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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:scullcapflavone II
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Accession:CHEBI:9061 term browser browse the term
Definition:A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.
Synonyms:exact_synonym: 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
 related_synonym: 5,2'-dihydroxy-6,7,8,6'-tetramethoxyflavone;   5-hydroxy-2-(2-hydroxy-6-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-7-5-6-9(20)13(11)12-8-10(21)14-15(22)17(24-2)19(26-4)18(25-3)16(14)27-12/h5-8,20,22H,1-4H3;   InChIKey=GMQFOKBGMKVUQZ-UHFFFAOYSA-N;   SMILES=COc1cccc(O)c1-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1;   neobaicalein;   skullcapflavone II
 xref: CAS:55084-08-7;   KEGG:C10183;   KNApSAcK:C00001099;   LIPID_MAPS_instance:LMPK12111423
 xref_mesh: MESH:C047405
 xref: PMID:22314230;   PMID:25546119;   Reaxys:3634558

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scullcapflavone II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 affects binding ISO skullcapflavone II binds to CASP3 protein CTD PMID:32913905 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G Mapk14 mitogen activated protein kinase 14 affects binding ISO skullcapflavone II binds to MAPK14 protein CTD PMID:32913905 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
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  CHEBI ontology 19853
    role 19804
      application 19477
        anti-asthmatic agent 9189
          anti-asthmatic drug 8556
            scullcapflavone II 2
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  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic molecule 19568
                              organic cyclic compound 19378
                                organic heterocyclic compound 18495
                                  oxacycle 17279
                                    benzopyran 10142
                                      1-benzopyran 9858
                                        flavonoid 6375
                                          flavones 4170
                                            hydroxyflavone 4158
                                              dihydroxyflavone 477
                                                scullcapflavone II 2
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