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Accession:CHEBI:90933 term browser browse the term
Definition:An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.
Synonyms:exact_synonym: N'-(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl)-N,N-dimethylurea
 related_synonym: Formula=C21H32Cl2N4O;   InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-;   InChIKey=KPWSJANDNDDRMB-QAQDUYKDSA-N;   RGH 188;   SMILES=C1[C@H](CC[C@@H](C1)CCN2CCN(CC2)C=3C(=C(C=CC3)Cl)Cl)NC(N(C)C)=O
 xref: CAS:839712-12-8;   DrugBank:DB06016;   Drug_Central:5037;   KEGG:D09997
 xref_mesh: MESH:C533287
 xref: PMID:22537450;   PMID:23138433;   PMID:23966785;   PMID:24048386;   PMID:24229617;   PMID:24412468;   PMID:24975932;   PMID:25056368;   PMID:25083572;   PMID:25532076;   PMID:25562205;   PMID:25692006;   PMID:26044980;   PMID:26075487;   PMID:26160196;   PMID:26419293;   PMID:26472602;   PMID:26510944;   PMID:26541814;   PMID:26586950;   PMID:26655189;   PMID:26655732;   PMID:26717533;   PMID:26723167;   Reaxys:18784658;   Wikipedia:Cariprazine
 cyclic_relationship: is_conjugate_base_of CHEBI:90934

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cariprazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19790
    role 19738
      application 19385
        agrochemical 14457
          fertilizer 11796
            urea 4989
              ureas 4987
                cariprazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    p-block element atom 19674
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18475
                              organic divalent group 18468
                                organodiyl group 18468
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18034
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16928
                                              carboxamide 16928
                                                monocarboxylic acid amide 14575
                                                  urea 4989
                                                    ureas 4987
                                                      cariprazine 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.