Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Se-methylselenocysteine
go back to main search page
Accession:CHEBI:9068 term browser browse the term
Definition:An alpha-amino acid compound having methylselanylmethyl as the side-chain.
Synonyms:exact_synonym: 2-amino-3-methylselanylpropanoic acid
 related_synonym: 3-(Methylseleno)alanine;   Formula=C4H9NO2Se;   InChI=1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7);   InChIKey=XDSSPSLGNGIIHP-UHFFFAOYSA-N;   SMILES=C[Se]CC(N)C(O)=O;   Se-Methyl-selenocysteine;   Selenium methyl cysteine;   Selenohomocysteine;   Selenomethylselenocysteine
 xref: Beilstein:3930828;   CAS:2574-71-2
 xref_mesh: MESH:C002979
 cyclic_relationship: is_conjugate_acid_of CHEBI:53128;   is_conjugate_base_of CHEBI:53132


show annotations for term's descendants           Sort by:
Se-methylselenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions
decreases expression		 ISO Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Ar androgen receptor decreases expression EXP
ISO		 selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA		 CTD PMID:16637076 PMID:19025659 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Banp BTG3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr 8:122,674,711...122,755,999
Ensembl chr 8:122,676,489...122,755,997 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of BCL2 mRNA
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein
selenomethylselenocysteine results in decreased expression of BCL2 protein		 CTD PMID:11396176 PMID:19360359 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of BMAL1 mRNA CTD PMID:19122877 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Bmf BCL2 modifying factor multiple interactions
increases expression		 ISO
EXP		 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein		 CTD PMID:25321483 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression		 EXP
ISO		 selenomethylselenocysteine results in increased activity of CASP3 protein
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]		 CTD PMID:15318939 PMID:25321483 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions		 ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]		 CTD PMID:25321483 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression		 ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein		 CTD PMID:11396176 PMID:18855134 PMID:19276161 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein		 CTD PMID:25321483 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176 PMID:19276161 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr 8:123,931,000...123,939,527
Ensembl chr 8:123,931,003...123,939,502 		JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col1a2 collagen, type I, alpha 2 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Col4a5 collagen, type IV, alpha 5 increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230 		JBrowse link
G Col6a1 collagen, type VI, alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002 		JBrowse link
G Col7a1 collagen, type VII, alpha 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 9:108,782,654...108,813,943
Ensembl chr 9:108,782,654...108,813,943 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression ISO selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions ISO [selenomethylselenocysteine co-treated with Irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dbp D site albumin promoter binding protein increases expression ISO selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310 		JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr11:3,199,907...3,221,882
Ensembl chr11:3,137,360...3,216,415 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein		 CTD PMID:18855134 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fasl Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression EXP selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression		 ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein		 CTD PMID:18514395 PMID:19033020 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Grik1 glutamate receptor, ionotropic, kainate 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr16:87,692,789...88,087,751
Ensembl chr16:87,692,788...88,087,153 		JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966 		JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:101,328,244...101,549,005
Ensembl chr  X:101,328,245...101,548,965 		JBrowse link
G Igf1r insulin-like growth factor I receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Jun jun proto-oncogene increases phosphorylation ISO selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Klk1 kallikrein 1 decreases expression EXP selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions
decreases expression		 ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein		 CTD PMID:18855134 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr17:24,955,567...24,961,752
Ensembl chr17:24,955,616...24,961,752 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression		 ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Per2 period circadian clock 2 increases expression ISO selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Per3 period circadian clock 3 increases expression ISO selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122 		JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein		 CTD PMID:18855134 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692 		JBrowse link
G Prkce protein kinase C, epsilon decreases expression EXP selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Prkcz protein kinase C, zeta decreases expression EXP selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818 		JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 4:108,736,267...108,800,521
Ensembl chr 4:108,736,260...108,800,521 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr 8:124,532,748...124,562,030
Ensembl chr 8:124,532,724...124,562,026 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 3:144,276,188...144,303,438
Ensembl chr 3:144,276,065...144,303,441 		JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990 		JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 7:15,651,133...15,656,296
Ensembl chr 7:15,651,133...15,656,327 		JBrowse link
G Slc3a1 solute carrier family 3, member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664 		JBrowse link
G Slc6a19 solute carrier family 6 (neurotransmitter transporter), member 19 increases uptake EXP SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr13:73,827,864...73,848,899
Ensembl chr13:73,827,864...73,852,984 		JBrowse link
G Slc6a20b solute carrier family 6 (neurotransmitter transporter), member 20B increases uptake EXP SLC6A20B protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630 		JBrowse link
G Snap23 synaptosomal-associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736 		JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827 		JBrowse link
G Sp3 trans-acting transcription factor 3 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 2:72,766,774...72,810,790
Ensembl chr 2:72,766,771...72,810,790 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions ISO [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stx3 syntaxin 3 increases expression ISO selenomethylselenocysteine results in increased expression of STX3 mRNA CTD PMID:18514395 NCBI chr19:11,752,482...11,798,933
Ensembl chr19:11,752,482...11,796,767 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 4:132,039,074...132,058,007
Ensembl chr 4:132,039,074...132,056,849 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
Se-methyl-L-selenocysteine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of ABCC1 CTD PMID:15897249 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions
decreases expression		 ISO Isoflavones promotes the reaction [selenomethylselenocysteine results in decreased expression of ABCC4 mRNA] CTD PMID:19025659 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of APAF1 mRNA CTD PMID:25321483 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632 		JBrowse link
G Ar androgen receptor decreases expression EXP
ISO		 selenomethylselenocysteine results in decreased expression of AR protein
selenomethylselenocysteine results in decreased expression of AR mRNA		 CTD PMID:16637076 PMID:19025659 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BAK1 mRNA CTD PMID:25321483 NCBI chr17:27,238,786...27,247,601
Ensembl chr17:27,238,784...27,247,983 		JBrowse link
G Banp BTG3 associated nuclear protein increases expression ISO selenomethylselenocysteine results in increased expression of BANP mRNA CTD PMID:18514395 NCBI chr 8:122,674,711...122,755,999
Ensembl chr 8:122,676,489...122,755,997 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of BCL2 mRNA
selenomethylselenocysteine results in decreased expression of BCL2 protein
[selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein		 CTD PMID:11396176 PMID:19360359 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO selenomethylselenocysteine metabolite results in decreased expression of BCL2L1 mRNA CTD PMID:25321483 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA CTD PMID:25321483 NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of BMAL1 mRNA CTD PMID:19122877 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Bmf BCL2 modifying factor multiple interactions
increases expression		 ISO
EXP		 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form]; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]; HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]; selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter]; selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]
selenomethylselenocysteine metabolite results in increased expression of BMF protein
selenomethylselenocysteine metabolite results in increased expression of BMF mRNA; selenomethylselenocysteine metabolite results in increased expression of BMF protein		 CTD PMID:25321483 NCBI chr 2:118,359,238...118,385,240
Ensembl chr 2:118,359,238...118,380,168 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions		 EXP
ISO		 selenomethylselenocysteine results in increased activity of CASP3 protein
selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP3 protein modified form]		 CTD PMID:15318939 PMID:25321483 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Casp6 caspase 6 increases expression
multiple interactions		 ISO selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form
BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP6 protein modified form]		 CTD PMID:25321483 NCBI chr 3:129,695,064...129,707,761
Ensembl chr 3:129,695,074...129,707,752 		JBrowse link
G Casp8 caspase 8 increases expression ISO selenomethylselenocysteine metabolite results in increased expression of CASP8 protein modified form CTD PMID:25321483 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression		 ISO BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of CASP9 protein modified form] CTD PMID:25321483 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO selenomethylselenocysteine results in decreased expression of CCNA2 protein CTD PMID:11396176 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of CCND1 protein
selenomethylselenocysteine results in decreased expression of CCND1 mRNA; selenomethylselenocysteine results in decreased expression of CCND1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of CCND1 protein		 CTD PMID:11396176 PMID:18855134 PMID:19276161 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP selenomethylselenocysteine results in decreased phosphorylation of and results in decreased activity of CDK2 protein CTD PMID:10656618 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein
[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein		 CTD PMID:25321483 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO selenomethylselenocysteine results in increased expression of CDKN1B protein CTD PMID:11396176 PMID:19276161 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Chmp1a charged multivesicular body protein 1A increases expression ISO selenomethylselenocysteine results in increased expression of CHMP1A mRNA CTD PMID:18514395 NCBI chr 8:123,931,000...123,939,527
Ensembl chr 8:123,931,003...123,939,502 		JBrowse link
G Col1a1 collagen, type I, alpha 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A1 mRNA; selenomethylselenocysteine results in decreased expression of COL1A1 protein CTD PMID:18514395 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868 		JBrowse link
G Col1a2 collagen, type I, alpha 2 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL1A2 mRNA; selenomethylselenocysteine results in decreased expression of COL1A2 protein CTD PMID:18514395 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544 		JBrowse link
G Col4a5 collagen, type IV, alpha 5 increases expression ISO selenomethylselenocysteine results in increased expression of COL4A5 mRNA CTD PMID:18514395 NCBI chr  X:140,258,367...140,472,232
Ensembl chr  X:140,258,381...140,472,230 		JBrowse link
G Col6a1 collagen, type VI, alpha 1 increases expression ISO selenomethylselenocysteine results in increased expression of COL6A1 mRNA CTD PMID:18514395 NCBI chr10:76,544,626...76,561,869
Ensembl chr10:76,544,626...76,562,002 		JBrowse link
G Col7a1 collagen, type VII, alpha 1 decreases expression ISO selenomethylselenocysteine results in decreased expression of COL7A1 mRNA CTD PMID:18514395 NCBI chr 9:108,782,654...108,813,943
Ensembl chr 9:108,782,654...108,813,943 		JBrowse link
G Cry2 cryptochrome circadian regulator 2 increases expression ISO selenomethylselenocysteine results in increased expression of CRY2 mRNA CTD PMID:19122877 NCBI chr 2:92,233,991...92,264,426
Ensembl chr 2:92,233,991...92,264,388 		JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions ISO [selenomethylselenocysteine co-treated with Irinotecan] results in increased expression of CYP3A5 CTD PMID:15897249 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881 		JBrowse link
G Dbp D site albumin promoter binding protein increases expression ISO selenomethylselenocysteine results in increased expression of DBP mRNA CTD PMID:19122877 NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP selenomethylselenocysteine results in increased expression of DDIT3 mRNA CTD PMID:10656618 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO selenomethylselenocysteine results in decreased expression of DHCR24 mRNA CTD PMID:19025659 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310 		JBrowse link
G Drg1 developmentally regulated GTP binding protein 1 multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in decreased expression of DRG1 CTD PMID:15897249 NCBI chr11:3,199,907...3,221,882
Ensembl chr11:3,137,360...3,216,415 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [EP300 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of ESR1 protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of ESR1 protein		 CTD PMID:18855134 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Fasl Fas ligand multiple interactions ISO [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of FASLG CTD PMID:15897249 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha increases expression EXP selenomethylselenocysteine results in increased expression of GADD45A mRNA CTD PMID:10656618 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases activity
increases expression		 ISO selenomethylselenocysteine results in increased activity of GPX1 protein
selenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 protein		 CTD PMID:18514395 PMID:19033020 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO selenomethylselenocysteine results in increased expression of GPX4 mRNA CTD PMID:18514395 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273 		JBrowse link
G Grik1 glutamate receptor, ionotropic, kainate 1 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK1 mRNA CTD PMID:18514395 NCBI chr16:87,692,789...88,087,751
Ensembl chr16:87,692,788...88,087,153 		JBrowse link
G Grik3 glutamate receptor, ionotropic, kainate 3 increases expression ISO selenomethylselenocysteine results in increased expression of GRIK3 mRNA CTD PMID:18514395 NCBI chr 4:125,384,025...125,607,966
Ensembl chr 4:125,384,493...125,607,966 		JBrowse link
G Hdac8 histone deacetylase 8 multiple interactions ISO HDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr  X:101,328,244...101,549,005
Ensembl chr  X:101,328,245...101,548,965 		JBrowse link
G Igf1r insulin-like growth factor I receptor increases expression ISO selenomethylselenocysteine results in increased expression of IGF1R mRNA CTD PMID:18514395 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416 		JBrowse link
G Jun jun proto-oncogene increases phosphorylation ISO selenomethylselenocysteine results in increased phosphorylation of JUN protein CTD PMID:19276161 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Klk1 kallikrein 1 decreases expression EXP selenomethylselenocysteine results in decreased expression of KLK3 protein CTD PMID:16637076 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042 		JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions
decreases expression		 ISO [selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of MKI67 protein
selenomethylselenocysteine results in decreased expression of MKI67 protein		 CTD PMID:18855134 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases expression ISO selenomethylselenocysteine results in increased expression of MSRB1 mRNA CTD PMID:18514395 NCBI chr17:24,955,567...24,961,752
Ensembl chr17:24,955,616...24,961,752 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21213327 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21213327 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide increases expression ISO selenomethylselenocysteine results in increased expression of P4HA1 mRNA CTD PMID:18514395 NCBI chr10:59,159,019...59,209,126
Ensembl chr10:59,159,118...59,209,126 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases expression		 ISO [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form; BMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form] CTD PMID:25321483 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819 		JBrowse link
G Per2 period circadian clock 2 increases expression ISO selenomethylselenocysteine results in increased expression of PER2 mRNA CTD PMID:19122877 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Per3 period circadian clock 3 increases expression ISO selenomethylselenocysteine results in increased expression of PER3 mRNA CTD PMID:19122877 NCBI chr 4:151,081,475...151,129,167
Ensembl chr 4:151,088,109...151,129,122 		JBrowse link
G Pgr progesterone receptor decreases expression
multiple interactions		 ISO selenomethylselenocysteine results in decreased expression of PGR protein
[selenomethylselenocysteine co-treated with Tamoxifen] results in decreased expression of PGR protein		 CTD PMID:18855134 NCBI chr 9:8,890,017...8,968,612
Ensembl chr 9:8,899,834...8,968,612 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP selenomethylselenocysteine results in increased expression of PPP1R15A mRNA CTD PMID:10656618 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692 		JBrowse link
G Prkce protein kinase C, epsilon decreases expression EXP selenomethylselenocysteine results in decreased expression of PRKCE protein CTD PMID:10656618 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Prkcz protein kinase C, zeta decreases expression EXP selenomethylselenocysteine results in decreased expression of PRKCZ protein CTD PMID:10656618 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818 		JBrowse link
G Rab3b RAB3B, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB3B mRNA CTD PMID:18514395 NCBI chr 4:108,736,267...108,800,521
Ensembl chr 4:108,736,260...108,800,521 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family increases expression ISO selenomethylselenocysteine results in increased expression of RAB4A mRNA CTD PMID:18514395 NCBI chr 8:124,532,748...124,562,030
Ensembl chr 8:124,532,724...124,562,026 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP selenomethylselenocysteine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:21213327 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression ISO selenomethylselenocysteine results in increased expression of SCARB1 mRNA CTD PMID:18514395 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158 		JBrowse link
G Selenof selenoprotein F increases expression ISO selenomethylselenocysteine results in increased expression of SELENOF mRNA CTD PMID:18514395 NCBI chr 3:144,276,188...144,303,438
Ensembl chr 3:144,276,065...144,303,441 		JBrowse link
G Selenop selenoprotein P increases expression ISO selenomethylselenocysteine results in increased expression of SELENOP mRNA CTD PMID:18514395 NCBI chr15:3,300,249...3,309,992
Ensembl chr15:3,298,029...3,309,990 		JBrowse link
G Selenow selenoprotein W increases expression ISO selenomethylselenocysteine results in increased expression of SELENOW mRNA CTD PMID:18514395 NCBI chr 7:15,651,133...15,656,296
Ensembl chr 7:15,651,133...15,656,327 		JBrowse link
G Slc3a1 solute carrier family 3, member 1 increases uptake ISO SLC3A1 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664 		JBrowse link
G Slc6a19 solute carrier family 6 (neurotransmitter transporter), member 19 increases uptake EXP SLC6A19 protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr13:73,827,864...73,848,899
Ensembl chr13:73,827,864...73,852,984 		JBrowse link
G Slc6a20b solute carrier family 6 (neurotransmitter transporter), member 20B increases uptake EXP SLC6A20B protein results in increased uptake of selenomethylselenocysteine CTD PMID:18845132 NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630 		JBrowse link
G Snap23 synaptosomal-associated protein 23 decreases expression ISO selenomethylselenocysteine results in decreased expression of SNAP23 mRNA CTD PMID:18514395 NCBI chr 2:120,398,137...120,436,829
Ensembl chr 2:120,398,152...120,431,736 		JBrowse link
G Sort1 sortilin 1 increases expression ISO selenomethylselenocysteine results in increased expression of SORT1 mRNA CTD PMID:18514395 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827 		JBrowse link
G Sp3 trans-acting transcription factor 3 multiple interactions ISO selenomethylselenocysteine metabolite promotes the reaction [SP3 protein binds to BMF promoter] CTD PMID:25321483 NCBI chr 2:72,766,774...72,810,790
Ensembl chr 2:72,766,771...72,810,790 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP selenomethylselenocysteine results in decreased expression of SPP1 protein CTD PMID:15318939 NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 multiple interactions ISO [selenomethylselenocysteine co-treated with Isoflavones] results in decreased activity of SRD5A1 protein CTD PMID:19025659 NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO selenomethylselenocysteine metabolite inhibits the reaction [STAT3 protein binds to BMF promoter]; STAT3 protein inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA] CTD PMID:25321483 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Stx3 syntaxin 3 increases expression ISO selenomethylselenocysteine results in increased expression of STX3 mRNA CTD PMID:18514395 NCBI chr19:11,752,482...11,798,933
Ensembl chr19:11,752,482...11,796,767 		JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions ISO [selenomethylselenocysteine results in decreased expression of BCL2 mRNA] which results in increased activity of TNFSF10 protein CTD PMID:19360359 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576 		JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 increases expression ISO selenomethylselenocysteine results in increased expression of TRNAU1AP mRNA CTD PMID:18514395 NCBI chr 4:132,039,074...132,058,007
Ensembl chr 4:132,039,074...132,056,849 		JBrowse link
G Xpa xeroderma pigmentosum, complementation group A multiple interactions ISO selenomethylselenocysteine inhibits the reaction [Zinc binds to XPA protein] CTD PMID:15265038 NCBI chr 4:46,175,222...46,196,317
Ensembl chr 4:46,155,347...46,196,311 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        pharmaceutical 21187
          drug 21159
            antineoplastic agent 18896
              Se-methylselenocysteine 77
                Se-methyl-D-selenocysteine + 0
                Se-methyl-L-selenocysteine + 76
                Se-methylselenocysteine residue + 0
                Se-methylselenocysteino group + 0
                Se-methylselenocysteinyl group + 0
                gamma-glutamyl-Se-methylselenocysteine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            inorganic hydride 18672
                              pnictogen hydride 18652
                                nitrogen hydride 18519
                                  azane 18426
                                    ammonia 18425
                                      organic amino compound 18425
                                        amino acid 16428
                                          non-proteinogenic amino acid 4035
                                            non-proteinogenic alpha-amino acid 3834
                                              Se-methylselenocysteine 77
                                                Se-methyl-D-selenocysteine + 0
                                                Se-methyl-L-selenocysteine + 76
                                                Se-methylselenocysteine residue + 0
                                                Se-methylselenocysteino group + 0
                                                Se-methylselenocysteinyl group + 0
                                                gamma-glutamyl-Se-methylselenocysteine 0
paths to the root