Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:(-)-selegiline
go back to main search page
Accession:CHEBI:9086 term browser browse the term
Definition:A selegiline that has formula C13H17N.
Synonyms:exact_synonym: N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine
 related_synonym: EmSam;   Formula=C13H17N;   InChI=1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1;   InChIKey=MEZLKOACVSPNER-GFCCVEGCSA-N;   L-Deprenalin;   SMILES=C[C@H](Cc1ccccc1)N(C)CC#C;   selegilina;   selegilinum
 xref: Beilstein:5863318 "Beilstein";   CAS:14611-51-9 "ChemIDplus";   CAS:14611-51-9 "KEGG COMPOUND";   DrugBank:DB01037;   Drug_Central:2429 "DrugCentral";   KEGG:C07245;   KEGG:D03731;   LINCS:LSM-5920
 xref_mesh: MESH:D012642
 xref: Patent:NL6605956;   Patent:US4564706;   Wikipedia:Selegiline
 cyclic_relationship: is_conjugate_base_of CHEBI:50350


show annotations for term's descendants       view all columns           Sort by:
 
(-)-selegiline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AIFM1 apoptosis inducing factor mitochondria associated 1 JBrowse link X 130,129,362 130,165,887 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G BACH1 BTB domain and CNC homolog 1 JBrowse link 21 29,298,922 29,361,896 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYCS cytochrome c, somatic JBrowse link 7 25,118,656 25,125,260 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G GAPDH glyceraldehyde-3-phosphate dehydrogenase JBrowse link 12 6,534,517 6,538,371 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G MAOA monoamine oxidase A JBrowse link X 43,654,907 43,746,824 RGD:6480464
G MAOB monoamine oxidase B JBrowse link X 43,766,610 43,882,450 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MT1X metallothionein 1X JBrowse link 16 56,682,470 56,684,196 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PRKN parkin RBR E3 ubiquitin protein ligase JBrowse link 6 161,347,417 162,727,802 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G SIAH1 siah E3 ubiquitin protein ligase 1 JBrowse link 16 48,354,581 48,448,435 RGD:6480464
G SLC22A2 solute carrier family 22 member 2 JBrowse link 6 160,216,755 160,258,821 RGD:6480464
G SNCA synuclein alpha JBrowse link 4 89,724,099 89,838,324 RGD:6480464
G TH tyrosine hydroxylase JBrowse link 11 2,163,929 2,174,081 RGD:6480464
G TXN thioredoxin JBrowse link 9 110,243,810 110,256,507 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23759
    role 23648
      biological role 23611
        biochemical role 22959
          metabolite 22851
            alkaloid 5474
              phenethylamine alkaloid 56
                selegiline 31
                  (-)-selegiline 31
Path 2
Term Annotations click to browse term
  CHEBI ontology 23759
    subatomic particle 23708
      composite particle 23708
        hadron 23708
          baryon 23708
            nucleon 23708
              atomic nucleus 23708
                atom 23708
                  main group element atom 23528
                    main group molecular entity 23528
                      s-block molecular entity 22719
                        hydrogen molecular entity 22514
                          hydrides 20576
                            inorganic hydride 18791
                              pnictogen hydride 18753
                                nitrogen hydride 18457
                                  azane 18317
                                    ammonia 18314
                                      organic amino compound 18313
                                        tertiary amino compound 8737
                                          tertiary amine 606
                                            selegiline 31
                                              (-)-selegiline 31
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.