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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:scullcapflavone II
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Accession:CHEBI:9061 term browser browse the term
Definition:A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.
Synonyms:exact_synonym: 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
 related_synonym: 5,2'-dihydroxy-6,7,8,6'-tetramethoxyflavone;   5-hydroxy-2-(2-hydroxy-6-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-7-5-6-9(20)13(11)12-8-10(21)14-15(22)17(24-2)19(26-4)18(25-3)16(14)27-12/h5-8,20,22H,1-4H3;   InChIKey=GMQFOKBGMKVUQZ-UHFFFAOYSA-N;   SMILES=COc1cccc(O)c1-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1;   neobaicalein;   skullcapflavone II
 xref: CAS:55084-08-7;   KEGG:C10183;   KNApSAcK:C00001099;   LIPID_MAPS_instance:LMPK12111423
 xref_mesh: MESH:C047405
 xref: PMID:22314230;   PMID:25546119;   Reaxys:3634558

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scullcapflavone II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 affects binding ISO skullcapflavone II binds to CASP3 protein CTD PMID:32913905 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G Mapk14 mitogen activated protein kinase 14 affects binding ISO skullcapflavone II binds to MAPK14 protein CTD PMID:32913905 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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  CHEBI ontology 20059
    role 20009
      application 19747
        anti-asthmatic agent 9254
          anti-asthmatic drug 8620
            scullcapflavone II 2
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  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic molecule 19819
                              organic cyclic compound 19581
                                organic heterocyclic compound 18804
                                  oxacycle 17704
                                    benzopyran 11204
                                      1-benzopyran 10945
                                        flavonoid 6568
                                          flavones 4216
                                            hydroxyflavone 4204
                                              dihydroxyflavone 491
                                                scullcapflavone II 2
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