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Accession:CHEBI:90933 term browser browse the term
Definition:An N-alkylpiperazine that is N,N-dimethyl-N'-{trans-4-[2-(piperazin-1-yl)ethyl]cyclohexyl}urea substituted at position 4 on the piperazine ring by a 2,3-dichlorophenyl group. Used (as the hydrochloride salt) for treatment of schizophrenia and bipolar disorder.
Synonyms:exact_synonym: N'-(trans-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl)-N,N-dimethylurea
 related_synonym: Formula=C21H32Cl2N4O;   InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17-;   InChIKey=KPWSJANDNDDRMB-QAQDUYKDSA-N;   RGH 188;   SMILES=C1[C@H](CC[C@@H](C1)CCN2CCN(CC2)C=3C(=C(C=CC3)Cl)Cl)NC(N(C)C)=O
 xref: CAS:839712-12-8;   DrugBank:DB06016;   Drug_Central:5037;   KEGG:D09997
 xref_mesh: MESH:C533287
 xref: PMID:22537450;   PMID:23138433;   PMID:23966785;   PMID:24048386;   PMID:24229617;   PMID:24412468;   PMID:24975932;   PMID:25056368;   PMID:25083572;   PMID:25532076;   PMID:25562205;   PMID:25692006;   PMID:26044980;   PMID:26075487;   PMID:26160196;   PMID:26419293;   PMID:26472602;   PMID:26510944;   PMID:26541814;   PMID:26586950;   PMID:26655189;   PMID:26655732;   PMID:26717533;   PMID:26723167;   Reaxys:18784658;   Wikipedia:Cariprazine
 cyclic_relationship: is_conjugate_base_of CHEBI:90934

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cariprazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      application 19381
        agrochemical 14442
          fertilizer 11776
            urea 4985
              ureas 4983
                cariprazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19569
                        carbon atom 19558
                          organic molecular entity 19558
                            organic group 18473
                              organic divalent group 18467
                                organodiyl group 18467
                                  carbonyl group 18366
                                    carbonyl compound 18366
                                      carboxylic acid 18038
                                        carboacyl group 17193
                                          univalent carboacyl group 17193
                                            carbamoyl group 16931
                                              carboxamide 16931
                                                monocarboxylic acid amide 14574
                                                  urea 4985
                                                    ureas 4983
                                                      cariprazine 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.