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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:senecionine
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Accession:CHEBI:9107 term browser browse the term
Definition:A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio.
Synonyms:exact_synonym: 12-hydroxysenecionan-11,16-dione
 related_synonym: Formula=C18H25NO5;   InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4-/t11-,14-,15-,18-/m1/s1;   InChIKey=HKODIGSRFALUTA-JTLQZVBZSA-N;   SMILES=[H]\\C(C)=C1/C[C@@H](C)[C@@](C)(O)C(=O)OCC2=CCN3CC[C@@]([H])(OC1=O)[C@@]23[H];   Senecionin;   aureine
 xref: Beilstein:8162955;   Beilstein:934445;   Beilstein:94450;   CAS:130-01-8;   KEGG:C06176;   KNApSAcK:C00002116
 xref_mesh: MESH:C009237
 xref: PMID:15202562;   PMID:17260281;   PMID:21710732;   Reaxys:94450
 cyclic_relationship: is_conjugate_base_of CHEBI:77617


show annotations for term's descendants           Sort by:
senecionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 decreases expression ISO senecionine results in decreased expression of ABCA3 protein CTD PMID:35357534 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO senecionine results in decreased expression of ABCB11 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO senecionine results in decreased expression of ABCB1 mRNA CTD PMID:31606820 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression EXP senecionine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO senecionine results in decreased expression of ABCB4 mRNA CTD PMID:31606820 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO senecionine results in increased expression of ABCC1 mRNA CTD PMID:31606820 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO senecionine results in decreased expression of ABCC2 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression		 EXP
ISO		 senecionine results in increased expression of ABCC3 mRNA
senecionine results in decreased expression of ABCC3 mRNA		 CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO senecionine results in decreased expression of ABCC4 mRNA CTD PMID:31606820 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO senecionine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abhd11 abhydrolase domain containing 11 increases expression ISO senecionine results in increased expression of ABHD11 protein CTD PMID:35357534 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO senecionine results in increased expression of ABTB2 protein CTD PMID:35357534 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression ISO senecionine results in increased expression of ACAA1A protein CTD PMID:35357534 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO senecionine results in increased expression of ACAA1B protein CTD PMID:35357534 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 increases expression ISO senecionine results in increased expression of ACOT13 protein CTD PMID:35357534 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO senecionine results in increased expression of ACOT2 protein CTD PMID:35357534 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO senecionine results in increased expression of ACOT3 protein CTD PMID:35357534 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 increases expression ISO senecionine results in increased expression of ACOT4 protein CTD PMID:35357534 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSL3 mRNA CTD PMID:26100227 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression ISO senecionine results in decreased expression of ACSL4 protein CTD PMID:35357534 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSM3 mRNA CTD PMID:26100227 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184 		JBrowse link
G Acss3 acyl-CoA synthetase short-chain family member 3 increases expression ISO senecionine results in increased expression of ACSS3 protein CTD PMID:35357534 NCBI chr 7:42,241,261...42,450,209
Ensembl chr 7:42,242,652...42,450,230 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP senecionine results in decreased expression of ACTG2 mRNA CTD PMID:34185104 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP senecionine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide increases expression ISO senecionine results in increased expression of ADH1 protein CTD PMID:35357534 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Aff3 ALF transcription elongation factor 3 decreases expression ISO senecionine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase decreases expression ISO senecionine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression ISO senecionine results in decreased expression of AIF1 protein CTD PMID:35357534 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO senecionine results in increased expression of AKAP12 protein CTD PMID:35357534 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP senecionine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 increases expression ISO senecionine results in increased expression of ALDH1B1 protein CTD PMID:35357534 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO senecionine results in increased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO senecionine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 increases expression ISO senecionine results in increased expression of ANAPC2 protein CTD PMID:35357534 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression EXP senecionine results in decreased expression of ANKRD1 mRNA CTD PMID:34185104 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Anxa1 annexin A1 increases expression ISO senecionine results in increased expression of ANXA1 protein CTD PMID:35357534 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apcs amyloid P component, serum decreases expression ISO senecionine results in decreased expression of APCS protein CTD PMID:35357534 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Apob apolipoprotein B decreases expression ISO senecionine results in decreased expression of APOB protein CTD PMID:35357534 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO senecionine results in decreased expression of APOC1 protein CTD PMID:35357534 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Apoh apolipoprotein H decreases expression ISO senecionine results in decreased expression of APOH protein CTD PMID:35357534 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Apom apolipoprotein M decreases expression ISO senecionine results in decreased expression of APOM protein CTD PMID:35357534 NCBI chr20:3,690,950...3,693,550
Ensembl chr20:3,688,413...3,693,550 		JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO senecionine results in decreased expression of AQP4 protein CTD PMID:35357534 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp8 aquaporin 8 increases expression ISO senecionine results in increased expression of AQP8 protein CTD PMID:35357534 NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158 		JBrowse link
G Areg amphiregulin increases expression ISO senecionine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression EXP senecionine results in increased expression of ARHGAP11A mRNA CTD PMID:32419051 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559 		JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 decreases expression ISO senecionine results in decreased expression of ARL6IP1 protein CTD PMID:35357534 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994 		JBrowse link
G Arl6ip4 ADP-ribosylation factor like GTPase 6 interacting protein 4 decreases expression ISO senecionine results in decreased expression of ARL6IP4 protein CTD PMID:35357534 NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression EXP senecionine results in increased expression of ATAD2 mRNA CTD PMID:32419051 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO senecionine results in increased expression of ATF3 protein CTD PMID:35357534 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp13a2 ATPase cation transporting 13A2 decreases expression ISO senecionine results in decreased expression of ATP13A2 protein CTD PMID:35357534 NCBI chr 5:153,292,722...153,312,143
Ensembl chr 5:153,292,751...153,312,139 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO senecionine results in increased expression of ATP2A3 protein CTD PMID:35357534 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 decreases expression ISO senecionine results in decreased expression of ATP5IF1 protein CTD PMID:35357534 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H increases expression ISO senecionine results in increased expression of ATP6V1H protein CTD PMID:35357534 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 increases expression ISO senecionine results in increased expression of ATPAF2 protein CTD PMID:35357534 NCBI chr10:45,205,658...45,221,891
Ensembl chr10:45,197,441...45,221,026 		JBrowse link
G Axin2 axin 2 decreases expression ISO senecionine results in decreased expression of AXIN2 mRNA CTD PMID:31606820 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G B3galt1 Beta-1,3-galactosyltransferase 1 decreases expression ISO senecionine results in decreased expression of B3GALT1 protein CTD PMID:35357534 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression EXP
ISO		 senecionine results in decreased expression of BAAT mRNA CTD PMID:24641316 PMID:26100227 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO senecionine results in decreased expression of BCL2L1 protein CTD PMID:29458164 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO senecionine results in increased expression of BCL3 protein CTD PMID:35357534 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO senecionine results in decreased expression of BNIP3 protein CTD PMID:35357534 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bod1l1 biorientation of chromosomes in cell division 1-like 1 decreases expression ISO senecionine results in decreased expression of BOD1L protein CTD PMID:35357534 NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490 		JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO senecionine results in increased expression of BPGM protein CTD PMID:35357534 NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581 		JBrowse link
G Btc betacellulin increases expression ISO senecionine results in increased expression of BTC protein CTD PMID:35357534 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049 		JBrowse link
G C3 complement C3 decreases expression ISO senecionine results in decreased expression of C3 protein CTD PMID:35357534 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C3ar1 complement C3a receptor 1 increases expression EXP senecionine results in increased expression of C3AR1 mRNA CTD PMID:34185104 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C4b complement C4B decreases expression ISO senecionine results in decreased expression of C4B protein CTD PMID:35357534 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G C5 complement C5 decreases expression ISO senecionine results in decreased expression of C5 protein CTD PMID:35357534 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression ISO senecionine results in increased expression of CAMP protein CTD PMID:35357534 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Car1 carbonic anhydrase 1 increases expression ISO senecionine results in increased expression of CA1 protein CTD PMID:35357534 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO senecionine results in increased expression of CA2 protein CTD PMID:35357534 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car5a carbonic anhydrase 5A increases expression ISO senecionine results in increased expression of CA5A protein CTD PMID:35357534 NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906 		JBrowse link
G Car5b carbonic anhydrase 5B increases expression ISO senecionine results in increased expression of CA5B protein CTD PMID:35357534 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837 		JBrowse link
G Casp12 caspase 12 increases expression EXP senecionine results in increased expression of CASP12 mRNA CTD PMID:32419051 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity ISO senecionine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cav1 caveolin 1 decreases expression ISO senecionine results in decreased expression of CAV1 protein CTD PMID:35357534 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cavin3 caveolae associated protein 3 decreases expression ISO senecionine results in decreased expression of CAVIN3 protein CTD PMID:35357534 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161 		JBrowse link
G Ccdc137 coiled-coil domain containing 137 decreases expression ISO senecionine results in decreased expression of CCDC137 protein CTD PMID:35357534 NCBI chr10:105,730,776...105,737,158
Ensembl chr10:105,730,739...105,737,158 		JBrowse link
G Ccna2 cyclin A2 increases expression EXP senecionine results in increased expression of CCNA2 mRNA CTD PMID:32419051 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccne2 cyclin E2 increases expression EXP senecionine results in increased expression of CCNE2 mRNA CTD PMID:32419051 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP senecionine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccpg1 cell cycle progression 1 decreases expression ISO senecionine results in decreased expression of CCPG1 protein CTD PMID:35357534 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430 		JBrowse link
G Cd163 CD163 molecule decreases expression ISO senecionine results in decreased expression of CD163 protein CTD PMID:35357534 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd177 CD177 molecule increases expression ISO senecionine results in increased expression of CD177 protein CTD PMID:35357534 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Cd300lg Cd300 molecule-like family member G decreases expression ISO senecionine results in decreased expression of CD300LG protein CTD PMID:35357534 NCBI chr10:86,991,886...87,009,248
Ensembl chr10:86,991,921...87,008,733 		JBrowse link
G Cd47 Cd47 molecule increases expression ISO senecionine results in increased expression of CD47 mRNA; senecionine results in increased expression of CD47 protein CTD PMID:35357534 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cdadc1 cytidine and dCMP deaminase domain containing 1 decreases expression ISO senecionine results in decreased expression of CDADC1 protein CTD PMID:35357534 NCBI chr15:33,726,590...33,755,611
Ensembl chr15:33,723,435...33,755,576 		JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 decreases expression ISO senecionine results in decreased expression of CDKAL1 protein CTD PMID:35357534 NCBI chr17:34,718,701...35,271,276
Ensembl chr17:34,718,687...35,407,524 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP
ISO		 senecionine results in increased expression of CDKN1A mRNA
senecionine results in increased expression of CDKN1A protein		 CTD PMID:32419051 PMID:35357534 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cel carboxyl ester lipase decreases expression ISO senecionine results in decreased expression of CEL protein CTD PMID:35357534 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Cenpq centromere protein Q increases expression EXP senecionine results in increased expression of CENPQ mRNA CTD PMID:32419051 NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789 		JBrowse link
G Cenpw centromere protein W increases expression EXP senecionine results in increased expression of CENPW mRNA CTD PMID:32419051 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cep97 centrosomal protein 97 increases expression ISO senecionine results in increased expression of CEP97 protein CTD PMID:35357534 NCBI chr11:44,683,503...44,711,471
Ensembl chr11:44,683,506...44,711,471 		JBrowse link
G Cfh complement factor H decreases expression ISO senecionine results in decreased expression of CFH protein CTD PMID:35357534 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cgnl1 cingulin-like 1 decreases expression ISO senecionine results in decreased expression of CGNL1 protein CTD PMID:35357534 NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917 		JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 increases expression ISO senecionine results in increased expression of CHAMP1 protein CTD PMID:35357534 NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984 		JBrowse link
G Chtop chromatin target of PRMT1 decreases expression ISO senecionine results in decreased expression of CHTOP protein CTD PMID:35357534 NCBI chr 2:175,981,266...175,992,820
Ensembl chr 2:175,981,271...175,992,748 		JBrowse link
G Cib1 calcium and integrin binding 1 increases expression ISO senecionine results in increased expression of CIB1 protein CTD PMID:35357534 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Cir1 corepressor interacting with RBPJ, 1 decreases expression ISO senecionine results in decreased expression of CIR1 protein CTD PMID:35357534 NCBI chr 3:58,158,923...58,188,799
Ensembl chr 3:58,158,951...58,188,789 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP senecionine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 decreases expression ISO senecionine results in decreased expression of CKMT1 protein CTD PMID:35357534 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758 		JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP senecionine results in decreased expression of CKMT2 mRNA CTD PMID:34185104 NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430 		JBrowse link
G Clec3b C-type lectin domain family 3, member B decreases expression ISO senecionine results in decreased expression of CLEC3B protein CTD PMID:35357534 NCBI chr 8:122,810,120...122,815,837
Ensembl chr 8:122,810,149...122,815,835 		JBrowse link
G Clec4a1 C-type lectin domain family 4, member A1 increases expression EXP senecionine results in increased expression of CLEC4A1 mRNA CTD PMID:34185104 NCBI chr 4:156,173,894...156,186,009
Ensembl chr 4:156,173,894...156,186,008 		JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP
ISO		 senecionine results in decreased expression of CLEC4F mRNA
senecionine results in decreased expression of CLEC4F protein		 CTD PMID:32419051 PMID:35357534 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775 		JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein decreases expression ISO senecionine results in decreased expression of CNBP protein CTD PMID:35357534 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637 		JBrowse link
G Cntrl centriolin decreases expression ISO senecionine results in decreased expression of CNTRL protein CTD PMID:35357534 NCBI chr 3:18,428,147...18,500,362
Ensembl chr 3:18,428,103...18,500,380 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO senecionine results in decreased expression of COL18A1 protein CTD PMID:35357534 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Cops3 COP9 signalosome subunit 3 increases expression ISO senecionine results in increased expression of COPS3 protein CTD PMID:35357534 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
G Coro1a coronin 1A increases expression ISO senecionine results in increased expression of CORO1A protein CTD PMID:35357534 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534 		JBrowse link
G Cpa1 carboxypeptidase A1 decreases expression ISO senecionine results in decreased expression of CPA1 protein CTD PMID:35357534 NCBI chr 4:59,257,417...59,263,544
Ensembl chr 4:59,257,417...59,263,544 		JBrowse link
G Cpb2 carboxypeptidase B2 decreases expression ISO senecionine results in decreased expression of CPB2 protein CTD PMID:35357534 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 decreases expression ISO senecionine results in decreased expression of CRELD1 protein CTD PMID:35357534 NCBI chr 4:146,631,883...146,641,493
Ensembl chr 4:146,631,883...146,641,499 		JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 decreases expression ISO senecionine results in decreased expression of CRELD2 protein CTD PMID:35357534 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543 		JBrowse link
G Crip1 cysteine rich protein 1 decreases expression ISO senecionine results in decreased expression of CRIP1 protein CTD PMID:35357534 NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620 		JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP senecionine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 increases expression ISO senecionine results in increased expression of CTDNEP1 protein CTD PMID:35357534 NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781 		JBrowse link
G Ctrl chymotrypsin-like decreases expression ISO senecionine results in decreased expression of CTRB1 protein CTD PMID:35357534 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsg cathepsin G increases expression ISO senecionine results in increased expression of CTSG protein CTD PMID:35357534 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO senecionine results in decreased expression of CXCL12 protein CTD PMID:35357534 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO senecionine results in increased expression of CXCR4 mRNA CTD PMID:35357534 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP11A1 mRNA CTD PMID:26100227 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1A1 mRNA CTD PMID:26100227 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression		 ISO senecionine results in increased expression of CYP1A2 mRNA
senecionine results in decreased expression of CYP1A2 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1B1 mRNA CTD PMID:26100227 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP2A13 mRNA CTD PMID:26100227 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 increases expression ISO senecionine results in increased expression of CYP2A4 protein CTD PMID:35357534 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression
affects expression		 ISO senecionine results in increased expression of CYP2B6 mRNA
senecionine affects the expression of CYP2B10 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression ISO senecionine results in decreased expression of CYP2C18 mRNA CTD PMID:26100227 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
decreases expression		 ISO senecionine results in increased expression of CYP2E1 mRNA
senecionine results in decreased expression of CYP2E1 mRNA		 CTD PMID:26100227 PMID:31606820 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO senecionine results in increased expression of CYP3A43 mRNA CTD PMID:26100227 NCBI chr12:8,880,509...8,930,382
Ensembl chr12:8,880,528...8,930,381 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases response to substance		 ISO senecionine results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased susceptibility to senecionine		 CTD PMID:26100227 PMID:32910235 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO senecionine results in decreased expression of CYP3A5 mRNA CTD PMID:26100227 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO senecionine results in decreased expression of CYP4F12 mRNA CTD PMID:26100227 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 increases expression ISO senecionine results in increased expression of CYP4F11 mRNA CTD PMID:26100227 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP
ISO		 senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO senecionine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP senecionine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668 		JBrowse link
G Dbr1 debranching RNA lariats 1 increases expression ISO senecionine results in increased expression of DBR1 protein CTD PMID:35357534 NCBI chr 8:100,139,039...100,150,768
Ensembl chr 8:100,139,034...100,151,030 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression EXP senecionine results in increased expression of DDIAS mRNA CTD PMID:32419051 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Dedd death effector domain-containing decreases expression ISO senecionine results in decreased expression of DEDD protein CTD PMID:35357534 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332 		JBrowse link
G Dguok deoxyguanosine kinase increases expression ISO senecionine results in increased expression of DGUOK protein CTD PMID:35357534 NCBI chr 4:115,987,101...116,014,733
Ensembl chr 4:115,979,094...116,014,733 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO senecionine results in increased expression of DHRS2 mRNA CTD PMID:26100227 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO senecionine results in increased expression of DHRS9 mRNA CTD PMID:26100227 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Diaph3 diaphanous-related formin 3 increases expression EXP senecionine results in increased expression of DIAPH3 mRNA CTD PMID:32419051 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A decreases expression ISO senecionine results in decreased expression of DIP2A protein CTD PMID:35357534 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Dlgap5 DLG associated protein 5 increases expression EXP senecionine results in increased expression of DLGAP5 mRNA CTD PMID:32419051 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 decreases expression ISO senecionine results in decreased expression of DMBT1 protein CTD PMID:35357534 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO senecionine results in increased expression of DNAJB9 protein CTD PMID:35357534 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 decreases expression ISO senecionine results in decreased expression of DNAJC12 protein CTD PMID:35357534 NCBI chr20:25,246,744...25,267,508
Ensembl chr20:25,223,144...25,267,521 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression ISO senecionine results in decreased expression of DNAJC15 protein CTD PMID:35357534 NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675 		JBrowse link
G Dph5 diphthamide biosynthesis 5 increases expression ISO senecionine results in increased expression of DPH5 protein CTD PMID:35357534 NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression ISO senecionine results in decreased expression of DPYD mRNA CTD PMID:26100227 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression EXP senecionine results in increased expression of DTL mRNA CTD PMID:32419051 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO senecionine results in increased expression of DUSP1 protein CTD PMID:35357534 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dynll2 dynein light chain LC8-type 2 decreases expression ISO senecionine results in decreased expression of DYNLL2 protein CTD PMID:35357534 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805 		JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP senecionine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO senecionine results in decreased expression of EGFR protein CTD PMID:35357534 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G decreases expression ISO senecionine results in decreased expression of EIF3G protein CTD PMID:35357534 NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO senecionine results in decreased expression of EIF4B protein CTD PMID:35357534 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Elf1 E74 like ETS transcription factor 1 decreases expression ISO senecionine results in decreased expression of ELF1 protein CTD PMID:35357534 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 decreases expression ISO senecionine results in decreased expression of ELOVL1 protein CTD PMID:35357534 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G Emilin2 elastin microfibril interfacer 2 increases expression EXP senecionine results in increased expression of EMILIN2 mRNA CTD PMID:34185104 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352 		JBrowse link
G Eng endoglin decreases expression ISO senecionine results in decreased expression of ENG protein CTD PMID:35357534 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Eno3 enolase 3 increases expression ISO senecionine results in increased expression of ENO3 protein CTD PMID:35357534 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression ISO senecionine results in increased expression of ENTPD5 protein CTD PMID:35357534 NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530 		JBrowse link
G Epha2 Eph receptor A2 increases expression ISO senecionine results in increased expression of EPHA2 protein CTD PMID:35357534 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO senecionine results in decreased expression of EPHX2 mRNA CTD PMID:26100227 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Epm2a EPM2A glucan phosphatase, laforin increases expression ISO senecionine results in increased expression of EPM2A protein CTD PMID:35357534 NCBI chr 1:5,727,111...5,845,338
Ensembl chr 1:5,727,066...5,920,555 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO senecionine results in increased expression of ERP29 protein CTD PMID:35357534 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression EXP senecionine results in increased expression of ESCO2 mRNA CTD PMID:32419051 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Esrra estrogen related receptor, alpha decreases expression ISO senecionine results in decreased expression of ESRRA protein CTD PMID:35357534 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase decreases expression EXP senecionine results in decreased expression of ETHE1 mRNA CTD PMID:32419051 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052 		JBrowse link
G Etnppl ethanolamine-phosphate phospho-lyase increases expression ISO senecionine results in increased expression of ETNPPL protein CTD PMID:35357534 NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO senecionine results in increased expression of ETS2 protein CTD PMID:35357534 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319 		JBrowse link
G Etv6 ETS variant transcription factor 6 decreases expression ISO senecionine results in decreased expression of ETV6 protein CTD PMID:35357534 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 decreases expression ISO senecionine results in decreased expression of EXT1 protein CTD PMID:35357534 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G F13a1 coagulation factor XIII A1 chain increases expression ISO senecionine results in increased expression of F13A1 protein CTD PMID:35357534 NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G Fancd2 FA complementation group D2 increases expression EXP senecionine results in increased expression of FANCD2 mRNA CTD PMID:32419051 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO
EXP		 senecionine metabolite results in increased expression of FAS mRNA
senecionine results in increased expression of FAS mRNA		 CTD PMID:30465738 PMID:32419051 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fbxo21 F-box protein 21 increases expression ISO senecionine results in increased expression of FBXO21 protein CTD PMID:35357534 NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133 		JBrowse link
G Fcgr3a Fc gamma receptor 3A increases expression EXP senecionine results in increased expression of FCGR3A mRNA CTD PMID:34185104 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO senecionine results in decreased expression of FDFT1 protein CTD PMID:35357534 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fgl1 fibrinogen-like 1 decreases expression ISO senecionine results in decreased expression of FGL1 protein CTD PMID:35357534 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Fis1 fission, mitochondrial 1 decreases expression ISO senecionine results in decreased expression of FIS1 protein CTD PMID:35357534 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases expression ISO senecionine results in increased expression of FMO3 protein CTD PMID:35357534 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO senecionine results in decreased expression of FMO4 mRNA CTD PMID:26100227 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression ISO senecionine results in decreased expression of FMO5 mRNA CTD PMID:26100227 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 decreases expression ISO senecionine results in decreased expression of FMR1 protein CTD PMID:35357534 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B decreases expression ISO senecionine results in decreased expression of FNDC3B protein CTD PMID:35357534 NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830 		JBrowse link
G Folr2 folate receptor beta decreases expression ISO senecionine results in decreased expression of FOLR2 protein CTD PMID:35357534 NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724 		JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO senecionine results in decreased expression of FRMD4B protein CTD PMID:35357534 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197 		JBrowse link
G Ftsj3 FtsJ RNA 2'-O-methyltransferase 3 decreases expression ISO senecionine results in decreased expression of FTSJ3 protein CTD PMID:35357534 NCBI chr10:91,180,945...91,187,389
Ensembl chr10:91,180,696...91,187,397 		JBrowse link
G Fyb2 FYN binding protein 2 decreases expression ISO senecionine results in decreased expression of FYB2 protein CTD PMID:35357534 NCBI chr 5:119,677,116...119,800,911
Ensembl chr 5:119,677,204...119,800,910 		JBrowse link
G Fyttd1 forty-two-three domain containing 1 decreases expression ISO senecionine results in decreased expression of FYTTD1 protein CTD PMID:35357534 NCBI chr11:67,877,967...67,907,500
Ensembl chr11:67,877,967...67,907,511 		JBrowse link
G G0s2 G0/G1switch 2 increases expression ISO senecionine results in increased expression of G0S2 protein CTD PMID:35357534 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO senecionine results in increased expression of G6PDX protein CTD PMID:35357534 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gc GC, vitamin D binding protein decreases expression ISO senecionine results in decreased expression of GC protein CTD PMID:35357534 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gckr glucokinase regulator increases expression ISO senecionine results in increased expression of GCKR protein CTD PMID:35357534 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
G Gcsh glycine cleavage system protein H increases expression ISO senecionine results in increased expression of GCSH protein CTD PMID:35357534 NCBI chr19:45,036,013...45,046,770
Ensembl chr19:45,036,011...45,046,792 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO senecionine results in increased expression of GEM mRNA CTD PMID:26100227 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Ghr growth hormone receptor decreases expression ISO senecionine results in decreased expression of GHR protein CTD PMID:35357534 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gls glutaminase increases expression ISO senecionine results in increased expression of GLS mRNA CTD PMID:26100227 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Glyat glycine-N-acyltransferase decreases expression ISO senecionine results in decreased expression of GLYAT mRNA CTD PMID:26100227 NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942 		JBrowse link
G Gnmt glycine N-methyltransferase increases expression ISO senecionine results in increased expression of GNMT mRNA CTD PMID:26100227 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Gpatch4 G patch domain containing 4 increases expression ISO senecionine results in increased expression of GPATCH4 protein CTD PMID:35357534 NCBI chr 2:173,499,700...173,520,346
Ensembl chr 2:173,509,897...173,518,684 		JBrowse link
G Gpc1 glypican 1 decreases expression EXP senecionine results in decreased expression of GPC1 mRNA CTD PMID:34185104 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 increases expression ISO senecionine results in increased expression of GPCPD1 protein CTD PMID:35357534 NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517 		JBrowse link
G Gphn gephyrin decreases expression ISO senecionine results in decreased expression of GPHN mRNA CTD PMID:26100227 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A increases expression ISO senecionine results in increased expression of GPRC5A mRNA CTD PMID:26100227 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260 		JBrowse link
G Gpsm3 G-protein signaling modulator 3 increases expression ISO senecionine results in increased expression of GPSM3 protein CTD PMID:35357534 NCBI chr20:4,157,123...4,158,984
Ensembl chr20:4,157,123...4,159,035 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
increases expression		 EXP
ISO		 senecionine results in increased activity of GPT protein
POR protein affects the reaction [senecionine results in increased expression of GPT protein]		 CTD PMID:24641316 PMID:31606820 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP senecionine results in increased expression of GRIA3 mRNA CTD PMID:32419051 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grn granulin precursor decreases expression ISO senecionine results in decreased expression of GRN protein CTD PMID:35357534 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial increases expression ISO senecionine results in increased expression of GRPEL1 protein CTD PMID:35357534 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO senecionine results in decreased expression of GSTA4 mRNA CTD PMID:26100227 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression ISO senecionine results in decreased expression of GSTT1 mRNA CTD PMID:26100227 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gzma granzyme A decreases expression EXP senecionine results in decreased expression of GZMA mRNA CTD PMID:32419051 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO senecionine results in decreased expression of H1-4 protein CTD PMID:35357534 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO senecionine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Haus2 HAUS augmin like complex subunit 2 decreases expression ISO senecionine results in decreased expression of HAUS2 protein CTD PMID:35357534 NCBI chr 3:107,553,146...107,565,982
Ensembl chr 3:107,553,161...107,565,157 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases expression ISO senecionine results in increased expression of HBA protein CTD PMID:35357534 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta increases expression ISO senecionine results in increased expression of HBB-B1 protein CTD PMID:35357534 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hdlbp high density lipoprotein binding protein decreases expression ISO senecionine results in decreased expression of HDLBP protein CTD PMID:35357534 NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048 		JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 increases expression EXP senecionine results in increased expression of HERC6 mRNA CTD PMID:32419051 NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744 		JBrowse link
G Hic2 HIC ZBTB transcriptional repressor 2 decreases expression ISO senecionine results in decreased expression of HIC2 protein CTD PMID:35357534 NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO senecionine results in decreased expression of HMGCR protein CTD PMID:35357534 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression EXP senecionine results in increased expression of HMMR mRNA CTD PMID:32419051 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hnf1a HNF1 homeobox A decreases expression ISO senecionine results in decreased expression of HNF1A protein CTD PMID:35357534 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO senecionine results in decreased expression of HNMT mRNA CTD PMID:26100227 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 increases expression ISO senecionine results in increased expression of HOGA1 protein CTD PMID:35357534 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568 		JBrowse link
G Hp haptoglobin decreases expression ISO senecionine results in decreased expression of HP protein CTD PMID:35357534 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO senecionine results in increased expression of HSD3B1 protein CTD PMID:35357534 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO senecionine results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hypk Huntingtin interacting protein K decreases expression ISO senecionine results in decreased expression of HYPK protein CTD PMID:35357534 NCBI chr 3:108,434,997...108,436,370
Ensembl chr 3:108,432,539...108,436,370 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO senecionine results in increased expression of ICAM1 mRNA CTD PMID:35357534 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP senecionine results in increased expression of IFIT2 mRNA CTD PMID:32419051 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ift25 intraflagellar transport 25 increases expression ISO senecionine results in increased expression of IFT25 protein CTD PMID:35357534 NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO senecionine results in decreased expression of IGFBP4 protein CTD PMID:35357534 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 increases expression ISO senecionine results in increased expression of IGHG1 protein CTD PMID:35357534 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Il11 interleukin 11 increases expression ISO senecionine metabolite results in increased expression of IL11 mRNA CTD PMID:30465738 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 decreases expression ISO senecionine results in decreased expression of IL13RA1 protein CTD PMID:35357534 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP senecionine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO senecionine metabolite results in increased expression of IL1B mRNA CTD PMID:30465738 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer decreases expression ISO senecionine results in decreased expression of IL6ST protein CTD PMID:35357534 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression ISO senecionine results in increased expression of IMPDH2 protein CTD PMID:35357534 NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359 		JBrowse link
G Inip INTS3 and NABP interacting protein decreases expression ISO senecionine results in decreased expression of INIP protein CTD PMID:35357534 NCBI chr 5:74,648,392...74,662,628
Ensembl chr 5:74,648,392...74,662,628 		JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP senecionine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493 		JBrowse link
G Isca1 iron-sulfur cluster assembly 1 increases expression ISO senecionine results in increased expression of ISCA1 protein CTD PMID:35357534 NCBI chr17:4,905,291...4,917,955
Ensembl chr17:4,905,287...4,917,955 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO senecionine results in increased expression of ISG15 protein CTD PMID:35357534 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO senecionine results in increased expression of ISG20 mRNA CTD PMID:26100227 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO senecionine results in increased expression of ITGAM protein CTD PMID:35357534 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 decreases expression ISO senecionine results in decreased expression of ITIH2 protein CTD PMID:35357534 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO senecionine results in decreased expression of ITIH3 protein CTD PMID:35357534 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924 		JBrowse link
G Itm2b integral membrane protein 2B decreases expression ISO senecionine results in decreased expression of ITM2B protein CTD PMID:35357534 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917 		JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP senecionine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO senecionine results in decreased expression of JCHAIN protein CTD PMID:35357534 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO senecionine results in increased expression of JMJD6 protein CTD PMID:35357534 NCBI chr10:102,041,131...102,047,182
Ensembl chr10:102,041,120...102,047,182 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression ISO senecionine results in increased expression of JUNB protein CTD PMID:35357534 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kif11 kinesin family member 11 increases expression EXP senecionine results in increased expression of KIF11 mRNA CTD PMID:32419051 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif18a kinesin family member 18A increases expression EXP senecionine results in increased expression of KIF18A mRNA CTD PMID:32419051 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Knl1 kinetochore scaffold 1 increases expression EXP senecionine results in increased expression of KNL1 mRNA CTD PMID:32419051 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915 		JBrowse link
G Kntc1 kinetochore associated 1 increases expression EXP senecionine results in increased expression of KNTC1 mRNA CTD PMID:32419051 NCBI chr12:32,769,020...32,839,617
Ensembl chr12:32,769,020...32,839,561 		JBrowse link
G Krt19 keratin 19 decreases expression ISO senecionine results in decreased expression of KRT19 protein CTD PMID:35357534 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Ktn1 kinectin 1 decreases expression ISO senecionine results in decreased expression of KTN1 protein CTD PMID:35357534 NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO senecionine results in decreased expression of KYAT1 mRNA CTD PMID:26100227 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Larp4 La ribonucleoprotein 4 decreases expression ISO senecionine results in decreased expression of LARP4 protein CTD PMID:35357534 NCBI chr 7:131,104,470...131,152,692
Ensembl chr 7:131,101,564...131,150,811 		JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP senecionine results in increased expression of LBP mRNA CTD PMID:32419051 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO senecionine results in increased expression of LCN2 mRNA CTD PMID:31606820 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lgals2 galectin 2 decreases expression ISO senecionine results in decreased expression of LGALS2 protein CTD PMID:35357534 NCBI chr 7:110,403,171...110,410,046
Ensembl chr 7:110,403,173...110,404,802 		JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 decreases expression ISO senecionine results in decreased expression of LGR5 mRNA CTD PMID:31606820 NCBI chr 7:51,087,059...51,221,882
Ensembl chr 7:51,088,239...51,222,446 		JBrowse link
G Lin37 lin-37 DREAM MuvB core complex component decreases expression ISO senecionine results in decreased expression of LIN37 protein CTD PMID:35357534 NCBI chr 1:85,809,065...85,813,235
Ensembl chr 1:85,809,074...85,812,991 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO senecionine results in increased expression of LONP1 protein CTD PMID:35357534 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Lrp1 LDL receptor related protein 1 decreases expression ISO senecionine results in decreased expression of LRP1 protein CTD PMID:35357534 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 decreases expression ISO senecionine results in decreased expression of LRRC59 protein CTD PMID:35357534 NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533 		JBrowse link
G Ltf lactotransferrin increases expression ISO senecionine results in increased expression of LTF protein CTD PMID:35357534 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Lyz2 lysozyme 2 increases expression ISO senecionine results in increased expression of LYZ2 protein CTD PMID:35357534 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Maco1 macoilin 1 decreases expression ISO senecionine results in decreased expression of MACO1 protein CTD PMID:35357534 NCBI chr 5:147,012,416...147,075,265
Ensembl chr 5:147,012,867...147,075,001 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression EXP senecionine results in increased expression of MAD2L1 mRNA CTD PMID:32419051 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO senecionine results in increased expression of MAFF mRNA
senecionine results in increased expression of MAFF protein		 CTD PMID:26100227 PMID:35357534 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO senecionine results in increased expression of MAFK protein CTD PMID:35357534 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048 		JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP senecionine results in increased expression of MAL mRNA CTD PMID:34185104 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Maoa monoamine oxidase A decreases expression ISO senecionine results in decreased expression of MAOA mRNA CTD PMID:26100227 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO senecionine results in increased expression of MAP2K3 protein CTD PMID:35357534 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map7 microtubule-associated protein 7 decreases expression ISO senecionine results in decreased expression of MAP7 protein CTD PMID:35357534 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 decreases expression ISO senecionine results in decreased expression of MAPRE2 protein CTD PMID:35357534 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044 		JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression EXP senecionine results in increased expression of MASTL mRNA CTD PMID:32419051 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353 		JBrowse link
G Mbl2 mannose binding lectin 2 increases expression ISO senecionine results in increased expression of MBL2 protein CTD PMID:35357534 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression EXP senecionine results in increased expression of MCM3 mRNA CTD PMID:32419051 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression EXP senecionine results in increased expression of MCM5 mRNA CTD PMID:32419051 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mettl21a methyltransferase 21A, HSPA lysine increases expression ISO senecionine results in increased expression of METTL21A protein CTD PMID:35357534 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550 		JBrowse link
G Mgat5 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase decreases expression ISO senecionine results in decreased expression of MGAT5 protein CTD PMID:35357534 NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513 		JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 increases expression ISO senecionine results in increased expression of MGME1 protein CTD PMID:35357534 NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP senecionine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mib2 MIB E3 ubiquitin protein ligase 2 decreases expression ISO senecionine results in decreased expression of MIB2 protein CTD PMID:35357534 NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650 		JBrowse link
G Micos10 mitochondrial contact site and cristae organizing system subunit 10 decreases expression ISO senecionine results in decreased expression of MICOS10 protein CTD PMID:35357534 NCBI chr 5:151,341,124...151,367,403
Ensembl chr 5:151,339,176...151,367,485 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP senecionine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO senecionine results in increased expression of MMP1 mRNA CTD PMID:26100227 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions		 ISO senecionine results in increased expression of MMP9 mRNA
senecionine results in increased expression of MMP9 mRNA; senecionine results in increased expression of MMP9 protein
Leu-Ser-Lys-Leu peptide inhibits the reaction [senecionine results in increased expression of MMP9 mRNA]		 CTD PMID:35357534 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mmrn1 multimerin 1 increases expression ISO senecionine results in increased expression of MMRN1 protein CTD PMID:35357534 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474 		JBrowse link
G Mpdu1 mannose-P-dolichol utilization defect 1 decreases expression ISO senecionine results in decreased expression of MPDU1 protein CTD PMID:35357534 NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447 		JBrowse link
G Mpo myeloperoxidase increases expression ISO senecionine results in increased expression of MPO protein CTD PMID:35357534 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpst mercaptopyruvate sulfurtransferase increases expression ISO senecionine results in increased expression of MPST protein CTD PMID:35357534 NCBI chr 7:109,955,581...109,963,155
Ensembl chr 7:109,955,675...109,963,141 		JBrowse link
G Mrpl42 mitochondrial ribosomal protein L42 increases expression ISO senecionine results in increased expression of MRPL42 protein CTD PMID:35357534 NCBI chr 7:30,117,977...30,141,757
Ensembl chr 7:30,117,977...30,141,639 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO senecionine results in decreased expression of MSMO1 protein CTD PMID:35357534 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases expression ISO senecionine results in increased expression of COX3 protein CTD PMID:35357534 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382 		JBrowse link
G Mt-nd3 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 decreases expression ISO senecionine results in decreased expression of ND3 protein CTD PMID:35357534 NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
NCBI chr MT:9,451...9,798
Ensembl chr MT:9,451...9,798 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO senecionine results in increased expression of MT2 mRNA CTD PMID:31606820 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression ISO senecionine results in increased expression of MTHFD1L protein CTD PMID:35357534 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression ISO senecionine results in decreased expression of MTSS1 protein CTD PMID:35357534 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 decreases expression ISO senecionine results in decreased expression of MTUS1 protein CTD PMID:35357534 NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP senecionine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP senecionine results in increased expression of MYBL2 mRNA CTD PMID:32419051 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression EXP senecionine results in decreased expression of MYBPC3 mRNA CTD PMID:34185104 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405 		JBrowse link
G Myoz2 myozenin 2 decreases expression EXP senecionine results in decreased expression of MYOZ2 mRNA CTD PMID:34185104 NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221 		JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 decreases expression ISO senecionine results in decreased expression of N4BP2L1 protein CTD PMID:35357534 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257 		JBrowse link
G Napsa napsin A aspartic peptidase increases expression ISO senecionine results in increased expression of NAPSA protein CTD PMID:35357534 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression EXP senecionine results in increased expression of NCAPH mRNA CTD PMID:32419051 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncf4 neutrophil cytosolic factor 4 increases expression ISO senecionine results in increased expression of NCF4 protein CTD PMID:35357534 NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389 		JBrowse link
G Ndc80 NDC80 kinetochore complex component increases expression EXP senecionine results in increased expression of NDC80 mRNA CTD PMID:32419051 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Neb nebulin decreases expression ISO senecionine results in decreased expression of NEB mRNA CTD PMID:26100227 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574 		JBrowse link
G Nfia nuclear factor I/A decreases expression ISO senecionine results in decreased expression of NFIA protein CTD PMID:35357534 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression ISO senecionine results in decreased expression of NIFK protein CTD PMID:35357534 NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896 		JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO senecionine results in decreased expression of NNMT mRNA CTD PMID:26100227 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Nop16 NOP16 nucleolar protein decreases expression ISO senecionine results in decreased expression of NOP16 protein CTD PMID:35357534 NCBI chr17:10,022,950...10,027,867
Ensembl chr17:10,022,932...10,027,867 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO senecionine results in increased expression of NOS2 mRNA CTD PMID:35357534 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase increases expression ISO senecionine results in increased expression of NPL protein CTD PMID:35357534 NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO senecionine results in increased expression of NQO1 mRNA CTD PMID:26100227 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression EXP
ISO		 senecionine results in decreased expression of NR0B2 mRNA CTD PMID:24641316 PMID:31606820 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO senecionine results in increased expression of NR1D1 protein CTD PMID:35357534 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP
ISO		 senecionine results in decreased expression of NR1H4 mRNA
senecionine results in decreased expression of NR1H4 protein		 CTD PMID:24641316 PMID:35357534 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO senecionine results in decreased expression of NR1I3 mRNA CTD PMID:31606820 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP senecionine results in decreased expression of NR3C1 mRNA CTD PMID:32419051 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP senecionine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrg1 neuregulin 1 increases expression EXP senecionine results in increased expression of NRG1 mRNA CTD PMID:32419051 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 decreases expression ISO senecionine results in decreased expression of NRP1 protein CTD PMID:35357534 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Ntm neurotrimin decreases expression ISO senecionine results in decreased expression of NTM protein CTD PMID:35357534 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 decreases expression ISO senecionine results in decreased expression of NUCKS1 protein CTD PMID:35357534 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229 		JBrowse link
G Nudt7 nudix hydrolase 7 increases expression ISO senecionine results in increased expression of NUDT7 protein CTD PMID:35357534 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression EXP senecionine results in increased expression of NUSAP1 mRNA CTD PMID:32419051 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Orm1 orosomucoid 1 decreases expression ISO senecionine results in decreased expression of ORM1 protein CTD PMID:35357534 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial increases expression ISO senecionine results in increased expression of OXSM protein CTD PMID:35357534 NCBI chr15:9,210,443...9,215,852
Ensembl chr15:9,210,547...9,214,558 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression ISO senecionine results in decreased expression of PABPC1 protein CTD PMID:35357534 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO senecionine results in decreased expression of PARP1 protein CTD PMID:29458164 PMID:35357534 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pclaf PCNA clamp associated factor increases expression EXP senecionine results in increased expression of PCLAF mRNA CTD PMID:32419051 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO senecionine results in decreased expression of PCSK9 protein CTD PMID:35357534 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Pdcl phosducin like increases expression ISO senecionine results in increased expression of PDCL protein CTD PMID:35357534 NCBI chr 3:21,110,165...21,119,763
Ensembl chr 3:21,110,167...21,119,715 		JBrowse link
G Pde12 phosphodiesterase 12 increases expression ISO senecionine results in increased expression of PDE12 protein CTD PMID:35357534 NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887 		JBrowse link
G Pde7b phosphodiesterase 7B decreases expression ISO senecionine results in decreased expression of PDE7B protein CTD PMID:35357534 NCBI chr 1:15,174,001...15,493,267
Ensembl chr 1:15,182,704...15,492,900 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 decreases expression ISO senecionine results in decreased expression of PDIA2 protein CTD PMID:35357534 NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931 		JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 decreases expression ISO senecionine results in decreased expression of PDZRN3 protein CTD PMID:35357534 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959 		JBrowse link
G Per3 period circadian regulator 3 decreases expression ISO senecionine results in decreased expression of PER3 protein CTD PMID:35357534 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Phf14 PHD finger protein 14 decreases expression ISO senecionine results in decreased expression of PHF14 protein CTD PMID:35357534 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 decreases expression ISO senecionine results in decreased expression of PID1 protein CTD PMID:35357534 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Piezo1 piezo-type mechanosensitive ion channel component 1 increases expression ISO senecionine results in increased expression of PIEZO1 protein CTD PMID:35357534 NCBI chr19:50,544,580...50,606,812
Ensembl chr19:50,544,582...50,606,501 		JBrowse link
G Pigr polymeric immunoglobulin receptor decreases expression ISO senecionine results in decreased expression of PIGR protein CTD PMID:35357534 NCBI chr13:42,298,905...42,326,877
Ensembl chr13:42,298,914...42,326,875 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel decreases expression ISO senecionine results in decreased expression of PKD2 protein CTD PMID:35357534 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Plcg2 phospholipase C, gamma 2 increases expression ISO senecionine results in increased expression of PLCG2 protein CTD PMID:35357534 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pld1 phospholipase D1 decreases expression ISO senecionine results in decreased expression of PLD1 protein CTD PMID:35357534 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692 		JBrowse link
G Pld4 phospholipase D family, member 4 increases expression EXP senecionine results in increased expression of PLD4 mRNA CTD PMID:34185104 NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376 		JBrowse link
G Plg plasminogen decreases expression ISO senecionine results in decreased expression of PLG protein CTD PMID:35357534 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Plin2 perilipin 2 increases expression ISO senecionine results in increased expression of PLIN2 protein CTD PMID:35357534 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plk4 polo-like kinase 4 increases expression EXP senecionine results in increased expression of PLK4 mRNA CTD PMID:32419051 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Pln phospholamban decreases expression EXP senecionine results in decreased expression of PLN mRNA CTD PMID:34185104 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO senecionine results in decreased expression of PML protein CTD PMID:35357534 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression ISO senecionine results in increased expression of PNPLA2 protein CTD PMID:35357534 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Polr1g RNA polymerase I subunit G increases expression ISO senecionine results in increased expression of POLR1G protein CTD PMID:35357534 NCBI chr 1:79,007,490...79,010,766
Ensembl chr 1:79,007,490...79,010,766 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
affects response to substance		 ISO POR protein affects the reaction [senecionine results in increased expression of GPT protein]
POR protein affects the susceptibility to senecionine		 CTD PMID:31606820 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppif peptidylprolyl isomerase F increases expression ISO senecionine results in increased expression of PPIF protein CTD PMID:35357534 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO senecionine results in decreased expression of PPP1R3B protein CTD PMID:35357534 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression EXP senecionine results in increased expression of PRC1 mRNA CTD PMID:32419051 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO senecionine results in increased expression of PRDX3 protein CTD PMID:35357534 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prg4 proteoglycan 4 decreases expression ISO senecionine results in decreased expression of PRG4 protein CTD PMID:35357534 NCBI chr13:62,487,257...62,504,657
Ensembl chr13:62,487,257...62,504,119 		JBrowse link
G Prlr prolactin receptor decreases expression ISO senecionine results in decreased expression of PRLR protein CTD PMID:35357534 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Prox1 prospero homeobox 1 decreases expression ISO senecionine results in decreased expression of PROX1 protein CTD PMID:35357534 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Prr12 proline rich 12 decreases expression ISO senecionine results in decreased expression of PRR12 protein CTD PMID:35357534 NCBI chr 1:95,510,015...95,534,002
Ensembl chr 1:95,509,931...95,533,652 		JBrowse link
G Psap prosaposin decreases expression ISO senecionine results in decreased expression of PSAP protein CTD PMID:35357534 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 decreases expression ISO senecionine results in decreased expression of PSIP1 protein CTD PMID:35357534 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 increases expression ISO senecionine results in increased expression of PSMD10 protein CTD PMID:35357534 NCBI chr  X:104,656,809...104,665,122
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO senecionine metabolite results in decreased expression of PTGIS mRNA; senecionine metabolite results in decreased expression of PTGIS protein CTD PMID:30465738 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO senecionine metabolite results in increased expression of PTGS2 mRNA; senecionine metabolite results in increased expression of PTGS2 protein CTD PMID:30465738 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO senecionine results in decreased expression of PTPRD mRNA
senecionine results in decreased expression of PTPRD protein		 CTD PMID:26100227 PMID:35357534 NCBI chr 5:90,046,993...90,698,977
NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family decreases expression ISO senecionine results in decreased expression of RAB11A protein CTD PMID:35357534 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO senecionine results in decreased expression of RAPGEF4 mRNA CTD PMID:26100227 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rassf1 Ras association domain family member 1 increases expression ISO senecionine results in increased expression of RASSF1 protein CTD PMID:35357534 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rbis ribosomal biogenesis factor decreases expression ISO senecionine results in decreased expression of RBIS protein CTD PMID:35357534 NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339 		JBrowse link
G Rbm3 RNA binding motif protein 3 decreases expression ISO senecionine results in decreased expression of RBM3 protein CTD PMID:35357534 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 increases expression ISO senecionine results in increased expression of RC3H1 protein CTD PMID:35357534 NCBI chr13:73,174,075...73,245,762
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Rcl1 RNA terminal phosphate cyclase-like 1 decreases expression ISO senecionine results in decreased expression of RCL1 protein CTD PMID:35357534 NCBI chr 1:226,824,561...226,869,046
Ensembl chr 1:226,824,534...226,902,315 		JBrowse link
G Rexo4 REX4 homolog, 3'-5' exonuclease decreases expression ISO senecionine results in decreased expression of REXO4 protein CTD PMID:35357534 NCBI chr 3:10,280,654...10,291,003
Ensembl chr 3:10,280,654...10,290,996 		JBrowse link
G Ring1 ring finger protein 1 decreases expression ISO senecionine results in decreased expression of RING1 protein CTD PMID:35357534 NCBI chr20:4,830,120...4,833,623
Ensembl chr20:4,830,053...4,833,620 		JBrowse link
G Rpl34 ribosomal protein L34 decreases expression ISO senecionine results in decreased expression of RPL34 protein CTD PMID:35357534 NCBI chr 2:219,284,373...219,288,108
Ensembl chr 2:219,284,382...219,288,111 		JBrowse link
G Rpl36 ribosomal protein L36 decreases expression ISO senecionine results in decreased expression of RPL36 protein CTD PMID:35357534 NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 increases expression ISO senecionine results in increased expression of RPLP1 protein CTD PMID:35357534 NCBI chr 8:62,394,008...62,395,341
Ensembl chr 8:62,393,177...62,395,339 		JBrowse link
G Rps27 ribosomal protein S27 decreases expression ISO senecionine results in decreased expression of RPS27 protein CTD PMID:35357534 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO senecionine results in increased expression of RRAD mRNA CTD PMID:26100227 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G RragB Ras-related GTP binding B increases expression ISO senecionine results in increased expression of RRAGB protein CTD PMID:35357534 NCBI chr  X:18,184,619...18,234,639
Ensembl chr  X:18,184,992...18,234,639 		JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO senecionine results in decreased expression of RRBP1 protein CTD PMID:35357534 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression EXP senecionine results in increased expression of RRM1 mRNA CTD PMID:32419051 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor increases expression ISO senecionine results in increased expression of RRN3 protein CTD PMID:35357534 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO senecionine results in increased expression of RSAD2 protein CTD PMID:35357534 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rsl24d1 ribosomal L24 domain containing 1 decreases expression ISO senecionine results in decreased expression of RSL24D1 protein CTD PMID:35357534 NCBI chr 8:73,852,991...73,861,996
Ensembl chr 8:73,852,996...73,862,001 		JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO senecionine results in decreased expression of RXRA protein CTD PMID:35357534 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO senecionine results in increased expression of S100A4 protein CTD PMID:35357534 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO senecionine results in increased expression of S100A6 protein CTD PMID:35357534 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO senecionine results in increased expression of S100A9 protein CTD PMID:35357534 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Saa4 serum amyloid A4 decreases expression ISO senecionine results in decreased expression of SAA4 protein CTD PMID:35357534 NCBI chr 1:97,247,580...97,251,882 JBrowse link
G Sarnp SAP domain containing ribonucleoprotein decreases expression ISO senecionine results in decreased expression of SARNP protein CTD PMID:35357534 NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO senecionine results in increased expression of SAT1 mRNA CTD PMID:26100227 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO senecionine results in decreased expression of SCD1 protein CTD PMID:35357534 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdc2 syndecan 2 decreases expression ISO senecionine results in decreased expression of SDC2 protein CTD PMID:35357534 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081 		JBrowse link
G Sdc4 syndecan 4 decreases expression ISO senecionine results in decreased expression of SDC4 protein CTD PMID:35357534 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression ISO senecionine results in increased expression of SDR42E1 protein CTD PMID:35357534 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901 		JBrowse link
G Secisbp2l SECIS binding protein 2-like decreases expression ISO senecionine results in decreased expression of SECISBP2L protein CTD PMID:35357534 NCBI chr 3:112,989,613...113,036,060
Ensembl chr 3:112,991,908...113,035,884 		JBrowse link
G Sema3e semaphorin 3E decreases expression ISO senecionine results in decreased expression of SEMA3E protein CTD PMID:35357534 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Sema4b semaphorin 4B decreases expression ISO senecionine results in decreased expression of SEMA4B protein CTD PMID:35357534 NCBI chr 1:134,136,646...134,177,777
Ensembl chr 1:134,149,536...134,177,775 		JBrowse link
G Serpina10 serpin family A member 10 decreases expression ISO senecionine results in decreased expression of SERPINA10 protein CTD PMID:35357534 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544 		JBrowse link
G Serpina3n serpin family A member 3N decreases expression ISO senecionine results in decreased expression of SERPINA3N protein CTD PMID:35357534 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpina7 serpin family A member 7 increases expression ISO senecionine results in increased expression of SERPINA7 protein CTD PMID:35357534 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040 		JBrowse link
G Sft2d3 SFT2 domain containing 3 increases expression ISO senecionine results in increased expression of SFT2D3 protein CTD PMID:35357534 NCBI chr18:23,537,105...23,539,305
Ensembl chr18:23,537,105...23,539,305 		JBrowse link
G Sgcb sarcoglycan, beta increases expression EXP senecionine results in increased expression of SGCB mRNA CTD PMID:32419051 NCBI chr14:34,563,614...34,578,614
Ensembl chr14:34,563,608...34,578,583 		JBrowse link
G Sh3bp5 SH3-domain binding protein 5 decreases expression ISO senecionine results in decreased expression of SH3BP5 protein CTD PMID:35357534 NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A decreases expression ISO senecionine results in decreased expression of SH3PXD2A protein CTD PMID:35357534 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP
ISO		 senecionine results in decreased expression of SLC10A1 mRNA CTD PMID:24641316 PMID:31606820 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc16a12 solute carrier family 16, member 12 decreases expression ISO senecionine results in decreased expression of SLC16A12 protein CTD PMID:35357534 NCBI chr 1:232,184,004...232,262,170
Ensembl chr 1:232,185,907...232,262,141 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 increases expression ISO senecionine results in increased expression of SLC16A2 protein CTD PMID:35357534 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression ISO senecionine results in decreased expression of SLC22A1 mRNA CTD PMID:31606820 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO senecionine results in decreased expression of SLC22A9 mRNA CTD PMID:26100227 NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO senecionine results in decreased expression of SLC22A7 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Slc25a47 solute carrier family 25, member 47 increases expression ISO senecionine results in increased expression of SLC25A47 protein CTD PMID:35357534 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO senecionine results in increased expression of SLC2A3 protein CTD PMID:35357534 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO senecionine results in decreased expression of SLC30A10 protein CTD PMID:35357534 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Slc31a2 solute carrier family 31 member 2 decreases expression ISO senecionine results in decreased expression of SLC31A2 protein CTD PMID:35357534 NCBI chr 5:75,738,008...75,748,542
Ensembl chr 5:75,738,024...75,748,542 		JBrowse link
G Slc38a4 solute carrier family 38, member 4 decreases expression ISO senecionine results in decreased expression of SLC38A4 protein CTD PMID:35357534 NCBI chr 7:128,142,866...128,203,000
Ensembl chr 7:128,144,807...128,202,995 		JBrowse link
G Slc39a14 solute carrier family 39 member 14 decreases expression ISO senecionine results in decreased expression of SLC39A14 protein CTD PMID:35357534 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524 		JBrowse link
G Slc3a1 solute carrier family 3 member 1 decreases expression ISO senecionine results in decreased expression of SLC3A1 protein CTD PMID:35357534 NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 decreases expression ISO senecionine results in decreased expression of SLC6A12 protein CTD PMID:35357534 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP senecionine results in decreased expression of SLCO1A2 mRNA CTD PMID:24641316 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP
ISO		 senecionine results in decreased expression of SLCO1B2 mRNA
senecionine results in decreased expression of SLCO1B3 mRNA		 CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression EXP senecionine results in increased expression of SMC2 mRNA CTD PMID:32419051 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression EXP senecionine results in increased expression of SMC4 mRNA CTD PMID:32419051 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 decreases expression ISO senecionine results in decreased expression of SMC6 protein CTD PMID:35357534 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 decreases expression ISO senecionine results in decreased expression of SMOC1 protein CTD PMID:35357534 NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699 		JBrowse link
G Smpx small muscle protein, X-linked decreases expression EXP senecionine results in decreased expression of SMPX mRNA CTD PMID:34185104 NCBI chr  X:37,233,209...37,292,266
Ensembl chr  X:37,234,294...37,276,708 		JBrowse link
G Snd1 staphylococcal nuclease and tudor domain containing 1 decreases expression ISO senecionine results in decreased expression of SND1 protein CTD PMID:35357534 NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843 		JBrowse link
G Soat1 sterol O-acyltransferase 1 decreases expression ISO senecionine results in decreased expression of SOAT1 protein CTD PMID:35357534 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494 		JBrowse link
G Sqle squalene epoxidase decreases expression ISO senecionine results in decreased expression of SQLE protein CTD PMID:35357534 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO senecionine results in decreased expression of SREBF1 protein CTD PMID:35357534 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Sri sorcin increases expression ISO senecionine results in increased expression of SRI protein CTD PMID:35357534 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Srl sarcalumenin decreases expression EXP senecionine results in decreased expression of SRL mRNA CTD PMID:34185104 NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP senecionine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589 		JBrowse link
G Stc1 stanniocalcin 1 increases expression EXP senecionine results in increased expression of STC1 mRNA CTD PMID:34185104 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Steap4 STEAP4 metalloreductase increases expression
decreases expression		 EXP
ISO		 senecionine results in increased expression of STEAP4 mRNA
senecionine results in decreased expression of STEAP4 protein		 CTD PMID:34185104 PMID:35357534 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
G Stil STIL, centriolar assembly protein increases expression EXP senecionine results in increased expression of STIL mRNA CTD PMID:32419051 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Stmn1 stathmin 1 increases expression EXP senecionine results in increased expression of STMN1 mRNA CTD PMID:32419051 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Ston1 stonin 1 increases expression ISO senecionine results in increased expression of STON1 protein CTD PMID:35357534 NCBI chr 6:5,843,186...5,892,557
Ensembl chr 6:5,843,185...5,892,449 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta increases expression ISO senecionine results in increased expression of SUCLG2 protein CTD PMID:35357534 NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO senecionine results in decreased expression of SULT1E1 mRNA CTD PMID:26100227 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO senecionine results in decreased expression of SULT2A1 mRNA CTD PMID:31606820 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Surf2 surfeit 2 increases expression ISO senecionine results in increased expression of SURF2 protein CTD PMID:35357534 NCBI chr 3:10,244,654...10,248,502
Ensembl chr 3:10,244,654...10,250,077 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor decreases expression ISO senecionine results in decreased expression of SYF2 protein CTD PMID:35357534 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414 		JBrowse link
G Tcf19 transcription factor 19 increases expression EXP senecionine results in increased expression of TCF19 mRNA CTD PMID:32419051 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271 		JBrowse link
G Tdrd1 tudor domain containing 1 increases expression ISO senecionine results in increased expression of TDRD1 protein CTD PMID:35357534 NCBI chr 1:255,871,939...255,919,222
Ensembl chr 1:255,875,887...255,915,871 		JBrowse link
G Tecpr1 tectonin beta-propeller repeat containing 1 increases expression ISO senecionine results in increased expression of TECPR1 protein CTD PMID:35357534 NCBI chr12:10,391,587...10,420,462
Ensembl chr12:10,391,696...10,419,611 		JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO senecionine results in decreased expression of TENM1 mRNA CTD PMID:26100227 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207 		JBrowse link
G Tenm2 teneurin transmembrane protein 2 decreases expression ISO senecionine results in decreased expression of TENM2 mRNA CTD PMID:26100227 NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO senecionine results in increased expression of TGFB1 mRNA; senecionine results in increased expression of TGFB1 protein CTD PMID:35357534 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions		 ISO senecionine results in increased expression of THBS1 mRNA; senecionine results in increased expression of THBS1 protein
Leu-Ser-Lys-Leu peptide inhibits the reaction [senecionine results in increased expression of THBS1 mRNA]; senecionine promotes the reaction [Pyrrolizidine Alkaloids binds to THBS1 protein]		 CTD PMID:35357534 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Tlr8 toll-like receptor 8 increases expression EXP senecionine results in increased expression of TLR8 mRNA CTD PMID:34185104 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549 		JBrowse link
G Tma7 translation machinery associated 7 homolog decreases expression ISO senecionine results in decreased expression of TMA7 protein CTD PMID:35357534 NCBI chr 8:109,726,213...109,730,902
Ensembl chr 8:109,726,196...109,735,474 		JBrowse link
G Tmem144 transmembrane protein 144 increases expression ISO senecionine results in increased expression of TMEM144 protein CTD PMID:35357534 NCBI chr 2:164,960,649...164,993,562
Ensembl chr 2:164,961,247...164,992,368 		JBrowse link
G Tmem176a transmembrane protein 176A decreases expression ISO senecionine results in decreased expression of TMEM176A protein CTD PMID:35357534 NCBI chr 4:77,774,940...77,778,620
Ensembl chr 4:77,774,843...77,778,620 		JBrowse link
G Tmem176b transmembrane protein 176B decreases expression ISO senecionine results in decreased expression of TMEM176B protein CTD PMID:35357534 NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384 		JBrowse link
G Tmem208 transmembrane protein 208 decreases expression ISO senecionine results in decreased expression of TMEM208 protein CTD PMID:35357534 NCBI chr19:33,203,587...33,206,287
Ensembl chr19:33,203,587...33,212,183 		JBrowse link
G Tmem35b transmembrane protein 35B increases expression ISO senecionine results in increased expression of TMEM35B protein CTD PMID:35357534 NCBI chr 5:139,446,317...139,449,947
Ensembl chr 5:139,444,399...139,449,947 		JBrowse link
G Tmem87b transmembrane protein 87B decreases expression ISO senecionine results in decreased expression of TMEM87B protein CTD PMID:35357534 NCBI chr 3:116,061,933...116,097,421
Ensembl chr 3:116,062,204...116,097,367 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression EXP senecionine results in increased expression of TNFRSF1B mRNA CTD PMID:34185104 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 decreases expression ISO senecionine results in decreased expression of TNIP2 protein CTD PMID:35357534 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type decreases expression EXP senecionine results in decreased expression of TNNC1 mRNA CTD PMID:34185104 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634 		JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP senecionine results in increased expression of TOP2A mRNA CTD PMID:32419051 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase decreases expression ISO senecionine results in decreased expression of TOPORS protein CTD PMID:35357534 NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937 		JBrowse link
G Tox thymocyte selection-associated high mobility group box decreases expression ISO senecionine results in decreased expression of TOX protein CTD PMID:35357534 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO senecionine results in increased expression of TRP53 mRNA; senecionine results in increased expression of TRP53 protein
senecionine results in increased expression of TP53 mRNA		 CTD PMID:35357534 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpmt thiopurine S-methyltransferase increases expression ISO senecionine results in increased expression of TPMT mRNA CTD PMID:26100227 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor increases expression EXP senecionine results in increased expression of TPX2 mRNA CTD PMID:32419051 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 increases expression ISO senecionine results in increased expression of TREML1 protein CTD PMID:35357534 NCBI chr 9:12,635,584...12,642,324
Ensembl chr 9:12,635,590...12,642,347 		JBrowse link
G Tsr2 TSR2, ribosome maturation factor decreases expression ISO senecionine results in decreased expression of TSR2 protein CTD PMID:35357534 NCBI chr  X:20,064,102...20,072,673
Ensembl chr  X:20,064,103...20,072,620 		JBrowse link
G Tstd3 thiosulfate sulfurtransferase like domain containing 3 increases expression ISO senecionine results in increased expression of TSTD3 protein CTD PMID:35357534 NCBI chr 5:35,294,652...35,304,093
Ensembl chr 5:35,294,645...35,304,101 		JBrowse link
G Ttk Ttk protein kinase increases expression EXP senecionine results in increased expression of TTK mRNA CTD PMID:32419051 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Ttr transthyretin decreases expression ISO senecionine results in decreased expression of TTR protein CTD PMID:35357534 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tuft1 tuftelin 1 increases expression ISO senecionine results in increased expression of TUFT1 protein CTD PMID:35357534 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192 		JBrowse link
G Tyms thymidylate synthetase increases expression EXP senecionine results in increased expression of TYMS mRNA CTD PMID:32419051 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ubl3 ubiquitin-like 3 decreases expression ISO senecionine results in decreased expression of UBL3 protein CTD PMID:35357534 NCBI chr12:6,473,684...6,518,331
Ensembl chr12:6,473,460...6,518,862 		JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 increases expression ISO senecionine results in increased expression of UCHL3 mRNA CTD PMID:26100227 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
Ensembl chr 3:78,485,315...78,527,355 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 increases expression ISO senecionine results in increased expression of UCKL1 protein CTD PMID:35357534 NCBI chr 3:168,674,849...168,687,513
Ensembl chr 3:168,674,849...168,698,091 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glycosylation
multiple interactions		 ISO UGT1A4 protein results in increased glycosylation of senecionine
[hecogenin results in decreased activity of UGT1A4 protein] which results in decreased glycosylation of senecionine		 CTD PMID:20092275 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 decreases expression ISO senecionine results in decreased expression of UGT2A3 mRNA CTD PMID:26100227 NCBI chr14:20,572,793...20,590,795
Ensembl chr14:20,572,808...20,590,729 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression ISO senecionine results in decreased expression of UGT2B1 mRNA CTD PMID:31606820 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Utp11 UTP11, small subunit processome component decreases expression ISO senecionine results in decreased expression of UTP11 protein CTD PMID:35357534 NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191 		JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B decreases expression ISO senecionine results in decreased expression of VPS13B mRNA CTD PMID:26100227 NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429 		JBrowse link
G Vps36 vacuolar protein sorting 36 homolog increases expression ISO senecionine results in increased expression of VPS36 protein CTD PMID:35357534 NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810 		JBrowse link
G Wdr53 WD repeat domain 53 decreases expression ISO senecionine results in decreased expression of WDR53 protein CTD PMID:35357534 NCBI chr11:68,542,647...68,551,148
Ensembl chr11:68,542,650...68,551,112 		JBrowse link
G Wdr82 WD repeat domain 82 decreases expression ISO senecionine results in decreased expression of WDR82 protein CTD PMID:35357534 NCBI chr 8:106,814,569...106,834,535
Ensembl chr 8:106,814,569...106,834,438 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor increases expression ISO senecionine results in increased expression of XPA protein CTD PMID:35357534 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
G Xylt2 xylosyltransferase 2 decreases expression ISO senecionine results in decreased expression of XYLT2 protein CTD PMID:35357534 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
G Yipf5 Yip1 domain family, member 5 decreases expression ISO senecionine results in decreased expression of YIPF5 protein CTD PMID:35357534 NCBI chr18:32,123,814...32,136,947
Ensembl chr18:32,123,842...32,157,642 		JBrowse link
G Zcchc10 zinc finger CCHC-type containing 10 increases expression ISO senecionine results in increased expression of ZCCHC10 protein CTD PMID:35357534 NCBI chr10:37,470,628...37,481,027 JBrowse link
G Zfp106 zinc finger protein 106 increases expression ISO senecionine results in increased expression of ZNF106 protein CTD PMID:35357534 NCBI chr 3:107,459,232...107,510,507
Ensembl chr 3:107,462,096...107,510,481 		JBrowse link
G Zfp367 zinc finger protein 367 increases expression EXP senecionine results in increased expression of ZFP367 mRNA CTD PMID:32419051 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 increases expression ISO senecionine results in increased expression of ZFP36L1 protein CTD PMID:35357534 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
G Zg16 zymogen granule protein 16 decreases expression ISO senecionine results in decreased expression of ZG16 protein CTD PMID:35357534 NCBI chr 1:181,657,722...181,660,079
Ensembl chr 1:181,657,722...181,660,079 		JBrowse link
G Zwilch zwilch kinetochore protein increases expression EXP senecionine results in increased expression of ZWILCH mRNA CTD PMID:32419051 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      biological role 19885
        biochemical role 19569
          metabolite 19577
            alkaloid 8015
              pyrrolizidine alkaloid 753
                senecionine 512
                  dehydrojacoline 0
                  jacoline + 0
                  senecionine N-oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19774
                        carbon atom 19790
                          organic molecular entity 19790
                            organic molecule 19743
                              organic cyclic compound 19533
                                organic heterocyclic compound 18903
                                  organic heteropolycyclic compound 18317
                                    organic heterobicyclic compound 17257
                                      pyrrolizines 830
                                        pyrrolizine alkaloid 631
                                          senecionan 631
                                            senecionine 512
                                              dehydrojacoline 0
                                              jacoline + 0
                                              senecionine N-oxide 0
paths to the root