mannose-binding lectin (protein C) 2 increases expression EXP senecionine results in increased expression of MBL2 protein CTD PMID:35357534 NCBI chr19:30,210,306...30,217,087
Ensembl chr19:30,210,342...30,217,087 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO senecionine results in increased expression of MCM3 mRNA CTD PMID:32419051 NCBI chr 1:20,873,188...20,890,536
Ensembl chr 1:20,873,192...20,890,536 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression ISO senecionine results in increased expression of MCM5 mRNA CTD PMID:32419051 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067 		JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine increases expression EXP senecionine results in increased expression of METTL21A protein CTD PMID:35357534 NCBI chr 1:64,645,632...64,661,926
Ensembl chr 1:64,645,632...64,656,401 		JBrowse link
G Mgat5 mannoside acetylglucosaminyltransferase 5 decreases expression EXP senecionine results in decreased expression of MGAT5 protein CTD PMID:35357534 NCBI chr 1:127,132,450...127,413,760
Ensembl chr 1:127,132,752...127,416,073 		JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 increases expression EXP senecionine results in increased expression of MGME1 protein CTD PMID:35357534 NCBI chr 2:144,112,824...144,123,147
Ensembl chr 2:144,112,583...144,123,147 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression ISO senecionine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mib2 mindbomb E3 ubiquitin protein ligase 2 decreases expression EXP senecionine results in decreased expression of MIB2 protein CTD PMID:35357534 NCBI chr 4:155,738,925...155,753,711
Ensembl chr 4:155,739,134...155,753,655 		JBrowse link
G Micos10 mitochondrial contact site and cristae organizing system subunit 10 decreases expression EXP senecionine results in decreased expression of MICOS10 protein CTD PMID:35357534 NCBI chr 4:138,829,125...138,858,667
Ensembl chr 4:138,829,125...138,858,424 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 increases expression ISO senecionine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO senecionine results in increased expression of MMP1 mRNA CTD PMID:26100227 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions		 EXP
ISO		 senecionine results in increased expression of MMP9 mRNA; senecionine results in increased expression of MMP9 protein
Leu-Ser-Lys-Leu peptide inhibits the reaction [senecionine results in increased expression of MMP9 mRNA]		 CTD PMID:35357534 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Mmrn1 multimerin 1 increases expression EXP senecionine results in increased expression of MMRN1 protein CTD PMID:35357534 NCBI chr 6:60,921,301...60,966,362
Ensembl chr 6:60,901,960...60,966,362 		JBrowse link
G Mpdu1 mannose-P-dolichol utilization defect 1 decreases expression EXP senecionine results in decreased expression of MPDU1 protein CTD PMID:35357534 NCBI chr11:69,547,523...69,553,475
Ensembl chr11:69,547,523...69,553,468 		JBrowse link
G Mpo myeloperoxidase increases expression EXP senecionine results in increased expression of MPO protein CTD PMID:35357534 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239 		JBrowse link
G Mpst mercaptopyruvate sulfurtransferase increases expression EXP senecionine results in increased expression of MPST protein CTD PMID:35357534 NCBI chr15:78,290,918...78,298,213
Ensembl chr15:78,290,616...78,298,213 		JBrowse link
G Mrpl42 mitochondrial ribosomal protein L42 increases expression EXP senecionine results in increased expression of MRPL42 protein CTD PMID:35357534 NCBI chr10:95,316,667...95,337,811
Ensembl chr10:95,316,667...95,337,802 		JBrowse link
G Msmo1 methylsterol monoxygenase 1 decreases expression EXP senecionine results in decreased expression of MSMO1 protein CTD PMID:35357534 NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826 		JBrowse link
G mt-Co3 cytochrome c oxidase III, mitochondrial increases expression EXP senecionine results in increased expression of COX3 protein CTD PMID:35357534 NCBI chr MT:8,607...9,390
Ensembl chr MT:8,607...9,390 		JBrowse link
G mt-Nd3 NADH dehydrogenase 3, mitochondrial decreases expression EXP senecionine results in decreased expression of ND3 protein CTD PMID:35357534 NCBI chr MT:9,459...9,806
Ensembl chr MT:9,459...9,806 		JBrowse link
G Mt2 metallothionein 2 increases expression EXP senecionine results in increased expression of MT2 mRNA CTD PMID:31606820 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression EXP senecionine results in increased expression of MTHFD1L protein CTD PMID:35357534 NCBI chr10:3,918,282...4,117,081
Ensembl chr10:3,923,118...4,117,081 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression EXP senecionine results in decreased expression of MTSS1 protein CTD PMID:35357534 NCBI chr15:58,813,083...58,955,805
Ensembl chr15:58,813,083...58,953,854 		JBrowse link
G Mtus1 mitochondrial tumor suppressor 1 decreases expression EXP senecionine results in decreased expression of MTUS1 protein CTD PMID:35357534 NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763 		JBrowse link
G Mybl1 myeloblastosis oncogene-like 1 increases expression ISO senecionine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 1:9,737,632...9,770,664
Ensembl chr 1:9,737,640...9,770,434 		JBrowse link
G Mybl2 myeloblastosis oncogene-like 2 increases expression ISO senecionine results in increased expression of MYBL2 mRNA CTD PMID:32419051 NCBI chr 2:162,896,246...162,926,608
Ensembl chr 2:162,896,607...162,926,608 		JBrowse link
G Mybpc3 myosin binding protein C, cardiac decreases expression ISO senecionine results in decreased expression of MYBPC3 mRNA CTD PMID:34185104 NCBI chr 2:90,948,459...90,966,862
Ensembl chr 2:90,948,489...90,966,861 		JBrowse link
G Myoz2 myozenin 2 decreases expression ISO senecionine results in decreased expression of MYOZ2 mRNA CTD PMID:34185104 NCBI chr 3:122,799,855...122,828,649
Ensembl chr 3:122,799,855...122,828,664 		JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression EXP senecionine results in decreased expression of N4BP2L1 protein CTD PMID:35357534 NCBI chr 5:150,495,108...150,518,288
Ensembl chr 5:150,495,109...150,520,653 		JBrowse link
G Napsa napsin A aspartic peptidase increases expression EXP senecionine results in increased expression of NAPSA protein CTD PMID:35357534 NCBI chr 7:44,221,869...44,236,270
Ensembl chr 7:44,221,804...44,236,286 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO senecionine results in increased expression of NCAPH mRNA CTD PMID:32419051 NCBI chr 2:126,945,729...126,975,857
Ensembl chr 2:126,945,729...126,975,874 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 increases expression EXP senecionine results in increased expression of NCF4 protein CTD PMID:35357534 NCBI chr15:78,128,324...78,146,782
Ensembl chr15:78,129,001...78,146,780 		JBrowse link
G Ndc80 NDC80 kinetochore complex component increases expression ISO senecionine results in increased expression of NDC80 mRNA CTD PMID:32419051 NCBI chr17:71,803,095...71,833,852
Ensembl chr17:71,803,095...71,833,852 		JBrowse link
G Neb nebulin decreases expression ISO senecionine results in decreased expression of NEB mRNA CTD PMID:26100227 NCBI chr 2:52,026,652...52,228,810
Ensembl chr 2:52,026,659...52,268,486 		JBrowse link
G Nfia nuclear factor I/A decreases expression EXP senecionine results in decreased expression of NFIA protein CTD PMID:35357534 NCBI chr 4:97,469,534...98,007,113
Ensembl chr 4:97,660,971...98,007,111 		JBrowse link
G Ngp neutrophilic granule protein increases expression EXP senecionine results in increased expression of NGP protein CTD PMID:35357534 NCBI chr 9:110,248,876...110,252,080
Ensembl chr 9:110,248,815...110,252,080 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression EXP senecionine results in decreased expression of NIFK protein CTD PMID:35357534 NCBI chr 1:118,249,573...118,261,561
Ensembl chr 1:118,249,569...118,261,552 		JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO senecionine results in decreased expression of NNMT mRNA CTD PMID:26100227 NCBI chr 9:48,448,905...48,518,958
Ensembl chr 9:48,503,177...48,516,453 		JBrowse link
G Nop16 NOP16 nucleolar protein decreases expression EXP senecionine results in decreased expression of NOP16 protein CTD PMID:35357534 NCBI chr13:54,732,004...54,737,921
Ensembl chr13:54,731,998...54,737,903 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression ISO senecionine results in increased expression of NOS2 mRNA CTD PMID:35357534 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase increases expression EXP senecionine results in increased expression of NPL protein CTD PMID:35357534 NCBI chr 1:153,378,762...153,425,460
Ensembl chr 1:153,378,761...153,425,791 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO senecionine results in increased expression of NQO1 mRNA CTD PMID:26100227 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO
EXP		 senecionine results in decreased expression of NR0B2 mRNA CTD PMID:24641316 PMID:31606820 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP senecionine results in increased expression of NR1D1 protein CTD PMID:35357534 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression ISO
EXP		 senecionine results in decreased expression of NR1H4 mRNA
senecionine results in decreased expression of NR1H4 protein		 CTD PMID:24641316 PMID:35357534 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression EXP senecionine results in decreased expression of NR1I3 mRNA CTD PMID:31606820 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO senecionine results in decreased expression of NR3C1 mRNA CTD PMID:32419051 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474 		JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression ISO senecionine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr12:44,375,568...44,651,977
Ensembl chr12:44,375,668...44,648,747 		JBrowse link
G Nrg1 neuregulin 1 increases expression ISO senecionine results in increased expression of NRG1 mRNA CTD PMID:32419051 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825 		JBrowse link
G Nrp1 neuropilin 1 decreases expression EXP senecionine results in decreased expression of NRP1 protein CTD PMID:35357534 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844 		JBrowse link
G Ntm neurotrimin decreases expression EXP senecionine results in decreased expression of NTM protein CTD PMID:35357534 NCBI chr 9:28,906,045...29,874,565
Ensembl chr 9:28,906,046...29,874,437 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases expression EXP senecionine results in decreased expression of NUCKS1 protein CTD PMID:35357534 NCBI chr 1:131,838,196...131,864,059
Ensembl chr 1:131,838,272...131,864,059 		JBrowse link
G Nudt7 nudix hydrolase 7 increases expression EXP senecionine results in increased expression of NUDT7 protein CTD PMID:35357534 NCBI chr 8:114,860,314...114,881,471
Ensembl chr 8:114,860,297...114,881,479 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression ISO senecionine results in increased expression of NUSAP1 mRNA CTD PMID:32419051 NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725 		JBrowse link
G Orm1 orosomucoid 1 decreases expression EXP senecionine results in decreased expression of ORM1 protein CTD PMID:35357534 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400 		JBrowse link
G Orm2 orosomucoid 2 decreases expression EXP senecionine results in decreased expression of ORM2 protein CTD PMID:35357534 NCBI chr 4:63,280,543...63,284,114
Ensembl chr 4:63,280,686...63,284,115 		JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial increases expression EXP senecionine results in increased expression of OXSM protein CTD PMID:35357534 NCBI chr14:6,219,955...6,231,111
Ensembl chr14:6,219,955...6,231,111 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression EXP senecionine results in decreased expression of PABPC1 protein CTD PMID:35357534 NCBI chr15:36,595,902...36,609,825
Ensembl chr15:36,595,905...36,609,912 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 decreases expression ISO
EXP		 senecionine results in decreased expression of PARP1 protein CTD PMID:29458164 PMID:35357534 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO senecionine results in increased expression of PCLAF mRNA CTD PMID:32419051 NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression EXP senecionine results in decreased expression of PCSK9 protein CTD PMID:35357534 NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526 		JBrowse link
G Pdcl phosducin-like increases expression EXP senecionine results in increased expression of PDCL protein CTD PMID:35357534 NCBI chr 2:37,240,086...37,249,832
Ensembl chr 2:37,240,086...37,249,344 		JBrowse link
G Pde12 phosphodiesterase 12 increases expression EXP senecionine results in increased expression of PDE12 protein CTD PMID:35357534 NCBI chr14:26,381,113...26,390,823
Ensembl chr14:26,381,113...26,391,038 		JBrowse link
G Pde7b phosphodiesterase 7B decreases expression EXP senecionine results in decreased expression of PDE7B protein CTD PMID:35357534 NCBI chr10:20,272,798...20,600,824
Ensembl chr10:20,273,750...20,600,824 		JBrowse link
G Pdia2 protein disulfide isomerase associated 2 decreases expression EXP senecionine results in decreased expression of PDIA2 protein CTD PMID:35357534 NCBI chr17:26,414,973...26,418,108
Ensembl chr17:26,414,973...26,418,061 		JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 decreases expression EXP senecionine results in decreased expression of PDZRN3 protein CTD PMID:35357534 NCBI chr 6:101,126,568...101,354,858
Ensembl chr 6:101,126,570...101,354,858 		JBrowse link
G Per3 period circadian clock 3 decreases expression EXP senecionine results in decreased expression of PER3 protein CTD PMID:35357534 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122 		JBrowse link
G Phf14 PHD finger protein 14 decreases expression EXP senecionine results in decreased expression of PHF14 protein CTD PMID:35357534 NCBI chr 6:11,907,728...12,100,155
Ensembl chr 6:11,907,808...12,081,204 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression EXP senecionine results in decreased expression of PID1 protein CTD PMID:35357534 NCBI chr 1:84,014,014...84,317,550
Ensembl chr 1:84,014,017...84,341,901 		JBrowse link
G Piezo1 piezo-type mechanosensitive ion channel component 1 increases expression EXP senecionine results in increased expression of PIEZO1 protein CTD PMID:35357534 NCBI chr 8:123,208,437...123,278,068
Ensembl chr 8:123,208,437...123,278,068 		JBrowse link
G Pigr polymeric immunoglobulin receptor decreases expression EXP senecionine results in decreased expression of PIGR protein CTD PMID:35357534 NCBI chr 1:130,754,421...130,779,986
Ensembl chr 1:130,754,421...130,779,986 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases expression EXP senecionine results in decreased expression of PKD2 protein CTD PMID:35357534 NCBI chr 5:104,599,379...104,653,685
Ensembl chr 5:104,607,316...104,653,685 		JBrowse link
G Plcg2 phospholipase C, gamma 2 increases expression EXP senecionine results in increased expression of PLCG2 protein CTD PMID:35357534 NCBI chr 8:118,225,014...118,361,881
Ensembl chr 8:118,225,030...118,361,881 		JBrowse link
G Pld1 phospholipase D1 decreases expression EXP senecionine results in decreased expression of PLD1 protein CTD PMID:35357534 NCBI chr 3:27,992,636...28,187,388
Ensembl chr 3:27,992,844...28,187,511 		JBrowse link
G Pld4 phospholipase D family member 4 increases expression ISO senecionine results in increased expression of PLD4 mRNA CTD PMID:34185104 NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424 		JBrowse link
G Plg plasminogen decreases expression EXP senecionine results in decreased expression of PLG protein CTD PMID:35357534 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Plin2 perilipin 2 increases expression EXP senecionine results in increased expression of PLIN2 protein CTD PMID:35357534 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297 		JBrowse link
G Plk4 polo like kinase 4 increases expression ISO senecionine results in increased expression of PLK4 mRNA CTD PMID:32419051 NCBI chr 3:40,754,463...40,771,318
Ensembl chr 3:40,754,454...40,771,318 		JBrowse link
G Pln phospholamban decreases expression ISO senecionine results in decreased expression of PLN mRNA CTD PMID:34185104 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083 		JBrowse link
G Pml promyelocytic leukemia decreases expression EXP senecionine results in decreased expression of PML protein CTD PMID:35357534 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP senecionine results in increased expression of PNPLA2 protein CTD PMID:35357534 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656 		JBrowse link
G Polr1g RNA polymerase I subunit G increases expression EXP senecionine results in increased expression of POLR1G protein CTD PMID:35357534 NCBI chr 7:19,089,932...19,093,408
Ensembl chr 7:19,089,939...19,093,408 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
affects response to substance		 EXP POR protein affects the reaction [senecionine results in increased expression of GPT protein]
POR protein affects the susceptibility to senecionine		 CTD PMID:31606820 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Ppif peptidylprolyl isomerase F (cyclophilin F) increases expression EXP senecionine results in increased expression of PPIF protein CTD PMID:35357534 NCBI chr14:25,693,998...25,700,892
Ensembl chr14:25,694,578...25,700,892 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP senecionine results in decreased expression of PPP1R3B protein CTD PMID:35357534 NCBI chr 8:35,842,847...35,855,293
Ensembl chr 8:35,842,893...35,855,293 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO senecionine results in increased expression of PRC1 mRNA CTD PMID:32419051 NCBI chr 7:79,944,224...79,966,007
Ensembl chr 7:79,944,198...79,966,007 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression EXP senecionine results in increased expression of PRDX3 protein CTD PMID:35357534 NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994 		JBrowse link
G Prg4 proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) decreases expression EXP senecionine results in decreased expression of PRG4 protein CTD PMID:35357534 NCBI chr 1:150,325,163...150,341,916
Ensembl chr 1:150,325,163...150,341,916 		JBrowse link
G Prlr prolactin receptor decreases expression EXP senecionine results in decreased expression of PRLR protein CTD PMID:35357534 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Prox1 prospero homeobox 1 decreases expression EXP senecionine results in decreased expression of PROX1 protein CTD PMID:35357534 NCBI chr 1:189,850,232...189,903,024
Ensembl chr 1:189,850,232...189,902,911 		JBrowse link
G Prr12 proline rich 12 decreases expression EXP senecionine results in decreased expression of PRR12 protein CTD PMID:35357534 NCBI chr 7:44,677,125...44,702,758
Ensembl chr 7:44,676,987...44,702,305 		JBrowse link
G Psap prosaposin decreases expression EXP senecionine results in decreased expression of PSAP protein CTD PMID:35357534 NCBI chr10:60,113,436...60,138,379
Ensembl chr10:60,113,449...60,138,376 		JBrowse link
G Psip1 PC4 and SFRS1 interacting protein 1 decreases expression EXP senecionine results in decreased expression of PSIP1 protein CTD PMID:35357534 NCBI chr 4:83,373,917...83,404,700
Ensembl chr 4:83,373,917...83,404,696 		JBrowse link
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 increases expression EXP senecionine results in increased expression of PSMD10 protein CTD PMID:35357534 NCBI chr  X:139,849,174...139,857,460
Ensembl chr  X:139,849,178...139,857,477 		JBrowse link
G Ptgis prostaglandin I2 (prostacyclin) synthase decreases expression ISO senecionine metabolite results in decreased expression of PTGIS mRNA; senecionine metabolite results in decreased expression of PTGIS protein CTD PMID:30465738 NCBI chr 2:167,045,114...167,095,069
Ensembl chr 2:167,033,725...167,082,524 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO senecionine metabolite results in increased expression of PTGS2 mRNA; senecionine metabolite results in increased expression of PTGS2 protein CTD PMID:30465738 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Ptprd protein tyrosine phosphatase receptor type D decreases expression ISO
EXP		 senecionine results in decreased expression of PTPRD mRNA
senecionine results in decreased expression of PTPRD protein		 CTD PMID:26100227 PMID:35357534 NCBI chr 4:75,859,474...78,132,282
Ensembl chr 4:75,859,475...78,130,198 		JBrowse link
G Rab11a RAB11A, member RAS oncogene family decreases expression EXP senecionine results in decreased expression of RAB11A protein CTD PMID:35357534 NCBI chr 9:64,622,582...64,645,038
Ensembl chr 9:64,622,581...64,645,040 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor (GEF) 4 decreases expression ISO senecionine results in decreased expression of RAPGEF4 mRNA CTD PMID:26100227 NCBI chr 2:71,811,559...72,087,818
Ensembl chr 2:71,811,584...72,087,818 		JBrowse link
G Rassf1 Ras association (RalGDS/AF-6) domain family member 1 increases expression EXP senecionine results in increased expression of RASSF1 protein CTD PMID:35357534 NCBI chr 9:107,428,752...107,439,460
Ensembl chr 9:107,428,754...107,439,466 		JBrowse link
G Rbis ribosomal biogenesis factor decreases expression EXP senecionine results in decreased expression of RBIS protein CTD PMID:35357534 NCBI chr 3:14,671,349...14,676,419
Ensembl chr 3:14,671,344...14,676,345 		JBrowse link
G Rbm3 RNA binding motif (RNP1, RRM) protein 3 decreases expression EXP senecionine results in decreased expression of RBM3 protein CTD PMID:35357534 NCBI chr  X:8,005,214...8,012,119
Ensembl chr  X:8,005,214...8,012,119 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 increases expression EXP senecionine results in increased expression of RC3H1 protein CTD PMID:35357534 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 decreases expression EXP senecionine results in decreased expression of RCL1 protein CTD PMID:35357534 NCBI chr19:29,078,761...29,121,251
Ensembl chr19:29,078,775...29,121,329 		JBrowse link
G Rexo4 REX4, 3'-5' exonuclease decreases expression EXP senecionine results in decreased expression of REXO4 protein CTD PMID:35357534 NCBI chr 2:26,843,575...26,854,398
Ensembl chr 2:26,843,575...26,854,398 		JBrowse link
G Ring1 ring finger protein 1 decreases expression EXP senecionine results in decreased expression of RING1 protein CTD PMID:35357534 NCBI chr17:34,239,766...34,243,654
Ensembl chr17:34,239,766...34,243,654 		JBrowse link
G Rpl34 ribosomal protein L34 decreases expression EXP senecionine results in decreased expression of RPL34 protein CTD PMID:35357534 NCBI chr 3:130,520,476...130,524,047
Ensembl chr 3:130,520,480...130,524,047 		JBrowse link
G Rpl36 ribosomal protein L36 decreases expression EXP senecionine results in decreased expression of RPL36 protein CTD PMID:35357534 NCBI chr17:56,917,094...56,921,246
Ensembl chr17:56,920,416...56,921,243 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 increases expression EXP senecionine results in increased expression of RPLP1 protein CTD PMID:35357534 NCBI chr 9:61,820,565...61,821,792
Ensembl chr 9:61,820,566...61,821,824 		JBrowse link
G Rps27 ribosomal protein S27 decreases expression EXP senecionine results in decreased expression of RPS27 protein CTD PMID:35357534 NCBI chr 3:90,119,974...90,120,955
Ensembl chr 3:90,119,829...90,120,958 		JBrowse link
G Rrad Ras-related associated with diabetes increases expression ISO senecionine results in increased expression of RRAD mRNA CTD PMID:26100227 NCBI chr 8:105,354,702...105,357,921
Ensembl chr 8:105,354,702...105,357,959 		JBrowse link
G Rragb Ras-related GTP binding B increases expression EXP senecionine results in increased expression of RRAGB protein CTD PMID:35357534 NCBI chr  X:151,920,640...151,973,188
Ensembl chr  X:151,922,977...151,954,939 		JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression EXP senecionine results in decreased expression of RRBP1 protein CTD PMID:35357534 NCBI chr 2:143,789,315...143,853,216
Ensembl chr 2:143,789,315...143,853,183 		JBrowse link
G Rrm1 ribonucleotide reductase M1 increases expression ISO senecionine results in increased expression of RRM1 mRNA CTD PMID:32419051 NCBI chr 7:102,090,902...102,118,978
Ensembl chr 7:102,090,902...102,118,978 		JBrowse link
G Rrn3 RRN3 RNA polymerase I transcription factor homolog (yeast) increases expression EXP senecionine results in increased expression of RRN3 protein CTD PMID:35357534 NCBI chr16:13,598,563...13,632,705
Ensembl chr16:13,598,572...13,632,703 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression EXP senecionine results in increased expression of RSAD2 protein CTD PMID:35357534 NCBI chr12:26,492,742...26,506,451
Ensembl chr12:26,492,745...26,506,451 		JBrowse link
G Rsl24d1 ribosomal L24 domain containing 1 decreases expression EXP senecionine results in decreased expression of RSL24D1 protein CTD PMID:35357534 NCBI chr 9:73,020,751...73,030,615
Ensembl chr 9:73,020,708...73,030,615 		JBrowse link
G Rxra retinoid X receptor alpha decreases expression EXP senecionine results in decreased expression of RXRA protein CTD PMID:35357534 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969 		JBrowse link
G S100a4 S100 calcium binding protein A4 increases expression EXP senecionine results in increased expression of S100A4 protein CTD PMID:35357534 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352 		JBrowse link
G S100a6 S100 calcium binding protein A6 (calcyclin) increases expression EXP senecionine results in increased expression of S100A6 protein CTD PMID:35357534 NCBI chr 3:90,520,491...90,531,797
Ensembl chr 3:90,520,189...90,531,488 		JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression EXP senecionine results in increased expression of S100A9 protein CTD PMID:35357534 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028 		JBrowse link
G Saa1 serum amyloid A 1 decreases expression EXP senecionine results in decreased expression of SAA1 protein CTD PMID:35357534 NCBI chr 7:46,389,921...46,392,404
Ensembl chr 7:46,389,921...46,392,404 		JBrowse link
G Saa2 serum amyloid A 2 decreases expression EXP senecionine results in decreased expression of SAA2 protein CTD PMID:35357534 NCBI chr 7:46,401,257...46,403,737
Ensembl chr 7:46,401,214...46,403,737 		JBrowse link
G Saa3 serum amyloid A 3 increases expression EXP senecionine results in increased expression of SAA3 mRNA CTD PMID:31606820 NCBI chr 7:46,361,422...46,365,100
Ensembl chr 7:46,361,422...46,365,124 		JBrowse link
G Saa4 serum amyloid A 4 decreases expression EXP senecionine results in decreased expression of SAA4 protein CTD PMID:35357534 NCBI chr 7:46,377,416...46,382,027
Ensembl chr 7:46,377,422...46,382,027 		JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression EXP senecionine results in decreased expression of SARNP protein CTD PMID:35357534 NCBI chr10:128,657,633...128,713,507
Ensembl chr10:128,653,202...128,713,498 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO senecionine results in increased expression of SAT1 mRNA CTD PMID:26100227 NCBI chr  X:153,996,128...153,999,345
Ensembl chr  X:153,996,128...153,999,445 		JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 decreases expression EXP senecionine results in decreased expression of SCD1 protein CTD PMID:35357534 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318 		JBrowse link
G Sdc2 syndecan 2 decreases expression EXP senecionine results in decreased expression of SDC2 protein CTD PMID:35357534 NCBI chr15:32,920,869...33,034,867
Ensembl chr15:32,920,869...33,035,081 		JBrowse link
G Sdc4 syndecan 4 decreases expression EXP senecionine results in decreased expression of SDC4 protein CTD PMID:35357534 NCBI chr 2:164,266,167...164,285,512
Ensembl chr 2:164,266,167...164,285,807 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression EXP senecionine results in increased expression of SDR42E1 protein CTD PMID:35357534 NCBI chr 8:118,388,138...118,400,428
Ensembl chr 8:118,388,138...118,400,428 		JBrowse link
G Secisbp2l SECIS binding protein 2-like decreases expression EXP senecionine results in decreased expression of SECISBP2L protein CTD PMID:35357534 NCBI chr 2:125,578,906...125,624,790
Ensembl chr 2:125,578,906...125,624,790 		JBrowse link
G Sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E decreases expression EXP senecionine results in decreased expression of SEMA3E protein CTD PMID:35357534 NCBI chr 5:14,075,290...14,306,703
Ensembl chr 5:14,075,290...14,306,703 		JBrowse link
G Sema4b sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B decreases expression EXP senecionine results in decreased expression of SEMA4B protein CTD PMID:35357534 NCBI chr 7:79,836,618...79,876,394
Ensembl chr 7:79,836,589...79,876,275 		JBrowse link
G Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 decreases expression EXP senecionine results in decreased expression of SERPINA10 protein CTD PMID:35357534 NCBI chr12:103,582,934...103,597,681
Ensembl chr12:103,581,045...103,597,703 		JBrowse link
G Serpina3m serine (or cysteine) peptidase inhibitor, clade A, member 3M decreases expression EXP senecionine results in decreased expression of SERPINA3M protein CTD PMID:35357534 NCBI chr12:104,353,424...104,360,518
Ensembl chr12:104,304,745...104,360,516 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N decreases expression EXP senecionine results in decreased expression of SERPINA3N protein CTD PMID:35357534 NCBI chr12:104,372,967...104,380,588
Ensembl chr12:104,372,988...104,380,588 		JBrowse link
G Serpina7 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 increases expression EXP senecionine results in increased expression of SERPINA7 protein CTD PMID:35357534 NCBI chr  X:137,979,998...137,985,985
Ensembl chr  X:137,980,006...137,985,985 		JBrowse link
G Sft2d3 SFT2 domain containing 3 increases expression EXP senecionine results in increased expression of SFT2D3 protein CTD PMID:35357534 NCBI chr18:32,042,147...32,044,956
Ensembl chr18:32,042,151...32,044,877 		JBrowse link
G Sgcb sarcoglycan, beta (dystrophin-associated glycoprotein) increases expression ISO senecionine results in increased expression of SGCB mRNA CTD PMID:32419051 NCBI chr 5:73,790,092...73,805,080
Ensembl chr 5:73,790,092...73,805,133 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 (BTK-associated) decreases expression EXP senecionine results in decreased expression of SH3BP5 protein CTD PMID:35357534 NCBI chr14:31,094,571...31,158,056
Ensembl chr14:31,081,837...31,158,035 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A decreases expression EXP senecionine results in decreased expression of SH3PXD2A protein CTD PMID:35357534 NCBI chr19:47,248,613...47,453,053
Ensembl chr19:47,248,613...47,452,840 		JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression ISO
EXP		 senecionine results in decreased expression of SLC10A1 mRNA CTD PMID:24641316 PMID:31606820 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479 		JBrowse link
G Slc16a12 solute carrier family 16 (monocarboxylic acid transporters), member 12 decreases expression EXP senecionine results in decreased expression of SLC16A12 protein CTD PMID:35357534 NCBI chr19:34,645,801...34,725,223
Ensembl chr19:34,645,803...34,724,689 		JBrowse link
G Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 increases expression EXP senecionine results in increased expression of SLC16A2 protein CTD PMID:35357534 NCBI chr  X:102,741,020...102,865,594
Ensembl chr  X:102,741,020...102,865,589 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 decreases expression EXP senecionine results in decreased expression of SLC22A1 mRNA CTD PMID:31606820 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 decreases expression ISO senecionine results in decreased expression of SLC22A9 mRNA CTD PMID:26100227 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675 		JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 decreases expression ISO
EXP		 senecionine results in decreased expression of SLC22A7 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383 		JBrowse link
G Slc25a47 solute carrier family 25, member 47 increases expression EXP senecionine results in increased expression of SLC25A47 protein CTD PMID:35357534 NCBI chr12:108,815,740...108,822,741
Ensembl chr12:108,801,972...108,822,741 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 increases expression EXP senecionine results in increased expression of SLC2A3 protein CTD PMID:35357534 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression EXP senecionine results in decreased expression of SLC30A10 protein CTD PMID:35357534 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
G Slc31a2 solute carrier family 31, member 2 decreases expression EXP senecionine results in decreased expression of SLC31A2 protein CTD PMID:35357534 NCBI chr 4:62,198,630...62,216,649
Ensembl chr 4:62,180,799...62,216,648 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression EXP senecionine results in decreased expression of SLC38A4 protein CTD PMID:35357534 NCBI chr15:96,892,701...96,953,837
Ensembl chr15:96,892,701...96,953,837 		JBrowse link
G Slc39a14 solute carrier family 39 (zinc transporter), member 14 decreases expression EXP senecionine results in decreased expression of SLC39A14 protein CTD PMID:35357534 NCBI chr14:70,540,916...70,588,873
Ensembl chr14:70,540,918...70,588,874 		JBrowse link
G Slc3a1 solute carrier family 3, member 1 decreases expression EXP senecionine results in decreased expression of SLC3A1 protein CTD PMID:35357534 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664 		JBrowse link
G Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 decreases expression EXP senecionine results in decreased expression of SLC6A12 protein CTD PMID:35357534 NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression ISO senecionine results in decreased expression of SLCO1A2 mRNA CTD PMID:24641316 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 decreases expression ISO
EXP		 senecionine results in decreased expression of SLCO1B2 mRNA
senecionine results in decreased expression of SLCO1B3 mRNA		 CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression ISO senecionine results in increased expression of SMC2 mRNA CTD PMID:32419051 NCBI chr 4:52,438,966...52,488,365
Ensembl chr 4:52,439,243...52,488,260 		JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression ISO senecionine results in increased expression of SMC4 mRNA CTD PMID:32419051 NCBI chr 3:68,912,071...68,941,956
Ensembl chr 3:68,912,071...68,941,956 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 decreases expression EXP senecionine results in decreased expression of SMC6 protein CTD PMID:35357534 NCBI chr12:11,315,887...11,369,786
Ensembl chr12:11,315,887...11,369,786 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 decreases expression EXP senecionine results in decreased expression of SMOC1 protein CTD PMID:35357534 NCBI chr12:81,073,582...81,233,188
Ensembl chr12:81,073,582...81,233,188 		JBrowse link
G Smpx small muscle protein, X-linked decreases expression ISO senecionine results in decreased expression of SMPX mRNA CTD PMID:34185104 NCBI chr  X:156,481,969...156,535,587
Ensembl chr  X:156,481,906...156,535,587 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression EXP senecionine results in decreased expression of SND1 protein CTD PMID:35357534 NCBI chr 6:28,480,332...28,935,161
Ensembl chr 6:28,475,138...28,935,161 		JBrowse link
G Soat1 sterol O-acyltransferase 1 decreases expression EXP senecionine results in decreased expression of SOAT1 protein CTD PMID:35357534 NCBI chr 1:156,255,678...156,301,898
Ensembl chr 1:156,252,095...156,301,901 		JBrowse link
G Sqle squalene epoxidase decreases expression EXP senecionine results in decreased expression of SQLE protein CTD PMID:35357534 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP senecionine results in decreased expression of SREBF1 protein CTD PMID:35357534 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Sri sorcin increases expression EXP senecionine results in increased expression of SRI protein CTD PMID:35357534 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379 		JBrowse link
G Srl sarcalumenin decreases expression ISO senecionine results in decreased expression of SRL mRNA CTD PMID:34185104 NCBI chr16:4,294,843...4,359,772
Ensembl chr16:4,298,080...4,359,680 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression ISO senecionine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr10:127,337,505...127,344,692
Ensembl chr10:127,337,555...127,344,692 		JBrowse link
G Stc1 stanniocalcin 1 increases expression ISO senecionine results in increased expression of STC1 mRNA CTD PMID:34185104 NCBI chr14:69,266,738...69,278,850
Ensembl chr14:69,266,687...69,279,253 		JBrowse link
G Steap4 STEAP family member 4 increases expression
decreases expression		 ISO
EXP		 senecionine results in increased expression of STEAP4 mRNA
senecionine results in decreased expression of STEAP4 protein		 CTD PMID:34185104 PMID:35357534 NCBI chr 5:8,010,472...8,032,213
Ensembl chr 5:8,010,457...8,032,213 		JBrowse link
G Stil Scl/Tal1 interrupting locus increases expression ISO senecionine results in increased expression of STIL mRNA CTD PMID:32419051 NCBI chr 4:114,857,287...114,900,404
Ensembl chr 4:114,857,356...114,900,393 		JBrowse link
G Stmn1 stathmin 1 increases expression ISO senecionine results in increased expression of STMN1 mRNA CTD PMID:32419051 NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154 		JBrowse link
G Ston1 stonin 1 increases expression EXP senecionine results in increased expression of STON1 protein CTD PMID:35357534 NCBI chr17:88,905,043...88,955,293
Ensembl chr17:88,905,112...88,970,014 		JBrowse link
G Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit increases expression EXP senecionine results in increased expression of SUCLG2 protein CTD PMID:35357534 NCBI chr 6:95,449,992...95,695,799
Ensembl chr 6:95,449,990...95,695,781 		JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 decreases expression ISO senecionine results in decreased expression of SULT1E1 mRNA CTD PMID:26100227 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453 		JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 decreases expression EXP senecionine results in decreased expression of SULT2A1 mRNA CTD PMID:31606820 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334 		JBrowse link
G Sult5a1 sulfotransferase family 5A, member 1 increases expression EXP senecionine results in increased expression of SULT1A1 protein CTD PMID:35357534 NCBI chr 8:123,869,582...123,885,170
Ensembl chr 8:123,866,931...123,885,054 		JBrowse link
G Surf2 surfeit gene 2 increases expression EXP senecionine results in increased expression of SURF2 protein CTD PMID:35357534 NCBI chr 2:26,806,420...26,810,199
Ensembl chr 2:26,806,379...26,810,195 		JBrowse link
G Syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae) decreases expression EXP senecionine results in decreased expression of SYF2 protein CTD PMID:35357534 NCBI chr 4:134,658,291...134,664,848
Ensembl chr 4:134,658,209...134,664,859 		JBrowse link
G Tcf19 transcription factor 19 increases expression ISO senecionine results in increased expression of TCF19 mRNA CTD PMID:32419051 NCBI chr17:35,823,627...35,827,730
Ensembl chr17:35,823,631...35,827,721 		JBrowse link
G Tdrd1 tudor domain containing 1 increases expression EXP senecionine results in increased expression of TDRD1 protein CTD PMID:35357534 NCBI chr19:56,814,603...56,858,444
Ensembl chr19:56,814,641...56,858,444 		JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 increases expression EXP senecionine results in increased expression of TECPR1 protein CTD PMID:35357534 NCBI chr 5:144,131,260...144,160,433
Ensembl chr 5:144,131,260...144,160,433 		JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO senecionine results in decreased expression of TENM1 mRNA CTD PMID:26100227 NCBI chr  X:41,616,743...42,518,045
Ensembl chr  X:41,616,743...42,518,003 		JBrowse link
G Tenm2 teneurin transmembrane protein 2 decreases expression ISO senecionine results in decreased expression of TENM2 mRNA CTD PMID:26100227 NCBI chr11:35,897,483...37,881,486
Ensembl chr11:35,897,483...37,126,791 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP senecionine results in increased expression of TGFB1 mRNA; senecionine results in increased expression of TGFB1 protein CTD PMID:35357534 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions		 ISO
EXP		 senecionine results in increased expression of THBS1 mRNA; senecionine results in increased expression of THBS1 protein
senecionine promotes the reaction [Pyrrolizidine Alkaloids binds to THBS1 protein]
Leu-Ser-Lys-Leu peptide inhibits the reaction [senecionine results in increased expression of THBS1 mRNA]; senecionine promotes the reaction [Pyrrolizidine Alkaloids binds to THBS1 protein]		 CTD PMID:35357534 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Tlr8 toll-like receptor 8 increases expression ISO senecionine results in increased expression of TLR8 mRNA CTD PMID:34185104 NCBI chr  X:166,024,119...166,047,325
Ensembl chr  X:166,025,692...166,047,325 		JBrowse link
G Tma7 translational machinery associated 7 decreases expression EXP senecionine results in decreased expression of TMA7 protein CTD PMID:35357534 NCBI chr 9:108,907,056...108,911,449
Ensembl chr 9:108,903,636...108,911,655 		JBrowse link
G Tmem144 transmembrane protein 144 increases expression EXP senecionine results in increased expression of TMEM144 protein CTD PMID:35357534 NCBI chr 3:79,719,871...79,760,093
Ensembl chr 3:79,719,871...79,760,080 		JBrowse link
G Tmem176a transmembrane protein 176A decreases expression EXP senecionine results in decreased expression of TMEM176A protein CTD PMID:35357534 NCBI chr 6:48,818,417...48,822,298
Ensembl chr 6:48,817,853...48,824,005 		JBrowse link
G Tmem176b transmembrane protein 176B decreases expression EXP senecionine results in decreased expression of TMEM176B protein CTD PMID:35357534 NCBI chr 6:48,810,745...48,818,363
Ensembl chr 6:48,810,752...48,818,430 		JBrowse link
G Tmem208 transmembrane protein 208 decreases expression EXP senecionine results in decreased expression of TMEM208 protein CTD PMID:35357534 NCBI chr 8:106,052,980...106,062,117
Ensembl chr 8:106,052,986...106,061,851 		JBrowse link
G Tmem35b transmembrane protein 35B increases expression EXP senecionine results in increased expression of TMEM35B protein CTD PMID:35357534 NCBI chr 4:127,019,836...127,023,453
Ensembl chr 4:127,017,484...127,023,437 		JBrowse link
G Tmem87b transmembrane protein 87B decreases expression EXP senecionine results in decreased expression of TMEM87B protein CTD PMID:35357534 NCBI chr 2:128,659,991...128,696,181
Ensembl chr 2:128,660,038...128,696,181 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b increases expression ISO senecionine results in increased expression of TNFRSF1B mRNA CTD PMID:34185104 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 decreases expression EXP senecionine results in decreased expression of TNIP2 protein CTD PMID:35357534 NCBI chr 5:34,653,440...34,671,323
Ensembl chr 5:34,653,431...34,671,335 		JBrowse link
G Tnnc1 troponin C, cardiac/slow skeletal decreases expression ISO senecionine results in decreased expression of TNNC1 mRNA CTD PMID:34185104 NCBI chr14:30,930,274...30,933,671
Ensembl chr14:30,930,269...30,933,686 		JBrowse link
G Top2a topoisomerase (DNA) II alpha increases expression ISO senecionine results in increased expression of TOP2A mRNA CTD PMID:32419051 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015 		JBrowse link
G Topors topoisomerase I binding, arginine/serine-rich decreases expression EXP senecionine results in decreased expression of TOPORS protein CTD PMID:35357534 NCBI chr 4:40,259,606...40,269,841
Ensembl chr 4:40,259,601...40,269,850 		JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression EXP senecionine results in decreased expression of TOX protein CTD PMID:35357534 NCBI chr 4:6,686,353...6,991,557
Ensembl chr 4:6,686,353...6,991,557 		JBrowse link
G Tpmt thiopurine methyltransferase increases expression ISO senecionine results in increased expression of TPMT mRNA CTD PMID:26100227 NCBI chr13:47,175,463...47,196,833
Ensembl chr13:47,175,958...47,198,213 		JBrowse link
G Tpx2 TPX2, microtubule-associated increases expression ISO senecionine results in increased expression of TPX2 mRNA CTD PMID:32419051 NCBI chr 2:152,689,859...152,737,241
Ensembl chr 2:152,689,884...152,737,241 		JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 increases expression EXP senecionine results in increased expression of TREML1 protein CTD PMID:35357534 NCBI chr17:48,666,944...48,674,204
Ensembl chr17:48,666,944...48,674,204 		JBrowse link
G Trp53 transformation related protein 53 increases expression ISO
EXP		 senecionine results in increased expression of TP53 mRNA
senecionine results in increased expression of TRP53 mRNA; senecionine results in increased expression of TRP53 protein		 CTD PMID:35357534 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699 		JBrowse link
G Tsr2 TSR2 20S rRNA accumulation decreases expression EXP senecionine results in decreased expression of TSR2 protein CTD PMID:35357534 NCBI chr  X:149,870,090...149,879,539
Ensembl chr  X:149,870,090...149,879,539 		JBrowse link
G Tstd3 thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 increases expression EXP senecionine results in increased expression of TSTD3 protein CTD PMID:35357534 NCBI chr 4:21,757,382...21,767,211
Ensembl chr 4:21,757,382...21,767,212 		JBrowse link
G Ttk Ttk protein kinase increases expression ISO senecionine results in increased expression of TTK mRNA CTD PMID:32419051 NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442 		JBrowse link
G Ttr transthyretin decreases expression EXP senecionine results in decreased expression of TTR protein CTD PMID:35357534 NCBI chr18:20,797,266...20,807,383
Ensembl chr18:20,798,337...20,807,378 		JBrowse link
G Tuft1 tuftelin 1 increases expression EXP senecionine results in increased expression of TUFT1 protein CTD PMID:35357534 NCBI chr 3:94,520,060...94,566,179
Ensembl chr 3:94,520,064...94,566,179 		JBrowse link
G Tyms thymidylate synthase increases expression ISO senecionine results in increased expression of TYMS mRNA CTD PMID:32419051 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615 		JBrowse link
G Ubl3 ubiquitin-like 3 decreases expression EXP senecionine results in decreased expression of UBL3 protein CTD PMID:35357534 NCBI chr 5:148,441,441...148,489,689
Ensembl chr 5:148,441,445...148,489,599 		JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) increases expression ISO senecionine results in increased expression of UCHL3 mRNA CTD PMID:26100227 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 increases expression EXP senecionine results in increased expression of UCKL1 protein CTD PMID:35357534 NCBI chr 2:181,210,942...181,223,820
Ensembl chr 2:181,210,942...181,226,685 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases glycosylation
multiple interactions		 ISO UGT1A4 protein results in increased glycosylation of senecionine
[hecogenin results in decreased activity of UGT1A4 protein] which results in decreased glycosylation of senecionine		 CTD PMID:20092275 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 decreases expression ISO senecionine results in decreased expression of UGT2A3 mRNA CTD PMID:26100227 NCBI chr 5:87,472,694...87,485,054
Ensembl chr 5:87,472,831...87,485,054 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression EXP senecionine results in decreased expression of UGT2B1 mRNA CTD PMID:31606820 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
G Utp11 UTP11 small subunit processome component decreases expression EXP senecionine results in decreased expression of UTP11 protein CTD PMID:35357534 NCBI chr 4:124,571,173...124,587,395
Ensembl chr 4:124,571,953...124,587,393 		JBrowse link
G Vps13b vacuolar protein sorting 13B decreases expression ISO senecionine results in decreased expression of VPS13B mRNA CTD PMID:26100227 NCBI chr15:35,371,264...35,931,375
Ensembl chr15:35,371,306...35,931,375 		JBrowse link
G Vps36 vacuolar protein sorting 36 increases expression EXP senecionine results in increased expression of VPS36 protein CTD PMID:35357534 NCBI chr 8:22,682,849...22,710,969
Ensembl chr 8:22,682,825...22,710,859 		JBrowse link
G Wdr53 WD repeat domain 53 decreases expression EXP senecionine results in decreased expression of WDR53 protein CTD PMID:35357534 NCBI chr16:32,066,047...32,075,901
Ensembl chr16:32,066,045...32,075,901 		JBrowse link
G Wdr82 WD repeat domain containing 82 decreases expression EXP senecionine results in decreased expression of WDR82 protein CTD PMID:35357534 NCBI chr 9:106,048,098...106,068,905
Ensembl chr 9:106,048,127...106,068,338 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A increases expression EXP senecionine results in increased expression of XPA protein CTD PMID:35357534 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
G Xylt2 xylosyltransferase II decreases expression EXP senecionine results in decreased expression of XYLT2 protein CTD PMID:35357534 NCBI chr11:94,554,671...94,568,341
Ensembl chr11:94,554,677...94,568,341 		JBrowse link
G Yipf5 Yip1 domain family, member 5 decreases expression EXP senecionine results in decreased expression of YIPF5 protein CTD PMID:35357534 NCBI chr18:40,337,918...40,352,452
Ensembl chr18:40,336,949...40,352,482 		JBrowse link
G Zcchc10 zinc finger, CCHC domain containing 10 increases expression EXP senecionine results in increased expression of ZCCHC10 protein CTD PMID:35357534 NCBI chr11:53,215,516...53,224,128
Ensembl chr11:53,215,506...53,224,128 		JBrowse link
G Zfp106 zinc finger protein 106 increases expression EXP senecionine results in increased expression of ZNF106 protein CTD PMID:35357534 NCBI chr 2:120,337,303...120,394,345
Ensembl chr 2:120,337,301...120,394,324 		JBrowse link
G Zfp367 zinc finger protein 367 increases expression ISO senecionine results in increased expression of ZFP367 mRNA CTD PMID:32419051 NCBI chr13:64,280,836...64,301,013
Ensembl chr13:64,280,832...64,301,016 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 increases expression EXP senecionine results in increased expression of ZFP36L1 protein CTD PMID:35357534 NCBI chr12:80,154,534...80,159,787
Ensembl chr12:80,154,528...80,159,787 		JBrowse link
G Zg16 zymogen granule protein 16 decreases expression EXP senecionine results in decreased expression of ZG16 protein CTD PMID:35357534 NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500 		JBrowse link
G Zwilch zwilch kinetochore protein increases expression ISO senecionine results in increased expression of ZWILCH mRNA CTD PMID:32419051 NCBI chr 9:64,044,426...64,080,210
Ensembl chr 9:64,044,426...64,080,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      biological role 22162
        biochemical role 21431
          metabolite 21379
            alkaloid 7888
              pyrrolizidine alkaloid 784
                senecionine 525
                  dehydrojacoline 0
                  jacoline + 0
                  senecionine N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                organic heterocyclic compound 20352
                                  organic heteropolycyclic compound 19645
                                    organic heterobicyclic compound 18203
                                      pyrrolizines 836
                                        pyrrolizine alkaloid 635
                                          senecionan 635
                                            senecionine 525
                                              dehydrojacoline 0
                                              jacoline + 0
                                              senecionine N-oxide 0
paths to the root