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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:scullcapflavone II
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Accession:CHEBI:9061 term browser browse the term
Definition:A tetramethoxyflavone that is flavone substituted by methoxy groups at positions 6, 7, 8 and 6' and hydroxy groups at positons 5 and 2' respectively.
Synonyms:exact_synonym: 5-hydroxy-2-(2-hydroxy-6-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
 related_synonym: 5,2'-dihydroxy-6,7,8,6'-tetramethoxyflavone;   5-hydroxy-2-(2-hydroxy-6-methoxy-phenyl)-6,7,8-trimethoxy-chromen-4-one;   Formula=C19H18O8;   InChI=1S/C19H18O8/c1-23-11-7-5-6-9(20)13(11)12-8-10(21)14-15(22)17(24-2)19(26-4)18(25-3)16(14)27-12/h5-8,20,22H,1-4H3;   InChIKey=GMQFOKBGMKVUQZ-UHFFFAOYSA-N;   SMILES=COc1cccc(O)c1-c1cc(=O)c2c(O)c(OC)c(OC)c(OC)c2o1;   neobaicalein;   skullcapflavone II
 xref: CAS:55084-08-7;   KEGG:C10183;   KNApSAcK:C00001099;   LIPID_MAPS_instance:LMPK12111423
 xref_mesh: MESH:C047405
 xref: PMID:22314230;   PMID:25546119;   PMID:28886581;   PMID:31167359;   PMID:35398391;   PMID:36605189;   PMID:36697978;   PMID:36825003;   PMID:36865041;   PMID:37120983;   Reaxys:3634558



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scullcapflavone II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 affects binding ISO skullcapflavone II binds to CASP3 protein CTD PMID:32913905 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G Mapk14 mitogen activated protein kinase 14 affects binding ISO skullcapflavone II binds to MAPK14 protein CTD PMID:32913905 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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  CHEBI ontology 19918
    role 19894
      application 19729
        anti-asthmatic agent 9309
          anti-asthmatic drug 8686
            scullcapflavone II 2
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Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic heterocyclic compound 18906
                                  oxacycle 17850
                                    benzopyran 11796
                                      1-benzopyran 11539
                                        flavonoid 6906
                                          anthoxanthin 4541
                                            flavones 4541
                                              hydroxyflavone 4519
                                                dihydroxyflavone 536
                                                  scullcapflavone II 2
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