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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:inverse agonist
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Accession:CHEBI:90847 term browser browse the term
Definition:A substance that binds to the same receptor binding-site as an agonist for that receptor, but which exerts the opposite pharmacological effect.
Synonyms:related_synonym: inverse agonists
 xref: Wikipedia:Inverse_agonist

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SR9243 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO SR9243 results in decreased expression of POU5F1 protein CTD PMID:31932555 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      biological role 19782
        pharmacological role 19031
          inverse agonist 1
            5-hydroxytryptamine 2A receptor inverse agonist + 0
            liver X receptor inverse agonist + 1
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